Isabel Gimeno

Boone, A. C., Kulkarni, R. R., Cortes, A. L., Gaghan, C., Mohammed, J., Villalobos, T., … Gimeno, I. M. (2024, February 1). Evaluation of Adjuvant Effect of Cytosine-Guanosine-Oligodeoxynucleotide in Meat-Type Chickens Coadministered <i>In Ovo</i> with Herpesvirus of Turkey Vaccine. VIRAL IMMUNOLOGY, Vol. 2. https://doi.org/10.1089/vim.2023.0125

Faiz, N. M., Cortes, A. L., Phang, Y.-fun, & Gimeno, I. M. (2024, March 21). Optimizing protocols for monitoring <i>in vivo</i> replication of a novel chimeric Marek's disease vaccine with an insertion of the long terminal repeat of reticuloendotheliosis virus in the CVI988 strain genome (CVI-LTR). AVIAN PATHOLOGY, Vol. 3. https://doi.org/10.1080/03079457.2024.2324930

Gaghan, C., Browning, M., Cortes, A. L., Gimeno, I. M., & Kulkarni, R. R. (2023). Effect of CpG-Oligonucleotide in Enhancing Recombinant Herpes Virus of Turkey-Laryngotracheitis Vaccine-Induced Immune Responses in One-Day-Old Broiler Chickens. VACCINES, 11(2). https://doi.org/10.3390/vaccines11020294

Gaghan, C., Browning, M., Fares, A. M., Abdul-Careem, M. F., Gimeno, I. M., & Kulkarni, R. R. (2023). In Ovo Vaccination with Recombinant Herpes Virus of the Turkey-Laryngotracheitis Vaccine Adjuvanted with CpG-Oligonucleotide Provides Protection against a Viral Challenge in Broiler Chickens. VIRUSES-BASEL, 15(10). https://doi.org/10.3390/v15102103

Boone, A. C., Kulkarni, R. R., Cortes, A. L., Villalobos, T., Esandi, J., & Gimeno, I. M. (2023). In ovo HVT vaccination enhances cellular responses at hatch and addition of poly I:C offers minimal adjuvant effects. VACCINE, 41(15), 2514–2523. https://doi.org/10.1016/j.vaccine.2023.02.076

Ellington, C., Cortes, A. L., Faiz, N. M., Mays, J. K., Fadly, A., Silva, R. F., & Gimeno, I. M. (2021, October 9). Characterization of Md5-BAC-REV-LTR virus as Marek's disease vaccine in commercial meat-type chickens: protection and immunosuppression. AVIAN PATHOLOGY, Vol. 10. https://doi.org/10.1080/03079457.2021.1970108

Salvador, C., Cortes, A. L., Pandiri, A. R., & Gimeno, I. M. (2021). Cytokine expression in the eye and brain of chickens following infection with a very virulent plus Marek's disease virus strain. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 237. https://doi.org/10.1016/j.vetimm.2021.110277

Gimeno, I. M., Shaw, W. N., Turner, A., Bremen, J., Cortes, A. L., Faiz, N. M., … Robbins, K. (2021). Replication of Marek's disease vaccines in turkey embryos and their effect on TLR-3 and IFN-gamma transcripts. AVIAN PATHOLOGY, 50(3), 227–233. https://doi.org/10.1080/03079457.2021.1882937

Liao, Y., Bajwa, K., Al-Mahmood, M., Gimeno, I. M., Reddy, S. M., & Lupiani, B. (2021). The role of Meq-vIL8 in regulating Marek's disease virus pathogenesis. JOURNAL OF GENERAL VIROLOGY, 102(2). https://doi.org/10.1099/jgv.0.001528

Boone, A. C., Kaser, T., Cortes, A. L., Kulkarni, R. R., Abad, B. A. L. de J., Villalobos, T., … Gimeno, I. M. (2020). In ovo vaccination with herpesvirus of turkey enhances innate and cellular responses in meat-type chickens: Effect of vaccine dose and strain. VACCINE, 38(31), 4837–4845. https://doi.org/10.1016/j.vaccine.2020.05.050

Gimeno, I. M. (2020). Marek's disease [Review of Marek’s disease, slide set #26, by I. M. Gimeno, R. L. Witter, & A. Miles]. American Association of Avian Pathologists.

Nair, V., Gimeno, I. M., & Dunn, J. R. (2020). Marek’s disease. In D. A. Swayne, D. Suarez, V. Nair, L. R. McDougald, M. Boulianne, C. Logue, … G. Zavala (Eds.), Diseases of Poultry (14th ed., pp. 550–587). https://doi.org/10.1002/9781119371199

Lopez de Juan Abad, B., Cortes, A. L., Correa, M., & Gimeno, I. M. (2019). Evaluation of factors that influence dose variability of Marek’s disease vaccines. Avian Diseases. https://doi.org/10.1637/aviandiseases-D-19-00097

Gimeno, I. M., Cortes, A. L., Reddy, S. M., Abad, B. L. de J., Kaser, T., & Limsatanun, A. (2019). Highly virulent Marek's disease virus strains affect T lymphocyte function and viability of splenocytes in commercial meat-type chickens. AVIAN PATHOLOGY, 48(6), 564–572. https://doi.org/10.1080/03079457.2019.1643451

Gimeno, I. M., Cortes, A. L., Reilley, A., Barbosa, T., Alvarado, I., Koopman, R., & Martinez, A. (2019). Study of Efficacy and Replication of Recombinant Vector Vaccines by Using Turkey Herpesvirus Combined with Other Marek's Disease Vaccines. AVIAN DISEASES, 63(2), 335–341. https://doi.org/10.1637/11987-103018-Reg.1

Faiz, N. M., Cortes, A. L., Guy, J. S., Reddy, S. M., & Gimeno, I. M. (2018). Differential attenuation of Marek's disease virus-induced tumours and late-Marek's disease virus-induced immunosuppression. JOURNAL OF GENERAL VIROLOGY, 99(7), 927–936. https://doi.org/10.1099/jgv.0.001076

Gimeno, I. M., Glaize, A., & Cortes, A. L. (2018). Effect of Marek’s disease vaccines on interferon and toll like receptors when administered in ovo. Veterinary Immunology and Immunopathology, 201, 62–66. https://doi.org/10.1016/j.vetimm.2018.05.012

Gall, S., Korosi, L., Cortes, A. L., Delvecchio, A., Prandini, F., Mitsch, P., & Gimeno, I. M. (2018). Use of real-time PCR to rule out Marek's disease in the diagnosis of peripheral neuropathy. AVIAN PATHOLOGY, 47(4), 427–433. https://doi.org/10.1080/03079457.2018.1473555

Gimeno, I. M., & Schat, K. A. (2018). Virus-Induced Immunosuppression in Chickens. Avian Diseases, 62(3), 272–285. https://doi.org/10.1637/11841-041318-review.1

Gimeno, I. M. (2017). Dissection of a Marek’s disease outbreak [Technical bulletin]. Lenexa, KS: CEVA.

Faiz, N. M., Cortes, A. L., Guy, J. S., Fletcher, O. J., Cimino, T., & Gimeno, I. M. (2017). Evaluation of factors influencing the development of late Marek's disease virus-induced immunosuppression: virus pathotype and host sex. AVIAN PATHOLOGY, 46(4), 376–385. https://doi.org/10.1080/03079457.2017.1290214

Gimeno, I. M. (2017). Marek's Disease Virus (Technical Bulletin No. 0417-AVN-065). Huntsville, AL: Aviagen International Ltd.

Gimeno, I. M. (2017). Marek’s disease control [Technical bulletin]. Lenexa, KS: CEVA.

Gimeno, I. M. (2017). Understanding Marek’s disease [Technical bulletin]. Lenexa, KS: CEVA.

Faiz, N. M., Cortes, A. L., Guy, J. S., Fletcher, O. J., West, M., Montiel, E., & Gimeno, I. M. (2016). Early infection with Marek's disease virus can jeopardize protection conferred by laryngotracheitis vaccines: a method to study MDV-induced immunosuppression. AVIAN PATHOLOGY, 45(6), 606–615. https://doi.org/10.1080/03079457.2016.1191618

Gimeno, I. M., Cortes, A. L., Faiz, N., Villalobos, T., Badillo, H., & Barbosa, T. (2016). Efficacy of Various HVT Vaccines (Conventional and Recombinant) Against Marek's Disease in Broiler Chickens: Effect of Dose and Age of Vaccination. AVIAN DISEASES, 60(3), 662–668. https://doi.org/10.1637/11415-040116-reg.1

Faiz, N. M., Cortes, A. L., Guy, J. S., Fogle, J. E., & Gimeno, I. M. (2016). Efficacy of various Marek's disease vaccines protocols for prevention of Marek's disease virus-induced immunosuppression. VACCINE, 34(35), 4180–4187. https://doi.org/10.1016/j.vaccine.2016.06.061

Gimeno, I. M., & Walkenell, P. (2016). Marek’s disease. In S. Williams (Ed.), A laboratory manual for the isolation, identification and characterization of avian pathogens (6th ed.). Jacksonville, FL: American Association of Avian Pathologists.

Gimeno, I. M., Cortes, A. L., Faiz, N. M., Barbosa, T., & Villalobos, T. (2015). Evaluation of Factors Influencing Efficacy of Vaccine Strain CVI988 Against Marek's Disease in Meat-Type Chickens. AVIAN DISEASES, 59(3), 400–409. https://doi.org/10.1637/11085-040915-reg.1

Gimeno, I. M., Cortes, A. L., Faiz, N. M., Hernandez-Ortiz, B. A., Guy, J. S., Hunt, H. D., & Silva, R. F. (2015). Evaluation of the Protection Efficacy of a Serotype 1 Marek's Disease Virus-Vectored Bivalent Vaccine Against Infectious Laryngotracheitis and Marek's Disease. Avian Diseases, 59(2), 255–262. https://doi.org/10.1637/10966-103014-reg

Gimeno, I. M., Faiz, N. M., Cortes, A. L., Barbosa, T., Villalobos, T., & Pandiri, A. R. (2015). In Ovo Vaccination with Turkey Herpesvirus Hastens Maturation of Chicken Embryo Immune Responses in Specific-Pathogen-Free Chickens. AVIAN DISEASES, 59(3), 375–383. https://doi.org/10.1637/11060-031115-reg.1

Rochon, K., Baker, R. B., Almond, G. W., Gimeno, I. M., De Leon, A. A. P., & Watson, D. W. (2015). Persistence and Retention of Porcine Reproductive and Respiratory Syndrome Virus in Stable Flies (Diptera: Muscidae). JOURNAL OF MEDICAL ENTOMOLOGY, 52(5), 1117–1123. https://doi.org/10.1093/jme/tjv096

Gimeno, I. M., Dunn, J. R., Cortes, A. L., El-Gohary, A. E.-G., & Silva, R. F. (2014). Detection and Differentiation of CVI988 (Rispens Vaccine) from Other Serotype 1 Marek's Disease Viruses. AVIAN DISEASES, 58(2), 232–243. https://doi.org/10.1637/10666-091713-reg.1

Gimeno, I. M. (2014). Marek’s Disease and Differential Diagnosis with Other Tumor Viral Diseases of Poultry. In N. K. Van Alfen (Ed.), Encyclopedia of Agriculture and Food Systems (pp. 156–171). London, UK: Academic Press/Elsevier.

Dunn, J. R., & Gimeno, I. M. (2013, June). Current Status of Marek's Disease in the United States and Worldwide Based on a Questionnaire Survey. AVIAN DISEASES, Vol. 57, pp. 483–490. https://doi.org/10.1637/10373-091412-resnote.1

Gimeno, I. M., & Pandiri, A. R. (2013). Virus-induced immunosuppression: Marek’s disease virus infection and associated syndromes. In I. M. Gimeno (Ed.), Immunosuppressive diseases of poultry (pp. 124–152). Zaragoza, Spain: Servet, Grupo Asís Biomedia, S.L.

Fletcher, O. J., Tan, X., Cortes, L., & Gimeno, I. (2012). Cost effective and time efficient measurement of CD4, CD8, major histocompatibility complex Class II, and macrophage antigen expression in the lungs of chickens. Veterinary Immunology and Immunopathology, 146(3-4), 225–236. https://doi.org/10.1016/j.vetimm.2012.03.007

Spatz, S. J., Volkening, J. D., Gimeno, I. M., Heidari, M., & Witter, R. L. (2012). Dynamic equilibrium of Marek's disease genomes during in vitro serial passage. VIRUS GENES, 45(3), 526–536. https://doi.org/10.1007/s11262-012-0792-z

Gimeno, I. M., Cortes, A. L., Witter, R. L., & Pandiri, A. R. (2012). Optimization of the Protocols for Double Vaccination Against Marek's Disease by Using Commercially Available Vaccines: Evaluation of Protection, Vaccine Replication, and Activation of T Cells. AVIAN DISEASES, 56(2), 295–305. https://doi.org/10.1637/9930-091311-reg.1

Pandiri, A. R., Gimeno, I. M., Mays, J. K., Reed, W. M., & Fadly, A. M. (2012). Reversion to Subgroup J Avian Leukosis Virus Viremia in Seroconverted Adult Meat-Type Chickens Exposed to Chronic Stress by Adrenocorticotrophin Treatment. AVIAN DISEASES, 56(3), 578–582. https://doi.org/10.1637/9949-092611-resnote.1

Gimeno, I. M., Witter, R. L., Cortes, A. L., Reddy, S. M., & Pandiri, A. R. (2012). Standardization of a model to study revaccination against Marek's disease under laboratory conditions. Avian Pathology, 41(1), 59–68. https://doi.org/10.1080/03079457.2011.635636

Gimeno, I. M., & Cortes, A. L. (2011). Chronological study of cytokine transcription in the spleen and lung of chickens after vaccination with serotype 1 Marek's disease vaccines. VACCINE, 29(8), 1583–1594. https://doi.org/10.1016/j.vaccine.2010.12.079

Cortes, A. L., Montiel, E. R., Lemiere, S., & Gimeno, I. M. (2011). Comparison of Blood and Feather Pulp Samples for the Diagnosis of Marek's Disease and for Monitoring Marek's Disease Vaccination by Real Time-PCR. AVIAN DISEASES, 55(2), 302–310. https://doi.org/10.1637/9578-101510-resnote.1

Gimeno, I. M., Cortes, A. L., Montiel, E. R., Lemiere, S., & Pandiri, A. K. R. (2011). Effect of Diluting Marek's Disease Vaccines on the Outcomes of Marek's Disease Virus Infection When Challenged with Highly Virulent Marek's Disease Viruses. AVIAN DISEASES, 55(2), 263–272. https://doi.org/10.1637/9579-101510-reg.1

Gimeno, I. M., Witter, R. L., Cortes, A. L., & Reed, W. M. (2011). Replication ability of three highly protective Marek's disease vaccines: implications in lymphoid organ atrophy and protection. AVIAN PATHOLOGY, 40(6), 573–579. https://doi.org/10.1080/03079457.2011.617725

Gimeno, I. M., Cortes, A. L., Guy, J. S., Turpin, E., & Williams, C. (2011). Replication of recombinant herpesvirus of turkey expressing genes of infectious laryngotracheitis virus in specific pathogen free and broiler chickens following in ovo and subcutaneous vaccination. AVIAN PATHOLOGY, 40(4), 395–403. https://doi.org/10.1080/03079457.2011.588196

Gimeno, I. M., & Cortes, A. L. (2010). Evaluation of factors influencing replication of serotype 1 Marek's disease vaccines in the chicken lung. AVIAN PATHOLOGY, 39(2), 71–79. https://doi.org/10.1080/03079451003599250

Witter, R. L., Gimeno, I. M., Pandiri, A. K., & Fadly, A. M. (2010). Tumor diagnosis manual: The differential diagnosis of lymphoid and myeloid tumors in the chicken (First Edition). Jacksonville, Florida: American Association of Avian Pathologists.

Gimeno, I. M. (2009). Enfermedad de Marek. In A. J. P. Ferreira & L. Revolledo (Eds.), Principios Basicos de Patologia Aviar (pp. 193–228). Guanabara Koogan, Brazil.

Pandiri, A. R., Gimeno, I. M., Reed, W. M., Fitzgerald, S. D., & Fadly, A. M. (2009). Subgroup J Avian Leukosis Virus-Induced Histiocytic Sarcomatosis Occurs Only in Persistently Viremic but Not Immunotolerized Meat-type Chickens. VETERINARY PATHOLOGY, 46(2), 282–287. https://doi.org/10.1354/vp.46-2-282

Cortes, A. L., Montiel, E. R., & Gimeno, I. M. (2009). Validation of Marek's Disease Diagnosis and Monitoring of Marek's Disease Vaccines from Samples Collected in FTA (R) Cards. AVIAN DISEASES, 53(4), 510–516. https://doi.org/10.1637/8871-041009-Reg.1

Gimeno, I., & Silva, R. F. (2008). Deletion of the Marek’s disease virus UL41 gene (vhs) has no measurable effect on latency or pathogenesis. Virus Genes, 36(3), 499–507. https://doi.org/10.1007/s11262-008-0215-3

Pandiri, A. R., Gimeno, I. M., Reed, W. M., Lee, L. F., Silva, R. F., & Fadly, A. M. (2008). Distribution of viral antigen gp85 and provirus in various tissues from commercial meat-type and experimental White Leghorn Line 0 chickens with different subgroup J avian leukosis virus infection profiles. Avian Pathology, 37(1), 7–13. https://doi.org/10.1080/03079450701774843

Spatz, S. J., Gimeno, I. M., & Heidari, M. (2008). Identification of Marek's disease virus genes mutated during serial passage-induced attenuation. Vaccine.

Gimeno, I. M., Cortes, A. L., & Silva, R. F. (2008). Load of Challenge Marek's Disease Virus DNA in Blood as a Criterion for Early Diagnosis of Marek's Disease Tumors. AVIAN DISEASES, 52(2), 203–208. https://doi.org/10.1637/8089-081407-Reg.1

Pandiri, A. K. R., Cortes, A. L., Lee, L. F., & Gimeno, I. M. (2008). Marek's Disease Virus Infection in the Eye: Chronological Study of the Lesions, Virus Replication, and Vaccine-Induced Protection. AVIAN DISEASES, 52(4), 572–580. https://doi.org/10.1637/8284-031308-Reg.1

Gimeno, I. M. (2008). [Review of Marek's disease vaccines: A solution for today but a worry for tomorrow?]. VACCINE, 26, C31–C41. https://doi.org/10.1016/j.vaccine.2008.04.009

Silva, R. F., & Gimeno, I. (2007). Oncogenic Marek’s disease viruses lacking the 132 base pair repeats can still be attenuated by serial in vitro cell culture passages. Virus Genes, 34(1), 87–90. https://doi.org/10.1007/s11262-006-0022-7

Witter, R. L., & Gimeno, I. M. (2006). Susceptibility of Adult Chickens, With and Without Prior Vaccination, to Challenge with Marek's Disease Virus. Avian Diseases, 50(3), 354–365. https://doi.org/10.1637/7498-010306r.1

Lee, L. F., Cui, X., Cui, Z., Gimeno, I., Lupiani, B., & Reddy, S. M. (2005). Characterization of a very Virulent Marek’s Disease Virus Mutant Expressing the pp38 Protein from the Serotype 1 Vaccine Strain CVI988/Rispens. Virus Genes, 31(1), 73–80. https://doi.org/10.1007/s11262-005-2202-2

Witter, R. L., Calnek, B. W., Buscaglia, C., Gimeno, I. M., & Schat, K. A. (2005). Classification of Marek's disease viruses according to pathotype: philosophy and methodology. Avian Pathology, 34(2), 75–90. https://doi.org/10.1080/03079450500059255

Gimeno, I. M., Witter, R. L., & Miles, A. (2005). Marek’s disease (Slide Study Set No. 26). Jacksonville, FL: American Association of Avian Pathologists.

Gimeno, I. M., Witter, R. L., Fadly, A. M., & Silva, R. F. (2005). Novel criteria for the diagnosis of Marek's disease virus-induced lymphomas. Avian Pathology, 34(4), 332–340. https://doi.org/10.1080/03079450500179715

Gimeno, I. M., Witter, R. L., Hunt, H. D., Reddy, S. M., Lee, L. F., & Silva, R. F. (2005). The pp38 Gene of Marek's Disease Virus (MDV) Is Necessary for Cytolytic Infection of B Cells and Maintenance of the Transformed State but Not for Cytolytic Infection of the Feather Follicle Epithelium and Horizontal Spread of MDV. Journal of Virology, 79(7), 4545–4549. https://doi.org/10.1128/jvi.79.7.4545-4549.2005

M. Gimeno, I., Witter, R. L., Hunt, H. D., Reddy, S. M., & Reed, W. M. (2004). Biocharacteristics shared by highly protective vaccines against Marek's disease. Avian Pathology, 33(1), 57–66. https://doi.org/10.1080/0307945031000163264

Gimeno, I. M. (2004). Future strategies for controlling Marek's disease. In Marek's Disease (pp. 186-x). https://doi.org/10.1016/b978-012088379-0/50018-9

Lupiani, B., Lee, L. F., Cui, X., Gimeno, I., Anderson, A., Morgan, R. W., … al. (2004). Marek's disease virus-encoded Meq gene is involved in transformation of lymphocytes but is dispensable for replication. Proceedings of the National Academy of Sciences, 101(32), 11815–11820. https://doi.org/10.1073/pnas.0404508101

Gimeno, I. M., Witter, R. L., & Neumann, U. (2002). Neuropathotyping: A New System to Classify Marek's Disease Virus. Avian Diseases, 46(4), 909–918. https://doi.org/10.1637/0005-2086(2002)046[0909:NANSTC]2.0.CO;2

González, M., Rodriguez-Bertos, A., Gimeno, I., Flores, J. M., & Pizarro, M. (2002). Outbreak of Avian Tuberculosis in 48-Week-Old Commercial Layer Hen Flock. Avian Diseases, 46(4), 1055–1061. https://doi.org/10.1637/0005-2086(2002)046[1055:ooatiw]2.0.co;2

Reddy, S. M., Lupiani, B., Gimeno, I. M., Silva, R. F., Lee, L. F., & Witter, R. L. (2002). Rescue of a pathogenic Marek's disease virus with overlapping cosmid DNAs: Use of a pp38 mutant to validate the technology for the study of gene function. Proceedings of the National Academy of Sciences, 99(10), 7054–7059. https://doi.org/10.1073/pnas.092152699

Gimeno, I. M., Witter, R. L., Hunt, H. D., Reddy, S. M., & Neumann, U. (2001). Differential attenuation of the induction by Marek's disease virus of transient paralysis and persistent neurological disease: A model for pathogenesis studies. Avian Pathology, 30(4), 397–409. https://doi.org/10.1080/03079450120066403

Hunt, H. D., Lupiani, B., Miller, M. M., Gimeno, I., Lee, L. F., & Parcells, M. S. (2001). Marek's Disease Virus Down-Regulates Surface Expression of MHC (B Complex) Class I (BF) Glycoproteins during Active but not Latent Infection of Chicken Cells. Virology, 282(1), 198–205. https://doi.org/10.1006/viro.2000.0797

Gimeno, I. M., Witter, R. L., Hunt, H. D., Lee, L. F., Reddy, S. M., & Neumann, U. (2001). Marek's Disease Virus Infection in the Brain: Virus Replication, Cellular Infiltration, and Major Histocompatibility Complex Antigen Expression. Veterinary Pathology, 38(5), 491–503. https://doi.org/10.1354/vp.38-5-491

Reddy, S. M., Witter, R. L., & Gimeno, I. (2000). Development of a Quantitative-Competitive Polymerase Chain Reaction Assay for Serotype 1 Marek's Disease Virus. Avian Diseases, 44(4), 770. https://doi.org/10.2307/1593048

Witter, R. L., Gimeno, I. M., Reed, W. M., & Bacon, L. D. (1999). An Acute Form of Transient Paralysis Induced by Highly Virulent Strains of Marek's Disease Virus. Avian Diseases, 43(4), 704. https://doi.org/10.2307/1592740

Voelckel, K., Bertram, E., Gimeno, I. M., Neumann, U., & Kaleta, E. F. (1999). Evidence for Marek's disease in turkeys in Germany: Detection of MDVH serotype 1 using the polymerase chain reaction. Acta Virologica, 43, 143–147.

Gimeno, I. M., Witter, R. L., & Reed, W. M. (1999). Four Distinct Neurologic Syndromes in Marek's Disease: Effect of Viral Strain and Pathotype. Avian Diseases, 43(4), 721. https://doi.org/10.2307/1592741