Jorge Piedrahita Hill, A. B. T., Murphy, Y. M., Polkoff, K. M., Edwards, L., Walker, D. M., Moatti, A., … Piedrahita, J. A. (2024). [Review of A gene edited pig model for studying LGR5+ stem cells: implications for future applications in tissue regeneration and biomedical research]. FRONTIERS IN GENOME EDITING, 6. https://doi.org/10.3389/fgeed.2024.1401163 Schaaf, C. R., Polkoff, K. M., Carter, A., Stewart, A. S., Sheahan, B., Freund, J., … Gonzalez, L. M. (2023). A LGR5 reporter pig model closely resembles human intestine for improved study of stem cells in disease. FASEB JOURNAL, 37(6). https://doi.org/10.1096/fj.202300223R Zhang, W., Wang, X., Lanzoni, G., Wauthier, E., Simpson, S., Ezzell, J. A., … Reid, L. M. A. (2023). A postnatal network of co-hepato/pancreatic stem/progenitors in the biliary trees of pigs and humans. NPJ REGENERATIVE MEDICINE, 8(1). https://doi.org/10.1038/s41536-023-00303-5 Liu, B., Paudel, S., Flowers, W. L., Piedrahita, J. A., & Wang, X. (2023, May). 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Biomechanical Function and Size of the Anteromedial and Posterolateral Bundles of the ACL Change Differently with Skeletal Growth in the Pig Model. CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 477(9), 2161–2174. https://doi.org/10.1097/CORR.0000000000000884 Cone, S. G., Piedrahita, J. A., Spang, J. T., & Fisher, M. B. (2019). In Situ Joint Stiffness Increases During Skeletal Growth but Decreases Following Partial and Complete Anterior Cruciate Ligament Injury. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 141(12). https://doi.org/10.1115/1.4044582 Cone, S. G., Piercy, H. E., Lambeth, E. P., Ru, H., Piedrahita, J. A., Spang, J. T., … Fisher, M. B. (2019). Tissue-specific changes in size and shape of the ligaments and tendons of the porcine knee during post-natal growth. PLOS ONE, 14(10). https://doi.org/10.1371/journal.pone.0219637 Gupta, N., Polkoff, K., Qiao, L., Cheng, K., & Piedrahita, J. (2019). 200 Developing exosomes as a mediator for CRISPR/Cas-9 delivery. Reproduction, Fertility and Development, 31(1), 225. https://doi.org/10.1071/RDV31N1AB200 Chung, J., Zhang, X., Collins, B., Sper, R. B., Gleason, K., Simpson, S., … Piedrahita, J. A. (2018). High mobility group A2 (HMGA2) deficiency in pigs leads to dwarfism, abnormal fetal resource allocation, and cryptorchidism. Proceedings of the National Academy of Sciences, 115(21), 5420–5425. https://doi.org/10.1073/pnas.1721630115 Jungersen, G., & Piedrahita, J. (2018). INTRODUCTION: Immune Relevant Animal Models: Opportunities and Challenges. ILAR JOURNAL, Vol. 59, pp. 209–210. https://doi.org/10.1093/ilar/ilz014 Platt, J. L., Cascalho, M., & Piedrahita, J. A. (2018). [Review of Xenotransplantation: Progress Along Paths Uncertain from Models to Application]. ILAR JOURNAL, 59(3), 286–308. https://doi.org/10.1093/ilar/ily015 Piedrahita, J. A., & Williams, J. K. (2017). Animal Models in Tissue Engineering. Part I. 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Improved Chondrogenic Potential and Proteomic Phenotype of Porcine Chondrocytes Grown in Optimized Culture Conditions. Cellular Reprogramming, 19(4), 232–244. https://doi.org/10.1089/cell.2017.0005 Cone, S. G., Simpson, S. G., Piedrahita, J. A., Fordham, L. A., Spang, J. T., & Fisher, M. B. (2017). Orientation changes in the cruciate ligaments of the knee during skeletal growth: A porcine model. Journal of Orthopaedic Research, 35(12), 2725–2732. https://doi.org/10.1002/jor.23594 Jeong, K. Y., Nelson, P. V., Niedziela, C. E., Jr., & Dickey, D. A. (2016). Effect of Plant Species, Fertilizer Acidity/Basicity, and Fertilizer Concentration on pH of Soilless Root Substrate. HORTSCIENCE, 51(12), 1596–1601. https://doi.org/10.21273/hortsci11237-16 Sper, R., Simpson, S., Zhang, X., Collins, B., & Piedrahita, J. (2016). 1 GENERATION OF A STABLE TRANSGENIC SWINE MODEL FOR CELL TRACKING AND CHROMOSOME DYNAMIC STUDIES. 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Generation of Induced Pluripotent Stem Cells (iPSCs) from Adult Canine Fibroblasts. In Methods in Molecular Biology (pp. 69–78). https://doi.org/10.1007/978-1-4939-2848-4_7 Vandergriff, A. C., de Andrade, J. B. M., Tang, J., Hensley, M. T., Piedrahita, J. A., Caranasos, T. G., & Cheng, K. (2015). Intravenous Cardiac Stem Cell-Derived Exosomes Ameliorate Cardiac Dysfunction in Doxorubicin Induced Dilated Cardiomyopathy. Stem Cells International, 2015, 1–8. https://doi.org/10.1155/2015/960926 Gonçalves, N. N., Ambrósio, C. E., & Piedrahita, J. A. (2014). Stem Cells and Regenerative Medicine in Domestic and Companion Animals: A Multispecies Perspective. Reproduction in Domestic Animals, 49, 2–10. https://doi.org/10.1111/rda.12392 Chung, J., Zhang, X., Colins, B., Howard, K., Simpson, S., Salmon, C., … Piedrahita, J. (2014). 5 DISRUPTION OF THE HIGH MOBILITY GROUP AT-HOOK 2 (HMGA2) GENE IN SWINE REDUCES POSTNATAL GROWTH. Reproduction, Fertility and Development, 26(1), 117. https://doi.org/10.1071/RDV26N1AB5 Lim, J.-H., McCullen, S. D., Piedrahita, J. A., Loboa, E. G., & Olby, N. J. (2013). Alternating Current Electric Fields of Varying Frequencies: Effects on Proliferation and Differentiation of Porcine Neural Progenitor Cells. Cellular Reprogramming, 15(5), 405–412. https://doi.org/10.1089/cell.2013.0001 Gonzalez, L. M., Williamson, I., Piedrahita, J. A., Blikslager, A. T., & Magness, S. T. (2013). Cell lineage identification and stem cell culture in a porcine model for the study of intestinal epithelial regeneration. PLoS One, 8(6). Bischoff, S. R., Tsai, S. Q., Hardison, N. E., Motsinger-Reif, A. A., Freking, B. A., Nonneman, D. J., … Piedrahita, J. A. (2013). Differences in X-Chromosome Transcriptional Activity and Cholesterol Metabolism between Placentae from Swine Breeds from Asian and Western Origins. PLOS ONE, 8(1). https://doi.org/10.1371/journal.pone.0055345 Guo, L., Tsai, S. Q., Hardison, N. E., James, A. H., Motsinger-Reif, A. A., Thames, B., … Piedrahita, J. A. (2013). Differentially expressed microRNAs and affected biological pathways revealed by modulated modularity clustering (MMC) analysis of human preeclamptic and IUGR placentas. Placenta, 34(7), 599–605. https://doi.org/10.1016/j.placenta.2013.04.007 Farmer, W. T., Farin, P. W., Piedrahita, J. A., Bischoff, S. R., & Farin, C. E. (2013). Expression of antisense of insulin-like growth factor-2 receptor RNA non-coding (AIRN) during early gestation in cattle. Animal Reproduction Science, 138(1-2), 64–73. https://doi.org/10.1016/J.ANIREPROSCI.2013.01.009 Koh, S., & Piedrahita, J. A. (2014). [Review of From "ES-like" cells to induced pluripotent stem cells: A historical perspective in domestic animals]. THERIOGENOLOGY, 81(1), 103–111. https://doi.org/10.1016/j.theriogenology.2013.09.009 Gonzalez, L., Blikslager, A., Piedrahita, J. A., & Magness, S. T. (2013). Su1099 A Translational Porcine Model of Intestinal Stem Cells. Gastroenterology, 144(5), S-398. https://doi.org/10.1016/S0016-5085(13)61466-3 Piedrahita, J. A., Koh, S., & Olby, N. (2012). GENERATION AND CHARACTERISATION OF INDUCED PLURIPOTENT STEM CELLS (iPSCs) FROM ADULT CANINE FIBROBLASTS. Reproduction, Fertility and Development, 24(1), 285. https://doi.org/10.1071/RDv24n1Ab244 Koh, S., Tsai, S., Bischoff, S., Thomas, R., Lim, J. H., Breen, M., … Piedrahita, J. (2012). Generation and characterization of induced pluripotent stem cells (iPS) from adult canine fibroblasts. Reproduction in Domestic Animals, 47, 418–419. Koh, S., Thomas, R., Tsai, S., Bischoff, S., Lim, J.-H., Breen, M., … Piedrahita, J. A. (2013). Growth Requirements and Chromosomal Instability of Induced Pluripotent Stem Cells Generated from Adult Canine Fibroblasts. Stem Cells and Development, 22(6), 951–963. https://doi.org/10.1089/scd.2012.0393 Lim, J.-H., Koh, S., Olby, N. J., Piedrahita, J., & Mariani, C. L. (2012). Isolation and characterization of neural progenitor cells from adult canine brains. American Journal of Veterinary Research, 73(12), 1963–1968. https://doi.org/10.2460/ajvr.73.12.1963 Chung, J., Tsai, S., James, A. H., Thames, B. H., Shytle, S., & Piedrahita, J. A. (2012). Lack of genomic imprinting of DNA primase, polypeptide 2 (PRIM2) in human term placenta and white blood cells. EPIGENETICS, 7(5), 429–431. https://doi.org/10.4161/epi.19777 Sommer, J. R., Jackson, L., Simpson, S., Collins, E. B., Piedrahita, J., & Petters, R. M. (2011). 336 TRANSGENIC Stra8-EYFP PIGS: A MODEL FOR DEVELOPING MALE GERM CELL TECHNOLOGIES. Reproduction, Fertility and Development, 23(1), 264. https://doi.org/10.1071/RDv23n1Ab336 Piedrahita, J. A., & Olby, N. (2011). Perspectives on transgenic livestock in agriculture and biomedicine: An update. Reproduction, Fertility and Development, 23(1), 56–63. Piedrahita, J. A., & Olby, N. (2011). Perspectives on transgenic livestock in agriculture and biomedicine: an update. Reproduction, Fertility and Development, 23(1), 56. https://doi.org/10.1071/RD10246 Sommer, J. R., Estrada, J. L., Collins, E. B., Bedell, M., Alexander, C. A., Yang, Z., … Zhang, K. (2011). Production of ELOVL4 transgenic pigs: a large animal model for Stargardt-like macular degeneration. British Journal of Ophthalmology, 95(12), 1749–1754. https://doi.org/10.1136/bjophthalmol-2011-300417 Piedrahita, J. A. (2011). [Review of The Role of Imprinted Genes in Fetal Growth Abnormalities]. BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY, 91(8), 682–692. https://doi.org/10.1002/bdra.20795 Sommer, J. R., Jackson, L. R., Simpson, S. G., Collins, E. B., Piedrahita, J. A., & Petters, R. M. (2012). Transgenic Stra8-EYFP pigs: a model for developing male germ cell technologies. TRANSGENIC RESEARCH, 21(2), 383–392. https://doi.org/10.1007/s11248-011-9542-6 Lim, J.-H., Piedrahita, J. A., Jackson, L., Ghashghaei, T., & Olby, N. J. (2010). Development of a Model of Sacrocaudal Spinal Cord Injury in Cloned Yucatan MiniPigs for Cellular Transplantation Research. CELLULAR REPROGRAMMING, 12(6), 689–697. https://doi.org/10.1089/cell.2010.0039 Lim, J.-H., Boozer, L., Mariani, C. L., Piedrahita, J. A., & Olby, N. J. (2010). Generation and Characterization of Neurospheres from Canine Adipose Tissue-Derived Stromal Cells. CELLULAR REPROGRAMMING, 12(4), 417–425. https://doi.org/10.1089/cell.2009.0093 Tsai, S., Hardison, N. E., James, A. H., Motsinger-Reif, A. A., Bischoff, S. R., Thames, B. H., & Piedrahita, J. A. (2011). Transcriptional profiling of human placentas from pregnancies complicated by preeclampsia reveals disregulation of sialic acid acetylesterase and immune signalling pathways. PLACENTA, 32(2), 175–182. https://doi.org/10.1016/j.placenta.2010.11.014 McCalla-Martin, A. C., Chen, X., Linder, K. E., Estrada, J. L., & Piedrahita, J. A. (2010). Varying phenotypes in swine versus murine transgenic models constitutively expressing the same human Sonic hedgehog transcriptional activator, K5-HGLI2ΔN. Transgenic Research, 19(5), 869–887. https://doi.org/10.1007/s11248-010-9362-0 Bischoff, S. R., Tsai, S., Hardison, N., Motsinger-Reif, A. A., Freking, B. A., Nonneman, D., … Piedrahita, J. A. (2009). Characterization of Conserved and Nonconserved Imprinted Genes in Swine. BIOLOGY OF REPRODUCTION, 81(5), 906–920. https://doi.org/10.1095/biolreprod.109.078139 Caballero, I., & Piedrahita, J. A. (2009). EVALUATION OF THE SERRATIA MARCESCENS NUCLEASE (NucA) AS A TRANSGENIC CELL ABLATION SYSTEM IN PORCINE. ANIMAL BIOTECHNOLOGY, 20(4), 177–185. https://doi.org/10.1080/10495390903048235 Farmer, W. T., Farin, P. W., Bischoff, S. R., Alexander, J. E., Piedrahita, J. A., & Farin, C. E. (2008). 2 DETECTION OF ANTISENSE TO Igf2r (AIR) RNA IN CATTLE. Reproduction, Fertility and Development, 20(1), 81. https://doi.org/10.1071/RDv20n1Ab2 Tsai, S., Hardison, N., Bischoff, S., Thames, B., Jamessd, A., Motsinger-Reif, A., & Piedrahita, J. (2008). 262: Molecular signatures of preeclampsia in human term placentas. American Journal of Obstetrics and Gynecology, 199(6), S84. https://doi.org/10.1016/j.ajog.2008.09.290 Lee, E., Estrada, J., & Piedrahita, J. A. (2008). A comparative study on the efficiency of two enucleation methods in pig somatic cell nuclear transfer: Effects of the squeezing and the aspiration methods. ANIMAL BIOTECHNOLOGY, 19(2), 71–79. https://doi.org/10.1080/10495390701839264 Zaunbrecher, G. M., Mir, B., Dunne, P. W., Breen, M., & Piedrahita, J. A. (2008). Enhancement of extra chromosomal recombination in somatic cells by affecting the ratio of homologous recombination (HR) to non-homologous end joining (NHEJ). ANIMAL BIOTECHNOLOGY, 19(1), 6–21. https://doi.org/10.1080/10495390701670099 Bischoff, S. R., Tsai, S., Hardison, N. E., York, A. M., Freking, B. A., Nonneman, D., … Piedrahita, J. A. (2008). Identification of SNPs and INDELS in swine transcribed sequences using short oligonucleotide microarrays. BMC Genomics, 9(1), 252. https://doi.org/10.1186/1471-2164-9-252 Estrada, J. L., Collins, B., York, A., Bischoff, S., Sommer, J., Tsai, S., … Piedrahita, J. A. (2008, June). Successful cloning of the Yucatan minipig using commercial/occidental breeds as oocyte donors and embryo recipients. CLONING AND STEM CELLS, Vol. 10, pp. 287–296. https://doi.org/10.1089/clo.2008.0005 Estrada, J., Sommer, J., Collins, B., Mir, B., Martin, A., York, A., … Piedrahita, J. A. (2007). Swine generated by somatic cell nuclear transfer have increased incidence of intrauterine growth restriction (IUGR). CLONING AND STEM CELLS, 9(2), 229–236. https://doi.org/10.1089/clo.2006.0079 Piedrahita, J., Bischoff, S., Estrada, J., Freking, B., Nonneman, D., Martin, A., … Tsai, S. 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