James Brooks Howard, J. T., Ashwell, M. S., Baynes, R. E., Brooks, J. D., Yeatts, J. L., & Maltecca, C. (2018). Genetic Parameter Estimates for Metabolizing Two Common Pharmaceuticals in Swine. Frontiers in Genetics, 9(FEB). https://doi.org/10.3389/fgene.2018.00040 Howard, J. T., Ashwell, M. S., Baynes, R. E., Brooks, J. D., Yeatts, J. L., & Maltecca, C. (2017). Gene co-expression network analysis identifies porcine genes associated with variation in metabolizing fenbendazole and flunixin meglumine in the liver. Scientific Reports, 7(1). https://doi.org/10.1038/s41598-017-01526-5 Nixon, E., Brooks, J. D., Routh, P. A., Chittenden, J. T., & Baynes, R. E. (2017). Pharmacokinetics of C-14-ortho-phenylphenol following intravenous administration in pigs. JOURNAL OF APPLIED TOXICOLOGY, 37(4), 508–512. https://doi.org/10.1002/jat.3380 Roux, L. N., Brooks, J. D., Yeatts, J. L., & Baynes, R. E. (2015). Skin absorption of six performance amines used in metalworking fluids. JOURNAL OF APPLIED TOXICOLOGY, 35(5), 520–528. https://doi.org/10.1002/jat.3056 Chittenden, J. T., Brooks, J. D., & Riviere, J. E. (2014). Development of a Mixed-Effect Pharmacokinetic Model for Vehicle Modulated In Vitro Transdermal Flux of Topically Applied Penetrants. JOURNAL OF PHARMACEUTICAL SCIENCES, 103(3), 1002–1012. https://doi.org/10.1002/jps.23862 Guth, K., Riviere, J. E., Brooks, J. D., Dammann, M., Fabian, E., Ravenzwaay, B., … Landsiedel, R. (2014). In silico models to predict dermal absorption from complex agrochemical formulations. SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 25(7), 565–588. https://doi.org/10.1080/1062936x.2014.919358 Riviere, J. E., Brooks, J. D., Collard, W. T., Deng, J., Rose, G., Mahabir, S. P., … Marchiondo, A. A. (2014). Prediction of formulation effects on dermal absorption of topically applied ectoparasiticides dosed in vitro on canine and porcine skin using a mixture-adjusted quantitative structure permeability relationship. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 37(5), 435–444. https://doi.org/10.1111/jvp.12121 Lindquist, D., Wu, H., Mason, S., Yeatts, J., Brooks, J., Barlow, B., … Baynes, R. (2014). Tetracycline Residues in Porcine Stomach after Administration via Drinking Water on a Swine Farm. JOURNAL OF FOOD PROTECTION, 77(1), 122–126. https://doi.org/10.4315/0362-028x.jfp-13-199 Howard, J. T., Baynes, R. E., Brooks, J. D., Yeatts, J. L., Bellis, B., Ashwell, M. S., … Maltecca, C. (2014). The effect of breed and sex on sulfamethazine, enrofloxacin, fenbendazole and flunixin meglumine pharmacokinetic parameters in swine. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 37(6), 531–541. https://doi.org/10.1111/jvp.12128 Karadzovska, D., Brooks, J. D., & Riviere, J. E. (2013). Modeling the effect of experimental variables on the in vitro permeation of six model compounds across porcine skin. International Journal of Pharmaceutics, 443(1-2), 58–67. https://doi.org/10.1016/j.ijpharm.2013.01.002 Xu, G., Hughes-Oliver, J. M., Brooks, J. D., & Baynes, R. E. (2013). Predicting skin permeability from complex chemical mixtures: incorporation of an expanded QSAR model. SAR and QSAR in Environmental Research, 24(9), 711–731. https://doi.org/10.1080/1062936x.2013.792875 Karadzovska, D., Brooks, J. D., Monteiro-Riviere, N. A., & Riviere, J. E. (2013). [Review of Predicting skin permeability from complex vehicles]. ADVANCED DRUG DELIVERY REVIEWS, 65(2), 265–277. https://doi.org/10.1016/j.addr.2012.01.019 Xu, G., Hughes-Oliver, J. M., Brooks, J. D., Yeatts, J. L., & Baynes, R. E. (2013). Selection of appropriate training and validation set chemicals for modelling dermal permeability by U-optimal design. SAR and QSAR in Environmental Research, 24(2), 135–156. https://doi.org/10.1080/1062936x.2012.742458 Riviere, J. E., Leavens, T. L., Brooks, J. D., & Monteiro-Riviere, N. A. (2012). Acute vascular effects of nanoparticle infusion in isolated perfused skin. Nanomedicine: Nanotechnology, Biology and Medicine, 8(4), 428–431. https://doi.org/10.1016/j.nano.2012.02.016 Karadzovska, D., Brooks, J. D., & Riviere, J. E. (2012). Experimental factors affecting in vitro absorption of six model compounds across porcine skin. Toxicology in Vitro, 26(7), 1191–1198. https://doi.org/10.1016/j.tiv.2012.06.009 Leavens, T. L., Monteiro-Riviere, N. A., Inman, A. O., Brooks, J. D., Oldenburg, S. J., & Riviere, J. E. (2012). In vitro biodistribution of silver nanoparticles in isolated perfused porcine skin flaps. JOURNAL OF APPLIED TOXICOLOGY, 32(11), 913–919. https://doi.org/10.1002/jat.2750 Riviere, J. E., & Brooks, J. D. (2011). Predicting Skin Permeability from Complex Chemical Mixtures: Dependency of Quantitative Structure Permeation Relationships on Biology of Skin Model Used. TOXICOLOGICAL SCIENCES, 119(1), 224–232. https://doi.org/10.1093/toxsci/kfq317 Ghafourian, T., Samaras, E. G., Brooks, J. D., & Riviere, J. E. (2010). Modelling the effect of mixture components on permeation through skin. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 398(1-2), 28–32. https://doi.org/10.1016/j.ijpharm.2010.07.014 Riviere, J. L., & Brooks, J. D. (2010). Riviere and Brooks pig skin flow-through [data file]. Riviere, J. E., Brooks, J. D., Yeatts, J. L., & Koivisto, E. L. (2010). Surfactant Effects on Skin Absorption of Model Organic Chemicals: Implications for Dermal Risk Assessment Studies. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 73(11), 725–737. https://doi.org/10.1080/15287391003614026 Ghafourian, T., Samaras, E. G., Brooks, J. D., & Riviere, J. E. (2010). Validated models for predicting skin penetration from different vehicles. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 41(5), 612–616. https://doi.org/10.1016/j.ejps.2010.08.014 Riviere, J. E., & Brooks, J. D. (2009). Determination of the effective dermal penetration barrier pH of porcine skin. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 32(4), 407–410. https://doi.org/10.1111/j.1365-2885.2008.01055.x Riviere, J. E., & Brooks, J. D. (2007). Prediction of dermal absorption from complex chemical mixtures: incorporation of vehicle effects and interactions into a QSPR framework. SAR AND QSAR IN ENVIRONMENTAL RESEARCH, Vol. 18, pp. 31–44. https://doi.org/10.1080/10629360601033598 Merwe, D., Brooks, J. D., Gehring, R., Baynes, R. E., Monteiro-Riviere, N. A., & Riviere, J. E. (2006). A physiologically based pharmacokinetic model of organophosphate dermal absorption. TOXICOLOGICAL SCIENCES, 89(1), 188–204. https://doi.org/10.1093/toxsci/kfj014 Baynes, R. E., Yeatts, J. L., Brooks, J. D., & Riviere, J. E. (2005). Pre-treatment effects of trichloroethylene on the dermal absorption of the biocide, triazine. TOXICOLOGY LETTERS, 159(3), 252–260. https://doi.org/10.1016/j.toxlet.2005.05.012 Riviere, J. E., & Brooks, J. D. (2005). Predicting skin permeability from complex chemical mixtures. TOXICOLOGY AND APPLIED PHARMACOLOGY, 208(2), 99–110. https://doi.org/10.1016/j.taap.2005.02.016 Muhammad, F., Brooks, J. D., & Riviere, J. E. (2004). Comparative mixture effects of JP-8(100) additives on the dermal absorption and disposition of jet fuel hydrocarbons in different membrane model systems. TOXICOLOGY LETTERS, 150(3), 351–365. https://doi.org/10.1016/j.toxlet.2004.02.012 Monteiro-Riviere, N. A., Van Miller, J. P., Simon, G. S., Joiner, R. L., Brooks, J., & Riviere, J. E. (2003). In vitro percutaneous absorption of nonylphenol (NP) and nonylphenol ethoxylates (NPE-4 and NPE-9) in isolated perfused skin. JOURNAL OF TOXICOLOGY-CUTANEOUS AND OCULAR TOXICOLOGY, 22(1-2), 1–11. https://doi.org/10.1081/CUS-120019325 Inman, A. O., Still, K. R., Jederberg, W. W., Carpenter, R. L., Riviere, J. E., Brooks, J. D., & Monteiro-Riviere, N. A. (2003). Percutaneous absorption of 2,6-di-tert-butyl-4-nitrophenol (DBNP) in isolated perfused porcine skin. TOXICOLOGY IN VITRO, 17(3), 289–292. https://doi.org/10.1016/S0887-2333(03)00015-8 Riviere, J. E., Baynes, R. E., Brooks, J. D., Yeatts, J. L., & Monteiro-Riviere, N. A. (2003). Percutaneous absorption of topical N,N-diethyl-m-toluamide (DEET): Effects of exposure variables and coadministered toxicants. Journal of Toxicology and Environmental Health. Part A, 66(2), 133–151. https://doi.org/10.1080/15287390390155796 Baynes, R. E., Brooks, J. D., Mumtaz, M., & Riviere, J. E. (2002). Effect of chemical interactions in pentachlorophenol mixtures on skin and membrane transport. TOXICOLOGICAL SCIENCES, 69(2), 295–305. https://doi.org/10.1093/toxsci/69.2.295 Baynes, R. E., Brooks, J. D., Barlow, B. M., & Riviere, J. E. (2002). Physicochemical determinants of linear alkylbenzene sulfonate (LAS) disposition in skin exposed to aqueous cutting fluid mixtures. TOXICOLOGY AND INDUSTRIAL HEALTH, 18(5), 237–248. https://doi.org/10.1191/0748233702th147oa Riviere, J. E., Qiao, G. L., Baynes, R. E., Brooks, J. D., & Mumtaz, M. (2001). Mixture component effects on the in vitro dermal absorption of pentachlorophenol. Archives of Toxicology, 75(6), 329–334. https://doi.org/10.1007/s002040100242 Baynes, R. E., Brooks, J. D., Budsaba, K., Smith, C. E., & Riviere, J. E. (2001). Mixture effects of JP-8 additives on the dermal disposition of jet fuel components. TOXICOLOGY AND APPLIED PHARMACOLOGY, 175(3), 269–281. https://doi.org/10.1006/taap.2001.9259 Riviere, J. E., Smith, C. E., Budsaba, K., Brooks, J. D., Olajos, E. J., Salem, H., & Monteiro-Riviere, N. A. (2001). Use of methyl salicylate as a simulant to predict the percutaneous absorption of sulfur mustard. JOURNAL OF APPLIED TOXICOLOGY, 21(2), 91–99. https://doi.org/10.1002/jat.718 Monteiro-Riviere, N. A., Miller, J. P. V., Simon, G., Joiner, R. L., Brooks, J. D., & Riviere, J. E. (2000). Comparative in vitro percutaneous absorption of nonylphenol and nonylphenol ethoxylates (NPE-4 and NPE-9) through human, porcine and rat skin. Toxicology and Industrial Health, 16(2), 49–57. https://doi.org/10.1191/074823300678827654 Qiao, G. L., Chang, S. K., Brooks, J. D., & Riviere, J. E. (2000). Dermatotoxicokinetic modeling of p-nitrophenol and its conjugation metabolite in swine following topical and intravenous administration. TOXICOLOGICAL SCIENCES, 54(2), 284–294. https://doi.org/10.1093/toxsci/54.2.284 Baynes, R. E., Brooks, J. D., & Riviere, J. E. (2000). Membrane transport of naphthalene and dodecane in jet fuel mixtures. Toxicology and Industrial Health, 16(6), 225–238. https://doi.org/10.1191/074823300678839264 Riviere, J. E., Brooks, J. D., & Qiao, G. L. (2000). Methods of assessing the percutaneous absorption of volatile chemicals in isolated perfused skin: Studies with chloropentafluorobenzene and dichlorobenzene. TOXICOLOGY METHODS, 10(4), 265–281. https://doi.org/10.1080/105172300750048746 Riviere, J. E., Brooks, J. D., Monteiro-Riviere, N. A., Budsaba, K., & Smith, C. E. (1999). Dermal Absorption and Distribution of Topically Dosed Jet Fuels Jet-A, JP-8, and JP-8(100). Toxicology and Applied Pharmacology, 160(1), 60–75. https://doi.org/10.1006/taap.1999.8744 Qiao, G. L., Brooks, J. D., & Riviere, J. E. (1997). Pentachlorophenol dermal absorption and disposition from soil in swine: Effects of occlusion and skin microorganism inhibition. TOXICOLOGY AND APPLIED PHARMACOLOGY, 147(2), 234–246. https://doi.org/10.1006/taap.1997.8288 Riviere, J. E., Brooks, J. D., Qiao, G. L., & Monteiro-Riviere, N. A. (1997). Percutaneous absorption of volatile chemicals. In (NTIS report AFOSR G49620-95-1-0017) (pp. 1–23). https://doi.org/10.21236/ada332910 Riviere, J. E., Brooks, J. D., Williams, P. L., McGown, E., & Francoeur, M. L. (1996). Cutaneous metabolism of isosorbide dinitrate after transdermal administration in isolated perfused porcine skin. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 127(2), 213–217. https://doi.org/10.1016/0378-5173(95)04213-X Brooks, J. D., & Riviere, J. E. (1996). Quantitative percutaneous absorption and cutaneous distribution of binary mixtures of phenol and para-nitrophenol in isolated perfused porcine skin. FUNDAMENTAL AND APPLIED TOXICOLOGY, 32(2), 233–243. https://doi.org/10.1006/faat.1996.0126 Qiao, G. L., Brooks, J. D., Baynes, R. E., MonteiroRiviere, N. A., Williams, P. L., & Riviere, J. E. (1996). The use of mechanistically defined chemical mixtures (MDCM) to assess component effects on the percutaneous absorption and cutaneous disposition of topically exposed chemicals .1. Studies with parathion mixtures in isolated perfused porcine skin. TOXICOLOGY AND APPLIED PHARMACOLOGY, 141(2), 473–486. https://doi.org/10.1006/taap.1996.0313 CHANG, S. K., BROOKS, J. D., MONTEIRORIVIERE, N. A., & RIVIERE, J. E. (1995). ENHANCING OR BLOCKING EFFECT OF FENVALERATE ON THE SUBSEQUENT PERCUTANEOUS-ABSORPTION OF PESTICIDES IN-VITRO. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 51(3), 214–219. https://doi.org/10.1006/pest.1995.1021 RIVIERE, J. E., BROOKS, J. D., WILLIAMS, P. L., & MONTEIRORIVIERE, N. A. (1995). TOXICOKINETICS OF TOPICAL SULFUR MUSTARD PENETRATION, DISPOSITION, AND VASCULAR TOXICITY IN ISOLATED-PERFUSED PORCINE SKIN. TOXICOLOGY AND APPLIED PHARMACOLOGY, 135(1), 25–34. https://doi.org/10.1006/taap.1995.1205 William, P. L., Brooks, J. D., Inman, A. O., Monteiro-Riviere, N. A., & Riviere, J. E. (1994). Determination of physicochemical properties of phenol, p-nitrophenol, acetone and ethanol relevant to quantitating their percutaneous absorption in porcine skin. Research Communications in Chemical Pathology and Pharmacology, 83, 61–75. Monteiro-Riviere, N. A., Zhang, J. Z., Inman, A. O., Brooks, J. D., & Riviere, J. E. (1994). Mechanisms of cutaneous vesication. In DAMD17-92-C-2071; NTIS, ADA283085 (Vol. 114, pp. 1–114). DAMD 17-92-C-2071, NTIS Report, ADA 283085. Bristol, D. G., Riviere, J. E., Monteiro-Riviere, N. A., Brooks, J. D., & Rogers, R. A. (1992). Effect of vehicle and application site on absorption of chemicals through equine skin. Proceedings, 38th Annual Convention of the American Association of Equine Practitioners, 38, 725. Baynes, R. E., Brooks, J. D., Barlow, B. M., & Riviere, J. E. NDELA and nickel modulation of triazine disposition in skin. Toxicology and Industrial Health, 21(9), 197–205.