Imran Rizvi

Chronic PFAS exposure induces chemotherapy resistance by promoting mitochondria-related alterations in ovarian cancer cells

Rickard, B. P., Sapienza-Lundie, L. A., Overchuk, M., Tulino, J., Mori, M. P., McCord, J. P., … Rizvi, I. (2025, June 21). Environmental Research, Vol. 284.

Mitochondrial membrane hyperpolarization modulates nuclear DNA methylation and gene expression through phospholipid remodeling

Mori, M. P., Lozoya, O. A., Brooks, A. M., Bortner, C. D., Nadalutti, C. A., Ryback, B., … Santos, J. H. (2025, April 29). Nature Communications, Vol. 16.

Photodynamic priming ( PDP ) targets platinum resistance from chronic perfluoroalkyl substances ( PFAS ) exposure in ovarian cancer cells

Rickard, B. P., Dillon, M. M., Sapienza‐Lundie, L. A., Fenton, S. E., & Rizvi, I. (2025, November 6). Photochemistry and Photobiology.

Photodynamic priming overcomes platinum resistance from short‐term exposure to select perfluoroalkyl substances in endometrial cancer cell lines

Rickard, B. P., Sapienza‐Lundie, L. A., Overchuk, M., Tan, X., Bae‐Jump, V. L., Yates, M. S., … Rizvi, I. (2025, March 10). Photochemistry and Photobiology, Vol. 101, pp. 1177–1198.

PpIX‐enabled fluorescence‐based detection and photodynamic priming of platinum‐resistant ovarian cancer cells under fluid shear stress

Ruhi, M. K., Rickard, B. P., Overchuk, M., Sinawang, P. D., Stanley, E., Mansi, M., … Rizvi, I. (2024, August 27). Photochemistry and Photobiology, Vol. 8.

Fractionated photoimmunotherapy stimulates an anti-tumour immune response: an integrated mathematical and in vitro study

Zahid, M. U., Waguespack, M., Harman, R. C., Kercher, E. M., Nath, S., Hasan, T., … Enderling, H. (2024, September 11). British Journal of Cancer, Vol. 9.

Overcoming the effects of fluid shear stress in ovarian cancer cell lines: Doxorubicin alone or photodynamic priming to target platinum resistance

Overchuk, M., Rickard, B. P., Tulino, J., Tan, X., Ligler, F. S., Huang, H. C., & Rizvi, I. (2024, June 7). Photochemistry and Photobiology, Vol. 6.

Development of a light emitting device for the treatment of peritoneal carcinomatosis of ovarian origin by intracavitary photodynamic therapy

ZIANE, L., BAERT, G., MORALES, O., VIGNION-DEWALLE, A.-S., & DELHEM, N. (2023, March 1). Photodiagnosis and Photodynamic Therapy, Vol. 41.

Exposure to select PFAS and PFAS mixtures alters response to platinum-based chemotherapy in endometrial cancer cell lines

Environmental Health, 22(1).

Methods to Evaluate Changes in Mitochondrial Structure and Function in Cancer

Cancers, 15(9), 2564.

Targeted PDT Combinations to Overcome Fluid Shear Stress-induced Platinum Resistance in Ovarian Cancer

OVERCHUK, M., RUHI, M. K., RICKARD, B., LIGLER, F., & RIZVI, I. (2023, March 1). Photodiagnosis and Photodynamic Therapy, Vol. 41.

Transient fluid flow improves photoimmunoconjugate delivery and photoimmunotherapy efficacy

Sorrin, A. J., Zhou, K., May, K., Liu, C., McNaughton, K., Rahman, I., … Huang, H.-C. (2023, June 26). IScience, Vol. 26.

Critical PDT theory II: Current concepts and indications

Kessel, D., Obaid, G., & Rizvi, I. (2022, May 21). Photodiagnosis and Photodynamic Therapy, Vol. 39.

Photochemical Targeting of Mitochondria to Overcome Chemoresistance in Ovarian Cancer^†

Photochemistry and Photobiology, 99(2), 448–468.

Photodynamic Priming Overcomes Per‐ and Polyfluoroalkyl Substance (PFAS

Photochemistry and Photobiology, 99(2), 793–813.

Photodynamic Stromal Depletion Enhances Therapeutic Nanoparticle Delivery in 3D Pancreatic Ductal Adenocarcinoma Tumor Models

Karimnia, V., Stanley, M. E., Fitzgerald, C. T., Rizvi, I., Slack, F. J., & Celli, J. P. (2022, June 14). Photochemistry and Photobiology, Vol. 8.

Select Per- and Polyfluoroalkyl Substances (PFAS) Induce Resistance to Carboplatin in Ovarian Cancer Cell Lines

International Journal of Molecular Sciences, 23(9), 5176.

Water transport regulates nucleus volume, cell density, Young’s modulus, and E-cadherin expression in tumor spheroids

Conrad, C., Conway, J., Polacheck, W. J., Rizvi, I., & Scarcelli, G. (2022, September 1). European Journal of Cell Biology.

Emerging biofabrication approaches for gastrointestinal organoids towards patient specific cancer models

Soto, F., Guimarães, C. F., Reis, R. L., Franco, W., Rizvi, I., & Demirci, U. (2021, February 9). Cancer Letters, Vol. 504, pp. 116–124.

Malignant Ascites in Ovarian Cancer: Cellular, Acellular, and Biophysical Determinants of Molecular Characteristics and Therapy Response

Rickard, B. P., Conrad, C., Sorrin, A. J., Ruhi, M. K., Reader, J. C., Huang, S. A., … Rizvi, I. (2021, August 26). Cancers, Vol. 13, p. 4318.

Mechanical Modulation of Ovarian Cancer Tumor Nodules Under Flow

Conrad, C., Moore, K., Polacheck, W., Rizvi, I., & Scarcelli, G. (2021, June 28). IEEE Transactions on Biomedical Engineering, Vol. 69, pp. 294–301.

Per- and poly-fluoroalkyl substances (PFAS) and female reproductive outcomes: PFAS elimination, endocrine-mediated effects, and disease

Toxicology, 465, 153031.

Cabozantinib Inhibits Photodynamic Therapy-Induced Auto- and Paracrine MET Signaling in Heterotypic Pancreatic Microtumors

Broekgaarden, M., Alkhateeb, A., Bano, S., Bulin, A.-L., Obaid, G., Rizvi, I., & Hasan, T. (2020, May 29). Cancers.

Flow-induced Shear Stress Confers Resistance to Carboplatin in an Adherent Three-Dimensional Model for Ovarian Cancer: A Role for EGFR-Targeted Photoimmunotherapy Informed by Physical Stress

Nath, S., Pigula, M., Khan, A. P., Hanna, W., Ruhi, M. K., Dehkordy, F. M., … Rizvi, I. (2020, March 28). Journal of Clinical Medicine.

Photodestruction of Stromal Fibroblasts Enhances Tumor Response to PDT in 3D Pancreatic Cancer Coculture Models

Karimnia, V., Rizvi, I., Slack, F. J., & Celli, J. P. (2020, October 4). Photochemistry and Photobiology, Vol. 97, pp. 416–426.

Photodynamic Therapy and the Biophysics of the Tumor Microenvironment

Sorrin, A. J., Ruhi, M. K., Ferlic, N. A., Karimnia, V., Polacheck, W. J., Celli, J. P., … Rizvi, I. (2020, January 2). Photochemistry and Photobiology.

Vitamin D Receptor Activation and Photodynamic Priming Enables Durable Low-dose Chemotherapy

Anbil, S., Pigula, M., Huang, H.-C., Mallidi, S., Broekgaarden, M., Baglo, Y., … Hasan, T. (2020, March 27). Molecular Cancer Therapeutics, Vol. 19, pp. 1308–1319.

Cancer Cell‐targeted and Activatable Photoimmunotherapy Spares T Cells in a 3D Coculture Model

Kercher, E. M., Nath, S., Rizvi, I., & Spring, B. Q. (2019, August 19). Photochemistry and Photobiology.

Illuminating the Numbers: Integrating Mathematical Models to Optimize Photomedicine Dosimetry and Combination Therapies

Spring, B. Q., Lang, R. T., Kercher, E. M., Rizvi, I., Wenham, R. M., Conejo-Garcia, J. R., … Enderling, H. (2019, April 2). Frontiers in Physics, Vol. 7.

Mechanical Characterization of 3D Ovarian Cancer Nodules Using Brillouin Confocal Microscopy

Conrad, C., Gray, K. M., Stroka, K. M., Rizvi, I., & Scarcelli, G. (2019, May 7). Cellular and Molecular Bioengineering, Vol. 12, pp. 215–226.

A Combination of Visudyne and a Lipid‐anchored Liposomal Formulation of Benzoporphyrin Derivative Enhances Photodynamic Therapy Efficacy in a 3D Model for Ovarian Cancer

Rizvi, I., Nath, S., Obaid, G., Ruhi, M. K., Moore, K., Bano, S., … Hasan, T. (2018, November 30). Photochemistry and Photobiology.

Neoadjuvant photodynamic therapy augments immediate and prolonged oxaliplatin efficacy in metastatic pancreatic cancer organoids

Broekgaarden, M., Rizvi, I., Bulin, A.-L., Petrovic, L., Goldschmidt, R., Massodi, I., … Hasan, T. (2018, February 6). Oncotarget.

Photodynamic therapy: Promoting in vitro efficacy of photodynamic therapy by liposomal formulations of a photosensitizing agent

Rizvi, I., Obaid, G., Bano, S., Hasan, T., & Kessel, D. (2018, March 11). Lasers in Surgery and Medicine.

Mechanism-informed Repurposing of Minocycline Overcomes Resistance to Topoisomerase Inhibition for Peritoneal Carcinomatosis

Huang, H.-C., Liu, J., Baglo, Y., Rizvi, I., Anbil, S., Pigula, M., & Hasan, T. (2017, November 23). Molecular Cancer Therapeutics.

Photodynamic Priming Mitigates Chemotherapeutic Selection Pressures and Improves Drug Delivery

Huang, H.-C., Rizvi, I., Liu, J., Anbil, S., Kalra, A., Lee, H., … Hasan, T. (2017, November 29). Cancer Research.

Photodynamic Therapy Synergizes with Irinotecan to Overcome Compensatory Mechanisms and Improve Treatment Outcomes in Pancreatic Cancer

Huang, H.-C., Mallidi, S., Liu, J., Chiang, C.-T., Mai, Z., Goldschmidt, R., … Hasan, T. (2016, January 12). Cancer Research.

In vivoevaluation of battery-operated light-emitting diode-based photodynamic therapy efficacy using tumor volume and biomarker expression as endpoints

Mallidi, S., Mai, Z., Rizvi, I., Hempstead, J., Arnason, S., Celli, J., & Hasan, T. (2015, April 24). Journal of Biomedical Optics.

Low-cost photodynamic therapy devices for global health settings: Characterization of battery-powered LED performance and smartphone imaging in 3D tumor models

Hempstead, J., Jones, D. P., Ziouche, A., Cramer, G. M., Rizvi, I., Arnason, S., … Celli, J. P. (2015, May 12). Scientific Reports.

The role of photodynamic therapy in overcoming cancer drug resistance

Spring, B. Q., Rizvi, I., Xu, N., & Hasan, T. (2015, March 10). Photochemical & Photobiological Sciences.

An imaging-based platform for high-content, quantitative evaluation of therapeutic response in 3D tumour models

Celli, J. P., Rizvi, I., Blanden, A. R., Massodi, I., Glidden, M. D., Pogue, B. W., & Hasan, T. (2014, January 17). Scientific Reports.

Selective treatment and monitoring of disseminated cancer micrometastases in vivo using dual-function, activatable immunoconjugates

Spring, B. Q., Abu-Yousif, A. O., Palanisami, A., Rizvi, I., Zheng, X., Mai, Z., … Hasan, T. (2014, February 26). Proceedings of the National Academy of Sciences.

“Pointsource” Delivery of a Photosensitizer Drug and Singlet Oxygen: Eradication of Glioma Cells In Vitro

Ghogare, A. A., Rizvi, I., Hasan, T., & Greer, A. (2014, March 27). Photochemistry and Photobiology.

PDT Dose Parameters Impact Tumoricidal Durability and Cell Death Pathways in a 3D Ovarian Cancer Model

Rizvi, I., Anbil, S., Alagic, N., Celli, J. P., Zheng, L. Z., Palanisami, A., … Hasan, T. (2013, February 27). Photochemistry and Photobiology, Vol. 89, pp. 942–952.

Flow induces epithelial-mesenchymal transition, cellular heterogeneity and biomarker modulation in 3D ovarian cancer nodules

Rizvi, I., Gurkan, U. A., Tasoglu, S., Alagic, N., Celli, J. P., Mensah, L. B., … Hasan, T. (2013, May 3). Proceedings of the National Academy of Sciences, Vol. 110, pp. E1974–E1983.

Impact of treatment response metrics on photodynamic therapy planning and outcomes in a three-dimensional model of ovarian cancer

Anbil, S., Rizvi, I., Celli, J. P., Alagic, N., Pogue, B. W., & Hasan, T. (2013, September 25). Journal of Biomedical Optics, Vol. 18, p. 098004.

Image-Based Quantification of Benzoporphyrin Derivative Uptake, Localization, and Photobleaching in 3D Tumor Models, for Optimization of PDT Parameters

Glidden, M. D., Celli, J. P., Massodi, I., Rizvi, I., Pogue, B. W., & Hasan, T. (2012, January 1). Theranostics, Vol. 2, pp. 827–839.

Photoimmunotherapy and Irradiance Modulation Reduce Chemotherapy Cycles and Toxicity in a Murine Model for Ovarian Carcinomatosis: Perspective and Results

Rizvi, I., Dinh, T. A., Yu, W., Chang, Y., Sherwood, M. E., & Hasan, T. (2012, September 1). Israel Journal of Chemistry, Vol. 52, pp. 776–787.

A three‐dimensional in vitro ovarian cancer coculture model using a high‐throughput cell patterning platform

Xu, F., Celli, J., Rizvi, I., Moon, S., Hasan, T., & Demirci, U. (2011, February 1). Biotechnology Journal, Vol. 6, pp. 204–212.

Killing Hypoxic Cell Populations in a 3D Tumor Model with EtNBS-PDT

Evans, C. L., Abu-Yousif, A. O., Park, Y. J., Klein, O. J., Celli, J. P., Rizvi, I., … Hasan, T. (2011, August 18). PLoS ONE, Vol. 6.

Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization

Celli, J. P., Spring, B. Q., Rizvi, I., Evans, C. L., Samkoe, K. S., Verma, S., … Hasan, T. (2010, March 30). Chemical Reviews, Vol. 110, pp. 2795–2838.

Ki-67 as a Molecular Target for Therapy in anIn vitroThree-Dimensional Model for Ovarian Cancer

Rahmanzadeh, R., Rai, P., Celli, J. P., Rizvi, I., Baron-Lühr, B., Gerdes, J., & Hasan, T. (2010, November 7). Cancer Research, Vol. 70, pp. 9234–9242.

Quantitative imaging reveals heterogeneous growth dynamics and treatment-dependent residual tumor distributions in a three-dimensional ovarian cancer model

Celli, J. P., Rizvi, I., Evans, C. L., Abu-Yousif, A. O., & Hasan, T. (2010, September 1). Journal of Biomedical Optics, Vol. 15.

Synergistic Enhancement of Carboplatin Efficacy with Photodynamic Therapy in a Three-Dimensional Model for Micrometastatic Ovarian Cancer

Rizvi, I., Celli, J. P., Evans, C. L., Abu-Yousif, A. O., Muzikansky, A., Pogue, B. W., … Hasan, T. (2010, November 10). Cancer Research, Vol. 70, pp. 9319–9328.

Imaging Tumor Variation in Response to Photodynamic Therapy in Pancreatic Cancer Xenograft Models

Samkoe, K. S., Chen, A., Rizvi, I., O'Hara, J. A., Hoopes, P. J., Pereira, S. P., … Pogue, B. W. (2009, December 11). International Journal of Radiation Oncology*Biology*Physics, Vol. 76, pp. 251–259.

In vitro ovarian tumor growth and treatment response dynamics visualized with time-lapse OCT imaging

Optics Express, 17(11), 8892–8906.

In vivo high-resolution fluorescence microendoscopy for ovarian cancer detection and treatment monitoring

Zhong, W., Celli, J. P., Rizvi, I., Mai, Z., Spring, B. Q., Yun, S. H., & Hasan, T. (2009, November 17). British Journal of Cancer, Vol. 101, pp. 2015–2022.

PuraMatrix Encapsulation of Cancer Cells

Abu-Yousif, A. O., Rizvi, I., Evans, C. L., Celli, J. P., & Hasan, T. (2009, December 17). Journal of Visualized Experiments.

In vivoOptical Molecular Imaging of Vascular Endothelial Growth Factor for Monitoring Cancer Treatment

Chang, S. K., Rizvi, I., Solban, N., & Hasan, T. (2008, July 1). Clinical Cancer Research, Vol. 14, pp. 4146–4153.

In-vivo singlet oxygen dosimetry of clinical 5-aminolevulinic acid photodynamic therapy

Laubach, H.-J., Chang, S. K., Lee, S., Rizvi, I., Zurakowski, D., Davis, S. J., … Hasan, T. (2008, January 1). Journal of Biomedical Optics, Vol. 13.

A Mechanism-Based Combination Therapy Reduces Local Tumor Growth and Metastasis in an Orthotopic Model of Prostate Cancer

Kosharskyy, B., Solban, N., Chang, S. K., Rizvi, I., Chang, Y., & Hasan, T. (2006, November 15). Cancer Research, Vol. 66, pp. 10953–10958.

In Vivo Imaging of VEGF Expression for Monitoring Molecular Response to Cancer Therapy

Chang, S. K., Rizvi, I., Solban, N., & Hasan, T. (2006, January 1). Biomedical Optics, p. TuC4.

Targeted photodynamic therapy

Solban, N., Rizvi, I., & Hasan, T. (2006, May 2). Lasers in Surgery and Medicine, Vol. 38, pp. 522–531.

The Molecular Basis of Vitamin D Receptor and β-Catenin Crossregulation

Shah, S., Islam, M. N., Dakshanamurthy, S., Rizvi, I., Rao, M., Herrell, R., … Byers, S. W. (2006, March 1). Molecular Cell, Vol. 21, pp. 799–809.

Three-dimensional miniature endoscopy

Yelin, D., Rizvi, I., White, W. M., Motz, J. T., Hasan, T., Bouma, B. E., & Tearney, G. J. (2006, October 18). Nature, Vol. 443, p. 765.

Synergism of Epidermal Growth Factor Receptor–Targeted Immunotherapy With Photodynamic Treatment of Ovarian Cancer In Vivo

Carmen, M. G., Rizvi, I., Chang, Y., Moor, A. C. E., Oliva, E., Sherwood, M., … Hasan, T. (2005, October 18). JNCI Journal of the National Cancer Institute, Vol. 97, pp. 1516–1524.

Pegylation of charged polymer-photosensitiser conjugates: effects on photodynamic efficacy

Hamblin, M. R., Miller, J. L., Rizvi, I., Loew, H. G., & Hasan, T. (2003, August 26). British Journal of Cancer, Vol. 89, pp. 937–943.

Degree of substitution of chlorin e(6) on charged poly- L-lysine chains affects their cellular uptake, localization and phototoxicity towards macrophages and cancer cells

Journal of X-Ray Science and Technology, 10(3-4), 139–152.

Pegylation of a chlorin(e6) polymer conjugate increases tumor targeting of photosensitizer

Cancer Research, 61, 7155–7162.

Biodistribution of charged 17.1A photoimmunoconjugates in a murine model of hepatic metastasis of colorectal cancer

Hamblin, M. R., Governatore, M. D., Rizvi, I., & Hasan, T. (2000, December 1). British Journal of Cancer, Vol. 83, pp. 1544–1551.

Experimental photoimmunotherapy of hepatic metastases of colorectal cancer with a 17.1A chlorin(e6) immunoconjugate

Cancer Research, 60, 4200–4205.

Intraperitoneal Photoimmunotherapy of Ovarian Carcinoma Xenografts in Nude Mice Using Charged Photoimmunoconjugates

Molpus, K. L., Hamblin, M. R., Rizvi, I., & Hasan, T. (2000, March 1). Gynecologic Oncology, Vol. 76, pp. 397–404.

Pegylated poly-L-lysine chlorin-e6 conjugates as photosensitizers

Photochemistry and Photobiology, 65(SPEC. ISSUE), 8S.