Works (3)

Updated: July 25th, 2023 21:16

2018 journal article

What is your diagnosis?

Journal of the American Veterinary Medical Association, 252(2), 173–175.

By: S. Almeida, H. Shive n, J. Harvey n, L. Borst n & E. Cohen n

Contributors: S. Bessauer Almeida, H. Shive n, J. Harvey n, L. Borst n & E. Cohen n

MeSH headings : Animals; Chickens; Diagnosis, Differential; Female; Hindlimb; Kidney Neoplasms / complications; Kidney Neoplasms / diagnostic imaging; Kidney Neoplasms / pathology; Kidney Neoplasms / veterinary; Lameness, Animal / diagnosis; Lameness, Animal / diagnostic imaging; Lameness, Animal / etiology; Marek Disease / complications; Marek Disease / diagnosis; Marek Disease / pathology; Muscular Atrophy / complications; Muscular Atrophy / diagnostic imaging; Muscular Atrophy / veterinary; Poultry Diseases / diagnosis; Poultry Diseases / diagnostic imaging; Poultry Diseases / etiology; Poultry Diseases / pathology; Radiography / veterinary; Sciatic Nerve / pathology; Ultrasonography / veterinary
TL;DR: On clinical examination, the dog was bright, alert and responsive with a body weight of 17.2kg and a body condition score of 5/9 and the mucous membranes were pink and moist, with a capillary refill time of one second. (via Semantic Scholar)
Sources: NC State University Libraries, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

F344/NTac Rats Chronically Exposed to Bromodichloroacetic Acid Develop Mammary Adenocarcinomas With Mixed Luminal/Basal Phenotype and Tgf beta Dysregulation

VETERINARY PATHOLOGY, 53(1), 170–181.

By: J. Harvey n, H. Hong*, S. Bhusari*, T. Ton*, Y. Wang*, J. Foley*, S. Peddada*, M. Hooth* ...

author keywords: breast cancer; basal; F344/NTac rat; gene expression; luminal; transforming growth factor beta; environmental pollutants
MeSH headings : Acetates / adverse effects; Adenocarcinoma / chemically induced; Adenocarcinoma / pathology; Animals; Female; Humans; Mammary Neoplasms, Experimental / chemically induced; Mammary Neoplasms, Experimental / pathology; Phenotype; Rats; Rats, Inbred F344; Transforming Growth Factor beta / metabolism
TL;DR: Gene expression analysis showed a positive trend in the number of genes associated with human breast cancer, with proportionally more genes represented in the BDCA-treated tumor group, and a 5-gene signature representing possible Tgfβ pathway activation in BD CA-treated adenocarcinomas was observed, suggesting that this pathway may be involved in the increased incidence of mammary tumors in BDca-exposed animals. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Uterine Carcinomas in Tetrabromobisphenol A-exposed Wistar Han Rats Harbor Increased Tp53 Mutations and Mimic High-grade Type I Endometrial Carcinomas in Women

TOXICOLOGIC PATHOLOGY, 43(8), 1103–1113.

By: J. Harvey n, T. Osborne*, H. Hong*, S. Bhusari*, T. Ton*, A. Pandiri*, T. Masinde*, J. Dunnick* ...

author keywords: tetrabromobisphenol A; dometrial carcinoma; Tp53; Ctnnb1; Kras; Ccnd1; Her2; Cdh1; Wistar Han rats
MeSH headings : Animals; Endometrial Neoplasms / genetics; Female; Humans; Immunohistochemistry; Mutation / genetics; Polybrominated Biphenyls / toxicity; Rats; Rats, Wistar; Tumor Suppressor Protein p53 / genetics; Uterine Neoplasms / chemically induced; Uterine Neoplasms / genetics; Uterine Neoplasms / metabolism; Uterus / chemistry; Uterus / pathology
TL;DR: The morphologic and molecular features of uterine carcinomas in T BBPA-exposed rats resemble those of high-grade type I tumors in women, and these data suggest that exposure to TBBPA may pose an increased cancer risk. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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