Works (277)

Updated: July 19th, 2024 05:02

2024 personal communication

A call from 40 public health scientists for an end to the continuing humanitarian and environmental catastrophe in Gaza

London, L., Watterson, A., Mergler, D., Albin, M., Andrade-Rivas, F., Di Ciaula, A., … White, R. (2024, June 28).

By: L. London, A. Watterson, D. Mergler, M. Albin, F. Andrade-Rivas, A. Di Ciaula, P. Comba, F. Giannasi ...

author keywords: War; Gaza; Environmental impacts; Remediation
Sources: Web Of Science, NC State University Libraries
Added: July 17, 2024

2024 article

Measurement of Hydro-EVE and 6:2 FTS in Blood from Wilmington, North Carolina, Residents, 2017-2018

Kotlarz, N., McCord, J., Wiecha, N., Weed, R. A., Cuffney, M., Enders, J. R., … Hoppin, J. A. (2024, February). ENVIRONMENTAL HEALTH PERSPECTIVES, Vol. 132.

By: N. Kotlarz n, J. McCord*, N. Wiecha n, R. Weed*, M. Cuffney n, J. Enders n, M. Strynar*, D. Knappe n, B. Reich n, J. Hoppin n

Sources: Web Of Science, NC State University Libraries, ORCID
Added: March 21, 2024

2024 journal article

Pesticide exposure, birth size, and gestational age in the ISA birth cohort, Costa Rica

ENVIRONMENTAL EPIDEMIOLOGY, 8(2).

TL;DR: Prenatal exposure to chlorpyrifos and 2,4-D, and, possibly, mancozeb/ETU, and, possibly, mancozeb/ETU, may impair fetal growth. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 14, 2024

2024 article

Reanalysis of PFO5DoA Levels in Blood from Wilmington, North Carolina, Residents, 2017-2018

Kotlarz, N., McCord, J., Wiecha, N., Weed, R. A., Cuffney, M., Enders, J. R., … Hoppin, J. A. (2024, February). ENVIRONMENTAL HEALTH PERSPECTIVES, Vol. 132.

By: N. Kotlarz n, J. McCord*, N. Wiecha n, R. Weed*, M. Cuffney n, J. Enders n, M. Strynar*, D. Knappe n, B. Reich n, J. Hoppin n

Sources: Web Of Science, NC State University Libraries, ORCID
Added: March 21, 2024

2023 journal article

A cross-sectional analysis of medical conditions and environmental factors associated with fractional exhaled nitric oxide (FeNO) in women and children from the ISA birth cohort, Costa Rica

ENVIRONMENTAL RESEARCH, 233.

By: D. Werthmann n, B. Joode*, M. Cuffney n, B. Reich n, M. Soto-Martinez*, A. Corrales-Vargas*, L. Palomo-Cordero*, J. Penaloza-Castanedac, J. Hoppin n

author keywords: Asthma FeNO pesticides environment rhinitis; wheeze
TL;DR: Rinitis and wheeze were associated with elevated FeNO in this rural, agricultural population of women and children, and smoke from waste burning as well as para-occupational pesticide exposure may contribute to elevatedFeNO in rural communities. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 25, 2023

2023 article

Detection of the fungicide transformation product 4-hydroxychlorothalonil in serum of pregnant women from Sweden and Costa Rica

Krais, A. M. M., Joode, B. van W., Liljedahl, E. R., Blomberg, A. J., Ronnholm, A., Bengtsson, M., … Lindh, C. H. H. (2023, July 20). JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY, Vol. 7.

By: A. Krais*, B. Joode*, E. Liljedahl*, A. Blomberg*, A. Ronnholm*, M. Bengtsson*, J. Cano*, J. Hoppin n ...

author keywords: Chlorothalonil; Fungicide; Exposure biomarker; Human biomonitoring; Aerial spraying; Pesticides
TL;DR: For the first time, this study quantifies human exposure to the fungicide chlorothalonil and/or its transformation product 4-hydroxychlorothalonin and finds higher serum concentrations in women from a tropical agricultural setting as compared with women from the general population in Sweden. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 14, 2023

2023 journal article

Estimation of the Half-Lives of Recently Detected Per- and Polyfluorinated Alkyl Ethers in an Exposed Community

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 57(41), 15348–15355.

author keywords: exposure; PFAS; water; humans; environment; toxicokinetic modeling
TL;DR: These fluoroethers had biological half-Lives longer than published half-lives for PFHxA and PFHpA but shorter than those for PFOA andPFOS (800-1200 days). (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: October 7, 2023

2023 journal article

Factors associated with per- and polyfluoroalkyl substances (PFAS) serum concentrations in residents of New Hanover County, North Carolina: The GenX exposure study

ENVIRONMENTAL RESEARCH, 237.

By: M. Cuffney n, A. Wilkie n, N. Kotlarz n, D. Knappe n, C. Lea n, D. Collier n, J. Dewitt n, J. Hoppin n

author keywords: Per-and polyfluoroalkyl substances (PFAS); Fluoroethers; Contaminated drinking water; Environmental exposure predictors
TL;DR: It is shown that drinking water is a primary source for serum PFAS concentrations among New Hanover County residents and years of residence in the lower Cape Fear Region as a surrogate for water consumption were important for both the association and predictive investigations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: September 4, 2023

2023 journal article

PFAS levels in paired drinking water and serum samples collected from an exposed community in Central North Carolina

SCIENCE OF THE TOTAL ENVIRONMENT, 895.

By: S. Hall*, S. Zhang*, G. Tait*, K. Hoffman*, D. Collier n, J. Hoppin n, H. Stapleton*

author keywords: Per-andpolyfluoroalkyl substances; PFAS; Drinking water; Serum; Human health outcomes
TL;DR: Extensive exposure to PFAS in Pittsboro is revealed and associations with clinical blood markers are revealed, suggesting potential health impacts in community residents. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: September 11, 2023

2023 journal article

Source apportionment of serum PFASs in two highly exposed communities

SCIENCE OF THE TOTAL ENVIRONMENT, 855.

By: D. Wallis n, K. Barton*, D. Knappe n, N. Kotlarz n, C. McDonough*, C. Higgins*, J. Hoppin n, J. Adgate*

author keywords: Source apportionment; Receptor models; PFAS; Per fluoroalkyl substances
MeSH headings : Humans; Fluorocarbons / analysis; Nutrition Surveys; Drinking Water / analysis; Multivariate Analysis; Principal Component Analysis; Alkanesulfonic Acids / analysis; Water Pollutants, Chemical / analysis
TL;DR: Effectiveness of three source apportionment methods for identifying contributors to human serum PFAS concentrations in two highly exposed populations in Colorado and North Carolina where drinking water was contaminated via upstream sources is assessed. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: October 11, 2022

2023 journal article

Timing and Trends for Municipal Wastewater, Lab-Confirmed Case , and Syndromic Case Surveillance of COVID-19 in Raleigh, North Carolina

AMERICAN JOURNAL OF PUBLIC HEALTH, 113(1), 79–88.

By: N. Kotlarz n, D. Holcomb n, T. Pasha n, S. Reckling n, J. Kays n, Y. Lai n, S. Daly n, S. Palani n ...

Contributors: N. Kotlarz n, D. Holcomb n, T. Pasha n, S. Reckling n, J. Kays n, Y. Lai n, S. Daly n, S. Palani n ...

MeSH headings : Humans; COVID-19 / epidemiology; SARS-CoV-2; Wastewater; North Carolina / epidemiology; Sentinel Surveillance; RNA, Viral
TL;DR: The results provide evidence for investment in SARS-CoV-2 wastewater and CLI surveillance to complement information provided through lab-confirmed cases, and in a major metropolitan area in 2020, the timing of and trends in municipal wastewater, lab- confirmed case, and syndromic case surveillance of COVID-19 were in general agreement. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: January 30, 2023

2022 article

Allergic and non-allergic wheeze among farm women in the Agricultural Health Study (2005-2010)

Islam, J. Y., Mohamed, A., Umbach, D. M., London, S. J., Henneberger, P. K., Freeman, L. E. B., … Hoppin, J. A. (2022, August 8). OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, Vol. 8.

By: J. Islam n, A. Mohamed n, D. Umbach*, S. London, P. Henneberger*, L. Freeman*, D. Sandler, J. Hoppin n

author keywords: Allergy; Pesticides; Respiratory System
TL;DR: Use of specific pesticides and certain farm activities may contribute to wheeze among farm women, as evaluated in the Agricultural Health Study. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: August 9, 2022

2022 journal article

Drinking Water-Associated PFAS and Fluoroethers and Lipid Outcomes in the GenX Exposure Study

ENVIRONMENTAL HEALTH PERSPECTIVES, 130(9).

By: E. Rosen*, N. Kotlarz n, D. Knappe n, C. Lea*, D. Collier*, D. Richardson*, J. Hoppin n

MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Alkanesulfonic Acids; Child; Cholesterol; Cross-Sectional Studies; Drinking Water; Environmental Pollutants; Fluorocarbons; Humans; Lipids; Middle Aged; Young Adult
TL;DR: PFNA and PFOS were associated with higher levels of total and non-HDL cholesterol, with associations larger in magnitude among older adults, and fluoroethers appeared to be associated with HDL but not non- HDL lipid measures. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: September 8, 2022

2022 journal article

Exposure to common-use pesticides, manganese, lead, and thyroid function among pregnant women from the Infants' Environmental Health (ISA) study, Costa Rica

SCIENCE OF THE TOTAL ENVIRONMENT, 810.

By: A. Vargas*, J. Castaneda*, E. Liljedahl*, A. Mora*, J. Menezes-Filho*, D. Smith*, D. Mergler*, B. Reich n ...

author keywords: Thyroid function; Endocrine disruptors; Pesticides; Metals; Latin America
MeSH headings : Bayes Theorem; Costa Rica; Environmental Exposure / adverse effects; Female; Humans; Infant; Lead / adverse effects; Manganese / adverse effects; Pesticides / adverse effects; Pregnancy; Pregnant Women; Thyroid Gland / physiopathology; Thyrotropin; Thyroxine; Triiodothyronine
TL;DR: Mancozeb (ETU) and pyrimethanil may inhibit FT4 secretion (hypothyroidism-like effect), while chlorpyrifos, pyrethroids, MnB, MnH, PbB and Mn showed hyperthyroidism -like effects. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: April 4, 2022

2022 journal article

Pyrimethanil and chlorpyrifos air concentrations and pregnant women's urinary metabolites in the Infants' Environmental Health Study (ISA) Costa Rica ,

ENVIRONMENT INTERNATIONAL, 166.

By: A. Giffin n, J. Hoppin n, L. Cordoba*, K. Solano-Diaz*, C. Ruepert*, J. Penaloza-Castaneda*, C. Lindh*, B. Reich n, B. Joode*

author keywords: Urinary pesticide metabolites; Airborne pesticide exposure; Spatiotemporal model; Environmental exposure; Pesticides; Insecticides; Fungicides
TL;DR: The results suggest inhalation of pyrimethanil and chlorpyrifos is a pathway of environmental exposure, and passive air samplers seems a useful technique to monitor environmental current-use pesticide exposures. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: July 11, 2022

2022 article

Respiratory and allergic outcomes among 5-year-old children exposed to pesticides

Islam, J. Y., Hoppin, J., Mora, A. M., Soto-Martinez, M. E., Cordoba Gamboa, L., Penaloza Castaneda, J. E., … Joode, B. (2022, February 24). THORAX, Vol. 2.

By: J. Islam n, J. Hoppin n, A. Mora*, M. Soto-Martinez*, L. Cordoba Gamboa*, J. Penaloza Castaneda*, B. Reich n, C. Lindh*, B. Joode*

author keywords: asthma epidemiology; paediatric asthma; respiratory infection
MeSH headings : Infant; Pregnancy; Female; Humans; Child, Preschool; Pesticides / toxicity; Cough; Asthma; Rhinitis, Allergic; Respiratory Tract Infections; Pyrethrins; Exanthema
TL;DR: Current pyrethroid exposure may affect children’s respiratory and allergic health at 5 years of age as pyrethroids are broadly used in home environments and agriculture and mancozeb in agriculture. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: March 28, 2022

2021 article

Environmental exposures contribute to respiratory and allergic symptoms among women living in the banana growing regions of Costa Rica

Alhanti, B., Joode, B. van W., Martinez, M. S., Mora, A. M., Gamboa, L. C., Reich, B., … Hoppin, J. A. (2021, December 30). OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, Vol. 12.

By: B. Alhanti n, B. Joode*, M. Martinez*, A. Mora*, L. Gamboa*, B. Reich n, C. Lindh*, M. Lepiz*, J. Hoppin n

author keywords: asthma; respiratory disease; allergy; pesticide; agriculture
MeSH headings : Asthma / epidemiology; Cohort Studies; Costa Rica / epidemiology; Eczema / epidemiology; Environmental Exposure / adverse effects; Exanthema / epidemiology; Female; Humans; Hypersensitivity / epidemiology; Musa; Pesticides / adverse effects; Respiratory Tract Diseases / epidemiology; Rhinitis / epidemiology; Smoke / adverse effects
TL;DR: Findings suggest that environmental exposure to both pesticides and smoke may impact respiratory and skin-related allergic outcomes in women. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: December 31, 2021

2021 journal article

Gender differences in respiratory health outcomes among farming cohorts around the globe: findings from the AGRICOH consortium

JOURNAL OF AGROMEDICINE, 26(2), 97–108.

By: J. Fix, I. Annesi-Maesano*, I. Baldi*, M. Boulanger*, S. Cheng*, S. Cortes*, J. Dalphin*, M. Dalvie* ...

author keywords: Farmers; Respiratory Health; Gender; Farmworkers; Occupational Exposure
MeSH headings : Adult; Agricultural Workers' Diseases / epidemiology; Agriculture; Female; Humans; Male; Occupational Exposure; Outcome Assessment, Health Care; Prevalence; Prospective Studies; Risk Factors; Sex Factors
TL;DR: Assessment of respiratory disease prevalence among adults in 18 cohorts representing over 200,000 farmers, farm workers, and their spouses from six continents indicates that respiratory outcomes are common among farmers around the world despite differences in agricultural production. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 6, 2020

2021 journal article

Gestational Phthalate Exposure and Preschool Attention Deficit Hyperactivity Disorder in Norway

ENVIRONMENTAL EPIDEMIOLOGY, 5(4).

By: E. Kamai*, G. Villanger*, R. Nethery*, C. Thomsen*, A. Sakhi*, S. Drover*, J. Hoppin n, G. Knudsen* ...

author keywords: phthalates; ADHD; Attention Deficit Hyperactivity Disorder; biomarkers; prenatal; gestational; MoBa; The Norwegian Mother; Father and Child Cohort Study
TL;DR: Results suggest gestational phthalate exposure may impact the behavior of children as young as 3 years, and boys, but not girls, mono-n-butyl phthalates exposure was associated with increased odds of ADHD. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: May 16, 2022

2020 journal article

Associations between urine phthalate metabolites and thyroid function in pregnant women and the influence of iodine status

ENVIRONMENT INTERNATIONAL, 137.

By: G. Villanger*, S. Drover*, R. Nethery*, C. Thomsen*, A. Sakhi*, K. Overgaard*, P. Zeiner*, J. Hoppin n ...

author keywords: Phthalates; Thyroid hormones; Pregnancy; Iodine; The Norwegian Mother; Father and Child Cohort study; MoBa
MeSH headings : Child; Cohort Studies; Cross-Sectional Studies; Environmental Exposure; Environmental Pollutants; Female; Humans; Iodine; Norway; Phthalic Acids / toxicity; Phthalic Acids / urine; Pregnancy; Prospective Studies; Thyroid Gland / drug effects; Thyroid Gland / physiopathology
TL;DR: It is found that phthalate exposure is associated with thyroid function in mid-pregnancy among Norwegian women, and that iodine intake, which is essential for thyroid health, could influence some of these relationships. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: April 20, 2020

2020 journal article

Measurement of Novel, Drinking Water-Associated PFAS in Blood from Adults and Children in Wilmington, North Carolina

ENVIRONMENTAL HEALTH PERSPECTIVES, 128(7).

By: N. Kotlarz n, J. McCord*, D. Collier*, C. Lea*, M. Strynar*, A. Lindstrom*, A. Wilkie n, J. Islam n ...

MeSH headings : Adult; Alkanesulfonic Acids; Caprylates; Child; Drinking Water; Environmental Exposure / statistics & numerical data; Female; Fluorocarbons / analysis; Fluorocarbons / blood; Humans; Male; North Carolina; Nutrition Surveys; Rivers; Water Pollutants, Chemical / analysis
TL;DR: Poorly understood fluoroethers released into the Cape Fear River by a fluorochemical manufacturing facility were detected in blood samples from Wilmington, North Carolina, residents. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 24, 2020

2020 journal article

Prenatal pesticide exposure and respiratory health outcomes in the first year of life: Results from the infants' Environmental Health (ISA) study

INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH, 225.

By: A. Mora*, J. Hoppin n, L. Cordoba*, J. Cano*, M. Soto-Martinez*, B. Eskenazi*, C. Lindh*, B. Joode*

author keywords: Pesticides; Mancozeb; Respiratory outcomes; Infants; Costa Rica
MeSH headings : Adult; Environmental Pollutants / urine; Ethylenethiourea / metabolism; Female; Humans; Infant; Infant Health; Male; Maneb / urine; Maternal Exposure; Maternal-Fetal Exchange; Pesticides / urine; Pregnancy; Prenatal Exposure Delayed Effects; Respiratory Sounds; Respiratory Tract Infections / epidemiology; Young Adult; Zineb / urine
TL;DR: Exposure to mancozeb/ETU during the first half of pregnancy may be associated with respiratory outcomes in the first year of life, and null associations between other pesticide metabolites measured during pregnancy and respiratory outcomes are observed. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: April 14, 2020

2020 journal article

SPARSE BAYESIAN ADDITIVE NONPARAMETRIC REGRESSION WITH APPLICATION TO HEALTH EFFECTS OF PESTICIDES MIXTURES

STATISTICA SINICA, 30(1), 55–79.

By: R. Wei, B. Reich*, J. Hoppin* & S. Ghosal

author keywords: Additive nonparametric regression; Bayesian variable selection; continuous shrinkage prior; environmental epidemiology; posterior consistency
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 26, 2020

2019 journal article

An algorithm for quantitatively estimating non-occupational pesticide exposure intensity for spouses in the Agricultural Health Study

JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY, 29(3), 344–357.

By: N. Deziel*, L. Freeman*, J. Hoppin n, K. Thomas*, C. Lerro*, R. Jones*, C. Hines*, A. Blair* ...

MeSH headings : Adult; Agriculture; Algorithms; Environmental Exposure / analysis; Farmers; Female; Humans; Male; Pesticides / analysis; Spouses; Surveys and Questionnaires
TL;DR: A quantitative, active ingredient-specific algorithm for cumulative (adult, married lifetime) non-occupational pesticide exposure intensity for spouses of farmers who applied pesticides in the Agricultural Health Study (AHS) is developed and will facilitate improved etiologic analyses in the AHS spouses. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: May 6, 2019

2019 journal article

Animal production, insecticide use and self-reported symptoms and diagnoses of COPD, including chronic bronchitis, in the Agricultural Health Study

ENVIRONMENT INTERNATIONAL, 127, 764–772.

By: J. Rinsky*, D. Richardson*, K. Kreiss*, L. Nylander-French*, L. Freeman*, S. London*, P. Henneberger*, J. Hoppin n

author keywords: Epidemiology; Occupational health; Environmental health; Pesticide
MeSH headings : Adult; Animal Husbandry; Animals; Bronchitis, Chronic / epidemiology; Farmers; Female; Humans; Insecticides / toxicity; Logistic Models; Male; Middle Aged; Occupational Exposure; Odds Ratio; Prevalence; Pulmonary Disease, Chronic Obstructive / chemically induced; Pulmonary Disease, Chronic Obstructive / epidemiology; Risk Factors; United States / epidemiology
TL;DR: Animal production work, including insecticide use, was positively associated with chronic bronchitis symptoms; but not consistently with COPD diagnosis alone; the results support the need for further investigation into the role of animal production-related exposures in the etiology of COPD and better respiratory protection for agricultural workers. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 17, 2019

2019 journal article

Associations between access to healthcare, environmental quality, and end-stage renal disease survival time: Proportional-hazards models of over 1,000,000 people over 14 years

PLOS ONE, 14(3).

By: M. Kosnik n, D. Reif n, D. Lobdell*, T. Astell-Burt*, X. Feng*, J. Hader*, J. Hoppin n

Contributors: M. Kosnik n, D. Reif n, D. Lobdell*, T. Astell-Burt*, X. Feng*, J. Hader*, J. Hoppin n

Ed(s): W. Cheungpasitporn

MeSH headings : Adolescent; Adult; Aged; Air Pollution / adverse effects; Female; Health Services Accessibility; Humans; Kidney Failure, Chronic / epidemiology; Male; Middle Aged; Prevalence; Proportional Hazards Models; Risk Factors; Socioeconomic Factors; United States / epidemiology; Water Quality; Young Adult
TL;DR: The results demonstrate the importance of considering multiple factors when studying ESRD survival and future efforts should consider additional components of the broader environment. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 9, 2019

2018 journal article

Endotoxin enhances respiratory effects of phthalates in adults: Results from NHANES 2005-6

ENVIRONMENTAL RESEARCH, 162, 280–286.

By: P. Strassle*, L. Smit* & J. Hoppin n

author keywords: Allergy; Asthma; Wheeze; Dust endotoxin; Phthalates
MeSH headings : Adult; Asthma / chemically induced; Cross-Sectional Studies; Dust; Endotoxins / toxicity; Environmental Exposure; Humans; Nutrition Surveys; Phthalic Acids / toxicity; Respiratory Sounds / drug effects
TL;DR: The lack of an association between wheeze or asthma and phthalate when endotoxin exposure was low suggests that phthalates alone may not increase these symptoms, whereas this cross‐sectional study cannot address key temporal issues. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2018 journal article

Prenatal Phthalates, Maternal Thyroid Function, and Risk of Attention-Deficit Hyperactivity Disorder in the Norwegian Mother and Child Cohort

ENVIRONMENTAL HEALTH PERSPECTIVES, 126(5).

By: S. Engel*, G. Villanger*, R. Nethery*, C. Thomsen*, A. Sakhi*, S. Drover*, J. Hoppin n, P. Zeiner* ...

MeSH headings : Adult; Attention Deficit Disorder with Hyperactivity / epidemiology; Attention Deficit Disorder with Hyperactivity / urine; Case-Control Studies; Cohort Studies; Female; Humans; Male; Mothers; Phthalic Acids / urine; Pregnancy; Prenatal Exposure Delayed Effects; Surveys and Questionnaires; Thyroid Gland / physiology
TL;DR: In this population-based case–control study of clinical ADHD, maternal urinary concentrations of DEHP were monotonically associated with increased risk of ADHD. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2018 journal article

Sleep apnea and pesticide exposure in a study of US farmers

SLEEP HEALTH, 4(1), 20–26.

By: B. Baumert*, M. Carnes*, J. Hoppin n, C. Jackson*, D. Sandler*, L. Freeman*, P. Henneberger*, D. Umbach* ...

author keywords: Pesticides; Sleep apnea; Carbofuran; Carbamates; Sleep disorder breathing; Agriculture
MeSH headings : Carbofuran / adverse effects; Case-Control Studies; Farmers / statistics & numerical data; Humans; Male; Occupational Exposure / adverse effects; Pesticides / toxicity; Prospective Studies; Sleep Apnea Syndromes / chemically induced; Surveys and Questionnaires; United States / epidemiology
TL;DR: The results in a male agricultural population suggests that exposure to carbofuran is positively associated with sleep apnea, a pesticide canceled in the United States in 2009 for most agricultural purposes but persists in the environment and remains in use in some other countries. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2017 journal article

Assessing the Exposome with External Measures: Commentary on the State of the Science and Research Recommendations

Annual Review of Public Health, 38(1), 215–239.

author keywords: exposome; external exposures; geographic information systems; remote sensing; global positioning systems; smartphones
MeSH headings : Environmental Exposure / adverse effects; Epigenomics; Geographic Information Systems; Health Behavior; Humans; Life Style; Research
TL;DR: Major scientific and technological advances that inform external assessment of the exposome are described, including geographic information systems; remote sensing; global positioning system and geolocation technologies; portable and personal sensing; and self-reported questionnaire assessments, which increasingly rely on Internet-based platforms. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Assessing the Potential for Bias From Nonresponse to a Study Follow-up Interview: An Example From the Agricultural Health Study

American Journal of Epidemiology, 186(4), 395–404.

By: J. Rinsky n, D. Richardson n, S. Wing n, J. Beard n, M. Alavanja n, L. Beane Freeman*, H. Chen n, P. Henneberger n ...

author keywords: attrition; epidemiologic methods; inverse probability weights; loss to follow-up; occupational/environmental epidemiology; prospective studies; selection bias
MeSH headings : Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / etiology; Agricultural Workers' Diseases / prevention & control; Bias; Cause of Death; Epidemiologic Research Design; Farmers / statistics & numerical data; Female; Follow-Up Studies; Humans; Interviews as Topic; Iowa / epidemiology; Lost to Follow-Up; Male; Middle Aged; Neoplasms / epidemiology; North Carolina; Odds Ratio; Prospective Studies; Smoking / epidemiology
TL;DR: This example provides a demonstration of investigating the influence of attrition in cohort studies using information that has been self-reported after enrollment, and the ability of inverse probability weighting (IPW) to reduce bias. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Early-life farm exposures and adult asthma and atopy in the Agricultural Lung Health Study

Journal of Allergy and Clinical Immunology, 140(1), 249–256.e14.

By: J. House*, A. Wyss*, J. Hoppin n, M. Richards*, S. Long*, D. Umbach*, P. Henneberger*, B. Freeman ...

Contributors: J. House*, A. Wyss*, J. Hoppin n, M. Richards*, S. Long*, D. Umbach*, P. Henneberger*, L. Beane Freeman ...

author keywords: Agriculture; agricultural workers' diseases; allergy and immunology; asthma; hygiene hypothesis; IgE; prenatal exposure delayed effects
MeSH headings : Aged; Asthma / epidemiology; Case-Control Studies; Environmental Exposure; Farms; Female; Humans; Hypersensitivity, Immediate / blood; Hypersensitivity, Immediate / epidemiology; Immunoglobulin E / blood; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Odds Ratio; Pulmonary Disease, Chronic Obstructive / epidemiology; Smoking / epidemiology
TL;DR: In a large US farming population, early‐life farm exposures, particularly maternal farming activities while pregnant, were strongly associated with reduced risk of atopy in adults, suggesting that protective associations of early‐ life farming exposures on atopy endure across the life course. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2017 journal article

House Dust Endotoxin Levels Are Associated with Adult Asthma in a U.S. Farming Population

Annals of the American Thoracic Society, 14(3), 324–331.

By: M. Carnes, J. Hoppin n, N. Metwali*, A. Wyss, J. Hankinson, E. O’Connell*, M. Richards*, S. Long* ...

author keywords: pulmonary function; atopy; wheeze; CD14; TLR4
MeSH headings : Aged; Agriculture / statistics & numerical data; Asthma / epidemiology; Asthma / genetics; Case-Control Studies; Dust / analysis; Endotoxins / analysis; Environmental Exposure / adverse effects; Female; Gene-Environment Interaction; Humans; Lipopolysaccharide Receptors / genetics; Logistic Models; Male; Middle Aged; Odds Ratio; Respiratory Sounds; Surveys and Questionnaires; Toll-Like Receptor 4 / genetics; United States / epidemiology
TL;DR: House dust endotoxin was associated with current atopic and nonatopic asthma in a U.S. farming population and was associatedwith lower pulmonary function in patients with asthma, and the degree of the association with asthma depended on early‐life farm exposures. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

House Dust Endotoxin and Periphera lLeukocyte Counts: Results from Two Large Epidemiologic Studies

ENVIRONMENTAL HEALTH PERSPECTIVES, 125(5).

By: M. Fessler*, M. Carnes*, P. Salo*, J. Wilkerson*, R. Cohn*, D. King*, J. Hoppin n, D. Sandler* ...

MeSH headings : Asthma / epidemiology; Dust / analysis; Endotoxins / adverse effects; Endotoxins / analysis; Female; Humans; Leukocyte Count; Linear Models; Male; Nutrition Surveys; Pulmonary Disease, Chronic Obstructive / epidemiology; Toll-Like Receptor 4 / genetics
TL;DR: There is a statistically significant, positive association between endotoxin concentration and total leukocyte number in the National Health and Nutrition Examination Survey 2005–2006 and the Agricultural Lung Health Study (ALHS), the first report of an association between house dust endotoxin and leukocytes count in a national survey. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2017 journal article

Insecticide Use and Breast Cancer Riskamong Farmers' Wives in the Agricultural Health Study

ENVIRONMENTAL HEALTH PERSPECTIVES, 125(9).

By: L. Engel*, E. Werder*, J. Satagopan*, A. Blair*, J. Hoppin n, S. Koutros*, C. Lerro*, D. Sandler* ...

MeSH headings : Adult; Aged; Agriculture; Agrochemicals / metabolism; Agrochemicals / toxicity; Breast Neoplasms / epidemiology; Farmers; Female; Humans; Incidence; Insecticides / metabolism; Insecticides / toxicity; Middle Aged; Occupational Exposure / statistics & numerical data; Organophosphates / metabolism; Organophosphates / toxicity
TL;DR: Use of several organophosphate insecticides was associated with elevated breast cancer risk among wives of pesticide applicators (farmers), but associations for the women’s and husbands’ use of these insecticides showed limited concordance. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2017 journal article

Occupational Exposure to Pesticides and the Incidence of Lung Cancer in the Agricultural Health Study

Environmental Health Perspectives, 125(4), 544–551.

By: M. Bonner*, L. Freeman*, J. Hoppin n, S. Koutros*, D. Sandler*, C. Lynch*, C. Hines*, K. Thomas* ...

MeSH headings : Agricultural Workers' Diseases / epidemiology; Agriculture; Humans; Incidence; Iowa / epidemiology; Lung Neoplasms / epidemiology; North Carolina / epidemiology; Occupational Exposure / statistics & numerical data; Pesticides; Proportional Hazards Models; Prospective Studies
TL;DR: An association between chlorimuron ethyl, a herbicide introduced in 1986, and lung cancer that has not been previously reported is found. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Organic Food in the Diet: Exposure and Health Implications

Annual Review of Public Health, 38(1), 295–313.

By: A. Brantsæter*, T. Ydersbond*, J. Hoppin n, M. Haugen* & H. Meltzer*

author keywords: organic food; organic vegetables; naturalness; compositional differences; health effects
MeSH headings : Agriculture / methods; Diet; Food; Food Contamination / prevention & control; Food, Organic; Humans; Nutritive Value
TL;DR: This review provides an update on market data and consumer preferences for organic food and summarizes the scientific evidence for compositional differences and health benefits of organic compared with conventionally produced food. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Organic solvent exposure and depressive symptoms among licensed pesticide applicators in the Agricultural Health Study

International Archives of Occupational and Environmental Health, 90(8), 849–857.

By: M. Siegel*, S. Starks*, W. Sanderson*, F. Kamel*, J. Hoppin* & F. Gerr*

author keywords: Farmers; Organic solvent exposure; Depressive symptoms; CES-D; Epidemiology
MeSH headings : Aged; Agriculture; Depression / epidemiology; Humans; Iowa; Male; Middle Aged; North Carolina; Occupational Exposure / adverse effects; Organic Chemicals / adverse effects; Pesticides; Risk Factors; Solvents / adverse effects; Surveys and Questionnaires
TL;DR: Efforts to limit exposure to organic solvents may reduce the risk of depressive symptoms among farmers after associations between questionnaire-based metrics of organic solvent exposure and depressive symptoms were examined. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 17, 2019

2017 journal article

Pesticides are Associated with Allergic and Non-Allergic Wheeze among Male Farmers

Environmental Health Perspectives, 125(4), 535–543.

By: J. Hoppin n, D. Umbach*, S. Long*, S. London*, P. Henneberger*, A. Blair*, M. Alavanja*, L. Freeman*, D. Sandler*

MeSH headings : Adult; Agricultural Workers' Diseases / epidemiology; Agriculture; Farmers; Humans; Iowa / epidemiology; Male; North Carolina / epidemiology; Occupational Exposure / statistics & numerical data; Pesticides; Prospective Studies; Respiratory Sounds
TL;DR: Evidence is seen of an exposure–response relationship for several pesticides including the commonly used herbicides 2,4-D and glyphosate, the insecticides permethrin and carbaryl, and the rodenticide warfarin, which are commonly used in agricultural and residential settings with adverse respiratory effects. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: NC State University Libraries, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Raw milk consumption and other early-life farm exposures and adult pulmonary function in the Agricultural Lung Health Study

Thorax, 73(3), 279–282.

By: A. Wyss*, J. House n, J. Hoppin n, M. Richards*, J. Hankinson, S. Long*, P. Henneberger*, L. Beane Freeman* ...

Contributors: A. Wyss*, J. House n, J. Hoppin n, M. Richards*, J. Hankinson, S. Long*, P. Henneberger*, L. Beane Freeman* ...

author keywords: COPD epidemiology; Asthma Epidemiology; Allergic lung disease; Occupational Lung Disease; Respiratory Measurement
MeSH headings : Adult; Aged; Agriculture; Animals; Case-Control Studies; Child; Child, Preschool; Environmental Exposure; Farms / statistics & numerical data; Female; Humans; Lung / physiopathology; Male; Middle Aged; Milk / physiology; Prospective Studies; Respiratory Physiological Phenomena; Spirometry / methods; United States
TL;DR: A novel association between raw milk consumption and higher pulmonary function that lasts into older adulthood is reported and did not find appreciable associations with other early-life farming exposures. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2017 journal article

Relative Contributions of Agricultural Drift, Para-Occupational, and Residential Use Exposure Pathways to House Dust Pesticide Concentrations: Meta-Regression of Published Data

Environmental Health Perspectives, 125(3), 296–305.

By: N. Deziel*, L. Freeman*, B. Graubard*, R. Jones*, J. Hoppin n, K. Thomas*, C. Hines*, A. Blair* ...

MeSH headings : Agriculture; Air Pollutants / analysis; Air Pollution, Indoor / statistics & numerical data; Dust / analysis; Environmental Exposure / statistics & numerical data; Environmental Monitoring; Housing / statistics & numerical data; Humans; Occupational Exposure; Pesticides / analysis
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Advancing Exposure Science through Chemical Data Curation and Integration in the Comparative Toxicogenomics Database

Environmental Health Perspectives, 124(10), 1592–1599.

By: C. Grondin n, A. Davis n, T. Wiegers n, B. King*, J. Wiegers n, D. Reif n, J. Hoppin n, C. Mattingly n

Contributors: C. Grondin n, A. Davis n, T. Wiegers n, B. King*, J. Wiegers n, D. Reif n, J. Hoppin n, C. Mattingly n

TL;DR: Curation and integration of exposure data within the CTD provides researchers with new opportunities to correlate exposures with human health outcomes, to identify underlying potential molecular mechanisms, and to improve understanding about the exposome. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2016 journal article

Greater Coronary Heart Disease Risk With Lower Intensity and Longer Duration Smoking Compared With Higher Intensity and Shorter Duration Smoking: Congruent Results Across Diverse Cohorts

Nicotine & Tobacco Research, 19(7), ntw290.

By: J. Lubin*, D. Albanes*, J. Hoppin n, H. Chen*, C. Lerro*, S. Weinstein*, D. Sandler*, L. Beane Freeman*

MeSH headings : Aged; Cohort Studies; Coronary Disease / epidemiology; Coronary Disease / mortality; Double-Blind Method; Finland / epidemiology; Humans; Male; Middle Aged; Risk Factors; Smoking / epidemiology; Smoking Cessation / methods; Time Factors; Tobacco Products / statistics & numerical data
TL;DR: In inverse smoking intensity effects in multiple cohorts with differing smoking patterns and other characteristics are observed, suggesting a common underlying phenomenon that offers clues to better understanding biological mechanisms and reinforces the importance of cessation rather than smoking less to reduce CHD risk. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

High pesticide exposure events and DNA methylation among pesticide applicators in the agricultural health study

Environmental and Molecular Mutagenesis, 58(1), 19–29.

By: J. Rusiecki*, L. Beane Freeman*, M. Bonner*, M. Alexander*, L. Chen*, G. Andreotti*, K. Barry*, L. Moore* ...

author keywords: DNA methylation; pesticides; exposure; Agricultural Health Study; epigenetics
MeSH headings : Air Pollutants, Occupational / toxicity; Antigens, CD; Cadherins / genetics; DNA / blood; DNA Methylation / drug effects; DNA Methylation / genetics; DNA Modification Methylases / genetics; DNA Repair Enzymes / genetics; Farmers; Glutathione S-Transferase pi / genetics; Humans; Iowa; Male; North Carolina; Occupational Exposure / adverse effects; Occupational Exposure / analysis; Occupational Health; Pesticides / toxicity; Promoter Regions, Genetic; Prospective Studies; Surveys and Questionnaires; Tumor Suppressor Proteins / genetics
TL;DR: Evaluated association between experiencing unusually high pesticide exposure events (HPEEs) and DNAm among pesticide applicators in the Agricultural Health Study, a prospective study of applicators from Iowa and North Carolina found non‐specific HPEEs may contribute to increasedDNAm in GSTp1, and in some groups, reduced DNAm in MGMT and LINE‐1. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Organic Food Consumption during Pregnancy and Hypospadias and Cryptorchidism at Birth: The Norwegian Mother and Child Cohort Study (MoBa)

Environmental Health Perspectives, 124(3), 357–364.

By: A. Brantsæter*, H. Torjusen*, H. Meltzer*, E. Papadopoulou*, J. Hoppin n, J. Alexander*, G. Lieblein*, G. Roos ...

MeSH headings : Adolescent; Adult; Cohort Studies; Cryptorchidism / epidemiology; Diet; Female; Food, Organic; Humans; Hypospadias / epidemiology; Infant, Newborn; Male; Maternal Exposure / adverse effects; Norway / epidemiology; Pregnancy; Prospective Studies; Risk Factors
TL;DR: Consumption of organically produced foods during pregnancy was associated with a lower prevalence of hypospadias in the Norwegian Mother and Child Cohort Study population, and replication in other study populations is required. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Pesticide exposure and neurodevelopment in children aged 6–9 years from Talamanca, Costa Rica

Cortex, 85, 137–150.

By: B. van Wendel de Joode*, A. Mora*, C. Lindh*, D. Hernández-Bonilla, L. Córdoba*, C. Wesseling*, J. Hoppin n, D. Mergler*

author keywords: Pesticides; Children; Environmental exposure; Neurobehavioral effects; Biomarkers
MeSH headings : Benzoates / urine; Central Nervous System / drug effects; Central Nervous System / growth & development; Child; Child Behavior; Chlorpyrifos / urine; Costa Rica; Cross-Sectional Studies; Female; Humans; Male; Maneb / urine; Pesticides / urine; Pyridones / urine; Zineb / urine
TL;DR: The findings indicate that children living near banana and plantain plantations are exposed to pesticides that may affect their neurodevelopment, which for certain domains may differ between boys and girls. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Response to “Comment on ‘Rheumatoid Arthritis in Agricultural Health Study Spouses: Associations with Pesticides and Other Farm Exposures’”

Response to “Comment on ‘Rheumatoid Arthritis in Agricultural Health Study Spouses: Associations with Pesticides and Other Farm Exposures.’” Environmental Health Perspectives, 124(11), A197–A197.

MeSH headings : Agricultural Workers' Diseases; Agriculture; Arthritis, Rheumatoid; Farms; Humans; Occupational Exposure; Pesticides; Spouses
TL;DR: It is important to note, however, that it is unlikely that metals exposure accounts for the other observed pesticide associations in the authors' study, including those with glyphosate and DDT. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Rheumatoid Arthritis in Agricultural Health Study Spouses: Associations with Pesticides and Other Farm Exposures

Environmental Health Perspectives, 124(11), 1728–1734.

By: C. Parks*, J. Hoppin n, A. De Roos*, K. Costenbader*, M. Alavanja* & D. Sandler*

MeSH headings : Arthritis, Rheumatoid / epidemiology; Cohort Studies; Environmental Exposure; Environmental Pollutants / toxicity; Farmers; Female; Fertilizers / toxicity; Humans; Pesticides / toxicity; Solvents / toxicity; Spouses
TL;DR: It is suggested that specific agricultural pesticides, solvents, and chemical fertilizers may increase the risk of RA in women, while exposures involving animal contact may be protective. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Urinary Concentrations of Phthalate Metabolites and Bisphenol A and Associations with Follicular-Phase Length, Luteal-Phase Length, Fecundability, and Early Pregnancy Loss

Environmental Health Perspectives, 124(3), 321–328.

By: A. Jukic*, A. Calafat*, D. McConnaughey*, M. Longnecker*, J. Hoppin n, C. Weinberg*, A. Wilcox*, D. Baird* ...

MeSH headings : Abortion, Spontaneous / chemically induced; Abortion, Spontaneous / urine; Adult; Benzhydryl Compounds / toxicity; Benzhydryl Compounds / urine; Environmental Pollutants / toxicity; Environmental Pollutants / urine; Female; Fertility / drug effects; Follicular Phase / drug effects; Humans; Luteal Phase / drug effects; Phenols / toxicity; Phenols / urine; Phthalic Acids / toxicity; Phthalic Acids / urine; Pregnancy; Pregnancy Trimester, First
TL;DR: Menstrual cycle–specific estimates of urinary BPA and phthalate metabolites were not associated with detrimental alterations in follicular-phase length, time to pregnancy, or early pregnancy loss, and in fact, DEHP [di(2-ethylhexyl)phthalate] metabolites and ΣDEHP were associated with reduced early loss. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 17, 2019

2016 journal article

Urinary concentrations of phthalate metabolites and bisphenol A and associations with follicular-phase length, luteal-phase length, fecundability, and early pregnancy loss

Environmental Health Perspectives, 124(3), 321–328.

By: A. Jukic, A. Calafat, D. McConnaughey, M. Longnecker, J. Hoppin, C. Weinberg, A. Wilcox, D. Baird

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Use of Dieselized Farm Equipment and Incident Lung Cancer: Findings from the Agricultural Health Study Cohort

Environmental Health Perspectives, 124(5), 611–618.

By: S. Tual*, D. Silverman*, S. Koutros*, A. Blair*, D. Sandler*, P. Lebailly*, G. Andreotti*, J. Hoppin n, L. Freeman*

MeSH headings : Agricultural Workers' Diseases / epidemiology; Agriculture / statistics & numerical data; Farmers; Iowa / epidemiology; Lung Neoplasms / epidemiology; North Carolina / epidemiology; Occupational Exposure / statistics & numerical data; Vehicle Emissions
TL;DR: Preliminary evidence of an increased risk of lung adenocarcinoma among daily drivers of diesel tractors is provided and it is suggested that exposure to endotoxins may modify the impact of diesel exposure on lung cancer risk. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

A Review of Nonoccupational Pathways for Pesticide Exposure in Women Living in Agricultural Areas

Environmental Health Perspectives, 123(6), 515–524.

By: N. Deziel*, M. Friesen*, J. Hoppin n, C. Hines*, K. Thomas* & L. Freeman*

MeSH headings : Agriculture; Environmental Exposure; Environmental Pollutants / metabolism; Female; Humans; North America; Pesticides / metabolism
TL;DR: An improved understanding of nonoccupational pesticide exposure pathways in women living in agricultural areas is critical for studying health effects in women and for designing effective exposure-reduction strategies. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Associations of Ozone and PM2.5 Concentrations With Parkinsonʼs Disease Among Participants in the Agricultural Health Study

Journal of Occupational and Environmental Medicine, 57(5), 509–517.

By: E. Kirrane*, C. Bowman*, J. Davis*, J. Hoppin*, A. Blair*, H. Chen*, M. Patel*, D. Sandler* ...

MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agriculture; Air Pollutants, Occupational / adverse effects; Air Pollutants, Occupational / analysis; Air Pollution / adverse effects; Air Pollution / analysis; Child; Farmers; Female; Follow-Up Studies; Humans; Iowa; Logistic Models; Male; Middle Aged; North Carolina; Occupational Diseases / etiology; Occupational Exposure / adverse effects; Occupational Exposure / analysis; Ozone / adverse effects; Ozone / analysis; Parkinson Disease / etiology; Particulate Matter / adverse effects; Particulate Matter / analysis; Young Adult
TL;DR: The plausibility of an effect of ambient concentrations of these pollutants on Parkinson's disease risk is supported by experimental data demonstrating damage to dopaminergic neurons at relevant concentrations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020

2015 journal article

Cancer incidence and metolachlor use in the Agricultural Health Study: An update

International Journal of Cancer, 137(11), 2630–2643.

By: S. Silver*, S. Bertke*, C. Hines*, M. Alavanja*, J. Hoppin n, J. Lubin*, J. Rusiecki*, D. Sandler*, L. Beane Freeman*

author keywords: cancer; epidemiology; pesticide; occupation
MeSH headings : Acetamides / toxicity; Aged; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Carcinogens / toxicity; Cohort Studies; Female; Herbicides / toxicity; Humans; Incidence; Iowa / epidemiology; Male; Middle Aged; Neoplasms / epidemiology; North Carolina / epidemiology; Occupational Exposure / adverse effects; Prospective Studies
TL;DR: A suggestion of an association between metolachlor and liver cancer among pesticide applicators is a novel finding and echoes observation of increased liver neoplasms in some animal studies, however, the findings for both liver cancer and follicular cell lymphoma warrant follow‐up to better differentiate effects of metolchlor use from other factors. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma

Nature Communications, 6(1).

By: C. Igartua*, R. Myers*, R. Mathias*, M. Pino-Yanes*, C. Eng*, P. Graves*, A. Levin*, B. Del-Rio-Navarro* ...

MeSH headings : Asthma / genetics; Carrier Proteins / genetics; Female; Genetic Predisposition to Disease / genetics; Genome-Wide Association Study / methods; Humans; Linkage Disequilibrium / genetics; Male; Membrane Proteins / genetics; Neoplasm Proteins / genetics
TL;DR: The results suggest that associations with rare and low-frequency variants are ethnic specific and not likely to explain a significant proportion of the ‘missing heritability’ of asthma. (via Semantic Scholar)
Source: Crossref
Added: January 5, 2020

2015 journal article

Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma

Nature Communications, 6.

By: C. Igartua, R. Myers, R. Mathias, M. Pino-Yanes, C. Eng, P. Graves, A. Levin, B. Del-Rio-Navarro ...

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Farm Characteristics, Allergy Symptoms, and Risk of Non-Hodgkin Lymphoid Neoplasms in the Agricultural Health Study

Cancer Epidemiology Biomarkers & Prevention, 24(3), 587–594.

By: J. Hofmann*, J. Hoppin n, C. Lynch*, J. Poole*, M. Purdue*, A. Blair*, M. Alavanja*, L. Beane Freeman*

MeSH headings : Adult; Aged; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / etiology; Agricultural Workers' Diseases / immunology; Cohort Studies; Farmers / statistics & numerical data; Female; Humans; Hypersensitivity / epidemiology; Hypersensitivity / etiology; Hypersensitivity / immunology; Lymphoma, Non-Hodgkin / epidemiology; Lymphoma, Non-Hodgkin / etiology; Lymphoma, Non-Hodgkin / immunology; Male; Middle Aged; North Carolina / epidemiology; Prospective Studies; Risk Factors
TL;DR: Both the reduced risk of NHL among those with allergy symptoms and specific farm exposures in adulthood, and the increased risk among those who grew up on a farm suggest that the host immune response to agricultural allergens may influence NHL development. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

IARC Monographs: 40 Years of Evaluating Carcinogenic Hazards to Humans

Environmental Health Perspectives, 123(6), 507–514.

By: N. Pearce*, A. Blair*, P. Vineis*, W. Ahrens*, A. Andersen*, J. Anto*, B. Armstrong*, A. Baccarelli* ...

MeSH headings : Biomedical Research; Carcinogens, Environmental; Humans; International Agencies / organization & administration; Neoplasms; Public Health; Publications
TL;DR: Criticism of the IARC classification process are unconvincing, the procedures employed by IARC to assemble Working Groups of scientists from the various disciplines and the techniques followed to review the literature and perform hazard assessment of various agents provide a balanced evaluation and an appropriate indication of the weight of the evidence. (via Semantic Scholar)
Source: Crossref
Added: January 5, 2020

2015 journal article

IARC monographs: 40 years of evaluating carcinogenic hazards to humans

Environmental Health Perspectives, 123(6), 507–514.

Jane Hoppin

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Incidence of solid tumours among pesticide applicators exposed to the organophosphate insecticide diazinon in the Agricultural Health Study: an updated analysis

Occupational and Environmental Medicine, 72(7), 496–503.

By: R. Jones*, F. Barone-Adesi*, S. Koutros*, C. Lerro*, A. Blair*, J. Lubin*, S. Heltshe*, J. Hoppin n ...

MeSH headings : Adult; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / etiology; Agriculture; Diazinon / adverse effects; Humans; Incidence; Iowa / epidemiology; Kidney Neoplasms / epidemiology; Kidney Neoplasms / etiology; Lung Neoplasms / epidemiology; Lung Neoplasms / etiology; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Organophosphorus Compounds / adverse effects; Pesticides / adverse effects; Prospective Studies; Prostatic Neoplasms / epidemiology; Prostatic Neoplasms / etiology
TL;DR: The authors' updated evaluation of diazinon provides additional evidence of an association with lung cancer risk and newly identified links to kidney cancer and associations with aggressive prostate cancer require further evaluation. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Investing in prospective cohorts for etiologic study of occupational exposures

American Journal of Industrial Medicine, 58(2), 113–122.

By: A. Blair*, C. Hines*, K. Thomas*, M. Alavanja*, L. Freeman*, J. Hoppin n, F. Kamel*, C. Lynch* ...

author keywords: prospective cohorts; agricultural exposures; occupational epidemiology
MeSH headings : Agricultural Workers' Diseases / etiology; Epidemiologic Research Design; Humans; Occupational Exposure / analysis; Occupational Medicine; Prospective Studies
TL;DR: Experience using this design to study agricultural workers to identify conditions that might foster use of prospective cohorts to study other occupational settings to investigate high priority, occupational exposures. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Opinions of clinical veterinarians at a US veterinary teaching hospital regarding antimicrobial use and antimicrobial-resistant infections

Journal of the American Veterinary Medical Association, 247(8), 938–944.

By: M. Jacob*, J. Hoppin*, N. Steers*, J. Davis*, G. Davidson*, B. Hansen, K. Lunn*, K. Murphy, M. Papich*

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Bacteria / drug effects; Bacterial Infections / microbiology; Bacterial Infections / veterinary; Cross-Sectional Studies; Data Collection; Drug Resistance, Bacterial; Education, Veterinary; Female; Hospitals, Animal; Humans; Male; Professional Practice; Schools, Veterinary; United States; Veterinarians
TL;DR: Findings indicated that veterinarians at this teaching hospital were concerned about antimicrobial resistance, thought antimicrobials were overprescribed, and supported restricting use of certain antimicrobial classes in companion animals. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Organophosphate insecticide use and cancer incidence among spouses of pesticide applicators in the Agricultural Health Study

Occupational and Environmental Medicine, 72(10), 736–744.

By: C. Lerro*, S. Koutros*, G. Andreotti*, M. Friesen*, M. Alavanja*, A. Blair*, J. Hoppin n, D. Sandler* ...

MeSH headings : Adult; Age Distribution; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Cohort Studies; Diazinon / adverse effects; Female; Humans; Incidence; Insecticides / adverse effects; Iowa / epidemiology; Male; Middle Aged; Neoplasms / chemically induced; Neoplasms / epidemiology; North Carolina / epidemiology; Occupational Exposure / adverse effects; Occupational Exposure / statistics & numerical data; Organophosphates / adverse effects; Retrospective Studies; Risk Assessment; Spouses / statistics & numerical data; Survival Rate; Young Adult
TL;DR: This study represents the first comprehensive analysis of OP use and cancer risk among women, suggesting potential for hormonally-mediated effects. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Pesticide Use and Relative Leukocyte Telomere Length in the Agricultural Health Study

PLOS ONE, 10(7), e0133382.

By: G. Andreotti*, J. Hoppin n, L. Hou*, S. Koutros*, S. Gadalla*, S. Savage*, J. Lubin*, A. Blair* ...

Ed(s): T. Nawrot

MeSH headings : Acetamides / poisoning; Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / diagnosis; Agricultural Workers' Diseases / genetics; Health Occupations / statistics & numerical data; Humans; Iowa; Leukocytes / drug effects; Leukocytes / metabolism; Malathion; Male; Middle Aged; North Carolina; Occupational Exposure / analysis; Organophosphate Poisoning / diagnosis; Organophosphate Poisoning / genetics; Pesticides / poisoning; Prospective Studies; Surveys and Questionnaires; Telomere / drug effects; Telomere / genetics; Telomere Homeostasis / drug effects; Telomere Shortening / drug effects
TL;DR: Ass associations between occupational pesticide use reported at three time points and relative telomere length (RTL) in the Agricultural Health Study are examined, suggesting that leukocyte TL may be impacted by cumulative use and recent use of certain pesticides. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Pesticide exposure and end-stage renal disease risk among wives of pesticide applicators in the Agricultural Health Study

Environmental Research, 143, 198–210.

By: J. Lebov*, L. Engel*, D. Richardson*, S. Hogan*, D. Sandler* & J. Hoppin n

author keywords: Pesticide exposure; End-stage renal disease; Farm women; Agricultural exposures
MeSH headings : Adolescent; Adult; Aged; Environmental Exposure / adverse effects; Environmental Exposure / analysis; Farmers / statistics & numerical data; Female; Humans; Incidence; Iowa / epidemiology; Kidney Failure, Chronic / chemically induced; Kidney Failure, Chronic / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Pesticides / analysis; Pesticides / toxicity; Proportional Hazards Models; Prospective Studies; Risk Factors; Spouses / statistics & numerical data; Surveys and Questionnaires; Time Factors; Young Adult
TL;DR: ESRD may be associated with direct and/or indirect exposure to pesticides among farm women and future studies should evaluate indirect exposure risk among other rural populations. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Pesticide use and risk of end-stage renal disease among licensed pesticide applicators in the Agricultural Health Study

Occupational and Environmental Medicine, 73(1), 3–12.

By: J. Lebov*, L. Engel*, D. Richardson*, S. Hogan*, J. Hoppin n & D. Sandler*

MeSH headings : Agriculture; Herbicides / adverse effects; Humans; Incidence; Iowa; Kidney Failure, Chronic / etiology; Male; North Carolina; Occupational Diseases / etiology; Occupational Exposure / adverse effects; Occupations; Pesticides / adverse effects; Proportional Hazards Models; Prospective Studies; Risk Factors
TL;DR: The findings support an association between ESRD and chronic exposure to specific pesticides, and suggest pesticide exposures resulting in medical visits may increase the risk of E SRD. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Protective glove use and hygiene habits modify the associations of specific pesticides with Parkinson's disease

Environment International, 75, 144–150.

By: M. Furlong*, C. Tanner*, S. Goldman*, G. Bhudhikanok*, A. Blair*, A. Chade*, K. Comyns*, J. Hoppin n ...

author keywords: Personal protective equipment; Parkinson's disease; Pesticides; Neurodegenerative diseases; Movement disorders
MeSH headings : Adult; Aged; Aged, 80 and over; Agriculture; Case-Control Studies; Female; Gloves, Protective / statistics & numerical data; Habits; Humans; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Occupational Exposure / prevention & control; Occupational Health; Paraquat; Parkinson Disease / epidemiology; Parkinson Disease / etiology; Permethrin; Pesticides; Risk; Rotenone; Surveys and Questionnaires; Trifluralin; Workplace
TL;DR: Although sample size was limited in the FAME study, protective glove use and hygiene practices appeared to be important modifiers of the association between pesticides and PD and may reduce risk of PD associated with certain pesticides. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Accuracy of residential geocoding in the Agricultural Health Study

International Journal of Health Geographics, 13(1), 37.

By: R. Jones*, C. DellaValle*, A. Flory*, A. Nordan*, J. Hoppin n, J. Hofmann*, H. Chen*, J. Giglierano* ...

author keywords: Geocoding; Positional error; Rural location; Environmental exposure assessment; Accuracy
MeSH headings : Agriculture / statistics & numerical data; Cohort Studies; Environmental Exposure / analysis; Environmental Exposure / statistics & numerical data; Female; Geographic Mapping; Health Status; Humans; Iowa / epidemiology; Male; North Carolina / epidemiology; Pesticides; Prospective Studies
TL;DR: It is suggested that where E911 locations are available, they offer an improvement upon address-matched geocodes for rural addresses, and that exposure misclassification resulting from positional error can be minimized when known coordinates are available to test alternative data and methods. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Association between Class III Obesity (BMI of 40–59 kg/m2) and Mortality: A Pooled Analysis of 20 Prospective Studies

PLoS Medicine, 11(7), e1001673.

Contributors: C. Kitahara*, A. Flint*, A. Gonzalez*, L. Bernstein*, M. Brotzman*, R. MacInnis*, S. Moore*, K. Robien* ...

Ed(s): K. Khaw

MeSH headings : Australia / epidemiology; Body Mass Index; Humans; Life Expectancy; Obesity / mortality; Prospective Studies; Risk Factors; Sweden / epidemiology; United States / epidemiology
TL;DR: In a pooled analysis of 20 prospective studies, Cari Kitahara and colleagues find that class III obesity is associated with excess rates of total mortality, particularly due to heart disease, cancer, and diabetes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2014 journal article

Dietary fat intake, pesticide use, and Parkinson's disease

Parkinsonism & Related Disorders, 20(1), 82–87.

By: F. Kamel*, S. Goldman*, D. Umbach*, H. Chen*, G. Richardson*, M. Barber*, C. Meng*, C. Marras* ...

Contributors: F. Kamel*, S. Goldman*, D. Umbach*, H. Chen*, G. Richardson*, M. Barber*, C. Meng*, C. Marras* ...

author keywords: Parkinson's disease; Dietary fat; Polyunsaturated fatty acids; Pesticides
MeSH headings : Adult; Aged; Aged, 80 and over; Case-Control Studies; Diet; Dietary Fats; Fatty Acids, Omega-3; Female; Humans; Male; Middle Aged; Parkinson Disease / epidemiology; Pesticides / adverse effects; Risk Factors
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2014 journal article

Is Helicobacter Pylori an endogenous source of diethyl phthalate in humans?

Environmental Research, 134, 402–404.

By: G. Hilton n & J. Hoppin n

author keywords: Diethyl phthalate; Monoethyl phthalate; Helicobacter pylori; NHANES; Microbiome
MeSH headings : Adolescent; Adult; Female; Helicobacter pylori / metabolism; Humans; Male; Middle Aged; Phthalic Acids / metabolism; Young Adult
TL;DR: Results suggest that HP may be an endogenous source of DEP in some populations, and MEP levels were higher in individuals with HP seropositivity, however the association differed by race. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Long-Term Exposure to Fine Particulate Matter: Association with Nonaccidental and Cardiovascular Mortality in the Agricultural Health Study Cohort

Environmental Health Perspectives, 122(6), 609–615.

MeSH headings : Adult; Agriculture / statistics & numerical data; Air Pollutants / analysis; Air Pollutants / toxicity; Cardiovascular Diseases / mortality; Cohort Studies; Environmental Exposure / analysis; Environmental Exposure / statistics & numerical data; Female; Humans; Iowa / epidemiology; Male; Mortality; North Carolina / epidemiology; Particulate Matter / analysis; Particulate Matter / toxicity; Risk Factors; Rural Population; Sex Factors
TL;DR: Positive associations were observed between ambient PM2.5 and cardiovascular mortality among men, and these associations were strongest among men who did not move from their enrollment address, while similar associations were not observed among women. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2014 journal article

Non-Hodgkin Lymphoma Risk and Insecticide, Fungicide and Fumigant Use in the Agricultural Health Study

PLoS ONE, 9(10), e109332.

By: M. Alavanja*, J. Hofmann*, C. Lynch*, C. Hines*, K. Barry*, J. Barker*, D. Buckman*, K. Thomas* ...

Ed(s): S. Akiba

MeSH headings : Adult; Aged; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Agriculture; Fungicides, Industrial / toxicity; Humans; Hydrocarbons, Chlorinated / toxicity; Insecticides / toxicity; Iowa; Leukemia, Lymphocytic, Chronic, B-Cell / chemically induced; Leukemia, Lymphocytic, Chronic, B-Cell / epidemiology; Leukemia, Lymphocytic, Chronic, B-Cell / pathology; Lymphoma, Non-Hodgkin / chemically induced; Lymphoma, Non-Hodgkin / epidemiology; Lymphoma, Non-Hodgkin / pathology; Middle Aged; Multiple Myeloma / chemically induced; Multiple Myeloma / epidemiology; Multiple Myeloma / pathology; North Carolina; Risk Factors
TL;DR: Findings are among the first to suggest links between DDT, lindane, permethrin, diazinon and terbufos with NHL subtypes, but not all members of any single class of pesticides were associated with an elevated risk of NHL or NHL sub types. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020

2014 journal article

Obesity and the cardiovascular health effects of fine particulate air pollution

Obesity, 22(7), 1580–1589.

By: S. Weichenthal*, J. Hoppin n & F. Reeves*

Contributors: S. Weichenthal*, J. Hoppin n & F. Reeves*

MeSH headings : Air Pollution / adverse effects; Air Pollution / statistics & numerical data; Cardiovascular Diseases / mortality; Causality; Cause of Death; Cohort Studies; Comorbidity; Environmental Monitoring / statistics & numerical data; Female; Humans; Longitudinal Studies; Male; Obesity / mortality; Particulate Matter / toxicity; Prospective Studies; Public Health; Weather
TL;DR: This review examines evidence related to the potential impact of obesity on the cardiovascular health effects of fine particulate air pollution (PM2.5). (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Peptidoglycan recognition protein genes and risk of Parkinson's disease

Movement Disorders, 29(9), 1171–1180.

By: S. Goldman*, F. Kamel*, G. Ross*, S. Jewell*, C. Marras*, J. Hoppin n, D. Umbach*, G. Bhudhikanok* ...

Contributors: S. Goldman*, F. Kamel*, G. Ross*, S. Jewell*, C. Marras*, J. Hoppin n, D. Umbach*, G. Bhudhikanok* ...

author keywords: Parkinson's disease; peptidoglycan; PGLYRP; microbiome; gut
MeSH headings : Adult; Aged; Aged, 80 and over; Carrier Proteins / genetics; Case-Control Studies; Female; Genetic Association Studies; Genetic Predisposition to Disease / genetics; Genotype; Humans; Logistic Models; Male; Microbiota / genetics; Middle Aged; Odds Ratio; Parkinson Disease / genetics; Polymorphism, Single Nucleotide / genetics
TL;DR: Common variants in PGLYRP genes are associated with PD risk in two independent studies and are consistent with hypotheses of a causative role for the gut microbiota and gastrointestinal immune response in PD. (via Semantic Scholar)
Sources: ORCID, NC State University Libraries, Crossref, NC State University Libraries
Added: August 6, 2018

2014 journal article

Perfluoroalkyl Substances During Pregnancy and Validated Preeclampsia Among Nulliparous Women in the Norwegian Mother and Child Cohort Study

American Journal of Epidemiology, 179(7), 824–833.

By: A. Starling, S. Engel, D. Richardson, D. Baird, L. Haug, A. Stuebe, K. Klungsoyr, Q. Harmon ...

Contributors: A. Starling, S. Engel, D. Richardson, D. Baird, L. Haug, A. Stuebe, K. Klungsøyr, Q. Harmon ...

author keywords: Norwegian Mother and Child Cohort Study; perfluoroalkyl substances; perfluorooctanoic acid; perfluorooctane sulfonate; perfluoroundecanoic acid; preeclampsia
MeSH headings : Adolescent; Adult; Alkanesulfonic Acids / blood; Caprylates / blood; Cohort Studies; Environmental Exposure / adverse effects; Environmental Exposure / analysis; Environmental Pollutants / adverse effects; Environmental Pollutants / blood; Fatty Acids / blood; Female; Fluorocarbons / blood; Humans; Norway; Parity; Pre-Eclampsia / blood; Pre-Eclampsia / etiology; Pregnancy; Proportional Hazards Models; Young Adult
TL;DR: The findings do not support an increased risk of preeclampsia among nulliparous Norwegian women with background levels of PFAS exposure, and an inverse association between preeClampsia and the highest quartile of perfluoroundecanoic acid concentration relative to the lowest quartile is found. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2014 journal article

Perfluoroalkyl substances and lipid concentrations in plasma during pregnancy among women in the Norwegian Mother and Child Cohort Study

Environment International, 62, 104–112.

By: A. Starling*, S. Engel*, K. Whitworth*, D. Richardson*, A. Stuebe*, J. Daniels*, L. Haug*, M. Eggesbø* ...

Contributors: A. Starling*, S. Engel*, K. Whitworth*, D. Richardson*, A. Stuebe*, J. Daniels*, L. Haug*, M. Eggesbø* ...

author keywords: The Norwegian Mother and Child Cohort Study MoBa; Perfluoroalkyl substances; Perfluorooctanoic acid; Perfluorooctane sulfonate
MeSH headings : Adult; Alkanesulfonic Acids / blood; Cholesterol / blood; Cohort Studies; Cross-Sectional Studies; Environmental Pollutants / blood; Female; Fluorocarbons / blood; Humans; Linear Models; Lipids / blood; Mothers; Norway
TL;DR: Plasma concentrations of PFASs were positively associated with HDL cholesterol, and PFOS was positivelyassociated with total cholesterol in this sample of pregnant Norwegian women, suggesting a mechanism by which PFAS exposure leads to certain adverse pregnancy outcomes, including preeclampsia. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2014 journal article

Pesticide Exposure and Depression among Male Private Pesticide Applicators in the Agricultural Health Study

Environmental Health Perspectives, 122(9), 984–991.

By: J. Beard*, D. Umbach*, J. Hoppin*, M. Richards*, M. Alavanja*, A. Blair*, D. Sandler, F. Kamel

MeSH headings : Adult; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Depression / chemically induced; Depression / epidemiology; Hazardous Substances / metabolism; Humans; Hydrocarbons, Chlorinated / metabolism; Iowa / epidemiology; Logistic Models; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / statistics & numerical data; Odds Ratio; Organophosphorus Compounds / metabolism; Pesticides / metabolism; Risk Factors; Young Adult
TL;DR: A positive association between pesticide exposure and depression among male private pesticide applicators in the Agricultural Health Study is supported, including associations with several specific pesticides. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020

2014 journal article

Pesticide use and incident diabetes among wives of farmers in the Agricultural Health Study

Occupational and Environmental Medicine, 71(9), 629–635.

By: A. Starling*, D. Umbach*, F. Kamel*, S. Long*, D. Sandler* & J. Hoppin n

Contributors: A. Starling*, D. Umbach*, F. Kamel*, S. Long*, D. Sandler* & J. Hoppin n

MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Diabetes Mellitus / epidemiology; Diabetes Mellitus / etiology; Female; Humans; Incidence; Iowa / epidemiology; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Organophosphates / toxicity; Pesticides / toxicity; Proportional Hazards Models; Spouses; Young Adult
TL;DR: Results are consistent with previous studies reporting an association between specific organochlorines and diabetes and add to growing evidence that certain organophosphates also may increase risk, though attenuated compared with separate models. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Prevalence of allergic sensitization in the United States: Results from the National Health and Nutrition Examination Survey (NHANES) 2005-2006

Journal of Allergy and Clinical Immunology, 134(2), 350–359.

By: P. Salo*, S. Arbes*, R. Jaramillo*, A. Calatroni*, C. Weir*, M. Sever*, J. Hoppin*, K. Rose* ...

Contributors: P. Salo*, S. Arbes Jr., R. Jaramillo*, A. Calatroni*, C. Weir*, M. Sever*, J. Hoppin*, K. Rose* ...

author keywords: Allergen; allergy; allergic sensitization; serum IgE
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Allergens / immunology; Child; Child, Preschool; Cross Reactions; Cross-Sectional Studies; Female; Food Hypersensitivity / blood; Food Hypersensitivity / epidemiology; Food Hypersensitivity / ethnology; Food Hypersensitivity / immunology; Humans; Immunoglobulin E / blood; Infant; Male; Middle Aged; Nutrition Surveys; Prevalence; Racial Groups; Respiratory Hypersensitivity / blood; Respiratory Hypersensitivity / epidemiology; Respiratory Hypersensitivity / ethnology; Respiratory Hypersensitivity / immunology; United States / epidemiology
TL;DR: The overall prevalence of allergic sensitization does not vary across US census regions, except in early life, although allergen-specific sensitization differs based on sociodemographic and regional factors. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2014 journal article

Reliability of triclosan measures in repeated urine samples from Norwegian pregnant women

Journal of Exposure Science & Environmental Epidemiology, 24(5), 517–521.

By: R. Bertelsen*, S. Engel*, T. Jusko*, A. Calafat*, J. Hoppin*, S. London*, M. Eggesbø*, H. Aase* ...

Contributors: R. Bertelsen*, S. Engel*, T. Jusko*, A. Calafat*, J. Hoppin*, S. London*, M. Eggesbø*, H. Aase* ...

author keywords: biomarkers; MoBa; intraclass correlation coefficient; pregnancy; reliability; triclosan
MeSH headings : Anti-Infective Agents, Local / urine; Female; Humans; Norway; Pregnancy; Reproducibility of Results; Triclosan / urine
TL;DR: The reliability of TCS concentrations in repeated urine samples from pregnant Norwegian women was reasonably good, suggesting a single urine sample can adequately represent TCS exposure during pregnancy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2014 journal article

Respiratory disease in United States farmers

Occupational and Environmental Medicine, 71(7), 484–491.

By: J. Hoppin n, D. Umbach*, S. Long*, J. Rinsky*, P. Henneberger*, P. Salo*, D. Zeldin*, S. London* ...

Contributors: J. Hoppin n, D. Umbach*, S. Long*, J. Rinsky*, P. Henneberger*, P. Salo*, D. Zeldin*, S. London* ...

MeSH headings : Adult; Aged; Aged, 80 and over; Agriculture; Air Pollutants / adverse effects; Asthma / epidemiology; Asthma / etiology; Cough / epidemiology; Cough / etiology; Female; Humans; Iowa / epidemiology; Male; Middle Aged; Mucus / metabolism; North Carolina / epidemiology; Nutrition Surveys; Occupational Diseases / epidemiology; Occupational Diseases / etiology; Occupational Exposure / adverse effects; Prevalence; Prospective Studies; Respiration Disorders / epidemiology; Respiration Disorders / etiology; Respiratory Sounds / etiology; Risk Factors; Sex Factors; Spouses; Young Adult
TL;DR: Findings suggest that farmers and their spouses have lower risk for adult-onset respiratory diseases compared with the general population, and potentially higher respiratory irritation as evidenced by increased respiratory symptoms. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Single-Nucleotide Polymorphism Data Support the General Unrelatedness of the Males in the Agricultural Health Study

Cancer Epidemiology Biomarkers & Prevention, 23(10), 2192–2195.

By: J. Jack n, A. Motsinger-Reif n, S. Koutros*, M. Alavanja*, L. Beane Freeman* & J. Hoppin n

MeSH headings : Agriculture; Case-Control Studies; Cohort Studies; Consanguinity; Gene-Environment Interaction; Humans; Male; Occupational Exposure; Polymorphism, Single Nucleotide; Principal Component Analysis; Research Design
TL;DR: This analysis rejects the hypothesis that individuals in the case–control study of prostate cancer exhibit cryptic relatedness, and these findings are important for all subsequent analyses of gene–environment interactions in the AHS. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

A-clustering: a novel method for the detection of co-regulated methylation regions, and regions associated with exposure

Bioinformatics, 29(22), 2884–2891.

Contributors: T. Sofer*, E. Schifano*, J. Hoppin*, L. Hou* & A. Baccarelli*

MeSH headings : Algorithms; Cluster Analysis; CpG Islands; DNA Methylation; Environmental Exposure; Humans
TL;DR: An analysis pipeline for high-dimensional methylation data in which CpG sites within regions identified by A-clustering are modeled as multivariate responses to environmental exposure using a generalized estimating equation approach that assumes exposure equally affects all sites in the cluster. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2013 journal article

Agricultural Exposures and Stroke Mortality in the Agricultural Health Study

Journal of Toxicology and Environmental Health, Part A, 76(13), 798–814.

By: J. Rinsky*, J. Hoppin*, A. Blair*, K. He*, L. Beane Freeman* & H. Chen*

Contributors: J. Rinsky*, J. Hoppin*, A. Blair*, K. He*, L. Beane Freeman* & H. Chen*

MeSH headings : Aged; Agricultural Workers' Diseases / etiology; Agricultural Workers' Diseases / mortality; Agriculture / statistics & numerical data; Female; Humans; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Pesticides / adverse effects; Proportional Hazards Models; Prospective Studies; Risk Factors; Spouses; Stroke / etiology; Stroke / mortality; Surveys and Questionnaires; Survival Rate
TL;DR: The authors evaluated associations between self-reported agricultural activities including pesticide use and handling of crops and stroke mortality among 51,603 male pesticide applicators enrolled in the Agricultural Health Study (AHS). (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2013 journal article

Arsenic Exposure and Incidence of Type 2 Diabetes in Southwestern American Indians

American Journal of Epidemiology, 177(9), 962–969.

By: N. Kim, C. Mason, R. Nelson, S. Afton, A. Essader, J. Medlin, K. Levine, J. Hoppin* ...

Contributors: N. Kim, C. Mason, R. Nelson, S. Afton, A. Essader, J. Medlin, K. Levine, J. Hoppin* ...

author keywords: arsenic; diabetes mellitus; type 2; incidence; Indians; North American; nested case-control studies
MeSH headings : Adult; Albuminuria / urine; Arizona / epidemiology; Arsenic / adverse effects; Arsenic / urine; Biomarkers / urine; Case-Control Studies; Creatinine / urine; Diabetes Mellitus, Type 2 / ethnology; Diabetes Mellitus, Type 2 / etiology; Diabetes Mellitus, Type 2 / urine; Drinking Water / chemistry; Environmental Exposure / adverse effects; Environmental Exposure / analysis; Female; Glucose Tolerance Test; Humans; Incidence; Indians, North American / statistics & numerical data; Logistic Models; Longitudinal Studies; Male; Odds Ratio; Prevalence; Water Pollutants, Chemical / adverse effects; Water Pollutants, Chemical / analysis
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2013 journal article

Association between Perfluoroalkyl substances and thyroid stimulating hormone among pregnant women: a cross-sectional study

Environmental Health, 12(1).

By: Y. Wang*, A. Starling*, L. Haug*, M. Eggesbo*, G. Becher*, C. Thomsen*, G. Travlos*, D. King* ...

Contributors: Y. Wang*, A. Starling*, L. Haug*, M. Eggesbo*, G. Becher*, C. Thomsen*, G. Travlos*, D. King* ...

author keywords: Perfluorinated alkyl substances; Thyroid stimulating hormone; Pregnant women; The Norwegian Mother and child cohort study; MoBa
MeSH headings : Adolescent; Adult; Alkanes / blood; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Environmental Exposure; Environmental Monitoring; Environmental Pollutants / blood; Female; Fluorocarbons / blood; Humans; Immunoassay; Linear Models; Norway; Odds Ratio; Pregnancy; Tandem Mass Spectrometry; Thyrotropin / blood; Young Adult
TL;DR: An association between PFOS and TSH in pregnant women is suggested that is small and may be of no clinical significance, and other PFASs were unrelated to TSH. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2013 journal article

Determinants of plasma concentrations of perfluoroalkyl substances in pregnant Norwegian women

Environment International, 54, 74–84.

By: A. Brantsæter*, K. Whitworth*, T. Ydersbond*, L. Haug*, M. Haugen*, H. Knutsen*, C. Thomsen*, H. Meltzer* ...

Contributors: A. Brantsæter*, K. Whitworth*, T. Ydersbond*, L. Haug*, M. Haugen*, H. Knutsen*, C. Thomsen*, H. Meltzer* ...

author keywords: Perfluoroalkyl substances; Reproductive history; Pregnancy; Dietary exposure
MeSH headings : Adult; Alkanesulfonic Acids / blood; Cohort Studies; Diet / statistics & numerical data; Environmental Pollutants / blood; Female; Fluorocarbons / blood; Humans; Maternal Exposure / statistics & numerical data; Norway; Pregnancy
TL;DR: Previous pregnancies and breastfeeding duration were the most important determinants of PFASs in this sample of pregnant women, and diet was a significant factor explaining up to 4% of the variance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2013 journal article

Exacerbation of symptoms in agricultural pesticide applicators with asthma

International Archives of Occupational and Environmental Health, 87(4), 423–432.

MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / etiology; Asthma, Occupational / epidemiology; Asthma, Occupational / etiology; Female; Humans; Male; Middle Aged; Occupational Exposure / adverse effects; Pesticides / adverse effects; Risk Factors; Severity of Illness Index; Surveys and Questionnaires; United States; Young Adult
TL;DR: The inverse associations with two pesticides and specific farm activities are consistent with the possibility that asthma cases prone to exacerbation may avoid exposures that trigger symptoms, and suggest that use of specific pesticides may contribute to exacerbate of asthma among individuals with allergies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2013 journal article

Genetic Susceptibility Loci, Pesticide Exposure and Prostate Cancer Risk

PLoS ONE, 8(4), e58195.

By: S. Koutros*, S. Berndt*, K. Hughes Barry*, G. Andreotti*, J. Hoppin*, D. Sandler*, M. Yeager*, L. Burdett* ...

Contributors: S. Koutros*, S. Berndt*, K. Hughes Barry*, G. Andreotti*, J. Hoppin*, D. Sandler*, M. Yeager*, L. Burdett* ...

Ed(s): M. Scheurer

MeSH headings : Adult; Aged; Aged, 80 and over; Case-Control Studies; Environmental Exposure; Gene-Environment Interaction; Genetic Loci; Genetic Predisposition to Disease; Genome-Wide Association Study; Humans; Male; Middle Aged; Neoplasm Grading; Neoplasm Staging; Odds Ratio; Pesticides / adverse effects; Polymorphism, Single Nucleotide; Prospective Studies; Prostatic Neoplasms / etiology; Prostatic Neoplasms / pathology; Risk; Young Adult
TL;DR: This study suggests known genetic susceptibility loci may modify the risk between pesticide use and prostate cancer. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2013 journal article

Hypothyroidism and Pesticide Use Among Male Private Pesticide Applicators in the Agricultural Health Study

Journal of Occupational and Environmental Medicine, 55(10), 1171–1178.

By: W. Goldner, D. Sandler, F. Yu, V. Shostrom, J. Hoppin*, F. Kamel, T. LeVan

Contributors: W. Goldner, D. Sandler, F. Yu, V. Shostrom, J. Hoppin*, F. Kamel, T. Levan

MeSH headings : Adult; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Agriculture; Humans; Hypothyroidism / chemically induced; Hypothyroidism / epidemiology; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / statistics & numerical data; Pesticides / adverse effects; Prospective Studies; Surveys and Questionnaires
TL;DR: There is an association between hypothyroidism and specific herbicides and insecticides in male applicators, similar to previous results for spouses. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2013 journal article

Joint effects between five identified risk variants, allergy, and autoimmune conditions on glioma risk

Cancer Causes & Control, 24(10), 1885–1891.

By: M. Safaeian*, P. Rajaraman*, P. Hartge*, M. Yeager*, M. Linet*, M. Butler*, A. Ruder*, M. Purdue* ...

Contributors: M. Safaeian*, P. Rajaraman*, P. Hartge*, M. Yeager*, M. Linet*, M. Butler*, A. Ruder*, M. Purdue* ...

author keywords: Single-nucleotide polymorphisms; Glioma; Allergies; Autoimmune conditions; Gene-environment interaction
MeSH headings : Aged; Autoimmune Diseases / epidemiology; Autoimmune Diseases / genetics; Autoimmune Diseases / immunology; Brain Neoplasms / epidemiology; Brain Neoplasms / genetics; Brain Neoplasms / immunology; Case-Control Studies; Female; Gene-Environment Interaction; Genetic Predisposition to Disease; Glioma / epidemiology; Glioma / genetics; Glioma / immunology; Humans; Hypersensitivity / epidemiology; Hypersensitivity / genetics; Hypersensitivity / immunology; Male; Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; United States / epidemiology
TL;DR: The results do not provide evidence that allergies or AIC modulate the association between the four GWAS-identified SNPs examined and risk of glioma. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2013 journal article

Lifetime Pesticide Use and Telomere Shortening among Male Pesticide Applicators in the Agricultural Health Study

Environmental Health Perspectives, 121(8), 919–924.

By: L. Hou*, G. Andreotti*, A. Baccarelli*, S. Savage*, J. Hoppin*, D. Sandler*, J. Barker, Z. Zhu* ...

Contributors: L. Hou*, G. Andreotti*, A. Baccarelli*, S. Savage*, J. Hoppin*, D. Sandler*, J. Barker, Z. Zhu* ...

author keywords: Agricultural Health Study; cancer-free subjects; occupational exposures; pesticides; telomere length
MeSH headings : Adult; Aged; Aged, 80 and over; Agriculture; DDT / toxicity; Humans; Iowa; Male; Middle Aged; Mouth Mucosa / chemistry; Mouth Mucosa / drug effects; North Carolina; Occupational Exposure; Pesticides / toxicity; Prospective Studies; Real-Time Polymerase Chain Reaction; Telomere Shortening / drug effects
TL;DR: Seven pesticides previously associated with cancer risk in the epidemiologic literature were inversely associated with RTL in buccal cell DNA among cancer-free pesticide applicators. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2013 journal article

Pesticide Exposure and Inherited Variants in Vitamin D Pathway Genes in Relation to Prostate Cancer

Cancer Epidemiology Biomarkers & Prevention, 22(9), 1557–1566.

By: S. Karami*, G. Andreotti*, S. Koutros*, K. Barry*, L. Moore*, S. Han*, J. Hoppin*, D. Sandler* ...

Contributors: S. Karami*, G. Andreotti*, S. Koutros*, K. Barry*, L. Moore*, S. Han*, J. Hoppin*, D. Sandler* ...

MeSH headings : Aged; Aged, 80 and over; Apoptosis / drug effects; Apoptosis / genetics; Case-Control Studies; Cell Growth Processes / drug effects; Cell Growth Processes / genetics; Cohort Studies; Genotype; Humans; Male; Middle Aged; Pesticides / poisoning; Polymorphism, Single Nucleotide; Prostatic Neoplasms / chemically induced; Prostatic Neoplasms / epidemiology; Prostatic Neoplasms / genetics; Risk Factors; Surveys and Questionnaires; United States / epidemiology; Vitamin D / genetics; Vitamin D / metabolism
TL;DR: Genetic variations in vitamin D pathway genes, particularly GC rs7041, an SNP previously linked to lower circulating vitamin D levels, modified pesticide associations with prostate cancer risk are examined. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2013 journal article

Pesticide exposure and self-reported incident depression among wives in the Agricultural Health Study

Environmental Research, 126, 31–42.

By: J. Beard*, J. Hoppin*, M. Richards*, M. Alavanja*, A. Blair*, D. Sandler*, F. Kamel*

Contributors: J. Beard*, J. Hoppin*, M. Richards*, M. Alavanja*, A. Blair*, D. Sandler*, F. Kamel*

author keywords: Depression; Female; Incidence; Pesticides; Spouses
MeSH headings : Adult; Depression / chemically induced; Depression / epidemiology; Female; Humans; Iowa / epidemiology; Middle Aged; North Carolina / epidemiology; Pesticides / toxicity; Prospective Studies; Spouses / statistics & numerical data
TL;DR: This study adds further evidence that high level pesticide exposure, such as pesticide poisoning, is associated with increased risk of depression and sets a lower bound on the level of exposure related to depression, thereby providing reassurance that the moderate levels of pesticide exposure experienced by farmers' wives likely do not increase risk. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2013 journal article

Pesticides and respiratory health: where do we go from here?

Occupational and Environmental Medicine, 71(2), 80–80.

By: J. Hoppin n

Contributors: J. Hoppin n

MeSH headings : Air Pollutants, Occupational / toxicity; Female; Humans; Male; Occupational Exposure / adverse effects; Pesticides / toxicity; Pulmonary Disease, Chronic Obstructive / chemically induced
TL;DR: It is reported that occupational pesticide exposure is associated with poorer pulmonary function consistent with airway obstruction as measured by spirometry in two Dutch general population cohorts. (via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

Phthalate Exposure and Allergy in the U.S. Population: Results from NHANES 2005–2006

Environmental Health Perspectives, 121(10), 1129–1134.

MeSH headings : Adolescent; Adult; Child; Cross-Sectional Studies; Environmental Exposure / adverse effects; Environmental Exposure / analysis; Female; Humans; Hypersensitivity / etiology; Immune System / drug effects; Logistic Models; Male; Phthalic Acids / toxicity; Phthalic Acids / urine; United States; Young Adult
TL;DR: HMW phthalate metabolites, particularly MBzP, were positively associated with allergic symptoms and sensitization in adults, but there was no strong evidence for associations between phthalates and allergy in children 6–17 years of age. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2013 journal article

The concentration of bisphenol A in urine is affected by specimen collection, a preservative, and handling

Environmental Research, 126, 211–214.

By: M. Longnecker*, K. Harbak*, G. Kissling*, J. Hoppin*, M. Eggesbo*, T. Jusko*, J. Eide, H. Koch*

Contributors: M. Longnecker*, K. Harbak*, G. Kissling*, J. Hoppin*, M. Eggesbo*, T. Jusko*, J. Eide, H. Koch*

author keywords: Bisphenol A; Urine specimen collection; Contamination
MeSH headings : Adult; Benzhydryl Compounds / urine; Female; Humans; Phenols / urine; Pregnancy; Specimen Handling
TL;DR: Under the conditions used to collect urine specimens in the epidemiologic study, contamination with BPA occurred, and by two separate mechanisms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2013 journal article

Urinary Biomarkers for Phthalates Associated with Asthma in Norwegian Children

Environmental Health Perspectives, 121(2), 251–256.

By: R. Bertelsen*, K. Carlsen*, A. Calafat*, J. Hoppin*, G. Håland*, P. Mowinckel*, K. Carlsen*, M. Løvik*

Contributors: R. Bertelsen*, K. LØdrup Carlsen*, A. Calafat*, J. Hoppin*, G. Håland*, P. Mowinckel*, K. Carlsen*, M. LØvik*

author keywords: asthma; biomarkers; children; endocrine disruptors; phthalates
MeSH headings : Asthma / chemically induced; Biomarkers / urine; Body Burden; Child; Cross-Sectional Studies; Humans; Norway; Phthalic Acids / pharmacokinetics; Phthalic Acids / toxicity; Phthalic Acids / urine
TL;DR: Current asthma was associated with the highest quartiles of MCOP and MCNP, metabolites of two high molecular weight phthalates, diisononylphthalate and diisodecyl phthalate, respectively. (via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2012 journal article

Consumer product exposures associated with urinary phthalate levels in pregnant women

Journal of Exposure Science & Environmental Epidemiology, 22(5), 468–475.

By: J. Buckley*, R. Palmieri*, J. Matuszewski*, A. Herring*, D. Baird*, K. Hartmann*, J. Hoppin*

Contributors: J. Buckley*, R. Palmieri*, J. Matuszewski*, A. Herring*, D. Baird*, K. Hartmann*, J. Hoppin*

author keywords: phthalates; pregnancy; biomonitoring; urine; personal care products
MeSH headings : Adolescent; Adult; Cosmetics / adverse effects; Female; Household Articles; Household Products / adverse effects; Humans; Perfume / adverse effects; Phthalic Acids / metabolism; Phthalic Acids / urine; Pregnancy; Surveys and Questionnaires; Young Adult
TL;DR: Although personal care product use may be an important predictor of urinaryphthalate levels, most of the variability in phthalate exposure was not captured by the relatively comprehensive set of questionnaire items. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2012 journal article

Exposure to Tobacco Smoke in Utero and Subsequent Plasma Lipids, ApoB, and CRP among Adult Women in the MoBa Cohort

Environmental Health Perspectives, 120(11), 1532–1537.

By: L. Cupul-Uicab*, R. Skjaerven*, K. Haug*, G. Travlos*, R. Wilson*, M. Eggesbø*, J. Hoppin*, K. Whitworth*, M. Longnecker*

Contributors: L. Cupul-Uicab*, R. Skjaerven*, K. Haug*, G. Travlos*, R. Wilson*, M. Eggesbø*, J. Hoppin*, K. Whitworth*, M. Longnecker*

author keywords: clinical chemistry; C-reactive protein; metabolic syndrome; plasma lipids; prenatal exposure delayed effects; smoking; women
MeSH headings : Adolescent; Adult; Biomarkers / blood; C-Reactive Protein / metabolism; Cohort Studies; Female; Humans; Lipids / blood; Metabolic Syndrome / blood; Metabolic Syndrome / chemically induced; Metabolic Syndrome / epidemiology; Norway / epidemiology; Pregnancy; Prenatal Exposure Delayed Effects / blood; Prenatal Exposure Delayed Effects / chemically induced; Prenatal Exposure Delayed Effects / epidemiology; Risk Factors; Smoking / adverse effects; Smoking / epidemiology; Tobacco Smoke Pollution / adverse effects; Young Adult
TL;DR: In this population of pregnant women, in utero exposure to tobacco smoke was associated with high triglycerides and low HDL in adulthood, 18–44 years after exposure. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2012 journal article

Farming activities and carrying and lifting: The agricultural health study

Journal of Physical Activity and Health, 9(1), 39–47. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862940731&partnerID=MN8TOARS

By: E. Racine, S. Laditka, J. Dmochowski, M. Alavanja, D. Lee &