Jeffrey Yoder

Also known as: Jeffrey A. Yoder. Jeffrey Alan Yoder

https://orcid.org/0000-0002-6083-1311

immunology, immunogenetics, immunotoxicity, genomics, DNA methylation, DNA methyltransferases

Dr. Jeff Yoder graduated from Worcester Polytechnic Institute with a B.S. in Biotechnology and performed his graduate work with Dr. Tim Bestor receiving his Ph.D. in Cell and Developmental Biology from Harvard University’s graduate program in Biological and Biomedical Sciences. He then did a post-doc with Dr. Gary Litman at the University of South Florida. Jeff was faculty at the University of South Florida before joined the faculty at NC State University in 2004. Jeff's current research interests are on identifying and characterizing novel mediators of innate immunity. His research employs the zebrafish model to study the genetic and functional evolution of innate immune receptors, for examining the immunotoxicological effects of environmental chemicals, and as a model for identifying novel mediators of immunity. His current studies on the evolution of immune receptors integrates genomic and transcriptomic data from all vertebrate lineages. His current immunotoxicology research employs zebrafish and cell culture models to study the impact of exposure to per- and polyfluoroalkyl substances (PFAS) on immune function. This research is highly interdisciplinary and includes collaborations with evolutionary biologists, structural biochemists, toxicologists, chemists, engineers and field biologists. His research has been funded by NIH, NIEHS, NSF, MAF, TriCEM and a variety of foundations and agencies.

Works (91)

2020 chapter

Chapter 19 - Immunology

In The Zebrafish in Biomedical Research.

Source: ORCID
Added: December 20, 2019

2020 journal article

In vivo assessment of respiratory burst inhibition by xenobiotic exposure using larval zebrafish

Journal of Immunotoxicology.

By: D. Phelps, A. Fletcher, I. Rodriguez-Nunez, M. Balik-Meisner, D. Tokarz, D. Reif, D. Germolec, J. Yoder

Source: ORCID
Added: May 15, 2020

2020 journal article

Transcriptome Ortholog Alignment Sequence Tools (TOAST) for phylogenomic dataset assembly

BMC Evolutionary Biology, 20(1).

By: D. Wcisel, J. Howard, J. Yoder & A. Dornburg

Source: ORCID
Added: March 31, 2020

2019 journal article

Calcium imaging of primary canine sensory neurons: Small‐diameter neurons responsive to pruritogens and algogens

Brain and Behavior, 9.

By: J. Ganchingco, T. Fukuyama, J. Yoder & W. Bäumer

Source: ORCID
Added: October 1, 2019

2019 journal article

Circulating tumor cells exit circulation while maintaining multicellularity, augmenting metastatic potential.

Journal of Cell Science.

Source: ORCID
Added: September 21, 2019

2019 journal article

Presence of cerebrospinal fluid antibodies associated with autoimmune encephalitis of humans in dogs with neurologic disease

Journal of Veterinary Internal Medicine, 33(5), 2175–2182.

By: E. Stafford, A. Kortum, A. Castel, L. Green, J. Lau, P. Early, K. Muñana, C. Mariani, J. Yoder, N. Olby

Source: ORCID
Added: September 9, 2019

2018 journal article

Ligand-mediated protein degradation reveals functional conservation among sequence variants of the CUL4-type E3 ligase substrate receptor cereblon

Journal of Biological Chemistry, 293(16), 6187–6200.

By: A. Akuffo, A. Alontaga, R. Metcalf, M. Beatty, A. Becker, J. McDaniel, R. Hesterberg, W. Goodheart ...

Sources: ORCID, Crossref
Added: February 13, 2019

2018 journal article

Use of a specific polyclonal anti-canine TSLP antibody reveals TSLP expression in normal tissue and cell culture

Journal of Veterinary Pharmacology and Therapeutics, 41, 153–153.

By: J. Ganchingco, J. Yoder & W. Baumer

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Disruption of Trim9 function abrogates macrophage motility in vivo

Journal of Leukocyte Biology, 102(6), 1371–1380.

By: D. Tokarz, A. Heffelfinger, D. Jima, J. Gerlach, R. Shah, I. Rodriguez-Nunez, A. Kortum, A. Fletcher ...

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2017 journal article

Evolutionary divergence of the vertebrate TNFAIP8 gene family: Applying the spotted gar orthology bridge to understand ohnolog loss in teleosts

PLOS ONE, 12(6), e0179517.

By: C. Sullivan, C. Lage, J. Yoder, J. Postlethwait & C. Kim

Ed(s): P. Boudinot

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2017 journal article

Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling

Development, 144(16), 2925–2939.

By: Y. Chernyavskaya, R. Mudbhary, C. Zhang, D. Tokarz, V. Jacob, S. Gopinath, X. Sun, S. Wang ...

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2017 journal article

Spotted Gar and the Evolution of Innate Immune Receptors

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, 328(7), 666–684.

By: D. Wcisel, T. Ota, G. Litman & J. Yoder

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2016 journal article

A Review of Automated Microinjection Systems for Single Cells in the Embryogenesis Stage

IEEE/ASME Transactions on Mechatronics, 21(5), 2391–2404.

By: S. Permana, E. Grant, G. Walker & J. Yoder

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2016 journal article

Alternative haplotypes of antigen processing genes in zebrafish diverged early in vertebrate evolution

Proceedings of the National Academy of Sciences, 113(34), E5014–E5023.

By: S. McConnell, K. Hernandez, D. Wcisel, R. Kettleborough, D. Stemple, J. Yoder, J. Andrade, J. de Jong

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2016 journal article

Angiopellosis as an Alternative Mechanism of Cell Extravasation

STEM CELLS, 35(1), 170–180.

By: T. Allen, D. Gracieux, M. Talib, D. Tokarz, M. Hensley, J. Cores, A. Vandergriff, J. Tang ...

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2016 journal article

Erratum: Corrigendum: The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons

Nature Genetics, 48(6), 700–700.

By: I. Braasch, A. Gehrke, J. Smith, K. Kawasaki, T. Manousaki, J. Pasquier, A. Amores, T. Desvignes ...

Sources: Crossref, ORCID
Added: July 27, 2019

2016 journal article

Phage display and structural studies reveal plasticity in substrate specificity of caspase-3a from zebrafish

Protein Science, 25(11), 2076–2088.

By: M. Tucker, S. MacKenzie, J. Maciag, H. Dirscherl Ackerman, P. Swartz, J. Yoder, P. Hamilton, A. Clay Clark

Sources: ORCID, Crossref
Added: February 13, 2019

2016 journal article

Single-cell transcriptional analysis of normal, aberrant, and malignant hematopoiesis in zebrafish

The Journal of Cell Biology, 213(3), 2133OIA95.

By: F. Moore, E. Garcia, R. Lobbardi, E. Jain, Q. Tang, J. Moore, M. Cortes, A. Molodtsov ...

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2016 journal article

Single-cell transcriptional analysis of normal, aberrant, and malignant hematopoiesis in zebrafish

The Journal of Experimental Medicine, 213(6), 979–992.

By: F. Moore, E. Garcia, R. Lobbardi, E. Jain, Q. Tang, J. Moore, M. Cortes, A. Molodtsov ...

Sources: Crossref, ORCID
Added: July 27, 2019

2016 journal article

The confounding complexity of innate immune receptors within and between teleost species

Fish & Shellfish Immunology, 53, 24–34.

By: D. Wcisel & J. Yoder

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2016 journal article

The identification of additional zebrafish DICP genes reveals haplotype variation and linkage to MHC class I genes

Immunogenetics, 68(4), 295–312.

By: I. Rodriguez-Nunez, D. Wcisel, R. Litman, G. Litman & J. Yoder

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2016 journal article

The identification of additional zebrafish DICP genes reveals haplotype variation and linkage to MHC class I genes.

By: I. Rodriguez-Nunez, D. Wcisel, R. Litman, G. Litman & J. Yoder

Source: ORCID
Added: February 13, 2019

2016 journal article

The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons

Nature Genetics, 48(4), 427–437.

By: I. Braasch, A. Gehrke, J. Smith, K. Kawasaki, T. Manousaki, J. Pasquier, A. Amores, T. Desvignes ...

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2015 journal article

A nonclassical MHC class I U lineage locus in zebrafish with a null haplotypic variant

Immunogenetics, 67(9), 501–513.

By: H. Dirscherl & J. Yoder

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2015 journal article

Machine learning reveals sex-specific 17β-estradiol-responsive expression patterns in white perch (Morone americana) plasma proteins

PROTEOMICS, 15(15), 2678–2690.

By: J. Schilling, A. Nepomuceno, A. Planchart, J. Yoder, R. Kelly, D. Muddiman, H. Daniels, N. Hiramatsu, B. Reading

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2014 journal article

Differential expression and ligand binding indicate alternative functions for zebrafish polymeric immunoglobulin receptor (pIgR) and a family of pIgR-like (PIGRL) proteins

Immunogenetics, 66(4), 267–279.

By: A. Kortum, I. Rodriguez-Nunez, J. Yang, J. Shim, D. Runft, M. O’Driscoll, R. Haire, J. Cannon ...

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2014 journal article

Multigene families of immunoglobulin domain-containing innate immune receptors in zebrafish: Deciphering the differences

Developmental & Comparative Immunology, 46(1), 24–34.

By: I. Rodríguez-Nunez, D. Wcisel, G. Litman & J. Yoder

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2014 journal article

Neutralization of Mitochondrial Superoxide by Superoxide Dismutase 2 Promotes Bacterial Clearance and Regulates Phagocyte Numbers in Zebrafish

Infection and Immunity, 83(1), 430–440.

By: E. Peterman, C. Sullivan, M. Goody, I. Rodriguez-Nunez, J. Yoder & C. Kim

Ed(s): B. McCormick

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2014 journal article

Preface to the Special Issue: Zebrafish immunity and infection models

Developmental & Comparative Immunology, 46(1), 1–2.

By: J. Yoder

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2014 journal article

The MHC class I genes of zebrafish

Developmental & Comparative Immunology, 46(1), 11–23.

By: H. Dirscherl, S. McConnell, J. Yoder & J. de Jong

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2013 journal article

A Myristoylated Alanine-Rich C Kinase Substrate–Related Peptide Suppresses Cytokine mRNA and Protein Expression in LPS-Activated Canine Neutrophils

American Journal of Respiratory Cell and Molecular Biology, 48(3), 314–321.

By: J. Li, M. D’Annibale-Tolhurst, K. Adler, S. Fang, Q. Yin, A. Birkenheuer, M. Levy, S. Jones ...

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2013 journal article

A semantic model for species description applied to the ensign wasps (Hymenoptera: Evaniidae) of New Caledonia

Systematic Biology, 62(5), 639–659.

By: J. Balhoff, I. Miko, M. Yoder, P. Mullins & A. Deans

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2013 journal article

An ITAM in a Nonenveloped Virus Regulates Activation of NF- B, Induction of Beta Interferon, and Viral Spread

Journal of Virology, 88(5), 2572–2583.

By: R. Stebbing, S. Irvin, E. Rivera-Serrano, K. Boehme, M. Ikizler, J. Yoder, T. Dermody, B. Sherry, D. Lyles

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2013 journal article

Characterization of the Z lineage Major histocompatability complex class I genes in zebrafish

Immunogenetics, 66(3), 185–198.

By: H. Dirscherl & J. Yoder

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2013 journal article

Super Resolution Microscopy Reveals that Caveolin-1 Is Required for Spatial Organization of CRFB1 and Subsequent Antiviral Signaling in Zebrafish

PLoS ONE, 8(7), e68759.

By: K. Gabor, C. Stevens, M. Pietraszewski, T. Gould, J. Shim, J. Yoder, S. Lam, Z. Gong ...

Ed(s): C. Lamaze

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2012 journal article

Development and Characterization of Anti-Nitr9 Antibodies

Advances in Hematology, 2012, 1–9.

By: R. Shah, I. Rodriguez-Nunez, D. Eason, R. Haire, J. Bertrand, V. Wittamer, D. Traver, S. Nordone ...

Sources: ORCID, Crossref
Added: February 13, 2019

2012 journal article

Genomic and functional characterization of the diverse immunoglobulin domain-containing protein (DICP) family

Genomics, 99(5), 282–291.

By: R. Haire, J. Cannon, M. O'Driscoll, D. Ostrov, M. Mueller, P. Turner, R. Litman, G. Litman, J. Yoder

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2012 conference paper

Myristoylated Alanine-Rich C Kinase Substrate (MARCKS) Protein Plays A Critical Role In Production Of Proinflammatory Cytokines By Isolated Canine Neutrophils

A67. ACUTE LUNG INJURY AND ACUTE RESPIRATORY DISTRESS SYNDROME: BIOLOGICAL MECHANISMS.

By: S. Nordone, J. Li, M. D’Annibale, A. Birkenheuer, M. Levy, J. Yoder, S. Jones, K. Adler

Source: ORCID
Added: February 13, 2019

2012 journal article

Surface modifications on InAs decrease indium and arsenic leaching under physiological conditions

Applied Surface Science, 261, 842–850.

By: S. Jewett, J. Yoder & A. Ivanisevic

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2011 journal article

A photoactivatable small-molecule inhibitor for light-controlled spatiotemporal regulation of Rho kinase in live embryos

Development, 139(2), 437–442.

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2011 journal article

Expression and function of triggering receptor expressed on myeloid cells-1 (TREM-1) on canine neutrophils

Developmental & Comparative Immunology, 35(8), 872–880.

By: J. Li, A. Birkenheuer, H. Marr, M. Levy, J. Yoder & S. Nordone

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2011 journal article

Two Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) Paralogs are Required for Normal Development in Zebrafish

The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology, 294(9), 1511–1524.

By: L. Ott, Z. Mcdowell, P. Turner, J. Law, K. Adler, J. Yoder, S. Jones

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2010 journal article

Photocaged Morpholino Oligomers for the Light-Regulation of Gene Function in Zebrafish and Xenopus Embryos

Journal of the American Chemical Society, 132(44), 15644–15650.

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2010 journal article

Specific Resistance to Pseudomonas aeruginosa Infection in Zebrafish Is Mediated by the Cystic Fibrosis Transmembrane Conductance Regulator

Infection and Immunity, 78(11), 4542–4550.

By: R. Phennicie, M. Sullivan, J. Singer, J. Yoder & C. Kim

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2010 journal article

The phylogenetic origins of natural killer receptors and recognition: relationships, possibilities, and realities

Immunogenetics, 63(3), 123–141.

By: J. Yoder & G. Litman

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2009 journal article

Aquatic animal models of human disease: Selected papers and recommendations from the 4th Conference

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 149(2), 121–128.

By: D. Hinton, R. Hardman, S. Kullman, J. Law, M. Schmale, R. Walter, R. Winn, J. Yoder

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2009 journal article

Developmental and tissue-specific expression of NITRs

Immunogenetics, 62(2), 117–122.

By: J. Yoder, P. Turner, P. Wright, V. Wittamer, J. Bertrand, D. Traver, G. Litman

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2009 journal article

Enhanced transcription of complement and coagulation genes in the absence of adaptive immunity

Molecular Immunology, 46(7), 1505–1516.

By: D. Jima, R. Shah, T. Orcutt, D. Joshi, J. Law, G. Litman, N. Trede, J. Yoder

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2009 journal article

Form, function and phylogenetics of NITRs in bony fish

Developmental & Comparative Immunology, 33(2), 135–144.

By: J. Yoder

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2009 journal article

Light-activation of gene function in mammalian cells via ribozymes

Chem. Commun., (5), 568–570.

By: D. Young, R. Garner, J. Yoder & A. Deiters

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2009 journal article

Sp2 Is a Maternally Inherited Transcription Factor Required for Embryonic Development

Journal of Biological Chemistry, 285(6), 4153–4164.

By: J. Xie, H. Yin, T. Nichols, J. Yoder & J. Horowitz

Sources: ORCID, Crossref
Added: February 13, 2019

2008 journal article

A critical role for DAP10 and DAP12 in CD8+ T cell-mediated tissue damage in large granular lymphocyte leukemia

Blood, 113(14), 3226–3234.

By: X. Chen, F. Bai, L. Sokol, J. Zhou, A. Ren, J. Painter, J. Liu, D. Sallman ...

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2008 journal article

Assessing infection and immunity in zebrafish

Zebrafish, 5(3), 189–191.

By: J. Yoder

Source: ORCID
Added: February 13, 2019

2008 journal article

Clinical improvement by farnesyltransferase inhibition in NK large granular lymphocyte leukemia associated with imbalanced NK receptor signaling

Blood, 112(12), 4694–4698.

By: P. Epling-Burnette, L. Sokol, X. Chen, F. Bai, J. Zhou, M. Blaskovich, J. Zou, J. Painter ...

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2008 journal article

Evidence for a transposition event in a second NITR gene cluster in zebrafish

Immunogenetics, 60(5), 257–265.

By: J. Yoder, J. Cannon, R. Litman, C. Murphy, J. Freeman & G. Litman

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2008 journal article

Gene Silencing in Mammalian Cells with Light-Activated Antisense Agents

ChemBioChem, 9(18), 2937–2940.

By: D. Young, H. Lusic, M. Lively, J. Yoder & A. Deiters

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2008 journal article

The medaka novel immune-type receptor (NITR) gene clusters reveal an extraordinary degree of divergence in variable domains

BMC Evolutionary Biology, 8(1), 177.

By: S. Desai, A. Heffelfinger, T. Orcutt, G. Litman & J. Yoder

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2008 journal article

Workshop report - assessing infection and immunity in zebrafish

Zebrafish, 5, 189–191.

By: J. Yoder

Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

Immunoglobulin variable regions in molecules exhibiting characteristics of innate and adaptive immune receptors

Immunologic Research, 38(1-3), 294–304.

By: G. Litman, J. Cannon, L. Dishaw, R. Haire, D. Eason, J. Yoder, J. Prada, D. Ostrov

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2007 journal article

Structural characteristics of zebrafish orthologs of adaptor molecules that associate with transmembrane immune receptors

Gene, 401(1-2), 154–164.

By: J. Yoder, T. Orcutt, D. Traver & G. Litman

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2007 journal article

The zebrafish activating immune receptor Nitr9 signals via Dap12

Immunogenetics, 59(10), 813–821.

By: S. Wei, J. Zhou, X. Chen, R. Shah, J. Liu, T. Orcutt, D. Traver, J. Djeu ...

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2006 journal article

Conditional Transgene and Gene Targeting Methodologies in Zebrafish

Zebrafish, 3(4), 415–429.

By: A. Deiters & J. Yoder

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2006 journal article

Immune-related, lectin-like receptors are differentially expressed in the myeloid and lymphoid lineages of zebrafish

Immunogenetics, 58(1), 31–40.

By: P. Panagos, K. Dobrinski, X. Chen, A. Grant, D. Traver, J. Djeu, S. Wei, J. Yoder

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2006 journal article

Methylation of tRNAAsp by the DNA Methyltransferase Homolog Dnmt2

Science, 311(5759), 395–398.

By: M. Goll, F. Kirpekar, K. Maggert, J. Yoder, C. Hsieh, X. Zhang, K. Golic, S. Jacobsen, T. Bestor

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2006 journal article

Role for retinoid signaling in left–right asymmetric digestive organ morphogenesis

Developmental Dynamics, 235(8), 2266–2275.

By: K. Lipscomb, C. Schmitt, A. Sablyak, J. Yoder & N. Nascone-Yoder

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2004 journal article

Investigating the morphology, function and genetics of cytotoxic cells in bony fish

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 138(3), 271–280.

By: J. Yoder

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2004 journal article

On the origins of adaptive immunity: Innate immune receptors join the tale

Trends in Immunology, 25(1), 11–16.

By: T. Van Den Berg, J. Yoder & G. Litman

Source: ORCID
Added: February 13, 2019

2004 journal article

On the origins of adaptive immunity:possible clues from the SIRP and NITR multigene families

Trends in Immunology, 25, 11–16.

By: T. Berg, J. Yoder & G. Litman

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

Resolution of the novel immune-type receptor gene cluster in zebrafish

Proceedings of the National Academy of Sciences, 101(44), 15706–15711.

By: J. Yoder, R. Litman, M. Mueller, S. Desai, K. Dobrinski, J. Montgomery, M. Buzzeo, T. Ota ...

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2003 journal article

Novel Immune-type Receptor Genes and the Origins of Adaptive and Innate Immune Recognition

Integrative and Comparative Biology, 43(2), 331–337.

By: G. Litman, J. Yoder, J. Cannon & R. Haire

Sources: NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2003 article

The Zebrafish as a Model Organism to Study Development of the Immune System

Advances in Immunology, Vol. 81, pp. 254–330.

By: D. Traver, P. Herbomel, E. Patton, R. Murphey, J. Yoder, G. Litman, A. Catic, C. Amemiya ...

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2002 journal article

BIVM, a Novel Gene Widely Distributed among Deuterostomes, Shares a Core Sequence with an Unusual Gene in Giardia lamblia

Genomics, 79(6), 750–755.

By: J. Yoder, N. Hawke, D. Eason, M. Mueller, B. Davids, F. Gillin, G. Litman

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2002 journal article

Cloning novel immune-type inhibitory receptors from the rainbow trout, Oncorhynchus mykiss

Immunogenetics, 54(9), 662–670.

By: J. Yoder, G. Mueller, K. Nichols, S. Ristow, G. Thorgaard, T. Ota, G. Litman

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2002 journal article

Zebrafish as an immunological model system

Microbes and Infection, 4(14), 1469–1478.

By: J. Yoder, M. Nielsen, C. Amemiya & G. Litman

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2001 journal article

Cloning and sequence analysis of a zebrafish cDNA encoding DNA (cytosine-5)-methyltransferase-1

Genesis, 30(4), 213–219.

By: A. Mhanni, J. Yoder, C. Dubesky & R. McGowan

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2001 journal article

Corrigendum to: “The zebrafish fth1, slc3a2, men1, pc, fgf3 and cycd1 genes define two regions of conserved synteny between linkage group 7 and human chromosome 11q13” [Gene 261 (2000) 235–242]

Gene, 269(1-2), 227.

By: J. Yoder & G. Litman

Source: ORCID
Added: February 13, 2019

2001 journal article

Extraordinary variation in a diversified family of immune-type receptor genes

Proceedings of the National Academy of Sciences, 98(24), 13832–13837.

By: N. Hawke, J. Yoder, R. Haire, M. Mueller, R. Litman, A. Miracle, T. Stuge, L. Shen ...

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2001 journal article

Immune-type receptor genes in zebrafish share genetic and functional properties with genes encoded by the mammalian leukocyte receptor cluster

Proceedings of the National Academy of Sciences, 98(12), 6771–6776.

By: J. Yoder, M. Mueller, S. Wei, B. Corliss, D. Prather, T. Willis, R. Litman, J. Djeu, G. Litman

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2001 journal article

Novel immune-type receptor genes

Immunol Rev, 181(1), 250–259.

By: G. Litman, N. Hawke & J. Yoder

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2001 journal article

Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA

Nucleic Acids Research, 29(2), 439–448.

By: A. Dong, J. Yoder, X. Zhang, L. Zhou, T. Bestor & X. Cheng

Sources: NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2000 chapter

Immune-Type Diversity in the Absence of Somatic Rearrangement

In Current Topics in Microbiology and Immunology (Vol. 248, pp. 271–282).

By: J. Yoder & G. Litman

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2000 journal article

The zebrafish fth1, slc3a2, men1, pc, fgf3 and cycd1 genes define two regions of conserved synteny between linkage group 7 and human chromosome 11q13

Gene, 261(2), 235–242.

By: J. Yoder & G. Litman

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

1999 journal article

Cloning of two zebrafish cDNAs that share domains with the MHC class II-associated invariant chain

Immunogenetics, 50(1-2), 84–88.

By: J. Yoder, R. Haire & G. Litman

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

1999 journal article

Expanding our understanding of immunoglobulin, T-cell antigen receptor, and novel immune-type receptor genes: A subset of the immunoglobulin gene superfamily

Immunogenetics, 50(3-4), 124–133.

By: N. Hawke, J. Yoder & G. Litman

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

1998 journal article

A candidate mammalian DNA methyltransferase related to pmt1p of fission yeast

Human Molecular Genetics, 7(2), 279–284.

By: J. Yoder & T. Bestor

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

1998 journal article

Sex-specific exons control DNA methyltransferase in mammalian germ cells

Development, 125(5), 889–897.

By: C. Mertineit, J. Yoder, T. Taketo, D. Laird, J. Trasler & T. Bestor

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

1997 journal article

Cytosine methylation and the ecology of intragenomic parasites

Trends in Genetics, 13(8), 335–340.

By: J. Yoder, C. Walsh & T. Bestor

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

1997 journal article

DNA (cytosine-5)-methyltransferases in mouse cells and tissues. studies with a mechanism-based probe

Journal of Molecular Biology, 270(3), 385–395.

By: J. Yoder, N. Soman, G. Verdine & T. Bestor

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

1996 journal article

Genetic analysis of genomic methylation patterns in plants and mammals

Biological Chemistry, 377(10), 605–610.

By: J. Yoder & T. Bestor

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

1996 journal article

New 5′ Regions of the Murine and Human Genes for DNA (Cytosine-5)-methyltransferase

Journal of Biological Chemistry, 271(49), 31092–31097.

By: J. Yoder, R. Chiu Yen, P. Vertino, T. Bestor & S. Baylin

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

1991 journal article

Cross-linking a maturation-dependent ram sperm plasma membrane antigen induces the acrosome reaction

Molecular Reproduction and Development, 29(2), 200–207.

By: C. McKinnon, F. Weaver, J. Yoder, G. Fairbanks & D. Wolf

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

Employment

2019 - present

North Carolina State University Raleigh, NC, US
Professor Department of Molecular Biomedical Sciences

2010 - 2019

North Carolina State University Raleigh, NC, US
Associate Professor Department of Molecular Biomedical Sciences

2004 - 2010

North Carolina State University Raleigh, NC, US
Assistant Professor Department of Molecular Biomedical Sciences

2002 - 2004

University of South Florida Tampa, FL, US
Assistant Professor Department of Biology

1998 - 2002

University of South Florida St. Petersburg, FL, US
Postdoctoral fellow Department of Pediatrics

Education

1990 - 1997

Harvard University Cambridge, MA, US
Ph.D. Cell and Developmental Biology

1986 - 1990

Worcester Polytechnic Institute Worcester, MA, US
B.S. Biology and Biotechnology

Funding History

Funding history based on the linked ORCID record.

grant February 28, 2020 - January 31, 2025
Center for Environmental and Health Effects of PFAS
National Institute of Environmental Health Sciences
grant April 1, 2018 - March 31, 2021
Collaborative Research: Understanding the molecular diversification of self recognition through ray-finned fish innate immune receptor families
Directorate for Biological Sciences
grant April 1, 2017 - March 31, 2018
Conference: From Omics to Function, Future Directions for Comparative Immunology, NACI Workshop, June 12-15, 2017, Raleigh, North Carolina
Directorate for Biological Sciences
contract September 1, 2014 - September 1, 2016
Zebrafish immune function and disease resistance assays
National Institute of Environmental Health Sciences
grant June 15, 2008 - November 30, 2010
Whole organism transcriptional profiling of innate immune response
National Institute of Allergy and Infectious Diseases
grant December 1, 2004 - July 1, 2015
Novel Innate Immune Receptors in Zebrafish
National Institutes of Health
grant April 5, 2004 - March 31, 2007
Novel Immune-Type Receptors and Cytotoxicity In Zebrafish
National Science Foundation - Directorate for Biological Sciences
grant August 1, 1999 - January 1, 2001
NOVEL IMMUNE TYPE RECEPTOR (NITR) GENES IN ZEBRAFISH
National Institute of General Medical Sciences