Jenny B. Ferrell

Works (15)

Updated: July 28th, 2023 21:14
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2012 journal article

Ceruloplasmin alters intracellular iron regulated proteins and pathways: Ferritin, transferrin receptor, glutamate and hypoxia-inducible factor-1Ξ±

Experimental Eye Research, 97(1), 90–97.

By: J. Harned n, J. Ferrell n, S. Nagar n, M. Goralska n, L. Fleisher n & M. McGahan n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: ceruloplasmin; iron; lens epithelial cells; retinal pigmented epithelial cells glutamate; hypoxia-inducible factor; transferrin receptor; ferritin
MeSH headings : Animals; Cells, Cultured; Ceruloplasmin / metabolism; Ceruloplasmin / pharmacology; Dogs; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Ferritins / metabolism; Fluorescent Antibody Technique, Indirect; Glutamic Acid / metabolism; Hypoxia-Inducible Factor 1, alpha Subunit / metabolism; Iron Chelating Agents / pharmacology; Lens, Crystalline / cytology; Oxalates / pharmacology; Receptors, Transferrin / metabolism; Retinal Pigment Epithelium / drug effects; Retinal Pigment Epithelium / metabolism
Sources: Web Of Science, Crossref
Added: August 6, 2018

2010 journal article

Altered Ferritin Subunit Composition: Change in Iron Metabolism in Lens Epithelial Cells and Downstream Effects on Glutathione Levels and VEGF Secretion

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 51(9), 4437–4446.

By: J. Harned n, J. Ferrell n, M. Lall n, L. Fleisher n, S. Nagar n, M. Goralska n, M. McGahan n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Animals; Apoferritins / genetics; Apoferritins / metabolism; Cell Nucleus / metabolism; Cells, Cultured; Culture Media, Conditioned / pharmacology; Cystine / pharmacokinetics; Dogs; Epithelial Cells / cytology; Epithelial Cells / metabolism; Glutathione / metabolism; Homeostasis / physiology; Hypoxia-Inducible Factor 1, alpha Subunit / metabolism; Iron / metabolism; Lens, Crystalline / cytology; Lens, Crystalline / metabolism; Oxidative Stress / physiology; Protein Subunits / genetics; Protein Subunits / metabolism; RNA, Small Interfering; Transfection; Vascular Endothelial Growth Factor A / metabolism
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Iron metabolism in the eye: A review

Experimental Eye Research, 88(2), 204–215.

By: M. Goralska n, J. Ferrell n, J. Harned n, M. Lall n, S. Nagar n, L. Fleisher n, M. McGahan n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: iron; ferritin; transferrin; lens; retinal pigmented epithelium; retina
MeSH headings : Animals; Eye / metabolism; Eye Diseases / metabolism; Homeostasis; Humans; Iron / metabolism; Oxidative Stress; Signal Transduction / physiology
Sources: Web Of Science, Crossref
Added: August 6, 2018

2008 journal article

Iron regulates L-cystine uptake and glutathione levels in lens epithelial and retinal pigment epithelial cells by its effect on cytosolic aconitase

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 49(1), 310–319.

By: M. Lall n, J. Ferrell n, S. Nagar n, L. Fleisher n & M. McGahan n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : 2,2'-Dipyridyl / pharmacology; Aconitate Hydratase / antagonists & inhibitors; Aconitate Hydratase / metabolism; Amino Acid Transport System y+ / genetics; Amino Acid Transport System y+ / metabolism; Animals; Cells, Cultured; Chelating Agents / pharmacology; Cystine / metabolism; Cytosol; Dogs; Enzyme Inhibitors / pharmacology; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Fluorescent Antibody Technique, Indirect; Gene Expression; Glutathione / metabolism; Immunoblotting; Lens, Crystalline / drug effects; Lens, Crystalline / metabolism; Oxalates / pharmacology; Pigment Epithelium of Eye / metabolism; RNA, Messenger / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Transferrin / pharmacology
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Iron alters glutamate secretion by regulating cytosolic aconitase activity

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 288(5), C1117–C1124.

By: M. McGahan, J. Harned*, M. Mukunnemkeril, M. Goralska*, L. Fleisher* & J. Ferrell*

author keywords: retinal pigment epithelial cells; lens epithelial cells
MeSH headings : Aconitate Hydratase / antagonists & inhibitors; Aconitate Hydratase / metabolism; Animals; Cells, Cultured; Citric Acid / metabolism; Cytosol / metabolism; Dogs; Enzyme Activation / drug effects; Glutamates / metabolism; Iron / metabolism; Isocitrates / metabolism; Membrane Transport Proteins / metabolism; Oxalates / pharmacology; Pigment Epithelium of Eye / drug effects; Pigment Epithelium of Eye / enzymology; Riluzole / pharmacology; Vesicular Glutamate Transport Protein 1
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Rabbit pigmented ciliary epithelium produces interleukin-6 in response to inflammatory cytokines

EXPERIMENTAL EYE RESEARCH, 70(3), 271–279.

By: L. Fleisher n, M. McGahan n & J. Ferrell n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: interleukin-6; pigmented ciliary epithelium; interleukin-1; tumor necrosis factor-alpha; adenosine 3 ',5 '-cyclic monophosphate
MeSH headings : Animals; Cell Culture Techniques; Ciliary Body / immunology; Ciliary Body / metabolism; Cyclic AMP / metabolism; Cytokines / immunology; Endotoxins / immunology; Interleukin-1 / immunology; Interleukin-6 / biosynthesis; Pigment Epithelium of Eye / immunology; Pigment Epithelium of Eye / metabolism; Rabbits; Tumor Necrosis Factor-alpha / immunology
Source: Web Of Science
Added: August 6, 2018

1996 journal article

Interleukin-1 beta increases prostaglandin E(2)-stimulated adenosine 3',5'-cyclic monophosphate production in rabbit pigmented ciliary epithelium

EXPERIMENTAL EYE RESEARCH, 63(1), 91–104.

By: L. Fleisher n, M. McGahan n, J. Ferrell n & I. Pagan n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: ciliary epithelium; cyclic AMP, interleukin-1; prostaglandins; transforming growth factor-beta; pigmented ciliary epithelium
MeSH headings : Animals; Cells, Cultured; Colforsin / pharmacology; Cyclic AMP / biosynthesis; Cycloheximide / pharmacology; Cyclooxygenase Inhibitors / pharmacology; Dinoprostone / pharmacology; Dose-Response Relationship, Drug; Indomethacin / pharmacology; Interleukin-1 / pharmacology; Isoproterenol / pharmacology; Kinetics; Lipopolysaccharides / pharmacology; Pigment Epithelium of Eye / drug effects; Pigment Epithelium of Eye / metabolism; Protein Synthesis Inhibitors / pharmacology; Rabbits; Stimulation, Chemical; Transforming Growth Factor beta / pharmacology; Tumor Necrosis Factor-alpha / pharmacology; Up-Regulation; Vasoactive Intestinal Peptide / pharmacology
Source: Web Of Science
Added: August 6, 2018

1996 journal article

Nitric oxide synthase inhibitors exert differential time-dependent effects on LPS-induced uveitis

EXPERIMENTAL EYE RESEARCH, 62(1), 21–28.

By: J. Allen n, M. McGahan n, J. Ferrell n, K. Adler n & L. Fleisher n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: nitric oxide; uveitis; nitric oxide synthase; nitric oxide synthase inhibitors; inflammation
MeSH headings : Animals; Aqueous Humor / metabolism; Arginine / analogs & derivatives; Arginine / therapeutic use; Cell Count / drug effects; Dose-Response Relationship, Drug; Eye Proteins / drug effects; Guanidines / therapeutic use; Kinetics; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitric Oxide / antagonists & inhibitors; Nitric Oxide / physiology; Nitric Oxide Synthase / antagonists & inhibitors; Rabbits; Uveitis, Anterior / etiology; Uveitis, Anterior / metabolism; Uveitis, Anterior / prevention & control
Source: Web Of Science
Added: August 6, 2018

1995 journal article

INFLAMMATION-INDUCED CHANGES IN ADENOSINE 3',5'-CYCLIC-MONOPHOSPHATE PRODUCTION BY CILIARY EPITHELIAL-CELL BILAYERS

EXPERIMENTAL EYE RESEARCH, 60(2), 165–171.

By: L. Fleisher n, J. Ferrell n & M. Mcgahan n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE; INTERLEUKIN-1; TUMOR NECROSIS FACTOR; ANTERIOR UVEA; CILIARY EPITHELIUM; ENDOTOXIN; UVEITIS
MeSH headings : Animals; Ciliary Body / drug effects; Ciliary Body / metabolism; Colforsin / pharmacology; Culture Techniques; Cyclic AMP / biosynthesis; Epithelium / drug effects; Epithelium / metabolism; Interleukin-1 / pharmacology; Isoproterenol / pharmacology; Lipopolysaccharides / pharmacology; Male; Rabbits; Recombinant Proteins / pharmacology; Tumor Necrosis Factor-alpha / pharmacology; Uveitis, Anterior / etiology; Uveitis, Anterior / metabolism
Source: Web Of Science
Added: August 6, 2018

1995 journal article

MEDIATORS OF THE OCULAR INFLAMMATORY RESPONSE TO INTERLEUKIN-1-BETA PLUS TUMOR-NECROSIS-FACTOR-ALPHA

GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 233(2), 94–100.

By: L. Fleisher n, J. Ferrell n & C. Mcgahan n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Animals; Indomethacin / therapeutic use; Interleukin-1 / toxicity; Male; Platelet Activating Factor / antagonists & inhibitors; Platelet Activating Factor / metabolism; Rabbits; Tumor Necrosis Factor-alpha / toxicity; Uveitis, Anterior / immunology; Uveitis, Anterior / prevention & control; Uveitis, Posterior / immunology; Uveitis, Posterior / prevention & control
Source: Web Of Science
Added: August 6, 2018

1992 journal article

Effects of copper loading and depletion on rabbit superoxide dismutase activity

Trace Elements in Medicine, 9, 55–58.

By: J. Ferrell, L. Fleisher, M. Smith & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1992 journal article

Synergistic uveitic effects of tumor necrosis factor-alpha and interleukin-1 beta

Investigative Ophthalmology and Visual Science, 33, 2120–2127.

By: L. Fleisher, J. Ferrell & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1991 journal article

Lipid mediators of TNF- induced uveitis

Investigative Ophthalmology and Visual Science, 32, 2393–2399.

By: L. Fleisher, J. Ferrell & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1990 journal article

OCULAR INFLAMMATORY EFFECTS OF INTRAVITREALLY INJECTED TUMOR NECROSIS FACTOR-ALPHA AND ENDOTOXIN

INFLAMMATION, 14(3), 325–335.

By: L. Fleisher n, J. Ferrell n & M. Mcgahan n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
Source: Web Of Science
Added: August 6, 2018

1989 journal article

DIMETHYLTHIOUREA INHIBITS THE INFLAMMATORY RESPONSE TO INTRAVITREALLY-INJECTED ENDOTOXIN

EXPERIMENTAL EYE RESEARCH, 48(4), 561–567.

By: L. Fleisher n, J. Ferrell n, N. Olson n & M. Mcgahan n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Animals; Endotoxins; Escherichia coli; Male; Rabbits; Thiourea / administration & dosage; Thiourea / analogs & derivatives; Thiourea / pharmacology; Uveitis, Anterior / chemically induced; Uveitis, Anterior / prevention & control; Vitreous Body
Source: Web Of Science
Added: August 6, 2018