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Logan and Milton, Morgan E. and Feldmann, Erik A. and Bobay, Benjamin G. and Roth, Braden M. and Olson, Andrew L. and Thompson, Richele J. and Actis, Luis A. and Davies, Christopher and Cavanagh, John}, year={2018}, month={Mar}, pages={806–821} } @article{draughn_allen_routh_stone_kirker_boegli_schuchman_linder_baynes_james_et al._2017, title={Evaluation of a 2-aminoimidazole variant as adjuvant treatment for dermal bacterial infections}, volume={11}, journal={Drug Design Development and Therapy}, author={Draughn, G. L. and Allen, C. L. and Routh, P. A. and Stone, M. R. and Kirker, K. R. and Boegli, A. and Schuchman, R. M. and Linder, K. E. and Baynes, R. E. and James, G. and et al.}, year={2017}, pages={153–162} } @article{stephens_hubble_ernst_hoek_melander_cavanagh_melander_2016, title={Potentiation of Francisella resistance to conventional antibiotics through small molecule adjuvants}, volume={7}, DOI={10.1039/c5md00353a}, number={1}, journal={MedChemComm}, author={Stephens, M. D. and Hubble, V. B. and Ernst, R. K. and Hoek, M. L. and Melander, R. J. and Cavanagh, J. and Melander, C.}, year={2016}, pages={128–131} } @article{wahome_beauchesne_pedone_cavanagh_melander_zimba_moeller_2015, title={Augmenting anti-cancer natural products with a small molecule adjuvant}, volume={13}, number={1}, journal={Marine Drugs}, author={Wahome, P. G. and Beauchesne, K. R. and Pedone, A. C. and Cavanagh, J. and Melander, C. and Zimba, P. and Moeller, P. D. R.}, year={2015}, pages={65–75} } @article{stowe_thompson_peng_su_blackledge_draughn_coe_johannes_lapham_mackenzie_et al._2015, title={Membrane-permeabilizing activity of reverse-amide 2-aminoimidazole antibiofilm agents against Acinetobacter baumannii}, volume={12}, DOI={10.2174/1567201811666140924125740}, number={2}, journal={Current Drug Delivery}, author={Stowe, S. D. and Thompson, R. J. and Peng, L. L. and Su, Z. M. and Blackledge, M. S. and Draughn, G. L. and Coe, W. H. and Johannes, E. and Lapham, V. 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L. and Losick, R. and Cavanagh, J.}, year={2014}, pages={155–158} } @article{bobay_thompson_milton_cavanagh_2014, title={Chemical shift assignments and secondary structure prediction of the phosphorelay protein VanU from Vibrio anguillarum}, volume={8}, DOI={10.1007/s12104-013-9478-2}, number={1}, journal={Biomolecular NMR Assignments}, author={Bobay, B. G. and Thompson, R. J. and Milton, D. L. and Cavanagh, J.}, year={2014}, pages={177–179} } @article{brackett_melander_an_krishnamurthy_thompson_cavanagh_melander_2014, title={Small-molecule suppression of beta-lactam resistance in multidrug-resistant gram-negative pathogens}, volume={57}, DOI={10.1021/jm501050e}, number={17}, journal={Journal of Medicinal Chemistry}, author={Brackett, C. M. and Melander, R. J. and An, I. H. and Krishnamurthy, A. and Thompson, R. J. and Cavanagh, J. and Melander, C.}, year={2014}, pages={7450–7458} } @article{olson_tucker_bobay_soderblom_moseley_thompson_cavanagh_2014, title={Structure and DNA-binding traits of the transition state regulator AbrB}, volume={22}, DOI={10.1016/j.str.2014.08.018}, number={11}, journal={Structure (Cambridge, Mass. : 2001)}, author={Olson, A. L. and Tucker, A. T. and Bobay, B. G. and Soderblom, E. J. and Moseley, M. A. and Thompson, R. J. and Cavanagh, J.}, year={2014}, pages={1650–1656} } @article{olson_liu_tucker_goshe_cavanagh_2013, title={Chemical crosslinking and LC/MS analysis to determine protein domain orientation: Application to AbrB}, volume={431}, DOI={10.1016/j.bbrc.2012.12.124}, number={2}, journal={Biochemical and Biophysical Research Communications}, author={Olson, A. L. and Liu, F. and Tucker, A. T. and Goshe, M. B. and Cavanagh, J.}, year={2013}, pages={253–257} } @article{stowe_tucker_thompson_piper_richards_rogers_mathies_melander_cavanagh_2012, title={Evaluation of the toxicity of 2-aminoimidazole antibiofilm agents using both cellular and model organism systems}, volume={35}, DOI={10.3109/01480545.2011.614620}, number={3}, journal={Drug and Chemical Toxicology}, author={Stowe, S. D. and Tucker, A. T. and Thompson, R. and Piper, A. and Richards, J. J. and Rogers, S. A. and Mathies, L. D. and Melander, C. and Cavanagh, J.}, year={2012}, pages={310–315} } @article{olson_bobay_melander_cavanagh_2012, title={H-1, C-13, and N-15 resonance assignments and secondary structure prediction of the full-length transition state regulator AbrB from Bacillus anthracis}, volume={6}, DOI={10.1007/s12104-011-9333-2}, number={1}, journal={Biomolecular NMR Assignments}, author={Olson, A. L. and Bobay, B. G. and Melander, C. and Cavanagh, J.}, year={2012}, pages={95–98} } @article{thompson_bobay_stowe_olson_peng_su_actis_melander_cavanagh_2012, title={Identification of BfmR, a response regulator involved in biofilm development, as a target for a 2-aminoimidazole-based antibiofilm agent}, volume={51}, DOI={10.1021/bi3015289}, number={49}, journal={Biochemistry}, author={Thompson, R. J. and Bobay, B. G. and Stowe, S. D. and Olson, A. L. and Peng, L. L. and Su, Z. M. and Actis, L. A. and Melander, C. and Cavanagh, J.}, year={2012}, pages={9776–9778} } @article{bobay_stewart_tucker_thompson_varney_cavanagh_2012, title={Structural insights into the calcium-dependent interaction between calbindin-D28K and caspase-3}, volume={586}, DOI={10.1016/j.febslet.2012.08.032}, number={20}, journal={FEBS Letters}, author={Bobay, B. G. and Stewart, A. L. and Tucker, A. T. and Thompson, R. J. and Varney, K. M. and Cavanagh, J.}, year={2012}, pages={3582–3589} } @misc{stowe_richards_tucker_thompson_melander_cavanagh_2011, title={Anti-biofilm compounds derived from marine sponges}, volume={9}, number={10}, journal={Marine Drugs}, author={Stowe, S. D. and Richards, J. J. and Tucker, A. T. and Thompson, R. and Melander, C. and Cavanagh, J.}, year={2011}, pages={2010–2035} } @article{bunders_cavanagh_melander_2011, title={Flustramine inspired synthesis and biological evaluation of pyrroloindoline triazole amides as novel inhibitors of bacterial biofilms}, volume={9}, DOI={10.1039/c1ob05605k}, number={15}, journal={Organic & Biomolecular Chemistry}, author={Bunders, C. and Cavanagh, J. and Melander, C.}, year={2011}, pages={5476–5481} } @article{bunders_minvielle_worthington_ortiz_cavanagh_melander_2011, title={Intercepting bacterial indole signaling with flustramine derivatives}, volume={133}, DOI={10.1021/ja209836z}, number={50}, journal={Journal of the American Chemical Society}, author={Bunders, C. A. and Minvielle, M. J. and Worthington, R. J. and Ortiz, M. and Cavanagh, J. and Melander, C.}, year={2011}, pages={20160–20163} } @article{refaei_combs_kojetin_cavanagh_caperelli_rance_sapitro_tsang_2011, title={Observing selected domains in multi-domain proteins via sortase-mediated ligation and NMR spectroscopy}, volume={49}, DOI={10.1007/s10858-010-9464-2}, number={1}, journal={Journal of Biomolecular NMR}, author={Refaei, M. A. and Combs, A. and Kojetin, D. J. and Cavanagh, J. and Caperelli, C. and Rance, M. and Sapitro, J. and Tsang, P.}, year={2011}, pages={3–7} } @article{yang_gurgel_williams_bobay_cavanagh_muddiman_carbonell_2010, title={Binding site on human immunoglobulin G for the affinity ligand HWRGWV}, volume={23}, number={3}, journal={Journal of Molecular Recognition}, author={Yang, H. O. and Gurgel, P. V. and Williams, D. K. and Bobay, B. G. and Cavanagh, J. and Muddiman, D. C. and Carbonell, R. G.}, year={2010}, pages={271–282} } @article{bobay_thompson_hoch_cavanagh_2010, title={Long range dynamic effects of point-mutations trap a response regulator in an active conformation}, volume={584}, DOI={10.1016/j.febslet.2010.08.051}, number={19}, journal={FEBS Letters}, author={Bobay, B. G. and Thompson, R. J. and Hoch, J. A. and Cavanagh, J.}, year={2010}, pages={4203–4207} } @article{hobbs_bobay_thompson_perego_cavanagh_2010, title={NMR solution structure and DNA-binding model of the DNA-binding domain of competence protein A}, volume={398}, DOI={10.1016/j.jmb.2010.03.003}, number={2}, journal={Journal of Molecular Biology}, author={Hobbs, C. A. and Bobay, B. G. and Thompson, R. J. and Perego, M. and Cavanagh, J.}, year={2010}, pages={248–263} } @article{rogers_huigens_cavanagh_melander_2010, title={Synergistic effects between conventional antibiotics and 2-aminoimidazole-derived antibiofilm agents}, volume={54}, DOI={10.1128/aac.01418-09}, number={5}, journal={Antimicrobial Agents and Chemotherapy}, author={Rogers, S. A. and Huigens, R. W. and Cavanagh, J. and Melander, C.}, year={2010}, pages={2112–2118} } @article{richards_reyes_stowe_tucker_ballard_mathies_cavanagh_melander_2009, title={Amide isosteres of oroidin: Assessment of antibiofilm activity and C. elegans Toxicity}, volume={52}, DOI={10.1021/jm900378s}, number={15}, journal={Journal of Medicinal Chemistry}, author={Richards, J. J. and Reyes, S. and Stowe, S. D. and Tucker, A. T. and Ballard, T. E. and Mathies, L. D. and Cavanagh, J. and Melander, C.}, year={2009}, pages={4582–4585} } @article{yang_gurgel_williams_bobay_cavanagh_muddiman_carbonell_2009, title={Binding site on human immunoglobulin G for the affinity ligand HWRGWV}, ISSN={0952-3499 1099-1352}, url={http://dx.doi.org/10.1002/jmr.967}, DOI={10.1002/jmr.967}, journal={Journal of Molecular Recognition}, publisher={Wiley}, author={Yang, Haiou and Gurgel, Patrick V. and Williams, D. Keith, Jr and Bobay, Benjamin G. and Cavanagh, John and Muddiman, David C. and Carbonell, Ruben G.}, year={2009}, pages={n/a-n/a} } @article{melander_moeller_ballard_richards_huigens_cavanagh_2009, title={Evaluation of dihydrooroidin as an antifouling additive in marine paint}, volume={63}, DOI={10.1016/j.ibiod.2008.08.009}, number={4}, journal={International Biodeterioration & Biodegradation}, author={Melander, C. and Moeller, P. D. R. and Ballard, T. E. and Richards, J. J. and Huigens, R. W. and Cavanagh, J.}, year={2009}, pages={529–532} } @article{kojetin_mclaughlin_thompson_dubnau_prepiak_rance_cavanagh_2009, title={Structural and motional contributions of the Bacillus subtilis ClpC N-domain to adaptor protein interactions}, volume={387}, DOI={10.1016/j.jmb.2009.01.046}, number={3}, journal={Journal of Molecular Biology}, author={Kojetin, D. J. and McLaughlin, P. D. and Thompson, R. J. and Dubnau, D. and Prepiak, P. and Rance, M. and Cavanagh, J.}, year={2009}, pages={639–652} } @article{hobbs_deterding_perera_bobay_thompson_darden_cavanagh_tomer_2009, title={Structural characterization of the conformational change in calbindin-d-28k upon calcium binding using differential surface modification analyzed by mass spectrometry}, volume={48}, DOI={10.1021/bi900350q}, number={36}, journal={Biochemistry}, author={Hobbs, C. A. and Deterding, L. J. and Perera, L. and Bobay, B. G. and Thompson, R. J. and Darden, T. A. and Cavanagh, J. and Tomer, K. B.}, year={2009}, pages={8603–8614} } @article{szurmant_bobay_white_sullivan_thompson_hwa_hoch_cavanagh_2008, title={Co-Evolving Motions at Protein−Protein Interfaces of Two-Component Signaling Systems Identified by Covariance Analysis†}, volume={47}, ISSN={0006-2960 1520-4995}, url={http://dx.doi.org/10.1021/bi8009604}, DOI={10.1021/bi8009604}, number={30}, journal={Biochemistry}, publisher={American Chemical Society (ACS)}, author={Szurmant, Hendrik and Bobay, Benjamin G. and White, Robert A. and Sullivan, Daniel M. and Thompson, Richele J. and Hwa, Terence and Hoch, James A. and Cavanagh, John}, year={2008}, month={Jul}, pages={7782–7784} } @article{huigens_ma_gambino_moeller_basso_cavanagh_wozniak_melander_2008, title={Control of bacterial biofilms with marine alkaloid derivatives}, volume={4}, DOI={10.1039/b719989a}, number={6}, journal={Molecular BioSystems}, author={Huigens, R. W. and Ma, L. Y. and Gambino, C. and Moeller, P. D. R. and Basso, A. and Cavanagh, J. and Wozniak, D. J. and Melander, C.}, year={2008}, pages={614–621} } @article{richards_huigens iii_ballard_basso_cavanagh_melander_2008, title={Inhibition and dispersion of proteobacterial biofilms}, ISSN={1359-7345 1364-548X}, url={http://dx.doi.org/10.1039/b719802g}, DOI={10.1039/b719802g}, number={14}, journal={Chemical Communications}, publisher={Royal Society of Chemistry (RSC)}, author={Richards, Justin J. and Huigens III, Robert W. and Ballard, T. Eric and Basso, Anne and Cavanagh, John and Melander, Christian}, year={2008}, pages={1698} } @article{sullivan_bobay_kojetin_thompson_rance_strauch_cavanagh_2008, title={Insights into the nature of DNA binding of AbrB-like transcription factors}, volume={16}, DOI={10.1016/j.str.2008.08.014}, number={11}, journal={Structure (Cambridge, Mass. : 2001)}, author={Sullivan, D. M. and Bobay, B. G. and Kojetin, D. J. and Thompson, R. J. and Rance, M. and Strauch, M. A. and Cavanagh, J.}, year={2008}, pages={1702–1713} } @article{burns_bobay_basso_cavanagh_melander_2008, title={Targeting RNA with cysteine-constrained peptides}, volume={18}, DOI={10.1016/j.bmcl.2007.11.096}, number={2}, journal={Bioorganic & Medicinal Chemistry Letters}, author={Burns, V. A. and Bobay, B. G. and Basso, A. and Cavanagh, J. and Melander, C.}, year={2008}, pages={565–567} } @article{strauch_bobay_cavanagh_yao_wilson_le breton_2007, title={Abh and AbrB control of Bacillus subtilis antimicrobial gene expression}, volume={189}, DOI={10.1128/JB.01081-07}, number={21}, journal={Journal of Bacteriology}, author={Strauch, M. A. and Bobay, B. G. and Cavanagh, J. and Yao, F. and Wilson, A. and Le Breton, Y.}, year={2007}, pages={7720–7732} } @article{kojetin_mclaughlin_thompson_venters_rance_cavanagh_2007, title={NMR assignment of the N-terminal repeat domain of Bacillus subtilis ClpC}, volume={1}, DOI={10.1007/s12104-007-9046-8}, number={2}, journal={Biomolecular NMR Assignments}, author={Kojetin, D. J. and McLaughlin, P. D. and Thompson, R. J. and Venters, R. A. and Rance, M. and Cavanagh, J.}, year={2007}, pages={163–165} } @article{kordys_bobay_thompson_venters_cavanagh_2007, title={Peptide binding proclivities of calcium loaded calbindin-D28k}, volume={581}, DOI={10.1016/j.febslet.2007.09.004}, number={24}, journal={FEBS Letters}, author={Kordys, D. R. and Bobay, B. G. and Thompson, R. J. and Venters, R. A. and Cavanagh, J.}, year={2007}, pages={4778–4782} } @article{mclaughlin_bobay_regel_thompson_hoch_cavanagh_2007, title={Predominantly buried residues in the response regulator Spo0F influence specific sensor kinase recognition}, volume={581}, DOI={10.1016/j.febslet.2007.02.061}, number={7}, journal={FEBS Letters}, author={McLaughlin, P. D. and Bobay, B. G. and Regel, E. J. and Thompson, R. J. and Hoch, J. A. and Cavanagh, J.}, year={2007}, pages={1425–1429} } @article{soderblom_bobay_cavanagh_goshe_2007, title={Tandem mass spectrometry acquisition approaches to enhance identification of protein-protein interactions using low-energy collision-induced dissociative chemical crosslinking reagents}, volume={21}, DOI={10.1002/rcm.3213}, number={21}, journal={Rapid Communications in Mass Spectrometry}, author={Soderblom, E. J. and Bobay, B. G. and Cavanagh, J. and Goshe, M. B.}, year={2007}, pages={3395–3408} } @article{sharp_sullivan_cavanagh_tomer_2006, title={Measurement of multisite oxidation kinetics reveals an active site conformational change in Spo0F as a result of protein oxidation}, volume={45}, DOI={10.1021/bi060470r}, number={20}, journal={Biochemistry}, author={Sharp, J. S. and Sullivan, D. M. and Cavanagh, J. and Tomer, K. B.}, year={2006}, pages={6260–6266} } @article{bobay_mueller_thompson_murzin_venters_strauch_cavanagh_2006, title={NMR structure of AbhN and comparison with AbrBN - First insights into the DNA binding promiscuity and specificity of AbrB-like transition state regulator proteins}, volume={281}, DOI={10.1074/jbc.M601963200}, number={30}, journal={Journal of Biological Chemistry}, author={Bobay, B. G. and Mueller, G. A. and Thompson, R. J. and Murzin, A. G. and Venters, R. A. and Strauch, M. A. and Cavanagh, J.}, year={2006}, pages={21399–21409} } @article{kojetin_venters_kordys_thompson_kumar_cavanagh_2006, title={Structure, binding interface and hydrophobic transitions of Ca2+-loaded calbindin-D-28K}, volume={13}, DOI={10.1038/nsmb1112d}, number={7}, journal={Nature Structural & Molecular Biology}, author={Kojetin, D. J. and Venters, R. A. and Kordys, D. R. and Thompson, R. J. and Kumar, R. and Cavanagh, J.}, year={2006}, pages={641–647} } @article{kojetin_venters_kordys_thompson_kumar_cavanagh_2006, title={Structure, binding interface and hydrophobic transitions of Ca2+-loaded calbindin-D28K}, volume={13}, ISSN={1545-9993 1545-9985}, url={http://dx.doi.org/10.1038/nsmb1112}, DOI={10.1038/nsmb1112}, number={7}, journal={Nature Structural & Molecular Biology}, publisher={Springer Science and Business Media LLC}, author={Kojetin, Douglas J and Venters, Ronald A and Kordys, David R and Thompson, Richele J and Kumar, Rajiv and Cavanagh, John}, year={2006}, month={Jun}, pages={641–647} } @article{venters_coggins_kojetin_cavanagh_zhou_2005, title={(4,2)D projection-reconstruction experiments for protein backbone assignment: Application to human carbonic anhydrase II and calbindin D-28K}, volume={127}, DOI={10.1021/ja0509580}, number={24}, journal={Journal of the American Chemical Society}, author={Venters, R. A. and Coggins, B. E. and Kojetin, D. and Cavanagh, J. and Zhou, P.}, year={2005}, pages={8785–8795} } @article{bobay_andreeva_mueller_cavanagh_murzin_2005, title={Revised structure of the AbrB N-terminal domain unifies a diverse superfamily of putative DNA-binding proteins}, volume={579}, DOI={10.1016/j.febslet.2005.09.045}, number={25}, journal={FEBS Letters}, author={Bobay, B. G. and Andreeva, A. and Mueller, G. A. and Cavanagh, J. and Murzin, A. G.}, year={2005}, pages={5669–5674} } @article{ulrich_kojetin_bassler_cavanagh_loria_2005, title={Solution structure and dynamics of LuxU from Vibrio harveyi, a phosphotransferase protein involved in bacterial quorum sensing}, volume={347}, DOI={10.1016/j.jmb.2005.01.039}, number={2}, journal={Journal of Molecular Biology}, author={Ulrich, D. L. and Kojetin, D. and Bassler, B. L. and Cavanagh, J. and Loria, J. P.}, year={2005}, pages={297–307} } @article{kojetin_thompson_benson_naylor_waterman_davies_opperman_stephenson_hoch_cavanagh_2005, title={Structural analysis of divalent metals binding to the Bacillus subtilis response regulator Spo0F: the possibility for In vitro metalloregulation in the initiation of sporulation}, volume={18}, DOI={10.1007/s10534-005-4303-8}, number={5}, journal={Biometals}, author={Kojetin, D. J. and Thompson, R. J. and Benson, L. M. and Naylor, S. and Waterman, J. and Davies, K. G. and Opperman, C. H. and Stephenson, K. and Hoch, J. A. and Cavanagh, J.}, year={2005}, pages={449–466} } @article{bobay_benson_naylor_feeney_clark_goshe_strauch_thompson_cavanagh_2004, title={Evaluation of the DNA binding tendencies of the transition state regulator AbrB}, volume={43}, DOI={10.1021/bi048399h}, number={51}, journal={Biochemistry}, author={Bobay, B. G. and Benson, L. and Naylor, S. and Feeney, B. and Clark, A. C. and Goshe, M. B. and Strauch, M. 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