Works (66)

Updated: July 15th, 2024 05:22

2024 article

Overcoming the effects of fluid shear stress in ovarian cancer cell lines: Doxorubicin alone or photodynamic priming to target platinum resistance

Overchuk, M., Rickard, B. P., Tulino, J., Tan, X., Ligler, F. S., Huang, H.-C., & Rizvi, I. (2024, June 7). PHOTOCHEMISTRY AND PHOTOBIOLOGY, Vol. 6.

By: M. Overchuk n, B. Rickard*, J. Tulino n, X. Tan*, F. Ligler*, H. Huang*, I. Rizvi n

author keywords: benzoporphyrin derivative; cisplatin; doxorubicin; high-grade serous ovarian carcinoma; ovarian cancer; photodynamic priming
UN Sustainable Development Goal Categories
1. No Poverty (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: June 17, 2024

2023 journal article

Development of a light emitting device for the treatment of peritoneal car- cinomatosis of ovarian origin by intracavitary photodynamic therapy

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 41.

By: M. Overchuk, M. Ruhi, B. Rickard, F. Ligler & I. Rizvi

author keywords: Photodynamic therapy; peritoneal carcinomatosis; ovarian cancer
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: May 22, 2023

2023 journal article

Exposure to select PFAS and PFAS mixtures alters response to platinum-based chemotherapy in endometrial cancer cell lines

ENVIRONMENTAL HEALTH, 22(1).

By: B. Rickard*, M. Overchuk n, J. Tulino n, X. Tan, F. Ligler*, V. Bae-Jump*, S. Fenton*, I. Rizvi n

author keywords: PFAS; Endometrial cancer; Therapy resistance; Carboplatin; Cisplatin; Mitochondria
TL;DR: Investigation of the effect of environmental exposures, specifically PFAS, on platinum-based chemotherapy response and mitochondrial function in endometrial cancer suggests that PFAS exposure may affect endometrial cancer cell mitochondrial functioning. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: January 2, 2024

2023 review

Methods to Evaluate Changes in Mitochondrial Structure and Function in Cancer

[Review of ]. CANCERS, 15(9).

By: B. Rickard*, M. Overchuk n, V. Chappell*, M. Kemal Ruhi*, P. Sinawang*, T. Nguyen Hoang*, D. Akin*, U. Demirci ...

author keywords: mitochondrial methods; bioenergetics; mitochondrial dysfunction; reactive species; mitochondrial function; mitochondrial structure; extracellular vesicles
TL;DR: Methods to evaluate the structural and functional parameters of mitochondrial health in the context of tumors and cancer cells are discussed, with a particular emphasis on gynecologic malignancies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: May 30, 2023

2023 journal article

Photodynamic Priming Overcomes Per‐ and Polyfluoroalkyl Substance (PFAS)‐Induced Platinum Resistance in Ovarian Cancer†

Photochemistry and Photobiology.

By: B. Rickard, X. Tan, S. Fenton & I. Rizvi

Source: ORCID
Added: July 15, 2024

2023 journal article

Targeted PDT Combinations to Overcome Fluid Shear Stress-induced Plat- inum Resistance in Ovarian Cancer

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 41.

By: M. Overchuk n, M. Ruhi n, B. Rickard n, F. Ligler* & I. Rizvi n

author keywords: photodynamic therapy; ovarian cancer; benzoporphyrin derivative; chemoresistance; shear stress
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: May 22, 2023

2023 journal article

Transient fluid flow improves photoimmunoconjugate delivery and photoimmunotherapy efficacy

ISCIENCE, 26(8).

By: A. Sorrin*, K. Zhou*, K. May*, C. Liu*, K. McNaughton*, I. Rahman*, B. Liang*, I. Rizvi n, D. Roque*, H. Huang*

TL;DR: The fundamental role of fluid flow-induced shear stress in the anti-cancer effects of photoimmunotherapy is confirmed and enhanced phototoxicity compared to static conditions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 28, 2023

2022 journal article

Critical PDT theory II: Current concepts and indications

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 39.

By: D. Kessel*, G. Obaid* & I. Rizvi n

author keywords: Photodynamic therapy; Apoptosis; Photosensitization
MeSH headings : Humans; Neoplasms / drug therapy; Neoplasms / pathology; Photochemotherapy / methods; Photosensitizing Agents / therapeutic use
TL;DR: Current research efforts that improve clinical relevance and those that do not are provided, including those that describe phenomena that only reiterate what is already known. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 8, 2022

2022 journal article

Mechanical Modulation of Ovarian Cancer Tumor Nodules Under Flow

IEEE Transactions on Biomedical Engineering, 69(1), 294–301.

By: C. Conrad, K. Moore, W. Polacheck, I. Rizvi & G. Scarcelli

Source: ORCID
Added: July 15, 2024

2022 journal article

Per- and poly-fluoroalkyl substances (PFAS) and female reproductive outcomes: PFAS elimination, endocrine-mediated effects, and disease

TOXICOLOGY, 465.

By: B. Rickard n, I. Rizvi n & S. Fenton*

author keywords: PFAS; Female reproduction; Environmental contaminants; Endocrine disruption
MeSH headings : Endocrine Disruptors / adverse effects; Endocrine System Diseases / chemically induced; Endocrine System Diseases / metabolism; Endocrine System Diseases / physiopathology; Environmental Exposure / adverse effects; Environmental Pollutants / adverse effects; Female; Fertility / drug effects; Humans; Hydrocarbons, Fluorinated / adverse effects; Infertility, Female / chemically induced; Infertility, Female / metabolism; Infertility, Female / physiopathology; Menstrual Cycle / drug effects; Pregnancy; Pregnancy Complications / chemically induced; Pregnancy Complications / metabolism; Pregnancy Complications / physiopathology; Prognosis; Reproduction / drug effects; Risk Assessment; Risk Factors
TL;DR: The role of a variety of PFAS and PFAS mixtures in female reproductive tract dysfunction and disease is summarized and the role ofPFAS in breast, thyroid, and hypothalamic-pituitary-gonadal axis function is discussed as the interplay between these tissues may be critical in understanding the long-term reproductive health effects of PFas in women. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: November 29, 2021

2022 article

Photochemical Targeting of Mitochondria to Overcome Chemoresistance in Ovarian Cancer

Rickard, B. P., Overchuk, M., Obaid, G., Ruhi, M. K., Demirci, U., Fenton, S. E., … Rizvi, I. (2022, October 19). PHOTOCHEMISTRY AND PHOTOBIOLOGY, Vol. 10.

UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: October 31, 2022

2022 article

Photodynamic Stromal Depletion Enhances Therapeutic Nanoparticle Delivery in 3D Pancreatic Ductal Adenocarcinoma Tumor Models

Karimnia, V., Stanley, M. E., Fitzgerald, C. T., Rizvi, I., Slack, F. J., & Celli, J. P. (2022, August 3). PHOTOCHEMISTRY AND PHOTOBIOLOGY, Vol. 8.

By: V. Karimnia, M. Stanley n, C. Fitzgerald n, I. Rizvi n, F. Slack* & J. Celli

MeSH headings : Humans; Pancreatic Neoplasms / drug therapy; Carcinoma, Pancreatic Ductal / drug therapy; Nanoparticles; MicroRNAs / genetics; Cell Line, Tumor; RNA-Binding Proteins; Apoptosis Regulatory Proteins / metabolism; Apoptosis Regulatory Proteins / therapeutic use
TL;DR: Results in 3D tumor models suggest that PSD could be developed to enhance delivery of other cancer therapeutics and improve tumor response to treatment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: August 29, 2022

2022 journal article

Select Per- and Polyfluoroalkyl Substances (PFAS) Induce Resistance to Carboplatin in Ovarian Cancer Cell Lines

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(9).

By: B. Rickard*, X. Tan*, S. Fenton* & I. Rizvi n

author keywords: per- and polyfluoroalkyl substances; PFAS; ovarian cancer; platinum resistance; carboplatin; mitochondrial function
MeSH headings : Alkanesulfonic Acids / toxicity; Carboplatin / pharmacology; Carcinoma, Ovarian Epithelial; Cell Line; Environmental Pollutants / toxicity; Female; Fluorocarbons / toxicity; Humans; Ovarian Neoplasms / drug therapy
TL;DR: This is the first study to demonstrate that, at sub-cytotoxic concentrations, select PFAS and PFAS mixtures increased survival fraction in ovarian cancer cells following carboplatin treatment, indicative of platinum resistance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: May 23, 2022

2022 journal article

Water transport regulates nucleus volume, cell density, Young's modulus, and E-cadherin expression in tumor spheroids.

European Journal of Cell Biology.

By: C. Conrad, J. Conway, W. Polacheck, I. Rizvi & G. Scarcelli

Source: ORCID
Added: July 15, 2024

2021 journal article

Emerging biofabrication approaches for gastrointestinal organoids towards patient specific cancer models

CANCER LETTERS, 504, 116–124.

author keywords: Bioengineering; Organ on a chip; Self-assembly; Externally driven assembly; Personalized medicine
MeSH headings : Cell Differentiation; Gastrointestinal Tract / cytology; Humans; Models, Biological; Organoids / cytology; Precision Medicine; Tissue Engineering / methods
TL;DR: Development in three-dimensional (3D) artificial cell constructs to model gastrointestinal dynamics towards cancer diagnosis and the main challenges and possible risks regarding the potential translation of gastrointestinal organoids from laboratory settings to patient-specific models in clinical applications are outlined. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: April 5, 2021

2021 review

Malignant Ascites in Ovarian Cancer: Cellular, Acellular, and Biophysical Determinants of Molecular Characteristics and Therapy Response

[Review of ]. CANCERS, 13(17).

By: B. Rickard n, C. Conrad*, A. Sorrin*, M. Ruhi n, J. Reader*, S. Huang n, W. Franco*, G. Scarcelli* ...

author keywords: malignant ascites; epithelial ovarian cancer; chemoresistance; mechanical stress; flow-induced shear stress; photodynamic therapy; tumor microenvironment; transcoelomic metastases; tumor heterogeneity; epithelial to mesenchymal transition
TL;DR: The current understanding of malignant ascites is summarized, starting with an overview of ovarian cancer and ascites, followed by a description of the tools used to analyze the components of ascites and how these components modulate ovarian cancer biology. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: September 20, 2021

2021 journal article

Photodestruction of Stromal Fibroblasts Enhances Tumor Response to PDT in 3D Pancreatic Cancer Coculture Models

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 97(2), 416–426.

By: V. Karimnia*, I. Rizvi n, F. Slack* & J. Celli*

MeSH headings : Carcinoma, Pancreatic Ductal / drug therapy; Carcinoma, Pancreatic Ductal / pathology; Cell Line, Tumor; Coculture Techniques; Fibroblasts / pathology; Humans; Pancreatic Neoplasms / drug therapy; Pancreatic Neoplasms / pathology; Photochemotherapy; Stromal Cells / pathology
TL;DR: The results point to the potential for PDT to overcome tumor‐promoting stromal interactions associated with poor therapeutic response in PDAC, and increase response to PDT relative to homotypic cultures. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: November 16, 2020

2020 journal article

Cabozantinib Inhibits Photodynamic Therapy-Induced Auto- and Paracrine MET Signaling in Heterotypic Pancreatic Microtumors

Cancers.

By: M. Broekgaarden, A. Alkhateeb, S. Bano, A. Bulin, G. Obaid, I. Rizvi, T. Hasan

Source: ORCID
Added: July 15, 2024

2020 journal article

Cancer Cell‐targeted and Activatable Photoimmunotherapy Spares T Cells in a 3D Coculture Model

Photochemistry and Photobiology.

By: E. Kercher, S. Nath, I. Rizvi & B. Spring

Source: ORCID
Added: July 15, 2024

2020 journal article

Flow-induced Shear Stress Confers Resistance to Carboplatin in an Adherent Three-Dimensional Model for Ovarian Cancer: A Role for EGFR-Targeted Photoimmunotherapy Informed by Physical Stress

Journal of Clinical Medicine.

By: S. Nath, M. Pigula, A. Khan, W. Hanna, M. Ruhi, F. Dehkordy, K. Pushpavanam, K. Rege ...

Source: ORCID
Added: July 15, 2024

2020 journal article

Photodynamic Therapy and the Biophysics of the Tumor Microenvironment

Photochemistry and Photobiology.

By: A. Sorrin, M. Ruhi, N. Ferlic, V. Karimnia, W. Polacheck, J. Celli, H. Huang, I. Rizvi

Source: ORCID
Added: July 15, 2024

2020 journal article

Vitamin D Receptor Activation and Photodynamic Priming Enables Durable Low-dose Chemotherapy

MOLECULAR CANCER THERAPEUTICS, 19(6), 1308–1319.

By: S. Anbil*, M. Pigula*, H. Huang*, S. Mallidi*, M. Broekgaarden*, Y. Baglo*, P. De Silva*, D. Simeone* ...

MeSH headings : Animals; Antineoplastic Agents / pharmacology; Apoptosis; Biomarkers, Tumor / genetics; Biomarkers, Tumor / metabolism; Calcitriol / analogs & derivatives; Calcitriol / pharmacology; Carcinoma, Pancreatic Ductal / drug therapy; Carcinoma, Pancreatic Ductal / metabolism; Carcinoma, Pancreatic Ductal / pathology; Carcinoma, Pancreatic Ductal / radiotherapy; Cell Proliferation; Chemokine CXCL12 / genetics; Chemokine CXCL12 / metabolism; Dermatologic Agents / pharmacology; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Nude; Pancreatic Neoplasms / drug therapy; Pancreatic Neoplasms / metabolism; Pancreatic Neoplasms / pathology; Pancreatic Neoplasms / radiotherapy; Photochemotherapy; Receptors, CXCR / genetics; Receptors, CXCR / metabolism; Receptors, CXCR4 / genetics; Receptors, CXCR4 / metabolism; Receptors, Calcitriol / genetics; Receptors, Calcitriol / metabolism; Tumor Cells, Cultured; Xenograft Model Antitumor Assays
TL;DR: A dual pronged approach to modulate the microenvironment of desmoplastic pancreatic tumors and enable significant dose deescalation of the FDA-approved chemotherapeutic nanoliposomal irinotecan (nal-IRI) without compromising tumor control is introduced. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: June 22, 2020

2019 journal article

A Combination of Visudyne and a Lipid‐anchored Liposomal Formulation of Benzoporphyrin Derivative Enhances Photodynamic Therapy Efficacy in a 3D Model for Ovarian Cancer

Photochemistry and Photobiology.

By: I. Rizvi, S. Nath, G. Obaid, M. Ruhi, K. Moore, S. Bano, D. Kessel, T. Hasan

Source: ORCID
Added: July 15, 2024

2019 journal article

Illuminating the Numbers: Integrating Mathematical Models to Optimize Photomedicine Dosimetry and Combination Therapies

FRONTIERS IN PHYSICS, 7.

author keywords: photomedicine; mathematical oncology; photodynamic therapy; immunotherapy; computational modeling; combination therapy; cancer
TL;DR: The utility of mathematical and computational approaches to guide adaptive therapy, and how mathematical models might be further developed and integrated as a novel methodology to guide precision photomedicine are foreseen. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: April 15, 2019

2019 journal article

Mechanical Characterization of 3D Ovarian Cancer Nodules Using Brillouin Confocal Microscopy

CELLULAR AND MOLECULAR BIOENGINEERING, 12(3), 215–226.

By: C. Conrad*, K. Gray*, K. Stroka*, I. Rizvi n & G. Scarcelli*

author keywords: Tumors; Osmolality; Young's modulus; Stiffness; Spheroids; Optics; Atomic force microscopy; MicroSquisher
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: July 15, 2019

2018 journal article

Neoadjuvant photodynamic therapy augments immediate and prolonged oxaliplatin efficacy in metastatic pancreatic cancer organoids.

Oncotarget.

By: M. Broekgaarden, I. Rizvi, A. Bulin, L. Petrovic, R. Goldschmidt, I. Massodi, J. Celli, T. Hasan

Source: ORCID
Added: July 15, 2024

2018 journal article

Photodynamic therapy: Promoting in vitro efficacy of photodynamic therapy by liposomal formulations of a photosensitizing agent.

Lasers in Surgery and Medicine.

By: I. Rizvi, G. Obaid, S. Bano, T. Hasan & D. Kessel

Source: ORCID
Added: July 15, 2024

2017 journal article

Mechanism-informed Repurposing of Minocycline Overcomes Resistance to Topoisomerase Inhibition for Peritoneal Carcinomatosis.

Molecular Cancer Therapeutics.

By: H. Huang, J. Liu, Y. Baglo, I. Rizvi, S. Anbil, M. Pigula, T. Hasan

Source: ORCID
Added: July 15, 2024

2017 journal article

Photodynamic Priming Mitigates Chemotherapeutic Selection Pressures and Improves Drug Delivery.

Cancer Research.

By: H. Huang, I. Rizvi, J. Liu, S. Anbil, A. Kalra, H. Lee, Y. Baglo, N. Paz ...

Source: ORCID
Added: July 15, 2024

2015 journal article

In vivo evaluation of battery-operated light-emitting diode-based photodynamic therapy efficacy using tumor volume and biomarker expression as endpoints.

Journal of Biomedical Optics.

By: S. Mallidi, Z. Mai, I. Rizvi, J. Hempstead, S. Arnason, J. Celli, T. Hasan

Source: ORCID
Added: July 15, 2024

2015 journal article

Low-cost photodynamic therapy devices for global health settings: Characterization of battery-powered LED performance and smartphone imaging in 3D tumor models.

Scientific Reports.

By: J. Hempstead, D. Jones, A. Ziouche, G. Cramer, I. Rizvi, S. Arnason, T. Hasan, J. Celli

Source: ORCID
Added: July 15, 2024

2015 journal article

Photodynamic Therapy Synergizes with Irinotecan to Overcome Compensatory Mechanisms and Improve Treatment Outcomes in Pancreatic Cancer.

Cancer Research.

By: H. Huang, S. Mallidi, J. Liu, C. Chiang, Z. Mai, R. Goldschmidt, N. Ebrahim-Zadeh, I. Rizvi, T. Hasan

Source: ORCID
Added: July 15, 2024

2015 journal article

The role of photodynamic therapy in overcoming cancer drug resistance.

Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology.

By: B. Spring, I. Rizvi, N. Xu & T. Hasan

Source: ORCID
Added: July 15, 2024

2014 journal article

"Pointsource" delivery of a photosensitizer drug and singlet oxygen: eradication of glioma cells in vitro.

Photochemistry and Photobiology.

By: A. Ghogare, I. Rizvi, T. Hasan & A. Greer

Source: ORCID
Added: July 15, 2024

2014 journal article

An imaging-based platform for high-content, quantitative evaluation of therapeutic response in 3D tumour models.

Scientific Reports.

By: J. Celli, I. Rizvi, A. Blanden, I. Massodi, B. Pogue & T. Hasan

Source: ORCID
Added: July 15, 2024

2014 journal article

Selective treatment and monitoring of disseminated cancer micrometastases in vivo using dual-function, activatable immunoconjugates.

Proceedings of the National Academy of Sciences of the United States of America.

By: B. Spring, A. Abu-Yousif, A. Palanisami, I. Rizvi, X. Zheng, Z. Mai, S. Anbil, R. Sears ...

Source: ORCID
Added: July 15, 2024

2013 journal article

Flow induces epithelial-mesenchymal transition, cellular heterogeneity and biomarker modulation in 3D ovarian cancer nodules.

Proceedings of the National Academy of Sciences of the United States of America, 110(22), E1974–E1983.

By: I. Rizvi, U. Gurkan, S. Tasoglu, N. Alagic, J. Celli, L. Mensah, Z. Mai, U. Demirci, T. Hasan

Contributors: I. Rizvi, U. Gurkan, S. Tasoglu, N. Alagic, J. Celli, L. Mensah, Z. Mai, U. Demirci, T. Hasan

Source: ORCID
Added: July 15, 2024

2013 journal article

Impact of treatment response metrics on photodynamic therapy planning and outcomes in a three-dimensional model of ovarian cancer

Journal of Biomedical Optics, 18(9), 098004.

By: S. Anbil, I. Rizvi, J. Celli, N. Alagic, B. Pogue & T. Hasan

Source: ORCID
Added: July 15, 2024

2013 journal article

PDT dose parameters impact tumoricidal durability and cell death pathways in a 3D ovarian cancer model.

Photochemistry and Photobiology, 89(4), 942–952.

By: I. Rizvi, S. Anbil, N. Alagic, J. Celli, L. Zheng, A. Palanisami, M. Glidden, B. Pogue, T. Hasan

Contributors: I. Rizvi, S. Anbil, N. Alagic, J. Celli, L. Zheng, A. Palanisami, M. Glidden, B. Pogue, T. Hasan

Source: ORCID
Added: July 15, 2024

2012 journal article

Image-Based Quantification of Benzoporphyrin Derivative Uptake, Localization, and Photobleaching in 3D Tumor Models, for Optimization of PDT Parameters

Theranostics, 2(9), 827–839.

By: M. Glidden, J. Celli, I. Massodi, I. Rizvi, B. Pogue & T. Hasan

Contributors: M. Glidden, J. Celli, I. Massodi, I. Rizvi, B. Pogue & T. Hasan

Source: ORCID
Added: July 15, 2024

2012 journal article

Photoimmunotherapy and Irradiance Modulation Reduce Chemotherapy Cycles and Toxicity in a Murine Model for Ovarian Carcinomatosis: Perspective and Results

Israel Journal of Chemistry, 52(8-9), 776–787.

By: I. Rizvi, T. Dinh, W. Yu, Y. Chang, M. Sherwood & T. Hasan

Source: ORCID
Added: July 15, 2024

2011 journal article

A three-dimensional in vitro ovarian cancer coculture model using a high-throughput cell patterning platform.

Biotechnology Journal, 6(2), 204–212.

By: F. Xu, J. Celli, I. Rizvi, S. Moon, T. Hasan & U. Demirci

Contributors: F. Xu, J. Celli, I. Rizvi, S. Moon, T. Hasan & U. Demirci

Source: ORCID
Added: July 15, 2024

2011 journal article

Killing hypoxic cell populations in a 3D tumor model with EtNBS-PDT.

PloS One, 6(8).

By: C. Evans, A. Abu-Yousif, Y. Park, O. Klein, J. Celli, I. Rizvi, X. Zheng, T. Hasan

Contributors: C. Evans, A. Abu-Yousif, Y. Park, O. Klein, J. Celli, I. Rizvi, X. Zheng, T. Hasan

Source: ORCID
Added: July 15, 2024

2010 journal article

Imaging Tumor Variation in Response to Photodynamic Therapy in Pancreatic Cancer Xenograft Models

International Journal of Radiation Oncology Biology Physics, 76(1), 251–259.

By: K. Samkoe, A. Chen, I. Rizvi, J. OHara, P. Hoopes, S. Pereira, T. Hasan, B. Pogue

Contributors: K. Samkoe, A. Chen, I. Rizvi, J. O'Hara, P. Hoopes, S. Pereira, T. Hasan, B. Pogue

Source: ORCID
Added: July 15, 2024

2010 journal article

Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization

Chemical Reviews, 110(5), 2795–2838.

By: J. Celli, B. Spring, I. Rizvi, C. Evans, K. Samkoe, S. Verma, B. Pogue, T. Hasan

Contributors: J. Celli, B. Spring, I. Rizvi, C. Evans, K. Samkoe, S. Verma, B. Pogue, T. Hasan

Source: ORCID
Added: July 15, 2024

2010 journal article

Ki-67 as a Molecular Target for Therapy in an In vitro Three-Dimensional Model for Ovarian Cancer

Cancer Research, 70(22), 9234–9242.

By: R. Rahmanzadeh, P. Rai, J. Celli, I. Rizvi, B. Baron-Luehr, J. Gerdes, T. Hasan

Contributors: R. Rahmanzadeh, P. Rai, J. Celli, I. Rizvi, B. Baron-Luehr, J. Gerdes, T. Hasan

Source: ORCID
Added: July 15, 2024

2010 journal article

Quantitative imaging reveals heterogeneous growth dynamics and treatment-dependent residual tumor distributions in a three-dimensional ovarian cancer model

Journal of Biomedical Optics, 15(5).

By: J. Celli, I. Rizvi, C. Evans, A. Abu-Yousif & T. Hasan

Contributors: J. Celli, I. Rizvi, C. Evans, A. Abu-Yousif & T. Hasan

Source: ORCID
Added: July 15, 2024

2010 journal article

Synergistic Enhancement of Carboplatin Efficacy with Photodynamic Therapy in a Three-Dimensional Model for Micrometastatic Ovarian Cancer

Cancer Research, 70(22), 9319–9328.

By: I. Rizvi, J. Celli, C. Evans, A. Abu-Yousif, A. Muzikansky, B. Pogue, D. Finkelstein, T. Hasan

Contributors: I. Rizvi, J. Celli, C. Evans, A. Abu-Yousif, A. Muzikansky, B. Pogue, D. Finkelstein, T. Hasan

Source: ORCID
Added: July 15, 2024

2009 journal article

In vitro ovarian tumor growth and treatment response dynamics visualized with time-lapse OCT imaging

Optics Express, 17(11), 8892–8906.

By: C. Evans, I. Rizvi, T. Hasan & J. Boer

Contributors: C. Evans, I. Rizvi, T. Hasan & J. Boer

Source: ORCID
Added: July 15, 2024

2009 journal article

In vivo high-resolution fluorescence microendoscopy for ovarian cancer detection and treatment monitoring

British Journal of Cancer, 101, 2015–2022. 10.1038/sj.bjc.6605436. Epub 2009 Nov 17.

By: W. Zhong, J. Celli, I. Rizvi, Z. Mai, B. Spring, S. Yun, T. Hasan

Contributors: W. Zhong, J. Celli, I. Rizvi, Z. Mai, B. Spring, S. Yun, T. Hasan

Source: ORCID
Added: July 15, 2024

2009 journal article

PuraMatrix encapsulation of cancer cells

Journal of Visualized Experiments : JoVE, (34).

By: A. Abu-Yousif, I. Rizvi, C. Evans, J. Celli & T. Hasan

Contributors: A. Abu-Yousif, I. Rizvi, C. Evans, J. Celli & T. Hasan

Source: ORCID
Added: July 15, 2024

2008 journal article

In vivo optical molecular imaging of vascular endothelial growth factor for monitoring cancer treatment

Clinical Cancer Research, 14(13), 4146–4153.

By: S. Chang, I. Rizvi, N. Solban & T. Hasan

Contributors: S. Chang, I. Rizvi, N. Solban & T. Hasan

Source: ORCID
Added: July 15, 2024

2008 journal article

In-vivo singlet oxygen dosimetry of clinical 5-aminolevulinic acid photodynamic therapy

Journal of Biomedical Optics, 13(5).

By: H. Laubach, S. Chang, S. Lee, I. Rizvi, D. Zurakowski, S. Davis, C. Taylor, T. Hasan

Contributors: H. Laubach, S. Chang, S. Lee, I. Rizvi, D. Zurakowski, S. Davis, C. Taylor, T. Hasan

Source: ORCID
Added: July 15, 2024

2006 journal article

A mechanism-based combination therapy reduces local tumor growth and metastasis in an orthotopic model of prostate cancer

Cancer Research, 66(22), 10953–10958.

By: B. Kosharskyy, N. Solban, S. Chang, I. Rizvi, Y. Chang & T. Hasan

Contributors: B. Kosharskyy, N. Solban, S. Chang, I. Rizvi, Y. Chang & T. Hasan

Source: ORCID
Added: July 15, 2024

2006 conference paper

In vivo Imaging of VEGF Expression for Monitoring Molecular Response to Cancer Therapy

Biomedical Optics, TuC4.

By: S. Chang, I. Rizvi, N. Solban & T. Hasan

Source: ORCID
Added: July 15, 2024

2006 journal article

Targeted photodynamic therapy

Lasers in Surgery and Medicine, 38(5), 522–531.

By: N. Solban, I. Rizvi & T. Hasan

Contributors: N. Solban, I. Rizvi & T. Hasan

Source: ORCID
Added: July 15, 2024

2006 journal article

The Molecular Basis of Vitamin D Receptor and β-Catenin Crossregulation

Molecular Cell, 21(6), 799–809.

By: S. Shah, N. Islam, S. Dakshanamurthy, I. Rizvi, M. Rao, R. Herrell, G. Zinser, M. Valrance ...

Contributors: S. Shah, N. Islam, S. Dakshanamurthy, I. Rizvi, M. Rao, R. Herrell, G. Zinser, M. Valrance ...

Source: ORCID
Added: July 15, 2024

2006 journal article

Three-dimensional miniature endoscopy

Nature, 443, 765.

By: D. Yelin, I. Rizvi, W. White, J. Motz, T. Hasan, B. Bouma, G. Tearney

Contributors: D. Yelin, I. Rizvi, W. White, J. Motz, T. Hasan, B. Bouma, G. Tearney

Source: ORCID
Added: July 15, 2024

2005 journal article

Synergism of epidermal growth factor receptor-targeted immunotherapy with photodynamic treatment of ovarian cancer in vivo

Journal of the National Cancer Institute, 97(20), 1516–1524.

By: M. Carmen, I. Rizvi, Y. Chang, A. Moor, E. Oliva, M. Sherwood, B. Pogue, T. Hasan

Contributors: M. Carmen, I. Rizvi, Y. Chang, A. Moor, E. Oliva, M. Sherwood, B. Pogue, T. Hasan

Source: ORCID
Added: July 15, 2024

2003 journal article

Pegylation of charged polymer-photosensitiser conjugates: effects on photodynamic efficacy

British Journal of Cancer, 89, 937–943.

By: M. Hamblin, J. Miller, I. Rizvi, H. Loew & T. Hasan

Contributors: M. Hamblin, J. Miller, I. Rizvi, H. Loew & T. Hasan

Source: ORCID
Added: July 15, 2024

2002 journal article

Degree of substitution of chlorin e(6) on charged poly- L-lysine chains affects their cellular uptake, localization and phototoxicity towards macrophages and cancer cells

Journal of X-Ray Science and Technology, 10(3-4), 139–152.

By: M. Hamblin, J. Miller, I. Rizvi & B. Ortel

Contributors: M. Hamblin, J. Miller, I. Rizvi & B. Ortel

Source: ORCID
Added: July 15, 2024

2001 journal article

Pegylation of a chlorin(e6) polymer conjugate increases tumor targeting of photosensitizer

Cancer Research, 61, 7155–7162.

By: M. Hamblin, J. Miller, I. Rizvi, B. Ortel, E. Maytin & T. Hasan

Contributors: M. Hamblin, J. Miller, I. Rizvi, B. Ortel, E. Maytin & T. Hasan

Source: ORCID
Added: July 15, 2024

2000 journal article

Biodistribution of charged 17.1A photoimmunoconjugates in a murine model of hepatic metastasis of colorectal cancer

British Journal of Cancer, 83, 1544–1551.

By: M. Hamblin, M. Del Governatore, I. Rizvi & T. Hasan

Contributors: M. Hamblin, M. Del Governatore, I. Rizvi & T. Hasan

Source: ORCID
Added: July 15, 2024

2000 journal article

Experimental photoimmunotherapy of hepatic metastases of colorectal cancer with a 17.1A chlorin(e6) immunoconjugate

Cancer Research, 60, 4200–4205.

By: M. Del Governatore, M. Hamblin, C. Shea, I. Rizvi, K. Molpus, K. Tanabe, T. Hasan

Contributors: M. Del Governatore, M. Hamblin, C. Shea, I. Rizvi, K. Molpus, K. Tanabe, T. Hasan

Source: ORCID
Added: July 15, 2024

2000 journal article

Intraperitoneal photoimmunotherapy of ovarian carcinoma xenografts in nude mice using charged photoimmunoconjugates

Gynecologic Oncology, 76, 397–404.

By: K. Molpus, M. Hamblin, I. Rizvi & T. Hasan

Contributors: K. Molpus, M. Hamblin, I. Rizvi & T. Hasan

Source: ORCID
Added: July 15, 2024

1997 journal article

Pegylated poly-L-lysine chlorin-e6 conjugates as photosensitizers

Photochemistry and Photobiology, 65(SPEC. ISSUE), 8S.

By: M. Hamblin, J. Miller, I. Rizvi & T. Hasan

Contributors: M. Hamblin, J. Miller, I. Rizvi & T. Hasan

Source: ORCID
Added: July 15, 2024

Education

Updated: July 20th, 2014 15:24

2006 - 2010

Dartmouth College Hanover, NH, US
Ph.D. Thayer School of Engineering

2002 - 2003

Georgetown University Washington, DC, US
M.S. Lombardi Comprehensive Cancer Center

1997 - 2002

Johns Hopkins University Baltimore, MD, US
B.A.

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.