2015 review

Cross-species coherence in effects and modes of action in support of causality determinations in the US Environmental Protection Agency's Integrated Science Assessment for Lead

[Review of ]. TOXICOLOGY, 330, 19–40.

By: M. Lassiter*, E. Owens*, M. Patel*, E. Kirrane*, M. Madden*, J. Richmond-Bryant*, E. Hines*, J. Davis*, L. Vinikoor-Imler*, J. Dubois n

Contributors: M. Lassiter*, E. Owens*, M. Patel*, E. Kirrane*, M. Madden*, J. Richmond-Bryant*, E. Hines*, J. Davis*, L. Vinikoor-Imler*, J. Dubois n

author keywords: Cross-species; Mode of action; Lead; Biological plausibility; Causality; Coherence
MeSH headings : Animals; Environmental Pollutants / metabolism; Environmental Pollutants / toxicity; Hematologic Diseases / chemically induced; Hematologic Diseases / genetics; Hematologic Diseases / metabolism; Humans; Lead / metabolism; Lead / toxicity; Species Specificity; United States; United States Environmental Protection Agency / trends
TL;DR: The integration of coherent effects and common underlying modes of action can serve as a means to substantiate conclusions regarding the causal nature of the health and ecological effects of environmental toxicants. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

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