Works (54)
Updated: October 25th, 2024 11:30
2024 journal article
Conserved plant transcriptional responses to microgravity from two consecutive spaceflight experiments
FRONTIERS IN PLANT SCIENCE, 14.
author keywords: transcriptional profiling; adaptation to spaceflight; Arabidopsis; microgravity (mu g); plants
TL;DR:
Two separate spaceflight experiments conducted on the International Space Station uncovered microgravity unique transcriptional changes and highlight the validity and importance of an onboard 1 g control.
(via Semantic Scholar)
open access via www.frontiersin.org (publisher PDF)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 1, 2024
2023 journal article
Arabidopsis telomerase takes off by uncoupling enzyme activity from telomere length maintenance in space
NATURE COMMUNICATIONS, 14(1).
TL;DR:
No changes in telomere length in space-flown Arabidopsis seedlings are observed, despite a dramatic increase in telomerase activity (up to 150-fold in roots), as well as elevated genome oxidation, and it is proposed that genome oxidation is inversely correlated with telomersase activity levels.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: November 30, 2023
2023 journal article
Bridging the gap: parallel profiling of ribosome associated and total RNA species can identify transcriptional regulatory mechanisms of plants in spaceflight
JOURNAL OF PLANT INTERACTIONS, 18(1).
author keywords: Spaceflight; transcriptomics; translatomics; TRAP; Arabidopsis thaliana
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: August 29, 2023
2023 journal article
Meta-analysis of the space flight and microgravity response of the Arabidopsis plant transcriptome
NPJ MICROGRAVITY, 9(1).
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: April 11, 2023
2023 journal article
Regulation of inositol 1,2,4,5,6-pentakisphosphate and inositol hexakisphosphate levels in Gossypium hirsutum by IPK1
PLANTA, 257(2).
author keywords: Cotton; Inositol phosphates; Kinases; Malvaceae; Phytic acid; VIGS
MeSH headings : Phytic Acid / metabolism; Gossypium / genetics; Gossypium / metabolism; Inositol Phosphates / metabolism; Inositol Phosphates / pharmacology
TL;DR:
The central role of IPK1 is detailed in cotton inositol polyphosphate metabolism, which has potential to be harnessed to improve the resistance of plants to different kinds of stress.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: February 20, 2023
2021 journal article
A Role for Inositol Pyrophosphates in the Metabolic Adaptations to Low Phosphate in Arabidopsis
METABOLITES, 11(9).
author keywords: inositol pyrophosphates; phosphate starvation response; phosphate homeostasis; lipid remodeling; AtVIP1; AtVIP2
TL;DR:
Evidence that both local and systemic responses to phosphate limitation are dampened in the vip1/vip2 mutants as compared to wild-type plants is presented, providing insight on the nexus between inositol phosphates and pyrophosphates involved in complex regulatory mechanisms underpinning phosphate homeostasis in plants.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: September 8, 2021
2021 article
Evaluating the Effects of the Circadian Clock and Time of Day on Plant Gravitropic Responses
PLANT GRAVITROPISM, Vol. 2368, pp. 301–319.
author keywords: Circadian; Gravistimulation; Time of day; Diel; Simulated microgravity
MeSH headings : Arabidopsis / metabolism; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Circadian Clocks; Circadian Rhythm; Gene Expression Regulation, Plant; Gravitropism; Photoperiod
TL;DR:
It is critical to consider the time of day when performing gravitropism experiments, even if the circadian clock is not a focus of study.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science; OpenAlex)
13. Climate Action
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: October 14, 2021
2021 journal article
NASA GeneLab RNA-seq consensus pipeline: standardized processing of short-read RNA-seq data
ISCIENCE, 24(4).
TL;DR:
Members of NASA GeneLab and GeneLab-associated analysis working groups have developed a consensus pipeline for analyzing short-read RNA-sequencing data from spaceflight-associated experiments, culminating in the detection of differentially expressed genes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: June 10, 2021
2021 journal article
The Circadian-clock Regulates the Arabidopsis Gravitropic Response
Gravitational and Space Research.
TL;DR:
Gravitropic responses were disrupted in plants with disrupted circadian clocks, including plants overexpressing Circadian-clock Associated 1 (CCA1) and elf3-2, in the reorientation assay and on a 2D clinostat suggesting the variation is circadian-regulated.
(via Semantic Scholar)
Source: ORCID
Added: January 6, 2022
2021 journal article
Uncovering Transcriptional Responses to Fractional Gravity in Arabidopsis Roots
LIFE-BASEL, 11(10).
author keywords: spaceflight; fractional gravity; RNA-seq; Arabidopsis; gene expression; heat shock proteins
TL;DR:
A subset of genes whose expression correlates with changes in fractional g include those encoding transcription factors, defense, and cell wall-related proteins and heat shock proteins, which are likely to be responsive to gravity changes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: September 28, 2021
2015 journal article
Biosynthesis and possible functions of inositol pyrophosphates in plants
FRONTIERS IN PLANT SCIENCE, 6.
author keywords: plant inositol signaling; inositol hexakisphosphate; VIP; inositol pyrophosphate; energy metabolism
TL;DR:
This review will detail the known roles of PPx-InsPs in yeast and animal systems, and provide a description of recent data on the synthesis and accumulation of these novel molecules in plants, and potential roles in signaling.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2015 journal article
Certain Malvaceae Plants Have a Unique Accumulation of myo-Inositol 1,2,4,5,6-Pentakisphosphate
Plants, 4(2), 267–283.
TL;DR:
A method was developed to concentrate and pre-purify inositol phosphates in leaves of different plants prior to analysis, which permitted the determination of InsP6 and InsP5 concentrations in leaves as low as 10 µM and 2 µM, respectively.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 25, 2020
2015 chapter
Methods for RNA Profiling of Gravi-Responding Plant Tissues
In Methods in Molecular Biology (Vol. 1309, pp. 91–117).
Contributors: J. Dalal n, E. Land n , N. Vasani n, L. He n, C. Smith n, M. Rodriguez-Welsh n, n , H. Sederoff n
author keywords: RNA; Transcript; Transcriptome; Sequencing; PCR; RNAseq; sRNA; miRNA
MeSH headings : Gene Expression Profiling / methods; Gene Expression Regulation, Plant; Gravity Sensing / genetics; Oligonucleotide Array Sequence Analysis / methods; RNA / genetics; RNA, Messenger / biosynthesis; RNA, Messenger / genetics; Seeds / genetics; Seeds / growth & development; Transcriptome / genetics
TL;DR:
The current and most widely used methods to profile the changes in an entire transcriptome by high-throughput sequencing of RNA fractions (RNAseq) and single gene transcript analysis using real-time quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR) are described.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018
2014 journal article
Do phosphoinositides regulate membrane water permeability of tobacco protoplasts by enhancing the aquaporin pathway?
Planta, 241(3), 741–755.
author keywords: BY2; Lipid; Osmotic water permeability coefficient; P-f; Signaling; Synthetic-biology
MeSH headings : Aquaporins / metabolism; Cell Membrane Permeability; Cells, Cultured; Cytosol / metabolism; Hydrogen-Ion Concentration; Phosphatidylinositols / metabolism; Protoplasts; Tobacco; Water / metabolism
TL;DR:
Three results demonstrate the differences between the PIPK cells and their controls, and suggest a hitherto unobserved regulation of aquaporins by phosphoinositides, which could occur through direct interaction or indirect phosphoinosis-dependent cellular effects.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Phosphoinositide-signaling is one component of a robust plant defense response
Frontiers in Plant Science, 5.
author keywords: Arabidopsis; Ca2+; salicylic acid; phosphoinositides; InsP(3); plant defense signaling; SAR
TL;DR:
The dampening of InsP3-mediated signaling affects Ca2+ release, modulates defense gene expression and compromises plant defense responses, shows that phosphoinositide signaling is one component of the plant defense network and is involved in both basal and systemic responses.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Two inositol hexakisphosphate kinases drive inositol pyrophosphate synthesis in plants
The Plant Journal, 80(4), 642–653.
author keywords: Arabidopsis thaliana; At3g01310; At5g15070; inositol pyrophosphate; inositol kinase; InsP(6)
MeSH headings : Arabidopsis / genetics; Arabidopsis / metabolism; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Chromatography, High Pressure Liquid; Genetic Complementation Test; Inositol Phosphates / metabolism; Mutation; Phosphotransferases (Alcohol Group Acceptor) / genetics; Phosphotransferases (Alcohol Group Acceptor) / metabolism; Phosphotransferases (Phosphate Group Acceptor) / genetics; Phosphotransferases (Phosphate Group Acceptor) / metabolism; Phylogeny; Plant Proteins / genetics; Plant Proteins / metabolism; Seeds / metabolism; Transcription Factors, General / genetics; Transcription Factors, General / metabolism; Yeasts / genetics; Zea mays / genetics; Zea mays / metabolism
TL;DR:
It is reported that Arabidopsis and maize InsP6 transporter mutants have elevated levels of inositol pyrophosphates in their seed, providing unequivocal identification of their presence in plant tissues and it is shown that plant seeds store a little over 1% of their inositl phosphate pool as InsP7 and InsP8.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2013 chapter
Measurement of Inositol (1,4,5) Trisphosphate in Plant Tissues by a Competitive Receptor Binding Assay
In Methods in Molecular Biology (pp. 33–41).
MeSH headings : Arabidopsis / metabolism; Binding, Competitive; Biological Assay / methods; Inositol 1,4,5-Trisphosphate / metabolism; Inositol 1,4,5-Trisphosphate Receptors / metabolism; Organ Specificity; Protein Binding; Seedlings / metabolism; Tritium
TL;DR:
This chapter describes a protocol for extracting and neutralizing plant samples and performing the receptor binding assay (using a commercially available kit) and has been used effectively to monitor InsP3 levels in plant tissues of different origin and in response to different stresses.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 25, 2020
2013 journal article
Phosphatidylinositol 4,5-Bisphosphate Influences PIN Polarization by Controlling Clathrin-Mediated Membrane Trafficking in Arabidopsis
The Plant Cell, 25(12), 4894–4911.
MeSH headings : Arabidopsis / cytology; Arabidopsis / genetics; Arabidopsis / growth & development; Arabidopsis / metabolism; Arabidopsis Proteins / analysis; Arabidopsis Proteins / metabolism; Biological Transport; Cell Polarity; Clathrin-Coated Vesicles / physiology; Endocytosis; Green Fluorescent Proteins / analysis; Indoleacetic Acids / metabolism; Membrane Transport Proteins / analysis; Membrane Transport Proteins / metabolism; Mutation; Phenotype; Phosphatidylinositol 4,5-Diphosphate / physiology; Phosphotransferases (Alcohol Group Acceptor) / genetics
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2013 chapter
Phosphatidylinositol 4-Kinase and Phosphatidylinositol 4-Phosphate 5-Kinase Assays
In Methods in Molecular Biology (pp. 163–174).
MeSH headings : 1-Phosphatidylinositol 4-Kinase / metabolism; Enzyme Assays / methods; Phosphotransferases (Alcohol Group Acceptor) / metabolism; Plants / enzymology
TL;DR:
Current protocols for monitoring lipid kinase-specific activity are summarized and important considerations for working with inositol lipids including different methods for substrate delivery when using recombinant proteins are identified.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 25, 2020
2012 journal article
A ROLE FOR LIPID-MEDIATED SIGNALING IN PLANT GRAVITROPISM
AMERICAN JOURNAL OF BOTANY, 100(1), 153–160.
author keywords: auxin; calcium; gravitropism; InsP(3); lipid signaling
MeSH headings : Gravitropism / physiology; Indoleacetic Acids / metabolism; Lipid Metabolism; Phosphatidylinositols / metabolism; Plants / metabolism; Signal Transduction
TL;DR:
This thesis is that membrane lipids and lipid-mediated signaling pathways play critical roles in the initial signaling and in the establishment of polarity in Gravitropism.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 journal article
A Role for Phosphoinositides in Regulating Plant Nuclear Functions
Frontiers in Plant Science, 3.
author keywords: nucleus; phosphoinositide; inositol phosphate; phosphatidylinositol; plant; signaling; chromatin remodeling
TL;DR:
In this review, the potential functions of the nuclear PI pathway in plants are discussed within the context of the animal and yeast literature and it is anticipated that future research will help shed light on the functional significance of thenuclear PI pathways in plants.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: January 25, 2020
2010 journal article
Basal Signaling Regulates Plant Growth and Development
PLANT PHYSIOLOGY, 154(2), 439–443.
Contributors: W. Boss n, H. Sederoff n , Y. Im n, N. Moran n, A. Grunden n & n
MeSH headings : Plant Development; Plant Physiological Phenomena; Second Messenger Systems
TL;DR:
The term signal transduction refers to the classical paradigm where an external stimulus is sensed and initiates an increase in second messengers and each second messenger transmits and amplifies the signal by activating a subset of downstream pathways.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science; OpenAlex)
13. Climate Action
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2010 journal article
Role of inositol 1,4,5-triphosphate signalling in gravitropic and phototropic gene expression
Plant, Cell & Environment, 33(12), 2041–2055.
Contributors: R. Salinas-Mondragon, J. Kajla n, n , C. Brown n & H. Sederoff n
author keywords: gravitropism; inositol phosphate; phospholipase C; photomorphogenesis; phototropism; transcription
MeSH headings : Arabidopsis / genetics; Arabidopsis / growth & development; Arabidopsis / metabolism; Gene Expression Regulation, Plant; Gravitropism; Hypocotyl / growth & development; Inositol 1,4,5-Trisphosphate / metabolism; Phototropism; Plant Roots / metabolism; Plants, Genetically Modified / growth & development; Plants, Genetically Modified / metabolism; Signal Transduction; Type C Phospholipases / metabolism
TL;DR:
It is concluded that changes in gene expression in response to gravitropic and phototropic stimulation are mediated by two signal transduction pathways that vary in their dependence on changes in InsP(3).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Crossref, NC State University Libraries, ORCID
Added: January 19, 2020
2010 chapter
The Hull of Fame: Lipid Signaling in the Plasma Membrane
In The Plant Plasma Membrane (pp. 437–455).
TL;DR:
This chapter will summarize the major findings on plant PI signaling and on the emerging signaling role of sphingolipids.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 21, 2021
2009 journal article
Increasing inositol (1,4,5)-trisphosphate metabolism affects drought tolerance, carbohydrate metabolism and phosphate-sensitive biomass increases in tomato
Plant Biotechnology Journal, 8(2), 170–183.
Contributors: M. Khodakovskaya*, C. Sword*, Q. Wu n, n , W. Boss n, C. Brown n, H. Winter Sederoff
MeSH headings : Biomass; Carbohydrate Metabolism; Carotenoids / metabolism; Cytosol / metabolism; DNA, Plant / genetics; Droughts; Fruit / growth & development; Fruit / metabolism; Gene Expression Profiling; Gene Expression Regulation, Plant; Hexoses / metabolism; Humans; Hydrolysis; Inositol 1,4,5-Trisphosphate / metabolism; Inositol Polyphosphate 5-Phosphatases; Lycopene; Solanum lycopersicum / genetics; Solanum lycopersicum / growth & development; Solanum lycopersicum / metabolism; Oligonucleotide Array Sequence Analysis; Phosphoric Monoester Hydrolases / genetics; Plant Leaves / metabolism; Plants, Genetically Modified / genetics; Plants, Genetically Modified / growth & development; Plants, Genetically Modified / metabolism
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: NC State University Libraries, NC State University Libraries, ORCID
Added: August 6, 2018
2009 chapter
InsP3 in Plant Cells
In Lipid Signaling in Plants (pp. 145–160).
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: January 21, 2021
2008 journal article
Phosphatidylinositol (4,5)Bisphosphate Inhibits K+-Efflux Channel Activity in NT1 Tobacco Cultured Cells
PLANT PHYSIOLOGY, 149(2), 1127–1140.
MeSH headings : Abscisic Acid / pharmacology; Calcium / pharmacology; Calcium / physiology; Cells, Cultured; Drosophila Proteins / drug effects; Drosophila Proteins / physiology; Kinetics; Phosphatidylinositol 4,5-Diphosphate / metabolism; Phosphatidylinositol 4,5-Diphosphate / pharmacology; Potassium / physiology; Potassium Channel Blockers / pharmacology; Potassium Channels / drug effects; Potassium Channels / physiology; Potassium Channels, Tandem Pore Domain / antagonists & inhibitors; Potassium Channels, Tandem Pore Domain / physiology; Tobacco / cytology; Tobacco / drug effects; Tobacco / physiology
TL;DR:
Short-term manipulations decreasing PtdInsP2 levels in the High PIs, such as pretreatment with the phytohormone abscisic acid or neutralizing the bath solution from pH 5.6 to pH 7, increased IK (i.e. Ntork activity), consistent with NtORK inhibition by the negatively charged PtdinsP2 in the internal plasma membrane leaflet.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
3. Good Health and Well-being
(OpenAlex)
13. Climate Action
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2008 review
Transgenic Arabidopsis Plants Expressing the Type 1 Inositol 5-Phosphatase Exhibit Increased Drought Tolerance and Altered Abscisic Acid Signaling
[Review of ]. PLANT CELL, 20(10), 2876–2893.
MeSH headings : Abscisic Acid / metabolism; Abscisic Acid / pharmacology; Animals; Arabidopsis / drug effects; Arabidopsis / genetics; Arabidopsis / physiology; Calcium / metabolism; Droughts; Gene Expression Profiling; Inositol Polyphosphate 5-Phosphatases; Oligonucleotide Array Sequence Analysis; Phosphoric Monoester Hydrolases / metabolism; Plants, Genetically Modified / metabolism; Signal Transduction; Water / metabolism
TL;DR:
The results indicate that the drought tolerance of the InsP 5-ptase plants is mediated in part via a DREB2A-dependent pathway and that constitutive dampening of theInsP3 signal reveals unanticipated interconnections between signaling pathways.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
13. Climate Action
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2007 journal article
Increasing plasma membrane phosphatidylinositol(4,5)bisphosphate biosynthesis increases phosphoinositide metabolism in Nicotiana tabacum
PLANT CELL, 19(5), 1603–1616.
MeSH headings : Basal Metabolism; Calcium / metabolism; Cell Membrane / enzymology; Cell Membrane / metabolism; Cell Respiration; Green Fluorescent Proteins / metabolism; Humans; Inositol 1,4,5-Trisphosphate / metabolism; Lipid Metabolism; Phosphatidylinositol 4,5-Diphosphate / biosynthesis; Plant Proteins / metabolism; Plants, Genetically Modified; Protein Transport; Recombinant Fusion Proteins / metabolism; Subcellular Fractions / metabolism; Tobacco / cytology; Tobacco / enzymology; Tobacco / genetics; Tobacco / metabolism; Tritium
TL;DR:
It is demonstrated that PIPK is flux limiting and that this high rate of PI metabolism increased the energy demands in transgenic tobacco cells.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
3. Good Health and Well-being
(OpenAlex)
13. Climate Action
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2007 conference paper
Quality Assessment of Affymetrix GeneChip Data using the EM Algorithm and a Naive Bayes Classifier
2007 IEEE 7th International Symposium on BioInformatics and BioEngineering, 145–150.
Contributors: B. Howard n, B. Sick n, n , J. Yang n, H. Winter-Sederoff & S. Heber n
Event: 2007 IEEE 7th International Symposium on BioInformatics and BioEngineering
TL;DR:
This paper demonstrates the utility of an unsupervised classification technique based on the Expectation-Maximization (EM) algorithm and naive Bayes classification that exhibits performance comparable to that of an analogous supervised learner constructed from the same training data.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: September 6, 2020
2006 chapter
Phosphoinositide Metabolism: Towards an Understanding of Subcellular Signaling
In A. L. Majumber & B. B. Biswas (Eds.), Biology of Inositols and Phosphoinositides (pp. 181–205).
Ed(s): A. Majumber & B. Biswas
MeSH headings : Animals; Humans; Multigene Family; Phosphatidylinositols / metabolism; Signal Transduction / genetics; Signal Transduction / physiology
TL;DR:
The goal is to convince the reader of the importance of characterizing the metabolic fluxes within the discrete subcellular phospholipid microdomains that make up the lipid signaling pools.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: March 7, 2021
2006 journal article
The N-terminal membrane occupation and recognition nexus domain of Arabidopsis phosphatidylinositol phosphate kinase 1 regulates enzyme activity
JOURNAL OF BIOLOGICAL CHEMISTRY, 282(8), 5443–5452.
MeSH headings : Amino Acid Motifs / genetics; Arabidopsis / enzymology; Arabidopsis / genetics; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Cell Membrane / enzymology; Cell Membrane / genetics; Escherichia coli / enzymology; Escherichia coli / genetics; Lipids / genetics; Minor Histocompatibility Antigens; Phosphotransferases (Alcohol Group Acceptor) / genetics; Phosphotransferases (Alcohol Group Acceptor) / metabolism; Protein Structure, Tertiary / genetics; Tobacco / enzymology; Tobacco / genetics
TL;DR:
It is concluded that the MORN peptide can regulate both the function and distribution of the enzyme in a manner that is sensitive to the lipid environment.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2005 journal article
A universal role for inositol 1,4,5-trisphosphate-mediated signaling in plant gravitropism
PLANT PHYSIOLOGY, 140(2), 746–760.
MeSH headings : Arabidopsis / anatomy & histology; Arabidopsis / genetics; Arabidopsis / growth & development; Genes, Reporter; Gravitropism / physiology; Humans; Hydrolysis; Indoleacetic Acids / metabolism; Inositol 1,4,5-Trisphosphate / metabolism; Inositol 1,4,5-Trisphosphate / physiology; Inositol Polyphosphate 5-Phosphatases; Molecular Sequence Data; Phosphoric Monoester Hydrolases / genetics; Phosphoric Monoester Hydrolases / metabolism; Plant Roots / growth & development; Plant Roots / metabolism; Plant Shoots / growth & development; Plant Shoots / metabolism; Plants, Genetically Modified / genetics; Plants, Genetically Modified / growth & development; Plants, Genetically Modified / metabolism; Signal Transduction
TL;DR:
The compromised gravitropic response in all the major axes of growth in the transgenic Arabidopsis plants reveals a universal role for InsP3 in the gravity signal transduction cascade of plants.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2005 journal article
Characterization and comparative analysis of Arabidopsis phosphatidylinositol phosphate 5-kinase 10 reveals differences in Arabidopsis and human phosphatidylinositol phosphate kinases
FEBS LETTERS, 579(16), 3427–3432.
author keywords: phosphatidylinositol phosphate kinase; lipid kinase; Arabidopsis
MeSH headings : Amino Acid Sequence; Arabidopsis / enzymology; Arabidopsis / genetics; Arabidopsis Proteins / chemistry; Arabidopsis Proteins / genetics; Arabidopsis Proteins / isolation & purification; Humans; Kinetics; Molecular Sequence Data; Phosphatidylinositol Phosphates / chemistry; Phosphotransferases (Alcohol Group Acceptor) / chemistry; Phosphotransferases (Alcohol Group Acceptor) / genetics; Phosphotransferases (Alcohol Group Acceptor) / isolation & purification; Phosphotransferases (Alcohol Group Acceptor) / metabolism; Sequence Alignment; Substrate Specificity; Transcription, Genetic
TL;DR:
Comparative analysis of recombinant AtPIPK10 and AtPipK1 with recombinant HsPIPKIα reveals that the Arabidopsis enzymes have roughly 200‐ and 20‐fold lower V max/K m, respectively, which reveal one explanation for the longstanding mystery of the relatively low phosphatidylinositol‐(4,5)‐bisphosphate:phosphatidic acid‐4‐ph phosphate ratio in terrestrial plants.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2004 journal article
Cyclodextrins enhance recombinant phosphatidylinositol phosphate kinase activity
JOURNAL OF LIPID RESEARCH, 45(9), 1783–1789.
author keywords: Arabidopsis thaliana; automated assay; inositol lipids
MeSH headings : Arabidopsis / enzymology; Arabidopsis / genetics; Cyclodextrins / pharmacology; Enzyme Activation / drug effects; Microsomes / drug effects; Microsomes / enzymology; Phosphotransferases (Alcohol Group Acceptor) / drug effects; Phosphotransferases (Alcohol Group Acceptor) / genetics; Phosphotransferases (Alcohol Group Acceptor) / metabolism; Recombinant Proteins / drug effects; Recombinant Proteins / genetics; Recombinant Proteins / metabolism
TL;DR:
It is shown that product can be recovered from the cyclodextrin-treated recombinant protein, which reveals a potential method for automating the assay for pharmacological screening, and a comparison of lipid kinase activity using substrate prepared in α, β, or γ-cyclodesxtrin indicated that β-cyclODExtrin was most effective and enhanced lipid Kinase activity 6-fold compared with substrate preparation in Triton X-100-mixed micelles.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2004 journal article
Differential Expression of Vacuolar H+-ATPase Subunit c Genes in Tissues Active in Membrane Trafficking and Their Roles in Plant Growth as Revealed by RNAi
Plant Physiology, 134(4), 1514–1526.
MeSH headings : Arabidopsis / enzymology; Arabidopsis / genetics; Arabidopsis / growth & development; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Base Sequence; Cotyledon / enzymology; Cotyledon / genetics; Cotyledon / growth & development; Flowers / enzymology; Flowers / genetics; Flowers / growth & development; Gene Expression Regulation, Enzymologic / drug effects; Gene Expression Regulation, Enzymologic / radiation effects; Gene Expression Regulation, Plant / drug effects; Gene Expression Regulation, Plant / radiation effects; Hypocotyl / enzymology; Hypocotyl / genetics; Hypocotyl / growth & development; Light; Membrane Transport Proteins / genetics; Membrane Transport Proteins / metabolism; Molecular Sequence Data; Mutation; Plant Root Cap / enzymology; Plant Root Cap / genetics; Plant Root Cap / growth & development; Pollen / enzymology; Pollen / genetics; Pollen / growth & development; Protein Subunits / genetics; Protein Subunits / metabolism; RNA Interference / physiology; Sequence Homology, Nucleic Acid; Signal Transduction / genetics; Signal Transduction / physiology; Sodium Chloride / pharmacology; Vacuolar Proton-Translocating ATPases / genetics; Vacuolar Proton-Translocating ATPases / metabolism
TL;DR:
Two VHA-c genes are differentially expressed to support growth in expanding cells and to supply increased demand for V-ATPase in cells with active exocytosis, suggesting a model for participation of the Vo sector and V1Vo-ATpase in membrane trafficking and fusion.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 6, 2020
2002 chapter
An Evolutionary Perspective of Phosphoinositide Signaling During Osmotic Stress
In V. Kravets (Ed.), Intracellular Signalling in Plant and Animal Systems.
Ed(s): V. Kravets
Source: NC State University Libraries
Added: April 1, 2021
2002 journal article
Up-regulation of phosphoinositide metabolism in tobacco cells constitutively expressing the human type I inositol polyphosphate 5-phosphatase
PLANT PHYSIOLOGY, 129(4), 1795–1806.
MeSH headings : Cells, Cultured; Gene Expression Regulation, Enzymologic; Humans; Inositol 1,4,5-Trisphosphate / metabolism; Inositol Polyphosphate 5-Phosphatases; Intercellular Signaling Peptides and Proteins; Peptides / metabolism; Phosphatidylinositol 4,5-Diphosphate / metabolism; Phosphatidylinositols / metabolism; Phosphoric Monoester Hydrolases / genetics; Phosphoric Monoester Hydrolases / metabolism; Phosphorus Radioisotopes; Plants, Genetically Modified; Tobacco / cytology; Tobacco / genetics; Tobacco / metabolism; Up-Regulation; Wasp Venoms / chemistry; Wasp Venoms / metabolism
TL;DR:
These studies show that the constitutive expression of the human type I InsP 5-ptase in tobacco cells leads to an up-regulation of the phosphoinositide pathway and highlight the importance of PtdInsP2 synthesis as a regulatory step in this system.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2001 journal article
A role for inositol 1,4,5-trisphosphate in gravitropic signaling and the retention of cold-perceived gravistimulation of oat shoot pulvini
PLANT PHYSIOLOGY, 125(3), 1499–1507.
MeSH headings : Avena / physiology; Cold Temperature; Enzyme Inhibitors / pharmacology; Estrenes / pharmacology; Gravitropism; Inositol 1,4,5-Trisphosphate / physiology; Plant Shoots / physiology; Pyrrolidinones / pharmacology; Signal Transduction / physiology; Type C Phospholipases / antagonists & inhibitors
TL;DR:
It is proposed that inositol 1,4,5-trisphosphate (InsP(3) may be involved in the retention of cold-perceived gravistimulation by providing positional information in the pulvini prior to the redistribution of auxin.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2001 conference paper
Altering phosphoinositide metabolism by expressing human type I inositol polyphosphate 5 ' phosphatase in tobacco cells
Molecular Biology of the Cell, 12(2001 Nov), 820.
Source: NC State University Libraries
Added: August 6, 2018
2001 journal article
Plasma membrane phosphatidylinositol 4,5-bisphosphate levels decrease with time in culture
PLANT PHYSIOLOGY, 126(4), 1507–1518.
MeSH headings : Blotting, Western; Cell Membrane / metabolism; Cells, Cultured; Inositol 1,4,5-Trisphosphate / metabolism; Microsomes / metabolism; Minor Histocompatibility Antigens; Osmotic Pressure; Phosphatidylinositol 4,5-Diphosphate / metabolism; Phospholipids / analysis; Phosphotransferases (Alcohol Group Acceptor) / metabolism; Rhodophyta / metabolism; Signal Transduction; Time
TL;DR:
During the stationary phase of growth, after 7 to 12 d in culture, the levels of phosphatidylinositol 4,5-bisphosphate (PtdInsP(2) decreased by 75% in plasma membranes of the red alga Galdieria sulphuraria, and there was an increase in PTDInsP (2) in microsomes, suggesting that the levels that are regulated differentially.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2001 journal article
Transient dissociation of polyribosomes and concurrent recruitment of calreticulin and calmodulin transcripts in gravistimulated maize pulvini
PLANT PHYSIOLOGY, 127(3), 1193–1203.
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2000 journal article
Inositol signaling and plant growth
Trends in Plant Science, 5(6), 252–258.
MeSH headings : Inositol / metabolism; Inositol 1,4,5-Trisphosphate / metabolism; Inositol Phosphates / metabolism; Phosphatidylinositols / metabolism; Plant Development; Signal Transduction; Stereoisomerism
TL;DR:
The stereospecificity of the six hydroxyls on the inositol ring provides the basis for the functional diversity of the phosphorylated isomers that generate a selective means of intracellular and intercellular communication for coordinating cell growth.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018
1999 journal article
Changes in phosphoinositide metabolism with days in culture affect signal transduction pathways in Galdieria sulphuraria
PLANT PHYSIOLOGY, 119(4), 1331–1339.
TL;DR:
The increase in PIP kinase activity before IP3 signaling in d-12 cells indicates that there is an additional pathway for regulation of phosphoinositide metabolism after stimulation other than an initial activation of phospholipase C.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
1999 journal article
Transient and sustained increases in inositol 1,4,5-hisphosphate precede the differential growth response in gravistimulated maize pulvini
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 96(10), 5838–5843.
MeSH headings : Cell Membrane / metabolism; Cell Size; Gravitation; Inositol 1,4,5-Trisphosphate / metabolism; Inositol Polyphosphate 5-Phosphatases; Phosphatidylinositol 4,5-Diphosphate / metabolism; Phosphoric Monoester Hydrolases / metabolism; Phosphotransferases (Alcohol Group Acceptor) / metabolism; Pulvinus / growth & development; Second Messenger Systems; Time Factors; Zea mays / metabolism
TL;DR:
The data indicate the involvement of IP3 and inositol phospholipids in both short- and long-term responses to gravistimulation, as a diffusible second messenger providing a mechanism to transmit and amplify the signal from the perceiving to the responding cells in the pulvinus, coordinating a synchronized growth response.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
1998 journal article
A phosphatidylinositol 4-kinase pleckstrin homology domain that binds phosphatidylinositol 4-monophosphate
JOURNAL OF BIOLOGICAL CHEMISTRY, 273(35), 22761–22767.
MeSH headings : 1-Phosphatidylinositol 4-Kinase / chemistry; 1-Phosphatidylinositol 4-Kinase / genetics; 1-Phosphatidylinositol 4-Kinase / metabolism; Amino Acid Sequence; Animals; Arabidopsis / enzymology; Base Sequence; Blood Proteins / genetics; Blood Proteins / metabolism; Blotting, Western; Cells, Cultured; Cloning, Molecular; Daucus carota / enzymology; Humans; Molecular Sequence Data; Molecular Weight; Phosphatidylinositol Phosphates / metabolism; Phosphoproteins; Protein Binding; Rats; Recombinant Proteins / metabolism; Sequence Homology, Amino Acid
TL;DR:
The recombinant PI 4-kinase PH domain was explored for its ability to bind to different phospholipids and had the highest affinity for PI-4-P, the product of the reaction.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
1998 chapter
Inositol lipid signaling: what can we learn from plants?
In E. C.-O. J. Sanchez & E. Martinez-Force (Eds.), Advances in lipids research (pp. 394–397). Sevilla, Spain: University of Sevilla Press.
Ed(s): E. J. Sanchez & E. Martinez-Force
Source: NC State University Libraries
Added: August 6, 2018
1996 chapter
Signal transduction pathways: a plant perspective of inositol metabolism and growth
In W. R. Briggs, R. L. Heath, & E. M. Tobin (Eds.), Regulation of plant growth and development by light development (pp. 114–126). Rockville, MD: American Society of Plant Physiologists.
Ed(s): W. Briggs, R. Heath & E. Tobin
Source: NC State University Libraries
Added: April 1, 2021
1995 journal article
Several distinct genes encode nearly identical 16 kDa proteolipids of the vacuolar H+-ATPase from Arabidopsis thaliana
Plant Molecular Biology, 29(2), 227–244.
author keywords: VACUOLAR-TYPE; H+-PUMPING ATPASE; 16 KDA SUBUNIT; PROTEOLIPID; ARABIDOPSIS THALIANA; MULTIGENE FAMILY
MeSH headings : Adaptation, Biological; Amino Acid Sequence; Arabidopsis / enzymology; Arabidopsis / genetics; Arabidopsis / radiation effects; Base Sequence; Blotting, Northern; Blotting, Southern; DNA, Complementary / genetics; Gene Expression; Gene Library; Genes, Plant; Genome, Plant; Light; Molecular Sequence Data; Multigene Family; Protein Conformation; Proteolipids / genetics; Proton-Translocating ATPases / genetics; Restriction Mapping; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Species Specificity; Tissue Distribution; Vacuoles / enzymology
TL;DR:
Arabidopsis thaliana, there-fore, has at least four distinct genes encoding nearly identical 16 kDa proteolipids, and the enhanced expression of AVA-P2 transcript in etiolated seedlings suggests that an increase in V-ATPase could accompany cell expansion.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: March 7, 2021
1993 journal article
Calmodulin isoforms in Arabidopsis encoded by multiple divergent mRNAs
Plant Molecular Biology, 22(2), 215–225.
author keywords: ARABIDOPSIS; CALMODULIN SEQUENCE; GENE EXPRESSION
MeSH headings : Amino Acid Sequence; Arabidopsis / genetics; Base Sequence; Calmodulin / genetics; Genes, Plant / genetics; Genetic Variation; Genome; Molecular Sequence Data; Multigene Family / genetics; RNA, Messenger / biosynthesis; RNA, Messenger / genetics; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid
TL;DR:
The results suggest that CaM isoforms in Arabidopsis may have evolved to optimize the interaction of this Ca2+-receptor protein with specific subsets of response elements.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 6, 2020
1992 journal article
Structure and expression of the Arabidopsis CaM-3 calmodulin gene
Plant Molecular Biology, 19(4), 649–664.
author keywords: ARABIDOPSIS CALMODULIN SEQUENCE; GENE REGULATION; TRANSCRIPTION
MeSH headings : Amino Acid Sequence; Base Sequence; Calmodulin / genetics; Calmodulin / metabolism; DNA; Gene Expression Regulation; Handling, Psychological; Introns; Molecular Sequence Data; Nucleic Acid Hybridization; Plants / genetics; Polymerase Chain Reaction; Promoter Regions, Genetic; RNA, Messenger / metabolism; Restriction Mapping; Sequence Homology, Nucleic Acid; Transcription, Genetic
TL;DR:
Run-on transcription assays indicated that a portion of the differences in accumulation of ACaM-1, 2, and 3 mRNAs in leaves and siliques was attributable to differences in their net rates of transcription.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 6, 2020
1992 journal article
Synthesis and Accumulation of Calmodulin in Suspension Cultures of Carrot (Daucus carota L.)
Plant Physiology, 100(2), 812–819.
TL;DR:
The expression of calmodulin mRNA and protein were measured during a growth cycle of carrot cells grown in suspension culture and the qualitative spectrum of polypeptides synthesized and accumulated by the carrot cells during the course of a culture cycle remained largely unchanged.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: April 1, 2021
1992 journal article
Vacuolar-type H+-translocating ATPases in plant endomembranes: subunit organization and multigene families
Journal of Experimental Biology, 172, 123–135.
Source: NC State University Libraries
Added: April 1, 2021
1991 journal article
Primary Structures of Arabidopsis Calmodulin Isoforms Deduced from the Sequences of cDNA Clones
Plant Physiology, 96(4), 1196–1202.
TL;DR:
Northern blot and polymerase chain reaction assays both indicate that ACaM-1 mRNA is more highly expressed than ACam-2 mRNA in developing siliques in developing Siliques, and the steady-state levels of both isoform mRNAs increase as a result of touch stimulation; the kinetics and extent of increase are comparable for the two m RNAs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: March 7, 2021
Employment
Updated: January 15th, 2020 19:11
North Carolina State University Raleigh, NC, US
Research Professor
Plant and Microbial Biology
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