2014 journal article

In vitro dermal and epidermal cellular response to titanium alloy implants fabricated with electron beam melting

MEDICAL ENGINEERING & PHYSICS, 36(10), 1367–1372.

By: J. Springer n, O. Harrysson n, D. Marcellin-Little n & S. Bernacki n

author keywords: Keratinocyte; Fibroblast; Additive manufacturing; Electron beam melting; Titanium alloy; Biocompatibility
MeSH headings : Alloys; Cell Proliferation / drug effects; Cell Survival / drug effects; Dermis / cytology; Electrons; Epidermal Cells; Fibroblasts / cytology; Fibroblasts / drug effects; Humans; Keratinocytes / cytology; Keratinocytes / drug effects; Materials Testing; Osseointegration / drug effects; Phase Transition; Prostheses and Implants; Surface Properties; Titanium / chemistry; Titanium / pharmacology
TL;DR: Electron beam melting EBM Ti6Al4V discs exhibited an acceptable biocompatibility profile compared to solid titanium alloy discs from a commercial source for dermal and epidermal cells, and may be considered as an option for fabrication of custom transdermal implants. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

In vitro biocompatibility of titanium alloy discs made using direct metal fabrication

MEDICAL ENGINEERING & PHYSICS, 32(6), 645–652.

By: C. Haslauer n, J. Springer n, O. Harrysson n, E. Loboa n, N. Monteiro-Riviere n & D. Marcellin-Little n

Contributors: C. Haslauer n, J. Springer n, O. Harrysson n, E. Loboa n, N. Monteiro-Riviere n & D. Marcellin-Little n

author keywords: Biocompatibility; Orthopedic implant; Free-form fabrication; Direct metal fabrication; Electron beam melting; Stem cell; Human stem cell
MeSH headings : Adipose Tissue / cytology; Alloys / chemical synthesis; Alloys / chemistry; Alloys / pharmacology; Aluminum / chemistry; Cell Proliferation / drug effects; Cell Survival / drug effects; Female; Humans; Interleukin-6 / metabolism; Interleukin-8 / metabolism; Materials Testing / methods; Middle Aged; Stem Cells / cytology; Stem Cells / drug effects; Stem Cells / metabolism; Surface Properties; Titanium / chemistry; Titanium / pharmacology; Vanadium / chemistry
TL;DR: In vitro biocompatibility of EBM titanium-6 aluminum-4 vanadium (Ti6Al4V) structures is assessed by comparing the cellular response to solid polished, solid unpolished, and porous EBM discs to the Cellular response to discs made of commercially produced Ti6Al 4V. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

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