@article{ferrara_ivarsson_vallese_guiotto_colella_pecorelli_valacchi_2024, title={COMPARISON OF POLLUTANT EFFECTS ON CUTANEOUS INFLAMMASOMES ACTIVATION}, volume={218}, ISSN={["1873-4596"]}, DOI={10.1016/j.freeradbiomed.2024.04.098}, journal={FREE RADICAL BIOLOGY AND MEDICINE}, author={Ferrara, Francesca and Ivarsson, John and Vallese, Andrea and Guiotto, Anna and Colella, Sante and Pecorelli, Alessandra and Valacchi, Giuseppe}, year={2024}, month={Jun}, pages={27–27} }
 @article{ferrara_yan_pecorelli_guiotto_colella_pasqui_ivarrson_lynch_anderias_choundhary_et al._2024, title={Combined exposure to UV and PM affect skin oxinflammatory responses and it is prevented by antioxidant mix topical application: Evidences from clinical study}, volume={4}, ISSN={["1473-2165"]}, url={http://dx.doi.org/10.1111/jocd.16321}, DOI={10.1111/jocd.16321}, abstractNote={Exposure to environmental stressors like particulate matter (PM) and ultraviolet radiation (UV) induces cutaneous oxidative stress and inflammation and leads to skin barrier dysfunction and premature aging. Metals like iron or copper are abundant in PM and are known to contribute to reactive oxygen species (ROS) production.}, journal={JOURNAL OF COSMETIC DERMATOLOGY}, author={Ferrara, Francesca and Yan, Xi and Pecorelli, Alessandra and Guiotto, Anna and Colella, Sante and Pasqui, Arianna and Ivarrson, John and Lynch, Stephen and Anderias, Sara and Choundhary, Hina and et al.}, year={2024}, month={Apr} }
 @article{ivarsson_bennett_ferrara_strauch_vallase_iorizzo_pecorelli_lila_valacchi_2024, title={Gut-derived wild blueberry phenolic acid metabolites modulate extrinsic cutaneous damage}, volume={6}, ISSN={["2042-650X"]}, url={https://doi.org/10.1039/D4FO01874E}, DOI={10.1039/d4fo01874e}, abstractNote={As the first line of defense, the skin is equipped with various physiological mechanisms positioned to prevent incoming oxidative damage from numerous environmental insults. With persistent exposure to the environment, understanding ways to augment the skin defenses is paramount in protecting from premature aging. In this study, we investigated the ability of five dietary phenolic metabolites, typically found in the bloodstream after wild blueberry consumption, to successfully defend the skin from UV light exposure in a novel}, journal={FOOD & FUNCTION}, author={Ivarsson, John and Bennett, Abby and Ferrara, Francesca and Strauch, Renee and Vallase, Andrea and Iorizzo, Massimo and Pecorelli, Alessandra and Lila, Mary Ann and Valacchi, Giuseppe}, year={2024}, month={Jun} }
 @article{ivarsson_bennett_ferrara_strauch_vallese_iorizzo_pecorelli_lila_valacchi_2024, title={Gut-derived wild blueberry phenolic acid metabolites modulate extrinsic cutaneous damage (vol 15, pg 7849, 2024)}, volume={10}, ISSN={["2042-650X"]}, DOI={10.1039/d4fo90097a}, abstractNote={Correction for ‘Gut-derived wild blueberry phenolic acid metabolites modulate extrinsic cutaneous damage’ by John Ivarsson et al. , Food Funct. , 2024, 15 , 7849–7864, https://doi.org/10.1039/D4FO01874E.}, journal={FOOD & FUNCTION}, author={Ivarsson, John and Bennett, Abby and Ferrara, Francesca and Strauch, Renee and Vallese, Andrea and Iorizzo, Massimo and Pecorelli, Alessandra and Lila, Mary Ann and Valacchi, Giuseppe}, year={2024}, month={Oct} }
 @misc{ivarsson_pecorelli_lila_valacchi_2023, title={Blueberry Supplementation and Skin Health}, volume={12}, ISSN={["2076-3921"]}, url={https://www.mdpi.com/2076-3921/12/6/1261}, DOI={10.3390/antiox12061261}, abstractNote={Environmental stressors such as air pollutants, ozone, and UV radiation are among the most noxious outdoor stressors affecting human skin and leading to premature skin aging. To prevent the extrinsic aging, the skin is equipped with an effective defensive system. However, cutaneous defense mechanisms can be overwhelmed through chronic exposure to environmental pollutants. Recent studies have suggested that the topical usage of natural compounds, such as blueberries, could be a good strategy to prevent skin damage from the environment. Indeed, blueberries contain bioactive compounds found to induce an active skin response against the environmental noxious effects. In this review, results from recent studies on this topic are discussed in order to build the argument for blueberries to possibly be an effective agent for skin health. In addition, we hope to highlight the need for further research to elucidate the mechanisms behind the use of both topical application and dietary supplementation with blueberries to bolster cutaneous systems and defensive mechanisms.}, number={6}, journal={ANTIOXIDANTS}, author={Ivarsson, John and Pecorelli, Alessandra and Lila, Mary Ann and Valacchi, Giuseppe}, year={2023}, month={Jun} }
 @article{ivarsson_ferrara_vallese_guiotto_colella_pecorelli_valacchi_2023, title={Comparison of Pollutant Effects on Cutaneous Inflammasomes Activation}, volume={24}, ISSN={["1422-0067"]}, url={https://doi.org/10.3390/ijms242316674}, DOI={10.3390/ijms242316674}, abstractNote={The skin is the outermost layer of the body and, therefore, is exposed to a variety of stressors, such as environmental pollutants, known to cause oxinflammatory reactions involved in the exacerbation of several skin conditions. Today, inflammasomes are recognized as important modulators of the cutaneous inflammatory status in response to air pollutants and ultraviolet (UV) light exposure. In this study, human skin explants were exposed to the best-recognized air pollutants, such as microplastics (MP), cigarette smoke (CS), diesel engine exhaust (DEE), ozone (O3), and UV, for 1 or 4 days, to explore how each pollutant can differently modulate markers of cutaneous oxinflammation. Exposure to environmental pollutants caused an altered oxidative stress response, accompanied by increased DNA damage and signs of premature skin aging. The effect of specific pollutants being able to exert different inflammasomes pathways (NLRP1, NLRP3, NLRP6, and NLRC4) was also investigated in terms of scaffold formation and cell pyroptosis. Among all environmental pollutants, O3, MP, and UV represented the main pollutants affecting cutaneous redox homeostasis; of note, the NLRP1 and NLRP6 inflammasomes were the main ones modulated by these outdoor stressors, suggesting their role as possible molecular targets in preventing skin disorders and the inflammaging events associated with environmental pollutant exposure.}, number={23}, journal={INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES}, author={Ivarsson, John and Ferrara, Francesca and Vallese, Andrea and Guiotto, Anna and Colella, Sante and Pecorelli, Alessandra and Valacchi, Giuseppe}, year={2023}, month={Dec} }