James D Brooks

Genetic Parameter Estimates for Metabolizing Two Common Pharmaceuticals in Swine

Frontiers in Genetics, 9(FEB).

Gene co-expression network analysis identifies porcine genes associated with variation in metabolizing fenbendazole and flunixin meglumine in the liver

Scientific Reports, 7(1).

Pharmacokinetics of C-14-ortho-phenylphenol following intravenous administration in pigs

JOURNAL OF APPLIED TOXICOLOGY, 37(4), 508–512.

Skin absorption of six performance amines used in metalworking fluids

JOURNAL OF APPLIED TOXICOLOGY, 35(5), 520–528.

Development of a Mixed-Effect Pharmacokinetic Model for Vehicle Modulated In Vitro Transdermal Flux of Topically Applied Penetrants

JOURNAL OF PHARMACEUTICAL SCIENCES, 103(3), 1002–1012.

In silico models to predict dermal absorption from complex agrochemical formulations

SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 25(7), 565–588.

Prediction of formulation effects on dermal absorption of topically applied ectoparasiticides dosed in vitro on canine and porcine skin using a mixture-adjusted quantitative structure permeability relationship

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 37(5), 435–444.

Tetracycline Residues in Porcine Stomach after Administration via Drinking Water on a Swine Farm

JOURNAL OF FOOD PROTECTION, 77(1), 122–126.

The effect of breed and sex on sulfamethazine, enrofloxacin, fenbendazole and flunixin meglumine pharmacokinetic parameters in swine

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 37(6), 531–541.

Modeling the effect of experimental variables on the in vitro permeation of six model compounds across porcine skin

International Journal of Pharmaceutics, 443(1-2), 58–67.

Predicting skin permeability from complex chemical mixtures: incorporation of an expanded QSAR model

SAR and QSAR in Environmental Research, 24(9), 711–731.

Predicting skin permeability from complex vehicles

[Review of ]. ADVANCED DRUG DELIVERY REVIEWS, 65(2), 265–277.

Selection of appropriate training and validation set chemicals for modelling dermal permeability by U-optimal design

SAR and QSAR in Environmental Research, 24(2), 135–156.

Acute vascular effects of nanoparticle infusion in isolated perfused skin

Nanomedicine: Nanotechnology, Biology and Medicine, 8(4), 428–431.

Experimental factors affecting in vitro absorption of six model compounds across porcine skin

Toxicology in Vitro, 26(7), 1191–1198.

In vitro biodistribution of silver nanoparticles in isolated perfused porcine skin flaps

JOURNAL OF APPLIED TOXICOLOGY, 32(11), 913–919.

Predicting Skin Permeability from Complex Chemical Mixtures: Dependency of Quantitative Structure Permeation Relationships on Biology of Skin Model Used

TOXICOLOGICAL SCIENCES, 119(1), 224–232.

Modelling the effect of mixture components on permeation through skin

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 398(1-2), 28–32.

Riviere and Brooks pig skin flow-through [data file]

Surfactant Effects on Skin Absorption of Model Organic Chemicals: Implications for Dermal Risk Assessment Studies

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 73(11), 725–737.

Validated models for predicting skin penetration from different vehicles

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 41(5), 612–616.

Determination of the effective dermal penetration barrier pH of porcine skin

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 32(4), 407–410.

Prediction of dermal absorption from complex chemical mixtures: incorporation of vehicle effects and interactions into a QSPR framework

SAR AND QSAR IN ENVIRONMENTAL RESEARCH, Vol. 18, pp. 31–44.

A physiologically based pharmacokinetic model of organophosphate dermal absorption

TOXICOLOGICAL SCIENCES, 89(1), 188–204.

Pre-treatment effects of trichloroethylene on the dermal absorption of the biocide, triazine

TOXICOLOGY LETTERS, 159(3), 252–260.

Predicting skin permeability from complex chemical mixtures

TOXICOLOGY AND APPLIED PHARMACOLOGY, 208(2), 99–110.

Comparative mixture effects of JP-8(100) additives on the dermal absorption and disposition of jet fuel hydrocarbons in different membrane model systems

TOXICOLOGY LETTERS, 150(3), 351–365.

In vitro percutaneous absorption of nonylphenol (NP) and nonylphenol ethoxylates (NPE-4 and NPE-9) in isolated perfused skin

JOURNAL OF TOXICOLOGY-CUTANEOUS AND OCULAR TOXICOLOGY, 22(1-2), 1–11.

Percutaneous absorption of 2,6-di-tert-butyl-4-nitrophenol (DBNP) in isolated perfused porcine skin

TOXICOLOGY IN VITRO, 17(3), 289–292.

Percutaneous absorption of topical N,N-diethyl-m-toluamide (DEET): Effects of exposure variables and coadministered toxicants

Journal of Toxicology and Environmental Health. Part A, 66(2), 133–151.

Effect of chemical interactions in pentachlorophenol mixtures on skin and membrane transport

TOXICOLOGICAL SCIENCES, 69(2), 295–305.

Physicochemical determinants of linear alkylbenzene sulfonate (LAS) disposition in skin exposed to aqueous cutting fluid mixtures

TOXICOLOGY AND INDUSTRIAL HEALTH, 18(5), 237–248.

Mixture component effects on the in vitro dermal absorption of pentachlorophenol

Archives of Toxicology, 75(6), 329–334.

Mixture effects of JP-8 additives on the dermal disposition of jet fuel components

TOXICOLOGY AND APPLIED PHARMACOLOGY, 175(3), 269–281.

Use of methyl salicylate as a simulant to predict the percutaneous absorption of sulfur mustard

JOURNAL OF APPLIED TOXICOLOGY, 21(2), 91–99.

Comparative in vitro percutaneous absorption of nonylphenol and nonylphenol ethoxylates (NPE-4 and NPE-9) through human, porcine and rat skin

Toxicology and Industrial Health, 16(2), 49–57.

Dermatotoxicokinetic modeling of p-nitrophenol and its conjugation metabolite in swine following topical and intravenous administration

TOXICOLOGICAL SCIENCES, 54(2), 284–294.

Membrane transport of naphthalene and dodecane in jet fuel mixtures

Toxicology and Industrial Health, 16(6), 225–238.

Methods of assessing the percutaneous absorption of volatile chemicals in isolated perfused skin: Studies with chloropentafluorobenzene and dichlorobenzene

TOXICOLOGY METHODS, 10(4), 265–281.

Dermal Absorption and Distribution of Topically Dosed Jet Fuels Jet-A, JP-8, and JP-8(100)

Toxicology and Applied Pharmacology, 160(1), 60–75.

Pentachlorophenol dermal absorption and disposition from soil in swine: Effects of occlusion and skin microorganism inhibition

TOXICOLOGY AND APPLIED PHARMACOLOGY, 147(2), 234–246.

Percutaneous absorption of volatile chemicals

In (NTIS report AFOSR G49620-95-1-0017) (pp. 1–23).

Cutaneous metabolism of isosorbide dinitrate after transdermal administration in isolated perfused porcine skin

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 127(2), 213–217.

Quantitative percutaneous absorption and cutaneous distribution of binary mixtures of phenol and para-nitrophenol in isolated perfused porcine skin

FUNDAMENTAL AND APPLIED TOXICOLOGY, 32(2), 233–243.

The use of mechanistically defined chemical mixtures (MDCM) to assess component effects on the percutaneous absorption and cutaneous disposition of topically exposed chemicals .1. Studies with parathion mixtures in isolated perfused porcine skin

TOXICOLOGY AND APPLIED PHARMACOLOGY, 141(2), 473–486.

ENHANCING OR BLOCKING EFFECT OF FENVALERATE ON THE SUBSEQUENT PERCUTANEOUS-ABSORPTION OF PESTICIDES IN-VITRO

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 51(3), 214–219.

TOXICOKINETICS OF TOPICAL SULFUR MUSTARD PENETRATION, DISPOSITION, AND VASCULAR TOXICITY IN ISOLATED-PERFUSED PORCINE SKIN

TOXICOLOGY AND APPLIED PHARMACOLOGY, 135(1), 25–34.

Determination of physicochemical properties of phenol, p-nitrophenol, acetone and ethanol relevant to quantitating their percutaneous absorption in porcine skin

Research Communications in Chemical Pathology and Pharmacology, 83, 61–75.

Mechanisms of cutaneous vesication

In DAMD17-92-C-2071; NTIS, ADA283085 (Vol. 114, pp. 1–114). DAMD 17-92-C-2071, NTIS Report, ADA 283085.

Effect of vehicle and application site on absorption of chemicals through equine skin

Proceedings, 38th Annual Convention of the American Association of Equine Practitioners, 38, 725.

NDELA and nickel modulation of triazine disposition in skin

Baynes, R. E., Brooks, J. D., Barlow, B. M., & Riviere, J. E. Toxicology and Industrial Health, 21(9), 197–205.