Works (277)
Updated: July 22nd, 2024 05:50
2024 personal communication
A call from 40 public health scientists for an end to the continuing humanitarian and environmental catastrophe in Gaza
London, L., Watterson, A., Mergler, D., Albin, M., Andrade-Rivas, F., Di Ciaula, A., … White, R. (2024, June 28).
author keywords: War; Gaza; Environmental impacts; Remediation
open access via doi.org (publisher)
Sources: Web Of Science, NC State University Libraries
Added: July 17, 2024
2024 article
Measurement of Hydro-EVE and 6:2 FTS in Blood from Wilmington, North Carolina, Residents, 2017-2018
Kotlarz, N., McCord, J., Wiecha, N., Weed, R. A., Cuffney, M., Enders, J. R., … Hoppin, J. A. (2024, February). ENVIRONMENTAL HEALTH PERSPECTIVES, Vol. 132.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: March 21, 2024
2024 journal article
Pesticide exposure, birth size, and gestational age in the ISA birth cohort, Costa Rica
ENVIRONMENTAL EPIDEMIOLOGY, 8(2).
TL;DR:
Prenatal exposure to chlorpyrifos and 2,4-D, and, possibly, mancozeb/ETU, and, possibly, mancozeb/ETU, may impair fetal growth.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 14, 2024
2024 article
Reanalysis of PFO5DoA Levels in Blood from Wilmington, North Carolina, Residents, 2017-2018
Kotlarz, N., McCord, J., Wiecha, N., Weed, R. A., Cuffney, M., Enders, J. R., … Hoppin, J. A. (2024, February). ENVIRONMENTAL HEALTH PERSPECTIVES, Vol. 132.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: March 21, 2024
2023 journal article
A cross-sectional analysis of medical conditions and environmental factors associated with fractional exhaled nitric oxide (FeNO) in women and children from the ISA birth cohort, Costa Rica
ENVIRONMENTAL RESEARCH, 233.
author keywords: Asthma FeNO pesticides environment rhinitis; wheeze
TL;DR:
Rinitis and wheeze were associated with elevated FeNO in this rural, agricultural population of women and children, and smoke from waste burning as well as para-occupational pesticide exposure may contribute to elevatedFeNO in rural communities.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 25, 2023
2023 article
Detection of the fungicide transformation product 4-hydroxychlorothalonil in serum of pregnant women from Sweden and Costa Rica
Krais, A. M. M., Joode, B. van W., Liljedahl, E. R., Blomberg, A. J., Ronnholm, A., Bengtsson, M., … Lindh, C. H. H. (2023, July 20). JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY, Vol. 7.
author keywords: Chlorothalonil; Fungicide; Exposure biomarker; Human biomonitoring; Aerial spraying; Pesticides
TL;DR:
For the first time, this study quantifies human exposure to the fungicide chlorothalonil and/or its transformation product 4-hydroxychlorothalonin and finds higher serum concentrations in women from a tropical agricultural setting as compared with women from the general population in Sweden.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 14, 2023
2023 journal article
Estimation of the Half-Lives of Recently Detected Per- and Polyfluorinated Alkyl Ethers in an Exposed Community
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 57(41), 15348–15355.
author keywords: exposure; PFAS; water; humans; environment; toxicokinetic modeling
TL;DR:
These fluoroethers had biological half-Lives longer than published half-lives for PFHxA and PFHpA but shorter than those for PFOA andPFOS (800-1200 days).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: October 7, 2023
2023 journal article
Factors associated with per- and polyfluoroalkyl substances (PFAS) serum concentrations in residents of New Hanover County, North Carolina: The GenX exposure study
ENVIRONMENTAL RESEARCH, 237.
author keywords: Per-and polyfluoroalkyl substances (PFAS); Fluoroethers; Contaminated drinking water; Environmental exposure predictors
TL;DR:
It is shown that drinking water is a primary source for serum PFAS concentrations among New Hanover County residents and years of residence in the lower Cape Fear Region as a surrogate for water consumption were important for both the association and predictive investigations.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: September 4, 2023
2023 journal article
PFAS levels in paired drinking water and serum samples collected from an exposed community in Central North Carolina
SCIENCE OF THE TOTAL ENVIRONMENT, 895.
author keywords: Per-andpolyfluoroalkyl substances; PFAS; Drinking water; Serum; Human health outcomes
TL;DR:
Extensive exposure to PFAS in Pittsboro is revealed and associations with clinical blood markers are revealed, suggesting potential health impacts in community residents.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: September 11, 2023
2022 article
Allergic and non-allergic wheeze among farm women in the Agricultural Health Study (2005-2010)
Islam, J. Y., Mohamed, A., Umbach, D. M., London, S. J., Henneberger, P. K., Freeman, L. E. B., … Hoppin, J. A. (2022, August 8). OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, Vol. 8.
author keywords: Allergy; Pesticides; Respiratory System
TL;DR:
Use of specific pesticides and certain farm activities may contribute to wheeze among farm women, as evaluated in the Agricultural Health Study.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: August 9, 2022
2022 journal article
Drinking Water-Associated PFAS and Fluoroethers and Lipid Outcomes in the GenX Exposure Study
ENVIRONMENTAL HEALTH PERSPECTIVES, 130(9).
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Alkanesulfonic Acids; Child; Cholesterol; Cross-Sectional Studies; Drinking Water; Environmental Pollutants; Fluorocarbons; Humans; Lipids; Middle Aged; Young Adult
TL;DR:
PFNA and PFOS were associated with higher levels of total and non-HDL cholesterol, with associations larger in magnitude among older adults, and fluoroethers appeared to be associated with HDL but not non- HDL lipid measures.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: September 8, 2022
2022 journal article
Pyrimethanil and chlorpyrifos air concentrations and pregnant women's urinary metabolites in the Infants' Environmental Health Study (ISA) Costa Rica ,
ENVIRONMENT INTERNATIONAL, 166.
author keywords: Urinary pesticide metabolites; Airborne pesticide exposure; Spatiotemporal model; Environmental exposure; Pesticides; Insecticides; Fungicides
TL;DR:
The results suggest inhalation of pyrimethanil and chlorpyrifos is a pathway of environmental exposure, and passive air samplers seems a useful technique to monitor environmental current-use pesticide exposures.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: July 11, 2022
2022 article
Respiratory and allergic outcomes among 5-year-old children exposed to pesticides
Islam, J. Y., Hoppin, J., Mora, A. M., Soto-Martinez, M. E., Cordoba Gamboa, L., Penaloza Castaneda, J. E., … Joode, B. (2022, February 24). THORAX, Vol. 2.
author keywords: asthma epidemiology; paediatric asthma; respiratory infection
MeSH headings : Infant; Pregnancy; Female; Humans; Child, Preschool; Pesticides / toxicity; Cough; Asthma; Rhinitis, Allergic; Respiratory Tract Infections; Pyrethrins; Exanthema
TL;DR:
Current pyrethroid exposure may affect children’s respiratory and allergic health at 5 years of age as pyrethroids are broadly used in home environments and agriculture and mancozeb in agriculture.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: March 28, 2022
2022 journal article
Source apportionment of serum PFASs in two highly exposed communities
SCIENCE OF THE TOTAL ENVIRONMENT, 855.
author keywords: Source apportionment; Receptor models; PFAS; Per fluoroalkyl substances
MeSH headings : Humans; Fluorocarbons / analysis; Nutrition Surveys; Drinking Water / analysis; Multivariate Analysis; Principal Component Analysis; Alkanesulfonic Acids / analysis; Water Pollutants, Chemical / analysis
TL;DR:
Effectiveness of three source apportionment methods for identifying contributors to human serum PFAS concentrations in two highly exposed populations in Colorado and North Carolina where drinking water was contaminated via upstream sources is assessed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: October 11, 2022
2022 journal article
Timing and Trends for Municipal Wastewater, Lab-Confirmed Case , and Syndromic Case Surveillance of COVID-19 in Raleigh, North Carolina
AMERICAN JOURNAL OF PUBLIC HEALTH, 113(1), 79–88.
Contributors: N. Kotlarz n , D. Holcomb n, T. Pasha n, S. Reckling n, J. Kays n, Y. Lai n, S. Daly n, S. Palani n
MeSH headings : Humans; COVID-19 / epidemiology; SARS-CoV-2; Wastewater; North Carolina / epidemiology; Sentinel Surveillance; RNA, Viral
TL;DR:
The results provide evidence for investment in SARS-CoV-2 wastewater and CLI surveillance to complement information provided through lab-confirmed cases, and in a major metropolitan area in 2020, the timing of and trends in municipal wastewater, lab- confirmed case, and syndromic case surveillance of COVID-19 were in general agreement.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: January 30, 2023
2021 article
Environmental exposures contribute to respiratory and allergic symptoms among women living in the banana growing regions of Costa Rica
Alhanti, B., Joode, B. van W., Martinez, M. S., Mora, A. M., Gamboa, L. C., Reich, B., … Hoppin, J. A. (2021, December 30). OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, Vol. 12.
author keywords: asthma; respiratory disease; allergy; pesticide; agriculture
MeSH headings : Asthma / epidemiology; Cohort Studies; Costa Rica / epidemiology; Eczema / epidemiology; Environmental Exposure / adverse effects; Exanthema / epidemiology; Female; Humans; Hypersensitivity / epidemiology; Musa; Pesticides / adverse effects; Respiratory Tract Diseases / epidemiology; Rhinitis / epidemiology; Smoke / adverse effects
TL;DR:
Findings suggest that environmental exposure to both pesticides and smoke may impact respiratory and skin-related allergic outcomes in women.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: December 31, 2021
2021 journal article
Exposure to common-use pesticides, manganese, lead, and thyroid function among pregnant women from the Infants' Environmental Health (ISA) study, Costa Rica
SCIENCE OF THE TOTAL ENVIRONMENT, 810.
author keywords: Thyroid function; Endocrine disruptors; Pesticides; Metals; Latin America
MeSH headings : Bayes Theorem; Costa Rica; Environmental Exposure / adverse effects; Female; Humans; Infant; Lead / adverse effects; Manganese / adverse effects; Pesticides / adverse effects; Pregnancy; Pregnant Women; Thyroid Gland / physiopathology; Thyrotropin; Thyroxine; Triiodothyronine
TL;DR:
Mancozeb (ETU) and pyrimethanil may inhibit FT4 secretion (hypothyroidism-like effect), while chlorpyrifos, pyrethroids, MnB, MnH, PbB and Mn showed hyperthyroidism -like effects.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: April 4, 2022
2021 journal article
Gestational Phthalate Exposure and Preschool Attention Deficit Hyperactivity Disorder in Norway
ENVIRONMENTAL EPIDEMIOLOGY, 5(4).
author keywords: phthalates; ADHD; Attention Deficit Hyperactivity Disorder; biomarkers; prenatal; gestational; MoBa; The Norwegian Mother; Father and Child Cohort Study
TL;DR:
Results suggest gestational phthalate exposure may impact the behavior of children as young as 3 years, and boys, but not girls, mono-n-butyl phthalates exposure was associated with increased odds of ADHD.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: May 16, 2022
2020 journal article
Associations between urine phthalate metabolites and thyroid function in pregnant women and the influence of iodine status
ENVIRONMENT INTERNATIONAL, 137.
author keywords: Phthalates; Thyroid hormones; Pregnancy; Iodine; The Norwegian Mother; Father and Child Cohort study; MoBa
MeSH headings : Child; Cohort Studies; Cross-Sectional Studies; Environmental Exposure; Environmental Pollutants; Female; Humans; Iodine; Norway; Phthalic Acids / toxicity; Phthalic Acids / urine; Pregnancy; Prospective Studies; Thyroid Gland / drug effects; Thyroid Gland / physiopathology
TL;DR:
It is found that phthalate exposure is associated with thyroid function in mid-pregnancy among Norwegian women, and that iodine intake, which is essential for thyroid health, could influence some of these relationships.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: April 20, 2020
2020 journal article
Gender differences in respiratory health outcomes among farming cohorts around the globe: findings from the AGRICOH consortium
JOURNAL OF AGROMEDICINE, 26(2), 97–108.
author keywords: Farmers; Respiratory Health; Gender; Farmworkers; Occupational Exposure
MeSH headings : Adult; Agricultural Workers' Diseases / epidemiology; Agriculture; Female; Humans; Male; Occupational Exposure; Outcome Assessment, Health Care; Prevalence; Prospective Studies; Risk Factors; Sex Factors
TL;DR:
Assessment of respiratory disease prevalence among adults in 18 cohorts representing over 200,000 farmers, farm workers, and their spouses from six continents indicates that respiratory outcomes are common among farmers around the world despite differences in agricultural production.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: April 6, 2020
2020 journal article
Measurement of Novel, Drinking Water-Associated PFAS in Blood from Adults and Children in Wilmington, North Carolina
ENVIRONMENTAL HEALTH PERSPECTIVES, 128(7).
MeSH headings : Adult; Alkanesulfonic Acids; Caprylates; Child; Drinking Water; Environmental Exposure / statistics & numerical data; Female; Fluorocarbons / analysis; Fluorocarbons / blood; Humans; Male; North Carolina; Nutrition Surveys; Rivers; Water Pollutants, Chemical / analysis
TL;DR:
Poorly understood fluoroethers released into the Cape Fear River by a fluorochemical manufacturing facility were detected in blood samples from Wilmington, North Carolina, residents.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 24, 2020
2020 journal article
Prenatal pesticide exposure and respiratory health outcomes in the first year of life: Results from the infants' Environmental Health (ISA) study
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH, 225.
author keywords: Pesticides; Mancozeb; Respiratory outcomes; Infants; Costa Rica
MeSH headings : Adult; Environmental Pollutants / urine; Ethylenethiourea / metabolism; Female; Humans; Infant; Infant Health; Male; Maneb / urine; Maternal Exposure; Maternal-Fetal Exchange; Pesticides / urine; Pregnancy; Prenatal Exposure Delayed Effects; Respiratory Sounds; Respiratory Tract Infections / epidemiology; Young Adult; Zineb / urine
TL;DR:
Exposure to mancozeb/ETU during the first half of pregnancy may be associated with respiratory outcomes in the first year of life, and null associations between other pesticide metabolites measured during pregnancy and respiratory outcomes are observed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: April 14, 2020
2019 journal article
Animal production, insecticide use and self-reported symptoms and diagnoses of COPD, including chronic bronchitis, in the Agricultural Health Study
ENVIRONMENT INTERNATIONAL, 127, 764–772.
author keywords: Epidemiology; Occupational health; Environmental health; Pesticide
MeSH headings : Adult; Animal Husbandry; Animals; Bronchitis, Chronic / epidemiology; Farmers; Female; Humans; Insecticides / toxicity; Logistic Models; Male; Middle Aged; Occupational Exposure; Odds Ratio; Prevalence; Pulmonary Disease, Chronic Obstructive / chemically induced; Pulmonary Disease, Chronic Obstructive / epidemiology; Risk Factors; United States / epidemiology
TL;DR:
Animal production work, including insecticide use, was positively associated with chronic bronchitis symptoms; but not consistently with COPD diagnosis alone; the results support the need for further investigation into the role of animal production-related exposures in the etiology of COPD and better respiratory protection for agricultural workers.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: June 17, 2019
2019 journal article
Associations between access to healthcare, environmental quality, and end-stage renal disease survival time: Proportional-hazards models of over 1,000,000 people over 14 years
PLOS ONE, 14(3).
Contributors: M. Kosnik n, D. Reif n , D. Lobdell *, T. Astell-Burt *, X. Feng *, J. Hader*, n
Ed(s): W. Cheungpasitporn
MeSH headings : Adolescent; Adult; Aged; Air Pollution / adverse effects; Female; Health Services Accessibility; Humans; Kidney Failure, Chronic / epidemiology; Male; Middle Aged; Prevalence; Proportional Hazards Models; Risk Factors; Socioeconomic Factors; United States / epidemiology; Water Quality; Young Adult
TL;DR:
The results demonstrate the importance of considering multiple factors when studying ESRD survival and future efforts should consider additional components of the broader environment.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 9, 2019
2018 journal article
An algorithm for quantitatively estimating non-occupational pesticide exposure intensity for spouses in the Agricultural Health Study
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY, 29(3), 344–357.
MeSH headings : Adult; Agriculture; Algorithms; Environmental Exposure / analysis; Farmers; Female; Humans; Male; Pesticides / analysis; Spouses; Surveys and Questionnaires
TL;DR:
A quantitative, active ingredient-specific algorithm for cumulative (adult, married lifetime) non-occupational pesticide exposure intensity for spouses of farmers who applied pesticides in the Agricultural Health Study (AHS) is developed and will facilitate improved etiologic analyses in the AHS spouses.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 6, 2019
2018 journal article
Endotoxin enhances respiratory effects of phthalates in adults: Results from NHANES 2005-6
ENVIRONMENTAL RESEARCH, 162, 280–286.
author keywords: Allergy; Asthma; Wheeze; Dust endotoxin; Phthalates
MeSH headings : Adult; Asthma / chemically induced; Cross-Sectional Studies; Dust; Endotoxins / toxicity; Environmental Exposure; Humans; Nutrition Surveys; Phthalic Acids / toxicity; Respiratory Sounds / drug effects
TL;DR:
The lack of an association between wheeze or asthma and phthalate when endotoxin exposure was low suggests that phthalates alone may not increase these symptoms, whereas this cross‐sectional study cannot address key temporal issues.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2018 journal article
Prenatal Phthalates, Maternal Thyroid Function, and Risk of Attention-Deficit Hyperactivity Disorder in the Norwegian Mother and Child Cohort
ENVIRONMENTAL HEALTH PERSPECTIVES, 126(5).
MeSH headings : Adult; Attention Deficit Disorder with Hyperactivity / epidemiology; Attention Deficit Disorder with Hyperactivity / urine; Case-Control Studies; Cohort Studies; Female; Humans; Male; Mothers; Phthalic Acids / urine; Pregnancy; Prenatal Exposure Delayed Effects; Surveys and Questionnaires; Thyroid Gland / physiology
TL;DR:
In this population-based case–control study of clinical ADHD, maternal urinary concentrations of DEHP were monotonically associated with increased risk of ADHD.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2018 journal article
SPARSE BAYESIAN ADDITIVE NONPARAMETRIC REGRESSION WITH APPLICATION TO HEALTH EFFECTS OF PESTICIDES MIXTURES
STATISTICA SINICA, 30(1), 55–79.
author keywords: Additive nonparametric regression; Bayesian variable selection; continuous shrinkage prior; environmental epidemiology; posterior consistency
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: October 26, 2020
2017 journal article
Assessing the Exposome with External Measures: Commentary on the State of the Science and Research Recommendations
Annual Review of Public Health, 38(1), 215–239.
author keywords: exposome; external exposures; geographic information systems; remote sensing; global positioning systems; smartphones
MeSH headings : Environmental Exposure / adverse effects; Epigenomics; Geographic Information Systems; Health Behavior; Humans; Life Style; Research
TL;DR:
Major scientific and technological advances that inform external assessment of the exposome are described, including geographic information systems; remote sensing; global positioning system and geolocation technologies; portable and personal sensing; and self-reported questionnaire assessments, which increasingly rely on Internet-based platforms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2017 journal article
Assessing the Potential for Bias From Nonresponse to a Study Follow-up Interview: An Example From the Agricultural Health Study
American Journal of Epidemiology, 186(4), 395–404.
author keywords: attrition; epidemiologic methods; inverse probability weights; loss to follow-up; occupational/environmental epidemiology; prospective studies; selection bias
MeSH headings : Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / etiology; Agricultural Workers' Diseases / prevention & control; Bias; Cause of Death; Epidemiologic Research Design; Farmers / statistics & numerical data; Female; Follow-Up Studies; Humans; Interviews as Topic; Iowa / epidemiology; Lost to Follow-Up; Male; Middle Aged; Neoplasms / epidemiology; North Carolina; Odds Ratio; Prospective Studies; Smoking / epidemiology
TL;DR:
This example provides a demonstration of investigating the influence of attrition in cohort studies using information that has been self-reported after enrollment, and the ability of inverse probability weighting (IPW) to reduce bias.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2017 journal article
House Dust Endotoxin Levels Are Associated with Adult Asthma in a U.S. Farming Population
Annals of the American Thoracic Society, 14(3), 324–331.
author keywords: pulmonary function; atopy; wheeze; CD14; TLR4
MeSH headings : Aged; Agriculture / statistics & numerical data; Asthma / epidemiology; Asthma / genetics; Case-Control Studies; Dust / analysis; Endotoxins / analysis; Environmental Exposure / adverse effects; Female; Gene-Environment Interaction; Humans; Lipopolysaccharide Receptors / genetics; Logistic Models; Male; Middle Aged; Odds Ratio; Respiratory Sounds; Surveys and Questionnaires; Toll-Like Receptor 4 / genetics; United States / epidemiology
TL;DR:
House dust endotoxin was associated with current atopic and nonatopic asthma in a U.S. farming population and was associatedwith lower pulmonary function in patients with asthma, and the degree of the association with asthma depended on early‐life farm exposures.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2017 journal article
House Dust Endotoxin and Periphera lLeukocyte Counts: Results from Two Large Epidemiologic Studies
ENVIRONMENTAL HEALTH PERSPECTIVES, 125(5).
MeSH headings : Asthma / epidemiology; Dust / analysis; Endotoxins / adverse effects; Endotoxins / analysis; Female; Humans; Leukocyte Count; Linear Models; Male; Nutrition Surveys; Pulmonary Disease, Chronic Obstructive / epidemiology; Toll-Like Receptor 4 / genetics
TL;DR:
There is a statistically significant, positive association between endotoxin concentration and total leukocyte number in the National Health and Nutrition Examination Survey 2005–2006 and the Agricultural Lung Health Study (ALHS), the first report of an association between house dust endotoxin and leukocytes count in a national survey.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2017 journal article
Insecticide Use and Breast Cancer Riskamong Farmers' Wives in the Agricultural Health Study
ENVIRONMENTAL HEALTH PERSPECTIVES, 125(9).
MeSH headings : Adult; Aged; Agriculture; Agrochemicals / metabolism; Agrochemicals / toxicity; Breast Neoplasms / epidemiology; Farmers; Female; Humans; Incidence; Insecticides / metabolism; Insecticides / toxicity; Middle Aged; Occupational Exposure / statistics & numerical data; Organophosphates / metabolism; Organophosphates / toxicity
TL;DR:
Use of several organophosphate insecticides was associated with elevated breast cancer risk among wives of pesticide applicators (farmers), but associations for the women’s and husbands’ use of these insecticides showed limited concordance.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2017 journal article
Organic solvent exposure and depressive symptoms among licensed pesticide applicators in the Agricultural Health Study
International Archives of Occupational and Environmental Health, 90(8), 849–857.
author keywords: Farmers; Organic solvent exposure; Depressive symptoms; CES-D; Epidemiology
MeSH headings : Aged; Agriculture; Depression / epidemiology; Humans; Iowa; Male; Middle Aged; North Carolina; Occupational Exposure / adverse effects; Organic Chemicals / adverse effects; Pesticides; Risk Factors; Solvents / adverse effects; Surveys and Questionnaires
TL;DR:
Efforts to limit exposure to organic solvents may reduce the risk of depressive symptoms among farmers after associations between questionnaire-based metrics of organic solvent exposure and depressive symptoms were examined.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 17, 2019
2017 journal article
Raw milk consumption and other early-life farm exposures and adult pulmonary function in the Agricultural Lung Health Study
Thorax, 73(3), 279–282.
Contributors: A. Wyss *, J. House n , n , M. Richards*, J. Hankinson, S. Long*, P. Henneberger *, L. Beane Freeman *
author keywords: COPD epidemiology; Asthma Epidemiology; Allergic lung disease; Occupational Lung Disease; Respiratory Measurement
MeSH headings : Adult; Aged; Agriculture; Animals; Case-Control Studies; Child; Child, Preschool; Environmental Exposure; Farms / statistics & numerical data; Female; Humans; Lung / physiopathology; Male; Middle Aged; Milk / physiology; Prospective Studies; Respiratory Physiological Phenomena; Spirometry / methods; United States
TL;DR:
A novel association between raw milk consumption and higher pulmonary function that lasts into older adulthood is reported and did not find appreciable associations with other early-life farming exposures.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018
2017 journal article
Sleep apnea and pesticide exposure in a study of US farmers
SLEEP HEALTH, 4(1), 20–26.
author keywords: Pesticides; Sleep apnea; Carbofuran; Carbamates; Sleep disorder breathing; Agriculture
MeSH headings : Carbofuran / adverse effects; Case-Control Studies; Farmers / statistics & numerical data; Humans; Male; Occupational Exposure / adverse effects; Pesticides / toxicity; Prospective Studies; Sleep Apnea Syndromes / chemically induced; Surveys and Questionnaires; United States / epidemiology
TL;DR:
The results in a male agricultural population suggests that exposure to carbofuran is positively associated with sleep apnea, a pesticide canceled in the United States in 2009 for most agricultural purposes but persists in the environment and remains in use in some other countries.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
Advancing Exposure Science through Chemical Data Curation and Integration in the Comparative Toxicogenomics Database
Environmental Health Perspectives, 124(10), 1592–1599.
Contributors: C. Grondin n, A. Davis n, T. Wiegers n, B. King *, J. Wiegers n, D. Reif n , n , C. Mattingly n
TL;DR:
Curation and integration of exposure data within the CTD provides researchers with new opportunities to correlate exposures with human health outcomes, to identify underlying potential molecular mechanisms, and to improve understanding about the exposome.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018
2016 journal article
Early-life farm exposures and adult asthma and atopy in the Agricultural Lung Health Study
Journal of Allergy and Clinical Immunology, 140(1), 249–256.e14.
Contributors: J. House* , A. Wyss *, n , M. Richards*, S. Long*, D. Umbach *, P. Henneberger *, L. Beane Freeman
author keywords: Agriculture; agricultural workers' diseases; allergy and immunology; asthma; hygiene hypothesis; IgE; prenatal exposure delayed effects
MeSH headings : Aged; Asthma / epidemiology; Case-Control Studies; Environmental Exposure; Farms; Female; Humans; Hypersensitivity, Immediate / blood; Hypersensitivity, Immediate / epidemiology; Immunoglobulin E / blood; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Odds Ratio; Pulmonary Disease, Chronic Obstructive / epidemiology; Smoking / epidemiology
TL;DR:
In a large US farming population, early‐life farm exposures, particularly maternal farming activities while pregnant, were strongly associated with reduced risk of atopy in adults, suggesting that protective associations of early‐ life farming exposures on atopy endure across the life course.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018
2016 journal article
Greater Coronary Heart Disease Risk With Lower Intensity and Longer Duration Smoking Compared With Higher Intensity and Shorter Duration Smoking: Congruent Results Across Diverse Cohorts
Nicotine & Tobacco Research, 19(7), ntw290.
MeSH headings : Aged; Cohort Studies; Coronary Disease / epidemiology; Coronary Disease / mortality; Double-Blind Method; Finland / epidemiology; Humans; Male; Middle Aged; Risk Factors; Smoking / epidemiology; Smoking Cessation / methods; Time Factors; Tobacco Products / statistics & numerical data
TL;DR:
In inverse smoking intensity effects in multiple cohorts with differing smoking patterns and other characteristics are observed, suggesting a common underlying phenomenon that offers clues to better understanding biological mechanisms and reinforces the importance of cessation rather than smoking less to reduce CHD risk.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2016 journal article
High pesticide exposure events and DNA methylation among pesticide applicators in the agricultural health study
Environmental and Molecular Mutagenesis, 58(1), 19–29.
author keywords: DNA methylation; pesticides; exposure; Agricultural Health Study; epigenetics
MeSH headings : Air Pollutants, Occupational / toxicity; Antigens, CD; Cadherins / genetics; DNA / blood; DNA Methylation / drug effects; DNA Methylation / genetics; DNA Modification Methylases / genetics; DNA Repair Enzymes / genetics; Farmers; Glutathione S-Transferase pi / genetics; Humans; Iowa; Male; North Carolina; Occupational Exposure / adverse effects; Occupational Exposure / analysis; Occupational Health; Pesticides / toxicity; Promoter Regions, Genetic; Prospective Studies; Surveys and Questionnaires; Tumor Suppressor Proteins / genetics
TL;DR:
Evaluated association between experiencing unusually high pesticide exposure events (HPEEs) and DNAm among pesticide applicators in the Agricultural Health Study, a prospective study of applicators from Iowa and North Carolina found non‐specific HPEEs may contribute to increasedDNAm in GSTp1, and in some groups, reduced DNAm in MGMT and LINE‐1.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2016 journal article
Occupational Exposure to Pesticides and the Incidence of Lung Cancer in the Agricultural Health Study
Environmental Health Perspectives, 125(4), 544–551.
MeSH headings : Agricultural Workers' Diseases / epidemiology; Agriculture; Humans; Incidence; Iowa / epidemiology; Lung Neoplasms / epidemiology; North Carolina / epidemiology; Occupational Exposure / statistics & numerical data; Pesticides; Proportional Hazards Models; Prospective Studies
TL;DR:
An association between chlorimuron ethyl, a herbicide introduced in 1986, and lung cancer that has not been previously reported is found.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2016 journal article
Organic Food in the Diet: Exposure and Health Implications
Annual Review of Public Health, 38(1), 295–313.
author keywords: organic food; organic vegetables; naturalness; compositional differences; health effects
MeSH headings : Agriculture / methods; Diet; Food; Food Contamination / prevention & control; Food, Organic; Humans; Nutritive Value
TL;DR:
This review provides an update on market data and consumer preferences for organic food and summarizes the scientific evidence for compositional differences and health benefits of organic compared with conventionally produced food.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2016 journal article
Pesticide exposure and neurodevelopment in children aged 6–9 years from Talamanca, Costa Rica
Cortex, 85, 137–150.
author keywords: Pesticides; Children; Environmental exposure; Neurobehavioral effects; Biomarkers
MeSH headings : Benzoates / urine; Central Nervous System / drug effects; Central Nervous System / growth & development; Child; Child Behavior; Chlorpyrifos / urine; Costa Rica; Cross-Sectional Studies; Female; Humans; Male; Maneb / urine; Pesticides / urine; Pyridones / urine; Zineb / urine
TL;DR:
The findings indicate that children living near banana and plantain plantations are exposed to pesticides that may affect their neurodevelopment, which for certain domains may differ between boys and girls.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2016 journal article
Pesticides are Associated with Allergic and Non-Allergic Wheeze among Male Farmers
Environmental Health Perspectives, 125(4), 535–543.
MeSH headings : Adult; Agricultural Workers' Diseases / epidemiology; Agriculture; Farmers; Humans; Iowa / epidemiology; Male; North Carolina / epidemiology; Occupational Exposure / statistics & numerical data; Pesticides; Prospective Studies; Respiratory Sounds
TL;DR:
Evidence is seen of an exposure–response relationship for several pesticides including the commonly used herbicides 2,4-D and glyphosate, the insecticides permethrin and carbaryl, and the rodenticide warfarin, which are commonly used in agricultural and residential settings with adverse respiratory effects.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: NC State University Libraries, NC State University Libraries, Crossref
Added: August 6, 2018
2016 journal article
Relative Contributions of Agricultural Drift, Para-Occupational, and Residential Use Exposure Pathways to House Dust Pesticide Concentrations: Meta-Regression of Published Data
Environmental Health Perspectives, 125(3), 296–305.
MeSH headings : Agriculture; Air Pollutants / analysis; Air Pollution, Indoor / statistics & numerical data; Dust / analysis; Environmental Exposure / statistics & numerical data; Environmental Monitoring; Housing / statistics & numerical data; Humans; Occupational Exposure; Pesticides / analysis
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2016 journal article
Response to “Comment on ‘Rheumatoid Arthritis in Agricultural Health Study Spouses: Associations with Pesticides and Other Farm Exposures’”
Response to “Comment on ‘Rheumatoid Arthritis in Agricultural Health Study Spouses: Associations with Pesticides and Other Farm Exposures.’” Environmental Health Perspectives, 124(11), A197–A197.
MeSH headings : Agricultural Workers' Diseases; Agriculture; Arthritis, Rheumatoid; Farms; Humans; Occupational Exposure; Pesticides; Spouses
TL;DR:
It is important to note, however, that it is unlikely that metals exposure accounts for the other observed pesticide associations in the authors' study, including those with glyphosate and DDT.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2016 journal article
Rheumatoid Arthritis in Agricultural Health Study Spouses: Associations with Pesticides and Other Farm Exposures
Environmental Health Perspectives, 124(11), 1728–1734.
MeSH headings : Arthritis, Rheumatoid / epidemiology; Cohort Studies; Environmental Exposure; Environmental Pollutants / toxicity; Farmers; Female; Fertilizers / toxicity; Humans; Pesticides / toxicity; Solvents / toxicity; Spouses
TL;DR:
It is suggested that specific agricultural pesticides, solvents, and chemical fertilizers may increase the risk of RA in women, while exposures involving animal contact may be protective.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2016 journal article
Urinary concentrations of phthalate metabolites and bisphenol A and associations with follicular-phase length, luteal-phase length, fecundability, and early pregnancy loss
Environmental Health Perspectives, 124(3), 321–328.
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
A Review of Nonoccupational Pathways for Pesticide Exposure in Women Living in Agricultural Areas
Environmental Health Perspectives, 123(6), 515–524.
MeSH headings : Agriculture; Environmental Exposure; Environmental Pollutants / metabolism; Female; Humans; North America; Pesticides / metabolism
TL;DR:
An improved understanding of nonoccupational pesticide exposure pathways in women living in agricultural areas is critical for studying health effects in women and for designing effective exposure-reduction strategies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2015 journal article
Associations of Ozone and PM2.5 Concentrations With Parkinsonʼs Disease Among Participants in the Agricultural Health Study
Journal of Occupational and Environmental Medicine, 57(5), 509–517.
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agriculture; Air Pollutants, Occupational / adverse effects; Air Pollutants, Occupational / analysis; Air Pollution / adverse effects; Air Pollution / analysis; Child; Farmers; Female; Follow-Up Studies; Humans; Iowa; Logistic Models; Male; Middle Aged; North Carolina; Occupational Diseases / etiology; Occupational Exposure / adverse effects; Occupational Exposure / analysis; Ozone / adverse effects; Ozone / analysis; Parkinson Disease / etiology; Particulate Matter / adverse effects; Particulate Matter / analysis; Young Adult
TL;DR:
The plausibility of an effect of ambient concentrations of these pollutants on Parkinson's disease risk is supported by experimental data demonstrating damage to dopaminergic neurons at relevant concentrations.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020
2015 journal article
Cancer incidence and metolachlor use in the Agricultural Health Study: An update
International Journal of Cancer, 137(11), 2630–2643.
author keywords: cancer; epidemiology; pesticide; occupation
MeSH headings : Acetamides / toxicity; Aged; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Carcinogens / toxicity; Cohort Studies; Female; Herbicides / toxicity; Humans; Incidence; Iowa / epidemiology; Male; Middle Aged; Neoplasms / epidemiology; North Carolina / epidemiology; Occupational Exposure / adverse effects; Prospective Studies
TL;DR:
A suggestion of an association between metolachlor and liver cancer among pesticide applicators is a novel finding and echoes observation of increased liver neoplasms in some animal studies, however, the findings for both liver cancer and follicular cell lymphoma warrant follow‐up to better differentiate effects of metolchlor use from other factors.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2015 journal article
Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma
Nature Communications, 6(1).
MeSH headings : Asthma / genetics; Carrier Proteins / genetics; Female; Genetic Predisposition to Disease / genetics; Genome-Wide Association Study / methods; Humans; Linkage Disequilibrium / genetics; Male; Membrane Proteins / genetics; Neoplasm Proteins / genetics
TL;DR:
The results suggest that associations with rare and low-frequency variants are ethnic specific and not likely to explain a significant proportion of the ‘missing heritability’ of asthma.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: January 5, 2020
2015 journal article
Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma
Nature Communications, 6.
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
Farm Characteristics, Allergy Symptoms, and Risk of Non-Hodgkin Lymphoid Neoplasms in the Agricultural Health Study
Cancer Epidemiology Biomarkers & Prevention, 24(3), 587–594.
MeSH headings : Adult; Aged; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / etiology; Agricultural Workers' Diseases / immunology; Cohort Studies; Farmers / statistics & numerical data; Female; Humans; Hypersensitivity / epidemiology; Hypersensitivity / etiology; Hypersensitivity / immunology; Lymphoma, Non-Hodgkin / epidemiology; Lymphoma, Non-Hodgkin / etiology; Lymphoma, Non-Hodgkin / immunology; Male; Middle Aged; North Carolina / epidemiology; Prospective Studies; Risk Factors
TL;DR:
Both the reduced risk of NHL among those with allergy symptoms and specific farm exposures in adulthood, and the increased risk among those who grew up on a farm suggest that the host immune response to agricultural allergens may influence NHL development.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2015 journal article
IARC Monographs: 40 Years of Evaluating Carcinogenic Hazards to Humans
Environmental Health Perspectives, 123(6), 507–514.
MeSH headings : Biomedical Research; Carcinogens, Environmental; Humans; International Agencies / organization & administration; Neoplasms; Public Health; Publications
TL;DR:
Criticism of the IARC classification process are unconvincing, the procedures employed by IARC to assemble Working Groups of scientists from the various disciplines and the techniques followed to review the literature and perform hazard assessment of various agents provide a balanced evaluation and an appropriate indication of the weight of the evidence.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: January 5, 2020
2015 journal article
IARC monographs: 40 years of evaluating carcinogenic hazards to humans
Environmental Health Perspectives, 123(6), 507–514.
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
Incidence of solid tumours among pesticide applicators exposed to the organophosphate insecticide diazinon in the Agricultural Health Study: an updated analysis
Occupational and Environmental Medicine, 72(7), 496–503.
MeSH headings : Adult; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / etiology; Agriculture; Diazinon / adverse effects; Humans; Incidence; Iowa / epidemiology; Kidney Neoplasms / epidemiology; Kidney Neoplasms / etiology; Lung Neoplasms / epidemiology; Lung Neoplasms / etiology; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Organophosphorus Compounds / adverse effects; Pesticides / adverse effects; Prospective Studies; Prostatic Neoplasms / epidemiology; Prostatic Neoplasms / etiology
TL;DR:
The authors' updated evaluation of diazinon provides additional evidence of an association with lung cancer risk and newly identified links to kidney cancer and associations with aggressive prostate cancer require further evaluation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2015 journal article
Investing in prospective cohorts for etiologic study of occupational exposures
American Journal of Industrial Medicine, 58(2), 113–122.
author keywords: prospective cohorts; agricultural exposures; occupational epidemiology
MeSH headings : Agricultural Workers' Diseases / etiology; Epidemiologic Research Design; Humans; Occupational Exposure / analysis; Occupational Medicine; Prospective Studies
TL;DR:
Experience using this design to study agricultural workers to identify conditions that might foster use of prospective cohorts to study other occupational settings to investigate high priority, occupational exposures.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2015 journal article
Opinions of clinical veterinarians at a US veterinary teaching hospital regarding antimicrobial use and antimicrobial-resistant infections
Journal of the American Veterinary Medical Association, 247(8), 938–944.
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Bacteria / drug effects; Bacterial Infections / microbiology; Bacterial Infections / veterinary; Cross-Sectional Studies; Data Collection; Drug Resistance, Bacterial; Education, Veterinary; Female; Hospitals, Animal; Humans; Male; Professional Practice; Schools, Veterinary; United States; Veterinarians
TL;DR:
Findings indicated that veterinarians at this teaching hospital were concerned about antimicrobial resistance, thought antimicrobials were overprescribed, and supported restricting use of certain antimicrobial classes in companion animals.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2015 journal article
Organic Food Consumption during Pregnancy and Hypospadias and Cryptorchidism at Birth: The Norwegian Mother and Child Cohort Study (MoBa)
Environmental Health Perspectives, 124(3), 357–364.
MeSH headings : Adolescent; Adult; Cohort Studies; Cryptorchidism / epidemiology; Diet; Female; Food, Organic; Humans; Hypospadias / epidemiology; Infant, Newborn; Male; Maternal Exposure / adverse effects; Norway / epidemiology; Pregnancy; Prospective Studies; Risk Factors
TL;DR:
Consumption of organically produced foods during pregnancy was associated with a lower prevalence of hypospadias in the Norwegian Mother and Child Cohort Study population, and replication in other study populations is required.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2015 journal article
Organophosphate insecticide use and cancer incidence among spouses of pesticide applicators in the Agricultural Health Study
Occupational and Environmental Medicine, 72(10), 736–744.
MeSH headings : Adult; Age Distribution; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Cohort Studies; Diazinon / adverse effects; Female; Humans; Incidence; Insecticides / adverse effects; Iowa / epidemiology; Male; Middle Aged; Neoplasms / chemically induced; Neoplasms / epidemiology; North Carolina / epidemiology; Occupational Exposure / adverse effects; Occupational Exposure / statistics & numerical data; Organophosphates / adverse effects; Retrospective Studies; Risk Assessment; Spouses / statistics & numerical data; Survival Rate; Young Adult
TL;DR:
This study represents the first comprehensive analysis of OP use and cancer risk among women, suggesting potential for hormonally-mediated effects.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2015 journal article
Pesticide Use and Relative Leukocyte Telomere Length in the Agricultural Health Study
PLOS ONE, 10(7), e0133382.
Ed(s): T. Nawrot
MeSH headings : Acetamides / poisoning; Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / diagnosis; Agricultural Workers' Diseases / genetics; Health Occupations / statistics & numerical data; Humans; Iowa; Leukocytes / drug effects; Leukocytes / metabolism; Malathion; Male; Middle Aged; North Carolina; Occupational Exposure / analysis; Organophosphate Poisoning / diagnosis; Organophosphate Poisoning / genetics; Pesticides / poisoning; Prospective Studies; Surveys and Questionnaires; Telomere / drug effects; Telomere / genetics; Telomere Homeostasis / drug effects; Telomere Shortening / drug effects
TL;DR:
Ass associations between occupational pesticide use reported at three time points and relative telomere length (RTL) in the Agricultural Health Study are examined, suggesting that leukocyte TL may be impacted by cumulative use and recent use of certain pesticides.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2015 journal article
Pesticide exposure and end-stage renal disease risk among wives of pesticide applicators in the Agricultural Health Study
Environmental Research, 143, 198–210.
author keywords: Pesticide exposure; End-stage renal disease; Farm women; Agricultural exposures
MeSH headings : Adolescent; Adult; Aged; Environmental Exposure / adverse effects; Environmental Exposure / analysis; Farmers / statistics & numerical data; Female; Humans; Incidence; Iowa / epidemiology; Kidney Failure, Chronic / chemically induced; Kidney Failure, Chronic / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Pesticides / analysis; Pesticides / toxicity; Proportional Hazards Models; Prospective Studies; Risk Factors; Spouses / statistics & numerical data; Surveys and Questionnaires; Time Factors; Young Adult
TL;DR:
ESRD may be associated with direct and/or indirect exposure to pesticides among farm women and future studies should evaluate indirect exposure risk among other rural populations.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2015 journal article
Pesticide use and risk of end-stage renal disease among licensed pesticide applicators in the Agricultural Health Study
Occupational and Environmental Medicine, 73(1), 3–12.
MeSH headings : Agriculture; Herbicides / adverse effects; Humans; Incidence; Iowa; Kidney Failure, Chronic / etiology; Male; North Carolina; Occupational Diseases / etiology; Occupational Exposure / adverse effects; Occupations; Pesticides / adverse effects; Proportional Hazards Models; Prospective Studies; Risk Factors
TL;DR:
The findings support an association between ESRD and chronic exposure to specific pesticides, and suggest pesticide exposures resulting in medical visits may increase the risk of E SRD.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2015 journal article
Urinary Concentrations of Phthalate Metabolites and Bisphenol A and Associations with Follicular-Phase Length, Luteal-Phase Length, Fecundability, and Early Pregnancy Loss
Environmental Health Perspectives, 124(3), 321–328.
MeSH headings : Abortion, Spontaneous / chemically induced; Abortion, Spontaneous / urine; Adult; Benzhydryl Compounds / toxicity; Benzhydryl Compounds / urine; Environmental Pollutants / toxicity; Environmental Pollutants / urine; Female; Fertility / drug effects; Follicular Phase / drug effects; Humans; Luteal Phase / drug effects; Phenols / toxicity; Phenols / urine; Phthalic Acids / toxicity; Phthalic Acids / urine; Pregnancy; Pregnancy Trimester, First
TL;DR:
Menstrual cycle–specific estimates of urinary BPA and phthalate metabolites were not associated with detrimental alterations in follicular-phase length, time to pregnancy, or early pregnancy loss, and in fact, DEHP [di(2-ethylhexyl)phthalate] metabolites and ΣDEHP were associated with reduced early loss.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 17, 2019
2015 journal article
Use of Dieselized Farm Equipment and Incident Lung Cancer: Findings from the Agricultural Health Study Cohort
Environmental Health Perspectives, 124(5), 611–618.
MeSH headings : Agricultural Workers' Diseases / epidemiology; Agriculture / statistics & numerical data; Farmers; Iowa / epidemiology; Lung Neoplasms / epidemiology; North Carolina / epidemiology; Occupational Exposure / statistics & numerical data; Vehicle Emissions
TL;DR:
Preliminary evidence of an increased risk of lung adenocarcinoma among daily drivers of diesel tractors is provided and it is suggested that exposure to endotoxins may modify the impact of diesel exposure on lung cancer risk.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Accuracy of residential geocoding in the Agricultural Health Study
International Journal of Health Geographics, 13(1), 37.
author keywords: Geocoding; Positional error; Rural location; Environmental exposure assessment; Accuracy
MeSH headings : Agriculture / statistics & numerical data; Cohort Studies; Environmental Exposure / analysis; Environmental Exposure / statistics & numerical data; Female; Geographic Mapping; Health Status; Humans; Iowa / epidemiology; Male; North Carolina / epidemiology; Pesticides; Prospective Studies
TL;DR:
It is suggested that where E911 locations are available, they offer an improvement upon address-matched geocodes for rural addresses, and that exposure misclassification resulting from positional error can be minimized when known coordinates are available to test alternative data and methods.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Association between Class III Obesity (BMI of 40–59 kg/m2) and Mortality: A Pooled Analysis of 20 Prospective Studies
PLoS Medicine, 11(7), e1001673.
Contributors: C. Kitahara *, A. Flint*, A. Gonzalez *, L. Bernstein *, M. Brotzman*, R. MacInnis *, S. Moore *, K. Robien *
Ed(s): K. Khaw
MeSH headings : Australia / epidemiology; Body Mass Index; Humans; Life Expectancy; Obesity / mortality; Prospective Studies; Risk Factors; Sweden / epidemiology; United States / epidemiology
TL;DR:
In a pooled analysis of 20 prospective studies, Cari Kitahara and colleagues find that class III obesity is associated with excess rates of total mortality, particularly due to heart disease, cancer, and diabetes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2014 journal article
Is Helicobacter Pylori an endogenous source of diethyl phthalate in humans?
Environmental Research, 134, 402–404.
author keywords: Diethyl phthalate; Monoethyl phthalate; Helicobacter pylori; NHANES; Microbiome
MeSH headings : Adolescent; Adult; Female; Helicobacter pylori / metabolism; Humans; Male; Middle Aged; Phthalic Acids / metabolism; Young Adult
TL;DR:
Results suggest that HP may be an endogenous source of DEP in some populations, and MEP levels were higher in individuals with HP seropositivity, however the association differed by race.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Long-Term Exposure to Fine Particulate Matter: Association with Nonaccidental and Cardiovascular Mortality in the Agricultural Health Study Cohort
Environmental Health Perspectives, 122(6), 609–615.
Contributors: S. Weichenthal *, P. Villeneuve *, R. Burnett *, A. Donkelaar *, R. Martin *, R. Jones *, C. DellaValle *, D. Sandler *, M. Ward *, *
MeSH headings : Adult; Agriculture / statistics & numerical data; Air Pollutants / analysis; Air Pollutants / toxicity; Cardiovascular Diseases / mortality; Cohort Studies; Environmental Exposure / analysis; Environmental Exposure / statistics & numerical data; Female; Humans; Iowa / epidemiology; Male; Mortality; North Carolina / epidemiology; Particulate Matter / analysis; Particulate Matter / toxicity; Risk Factors; Rural Population; Sex Factors
TL;DR:
Positive associations were observed between ambient PM2.5 and cardiovascular mortality among men, and these associations were strongest among men who did not move from their enrollment address, while similar associations were not observed among women.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2014 journal article
Non-Hodgkin Lymphoma Risk and Insecticide, Fungicide and Fumigant Use in the Agricultural Health Study
PLoS ONE, 9(10), e109332.
Ed(s): S. Akiba
MeSH headings : Adult; Aged; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Agriculture; Fungicides, Industrial / toxicity; Humans; Hydrocarbons, Chlorinated / toxicity; Insecticides / toxicity; Iowa; Leukemia, Lymphocytic, Chronic, B-Cell / chemically induced; Leukemia, Lymphocytic, Chronic, B-Cell / epidemiology; Leukemia, Lymphocytic, Chronic, B-Cell / pathology; Lymphoma, Non-Hodgkin / chemically induced; Lymphoma, Non-Hodgkin / epidemiology; Lymphoma, Non-Hodgkin / pathology; Middle Aged; Multiple Myeloma / chemically induced; Multiple Myeloma / epidemiology; Multiple Myeloma / pathology; North Carolina; Risk Factors
TL;DR:
Findings are among the first to suggest links between DDT, lindane, permethrin, diazinon and terbufos with NHL subtypes, but not all members of any single class of pesticides were associated with an elevated risk of NHL or NHL sub types.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020
2014 journal article
Obesity and the cardiovascular health effects of fine particulate air pollution
Obesity, 22(7), 1580–1589.
Contributors: S. Weichenthal *, n & F. Reeves *
MeSH headings : Air Pollution / adverse effects; Air Pollution / statistics & numerical data; Cardiovascular Diseases / mortality; Causality; Cause of Death; Cohort Studies; Comorbidity; Environmental Monitoring / statistics & numerical data; Female; Humans; Longitudinal Studies; Male; Obesity / mortality; Particulate Matter / toxicity; Prospective Studies; Public Health; Weather
TL;DR:
This review examines evidence related to the potential impact of obesity on the cardiovascular health effects of fine particulate air pollution (PM2.5).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Peptidoglycan recognition protein genes and risk of Parkinson's disease
Movement Disorders, 29(9), 1171–1180.
Contributors: S. Goldman *, F. Kamel *, G. Ross*, S. Jewell *, C. Marras *, n , D. Umbach *, G. Bhudhikanok*
author keywords: Parkinson's disease; peptidoglycan; PGLYRP; microbiome; gut
MeSH headings : Adult; Aged; Aged, 80 and over; Carrier Proteins / genetics; Case-Control Studies; Female; Genetic Association Studies; Genetic Predisposition to Disease / genetics; Genotype; Humans; Logistic Models; Male; Microbiota / genetics; Middle Aged; Odds Ratio; Parkinson Disease / genetics; Polymorphism, Single Nucleotide / genetics
TL;DR:
Common variants in PGLYRP genes are associated with PD risk in two independent studies and are consistent with hypotheses of a causative role for the gut microbiota and gastrointestinal immune response in PD.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, NC State University Libraries, Crossref, NC State University Libraries
Added: August 6, 2018
2014 journal article
Perfluoroalkyl Substances During Pregnancy and Validated Preeclampsia Among Nulliparous Women in the Norwegian Mother and Child Cohort Study
American Journal of Epidemiology, 179(7), 824–833.
Contributors: A. Starling *, S. Engel, D. Richardson, D. Baird *, L. Haug *, A. Stuebe, K. Klungsøyr *, Q. Harmon *
author keywords: Norwegian Mother and Child Cohort Study; perfluoroalkyl substances; perfluorooctanoic acid; perfluorooctane sulfonate; perfluoroundecanoic acid; preeclampsia
MeSH headings : Adolescent; Adult; Alkanesulfonic Acids / blood; Caprylates / blood; Cohort Studies; Environmental Exposure / adverse effects; Environmental Exposure / analysis; Environmental Pollutants / adverse effects; Environmental Pollutants / blood; Fatty Acids / blood; Female; Fluorocarbons / blood; Humans; Norway; Parity; Pre-Eclampsia / blood; Pre-Eclampsia / etiology; Pregnancy; Proportional Hazards Models; Young Adult
TL;DR:
The findings do not support an increased risk of preeclampsia among nulliparous Norwegian women with background levels of PFAS exposure, and an inverse association between preeClampsia and the highest quartile of perfluoroundecanoic acid concentration relative to the lowest quartile is found.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2014 journal article
Perfluoroalkyl substances and lipid concentrations in plasma during pregnancy among women in the Norwegian Mother and Child Cohort Study
Environment International, 62, 104–112.
Contributors: A. Starling *, S. Engel *, K. Whitworth *, D. Richardson *, A. Stuebe *, J. Daniels *, L. Haug *, M. Eggesbø *
author keywords: The Norwegian Mother and Child Cohort Study MoBa; Perfluoroalkyl substances; Perfluorooctanoic acid; Perfluorooctane sulfonate
MeSH headings : Adult; Alkanesulfonic Acids / blood; Cholesterol / blood; Cohort Studies; Cross-Sectional Studies; Environmental Pollutants / blood; Female; Fluorocarbons / blood; Humans; Linear Models; Lipids / blood; Mothers; Norway
TL;DR:
Plasma concentrations of PFASs were positively associated with HDL cholesterol, and PFOS was positivelyassociated with total cholesterol in this sample of pregnant Norwegian women, suggesting a mechanism by which PFAS exposure leads to certain adverse pregnancy outcomes, including preeclampsia.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2014 journal article
Pesticide Exposure and Depression among Male Private Pesticide Applicators in the Agricultural Health Study
Environmental Health Perspectives, 122(9), 984–991.
MeSH headings : Adult; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Depression / chemically induced; Depression / epidemiology; Hazardous Substances / metabolism; Humans; Hydrocarbons, Chlorinated / metabolism; Iowa / epidemiology; Logistic Models; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / statistics & numerical data; Odds Ratio; Organophosphorus Compounds / metabolism; Pesticides / metabolism; Risk Factors; Young Adult
TL;DR:
A positive association between pesticide exposure and depression among male private pesticide applicators in the Agricultural Health Study is supported, including associations with several specific pesticides.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020
2014 journal article
Pesticide use and incident diabetes among wives of farmers in the Agricultural Health Study
Occupational and Environmental Medicine, 71(9), 629–635.
Contributors: A. Starling *, D. Umbach *, F. Kamel *, S. Long*, D. Sandler * & n
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Diabetes Mellitus / epidemiology; Diabetes Mellitus / etiology; Female; Humans; Incidence; Iowa / epidemiology; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Organophosphates / toxicity; Pesticides / toxicity; Proportional Hazards Models; Spouses; Young Adult
TL;DR:
Results are consistent with previous studies reporting an association between specific organochlorines and diabetes and add to growing evidence that certain organophosphates also may increase risk, though attenuated compared with separate models.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Prevalence of allergic sensitization in the United States: Results from the National Health and Nutrition Examination Survey (NHANES) 2005-2006
Journal of Allergy and Clinical Immunology, 134(2), 350–359.
Contributors: P. Salo *, S. Arbes Jr., R. Jaramillo*, A. Calatroni *, C. Weir*, M. Sever *, * , K. Rose*
author keywords: Allergen; allergy; allergic sensitization; serum IgE
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Allergens / immunology; Child; Child, Preschool; Cross Reactions; Cross-Sectional Studies; Female; Food Hypersensitivity / blood; Food Hypersensitivity / epidemiology; Food Hypersensitivity / ethnology; Food Hypersensitivity / immunology; Humans; Immunoglobulin E / blood; Infant; Male; Middle Aged; Nutrition Surveys; Prevalence; Racial Groups; Respiratory Hypersensitivity / blood; Respiratory Hypersensitivity / epidemiology; Respiratory Hypersensitivity / ethnology; Respiratory Hypersensitivity / immunology; United States / epidemiology
TL;DR:
The overall prevalence of allergic sensitization does not vary across US census regions, except in early life, although allergen-specific sensitization differs based on sociodemographic and regional factors.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2014 journal article
Protective glove use and hygiene habits modify the associations of specific pesticides with Parkinson's disease
Environment International, 75, 144–150.
author keywords: Personal protective equipment; Parkinson's disease; Pesticides; Neurodegenerative diseases; Movement disorders
MeSH headings : Adult; Aged; Aged, 80 and over; Agriculture; Case-Control Studies; Female; Gloves, Protective / statistics & numerical data; Habits; Humans; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Occupational Exposure / prevention & control; Occupational Health; Paraquat; Parkinson Disease / epidemiology; Parkinson Disease / etiology; Permethrin; Pesticides; Risk; Rotenone; Surveys and Questionnaires; Trifluralin; Workplace
TL;DR:
Although sample size was limited in the FAME study, protective glove use and hygiene practices appeared to be important modifiers of the association between pesticides and PD and may reduce risk of PD associated with certain pesticides.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Reliability of triclosan measures in repeated urine samples from Norwegian pregnant women
Journal of Exposure Science & Environmental Epidemiology, 24(5), 517–521.
Contributors: R. Bertelsen *, S. Engel *, T. Jusko *, A. Calafat *, * , S. London *, M. Eggesbø *, H. Aase *
author keywords: biomarkers; MoBa; intraclass correlation coefficient; pregnancy; reliability; triclosan
MeSH headings : Anti-Infective Agents, Local / urine; Female; Humans; Norway; Pregnancy; Reproducibility of Results; Triclosan / urine
TL;DR:
The reliability of TCS concentrations in repeated urine samples from pregnant Norwegian women was reasonably good, suggesting a single urine sample can adequately represent TCS exposure during pregnancy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2014 journal article
Respiratory disease in United States farmers
Occupational and Environmental Medicine, 71(7), 484–491.
Contributors: * , D. Umbach *, S. Long*, J. Rinsky*, P. Henneberger *, P. Salo *, D. Zeldin *, S. London *
MeSH headings : Adult; Aged; Aged, 80 and over; Agriculture; Air Pollutants / adverse effects; Asthma / epidemiology; Asthma / etiology; Cough / epidemiology; Cough / etiology; Female; Humans; Iowa / epidemiology; Male; Middle Aged; Mucus / metabolism; North Carolina / epidemiology; Nutrition Surveys; Occupational Diseases / epidemiology; Occupational Diseases / etiology; Occupational Exposure / adverse effects; Prevalence; Prospective Studies; Respiration Disorders / epidemiology; Respiration Disorders / etiology; Respiratory Sounds / etiology; Risk Factors; Sex Factors; Spouses; Young Adult
TL;DR:
Findings suggest that farmers and their spouses have lower risk for adult-onset respiratory diseases compared with the general population, and potentially higher respiratory irritation as evidenced by increased respiratory symptoms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Single-Nucleotide Polymorphism Data Support the General Unrelatedness of the Males in the Agricultural Health Study
Cancer Epidemiology Biomarkers & Prevention, 23(10), 2192–2195.
MeSH headings : Agriculture; Case-Control Studies; Cohort Studies; Consanguinity; Gene-Environment Interaction; Humans; Male; Occupational Exposure; Polymorphism, Single Nucleotide; Principal Component Analysis; Research Design
TL;DR:
This analysis rejects the hypothesis that individuals in the case–control study of prostate cancer exhibit cryptic relatedness, and these findings are important for all subsequent analyses of gene–environment interactions in the AHS.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2013 journal article
A-clustering: a novel method for the detection of co-regulated methylation regions, and regions associated with exposure
Bioinformatics, 29(22), 2884–2891.
Contributors: T. Sofer *, E. Schifano *, * , L. Hou * & A. Baccarelli *
MeSH headings : Algorithms; Cluster Analysis; CpG Islands; DNA Methylation; Environmental Exposure; Humans
TL;DR:
An analysis pipeline for high-dimensional methylation data in which CpG sites within regions identified by A-clustering are modeled as multivariate responses to environmental exposure using a generalized estimating equation approach that assumes exposure equally affects all sites in the cluster.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2013 journal article
Agricultural Exposures and Stroke Mortality in the Agricultural Health Study
Journal of Toxicology and Environmental Health, Part A, 76(13), 798–814.
Contributors: J. Rinsky*, * , A. Blair*, K. He*, L. Beane Freeman* & H. Chen *
MeSH headings : Aged; Agricultural Workers' Diseases / etiology; Agricultural Workers' Diseases / mortality; Agriculture / statistics & numerical data; Female; Humans; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Pesticides / adverse effects; Proportional Hazards Models; Prospective Studies; Risk Factors; Spouses; Stroke / etiology; Stroke / mortality; Surveys and Questionnaires; Survival Rate
TL;DR:
The authors evaluated associations between self-reported agricultural activities including pesticide use and handling of crops and stroke mortality among 51,603 male pesticide applicators enrolled in the Agricultural Health Study (AHS).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2013 journal article
Arsenic Exposure and Incidence of Type 2 Diabetes in Southwestern American Indians
American Journal of Epidemiology, 177(9), 962–969.
author keywords: arsenic; diabetes mellitus; type 2; incidence; Indians; North American; nested case-control studies
MeSH headings : Adult; Albuminuria / urine; Arizona / epidemiology; Arsenic / adverse effects; Arsenic / urine; Biomarkers / urine; Case-Control Studies; Creatinine / urine; Diabetes Mellitus, Type 2 / ethnology; Diabetes Mellitus, Type 2 / etiology; Diabetes Mellitus, Type 2 / urine; Drinking Water / chemistry; Environmental Exposure / adverse effects; Environmental Exposure / analysis; Female; Glucose Tolerance Test; Humans; Incidence; Indians, North American / statistics & numerical data; Logistic Models; Longitudinal Studies; Male; Odds Ratio; Prevalence; Water Pollutants, Chemical / adverse effects; Water Pollutants, Chemical / analysis
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2013 journal article
Association between Perfluoroalkyl substances and thyroid stimulating hormone among pregnant women: a cross-sectional study
Environmental Health, 12(1).
Contributors: Y. Wang *, A. Starling *, L. Haug *, M. Eggesbo *, G. Becher*, C. Thomsen *, G. Travlos*, D. King*
author keywords: Perfluorinated alkyl substances; Thyroid stimulating hormone; Pregnant women; The Norwegian Mother and child cohort study; MoBa
MeSH headings : Adolescent; Adult; Alkanes / blood; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Environmental Exposure; Environmental Monitoring; Environmental Pollutants / blood; Female; Fluorocarbons / blood; Humans; Immunoassay; Linear Models; Norway; Odds Ratio; Pregnancy; Tandem Mass Spectrometry; Thyrotropin / blood; Young Adult
TL;DR:
An association between PFOS and TSH in pregnant women is suggested that is small and may be of no clinical significance, and other PFASs were unrelated to TSH.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2013 journal article
Determinants of plasma concentrations of perfluoroalkyl substances in pregnant Norwegian women
Environment International, 54, 74–84.
Contributors: A. Brantsæter *, K. Whitworth *, T. Ydersbond*, L. Haug *, M. Haugen *, H. Knutsen *, C. Thomsen *, H. Meltzer *
author keywords: Perfluoroalkyl substances; Reproductive history; Pregnancy; Dietary exposure
MeSH headings : Adult; Alkanesulfonic Acids / blood; Cohort Studies; Diet / statistics & numerical data; Environmental Pollutants / blood; Female; Fluorocarbons / blood; Humans; Maternal Exposure / statistics & numerical data; Norway; Pregnancy
TL;DR:
Previous pregnancies and breastfeeding duration were the most important determinants of PFASs in this sample of pregnant women, and diet was a significant factor explaining up to 4% of the variance.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2013 journal article
Dietary fat intake, pesticide use, and Parkinson's disease
Parkinsonism & Related Disorders, 20(1), 82–87.
Contributors: F. Kamel *, S. Goldman *, D. Umbach *, H. Chen *, G. Richardson*, M. Barber*, C. Meng*, C. Marras *
author keywords: Parkinson's disease; Dietary fat; Polyunsaturated fatty acids; Pesticides
MeSH headings : Adult; Aged; Aged, 80 and over; Case-Control Studies; Diet; Dietary Fats; Fatty Acids, Omega-3; Female; Humans; Male; Middle Aged; Parkinson Disease / epidemiology; Pesticides / adverse effects; Risk Factors
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2013 journal article
Exacerbation of symptoms in agricultural pesticide applicators with asthma
International Archives of Occupational and Environmental Health, 87(4), 423–432.
Contributors: P. Henneberger *, X. Liang*, S. London *, D. Umbach *, D. Sandler * & *
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / etiology; Asthma, Occupational / epidemiology; Asthma, Occupational / etiology; Female; Humans; Male; Middle Aged; Occupational Exposure / adverse effects; Pesticides / adverse effects; Risk Factors; Severity of Illness Index; Surveys and Questionnaires; United States; Young Adult
TL;DR:
The inverse associations with two pesticides and specific farm activities are consistent with the possibility that asthma cases prone to exacerbation may avoid exposures that trigger symptoms, and suggest that use of specific pesticides may contribute to exacerbate of asthma among individuals with allergies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2013 journal article
Genetic Susceptibility Loci, Pesticide Exposure and Prostate Cancer Risk
PLoS ONE, 8(4), e58195.
Contributors: S. Koutros *, S. Berndt *, K. Hughes Barry *, G. Andreotti *, * , D. Sandler *, M. Yeager *, L. Burdett*
Ed(s): M. Scheurer
MeSH headings : Adult; Aged; Aged, 80 and over; Case-Control Studies; Environmental Exposure; Gene-Environment Interaction; Genetic Loci; Genetic Predisposition to Disease; Genome-Wide Association Study; Humans; Male; Middle Aged; Neoplasm Grading; Neoplasm Staging; Odds Ratio; Pesticides / adverse effects; Polymorphism, Single Nucleotide; Prospective Studies; Prostatic Neoplasms / etiology; Prostatic Neoplasms / pathology; Risk; Young Adult
TL;DR:
This study suggests known genetic susceptibility loci may modify the risk between pesticide use and prostate cancer.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2013 journal article
Hypothyroidism and Pesticide Use Among Male Private Pesticide Applicators in the Agricultural Health Study
Journal of Occupational and Environmental Medicine, 55(10), 1171–1178.
MeSH headings : Adult; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Agriculture; Humans; Hypothyroidism / chemically induced; Hypothyroidism / epidemiology; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / statistics & numerical data; Pesticides / adverse effects; Prospective Studies; Surveys and Questionnaires
TL;DR:
There is an association between hypothyroidism and specific herbicides and insecticides in male applicators, similar to previous results for spouses.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2013 journal article
Joint effects between five identified risk variants, allergy, and autoimmune conditions on glioma risk
Cancer Causes & Control, 24(10), 1885–1891.
Contributors: M. Safaeian*, P. Rajaraman *, P. Hartge*, M. Yeager *, M. Linet *, M. Butler*, A. Ruder*, M. Purdue *
author keywords: Single-nucleotide polymorphisms; Glioma; Allergies; Autoimmune conditions; Gene-environment interaction
MeSH headings : Aged; Autoimmune Diseases / epidemiology; Autoimmune Diseases / genetics; Autoimmune Diseases / immunology; Brain Neoplasms / epidemiology; Brain Neoplasms / genetics; Brain Neoplasms / immunology; Case-Control Studies; Female; Gene-Environment Interaction; Genetic Predisposition to Disease; Glioma / epidemiology; Glioma / genetics; Glioma / immunology; Humans; Hypersensitivity / epidemiology; Hypersensitivity / genetics; Hypersensitivity / immunology; Male; Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; United States / epidemiology
TL;DR:
The results do not provide evidence that allergies or AIC modulate the association between the four GWAS-identified SNPs examined and risk of glioma.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2013 journal article
Lifetime Pesticide Use and Telomere Shortening among Male Pesticide Applicators in the Agricultural Health Study
Environmental Health Perspectives, 121(8), 919–924.
Contributors: L. Hou *, G. Andreotti *, A. Baccarelli *, S. Savage *, * , D. Sandler *, J. Barker, Z. Zhu *
author keywords: Agricultural Health Study; cancer-free subjects; occupational exposures; pesticides; telomere length
MeSH headings : Adult; Aged; Aged, 80 and over; Agriculture; DDT / toxicity; Humans; Iowa; Male; Middle Aged; Mouth Mucosa / chemistry; Mouth Mucosa / drug effects; North Carolina; Occupational Exposure; Pesticides / toxicity; Prospective Studies; Real-Time Polymerase Chain Reaction; Telomere Shortening / drug effects
TL;DR:
Seven pesticides previously associated with cancer risk in the epidemiologic literature were inversely associated with RTL in buccal cell DNA among cancer-free pesticide applicators.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2013 journal article
Pesticide Exposure and Inherited Variants in Vitamin D Pathway Genes in Relation to Prostate Cancer
Cancer Epidemiology Biomarkers & Prevention, 22(9), 1557–1566.
Contributors: S. Karami *, G. Andreotti *, S. Koutros *, K. Barry *, L. Moore *, S. Han *, * , D. Sandler *
MeSH headings : Aged; Aged, 80 and over; Apoptosis / drug effects; Apoptosis / genetics; Case-Control Studies; Cell Growth Processes / drug effects; Cell Growth Processes / genetics; Cohort Studies; Genotype; Humans; Male; Middle Aged; Pesticides / poisoning; Polymorphism, Single Nucleotide; Prostatic Neoplasms / chemically induced; Prostatic Neoplasms / epidemiology; Prostatic Neoplasms / genetics; Risk Factors; Surveys and Questionnaires; United States / epidemiology; Vitamin D / genetics; Vitamin D / metabolism
TL;DR:
Genetic variations in vitamin D pathway genes, particularly GC rs7041, an SNP previously linked to lower circulating vitamin D levels, modified pesticide associations with prostate cancer risk are examined.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2013 journal article
Pesticide exposure and self-reported incident depression among wives in the Agricultural Health Study
Environmental Research, 126, 31–42.
Contributors: J. Beard *, * , M. Richards*, M. Alavanja*, A. Blair*, D. Sandler *, F. Kamel *
author keywords: Depression; Female; Incidence; Pesticides; Spouses
MeSH headings : Adult; Depression / chemically induced; Depression / epidemiology; Female; Humans; Iowa / epidemiology; Middle Aged; North Carolina / epidemiology; Pesticides / toxicity; Prospective Studies; Spouses / statistics & numerical data
TL;DR:
This study adds further evidence that high level pesticide exposure, such as pesticide poisoning, is associated with increased risk of depression and sets a lower bound on the level of exposure related to depression, thereby providing reassurance that the moderate levels of pesticide exposure experienced by farmers' wives likely do not increase risk.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2013 journal article
Pesticides and respiratory health: where do we go from here?
Occupational and Environmental Medicine, 71(2), 80–80.
MeSH headings : Air Pollutants, Occupational / toxicity; Female; Humans; Male; Occupational Exposure / adverse effects; Pesticides / toxicity; Pulmonary Disease, Chronic Obstructive / chemically induced
TL;DR:
It is reported that occupational pesticide exposure is associated with poorer pulmonary function consistent with airway obstruction as measured by spirometry in two Dutch general population cohorts.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2013 journal article
Phthalate Exposure and Allergy in the U.S. Population: Results from NHANES 2005–2006
Environmental Health Perspectives, 121(10), 1129–1134.
Contributors: * , R. Jaramillo*, S. London *, R. Bertelsen *, P. Salo *, D. Sandler *, D. Zeldin *
MeSH headings : Adolescent; Adult; Child; Cross-Sectional Studies; Environmental Exposure / adverse effects; Environmental Exposure / analysis; Female; Humans; Hypersensitivity / etiology; Immune System / drug effects; Logistic Models; Male; Phthalic Acids / toxicity; Phthalic Acids / urine; United States; Young Adult
TL;DR:
HMW phthalate metabolites, particularly MBzP, were positively associated with allergic symptoms and sensitization in adults, but there was no strong evidence for associations between phthalates and allergy in children 6–17 years of age.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2013 journal article
The concentration of bisphenol A in urine is affected by specimen collection, a preservative, and handling
Environmental Research, 126, 211–214.
Contributors: M. Longnecker *, K. Harbak*, G. Kissling*, * , M. Eggesbo *, T. Jusko *, J. Eide, H. Koch *
author keywords: Bisphenol A; Urine specimen collection; Contamination
MeSH headings : Adult; Benzhydryl Compounds / urine; Female; Humans; Phenols / urine; Pregnancy; Specimen Handling
TL;DR:
Under the conditions used to collect urine specimens in the epidemiologic study, contamination with BPA occurred, and by two separate mechanisms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Consumer product exposures associated with urinary phthalate levels in pregnant women
Journal of Exposure Science & Environmental Epidemiology, 22(5), 468–475.
Contributors: J. Buckley *, R. Palmieri*, J. Matuszewski*, A. Herring *, D. Baird *, K. Hartmann *, *
author keywords: phthalates; pregnancy; biomonitoring; urine; personal care products
MeSH headings : Adolescent; Adult; Cosmetics / adverse effects; Female; Household Articles; Household Products / adverse effects; Humans; Perfume / adverse effects; Phthalic Acids / metabolism; Phthalic Acids / urine; Pregnancy; Surveys and Questionnaires; Young Adult
TL;DR:
Although personal care product use may be an important predictor of urinaryphthalate levels, most of the variability in phthalate exposure was not captured by the relatively comprehensive set of questionnaire items.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Exposure to Tobacco Smoke in Utero and Subsequent Plasma Lipids, ApoB, and CRP among Adult Women in the MoBa Cohort
Environmental Health Perspectives, 120(11), 1532–1537.
Contributors: L. Cupul-Uicab *, R. Skjaerven *, K. Haug*, G. Travlos*, R. Wilson*, M. Eggesbø *, * , K. Whitworth *, M. Longnecker *
author keywords: clinical chemistry; C-reactive protein; metabolic syndrome; plasma lipids; prenatal exposure delayed effects; smoking; women
MeSH headings : Adolescent; Adult; Biomarkers / blood; C-Reactive Protein / metabolism; Cohort Studies; Female; Humans; Lipids / blood; Metabolic Syndrome / blood; Metabolic Syndrome / chemically induced; Metabolic Syndrome / epidemiology; Norway / epidemiology; Pregnancy; Prenatal Exposure Delayed Effects / blood; Prenatal Exposure Delayed Effects / chemically induced; Prenatal Exposure Delayed Effects / epidemiology; Risk Factors; Smoking / adverse effects; Smoking / epidemiology; Tobacco Smoke Pollution / adverse effects; Young Adult
TL;DR:
In this population of pregnant women, in utero exposure to tobacco smoke was associated with high triglycerides and low HDL in adulthood, 18–44 years after exposure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Farming activities and carrying and lifting: The agricultural health study
Journal of Physical Activity and Health, 9(1), 39–47. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862940731&partnerID=MN8TOARS
Source: ORCID
Added: September 13, 2019
2012 journal article
Fungal and atopic sensitization are low among farmers in the Agricultural Health Study
Journal of Allergy and Clinical Immunology, 130(1), 267–270.e1.
Contributors: S. Endres *, B. Green*, P. Henneberger *, D. Germolec *, T. Bledsoe*, D. Beezhold *, S. London *, M. Alavanja*, L. Beane Freeman *, *
MeSH headings : Agricultural Workers' Diseases / diagnosis; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / etiology; Agricultural Workers' Diseases / immunology; Agriculture; Fungi / classification; Fungi / immunology; Humans; Hypersensitivity, Immediate / diagnosis; Hypersensitivity, Immediate / epidemiology; Hypersensitivity, Immediate / etiology; Hypersensitivity, Immediate / immunology; Immunoglobulin E / blood; Male; Prevalence; Surveys and Questionnaires
TL;DR:
Prevalence of fungal sensitization and atopy was lower among farmers than the US population and related to growing specific agricultural commodities.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Genetic modification of the association of paraquat and Parkinson's disease
Movement Disorders, 27(13), 1652–1658.
Contributors: S. Goldman *, F. Kamel *, G. Ross*, G. Bhudhikanok*, * , M. Korell*, C. Marras *, C. Meng*
author keywords: Parkinson's disease; paraquat; glutathione transferase; pesticide; gene-environment interaction
MeSH headings : Age Factors; Aged; Aged, 80 and over; Case-Control Studies; Cohort Studies; Diagnosis, Computer-Assisted; Disease Susceptibility / chemically induced; Disease Susceptibility / epidemiology; Female; Gene Deletion; Genetic Association Studies; Genotype; Glutathione Transferase / genetics; Herbicides / toxicity; Humans; Male; Middle Aged; Occupational Exposure; Paraquat / toxicity; Parkinson Disease, Secondary / chemically induced; Parkinson Disease, Secondary / epidemiology; Parkinson Disease, Secondary / genetics; Risk Factors; Surveys and Questionnaires
TL;DR:
The results suggest that PD risk from paraquat exposure might be particularly high in individuals lacking GSTT1, which is common and could potentially identify a large subpopulation at high risk of PD from oxidative stressors such as paraquats.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Lifetime organophosphorous insecticide use among private pesticide applicators in the Agricultural Health Study
Journal of Exposure Science & Environmental Epidemiology, 22(6), 584–592.
Contributors: * , S. Long*, D. Umbach *, J. Lubin *, S. Starks*, F. Gerr*, K. Thomas *, C. Hines*
author keywords: pesticide use; farming; organophosphorous insecticide
MeSH headings : Aged; Aged, 80 and over; Humans; Insecticides; Middle Aged; North Carolina; Organophosphorus Compounds; Private Sector
TL;DR:
Information on farmers’ OP use enhances the ability to characterize and understand the potential health effects of multiple OP exposures, and much of the variability in OP use was associated with the choice of OP, rather than the frequency or duration of application.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Methyl bromide exposure and cancer risk in the Agricultural Health Study
Cancer Causes & Control, 23(6), 807–818.
Contributors: K. Barry *, S. Koutros *, J. Lubin *, J. Coble*, F. Barone-Adesi *, L. Beane Freeman *, D. Sandler *, *
author keywords: Methyl bromide; Fumigant; Pesticide; Cancer
MeSH headings : Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Agriculture; Cohort Studies; Confidence Intervals; Female; Follow-Up Studies; Herbicides / poisoning; Humans; Hydrocarbons, Brominated / poisoning; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Occupational Exposure / statistics & numerical data; Poisson Distribution; Risk Factors; Stomach Neoplasms / chemically induced; Stomach Neoplasms / epidemiology; Surveys and Questionnaires
TL;DR:
The results provide little evidence of methyl bromide associations with cancer risk for most sites examined; however, it is observed that a significant exposure-dependent increase in stomach cancer risk is observed.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
P60—Preliminary results on subfecundity and plasma concentrations of perfluorinated compounds during pregnancy in the Norwegian Mother and Child Cohort Study, 2002–2004
Reproductive Toxicology, 33(4), 620–621.
Sources: Crossref, NC State University Libraries
Added: September 10, 2020
2012 journal article
Perfluorinated Compounds in Relation to Birth Weight in the Norwegian Mother and Child Cohort Study
American Journal of Epidemiology, 175(12), 1209–1216.
Contributors: K. Whitworth *, L. Haug *, D. Baird *, G. Becher*, * , R. Skjaerven *, C. Thomsen *, M. Eggesbo *
author keywords: birth weight; MoBa; Norwegian Mother and Child Cohort Study; perfluorinated compounds; perfluorooctane sulfonate; perfluorooctanoic acid
MeSH headings : Adult; Alkanesulfonic Acids / blood; Alkanesulfonic Acids / toxicity; Birth Weight / drug effects; Caprylates / blood; Caprylates / toxicity; Diet Surveys; Environmental Pollutants / blood; Environmental Pollutants / toxicity; Female; Fetal Macrosomia / chemically induced; Fluorocarbons / blood; Fluorocarbons / toxicity; Food Contamination; Humans; Infant, Newborn; Infant, Small for Gestational Age; Maternal Exposure / adverse effects; Norway; Odds Ratio; Pregnancy; Premature Birth / chemically induced; Prospective Studies; Seafood; Single-Blind Method
TL;DR:
Perfluorooctane sulfonate and perfluorOOctanoic acid were each associated with decreased adjusted odds of preterm birth, although the cell counts were small.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Peripheral Nervous System Function and Organophosphate Pesticide Use among Licensed Pesticide Applicators in the Agricultural Health Study
Environmental Health Perspectives, 120(4), 515–520.
Contributors: S. Starks*, * , F. Kamel *, C. Lynch, M. Jones *, M. Alavanja*, D. Sandler *, F. Gerr*
author keywords: agricultural workers; neurological testing; occupational exposure; organophosphates; pesticide exposure
MeSH headings : Aged; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / physiopathology; Confounding Factors, Epidemiologic; Follow-Up Studies; Health Surveys; Humans; Iowa / epidemiology; Male; Middle Aged; Nervous System Diseases / chemically induced; Nervous System Diseases / epidemiology; Nervous System Diseases / physiopathology; North Carolina / epidemiology; Occupational Exposure; Odds Ratio; Organophosphorus Compounds / toxicity; Peripheral Nervous System / drug effects; Peripheral Nervous System / physiopathology; Pesticides / toxicity; Prospective Studies; Regression Analysis; Surveys and Questionnaires
TL;DR:
Evidence is provided that long-term exposure to OP pesticides is associated with signs of impaired PNS function among pesticide applicators, and mostly null associations were observed between OP pesticide use and electrophysiological tests, hand strength, sway speed, and vibrotactile threshold.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Pesticide exposure and amyotrophic lateral sclerosis
NeuroToxicology, 33(3), 457–462.
Contributors: F. Kamel *, D. Umbach *, R. Bedlack *, M. Richards*, M. Watson*, M. Alavanja*, A. Blair*, * , S. Schmidt *, D. Sandler *
author keywords: Amyotrophic lateral sclerosis; Motor neuron disease; Cohort study; Meta-analysis; Pesticides; Organochlorine insecticides
TL;DR:
The meta-analysis suggests that ALS risk is associated with use of pesticides as a group, and the analysis of AHS data points to OC use in particular.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Pesticide use and fatal injury among farmers in the Agricultural Health Study
International Archives of Occupational and Environmental Health, 86(2), 177–187.
Contributors: J. Waggoner*, P. Henneberger *, G. Kullman*, D. Umbach *, F. Kamel *, L. Beane Freeman *, M. Alavanja*, D. Sandler *, *
author keywords: Pesticides; Mortality; Wounds and injuries
MeSH headings : Accidents, Occupational / mortality; Accidents, Occupational / statistics & numerical data; Adult; Aged; Agriculture; Confidence Intervals; Gloves, Protective; Health Surveys; Humans; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Occupational Exposure / statistics & numerical data; Pesticides / adverse effects; Proportional Hazards Models; Risk Factors; Surveys and Questionnaires; Time Factors
TL;DR:
The association between application of pesticides, particularly certain herbicides, and fatal injuries among farmers should be interpreted cautiously but deserves further evaluation, with particular focus on understanding timing of pesticide use and fatal injury.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Poultry and livestock exposure and cancer risk among farmers in the agricultural health study
Cancer Causes & Control, 23(5), 663–670.
Contributors: L. Beane Freeman *, A. DeRoos*, S. Koutros *, A. Blair*, M. Ward *, M. Alavanja*, *
author keywords: Livestock; Poultry; Cancer; Cohort study; Agriculture
MeSH headings : Adult; Aged; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Agrochemicals / poisoning; Air Pollutants, Occupational / poisoning; Animal Husbandry; Animals; Cohort Studies; Humans; Incidence; Livestock; Male; Middle Aged; Neoplasms / chemically induced; Neoplasms / epidemiology; Occupational Exposure / adverse effects; Occupational Exposure / statistics & numerical data; Poultry; Risk Factors; United States / epidemiology
TL;DR:
An inverse association between raising poultry and livestock and lung cancer risk and some evidence of increased risk of specific lymphohematopoietic malignancies with specific types of animals and performing veterinary services is observed.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Risk of Total and Aggressive Prostate Cancer and Pesticide Use in the Agricultural Health Study
American Journal of Epidemiology, 177(1), 59–74.
author keywords: aggressive prostate cancer; cohort study; farming; organophosphate insecticides; pesticide exposure; prostate cancer
MeSH headings : Age Factors; Aged; Agriculture / statistics & numerical data; Health Behavior; Herbicides / toxicity; Humans; Insecticides / toxicity; Male; Middle Aged; Organophosphorus Compounds / toxicity; Prostatic Neoplasms / chemically induced; Prostatic Neoplasms / physiopathology; Racial Groups; Severity of Illness Index
TL;DR:
This analysis has overcome several limitations of previous studies with the inclusion of a large number of cases with relevant exposure and detailed information on use of specific pesticides at 2 points in time, and for the first time specific pesticides are implicated as risk factors for aggressive prostate cancer.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Risk-Accepting Personality and Personal Protective Equipment Use Within the Agricultural Health Study
Journal of Agromedicine, 17(3), 264–276.
Contributors: C. DellaValle *, * , C. Hines*, G. Andreotti * & M. Alavanja
author keywords: Agricultural Health Study; personal protective equipment; pesticide; risk-accepting behavior
MeSH headings : Agriculture; Follow-Up Studies; Humans; Iowa; Male; Middle Aged; North Carolina; Occupational Exposure / prevention & control; Occupational Exposure / statistics & numerical data; Personality; Pesticides / toxicity; Protective Clothing; Protective Devices; Risk Factors; Surveys and Questionnaires; Workforce
TL;DR:
Findings suggest that the decisions to use personal protective equipment and properly handle/apply pesticides may be driven by risk-accepting personality traits.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 13, 2019
2012 journal article
The Interaction between Pesticide Use and Genetic Variants Involved in Lipid Metabolism on Prostate Cancer Risk
Journal of Cancer Epidemiology, 2012, 1–11.
Contributors: G. Andreotti *, S. Koutros *, S. Berndt *, K. Hughes Barry *, L. Hou *, * , D. Sandler *, J. Lubin *
TL;DR:
Genetic variation in lipid metabolism genes may modify pesticide associations with prostate cancer; however, results require replication.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Urinary Biomarkers for Phthalates Associated with Asthma in Norwegian Children
Environmental Health Perspectives, 121(2), 251–256.
Contributors: R. Bertelsen *, K. LØdrup Carlsen *, A. Calafat *, * , G. Håland*, P. Mowinckel*, K. Carlsen *, M. LØvik*
author keywords: asthma; biomarkers; children; endocrine disruptors; phthalates
MeSH headings : Asthma / chemically induced; Biomarkers / urine; Body Burden; Child; Cross-Sectional Studies; Humans; Norway; Phthalic Acids / pharmacokinetics; Phthalic Acids / toxicity; Phthalic Acids / urine
TL;DR:
Current asthma was associated with the highest quartiles of MCOP and MCNP, metabolites of two high molecular weight phthalates, diisononylphthalate and diisodecyl phthalate, respectively.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Using multiple imputation to assign pesticide use for non-responders in the follow-up questionnaire in the Agricultural Health Study
Journal of Exposure Science & Environmental Epidemiology, 22(4), 409–416.
Contributors: S. Heltshe *, J. Lubin *, S. Koutros *, J. Coble*, B. Ji*, M. Alavanja, A. Blair*, D. Sandler *
author keywords: agriculture; cohort studies; missing data; pesticides; precision
MeSH headings : Agriculture; Follow-Up Studies; Humans; Pesticides; Surveys and Questionnaires
TL;DR:
When appropriately implemented, multiple imputation can reduce bias and increase precision and can be more valid than other missing data approaches.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2011 journal article
AGRICOH: A Consortium of Agricultural Cohorts
International Journal of Environmental Research and Public Health, 8(5), 1341–1357.
Contributors: M. Leon *, L. Beane Freeman *, J. Douwes *, * , H. Kromhout *, P. Lebailly*, K. Nordby *, M. Schenker *
author keywords: agriculture; cohort studies; consortium, pesticides; occupational exposures
MeSH headings : Agricultural Workers' Diseases; Agriculture; Cohort Studies; Humans; International Cooperation; Occupational Exposure
TL;DR:
Altogether, AGRICOH provides excellent opportunities for studying cancer, respiratory, neurologic, and auto-immune diseases as well as reproductive and allergic disorders, injuries and overall mortality in association with a wide array of exposures, prominent among these the application of pesticides.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2011 journal article
Allergy-related outcomes in relation to serum IgE: Results from the National Health and Nutrition Examination Survey 2005-2006
Journal of Allergy and Clinical Immunology, 127(5), 1226–1235.e7.
Contributors: P. Salo *, A. Calatroni *, P. Gergen*, * , M. Sever *, R. Jaramillo *, S. Arbes Jr., D. Zeldin *
author keywords: Allergen; allergy; allergic sensitization; serum IgE
MeSH headings : Allergens / immunology; Animals; Antibody Specificity; Cats; Cattle; Cross-Sectional Studies; Dogs; Female; Fungi / immunology; Humans; Hypersensitivity, Immediate / epidemiology; Hypersensitivity, Immediate / immunology; Immunoglobulin E / blood; Male; Mice; Nutrition Surveys; Pets / immunology; Plants / immunology; Prevalence; Rats; Rhinitis, Allergic, Seasonal / epidemiology; Rhinitis, Allergic, Seasonal / immunology; Surveys and Questionnaires; United States / epidemiology
TL;DR:
In the US population self-reported allergy symptoms are most consistently associated with increased levels of plant-, pet-, and mold-specific IgE, which contributed independently to allergy-related symptoms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2011 journal article
An Updated Algorithm for Estimation of Pesticide Exposure Intensity in the Agricultural Health Study
International Journal of Environmental Research and Public Health, 8(12), 4608–4622.
Contributors: J. Coble*, K. Thomas *, C. Hines*, * , M. Dosemeci*, B. Curwin*, J. Lubin *, L. Freeman *
author keywords: pesticides; exposure algorithm; epidemiology; 2,4-D; chlorpyrifos; captan
MeSH headings : Agriculture; Algorithms; Environmental Exposure; Humans; Pesticides / toxicity
TL;DR:
The weighting factors for the revised algorithm now incorporate exposure measurements taken on Agricultural Health Study (AHS) participants for the application methods and personal protective equipment (PPE) commonly reported by study participants.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2011 journal article
Atrazine and Cancer Incidence Among Pesticide Applicators in the Agricultural Health Study (1994–2007)
Environmental Health Perspectives, 119(9), 1253–1259.
Contributors: L. Beane Freeman *, J. Rusiecki *, * , J. Lubin *, S. Koutros *, G. Andreotti *, S. Zahm*, C. Hines*
author keywords: agriculture; atrazine; cancer; cohort study; epidemiology; pesticide
MeSH headings : Adult; Aged; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Atrazine / toxicity; Carcinogens / toxicity; Cohort Studies; Confidence Intervals; Female; Herbicides / adverse effects; Humans; Iowa / epidemiology; Male; Middle Aged; Neoplasms / chemically induced; Neoplasms / epidemiology; North Carolina / epidemiology; Odds Ratio; Poisson Distribution; Prospective Studies; Surveys and Questionnaires; Thyroid Neoplasms / chemically induced; Thyroid Neoplasms / epidemiology
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2011 journal article
Genetic Variation in Base Excision Repair Pathway Genes, Pesticide Exposure, and Prostate Cancer Risk
Environmental Health Perspectives, 119(12), 1726–1732.
Contributors: K. Barry *, S. Koutros *, S. Berndt *, G. Andreotti *, * , D. Sandler *, L. Burdette *, M. Yeager *
author keywords: DNA repair; gene-environment interactions; pesticide; polymorphisms; prostate cancer
MeSH headings : Case-Control Studies; DNA Repair / genetics; Fonofos / adverse effects; Genetic Variation; Genotype; Humans; Likelihood Functions; Logistic Models; Male; N-Glycosyl Hydrolases / genetics; North Carolina / epidemiology; Occupational Exposure / adverse effects; Odds Ratio; Pesticides / adverse effects; Polymorphism, Single Nucleotide / genetics; Prostatic Neoplasms / chemically induced; Prostatic Neoplasms / epidemiology; Prostatic Neoplasms / genetics; Risk Assessment
TL;DR:
A role of BER genetic variation in pesticide-associated prostate cancer risk is suggested in a nested case–control study of white Agricultural Health Study pesticide applicators.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 13, 2019
2011 journal article
Head injury, alpha-synuclein Rep1, and Parkinson's disease
Annals of Neurology, 71(1), 40–48.
Contributors: S. Goldman *, F. Kamel *, G. Ross*, S. Jewell *, G. Bhudhikanok*, D. Umbach *, C. Marras *, R. Hauser *
MeSH headings : Adult; Aged; Aged, 80 and over; Case-Control Studies; Cohort Studies; Craniocerebral Trauma / blood; Craniocerebral Trauma / epidemiology; Craniocerebral Trauma / genetics; Female; Genetic Variation; Humans; Male; Microsatellite Repeats / genetics; Middle Aged; Neurodegenerative Diseases / blood; Neurodegenerative Diseases / epidemiology; Neurodegenerative Diseases / genetics; Parkinson Disease / diagnosis; Parkinson Disease / epidemiology; Parkinson Disease / genetics; Prospective Studies; alpha-Synuclein / biosynthesis; alpha-Synuclein / blood; alpha-Synuclein / genetics
TL;DR:
To test the hypothesis that variability in SNCA Rep1, a polymorphic dinucleotide microsatellite in the promoter region of the gene encoding α‐synuclein, modifies the association between head injury and Parkinson's disease (PD) risk, a single-satellite approach is used.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2011 journal article
High pesticide exposure events and central nervous system function among pesticide applicators in the Agricultural Health Study
International Archives of Occupational and Environmental Health, 85(5), 505–515.
Contributors: S. Starks*, F. Gerr*, F. Kamel *, C. Lynch *, M. Alavanja*, D. Sandler *, *
author keywords: Agricultural workers; Epidemiology; Neurobehavioral testing; Pesticide exposure; High pesticide exposure event
MeSH headings : Aged; Aged, 80 and over; Agriculture; Central Nervous System / drug effects; Humans; Iowa; Linear Models; Male; Middle Aged; North Carolina; Occupational Diseases / chemically induced; Occupational Diseases / diagnosis; Occupational Exposure / adverse effects; Occupational Exposure / analysis; Pesticides / poisoning; Prospective Studies; Surveys and Questionnaires
TL;DR:
One or more HPEE may contribute to adverse CNS outcomes independent of diagnosed pesticide poisoning, and no significant associations were observed between participants who ever had an HPEE and the remaining neurobehavioral tests.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2011 journal article
Impact of pesticide exposure misclassification on estimates of relative risks in the Agricultural Health Study
Occupational and Environmental Medicine, 68(7), 537–541.
Contributors: A. Blair*, K. Thomas *, J. Coble*, D. Sandler *, C. Hines*, C. Lynch *, C. Knott *, M. Purdue *
MeSH headings : 2,4-Dichlorophenoxyacetic Acid / urine; Agriculture / statistics & numerical data; Algorithms; Biomarkers / urine; Environmental Monitoring / methods; Humans; Occupational Exposure / adverse effects; Occupational Exposure / analysis; Occupational Exposure / statistics & numerical data; Pesticides / toxicity; Prospective Studies; Pyridones / urine; Risk Assessment / methods
TL;DR:
Findings indicate that a priori expert-derived algorithm scores were more closely related to measured urinary levels than individual exposure determinants evaluated here, which indicates that non-differential misclassification of exposure would bias relative risk estimates in the AHS towards the null and diminish study power.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2011 journal article
Is rigorous retrospective harmonization possible? Application of the DataSHaPER approach across 53 large studies
International Journal of Epidemiology, 40(5), 1314–1328.
author keywords: Data synthesis; data quality; data pooling; harmonization; meta-analysis; DataSHaPER; retrospective harmonization
MeSH headings : Chronic Disease / epidemiology; Cohort Studies; Data Collection / methods; Data Interpretation, Statistical; Databases, Factual; Epidemiologic Methods; Humans; Retrospective Studies; Risk Factors; Surveys and Questionnaires
TL;DR:
The current article shows that the DataSHaPER provides an effective and flexible approach for the retrospective harmonization of information across studies and offers the promise of enhanced research potential generated through synthesized databases.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 28, 2021
2011 journal article
Job Activities and Respiratory Symptoms Among Farmworkers in North Carolina
Archives of Environmental & Occupational Health, 66(3), 178–182.
Contributors: M. Mirabelli *, * , A. Chatterjee *, S. Isom *, H. Chen *, J. Grzywacz *, T. Howard *, S. Quandt *, Q. Vallejos*, T. Arcury *
author keywords: agriculture; asthma; epidemiology; occupational lung disease; respiratory diseases
MeSH headings : Age Factors; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / etiology; Agriculture / statistics & numerical data; Female; Humans; Logistic Models; Male; North Carolina / epidemiology; Occupational Exposure / adverse effects; Occupational Exposure / statistics & numerical data; Prevalence; Respiratory Sounds; Respiratory Tract Diseases / epidemiology; Respiratory Tract Diseases / etiology; Smoking / adverse effects; Smoking / epidemiology; Surveys and Questionnaires
TL;DR:
Though not statistically significant, the odds of wheezing were elevated for individuals who reported performing tobacco-related work in the last 3 days and the odds were decreased among individuals who report harvesting activities.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2011 journal article
Neurobehavioral function and organophosphate insecticide use among pesticide applicators in the Agricultural Health Study
Neurotoxicology and Teratology, 34(1), 168–176.
Contributors: S. Starks*, F. Gerr*, F. Kamel *, C. Lynch *, M. Jones *, M. Alavanja, D. Sandler *, *
author keywords: Agricultural workers; Epidemiology; Organophosphates; Neuropsychological testing; Pesticide exposure
MeSH headings : Aged; Agriculture; Cognition Disorders / diagnosis; Cognition Disorders / epidemiology; Cognition Disorders / physiopathology; Cohort Studies; Comorbidity / trends; Humans; Male; Middle Aged; Neurotoxicity Syndromes / diagnosis; Neurotoxicity Syndromes / epidemiology; Neurotoxicity Syndromes / physiopathology; Organophosphate Poisoning; Organophosphates / classification; Pesticides / classification; Pesticides / poisoning; Prospective Studies
TL;DR:
Overall, it is found that there is no consistent evidence of an association between OP pesticide use and adverse NB test performance among this older sample of pesticide applicators, and several associations varied by state.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2011 journal article
Neurologic Symptoms Associated With Raising Poultry and Swine Among Participants in the Agricultural Health Study
Journal of Occupational and Environmental Medicine, 53(2), 190–195.
Contributors: M. Davis *, F. Kamel *, * , M. Alavanja*, L. Freeman*, G. Gray *, K. Nelson*, E. Silbergeld *
MeSH headings : Adult; Agricultural Workers' Diseases / diagnosis; Agricultural Workers' Diseases / epidemiology; Alcohol Drinking / epidemiology; Animals; Female; Guillain-Barre Syndrome / epidemiology; Humans; Hypesthesia / diagnosis; Hypesthesia / epidemiology; Male; Middle Aged; Muscle Weakness / diagnosis; Muscle Weakness / epidemiology; Nervous System Diseases / diagnosis; Nervous System Diseases / epidemiology; Poultry; Prevalence; Smoking / epidemiology; Swine
TL;DR:
Occupational contact with live poultry or swine, potentially related to C. jejuni exposure, was associated with increased reporting of GBS-like symptoms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2011 journal article
Perfluorinated Compounds and Subfecundity in Pregnant Women
Epidemiology, 23(2), 257–263.
Contributors: K. Whitworth *, L. Haug, D. Baird, G. Becher, * , R. Skjaerven, C. Thomsen, M. Eggesbo
MeSH headings : Adult; Alkanesulfonic Acids / adverse effects; Alkanesulfonic Acids / blood; Body Burden; Caprylates / adverse effects; Caprylates / blood; Case-Control Studies; Female; Fertility / drug effects; Fluorocarbons / adverse effects; Fluorocarbons / blood; Gas Chromatography-Mass Spectrometry; Humans; Logistic Models; Norway / epidemiology; Odds Ratio; Parity; Pregnancy / drug effects
TL;DR:
The results among nulliparous women did not support an association with subfecundity, and previous studies suggest that the body burden of perfluorinated compounds decreases during pregnancy and lactation through transfer to the fetus and to breast milk.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2011 journal article
Questionnaire Predictors of Atopy in a US Population Sample: Findings From the National Health and Nutrition Examination Survey, 2005-2006
American Journal of Epidemiology, 173(5), 544–552.
Contributors: * , R. Jaramillo*, P. Salo *, D. Sandler *, S. London * & D. Zeldin *
author keywords: hypersensitivity; immunoglobulin E; questionnaires; sensitivity and specificity
MeSH headings : Adolescent; Adult; Biomarkers / blood; Child; Child, Preschool; Eczema / epidemiology; Eczema / immunology; Female; Health Surveys / statistics & numerical data; Humans; Hypersensitivity / epidemiology; Hypersensitivity / immunology; Hypersensitivity, Immediate / epidemiology; Immunoglobulin E / blood; Immunologic Factors / blood; Infant; Male; Middle Aged; Nutrition Surveys / statistics & numerical data; Predictive Value of Tests; Rhinitis, Allergic, Seasonal / epidemiology; Sampling Studies; Sensitivity and Specificity; Surveys and Questionnaires; United States / epidemiology
TL;DR:
To assess questionnaires' ability to predict biochemical measures of atopy, the authors used data on 5 allergic conditions and serum-specific immunoglobulin E (IgE) levels from the 2005-2006 National Health and Nutrition Examination Survey to identify participants found to be atopic by biochemical measures.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2011 journal article
Rotenone, Paraquat, and Parkinson’s Disease
Environmental Health Perspectives, 119(6), 866–872.
Contributors: C. Tanner *, F. Kame *, G. Ross*, * , S. Goldman *, M. Korell*, C. Marras *, G. Bhudhikanok*
author keywords: aging; agricultural epidemiology; environmental epidemiology; epidemiology; fungicides; herbicides; insecticides; persistent organic pollutants; pesticides
MeSH headings : Aged; Case-Control Studies; Female; Herbicides / toxicity; Humans; Insecticides / toxicity; Iowa / epidemiology; Male; Middle Aged; Mitochondria / metabolism; North Carolina / epidemiology; Occupational Exposure; Oxidative Stress; Paraquat / toxicity; Parkinson Disease / epidemiology; Parkinson Disease / etiology; Parkinsonian Disorders / epidemiology; Parkinsonian Disorders / etiology; Rotenone / toxicity
TL;DR:
PD was positively associated with two groups of pesticides defined by mechanisms implicated experimentally—those that impair mitochondrial function and those that increase oxidative stress—supporting a role for these mechanisms in PD pathophysiology.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2011 journal article
Suicide and Pesticide Use among Pesticide Applicators and Their Spouses in the Agricultural Health Study
Environmental Health Perspectives, 119(11), 1610–1615.
Contributors: J. Beard *, D. Umbach *, * , M. Richards*, M. Alavanja, A. Blair*, D. Sandler *, F. Kamel *
author keywords: farmers; pesticide applicators; pesticides; spouses; suicide
MeSH headings : Adult; Aged; Cause of Death; Cohort Studies; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Health Surveys; Humans; Incidence; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure; Pesticides / toxicity; Proportional Hazards Models; Prospective Studies; Risk Factors; Socioeconomic Factors; Spouses; Suicide / statistics & numerical data; Surveys and Questionnaires; Young Adult
TL;DR:
Findings do not support an association between moderate pesticide use and suicide in applicators and their spouses, and were consistent across several measures of pesticide use.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2011 journal article
Xenobiotic-metabolizing gene variants, pesticide use, and the risk of prostate cancer
Pharmacogenetics and Genomics, 21(10), 615–623.
Contributors: S. Koutros *, G. Andreotti *, S. Berndt *, K. Hughes Barry *, J. Lubin *, * , F. Kamel *, D. Sandler *
author keywords: interaction; pesticides; prostate cancer; single nucleotide polymorphism; xenobiotic-metabolizing enzymes
MeSH headings : Alleles; Epoxide Hydrolases / genetics; Genetic Association Studies; Glutamate-Cysteine Ligase / genetics; Humans; Logistic Models; Male; Occupational Exposure; Oxidative Stress / genetics; Peroxidase / genetics; Pesticides / adverse effects; Polymorphism, Single Nucleotide; Prostatic Neoplasms / genetics; Risk Factors; Thioredoxin Reductase 2 / genetics; Xenobiotics / metabolism
TL;DR:
The number of observed interactions in XMEs was comparable with the number expected by chance alone, and several pesticide–SNP interactions in oxidative stress and phase I/II enzyme genes and risk of prostate cancer were observed.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2010 journal article
An Update of Cancer Incidence in the Agricultural Health Study
Journal of Occupational and Environmental Medicine, 52(11), 1098–1105.
Contributors: S. Koutros *, M. Alavanja, J. Lubin *, D. Sandler *, * , C. Lynch *, C. Knott *, A. Blair*, L. Freeman *
MeSH headings : Adult; Aged; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Air Pollutants, Occupational / adverse effects; Female; Humans; Incidence; Male; Middle Aged; Neoplasms / chemically induced; Neoplasms / epidemiology; North Carolina / epidemiology; Occupational Exposure / adverse effects; Pesticides / adverse effects; Prospective Studies; Registries; Spouses / statistics & numerical data
TL;DR:
Although lower rates of smoking and increased physical activity probably contribute to the lower overall cancer incidence, agricultural exposures including pesticides, viruses, bacteria, sunlight, and other chemicals may increase risks for specific cancer sites.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2010 journal article
Body mass index, agricultural pesticide use, and cancer incidence in the Agricultural Health Study cohort
Cancer Causes & Control, 21(11), 1759–1775.
Contributors: G. Andreotti *, L. Hou *, L. Beane Freeman *, R. Mahajan*, S. Koutros *, J. Coble*, J. Lubin *, A. Blair*, * , M. Alavanja*
author keywords: Obesity; Body mass index; Pesticides; Cancer; Agriculture
MeSH headings : Agriculture; Body Mass Index; Breast Neoplasms / complications; Breast Neoplasms / epidemiology; Cohort Studies; Colonic Neoplasms / complications; Colonic Neoplasms / epidemiology; Female; Humans; Incidence; Male; Neoplasms / epidemiology; Neoplasms / etiology; Obesity / complications; Obesity / epidemiology; Overweight / epidemiology; Pesticides / adverse effects; Prospective Studies; Surveys and Questionnaires
TL;DR:
It is suggested that certain pesticides may modify the effects of BMI on the risks of colon and lung cancers and not in non-users of these pesticides.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2010 journal article
Body mass index, effect modifiers, and risk of pancreatic cancer: a pooled study of seven prospective cohorts
Cancer Causes & Control, 21(8), 1305–1314.
Contributors: L. Jiao *, A. Berrington De Gonzalez *, P. Hartge*, R. Pfeiffer *, Y. Park *, D. Freedman*, M. Gail *, M. Alavanja
author keywords: Pancreatic cancer; Body mass index; Pooled analysis; Prospective cohort; Effect modification
MeSH headings : Age Factors; Body Mass Index; Cohort Studies; Effect Modifier, Epidemiologic; Female; Humans; Male; Middle Aged; Pancreatic Neoplasms / epidemiology; Pancreatic Neoplasms / etiology; Proportional Hazards Models; Prospective Studies; Risk Factors; Sex Factors
TL;DR:
The present evidence suggests that a high BMI is an independent risk factor of pancreatic cancer.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2010 journal article
Body-Mass Index and Mortality among 1.46 Million White Adults
New England Journal of Medicine, 363(23), 2211–2219.
Contributors: A. De Gonzalez *, P. Hartge*, J. Cerhan *, A. Flint*, L. Hannan*, R. MacInnis *, S. Moore *, G. Tobias *
MeSH headings : Adult; Body Mass Index; Cause of Death; Confounding Factors, Epidemiologic; Exercise; Female; Follow-Up Studies; Humans; Male; Mortality / ethnology; Overweight / mortality; Proportional Hazards Models; Smoking / adverse effects; Socioeconomic Factors; Thinness / mortality; White People / statistics & numerical data
TL;DR:
In white adults, overweight and obesity (and possibly underweight) are associated with increased all-cause mortality and the hazard ratios for the men were similar.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2010 journal article
Identification of Iowa Live Births in the Agricultural Health Study
Archives of Environmental & Occupational Health, 65(3), 154–162.
Contributors: P. Romitti *, S. Watanabe-Galloway, W. Budelier*, C. Lynch *, S. Puzhankara*, D. Wong-Gibbons*, * , M. Alavanja*
author keywords: children; occupational exposures; pesticides; pregnancy; prospective cohort
MeSH headings : Agricultural Workers' Diseases / epidemiology; Agriculture / statistics & numerical data; Birth Certificates; Family Characteristics; Female; Health Surveys; Humans; Iowa / epidemiology; Live Birth / epidemiology; Male; Occupational Exposure / adverse effects; Occupational Exposure / statistics & numerical data; Parity; Pregnancy
TL;DR:
A probabilistic and deterministic approach was used to link available demographic data from 31,707 households and information on live births from 13,599 households with 1,014,916 Iowa birth certificates, producing an expanded cohort of live-born children among Iowa participants.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2010 journal article
Maternal Pesticide Use and Birth Weight in the Agricultural Health Study
Journal of Agromedicine, 15(2), 127–136.
Contributors: S. Sathyanarayana *, O. Basso *, C. Karr *, P. Lozano *, M. Alavanja*, D. Sandler *, *
author keywords: Agricultural exposures; birth weight; carbaryl; pesticides; reproductive epidemiology
MeSH headings : Adolescent; Adult; Agriculture; Carbaryl / adverse effects; Female; Health Surveys; Humans; Infant, Low Birth Weight; Infant, Newborn; Insecticides / adverse effects; Iowa; Male; Maternal Exposure / adverse effects; Middle Aged; Mothers; North Carolina; Occupational Exposure / adverse effects; Occupational Health; Pregnancy; Pregnancy Trimester, First / metabolism; Young Adult
TL;DR:
Overall, the authors observed no associations between birth weight and pesticide-related activities during early pregnancy and have no data on temporal specificity of individual pesticide exposures prior to or during pregnancy and therefore cannot draw conclusions related to these exposure windows.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2010 journal article
Mortality in the Agricultural Health Study, 1993-2007
American Journal of Epidemiology, 173(1), 71–83.
Contributors: J. Waggoner*, G. Kullman, P. Henneberger, D. Umbach, A. Blair, M. Alavanja, F. Kamel, C. Lynch
author keywords: agriculture; healthy worker effect; mortality; neoplasms; pesticides; wounds and injuries
MeSH headings : Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / mortality; Cause of Death / trends; Female; Humans; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Pesticides / adverse effects; Retrospective Studies; Survival Rate / trends
TL;DR:
Using data from the Agricultural Health Study, a cohort of 89,656 pesticide applicators and their spouses in North Carolina and Iowa, standardized mortality ratios (SMRs) were computed comparing deaths from time of the enrollment through 2007 to state-specific rates.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2010 journal article
Occupational exposure to terbufos and the incidence of cancer in the Agricultural Health Study
Cancer Causes & Control, 21(6), 871–877.
Contributors: M. Bonner *, B. Williams *, J. Rusiecki *, A. Blair*, L. Beane Freeman *, * , M. Dosemeci*, J. Lubin *, D. Sandler *, M. Alavanja*
author keywords: Cancer incidence; Terbufos; Organophosphate insecticides
MeSH headings : Agriculture; Carcinogens; Data Collection; Humans; Incidence; Insecticides; Iowa / epidemiology; Leukemia / complications; Leukemia / epidemiology; Lymphoma, Non-Hodgkin / complications; Lymphoma, Non-Hodgkin / epidemiology; Male; Neoplasms / complications; Neoplasms / epidemiology; Nervous System Neoplasms / complications; Nervous System Neoplasms / epidemiology; North Carolina / epidemiology; Occupational Exposure / statistics & numerical data; Organophosphorus Compounds; Organothiophosphorus Compounds; Patients; Pesticides; Surveys and Questionnaires
TL;DR:
C cautious interpretation of these results is warranted by the lack of existing experimental and epidemiologic evidence to support carcinogenic effects of terbufos, but suggestive associations between occupational ter bufos use and several cancer sites are found.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2010 journal article
Pesticide Exposures and Uterine Fibroid Risk Among Farming Women
Annals of Epidemiology, 20(9), 707.
Sources: Crossref, NC State University Libraries
Added: September 10, 2020
2010 journal article
Pesticide Use Modifies the Association Between Genetic Variants on Chromosome 8q24 and Prostate Cancer
Cancer Research, 70(22), 9224–9233.
Contributors: S. Koutros *, L. Beane Freeman *, S. Berndt *, G. Andreotti *, J. Lubin *, D. Sandler *, * , K. Yu *
MeSH headings : Adult; Aged; Chromosomes, Human, Pair 8 / genetics; Coumaphos / poisoning; Fonofos / poisoning; Genome-Wide Association Study; Humans; Incidence; Iowa / epidemiology; Logistic Models; Male; Middle Aged; North Carolina / epidemiology; Occupational Diseases / chemically induced; Occupational Diseases / epidemiology; Occupational Diseases / genetics; Odds Ratio; Organothiophosphorus Compounds / poisoning; Permethrin / poisoning; Pesticides / poisoning; Phorate / poisoning; Polymorphism, Single Nucleotide; Prospective Studies; Prostatic Neoplasms / chemically induced; Prostatic Neoplasms / epidemiology; Prostatic Neoplasms / genetics; Risk Assessment; Risk Factors
TL;DR:
A significant interaction among variants on chromosome 8q24, pesticide use, and risk of prostate cancer was observed, and Insecticides, particularly organophosphates, were the strongest modifiers of risk, although the biological mechanism is unclear.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2010 journal article
Pesticide Use and Myocardial Infarction Incidence Among Farm Women in the Agricultural Health Study
Journal of Occupational and Environmental Medicine, 52(7), 693–697.
Contributors: S. Dayton*, D. Sandler *, A. Blair*, M. Alavanja*, L. Beane Freeman * & *
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Female; Humans; Incidence; Iowa / epidemiology; Middle Aged; Myocardial Infarction / chemically induced; Myocardial Infarction / epidemiology; North Carolina / epidemiology; Occupational Exposure; Pesticides / adverse effects; Prospective Studies; Risk Factors; Women's Health; Young Adult
TL;DR:
Pesticides may contribute to MI risk among farm women and six of 27 individual pesticides evaluated were significantly associated with nonfatal MI, including chlorpyrifos, coumaphos, carbofuran, metalaxyl, pendimethalin, and trifluralin.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2010 journal article
Pesticide Use and Thyroid Disease Among Women in the Agricultural Health Study
American Journal of Epidemiology, 171(4), 455–464.
Contributors: W. Goldner *, D. Sandler *, F. Yu *, * , F. Kamel * & T. Levan *
author keywords: agriculture; environmental exposure; hyperthyroidism; hypothyroidism; pesticides; thyroid gland
MeSH headings : Agriculture; Cross-Sectional Studies; Environmental Exposure; Female; Fumigation / adverse effects; Fungicides, Industrial / toxicity; Herbicides / toxicity; Humans; Iowa / epidemiology; Logistic Models; North Carolina / epidemiology; Pesticides / toxicity; Prevalence; Prospective Studies; Spouses; Thyroid Diseases / chemically induced; Thyroid Diseases / epidemiology
TL;DR:
Data support a role of organochlorines, in addition to fungicides, in the etiology of thyroid disease among female spouses enrolled in the Agricultural Health Study.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2010 journal article
Rhinitis Associated with Pesticide Use Among Private Pesticide Applicators in the Agricultural Health Study
Journal of Toxicology and Environmental Health, Part A, 73(20), 1382–1393.
Contributors: R. Slager*, S. Simpson *, T. Levan *, J. Poole *, D. Sandler * & *
MeSH headings : Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Animals; Captan; Cohort Studies; Diazinon; Female; Humans; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Odds Ratio; Pesticides / adverse effects; Pesticides / classification; Petroleum; Rhinitis / chemically induced; Rhinitis / epidemiology; Risk Factors; Surveys and Questionnaires; Time Factors; Young Adult
TL;DR:
Specific pesticides may contribute to rhinitis in farmers; agricultural activities did not explain these findings.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2009 journal article
Assessment of a pesticide exposure intensity algorithm in the agricultural health study
Journal of Exposure Science & Environmental Epidemiology, 20(6), 559–569.
Contributors: K. Thomas *, M. Dosemeci*, J. Coble*, * , L. Sheldon*, G. Chapa*, C. Croghan*, P. Jones *
author keywords: 2,4-D; chlorpyrifos; exposure measurement; occupational exposure; Agricultural Health Study
MeSH headings : 2,4-Dichlorophenoxyacetic Acid / analysis; 2,4-Dichlorophenoxyacetic Acid / urine; Agriculture; Air Pollutants, Occupational / analysis; Air Pollutants, Occupational / urine; Algorithms; Biomarkers / urine; Chlorpyrifos / analysis; Chlorpyrifos / urine; Cohort Studies; Environmental Exposure / analysis; Environmental Monitoring / methods; Gas Chromatography-Mass Spectrometry; Humans; Iowa; Linear Models; North Carolina; Occupational Exposure / analysis; Pesticides / analysis; Pesticides / urine; Risk Assessment / methods; Skin Absorption; Surveys and Questionnaires
TL;DR:
The results of the measurements support the use of the algorithm for estimating questionnaire-based exposure intensities in the AHS for liquid pesticide products and refine the algorithm may be possible using the results from this and other measurement studies.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2009 journal article
Cancer Incidence Among Paraquat Exposed Applicators in the Agricultural Health Study: A Prospective Cohort Study
International Journal of Occupational and Environmental Health, 15(3), 274–281.
Contributors: S. Park *, D. Kang, L. Beane-Freeman, A. Blair, * , D. Sandler, C. Lynch, C. Knott, J. Gwak, M. Alavanja
MeSH headings : Adult; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Female; Herbicides / toxicity; Humans; Incidence; Iowa / epidemiology; Lymphoma, Non-Hodgkin / chemically induced; Lymphoma, Non-Hodgkin / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Paraquat / toxicity; Prospective Studies; Risk
TL;DR:
There was some suggestion of a possible link between paraquat exposure and NHL risk in humans, but the inconsistency in exposure level trend suggests that this could be a chance finding.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Crossref, ORCID
Added: September 13, 2019
2009 journal article
Cancer Incidence Among Pesticide Applicators Exposed to Methyl Bromide in the AHS
Annals of Epidemiology, 19(9), 662–663.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 10, 2020
2009 journal article
Cancer incidence among pesticide applicators exposed to butylate in the Agricultural Health Study (AHS)
Environmental Research, 109(7), 860–868.
Contributors: S. Lynch *, R. Mahajan*, L. Beane Freeman *, * & M. Alavanja*
author keywords: Butylate; Pesticide; Cancer; Agricultural Health Study
MeSH headings : Adult; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Cohort Studies; Female; Humans; Iowa / epidemiology; Lymphoma, Non-Hodgkin / chemically induced; Lymphoma, Non-Hodgkin / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Pesticides / poisoning; Prevalence; Prospective Studies; Prostatic Neoplasms / chemically induced; Prostatic Neoplasms / epidemiology; Surveys and Questionnaires; Thiocarbamates / poisoning
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2009 journal article
Coumaphos Exposure and Incident Cancer among Male Participants in the Agricultural Health Study (AHS)
Environmental Health Perspectives, 118(1), 92–96.
Contributors: C. Christensen*, E. Platz *, G. Andreotti *, A. Blair*, * , S. Koutros *, C. Lynch *, D. Sandler *, M. Alavanja*
author keywords: agriculture; cancer; coumaphos; insecticide; livestock; neoplasms; occupational exposure; organophosphate; pesticide; prostate
MeSH headings : Adult; Aged; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / etiology; Animal Husbandry; Cohort Studies; Coumaphos / administration & dosage; Coumaphos / toxicity; Genetic Predisposition to Disease; Humans; Insecticides / administration & dosage; Insecticides / toxicity; Iowa / epidemiology; Male; Middle Aged; Neoplasms / epidemiology; Neoplasms / etiology; North Carolina / epidemiology; Occupational Exposure; Occupational Health; Prospective Studies; Prostatic Neoplasms / epidemiology; Prostatic Neoplasms / etiology; Prostatic Neoplasms / genetics; Risk Assessment; Surveys and Questionnaires; Young Adult
TL;DR:
Cumulative exposure to coumaphos was not associated with cancer risk overall or with any major cancer site including prostate, and there was evidence of an association between cou maphos and prostate cancer, possibly due to genetic susceptibility; however, other explanations are plausible.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2009 journal article
Effects of self-reported health conditions and pesticide exposures on probability of follow-up in a prospective cohort study
American Journal of Industrial Medicine, 53(5), n/a-n/a.
Contributors: M. Montgomery *, F. Kamel *, * , L. Freeman *, M. Alavanja* & D. Sandler *
author keywords: selection bias; follow-up studies; prospective studies; cohort studies; pesticides; agriculture
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agriculture; Confidence Intervals; Female; Humans; Iowa / epidemiology; Logistic Models; Male; Middle Aged; Multivariate Analysis; North Carolina / epidemiology; Occupational Diseases / epidemiology; Occupational Diseases / etiology; Occupational Exposure / adverse effects; Odds Ratio; Patient Acceptance of Health Care; Pesticides / toxicity; Probability; Prospective Studies; Risk Assessment; Risk Factors; Selection Bias; Surveys and Questionnaires; Time Factors; United States / epidemiology; Young Adult
TL;DR:
Differences between non-participants and participants in the follow-up interview were generally small, and significant evidence of selection bias was found, however, the extent of bias may depend on the specific exposure and outcome under study.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2009 journal article
Levels of metabolites of organophosphate pesticides, phthalates, and bisphenol A in pooled urine specimens from pregnant women participating in the Norwegian Mother and Child Cohort Study (MoBa)
International Journal of Hygiene and Environmental Health, 212(5), 481–491.
Contributors: X. Ye *, F. Pierik*, J. Angerer*, H. Meltzer *, V. Jaddoe *, H. Tiemeier *, * , M. Longnecker *
author keywords: Organophosphate (OP) pesticides; Bisphenol A (BPA); Phthalates; Biological monitoring; Environmental exposure
MeSH headings : Adolescent; Adult; Benzhydryl Compounds; Cohort Studies; Environmental Exposure / analysis; Female; Humans; Middle Aged; Norway; Organophosphates / urine; Pesticides / urine; Phenols / urine; Phthalic Acids / urine; Pregnancy
TL;DR:
The higher levels of metabolites in the MoBa participants may have been from intake via pesticide residues in food, consumption of canned food, especially fish/seafood (BPA), and use of personal care products (selected phthalates).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2009 journal article
Occupational Exposure to Metribuzin and the Incidence of Cancer in the Agricultural Health Study
Annals of Epidemiology, 19(6), 388–395.
Contributors: J. Delancey *, M. Alavanja*, J. Coble*, A. Blair*, * , H. Austin*, L. Beane Freeman *
author keywords: Pesticides; Cancer; Occupation; Metribuzin; Agricultural Health Study
MeSH headings : Adult; Aged; Agriculture; Carcinogens / toxicity; Cohort Studies; Female; Hematologic Neoplasms / epidemiology; Herbicides / toxicity; Humans; Iowa / epidemiology; Leukemia / epidemiology; Lymphoma / epidemiology; Male; Middle Aged; Neoplasms / epidemiology; North Carolina / epidemiology; Occupational Exposure / analysis; Risk Factors; Surveys and Questionnaires; Triazines / toxicity
TL;DR:
A potential association between metribuzin use and certain lymphohematopoietic malignancies is suggested, however, having not been observed previously, caution should be used in interpretation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2009 journal article
Occupational Risk Factors for Rhinitis Among Farmers in the Agricultural Health Study
Journal of Allergy and Clinical Immunology, 123(2), S266–S266.
TL;DR:
Handling hays and grains as well as farm maintenance activities may increase the risk of rhinitis in farmers.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 10, 2020
2009 journal article
Pesticide Exposure and Hypertensive Disorders During Pregnancy
Environmental Health Perspectives, 117(9), 1393–1396.
author keywords: pesticide exposure; preeclampsia; pregnancy-induced hypertension
MeSH headings : Adolescent; Adult; Environmental Exposure; Female; Humans; Hypertension / chemically induced; Hypertension / complications; Middle Aged; Pesticides / toxicity; Pregnancy; Pregnancy Complications, Cardiovascular / chemically induced
TL;DR:
Exposure to pesticides during pregnancy may increase the risk of hypertensive disorders of pregnancy, including pregnancy-induced hypertension (PIH) and preeclampsia (PE).
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2009 journal article
Pesticide exposure and risk of monoclonal gammopathy of undetermined significance in the Agricultural Health Study
Blood, 113(25), 6386–6391.
Contributors: O. Landgren *, R. Kyle *, * , L. Beane Freeman *, J. Cerhan *, J. Katzmann*, S. Rajkumar *, M. Alavanja*
MeSH headings : Adult; Age Factors; Aged; Aged, 80 and over; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Blood Protein Electrophoresis; Carbon Disulfide / adverse effects; Carbon Tetrachloride / adverse effects; Cohort Studies; Dieldrin / adverse effects; Electrophoresis, Agar Gel; Humans; Iowa / epidemiology; Male; Middle Aged; Nitriles / adverse effects; North Carolina / epidemiology; Occupational Exposure; Paraproteinemias / chemically induced; Paraproteinemias / epidemiology; Pesticides / adverse effects; Prevalence; Prospective Studies; Sampling Studies
TL;DR:
The prevalence of MGUS among pesticide applicators was twice that in a population-based sample of men from Minnesota, adding support to the hypothesis that specific pesticides are causatively linked to myelomagenesis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2009 journal article
Pesticide use and adult-onset asthma among male farmers in the Agricultural Health Study
European Respiratory Journal, 34(6), 1296–1303.
Contributors: * , D. Umbach *, S. London, P. Henneberger *, G. Kullman*, J. Coble*, M. Alavanja, L. Beane Freeman, D. Sandler
author keywords: Allergy; farming; occupational exposure; pesticides; respiratory disease
MeSH headings : Adult; Aged; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / etiology; Agriculture; Asthma / chemically induced; Asthma / etiology; Carbon Disulfide / toxicity; Carbon Tetrachloride / toxicity; DDT / toxicity; Ethylene Dibromide / toxicity; Humans; Iowa; Male; Middle Aged; North Carolina; Occupational Exposure; Parathion / toxicity; Pesticides / toxicity; Prospective Studies; Smoking; Surveys and Questionnaires
TL;DR:
Pesticide use may be an overlooked contributor to asthma risk among farmers and there was little evidence that allergy alone was driving these associations.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2009 journal article
Pesticides and Myocardial Infarction Incidence and Mortality Among Male Pesticide Applicators in the Agricultural Health Study
American Journal of Epidemiology, 170(7), 892–900.
Contributors: K. Mills *, A. Blair*, L. Freeman, D. Sandler * & *
author keywords: agriculture; cardiovascular diseases; myocardial infarction; occupational exposure; pesticides
MeSH headings : Aged; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / mortality; Follow-Up Studies; Humans; Incidence; Iowa / epidemiology; Male; Middle Aged; Myocardial Infarction / chemically induced; Myocardial Infarction / epidemiology; Myocardial Infarction / mortality; North Carolina / epidemiology; Pesticides / adverse effects; Proportional Hazards Models; Risk
TL;DR:
In a population with low risk for myocardial infarction, the authors observed little evidence of increased risk of myocardioinfarction mortality or nonfatal myocardia infarctions associated with the occupational use of pesticides.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2009 journal article
Rhinitis associated with pesticide exposure among commercial pesticide applicators in the Agricultural Health Study
Occupational and Environmental Medicine, 66(11), 718–724.
Contributors: R. Slager*, J. Poole *, T. LeVan*, D. Sandler *, M. Alavanja* & *
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Benomyl / toxicity; Diazinon / toxicity; Epidemiologic Methods; Glycine / analogs & derivatives; Glycine / toxicity; Humans; Male; Middle Aged; Occupational Exposure / adverse effects; Occupational Exposure / analysis; Oxygenases / toxicity; Pesticides / toxicity; Petroleum / toxicity; Quebec / epidemiology; Rhinitis / chemically induced; Rhinitis / epidemiology; Young Adult
TL;DR:
Exposure to pesticides may increase the risk of rhinitis, based on both current use and exposure–response models, and both petroleum oil and diazinon showed consistent evidence of an association with rhInitis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2009 journal article
Urinary biomarker, dermal, and air measurement results for 2,4-D and chlorpyrifos farm applicators in the Agricultural Health Study
Journal of Exposure Science & Environmental Epidemiology, 20(2), 119–134.
Contributors: K. Thomas *, M. Dosemeci*, * , L. Sheldon*, C. Croghan*, S. Gordon *, M. Jones *, S. Reynolds *
author keywords: 2,4-D; chlorpyrifos; exposure measurement; farm applicator; occupational exposure; Agricultural Health Study
MeSH headings : 2,4-Dichlorophenoxyacetic Acid / analysis; 2,4-Dichlorophenoxyacetic Acid / urine; Biomarkers / urine; Chlorpyrifos / analysis; Chlorpyrifos / urine; Humans; Skin / chemistry
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2009 journal article
Within-person variability in urinary bisphenol A concentrations: Measurements from specimens after long-term frozen storage
Environmental Research, 109(6), 734–737.
Contributors: P. Nepomnaschy *, D. Baird *, C. Weinberg *, * , M. Longnecker * & A. Wilcox *
author keywords: Bisphenol A; Temporal variability; Reproducibility; Menstrual cycle
MeSH headings : Benzhydryl Compounds; Data Interpretation, Statistical; Environmental Pollutants / urine; Female; Freezing; Humans; Menstrual Cycle / physiology; Phenols / urine; Physiological Phenomena; Premenopause / physiology; Specimen Handling / methods; Time Factors; Urinalysis / methods
TL;DR:
The similar distribution to NHANES samples and correlation of BPA levels taken at 2-week intervals provide indirect evidence that BPA is relatively stable during long-term freezer storage and indicate generally stable exposures over periods of weeks.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2009 journal article
Within-person variability in urinary phthalate metabolite concentrations: measurements from specimens after long-term frozen storage
Journal of Exposure Science & Environmental Epidemiology, 20(2), 169–175.
Contributors: D. Baird *, T. Saldana*, P. Nepomnaschy *, * , M. Longnecker *, C. Weinberg *, A. Wilcox *
author keywords: biomarker; phthalate; reproducibility; menstrual cycle; temporal variability
MeSH headings : Cryopreservation; Female; Freezing; Humans; Menstrual Cycle; Phthalic Acids / urine; Reference Standards; Reproducibility of Results
TL;DR:
Results suggest that the measurement of phthalate metabolites after long-term sample storage yield generally similar distributions and temporal reliability as those reported for recently collected specimens, and support the use of stored urine specimens collected during the relevant stage of human pregnancy to investigate the influence ofphthalate exposures on later outcomes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
Agricultural pesticide use and pancreatic cancer risk in the Agricultural Health Study Cohort
International Journal of Cancer, 124(10), 2495–2500.
Contributors: G. Andreotti *, L. Freeman *, L. Hou *, J. Coble*, J. Rusiecki *, * , D. Silverman *, M. Alavanja*
author keywords: pancreatic cancer; pesticides; agriculture
MeSH headings : Aged; Agriculture; Carcinogens / toxicity; Case-Control Studies; Female; Humans; Male; Middle Aged; Occupational Exposure; Pancreatic Neoplasms / chemically induced; Pancreatic Neoplasms / epidemiology; Pesticides / toxicity; Prospective Studies; Registries; Surveys and Questionnaires; United States / epidemiology
TL;DR:
It is suggested that herbicides, particularly pendimethalin and EPTC, may be associated with pancreatic cancer.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
An interlaboratory study of perfluorinated alkyl compound levels in human plasma
Environmental Research, 107(2), 152–159.
Contributors: M. Longnecker *, C. Smith*, G. Kissling*, * , J. Butenhoff*, E. Decker*, D. Ehresman*, M. Ellefson*
author keywords: perfluorinated alkyl compounds; interlaboratory study; persistent organic pollutants; interdisciplinary studies; research design; epidemiologic methods
MeSH headings : Adult; Biomarkers / blood; Environmental Monitoring / standards; Environmental Pollutants / analysis; Female; Fluorocarbons / blood; Humans; Male; Pregnancy
TL;DR:
Considering the degree of between-subject variation in levels among people in background-exposed populations, the results indicate that biomarker-based epidemiologic studies of associations with health could have reasonable precision.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
Aromatic Amine Pesticide Use And Human Cancer Risk: Results From The U.S. Agricultural Health Study
Annals of Epidemiology, 18(9), 720.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 10, 2020
2008 journal article
Cancer Incidence among Pesticide Applicators Exposed to Permethrin in the Agricultural Health Study
Environmental Health Perspectives, 117(4), 581–586.
Contributors: J. Rusiecki *, R. Patel*, S. Koutros *, L. Beane-Freeman *, O. Landgren *, M. Bonner *, J. Coble*, J. Lubin *
author keywords: agriculture; cancer; multiple myeloma; occupation; permethrin; pesticide applicator; pesticides; pyrethroid
MeSH headings : Adult; Female; Humans; Incidence; Insecticides; Iowa / epidemiology; Male; Middle Aged; Neoplasms / epidemiology; North Carolina / epidemiology; Occupational Exposure / statistics & numerical data; Permethrin
TL;DR:
This study found no association with most cancers analyzed, but found elevated and statistically significant risks for multiple myeloma in the highest tertiles of both lifetime exposure-days and intensity-weighted lifetime exposure days.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
Cancer incidence among pesticide applicators exposed to captan in the Agricultural Health Study
Cancer Causes & Control, 19(10), 1401–1407.
Contributors: D. Greenburg*, J. Rusiecki *, S. Koutros *, M. Dosemeci*, R. Patel*, C. Hines*, * , M. Alavanja
author keywords: Captan; Cancer; Agricultural Health Study; Cohort; Prospective; Pesticide; Fungicide; CAS number 133-06-2
MeSH headings : Adult; Agricultural Workers' Diseases / epidemiology; Captan / adverse effects; Cohort Studies; Confidence Intervals; Follow-Up Studies; Fungicides, Industrial / adverse effects; Humans; Incidence; Iowa / epidemiology; Life Style; Male; Middle Aged; Neoplasms / classification; Neoplasms / epidemiology; Neoplasms / etiology; North Carolina / epidemiology; Occupational Exposure / adverse effects; Poisson Distribution; Prevalence; Prospective Studies; Risk Factors; Surveys and Questionnaires; Time Factors
TL;DR:
This study is limited by low numbers of observed cancer cases and follow-up time, it does not provide evidence of an increased risk for the development of cancer at the investigated sites, and no association between the highest tertile of captan exposure and development of all cancers was observed.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
Cancer incidence among pesticide applicators exposed to trifluralin in the Agricultural Health Study
Environmental Research, 107(2), 271–276.
Contributors: D. Kang *, S. Park *, L. Beane-Freeman *, C. Lynch *, C. Knott *, D. Sandler *, * , M. Dosemeci*
author keywords: agriculture; trifluralin; pesticides; cancer; occupational exposure
MeSH headings : Adult; Agriculture; Female; Herbicides / toxicity; Humans; Incidence; Male; Middle Aged; Neoplasms / epidemiology; Neoplasms / etiology; Occupational Exposure; Prospective Studies; Trifluralin / toxicity; United States
TL;DR:
Although there was a possible link between trifluralin exposure and colon cancer, small numbers and inconsistencies in dose-response and subgroup analyses indicate that this may be a chance finding.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
Chlorothalonil exposure and cancer incidence among pesticide applicator participants in the agricultural health study
Environmental Research, 108(3), 400–403.
Contributors: A. Mozzachio*, J. Rusiecki *, * , R. Mahajan*, R. Patel*, L. Beane-Freeman *, M. Alavanja
author keywords: Chlorothalonil; Pesticides; Fungicides; Cancer; Agriculture
MeSH headings : Agriculture / statistics & numerical data; Cohort Studies; Fungicides, Industrial / toxicity; Humans; Neoplasms / chemically induced; Neoplasms / epidemiology; Nitriles / toxicity; North Carolina / epidemiology; Occupational Exposure / analysis; Prospective Studies
TL;DR:
Chlorothalonil was not associated with overall cancer incidence, nor did the authors find any association with colon, lung, and prostate cancers--the only cancers for which they had sufficient numbers to explore associations.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
Depression and Pesticide Exposures among Private Pesticide Applicators Enrolled in the Agricultural Health Study
Environmental Health Perspectives, 116(12), 1713–1719.
Contributors: C. Beseler *, L. Stallones *, * , M. Alavanja, A. Blair*, T. Keefe *, F. Kamel *
author keywords: cumulative exposure; depression; farm applicators; pesticides; pesticide poisoning
MeSH headings : Adult; Agriculture; Depression / chemically induced; Humans; Iowa; Middle Aged; North Carolina; Occupational Exposure; Pesticides / toxicity; Surveys and Questionnaires
TL;DR:
This study is unique in reporting that depression is also associated with chronic pesticide exposure in the absence of a physician-diagnosed poisoning.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
Evaluation of Freeze–Thaw Cycles on Stored Plasma in the Biobank of the Norwegian Mother and Child Cohort Study
Cell Preservation Technology, 6(3), 223–229.
Contributors: L. Paltiel*, K. Rønningen *, H. Meltzer *, S. Baker* & *
TL;DR:
Human plasma can go through several freeze-thaw cycles before analysis without influencing sample integrity for the selected analytes, according to a quality control study using pooled EDTA-plasma.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
Hearing Loss Among Licensed Pesticide Applicators in the Agricultural Health Study
Journal of Occupational and Environmental Medicine, 50(7), 817–826.
Contributors: J. Crawford*, * , M. Alavanja, A. Blair*, D. Sandler * & F. Kamel *
MeSH headings : Adult; Agriculture; Commerce; Health Surveys; Hearing Loss / chemically induced; Hearing Loss / epidemiology; Humans; Licensure; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure; Odds Ratio; Organophosphates; Pesticides / adverse effects
TL;DR:
Although control for exposure to noise or other neurotoxicants was limited, this study extends previous reports suggesting that organophosphate exposure increases risk of hearing loss.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
Heterocyclic aromatic amine pesticide use and human cancer risk: Results from the U.S. Agricultural Health Study
International Journal of Cancer, 124(5), 1206–1212.
Contributors: S. Koutras, C. Lynch *, M. Xiaomei *, J. Won *, * , C. Christensen*, G. Andreotti *, L. Freeman*
author keywords: pesticides; bladder; colon; occupational exposures
MeSH headings : Adult; Aged; Agricultural Workers' Diseases / chemically induced; Colonic Neoplasms / chemically induced; Female; Herbicides / adverse effects; Humans; Male; Middle Aged; Nicotinic Acids / adverse effects; Occupational Exposure / adverse effects; Risk Factors; Urinary Bladder Neoplasms / chemically induced
TL;DR:
Exposure to aromatic amine pesticides may be an overlooked exposure in the etiology of bladder and colon cancer and the use of imazethapyr and other imidazolinone compounds should continue to be evaluated for potential risk to humans.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
Meat and Meat Mutagens and Risk of Prostate Cancer in the Agricultural Health Study
Cancer Epidemiology Biomarkers & Prevention, 17(1), 80–87.
Contributors: S. Koutros *, A. Cross *, D. Sandler *, * , X. Ma *, T. Zheng *, M. Alavanja*, R. Sinha *
MeSH headings : Case-Control Studies; Cohort Studies; Cooking; Diet; Humans; Male; Meat; Middle Aged; Mutagens / adverse effects; Polycyclic Aromatic Hydrocarbons / adverse effects; Prospective Studies; Prostatic Neoplasms / epidemiology; Prostatic Neoplasms / etiology; Quinoxalines / adverse effects
TL;DR:
In conclusion, well and very well done meat was associated with an increased risk for prostate cancer in this cohort.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
Meeting Report: Consensus Statement—Parkinson’s Disease and the Environment: Collaborative on Health and the Environment and Parkinson’s Action Network (CHE PAN) Conference 26–28 June 2007
Environmental Health Perspectives, 117(1), 117–121.
Contributors: J. Bronstein *, P. Carvey*, H. Chen *, D. Cory-Slechta *, D. DiMonte *, J. Duda, P. English *, S. Goldman *
author keywords: cholesterol; coffee; dairy products; diet; dopamine; fatty acids; metals; nonsteroidal anti-inflammatory drugs; Parkinson's disease; pesticides; polychlorinated biphenyls; smoking; statins; urate
MeSH headings : Cooperative Behavior; Environment; Environmental Pollutants / toxicity; Humans; Parkinson Disease / etiology; Research
TL;DR:
A multidisciplinary group of experts gathered in Sunnyvale, California, USA, in June 2007 to assess what is known about the contribution of environmental factors to PD, and came to consensus with respect to environmental contributors to PD risk.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
Occupational Rhinitis is Associated with Pesticide Exposure Among Commercial Pesticide Applicators in the Agricultural Health Study
Journal of Allergy and Clinical Immunology, 121(2), S234–S234.
Sources: Crossref, NC State University Libraries
Added: September 10, 2020
2008 journal article
S -Ethyl- N,N -dipropylthiocarbamate Exposure and Cancer Incidence among Male Pesticide Applicators in the Agricultural Health Study: A Prospective Cohort
Environmental Health Perspectives, 116(11), 1541–1546.
Contributors: D. Bemmel *, K. Visvanathan *, L. Beane Freeman *, J. Coble*, * & M. Alavanja*
author keywords: agriculture; cancer; EPTC; herbicide; neoplasms; occupational exposure; pesticides; thiocarbamates
MeSH headings : Adult; Agricultural Workers' Diseases; Cohort Studies; Herbicides / toxicity; Humans; Incidence; Iowa / epidemiology; Male; Middle Aged; Neoplasms / chemically induced; Neoplasms / epidemiology; North Carolina / epidemiology; Thiocarbamates / toxicity
TL;DR:
In this analysis, EPTC use appeared to be associated with colon cancer and leukemia, however, given the relatively small number of cases in the highest exposure tertile, results should be interpreted with caution, and further investigations are needed.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2007 journal article
Bayesian Methods for Highly Correlated Exposure Data
Epidemiology, 18(2), 199–207.
Contributors: R. MacLehose *, D. Dunson*, A. Herring * & *
MeSH headings : Bayes Theorem; Bias; Confounding Factors, Epidemiologic; Environmental Exposure; Herbicides / adverse effects; Humans; Models, Statistical; Nonlinear Dynamics; Retinal Degeneration / epidemiology; Retinal Degeneration / etiology; Statistics, Nonparametric
TL;DR:
4 hierarchical regression methods are compared and a semiparametric model with a variable-selection prior is presented to allow clustering of coefficients at 0.05 to allow the data to help inform their values.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2007 journal article
Carbaryl exposure and incident cancer in the Agricultural Health Study
International Journal of Cancer, 121(8), 1799–1805.
Contributors: R. Mahajan*, A. Blair*, J. Coble*, C. Lynch *, * , D. Sandler *, M. Alavanja*
author keywords: agriculture; carbamates; carbaryl; insecticides; neoplasms; occupational exposure
MeSH headings : Adult; Aged; Carbaryl / toxicity; Confounding Factors, Epidemiologic; Female; Humans; Incidence; Insecticides / toxicity; Iowa / epidemiology; Lymphoma, Non-Hodgkin / epidemiology; Male; Melanoma / epidemiology; Middle Aged; Neoplasms / chemically induced; Neoplasms / epidemiology; North Carolina / epidemiology; Occupational Diseases / chemically induced; Occupational Diseases / epidemiology; Occupational Exposure / adverse effects; Odds Ratio; Poisson Distribution; Prospective Studies; Prostatic Neoplasms / epidemiology; Skin Neoplasms / epidemiology
TL;DR:
There appeared to be a trend of decreasing prostate cancer risk with increasing level of exposure and a small increase in NHL risk was observed using some, but not all, exposure measures, and associations were observed with other examined cancer sites.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2007 journal article
Chronic Bronchitis Among Nonsmoking Farm Women in the Agricultural Health Study
Journal of Occupational and Environmental Medicine, 49(5), 574–583.
Contributors: M. Valcin*, P. Henneberger *, G. Kullman*, D. Umbach *, S. London *, M. Alavanja, D. Sandler *, *
MeSH headings : Adult; Aged; Agriculture; Bronchitis, Chronic / epidemiology; Bronchitis, Chronic / etiology; Bronchitis, Chronic / physiopathology; Confidence Intervals; Female; Humans; Iowa; Middle Aged; North Carolina; Occupational Exposure; Odds Ratio; Pesticides / adverse effects; Prospective Studies; Surveys and Questionnaires
TL;DR:
Pesticides as well as grain and dust exposures were associated with chronic bronchitis among nonsmoking farm women and off-farm job exposures were organic dusts, asbestos, gasoline, and solvents.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2007 journal article
Dichlorvos exposure and human cancer risk: results from the Agricultural Health Study
Cancer Causes & Control, 19(1), 59–65.
Contributors: S. Koutros *, R. Mahajan, T. Zheng *, * , X. Ma *, C. Lynch *, A. Blair, M. Alavanja
author keywords: pesticides; organophosphate insecticides; dichlorvos (DDVP); prospective cohort; cancer etiology
MeSH headings : Adult; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Agriculture; Dichlorvos / adverse effects; Female; Humans; Insecticides / adverse effects; Male; Middle Aged; Neoplasms / chemically induced; Neoplasms / epidemiology; Occupational Exposure / adverse effects; Risk Factors
TL;DR:
There is little evidence of an association between cumulative lifetime use of DDVP and risk of any cancer at this stage of follow up of the AHS, and DDVP exposure was not associated with any cancer studied here.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2007 journal article
Malathion Exposure and the Incidence of Cancer in the Agricultural Health Study
American Journal of Epidemiology, 166(9), 1023–1034.
Contributors: M. Bonner *, J. Coble*, A. Blair*, L. Beane Freeman *, * , D. Sandler *, M. Alavanja
author keywords: malathion; neoplasms; pesticides
MeSH headings : Adult; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Agriculture; Cohort Studies; Confidence Intervals; Female; Humans; Incidence; Insecticides / adverse effects; International Classification of Diseases; Iowa / epidemiology; Malathion / adverse effects; Male; Middle Aged; Neoplasms / chemically induced; Neoplasms / epidemiology; North Carolina / epidemiology; Occupational Exposure / adverse effects; Odds Ratio; Prospective Studies; Surveys and Questionnaires
TL;DR:
Overall, lifetime days of malathion use was not associated with all cancers combined, and although the rate ratios for melanoma were reduced, small numbers and lack of experimental evidence suggest that the observed reductions may have arisen by chance.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2007 journal article
Mortality among Pesticide Applicators Exposed to Chlorpyrifos in the Agricultural Health Study
Environmental Health Perspectives, 115(4), 528–534.
Contributors: W. Lee *, M. Alavanja*, * , J. Rusiecki *, F. Kamel *, A. Blair*, D. Sandler *
author keywords: chlorpyrifos; farmers; injuries; insecticides; mortality; suicide
MeSH headings : Adult; Aged; Agriculture; Chlorpyrifos / adverse effects; Cohort Studies; Epidemiologic Studies; Female; Humans; Insecticides / adverse effects; Iowa / epidemiology; Male; Middle Aged; Mortality / trends; North Carolina / epidemiology; Occupational Exposure / adverse effects; Prospective Studies; Risk Assessment
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2007 journal article
Neurologic symptoms in licensed pesticide applicators in the Agricultural Health Study
Human & Experimental Toxicology, 26(3), 243–250.
Contributors: F. Kamel *, L. Engel *, B. Gladen, * , M. Alavanja* & D. Sandler *
author keywords: insecticides; neurologic symptoms; organochlorine insecticides; organophosphate insecticides; pesticides; pesticide applicators
MeSH headings : Adolescent; Adult; Aged; Agriculture; Case-Control Studies; Cohort Studies; Humans; Hydrocarbons, Chlorinated / toxicity; Iowa / epidemiology; Male; Middle Aged; Nervous System Diseases / chemically induced; Nervous System Diseases / epidemiology; North Carolina / epidemiology; Occupational Exposure / adverse effects; Organophosphorus Compounds / toxicity; Pesticides / toxicity
TL;DR:
It is suggested that neurologic symptoms are associated with cumulative exposure to moderate levels of organophosphate and organochlorine insecticides, regardless of recent exposure or history of poisoning.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2007 journal article
Pesticide Exposure and Self-Reported Gestational Diabetes Mellitus in the Agricultural Health Study
Diabetes Care, 30(3), 529–534.
Contributors: T. Saldana*, O. Basso *, * , D. Baird *, C. Knott *, A. Blair*, M. Alavanja*, D. Sandler *
MeSH headings : Adolescent; Adult; Agriculture; Body Mass Index; Diabetes, Gestational / epidemiology; Diabetes, Gestational / etiology; Educational Status; Female; Humans; Iowa / epidemiology; Maternal Age; Middle Aged; North Carolina / epidemiology; Parity; Pesticides / toxicity; Pregnancy; Racial Groups; Smoking / epidemiology; Surveys and Questionnaires
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2007 journal article
Pesticide use and chronic bronchitis among farmers in the agricultural health study
American Journal of Industrial Medicine, 50(12), 969–979.
Contributors: * , M. Valcin*, P. Henneberger *, G. Kullman*, D. Limbach, S. London *, M. Alavanja*, D. Sandler *
author keywords: respiratory disease; agricultural exposures; pesticides; occupational exposure
MeSH headings : Adult; Aged; Agriculture; Bronchitis / diagnosis; Bronchitis / epidemiology; Bronchitis / etiology; Chronic Disease; Female; Heptachlor / toxicity; Humans; Male; Middle Aged; North Carolina / epidemiology; Occupational Diseases / diagnosis; Occupational Diseases / epidemiology; Occupational Diseases / etiology; Occupational Exposure / adverse effects; Occupational Health; Pesticides / toxicity; Prospective Studies; Respiratory Tract Diseases / epidemiology; Risk Factors
TL;DR:
Preliminary evidence that pesticide use may increase chronic bronchitis prevalence is provided, using data on lifetime pesticide use and history of doctor-diagnosed chronic Bronchitis from 20,908 private pesticide applicators, primarily farmers.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2007 journal article
Pesticides and Atopic and Nonatopic Asthma among Farm Women in the Agricultural Health Study
American Journal of Respiratory and Critical Care Medicine, 177(1), 11–18.
Contributors: * , D. Umbach *, S. London, P. Henneberger *, G. Kullman*, M. Alavanja*, D. Sandler
author keywords: agricultural workers; allergy; asthma; organophosphates; pesticides
MeSH headings : Adult; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / prevention & control; Asthma / epidemiology; Asthma / prevention & control; Causality; Cohort Studies; Cross-Sectional Studies; Dermatitis, Atopic / epidemiology; Dermatitis, Atopic / prevention & control; Female; Humans; Iowa; Middle Aged; North Carolina; Occupational Exposure / adverse effects; Pesticides / adverse effects; Regression Analysis; Respiratory Hypersensitivity / epidemiology; Respiratory Hypersensitivity / prevention & control; Rhinitis, Allergic, Seasonal / epidemiology; Rhinitis, Allergic, Seasonal / prevention & control; Risk Factors
TL;DR:
It is suggested that pesticides may contribute to atopic asthma, but not nonatopic allergy, among farm women.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2006 journal article
Cancer Incidence among Pesticide Applicators Exposed to Cyanazine in theAgricultural Health Study
Environmental Health Perspectives, 114(8), 1248–1252.
Contributors: S. Lynch *, J. Rusiecki *, A. Blair*, M. Dosemeci*, J. Lubin *, D. Sandler *, * , C. Lynch *, M. Alavanja
author keywords: Agricultural Health Study; cancer; cyanazine; farming; herbicide; pesticides; triazine herbicide
MeSH headings : Adult; Aged; Agricultural Workers' Diseases / epidemiology; Cohort Studies; Colonic Neoplasms / epidemiology; Female; Follow-Up Studies; Hematologic Neoplasms / epidemiology; Herbicides / adverse effects; Humans; Lung Neoplasms / epidemiology; Lymphoma / epidemiology; Male; Middle Aged; Neoplasms / epidemiology; Occupational Exposure / adverse effects; Poisson Distribution; Prospective Studies; Prostatic Neoplasms / epidemiology; Risk Assessment; Triazines / adverse effects
TL;DR:
It was found that there were no clear, consistent associations between cyanazine exposure and any cancer analyzed, and the number of sites was small for certain cancers, limiting any conclusion with regard to ovarian, breast, and some other cancers.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2006 journal article
Cancer Incidence among Pesticide Applicators Exposed to Dicamba in the Agricultural Health Study
Environmental Health Perspectives, 114(10), 1521–1526.
Contributors: C. Samanic*, J. Rusiecki *, M. Dosemeci*, L. Hou *, * , D. Sandler *, J. Lubin *, A. Blair*, M. Alavanja*
author keywords: cancer incidence; farming; neoplasms; pesticides; United States
MeSH headings : Adult; Agricultural Workers' Diseases / epidemiology; Dicamba / toxicity; Humans; Incidence; Middle Aged; Neoplasms / chemically induced; Neoplasms / classification; Neoplasms / epidemiology; North Carolina / epidemiology; Pesticides / toxicity; Registries
TL;DR:
Associations between exposure and lung and colon cancer were observed, but clear evidence for an association between dicamba exposure and cancer risk was not found.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2006 journal article
Cancer incidence among pesticide applicators exposed to metolachlor in the Agricultural Health Study
International Journal of Cancer, 118(12), 3118–3123.
Contributors: J. Rusiecki *, L. Hou *, W. Lee *, A. Blair*, M. Dosemeci*, J. Lubin *, M. Bonner *, C. Samanic*
author keywords: metolachlor; cancer; pesticides; herbicides; applicators
MeSH headings : Acetamides / adverse effects; Adult; Colonic Neoplasms / epidemiology; Colonic Neoplasms / etiology; Female; Follow-Up Studies; Hematologic Neoplasms / epidemiology; Hematologic Neoplasms / etiology; Herbicides / adverse effects; Humans; Incidence; Iowa / epidemiology; Life Style; Lung Neoplasms / epidemiology; Lung Neoplasms / etiology; Male; Middle Aged; Mouth Neoplasms / epidemiology; Mouth Neoplasms / etiology; Neoplasms / epidemiology; Neoplasms / etiology; North Carolina / epidemiology; Occupational Exposure / adverse effects; Pesticides / adverse effects; Poisson Distribution; Prospective Studies; Prostatic Neoplasms / epidemiology; Prostatic Neoplasms / etiology; Registries; Risk Assessment; Risk Factors; Surveys and Questionnaires
TL;DR:
Evaluated the incidence of cancer among pesticide applicators exposed to metolachlor in the Agricultural Health Study, a prospective cohort study of licensed pesticides applicators in Iowa and North Carolina, finding no clear risk for any cancer subtype for exposure to metlachlor.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2006 journal article
Causes of Mortality and Risk Factors for Injury Mortality Among Children in the Agricultural Health Study
Journal of Agromedicine, 11(3-4), 47–59.
Contributors: K. Flower *, * , D. Shore*, C. Lynch *, A. Blair*, C. Knott *, M. Alavanja*, D. Sandler *
TL;DR:
Parent and child characteristics associated with child injury mortality could be used to target farm safety interventions in Iowa and North Carolina between 1975 and 1998.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2006 journal article
Depression and Pesticide Exposures in Female Spouses of Licensed Pesticide Applicators in the Agricultural Health Study Cohort
Journal of Occupational and Environmental Medicine, 48(10), 1005–1013.
MeSH headings : Adult; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / psychology; Agrochemicals / toxicity; Case-Control Studies; Depression / chemically induced; Depression / epidemiology; Environmental Exposure / adverse effects; Female; Health Surveys; Humans; Iowa / epidemiology; Middle Aged; North Carolina / epidemiology; Odds Ratio; Pesticides / toxicity; Risk Factors; Spouses
TL;DR:
Pesticide poisoning may contribute to risk of depression among women who had physician-diagnosed depression requiring medication and lifetime pesticide use was categorized as never mixed/applied pesticides, low exposure, high exposure, and a history of diagnosed pesticide poisoning.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2006 journal article
Farmworker Exposure to Pesticides: Methodologic Issues for the Collection of Comparable Data
Environmental Health Perspectives, 114(6), 923–928.
Contributors: T. Arcury *, S. Quandt *, D. Barr *, * , L. McCauley *, J. Grzywacz *, M. Robson
author keywords: biomonitoring; data collection; environmental assessment; farmworker; health outcomes; pesticide exposure
MeSH headings : Agriculture; Biomarkers; Data Collection / methods; Data Collection / standards; Humans; Occupational Exposure; Pesticides / toxicity
TL;DR:
The Farmworker Pesticide Exposure Comparable Data Conference assembled 25 scientists from diverse disciplinary and organizational backgrounds to develop methodologic consensus in four areas of farmworker pesticide exposure research: environmental exposure assessment, biomarkers, personal and occupational predictors of exposure, and health outcomes of exposure.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2006 journal article
Fertility and exposure to solvents among families in the Agricultural Health Study
Occupational and Environmental Medicine, 63(7), 469–475.
Contributors: M. Sallmén *, D. Baird, * , A. Blair & D. Sandler
MeSH headings : Adult; Agricultural Workers' Diseases / chemically induced; Cross-Sectional Studies; Female; Finland; Humans; Infertility / chemically induced; Male; Middle Aged; Occupational Exposure / adverse effects; Odds Ratio; Regression Analysis; Risk Factors; Solvents / toxicity
TL;DR:
Investigating the impact of solvent exposure on subfertility among families of male licensed pesticide applicators in the Agricultural Health Study cohort found solvents may impair fertility of either gender, though the evidence for female effects is stronger than for male effects.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2006 journal article
Fonofos Exposure and Cancer Incidence in the Agricultural Health Study
Environmental Health Perspectives, 114(12), 1838–1842.
Contributors: R. Mahajan*, A. Blair*, C. Lynch *, P. Schroeder*, * , D. Sandler *, M. Alavanja*
author keywords: agriculture; fonofos; insecticides; neoplasms; occupational exposure; organophosphorus compounds; organothiophosphorus compounds; pesticides
MeSH headings : Adult; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Agriculture; Cohort Studies; Family Health; Female; Fonofos / analysis; Fonofos / poisoning; Humans; Incidence; Iowa / epidemiology; Male; Middle Aged; Neoplasms / chemically induced; Neoplasms / epidemiology; Neoplasms / genetics; North Carolina / epidemiology; Occupational Exposure / adverse effects; Occupational Exposure / analysis; Occupational Exposure / statistics & numerical data; Organophosphate Poisoning; Organophosphorus Compounds / analysis; Organothiophosphorus Compounds / analysis; Organothiophosphorus Compounds / poisoning; Pesticides / analysis; Pesticides / poisoning; Poisson Distribution; Prospective Studies; Prostatic Neoplasms / epidemiology; Prostatic Neoplasms / etiology; Prostatic Neoplasms / genetics; Regression Analysis; Risk Factors; Surveys and Questionnaires
TL;DR:
Although prostate cancer risk was unrelated to fonofos use overall, among applicators with a family history of prostate cancer, the authors observed a significant dose–response trend for lifetime exposure-days, a measure that takes into account factors that modify pesticide exposure.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2006 journal article
Occupational exposure to organochlorine insecticides and cancer incidence in the Agricultural Health Study
International Journal of Cancer, 120(3), 642–649.
Contributors: M. Purdue *, * , A. Blair*, M. Dosemeci* & M. Alavanja*
author keywords: cancer; pesticides; organochlorines; agriculture; cohort study
MeSH headings : Adult; Aged; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / etiology; Aldrin / poisoning; Chlordan / poisoning; Dieldrin / poisoning; Environmental Pollution / adverse effects; Environmental Pollution / analysis; Female; Heptachlor / poisoning; Humans; Hydrocarbons, Chlorinated / poisoning; Incidence; Insecticides / poisoning; Iowa / epidemiology; Male; Middle Aged; Neoplasms / epidemiology; Neoplasms / etiology; North Carolina / epidemiology; Occupational Exposure / adverse effects; Occupational Exposure / analysis; Prospective Studies; Surveys and Questionnaires
TL;DR:
Investigation of the relationship between cancer incidence and OC insecticide use among pesticide applicators enrolled in the Agricultural Health Study found no clear evidence of an association between use of OC insecticides and incident cancers, but some observed associations are supported by previous evidence.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2006 journal article
Pendimethalin Exposure and Cancer Incidence Among Pesticide Applicators
Epidemiology, 17(3), 302–307.
Contributors: L. Hou *, J. Won *, J. Rusiecki *, * , A. Blair*, M. Bonner *, J. Lubin *, C. Samanic*
MeSH headings : Adult; Aniline Compounds / poisoning; Cohort Studies; Environmental Exposure / analysis; Female; Humans; Iowa / epidemiology; Male; Middle Aged; Neoplasms / epidemiology; North Carolina / epidemiology; Prospective Studies; Surveys and Questionnaires
TL;DR:
Overall cancer incidence did not increase with increasing lifetime pendimethalin use, and there was no clear evidence of an association between pendimethelin use and risks for specific cancers, either with overall cancer incidence or with specific cancer sites.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2006 journal article
Pesticide Exposure and Self-reported Parkinson's Disease in the Agricultural Health Study
American Journal of Epidemiology, 165(4), 364–374.
Contributors: F. Kamel *, C. Tanner *, D. Umbach *, * , M. Alavanja*, A. Blair*, K. Comyns*, S. Goldman*
author keywords: case-control studies; herbicides; insecticides; Parkinson disease; pesticides
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agriculture; Child; Environmental Exposure / adverse effects; Female; Follow-Up Studies; Health Surveys; Humans; Incidence; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Parkinson Disease, Secondary / chemically induced; Parkinson Disease, Secondary / epidemiology; Pesticides / adverse effects; Prevalence; Retrospective Studies; Risk Factors
TL;DR:
It is suggested that exposure to certain pesticides may increase PD risk, and findings for specific chemicals may provide fruitful leads for further investigation.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2006 journal article
Pesticide Exposure and Timing of Menopause
American Journal of Epidemiology, 163(8), 731–742.
Contributors: S. Farr *, J. Cai, D. Savitz, D. Sandler, * & G. Cooper
author keywords: agriculture; endocrine disruptors; fertility; hormone antagonists; hormones; menopause; ovary; pesticides
MeSH headings : Adult; Age Factors; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Female; Humans; Interviews as Topic; Iowa / epidemiology; Menstruation Disturbances / chemically induced; Menstruation Disturbances / epidemiology; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Pesticides / toxicity; Proportional Hazards Models; Surveys and Questionnaires
TL;DR:
Pesticide use may be associated with a later age at menopause, and after control for age, smoking status, and past use of oral contraceptives, the median time toMenopause increased by approximately 3 months for women who used pesticides.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2006 journal article
Pesticides and Adult Respiratory Outcomes in the Agricultural Health Study
Annals of the New York Academy of Sciences, 1076(1), 343–354.
Contributors: * , D. Umbach *, S. London *, C. Lynch *, M. Alavanja* & D. Sandler *
author keywords: farmers; occupational exposure; organophosphates; pesticide applicators
MeSH headings : Adult; Agriculture; Animals; Female; Humans; Male; Middle Aged; Pesticides / toxicity; Respiratory Tract Diseases / chemically induced
TL;DR:
The results of the wheeze study are consistent with recent animal models that support a role for organophosphates and respiratory outcomes, and are also consistent with the results of previous studies on grain and animal exposures.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2006 journal article
Pesticides and other agricultural factors associated with self-reported farmer's lung among farm residents in the Agricultural Health Study
Occupational and Environmental Medicine, 64(5), 334–341.
Contributors: * , D. Umbach*, G. Kullman*, P. Henneberger *, S. London *, M. Alavanja, D. Sandler *
MeSH headings : Adult; Agriculture; Agrochemicals / toxicity; Air Pollutants, Occupational / toxicity; Animals; Antigens / adverse effects; Cattle; Cross-Sectional Studies; Environmental Exposure; Farmer's Lung / etiology; Female; Fungi; Health Surveys; Humans; Iowa; Male; Middle Aged; North Carolina; Occupational Exposure / adverse effects; Pesticides / toxicity; Poaceae; Poultry
TL;DR:
While historic farm exposures may contribute to the observed associations with pesticides, these results suggest that organochlorine and carbamate pesticides should be further evaluated as potential risk factors for farmer’s lung.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2006 journal article
Pesticides associated with Wheeze among Commercial Pesticide Applicators in the Agricultural Health Study
American Journal of Epidemiology, 163(12), 1129–1137.
Contributors: * , D. Umbach *, S. London *, C. Lynch *, M. Alavanja & D. Sandler *
author keywords: agriculture; insecticides; occupational exposure; organophosphates; pesticides; signs and symptoms; respiratory; sulfonylurea compounds
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Chi-Square Distribution; Cross-Sectional Studies; Dose-Response Relationship, Drug; Female; Humans; Iowa / epidemiology; Male; Middle Aged; Occupational Exposure / adverse effects; Organophosphorus Compounds / adverse effects; Pesticides / adverse effects; Pyrimidines / adverse effects; Respiratory Sounds; Risk Factors; Sulfonylurea Compounds / adverse effects
TL;DR:
The results add to the emerging literature linking organophosphate insecticides and respiratory health and suggest a role for chlorimuron-ethyl.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2006 journal article
Phorate Exposure and Incidence of Cancer in the Agricultural Health Study
Environmental Health Perspectives, 114(8), 1205–1209.
Contributors: R. Mahajan*, M. Bonner *, * & M. Alavanja
author keywords: agriculture; insecticides; neoplasms; occupational exposure; organophosphorus compounds; organothiophosphorus compounds; pesticides; prostate; phorate
MeSH headings : Adult; Aged; Agricultural Workers' Diseases / epidemiology; Alcohol Drinking / epidemiology; Cohort Studies; Follow-Up Studies; Humans; Insecticides / adverse effects; Insecticides / analysis; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Phorate / adverse effects; Phorate / analysis; Prostatic Neoplasms / epidemiology; Socioeconomic Factors; Surveys and Questionnaires; Zea mays
TL;DR:
The observed statistical interaction suggests a gene–environment interaction between family history and phorate exposure in the incidence of prostate cancer, but other explanations are also possible.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2006 journal article
Reduced Fertility Among Overweight and Obese Men
Epidemiology, 17(5), 520–523.
MeSH headings : Adult; Agriculture / statistics & numerical data; Body Mass Index; Epidemiologic Studies; Humans; Infertility, Male / epidemiology; Infertility, Male / etiology; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Obesity / epidemiology; Odds Ratio; United States / epidemiology
TL;DR:
There was a dose–response relationship, and the BMI effect was stronger when the data were limited to couples with the highest-quality infertility data, suggesting that erectile dysfunction in older men does not explain the association.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2006 journal article
The Biobank in the Norwegian Mother and Child Cohort Study | Biobanken i den norske mor og barn undersøkelsen
Norsk Epidemiologi, 16(1), 59–62. http://www.scopus.com/inward/record.url?eid=2-s2.0-33644958761&partnerID=MN8TOARS
Source: ORCID
Added: September 13, 2019
2006 journal article
The biobank of the Norwegian mother and child cohort Study: A resource for the next 100 years
European Journal of Epidemiology, 21(8), 619–625.
Contributors: K. Rønningen *, L. Paltiel*, H. Meltzer *, R. Nordhagen*, K. Lie*, R. Hovengen*, M. Haugen *, W. Nystad *, P. Magnus *, *
author keywords: automation; biobank; Birth Cohort Study; DNA; plasma; quality control
MeSH headings : Adult; Automation; Biological Specimen Banks / standards; Blood Banks; Child; Child, Preschool; Cohort Studies; Cryopreservation; DNA / isolation & purification; Female; Humans; Infant; Infant, Newborn; Mothers; Norway; Pregnancy; Pregnancy Outcome; Quality Control; Specimen Handling; Temperature; Urine
TL;DR:
With the unique combination of biological specimens and questionnaire data, the MoBa Study will constitute a resource for many future investigations of the separate and combined effects of genetic, environmental factors on pregnancy outcome and on human morbidity, mortality and health in general.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2005 journal article
Cancer Incidence among Male Pesticide Applicators in the Agricultural Health Study Cohort Exposed to Diazinon
American Journal of Epidemiology, 162(11), 1070–1079.
Contributors: L. Freeman *, M. Bonner, A. Blair, * , D. Sandler, J. Lubin, M. Dosemeci, C. Lynch, C. Knott, M. Alavanja
author keywords: cohort studies; diazinon; insecticides; neoplasms; pesticides
MeSH headings : Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Cohort Studies; Comorbidity; Confidence Intervals; Diazinon / toxicity; Humans; Incidence; Insecticides / toxicity; Iowa / epidemiology; Male; Middle Aged; Models, Statistical; Neoplasms / chemically induced; Neoplasms / epidemiology; North Carolina / epidemiology; Occupational Exposure / adverse effects; Occupational Exposure / statistics & numerical data; Prospective Studies; Risk Factors; Smoking / epidemiology
TL;DR:
Results were based on small numbers and additional analyses are necessary as more cases accrue to clarify whether diazinon is associated with cancer risk in humans.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2005 journal article
Cancer incidence in the Agricultural Health Study
Scandinavian Journal of Work, Environment and Health, 31(SUPPL. 1), 39–45. http://www.scopus.com/inward/record.url?eid=2-s2.0-24944553519&partnerID=MN8TOARS
Contributors: M. Alavanja, D. Sandler, C. Lynch, C. Knott, J. Lubin, R. Tarone, K. Thomas, M. Dosemeci
Source: ORCID
Added: September 13, 2019
2005 article
Disease and injury among participants in the Agricultural Health Study
Journal of Agricultural Safety and Health, Vol. 11, pp. 141–150. http://www.scopus.com/inward/record.url?eid=2-s2.0-20444375789&partnerID=MN8TOARS
Source: ORCID
Added: September 13, 2019
2005 journal article
Environmental Exposure Assessment of Pesticides in Farmworker Homes
Environmental Health Perspectives, 114(6), 929–935.
Contributors: * , J. Adgate *, M. Eberhart, M. Nishioka* & P. Ryan *
author keywords: dust sampling; fiarmworkers; pesticides
MeSH headings : Agriculture; Environmental Exposure; Family; Food Analysis; Food Contamination; Humans; Pesticides / toxicity; Population Surveillance; Water Supply / analysis
TL;DR:
This mini-monograph discusses the strategies used to assess pesticide exposures, presents limitations in the available data for farmworkers, and suggests research needs for future studies of pesticide exposure among farmworker families.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2005 journal article
Feasibility of Using Subject-Collected Dust Samples in Epidemiologic and Clinical Studies of Indoor Allergens
Environmental Health Perspectives, 113(6), 665–669.
Contributors: S. Arbes Jr., M. Sever *, B. Vaughn *, J. Mehta*, J. Lynch*, H. Mitchell*, * , H. Spencer*, D. Sandler *, D. Zeldin *
author keywords: allergens; environment; epidemiology; sampling
MeSH headings : Adult; Aged; Allergens / analysis; Antigens, Dermatophagoides / analysis; Arthropod Proteins; Clinical Trials as Topic; Cysteine Endopeptidases; Dust / analysis; Environmental Monitoring / instrumentation; Environmental Monitoring / methods; Epidemiologic Studies; Feasibility Studies; Female; Glycoproteins / analysis; Humans; Male; Middle Aged; Reproducibility of Results
TL;DR:
With some limitations, subject-collected dust sampling appears to be a valid and practical option for epidemiologic and clinical studies that report allergen concentration as a measure of exposure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2005 journal article
Feasibility of using subject-collected dust samples in epidemiological and clinical studies of indoor allergens
Journal of Allergy and Clinical Immunology, 115(2), S97.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 10, 2020
2005 journal article
Glyphosate results revisited (multiple letters) [2]
Environmental Health Perspectives, 113(6). http://www.scopus.com/inward/record.url?eid=2-s2.0-20844449731&partnerID=MN8TOARS
Contributors: D. Farmer, T. Lash, J. Acquavella, A. De Roos, M. Svec, A. Blair, J. Rusiecki, M. Dosemeci
Source: ORCID
Added: September 13, 2019
2005 journal article
Impact of urine preservation methods and duration of storage on measured levels of environmental contaminants
Journal of Exposure Science and Environmental Epidemiology, 16(1), 39–48.
Contributors: * , R. Ulmer*, A. Calafat *, D. Barr *, S. Baker*, H. Meltzer *, K. Rønningen *
Source: ORCID
Added: September 13, 2019
2005 journal article
Impact of urine preservation methods and duration of storage on measured levels of environmental contaminants
Journal of Exposure Science & Environmental Epidemiology, 16(1), 39–48.
author keywords: sample storage and shipment; cohort studies; analytical chemistry; urine
MeSH headings : Environmental Exposure; Environmental Pollutants / urine; Humans; Mass Spectrometry; Reproducibility of Results; Specimen Handling; Temperature; Time Factors; Urinalysis / methods
TL;DR:
In general, most analytes were stable under all conditions with changes in mean concentration over time, temperature, and preservative being generally less than 20%, with the exception of the OP metabolites in the presence of boric acid.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 21, 2021
2005 journal article
Induction of Asthma and the Environment: What We Know and Need to Know
Environmental Health Perspectives, 114(4), 615–619.
Contributors: M. Selgrade*, R. Lemanske Jr., M. Gilmour *, L. Neas *, M. Ward*, P. Henneberger *, D. Weissman *, *
author keywords: air pollution; allergy; asthma economic impact; asthma induction; asthma prevalence; biologics; indoor environment; occupational exposure; public health; susceptibility
MeSH headings : Adolescent; Adult; Asthma / etiology; Asthma / genetics; Child; Child, Preschool; Environmental Exposure; Genetic Predisposition to Disease; Humans; Middle Aged; Needs Assessment; Occupational Diseases / etiology; Public Health; Research
TL;DR:
Seven working groups that focus on ambient air, indoor pollutants (biologics), occupational exposures, early life stages, older adults, intrinsic susceptibility, and lifestyle find strong scientific support for public health efforts to limit in utero and postnatal exposure to cigarette smoke.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2005 journal article
Integrating exposure measurements into epidemiologic studies in agriculture
Scandinavian Journal of Work, Environment and Health, 31(SUPPL. 1), 115–117. http://www.scopus.com/inward/record.url?eid=2-s2.0-24944501381&partnerID=MN8TOARS
Source: ORCID
Added: September 13, 2019
2005 journal article
Neurologic Symptoms in Licensed Private Pesticide Applicators in the Agricultural Health Study
Environmental Health Perspectives, 113(7), 877–882.
Contributors: F. Kamel *, L. Engel *, B. Gladen*, * , M. Alavanja* & D. Sandler *
author keywords: fumigants; insecticides; neurologic symptoms; organochlorines; organophosphates; pesticide applicators; pesticides
MeSH headings : Adolescent; Adult; Aged; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Agrochemicals / adverse effects; Cross-Sectional Studies; Humans; Hydrocarbons, Chlorinated / adverse effects; Iowa / epidemiology; Male; Middle Aged; Nervous System Diseases / chemically induced; Nervous System Diseases / epidemiology; North Carolina / epidemiology; Occupational Exposure; Organophosphorus Compounds / adverse effects; Pesticides / adverse effects
TL;DR:
It is suggested that self-reported neurologic symptoms are associated with cumulative exposure to moderate levels of fumigants and organophosphate and organochlorine insecticides, regardless of recent exposure or history of poisoning.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2005 journal article
Organophosphate pesticide exposure in farmworker family members in western North Carolina and Virginia: Case comparisons
Human Organization, 64(1), 40–51. http://www.scopus.com/inward/record.url?eid=2-s2.0-18544367183&partnerID=MN8TOARS
Source: ORCID
Added: September 13, 2019
2005 journal article
Pesticide Use and Breast Cancer Risk among Farmers' Wives in the Agricultural Health Study
American Journal of Epidemiology, 161(2), 121–135.
Contributors: L. Engel *, D. Hill, , J. Lubin, C. Lynch, J. Pierce, C. Samanic, D. Sandler, A. Blair, M. Alavanja
author keywords: agriculture; agrochemicals; breast neoplasms; fungicides; industrial; herbicides; insecticides; pesticides; risk
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / chemically induced; Breast Neoplasms / chemically induced; Female; Follow-Up Studies; Humans; Iowa; Life Style; Male; Middle Aged; North Carolina; Occupational Exposure / adverse effects; Pesticides / adverse effects; Prospective Studies; Reproductive History; Risk Factors; Spouses
TL;DR:
The authors found no clear association of breast cancer risk with farm size or washing of clothes worn during pesticide application, but risk was modestly elevated among women whose homes were closest to areas of pesticide application.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2005 journal article
Pesticides and neurologic symptoms (multiple letters) [1]
Environmental Health Perspectives, 113(12). http://www.scopus.com/inward/record.url?eid=2-s2.0-29144439284&partnerID=MN8TOARS
Source: ORCID
Added: September 13, 2019
2005 journal article
Retinal Degeneration and Other Eye Disorders in Wives of Farmer Pesticide Applicators Enrolled in the Agricultural Health Study
American Journal of Epidemiology, 161(11), 1020–1029.
Contributors: E. Kirrane *, * , F. Kamel, D. Umbach, W. Boyes, A. DeRoos, M. Alavanja, D. Sandler
author keywords: agriculture; eye diseases; occupational exposure; pesticides; retinal degeneration; spouses
MeSH headings : Adult; Agriculture; Cross-Sectional Studies; Eye Diseases / epidemiology; Eye Diseases / etiology; Female; Humans; Iowa / epidemiology; Middle Aged; North Carolina / epidemiology; Occupational Exposure; Odds Ratio; Pesticides / adverse effects; Regression Analysis; Retinal Degeneration / epidemiology; Retinal Degeneration / etiology; Spouses
TL;DR:
It is suggested that exposure to some fungicides and other pesticides may increase the risk of retinal degeneration and warrant further investigation.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2004 journal article
Association of Pesticide Exposure with Neurologic Dysfunction and Disease
Environmental Health Perspectives, 112(9), 950–958.
Contributors: F. Kamel * & *
author keywords: fumigant; fungicide; insecticide; neurobehavioral performance; neurodegenerative disease; neurologic symptoms; organophosphate; Parkinson disease; pesticide
MeSH headings : Dose-Response Relationship, Drug; Environmental Exposure; Epidemiologic Studies; Genetic Predisposition to Disease; Humans; Nervous System Diseases / etiology; Parkinson Disease / etiology; Pesticides / poisoning; Risk Assessment
TL;DR:
Major unresolved issues include the relative importance of acute and chronic exposure, the effect of moderate exposure in the absence of poisoning, and the relationship of pesticide-related neurotoxicity to neurodegenerative disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Crossref, ORCID
Added: September 13, 2019
2004 journal article
Cancer Incidence Among Pesticide Applicators Exposed to Atrazine in the Agricultural Health Study
JNCI Journal of the National Cancer Institute, 96(18), 1375–1382.
Contributors: J. Rusiecki *, A. De Roos*, W. Lee *, M. Dosemeci*, J. Lubin *, * , A. Blair*, M. Alavanja
MeSH headings : Adult; Aged; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Atrazine / adverse effects; Carcinogens / adverse effects; Confidence Intervals; Female; Herbicides / adverse effects; Humans; Iowa / epidemiology; Male; Middle Aged; Neoplasms / chemically induced; Neoplasms / epidemiology; North Carolina / epidemiology; Odds Ratio; Poisson Distribution; Prospective Studies; Research Design; Surveys and Questionnaires
TL;DR:
The authors' analyses did not find any clear associations between atrazine exposure and any cancer analyzed, however, further studies are warranted for tumor types in which there was a suggestion of trend.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2004 journal article
Cancer Incidence Among Pesticide Applicators Exposed to Chlorpyrifos in the Agricultural Health Study
JNCI Journal of the National Cancer Institute, 96(23), 1781–1789.
Contributors: W. Lee *, A. Blair*, * , J. Lubin *, J. Rusiecki *, D. Sandler *, M. Dosemeci*, M. Alavanja*
MeSH headings : Adult; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Chlorpyrifos / adverse effects; Confidence Intervals; Confounding Factors, Epidemiologic; Humans; Incidence; Insecticides / adverse effects; Iowa / epidemiology; Lung Neoplasms / chemically induced; Lung Neoplasms / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Odds Ratio; Poisson Distribution; Prospective Studies; Research Design; Surveys and Questionnaires
TL;DR:
An association between chlorpyrifos use and incidence of lung cancer that deserves further evaluation is suggested.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2004 journal article
Cancer Incidence among Glyphosate-Exposed Pesticide Applicators in the Agricultural Health Study
Environmental Health Perspectives, 113(1), 49–54.
Contributors: A. De Roos *, A. Blair*, J. Rusiecki *, * , M. Svec*, M. Dosemeci*, D. Sandler *, M. Alavanja*
author keywords: cancer; cohort study; farming; glyphosate; pesticide
MeSH headings : Adult; Aged; Agriculture; Cohort Studies; Female; Glycine / analogs & derivatives; Glycine / poisoning; Herbicides / poisoning; Humans; Incidence; Iowa / epidemiology; Male; Middle Aged; Multiple Myeloma / epidemiology; Multiple Myeloma / etiology; Neoplasms / epidemiology; Neoplasms / etiology; North Carolina / epidemiology; Occupational Exposure; Prospective Studies
TL;DR:
Glyphosate exposure was not associated with cancer incidence overall or with most of the cancer subtypes the authors studied, but there was a suggested association with multiple myeloma incidence that should be followed up as more cases occur in the AHS.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2004 journal article
Cancer Incidence among Pesticide Applicators Exposed to Alachlor in the Agricultural Health Study
American Journal of Epidemiology, 159(4), 373–380.
Contributors: W. Lee *, * , A. Blair, J. Lubin, M. Dosemeci, D. Sandler, M. Alavanja
author keywords: agriculture; cohort studies; herbicides; leukemia; multiple myeloma; neoplasms; occupational exposure; pesticides
MeSH headings : Acetamides; Adult; Agricultural Workers' Diseases / epidemiology; Causality; Cohort Studies; Female; Herbicides; Humans; Incidence; Iowa / epidemiology; Male; Middle Aged; Neoplasms / epidemiology; North Carolina / epidemiology; Occupational Exposure / statistics & numerical data; Prospective Studies; Reference Values
TL;DR:
A possible association between alachlor application and incidence of lymphohematopoietic cancers among applicators in the Agricultural Health Study is suggested.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2004 journal article
Cancer risk and parental pesticide application in children's of agricultural health study participants
Environmental Health Perspectives, 112(5), 631–635. http://www.scopus.com/inward/record.url?eid=2-s2.0-16544378273&partnerID=MN8TOARS
Source: ORCID
Added: September 13, 2019
2004 journal article
Comparing questionnaire-based methods to assess occupational silica exposure
Epidemiology, 15(4), 433–441.
Contributors: C. Parks *, G. Cooper*, L. Nylander-French, * , W. Sanderson * & J. Dement *
MeSH headings : Adult; Air Pollutants, Occupational / analysis; Air Pollutants, Occupational / toxicity; Case-Control Studies; Female; Humans; Interviews as Topic; Lupus Erythematosus, Systemic / chemically induced; Lupus Erythematosus, Systemic / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Occupational Exposure / analysis; Occupations / classification; Registries; Risk Assessment / methods; Silicon Dioxide / analysis; Silicon Dioxide / toxicity; South Carolina / epidemiology; Surveys and Questionnaires; Task Performance and Analysis
TL;DR:
Alternative questionnaire-based methods to assess silica exposure in a recent case-control study of patients with systemic lupus erythematosus and controls highlight the limitations of using standardized code groups to define exposure or to select jobs for industrial hygienist review.
(via Semantic Scholar)
Source: ORCID
Added: September 13, 2019
2004 journal article
Diesel Exhaust, Solvents, and Other Occupational Exposures as Risk Factors for Wheeze among Farmers
American Journal of Respiratory and Critical Care Medicine, 169(12), 1308–1313.
Contributors: * , D. Umbach *, S. London *, M. Alavanja* & D. Sandler *
author keywords: agriculture; diesel exhaust; occupational cohort; respiratory symptoms; solvents
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Asthma / chemically induced; Asthma / epidemiology; Cohort Studies; Cross-Sectional Studies; Female; Humans; Hypersensitivity, Immediate / chemically induced; Hypersensitivity, Immediate / epidemiology; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Respiratory Sounds / etiology; Risk Factors; Solvents / adverse effects; Statistics as Topic; Time Factors; Vehicle Emissions / adverse effects
TL;DR:
Activities involving solvent exposure, including painting and use of solvents for cleaning, were associated with an increased odds of wheeze in a duration-dependent fashion, adding to the growing body of evidence of adverse respiratory effects of diesel exposure on the lung.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2004 journal article
Factor analysis of pesticide use patterns among pesticide applicators in the Agricultural Health Study
Journal of Exposure Science & Environmental Epidemiology, 15(3), 225–233.
Contributors: C. Samanic*, * , J. Lubin *, A. Blair* & M. Alavanja*
author keywords: pesticides; farmers; custom applicators; factor analysis; herbicides; insecticides; fungicides; fumigants; Iowa; North Carolina
MeSH headings : Adult; Age Factors; Agriculture; Cohort Studies; Factor Analysis, Statistical; Female; Humans; Iowa; Life Style; Male; Middle Aged; Occupational Exposure; Pesticides / analysis; Risk Assessment; Spouses
TL;DR:
Heterogeneity in exposure patterns to pesticides did not correlate with lifestyle characteristics such as race, smoking status or education, which may be used to guide etiologic studies of health effects of farmers and other groups exposed to pesticides.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2004 journal article
Health Effects of Chronic Pesticide Exposure: Cancer and Neurotoxicity
Annual Review of Public Health, 25(1), 155–197.
Contributors: M. Alavanja*, * & F. Kamel *
author keywords: pesticides; epidemiology; exposure assessment; chronic disease; adult health
MeSH headings : Environmental Exposure; Humans; Neoplasms / chemically induced; Neoplasms / epidemiology; Neurotoxicity Syndromes / epidemiology; Occupational Exposure; Pesticides / toxicity; Risk
TL;DR:
The routes of pesticide exposures occurring today are described, the epidemiologic studies of pesticide-related carcinogenicity and neurotoxicity in adults are summarized, and links between the animal toxicology data and human health effects are evaluated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2004 journal article
Mortality among Participants in the Agricultural Health Study
Annals of Epidemiology, 15(4), 279–285.
Contributors: A. Blair*, D. Sandler *, R. Tarone *, J. Lubin *, K. Thomas *, * , C. Samanic*, J. Coble*
author keywords: farmers; mortality; pesticides; agriculture; cancer
MeSH headings : Agriculture; Cause of Death; Cohort Studies; Disease / classification; Female; Humans; Iowa / epidemiology; Male; Middle Aged; Neoplasms / classification; Neoplasms / epidemiology; Neoplasms / mortality; North Carolina / epidemiology; Occupational Exposure; Pesticides / poisoning; Spouses
TL;DR:
Several factors may contribute to the low mortality observed in this population, including the healthy worker effect typically seen in cohorts of working populations, a short follow-up interval, and a healthier lifestyle manifested through lower cigarette use and an occupation that has traditionally required high levels of physical activity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2004 journal article
Occupational Exposure to Carbofuran and the Incidence of Cancer in the Agricultural Health Study
Environmental Health Perspectives, 113(3), 285–289.
Contributors: M. Bonner *, W. Lee *, D. Sandler *, * , M. Dosemeci* & M. Alavanja*
author keywords: agriculture; cancer incidence; carbofuran; lung cancer; pesticides
MeSH headings : Adult; Aged; Agriculture; Carbofuran / poisoning; Epidemiologic Studies; Female; Humans; Incidence; Insecticides / poisoning; Iowa / epidemiology; Male; Middle Aged; Neoplasms / epidemiology; Neoplasms / etiology; North Carolina / epidemiology; Occupational Exposure
TL;DR:
Although carbamate pesticides are suspected human carcinogens, these results should be interpreted cautiously because there was no a priori hypothesis specifically linking carbofuran to lung cancer.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2004 journal article
Patterns of pesticide use and their determinants among wives of farmer pesticide applicators in the agricultural health study
Journal of Occupational and Environmental Medicine, 46(8), 856–865.
Contributors: E. Kirrane *, * , D. Umbach *, C. Samanic* & D. Sandler *
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agriculture; Agrochemicals; Female; Humans; Logistic Models; Middle Aged; Occupational Exposure / statistics & numerical data; Occupational Health; Pesticides; Spouses
TL;DR:
Engaging in field work and household hygiene practices that could increase exposure were associated with pesticide use, and associations appeared to strengthen with increasing pesticide use category.
(via Semantic Scholar)
Source: ORCID
Added: September 13, 2019
2004 journal article
Pendimethalin exposure and cancer risk among pesticide applicators: a report from the U.S.-based agricultural health study
Annals of Epidemiology, 14(8), 608.
TL;DR:
The findings suggest a possible association between pendimethalin exposure and incidence of rectum and lung cancers among pesticide applicators in the U.S. Agricultural Health Study.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 10, 2020
2004 journal article
Pesticides and Lung Cancer Risk in the Agricultural Health Study Cohort
American Journal of Epidemiology, 160(9), 876–885.
author keywords: lung neoplasms; pesticides
MeSH headings : Acetamides / poisoning; Aged; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Agrochemicals / poisoning; Aniline Compounds / poisoning; Chlorpyrifos / poisoning; Diazinon / poisoning; Female; Herbicides / poisoning; Humans; Incidence; Iowa / epidemiology; Logistic Models; Lung Neoplasms / chemically induced; Lung Neoplasms / epidemiology; Male; Middle Aged; Multivariate Analysis; North Carolina / epidemiology; Occupational Exposure / adverse effects; Occupational Exposure / analysis; Pesticides / poisoning; Population Surveillance; Prospective Studies; Registries; Risk Assessment; Risk Factors; Smoking / adverse effects; Smoking / epidemiology; Surveys and Questionnaires; Time Factors
TL;DR:
A low cigarette smoking prevalence (0.39, 0.49) was observed overall, and two widely used herbicides and insecticides, metolachlor and pendimethalin, showed some evidence of exposure response for lung cancer.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2004 journal article
Phthalate exposure and pulmonary function
Environmental Health Perspectives, 112(5), 571–574. http://www.scopus.com/inward/record.url?eid=2-s2.0-11844285846&partnerID=MN8TOARS
Source: ORCID
Added: September 13, 2019
2004 journal article
Phthalate exposure and pulmonary function.
Environmental Health Perspectives, 112(5), 571–574.
author keywords: monobutyl phthalate; pulmonary function; urine samples
MeSH headings : Adult; Biomarkers; Environmental Exposure; Female; Humans; Linear Models; Lung / drug effects; Lung / physiology; Male; Middle Aged; Nutrition Surveys; Phthalic Acids / toxicity; Phthalic Acids / urine; Respiratory Function Tests; Sex Factors
TL;DR:
It is suggested that MBP and MEP, but not MEHP, may influence pulmonary function among adult males, and the metabolite of the plasticizer commonly used in medical tubing was not adversely associated with any of the pulmonary function parameters evaluated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: September 3, 2020
2004 journal article
Re: "Cancer incidence among pesticide applicators exposed to alachlor in the agricultural health study" [2] (multiple letters)
American Journal of Epidemiology, 161(1), 101–103.
Contributors: C. Poole*, M. Cullen *, R. Irons*, J. Acquavella *, W. Lee, , A. Blair, J. Lubin
MeSH headings : Acetamides; Adult; Agricultural Workers' Diseases / epidemiology; Causality; Female; Herbicides; Humans; Incidence; Iowa / epidemiology; Male; Middle Aged; Neoplasms / epidemiology; North Carolina / epidemiology; Occupational Exposure / statistics & numerical data; Reference Values
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: ORCID
Added: September 13, 2019
2004 journal article
Reporting pesticide assessment results to farmworker families: development, implementation, and evaluation of a risk communication strategy.
Environmental Health Perspectives, 112(5), 636–642.
Contributors: S. Quandt *, A. Doran*, P. Rao *, * , B. Snively * & T. Arcury *
author keywords: agriculture; children; community; environmental justice; exposure; health communication; house dust; Latino/a
MeSH headings : Adult; Agriculture; Communication; Communication Barriers; Environmental Exposure / analysis; Female; Humans; Language; Male; North Carolina; Pesticides / analysis; Risk Assessment / methods; Virginia
TL;DR:
A risk communication strategy for environmental pesticide samples collected in the homes of Latino/a migrant and seasonal farmworkers in a community-based participatory research project was developed with community input and was based on face-to-face meetings with members of participating households.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 13, 2019
2004 journal article
Seed treatment and its implication for fungicide exposure assessment
Journal of Exposure Science & Environmental Epidemiology, 14(3), 195–203.
Contributors: K. White n & *
author keywords: pesticides; fungicides; seed treatment; exposure assessment; agricultural epidemiology
MeSH headings : Agriculture; Cohort Studies; Epidemiologic Studies; Fungicides, Industrial / adverse effects; Fungicides, Industrial / analysis; Humans; Occupational Exposure; Plants, Edible; Seeds
TL;DR:
The extent of potential exposure via use of treated seed using data from a large cohort of licensed pesticide applicators from Iowa and North Carolina was explored and limited data suggest that exposure during planting may be approximately 4% of actively applying fungicide.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018
2003 journal article
Agricultural and residential pesticides in wipe samples from farmworker family residences in North Carolina and Virginia.
Environmental Health Perspectives, 112(3), 382–387.
Contributors: S. Quandt *, T. Arcury *, P. Rao *, B. Snively *, D. Camman, A. Doran*, A. Yau *, * , D. Jackson *
author keywords: agriculture; children; exposure; house dust; Latino
MeSH headings : Adult; Agriculture; Child; Child Welfare; Environmental Exposure; Environmental Monitoring; Family; Female; Housing; Humans; Male; North Carolina; Occupational Exposure; Pesticides / analysis; Virginia
Sources: Crossref, ORCID
Added: September 13, 2019
2003 journal article
Animal production and wheeze in the Agricultural Health Study: interactions with atopy, asthma, and smoking
Occupational and Environmental Medicine, 60(8), 3e–3.
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / etiology; Animal Husbandry; Animals; Asthma / etiology; Cross-Sectional Studies; Female; Humans; Iowa / epidemiology; Logistic Models; Male; Middle Aged; Respiratory Hypersensitivity / etiology; Respiratory Sounds; Risk Factors; Smoking / adverse effects
TL;DR:
Results are consistent with animal production and respiratory symptoms, and suggest that subgroups may respond differently to exposure, including atopics, asthmatics and smokers.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: September 3, 2020
2003 journal article
Animal production and wheeze in the Agricultural Health Study: interactions with atopy, asthma, and smoking.
Occupational and Environmental Medicine, 60(8). http://www.scopus.com/inward/record.url?eid=2-s2.0-0141454811&partnerID=MN8TOARS
Source: ORCID
Added: September 13, 2019
2003 journal article
Cancer risk and parental pesticide application in children of Agricultural Health Study participants.
Environmental Health Perspectives, 112(5), 631–635.
author keywords: agricultural workers; cancer; children; occupational exposure; pesticides
MeSH headings : Adolescent; Adult; Agriculture; Child; Child, Preschool; Female; Humans; Incidence; Infant; Iowa; Lymphoma / chemically induced; Lymphoma / epidemiology; Male; Maternal Exposure / adverse effects; Neoplasms / chemically induced; Neoplasms / epidemiology; Paternal Exposure / adverse effects; Pesticides / toxicity; Prospective Studies; Retrospective Studies; Risk
TL;DR:
Analysis of childhood cancer risk and associations with parental pesticide application in Iowa suggests that farm exposures including pesticides may play a role in the etiology of childhood lymphoma.
(via Semantic Scholar)
Source: Crossref
Added: September 3, 2020
2003 journal article
Male reproductive effects of phthalates: An emerging picture
Epidemiology, 14(3), 259–260.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: September 13, 2019
2003 journal article
Use of Agricultural Pesticides and Prostate Cancer Risk in the Agricultural Health Study Cohort
American Journal of Epidemiology, 157(9), 800–814.
Contributors: M. Alavanja*, C. Samanic, M. Dosemeci, J. Lubin, R. Tarone, C. Lynch, C. Knott, K. Thomas
author keywords: agrochemicals; fungicides, industrial; herbicides; insecticides; pesticides; prostatic neoplasms; risk
MeSH headings : Adult; Age Distribution; Aged; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / etiology; Cohort Studies; Humans; Incidence; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Odds Ratio; Pesticides / adverse effects; Pesticides / classification; Prostatic Neoplasms / chemically induced; Prostatic Neoplasms / epidemiology; Prostatic Neoplasms / etiology; Surveys and Questionnaires
TL;DR:
Use of chlorinated pesticides among applicators over 50 years of age and methyl bromide use were significantly associated with prostate cancer risk, and several other pesticides showed a significantly increased risk of prostate cancer among study subjects with a family history of prostatecancer but not among those with no family history.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2002 journal article
A Quantitative Approach for Estimating Exposure to Pesticides in the Agricultural Health Study
The Annals of Occupational Hygiene, 46(2), 245–260.
author keywords: exposure assessment; pesticide exposure; agricultural exposures; farmers; pesticide applicators; occupational exposures
MeSH headings : Accidents, Occupational; Agriculture; Algorithms; Humans; Iowa; North Carolina; Occupational Exposure; Pesticides / poisoning; Prospective Studies; Protective Clothing; Risk Assessment / methods; Surveys and Questionnaires
TL;DR:
A quantitative method to estimate long-term chemical-specific pesticide exposures in a large prospective cohort study of more than 58000 pesticide applicators in North Carolina and Iowa found that the take-home questionnaire sub-cohort of applicators is representative of the entire cohort in terms of exposure.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2002 journal article
Accuracy of self-reported pesticide use duration information from licensed pesticide applicators in the Agricultural Health Study
Journal of Exposure Science & Environmental Epidemiology, 12(5), 313–318.
Contributors: * , F. Yucel*, M. Dosemeci* & D. Sandler *
author keywords: accuracy; farmers; pesticides; pesticide registration; questionnaire
MeSH headings : Epidemiologic Studies; Humans; Mental Recall; Occupational Exposure; Pesticides / chemistry; Pesticides / classification; Quality Control; Reproducibility of Results; Retrospective Studies; Time Factors
TL;DR:
The quality of the self-reported pesticide product use history of 57,311 licensed pesticide applicators in the Agricultural Health Study is compared to the year the pesticide active ingredient was first registered for use to suggest participants provide plausible information regarding their pesticide use.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2002 journal article
Chemical Predictors of Wheeze among Farmer Pesticide Applicators in the Agricultural Health Study
American Journal of Respiratory and Critical Care Medicine, 165(5), 683–689.
Contributors: * , D. Umbach *, S. London *, M. Alavanja & D. Sandler *
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Asthma / chemically induced; Asthma / epidemiology; Causality; Cohort Studies; Female; Humans; Iowa; Male; Middle Aged; North Carolina; Pesticides / adverse effects; Respiratory Sounds / etiology; Risk Factors
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, ORCID
Added: September 13, 2019
2002 journal article
Occupational exposure to crystalline silica and risk of systemic lupus erythematosus: A population-based, case-control study in the Southeastern United States
Arthritis & Rheumatism, 46(7), 1840–1850.
Contributors: C. Parks *, G. Cooper*, L. Nylander-French *, W. Sanderson *, J. Dement *, P. Cohen *, M. Dooley*, E. Treadwell *
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Educational Status; Female; Humans; Logistic Models; Lupus Erythematosus, Systemic / chemically induced; Lupus Erythematosus, Systemic / epidemiology; Male; Middle Aged; Occupational Exposure; Prevalence; Racial Groups; Silicon Dioxide / adverse effects; Southeastern United States / epidemiology
TL;DR:
It is suggested that crystalline silica exposure may promote the development of SLE in some individuals and additional research is recommended in other populations.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2002 journal article
Potential for selection bias with tumor tissue retrieval in molecular epidemiology studies
Annals of Epidemiology, 12(1), 1–6.
author keywords: molecular epidemiology; selection bias; tumor tissue
MeSH headings : Aged; California / epidemiology; Female; Humans; Male; Middle Aged; Molecular Epidemiology; Pancreatic Neoplasms / diagnosis; Pancreatic Neoplasms / epidemiology; Pancreatic Neoplasms / pathology; SEER Program; Selection Bias
TL;DR:
The potential for bias associated with differential availability of tumor blocks is discussed including consideration of tumor, patient, and hospital characteristics and the determinants of selection are described in all studies using tumor tissue.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: September 13, 2019
2002 journal article
Prevalence of exposure to solvents, metals, grain dust, and other hazards among farmers in the Agricultural Health Study
Journal of Exposure Science & Environmental Epidemiology, 12(6), 418–426.
Contributors: J. Coble*, * , L. Engel *, O. Elci *, M. Dosemeci*, C. Lynch *, M. Alavanja
author keywords: confounding; exposure; farmers; pesticides
MeSH headings : Agriculture; Confounding Factors, Epidemiologic; Dust; Epidemiologic Studies; Female; Humans; Iowa / epidemiology; Male; Metals, Heavy / adverse effects; Metals, Heavy / analysis; Middle Aged; North Carolina / epidemiology; Occupational Exposure; Occupational Health; Pesticides / adverse effects; Pesticides / analysis; Prevalence; Risk Assessment; Solvents / adverse effects; Solvents / analysis
TL;DR:
The associations between the use of pesticides and the frequency with which the farmers in the AHS reported performing various types of specific farming activities were assessed to evaluate potential confounding, suggesting the magnitude of bias due to confounding is likely to be minimal.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2002 journal article
Reproducibility of urinary phthalate metabolites in first morning urine samples.
Environmental Health Perspectives, 110(5), 515–518.
Contributors: * , J. Brock *, B. Davis* & D. Baird *
author keywords: biologic markers; environmental exposure; phthalates; reliability; urine; women's health
MeSH headings : Adult; Biomarkers / analysis; Chromatography, High Pressure Liquid; Environmental Exposure; Female; Half-Life; Humans; Middle Aged; Phthalic Acids / urine; Reproducibility of Results; Sensitivity and Specificity; Specimen Handling; Urinalysis
TL;DR:
The results suggest that even with the short half-lives of phthalates, women's patterns of exposure may be sufficiently stable to assign an exposure level based on a single first morning void urine measurement.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 13, 2019
2001 journal article
AGRICULTURAL EXPOSURE HISTORY AMONG AFRICAN-AMERICAN FARMERS IN GEORGIA
Journal of Toxicology and Environmental Health, Part A, 63(4), 237–241.
MeSH headings : Adult; Black or African American; Aged; Aged, 80 and over; Agricultural Workers' Diseases / epidemiology; Data Collection; Georgia / epidemiology; Humans; Male; Middle Aged; Occupational Exposure / statistics & numerical data; Pesticides; Surveys and Questionnaires
TL;DR:
A pilot study was conducted to explore the breadth and diversity of farming practices over time among African-American farmers in Georgia whose exposures may differ in important ways.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2000 journal article
K-ras and p53 in pancreatic cancer: Association with medical history, histopathology, and environmental exposures in a population-based study
Cancer Epidemiology Biomarkers and Prevention, 9(11), 1223–1232. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033729483&partnerID=MN8TOARS
Source: ORCID
Added: September 13, 2019
2000 journal article
Letters to the Editor: The validity of self-reported prostrate cancer screening history
Preventive Medicine, 30(1), 78.
MeSH headings : Adult; Aged; Aged, 80 and over; Focus Groups; Humans; Male; Mass Screening / methods; Middle Aged; Prostatic Neoplasms / diagnosis; Prostatic Neoplasms / prevention & control; Reproducibility of Results; Surveys and Questionnaires
UN Sustainable Development Goal Categories
4. Quality Education
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2000 journal article
Measurement variability associated with KXRF bone lead measurement in young adults
Environmental Health Perspectives, 108(3), 239–242. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034128551&partnerID=MN8TOARS
Source: ORCID
Added: September 13, 2019
2000 journal article
Measurement variability associated with KXRF bone lead measurement in young adults.
Environmental Health Perspectives, 108(3), 239–242.
MeSH headings : Adolescent; Adult; Age Factors; Analysis of Variance; Bias; Body Burden; Bone Density; Boston; Cadaver; Environmental Exposure / analysis; Environmental Monitoring / methods; Female; Humans; Lead / analysis; Male; Radiography; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, X-Ray Emission / instrumentation; Spectrometry, X-Ray Emission / methods; Tibia / chemistry; Tibia / diagnostic imaging
TL;DR:
The degree of variability that may be associated with bone lead measurements of young subjects with low bone lead concentrations using a standard spot-source KXRF instrument is described.
(via Semantic Scholar)
Source: Crossref
Added: September 3, 2020
2000 journal article
Occupational exposure to chlorophenol and the risk of nasal and nasopharyngeal cancers among U.S. Men aged 30 to 60
American Journal of Industrial Medicine, 37(5), 532–541.
Contributors: M. Mirabelli *, * , P. Tolbert*, R. Herrick, D. Gnepp* & E. Brann*
author keywords: occupational exposure; chlorophenols; nasal cancer; nasopharyngeal cancer
TL;DR:
The hypothesis that occupational exposure to chlorophenol is a risk factor for nasal and nasopharyngeal cancer is supported, although the role of machining-related exposures warrants further assessment.
(via Semantic Scholar)
Source: ORCID
Added: September 13, 2019
2000 journal article
Pancreatic cancer and serum organochlorine levels
Cancer Epidemiology Biomarkers and Prevention, 9(2), 199–205. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034003536&partnerID=MN8TOARS
Source: ORCID
Added: September 13, 2019
1999 journal article
Occupational chlorophenol exposure and non-Hodgkin's lymphoma
Journal of Occupational and Environmental Medicine, 41(4), 267–272. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032943982&partnerID=MN8TOARS
Source: ORCID
Added: September 13, 2019
1999 journal article
Occupational risk factors for sarcoma subtypes
Epidemiology, 10(3), 300–306. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032928122&partnerID=MN8TOARS
Source: ORCID
Added: September 13, 2019
1999 journal article
Patterns of genetic alterations in pancreatic cancer: A pooled analysis
Environmental and Molecular Mutagenesis, 33(2), 111–122.
Contributors: H. Blanck *, P. Tolbert* & *
author keywords: pancreatic cancer; p53; K-ras; gene mutations; epidemiology
TL;DR:
A pooled analysis of the published data on genetic mutations associated with pancreatic ductal adenocarcinoma found the mutational pattern of p53 in pancreatic cancer is similar to bladder cancer, another smoking‐related cancer, but not to lung cancer.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: September 13, 2019
1998 journal article
Occupational Chlorophenol Exposure and Soft Tissue Sarcoma Risk among Men Aged 30-60 Years
American Journal of Epidemiology, 148(7), 693–703.
Contributors: * , P. Tolbert*, R. Herrick*, D. Freedman *, B. Ragsdale*, K. Horvat*, E. Brann*
author keywords: chlorophenols; occupational exposure; oils; sarcoma; soft tissue
MeSH headings : Adult; Case-Control Studies; Chlorophenols / adverse effects; Herbicides / adverse effects; Humans; Male; Middle Aged; Occupational Exposure; Prevalence; Risk Factors; Sarcoma / epidemiology; Sarcoma / etiology; Soft Tissue Neoplasms / epidemiology; Soft Tissue Neoplasms / etiology
TL;DR:
Chlorophenol exposure independent of phenoxyherbicides may increase the risk of soft tissue sarcoma because of the large number of machinists in the exposed group and the complex composition of cutting fluids.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 13, 2019
1998 journal article
Use of a life events calendar approach to elicit occupational history from farmers
American Journal of Industrial Medicine, 34(5), 470–476.
author keywords: epidemiology; exposure assessment; farming; questionnaires; survey methods
TL;DR:
The life events calendar provided a useful tool to facilitate the recall of a lifetime of agricultural activity and are useful additions to the tools available for retrospective occupational exposure assessment.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: ORCID
Added: September 13, 2019
1997 journal article
In Vivo Bone Lead Measurement in Suburban Teenagers
PEDIATRICS, 100(3), 365–370.
Contributors: * , A. Aro*, H. Hu * & P. Ryan*
author keywords: lead; bone; environmental health; adolescents; environmental exposure; epidemiology
MeSH headings : Adolescent; Adult; Age Factors; Asian People; Black People; Bone and Bones / chemistry; Boston; Cross-Sectional Studies; Demography; Environmental Exposure; Environmental Pollutants / analysis; Female; Forecasting; Housing; Humans; Lead / analysis; Lead / blood; Lead Poisoning / metabolism; Male; Minerals / analysis; Minority Groups; Sex Factors; Spectrometry, X-Ray Emission; Suburban Health; Surveys and Questionnaires; Tibia / chemistry; White People
TL;DR:
The results demonstrate that although bone lead levels are measurable in this age group, the common predictors of blood and bone lead concentrations are not explanatory for bone lead Levels.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
1997 journal article
Validation of a Self-Administered Lead Exposure Questionnaire among Suburban Teenagers
Environmental Research, 74(1), 1–10.
MeSH headings : Adolescent; Boston / epidemiology; Environmental Exposure; Humans; Lead Poisoning / epidemiology; Residence Characteristics; Suburban Population; Surveys and Questionnaires
TL;DR:
The results illustrate that questionnaires continue to be useful in evaluating home lead levels even in suburban homes and that teenagers are accurate respondents.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
1996 journal article
Bone lead levels and delinquent behavior
JAMA: The Journal of the American Medical Association, 275(22), 1727b–1727.
MeSH headings : Bone and Bones / chemistry; Child; Child Behavior Disorders; Humans; Lead / analysis; Social Behavior Disorders; Spectrometry, X-Ray Emission
Source: Crossref
Added: September 3, 2020
1996 journal article
Bone lead levels and delinquent behavior [3]
Journal of the American Medical Association, 275(22), 1725–1728.
Source: ORCID
Added: September 13, 2019
1996 journal article
Bone lead levels and delinquent behavior.
JAMA : the Journal of the American Medical Association, 275(22). http://www.scopus.com/inward/record.url?eid=2-s2.0-0030580911&partnerID=MN8TOARS
Source: ORCID
Added: September 13, 2019
1995 journal article
Airway obstruction in boilermakers exposed to fuel oil ash. A prospective investigation.
American Journal of Respiratory and Critical Care Medicine, 152(5), 1478–1484.
MeSH headings : Adult; Air Pollutants, Occupational / adverse effects; Air Pollutants, Occupational / analysis; Airway Obstruction / chemically induced; Airway Obstruction / diagnosis; Bronchial Provocation Tests / statistics & numerical data; Engineering / statistics & numerical data; Fuel Oils / adverse effects; Humans; Linear Models; Male; Methacholine Chloride; Middle Aged; Occupational Diseases / chemically induced; Occupational Diseases / diagnosis; Prospective Studies; Spirometry / statistics & numerical data; Statistics, Nonparametric; Surveys and Questionnaires; Vanadium Compounds / adverse effects; Vanadium Compounds / analysis
TL;DR:
A significant fall inFEV1 and a dose-response relationship between delta FEV1.adj and average and peak PM10 exposure and respirable vanadium dust concentration is found and there was no postexposure change in nonspecific airway responsiveness.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: September 3, 2020
1995 journal article
Airway obstruction in boilermakers exposed to fuel oil ash: A prospective investigation
American Journal of Respiratory and Critical Care Medicine, 152(5 I), 1478–1484. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028806709&partnerID=MN8TOARS
Source: ORCID
Added: September 13, 2019
1995 journal article
Upper airway response in workers exposed to fuel oil ash: nasal lavage analysis.
Occupational and Environmental Medicine, 52(5), 353–358.
author keywords: NASAL LAVAGE; FUEL OIL ASH; VANADIUM
MeSH headings : Adult; Dust / adverse effects; Fuel Oils; Humans; Leukocyte Count / drug effects; Male; Middle Aged; Nasal Lavage Fluid; Neutrophils / drug effects; Occupational Diseases / chemically induced; Rhinitis / chemically induced; Smoking / pathology; Therapeutic Irrigation; Vanadium Compounds / administration & dosage; Vanadium Compounds / adverse effects
TL;DR:
In non-smokers, exposure to fuel oil ash is associated with upper airway inflammation manifested as increased polymorphonuclear cell counts, which suggests that smoking masks the effect of exposure tofuel oil ash.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, ORCID
Added: September 13, 2019
1995 journal article
Validation of K-XRF bone lead measurement in young adults.
Environmental Health Perspectives, 103(1), 78–83.
MeSH headings : Adolescent; Adult; Bone and Bones / chemistry; Environmental Exposure; Feasibility Studies; Female; Humans; Lead / analysis; Male; Pilot Projects; Reproducibility of Results; Spectrometry, X-Ray Emission
TL;DR:
K-XRF may not yet be a useful diagnostic tool for individual subjects, but it may be of great use to environmental scientists trying to characterize long-term lead exposure and dose in the general population or specific subpopulations.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 13, 2019
Employment
Updated: May 17th, 2021 21:13
2019 - present
North Carolina State University Raleigh, NC, US
Professor
Biological Sciences
2013 - 2019
North Carolina State University Raleigh, NC, US
Associate Professor
Department of Biological Sciences
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