Works (51)

Updated: April 11th, 2023 10:13

2018 journal article

Genetic Parameter Estimates for Metabolizing Two Common Pharmaceuticals in Swine

Frontiers in Genetics, 9(FEB).

By: J. Howard, M. Ashwell, R. Baynes, J. Brooks, J. Yeatts & C. Maltecca

author keywords: swine; pharmacogenomics; heritability; fenbendazole; flunixin meglumine
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2017 journal article

Gene co-expression network analysis identifies porcine genes associated with variation in metabolizing fenbendazole and flunixin meglumine in the liver

Scientific Reports, 7(1).

By: J. Howard, M. Ashwell n, R. Baynes, J. Brooks, J. Yeatts & C. Maltecca

Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2017 journal article

Pharmacokinetics of C-14-ortho-phenylphenol following intravenous administration in pigs

JOURNAL OF APPLIED TOXICOLOGY, 37(4), 508–512.

By: E. Nixon, J. Brooks, P. Routh, J. Chittenden* & R. Baynes

author keywords: pharmacokinetics; ortho-phenylphenol; intravenous dose; pig; biocide
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Skin absorption of six performance amines used in metalworking fluids

JOURNAL OF APPLIED TOXICOLOGY, 35(5), 520–528.

By: L. Roux*, J. Brooks, J. Yeatts & R. Baynes

author keywords: skin absorption; metalworking fluids; flow-through diffusion cell; ethanolamines; biocide
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Development of a Mixed-Effect Pharmacokinetic Model for Vehicle Modulated In Vitro Transdermal Flux of Topically Applied Penetrants

JOURNAL OF PHARMACEUTICAL SCIENCES, 103(3), 1002–1012.

By: J. Chittenden n, J. Brooks & J. Riviere

author keywords: transdermal drug delivery; skin; passive diffusion; transport; mathematical model; in vitro models; formulation vehicle; diffusion
Source: Web Of Science
Added: August 6, 2018

2014 journal article

In silico models to predict dermal absorption from complex agrochemical formulations

SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 25(7), 565–588.

By: K. Guth n, J. Riviere, J. Brooks, M. Dammann*, E. Fabian*, B. Ravenzwaay*, M. Schaefer-Korting, R. Landsiedel*

author keywords: dermal absorption; mixture; quantitative structure permeability relationship (QSPR); risk assessment; agrochemicals
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Prediction of formulation effects on dermal absorption of topically applied ectoparasiticides dosed in vitro on canine and porcine skin using a mixture-adjusted quantitative structure permeability relationship

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 37(5), 435–444.

By: J. Riviere, J. Brooks, W. Collard*, J. Deng*, G. Rose*, S. Mahabir*, D. Merritt*, A. Marchiondo*

Source: Web Of Science
Added: August 6, 2018

2014 journal article

Tetracycline Residues in Porcine Stomach after Administration via Drinking Water on a Swine Farm

JOURNAL OF FOOD PROTECTION, 77(1), 122–126.

By: D. Lindquist n, H. Wu*, S. Mason*, J. Yeatts n, J. Brooks n, B. Barlow, K. Schill n, R. Baynes

Source: Web Of Science
Added: August 6, 2018

2014 journal article

The effect of breed and sex on sulfamethazine, enrofloxacin, fenbendazole and flunixin meglumine pharmacokinetic parameters in swine

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 37(6), 531–541.

By: J. Howard n, R. Baynes, J. Brooks, J. Yeatts, B. Bellis, M. Ashwell n, P. Routh, A. O'Nan, C. Maltecca

Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Modeling the effect of experimental variables on the in vitro permeation of six model compounds across porcine skin

International Journal of Pharmaceutics, 443(1-2), 58–67.

By: D. Karadzovska n, J. Brooks & J. Riviere

author keywords: Quantitative structure-permeability; relationships (QSPeRs); Experimental variables; Mixture factor; Steady-state flux; Percutaneous absorption
Sources: Web Of Science, Crossref
Added: August 6, 2018

2013 journal article

Predicting skin permeability from complex chemical mixtures: incorporation of an expanded QSAR model

SAR and QSAR in Environmental Research, 24(9), 711–731.

By: G. Xu, J. Hughes-Oliver, J. Brooks & R. Baynes

author keywords: Abraham's LFER model; adjusted Q(LOO)(2); expanded LFER model; leave-one-solute-out; QSAR
Sources: Web Of Science, Crossref
Added: August 6, 2018

2013 review

Predicting skin permeability from complex vehicles

[Review of ]. ADVANCED DRUG DELIVERY REVIEWS, 65(2), 265–277.

By: D. Karadzovska n, J. Brooks, N. Monteiro-Riviere & J. Riviere

author keywords: Chemical mixtures; Formulations; Percutaneous/dermal absorption; Quantitative structure-permeation relationship (QSPR); QSAR; Linear free energy relationships (LFER); Mixture factor; Topical drug delivery enhancers
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Selection of appropriate training and validation set chemicals for modelling dermal permeability by U-optimal design

SAR and QSAR in Environmental Research, 24(2), 135–156.

author keywords: QSAR model; training set selection; Baynes' Rule; U-optimal design; principal component analysis (PCA); applicability domain (AD)
Sources: Web Of Science, Crossref
Added: August 6, 2018

2012 journal article

Acute vascular effects of nanoparticle infusion in isolated perfused skin

Nanomedicine: Nanotechnology, Biology and Medicine, 8(4), 428–431.

By: J. Riviere, T. Leavens, J. Brooks & N. Monteiro-Riviere

author keywords: Nanoparticles; Vascular toxicity; In vitro; Biodistribution
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2012 journal article

Experimental factors affecting in vitro absorption of six model compounds across porcine skin

Toxicology in Vitro, 26(7), 1191–1198.

By: D. Karadzovska n, J. Brooks & J. Riviere

author keywords: Dermal absorption/penetration; Diffusion cells; Saturated; Unsaturated; Finite; Infinite; Albumin
Sources: Web Of Science, Crossref
Added: August 6, 2018

2012 journal article

In vitro biodistribution of silver nanoparticles in isolated perfused porcine skin flaps

JOURNAL OF APPLIED TOXICOLOGY, 32(11), 913–919.

By: T. Leavens, N. Monteiro-Riviere, A. Inman, J. Brooks, S. Oldenburg* & J. Riviere

author keywords: silver nanoparticles; biodistribution; skin
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Predicting Skin Permeability from Complex Chemical Mixtures: Dependency of Quantitative Structure Permeation Relationships on Biology of Skin Model Used

TOXICOLOGICAL SCIENCES, 119(1), 224–232.

By: J. Riviere & J. Brooks

author keywords: chemical mixtures; percutaneous; dermal absorption; quantitative structure-activity relationships (QSAR); QSPR; skin permeability; in vitro models; pesticide risk assessment
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Modelling the effect of mixture components on permeation through skin

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 398(1-2), 28–32.

By: T. Ghafourian, E. Samaras, J. Brooks & J. Riviere

author keywords: Skin; QSAR; Formulation; Mixture; Permeation; Penetration
Source: Web Of Science
Added: August 6, 2018

2010 dataset

Riviere and Brooks pig skin flow-through [data file]

By: J. Riviere & J. Brooks

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Surfactant Effects on Skin Absorption of Model Organic Chemicals: Implications for Dermal Risk Assessment Studies

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 73(11), 725–737.

By: J. Riviere, J. Brooks, J. Yeatts & E. Koivisto

Source: Web Of Science
Added: August 6, 2018

2010 journal article

Validated models for predicting skin penetration from different vehicles

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 41(5), 612–616.

By: T. Ghafourian*, E. Samaras*, J. Brooks & J. Riviere

author keywords: Skin; Penetration; QSAR; Permeation; Formulation; Mixture
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Determination of the effective dermal penetration barrier pH of porcine skin

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 32(4), 407–410.

By: J. Riviere & J. Brooks

Source: Web Of Science
Added: August 6, 2018

2007 article

Prediction of dermal absorption from complex chemical mixtures: incorporation of vehicle effects and interactions into a QSPR framework

SAR AND QSAR IN ENVIRONMENTAL RESEARCH, Vol. 18, pp. 31–44.

By: J. Riviere & J. Brooks

author keywords: dermal absorption; chemical mixtures; QSAR; LFER
Source: Web Of Science
Added: August 6, 2018

2006 journal article

A physiologically based pharmacokinetic model of organophosphate dermal absorption

TOXICOLOGICAL SCIENCES, 89(1), 188–204.

By: D. Merwe n, J. Brooks, R. Gehring, R. Baynes, N. Monteiro-Riviere & J. Riviere

author keywords: dermal absorption; PBPK model; parathion; fenthion; methyl parathion
Sources: Web Of Science, ORCID
Added: August 6, 2018

2005 journal article

Pre-treatment effects of trichloroethylene on the dermal absorption of the biocide, triazine

TOXICOLOGY LETTERS, 159(3), 252–260.

By: R. Baynes, J. Yeatts, J. Brooks & J. Riviere

author keywords: triazine; skin; TCE; cutting fluids
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Predicting skin permeability from complex chemical mixtures

TOXICOLOGY AND APPLIED PHARMACOLOGY, 208(2), 99–110.

By: J. Riviere & J. Brooks

author keywords: QSPeR; QSAR; dermal absorption; risk assessment; chemical mixtures
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Comparative mixture effects of JP-8(100) additives on the dermal absorption and disposition of jet fuel hydrocarbons in different membrane model systems

TOXICOLOGY LETTERS, 150(3), 351–365.

By: F. Muhammad, J. Brooks & J. Riviere

author keywords: JP-8(100); mixture effects; comparative absorption; membrane models
Source: Web Of Science
Added: August 6, 2018

2003 journal article

In vitro percutaneous absorption of nonylphenol (NP) and nonylphenol ethoxylates (NPE-4 and NPE-9) in isolated perfused skin

JOURNAL OF TOXICOLOGY-CUTANEOUS AND OCULAR TOXICOLOGY, 22(1-2), 1–11.

By: N. Monteiro-Riviere, J. Van Miller*, G. Simon*, R. Joiner*, J. Brooks & J. Riviere

Sources: Web Of Science, ORCID
Added: August 6, 2018

2003 journal article

Percutaneous absorption of 2,6-di-tert-butyl-4-nitrophenol (DBNP) in isolated perfused porcine skin

TOXICOLOGY IN VITRO, 17(3), 289–292.

By: A. Inman, K. Still*, W. Jederberg*, R. Carpenter*, J. Riviere, J. Brooks, N. Monteiro-Riviere

author keywords: 2,6-di-tert-butyl-4-nitrophenol; skin absorption; porcine skin; dermal exposure
Sources: Web Of Science, ORCID
Added: August 6, 2018

2003 journal article

Percutaneous absorption of topical N,N-diethyl-m-toluamide (DEET): Effects of exposure variables and coadministered toxicants

Journal of Toxicology and Environmental Health. Part A, 66(2), 133–151.

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2002 journal article

Effect of chemical interactions in pentachlorophenol mixtures on skin and membrane transport

TOXICOLOGICAL SCIENCES, 69(2), 295–305.

By: R. Baynes, J. Brooks, M. Mumtaz & J. Riviere

author keywords: pentachorophenol; mixtures; interactions; skin; absorption; surfactants; vehicle
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Physicochemical determinants of linear alkylbenzene sulfonate (LAS) disposition in skin exposed to aqueous cutting fluid mixtures

TOXICOLOGY AND INDUSTRIAL HEALTH, 18(5), 237–248.

By: R. Baynes, J. Brooks, B. Barlow & J. Riviere

author keywords: cutting fluids; LAS; mixtures; physicochemical interactions; skin
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Mixture component effects on the in vitro dermal absorption of pentachlorophenol

Archives of Toxicology, 75(6), 329–334.

By: J. Riviere, G. Qiao n, R. Baynes, J. Brooks & M. Mumtaz*

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Mixture effects of JP-8 additives on the dermal disposition of jet fuel components

TOXICOLOGY AND APPLIED PHARMACOLOGY, 175(3), 269–281.

By: R. Baynes, J. Brooks, K. Budsaba, C. Smith n & J. Riviere

author keywords: jet fuels; mixtures; skin; interactions; absorption
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Use of methyl salicylate as a simulant to predict the percutaneous absorption of sulfur mustard

JOURNAL OF APPLIED TOXICOLOGY, 21(2), 91–99.

By: J. Riviere, C. Smith, K. Budsaba, J. Brooks, E. Olajos*, H. Salem*, N. Monteiro-Riviere

Sources: Web Of Science, ORCID
Added: August 6, 2018

2000 journal article

Comparative in vitro percutaneous absorption of nonylphenol and nonylphenol ethoxylates (NPE-4 and NPE-9) through human, porcine and rat skin

Toxicology and Industrial Health, 16(2), 49–57.

By: N. Monteiro-Riviere, J. Miller, G. Simon, R. Joiner, J. Brooks & J. Riviere

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2000 journal article

Dermatotoxicokinetic modeling of p-nitrophenol and its conjugation metabolite in swine following topical and intravenous administration

TOXICOLOGICAL SCIENCES, 54(2), 284–294.

By: G. Qiao*, S. Chang, J. Brooks & J. Riviere

author keywords: p-nitrophenol (PNP); toxicokinetics; skin absorption; metabolism; pig
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Membrane transport of naphthalene and dodecane in jet fuel mixtures

Toxicology and Industrial Health, 16(6), 225–238.

By: R. Baynes, J. Brooks & J. Riviere

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Methods of assessing the percutaneous absorption of volatile chemicals in isolated perfused skin: Studies with chloropentafluorobenzene and dichlorobenzene

TOXICOLOGY METHODS, 10(4), 265–281.

By: J. Riviere, J. Brooks & G. Qiao*

author keywords: chloropentafluorobenzene; dermal absorption; dichlorobenzene; volatile chemicals
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Dermal Absorption and Distribution of Topically Dosed Jet Fuels Jet-A, JP-8, and JP-8(100)

Toxicology and Applied Pharmacology, 160(1), 60–75.

author keywords: jet fuel; naphthalene; dodecane; hexadecane; percutaneous/dermal absorption; skin
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

1997 journal article

Pentachlorophenol dermal absorption and disposition from soil in swine: Effects of occlusion and skin microorganism inhibition

TOXICOLOGY AND APPLIED PHARMACOLOGY, 147(2), 234–246.

By: G. Qiao, J. Brooks & J. Riviere

Source: Web Of Science
Added: August 6, 2018

1997 report

Percutaneous absorption of volatile chemicals

In (NTIS report AFOSR G49620-95-1-0017) (pp. 1–23).

By: J. Riviere, J. Brooks, G. Qiao & N. Monteiro-Riviere

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

1996 journal article

Cutaneous metabolism of isosorbide dinitrate after transdermal administration in isolated perfused porcine skin

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 127(2), 213–217.

By: J. Riviere, J. Brooks, P. Williams n, E. McGown* & M. Francoeur*

author keywords: isosorbide dinitrate; isosorbide mononitrate; cutaneous metabolism; IPPSF; skin flap; percutaneous delivery device
Source: Web Of Science
Added: August 6, 2018

1996 journal article

Quantitative percutaneous absorption and cutaneous distribution of binary mixtures of phenol and para-nitrophenol in isolated perfused porcine skin

FUNDAMENTAL AND APPLIED TOXICOLOGY, 32(2), 233–243.

By: J. Brooks & J. Riviere

Source: Web Of Science
Added: August 6, 2018

1996 journal article

The use of mechanistically defined chemical mixtures (MDCM) to assess component effects on the percutaneous absorption and cutaneous disposition of topically exposed chemicals .1. Studies with parathion mixtures in isolated perfused porcine skin

TOXICOLOGY AND APPLIED PHARMACOLOGY, 141(2), 473–486.

By: G. Qiao, J. Brooks, R. Baynes n, N. MonteiroRiviere n, P. Williams n & J. Riviere

Sources: Web Of Science, ORCID
Added: August 6, 2018

1995 journal article

ENHANCING OR BLOCKING EFFECT OF FENVALERATE ON THE SUBSEQUENT PERCUTANEOUS-ABSORPTION OF PESTICIDES IN-VITRO

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 51(3), 214–219.

By: S. Chang, J. Brooks, N. Monteiroriviere n & J. Riviere

Sources: Web Of Science, ORCID
Added: August 6, 2018

1995 journal article

TOXICOKINETICS OF TOPICAL SULFUR MUSTARD PENETRATION, DISPOSITION, AND VASCULAR TOXICITY IN ISOLATED-PERFUSED PORCINE SKIN

TOXICOLOGY AND APPLIED PHARMACOLOGY, 135(1), 25–34.

By: J. Riviere, J. Brooks, P. Williams n & N. Monteiroriviere n

Sources: Web Of Science, ORCID
Added: August 6, 2018

1994 journal article

Determination of physicochemical properties of phenol, p-nitrophenol, acetone and ethanol relevant to quantitating their percutaneous absorption in porcine skin

Research Communications in Chemical Pathology and Pharmacology, 83, 61–75.

By: P. William, J. Brooks, A. Inman, N. Monteiro-Riviere & J. Riviere

Source: NC State University Libraries
Added: August 6, 2018

1994 report

Mechanisms of cutaneous vesication

In DAMD17-92-C-2071; NTIS, ADA283085 (Vol. 114, pp. 1–114). DAMD 17-92-C-2071, NTIS Report, ADA 283085.

By: N. Monteiro-Riviere, J. Zhang, A. Inman, J. Brooks & J. Riviere

Source: NC State University Libraries
Added: August 6, 2018

1992 conference paper

Effect of vehicle and application site on absorption of chemicals through equine skin

Proceedings, 38th Annual Convention of the American Association of Equine Practitioners, 38, 725.

By: D. Bristol, J. Riviere, N. Monteiro-Riviere, J. Brooks & R. Rogers

Source: NC State University Libraries
Added: August 6, 2018

journal article

NDELA and nickel modulation of triazine disposition in skin

Baynes, R. E., Brooks, J. D., Barlow, B. M., & Riviere, J. E. Toxicology and Industrial Health, 21(9), 197–205.

By: R. Baynes, J. Brooks, B. Barlow & J. Riviere

Source: NC State University Libraries
Added: August 6, 2018