@article{clerkin_varkey_sudweeks_2023, title={Five Nonprofit Leadership Challenges A Proposed Typology of Common Issues that Nonprofit Leaders Face}, volume={13}, ISSN={["2157-0604"]}, DOI={10.18666/JNEL-2022-10802}, abstractNote={Nonprofit leaders face many challenges and would benefit from a typology that helps highlight the core issues organizations experience. The Nonprofit Studies Minor at North Carolina State University identified five nonprofit leadership challenges, through a combination of practitioner experience and academic research, that could serve as a typology. The challenges identified are earning the public trust; aligning mission, methods, and resources; capitalizing on issues associated with diversity; balancing individual interests and the common good; and moving beyond charity to systemic change. This research revisits the academic literature to assess whether these challenges encompass the research agenda of nonprofit and voluntary action academic studies. Using qualitative content analysis, we examined abstracts from three major nonprofit journals from 2005-2017. Results indicate that the five leadership challenges were present in the abstracts of all three journals. Chi-squared analysis showed statistically significant differences in the presence of leadership challenges based on journal, location of the study, and unit of analysis. Validating this typology strengthens the Institute’s efforts and inform research and practice throughout the field.}, number={2}, journal={JOURNAL OF NONPROFIT EDUCATION AND LEADERSHIP}, author={Clerkin, Richard M. and Varkey, Sapna and Sudweeks, Jayce}, year={2023}, pages={31–58} } @article{sudweeks_hollingsworth_blondel_campbell_dhole_eisemann_edwards_godwin_howald_oh_et al._2019, title={Locally Fixed Alleles: A method to localize gene drive to island populations}, volume={9}, ISSN={["2045-2322"]}, DOI={10.1038/s41598-019-51994-0}, abstractNote={AbstractInvasive species pose a major threat to biodiversity on islands. While successes have been achieved using traditional removal methods, such as toxicants aimed at rodents, these approaches have limitations and various off-target effects on island ecosystems. Gene drive technologies designed to eliminate a population provide an alternative approach, but the potential for drive-bearing individuals to escape from the target release area and impact populations elsewhere is a major concern. Here we propose the “Locally Fixed Alleles” approach as a novel means for localizing elimination by a drive to an island population that exhibits significant genetic isolation from neighboring populations. Our approach is based on the assumption that in small island populations of rodents, genetic drift will lead to alleles at multiple genomic loci becoming fixed. In contrast, multiple alleles are likely to be maintained in larger populations on mainlands. Utilizing the high degree of genetic specificity achievable using homing drives, for example based on the CRISPR/Cas9 system, our approach aims at employing one or more locally fixed alleles as the target for a gene drive on a particular island. Using mathematical modeling, we explore the feasibility of this approach and the degree of localization that can be achieved. We show that across a wide range of parameter values, escape of the drive to a neighboring population in which the target allele is not fixed will at most lead to modest transient suppression of the non-target population. While the main focus of this paper is on elimination of a rodent pest from an island, we also discuss the utility of the locally fixed allele approach for the goals of population suppression or population replacement. Our analysis also provides a threshold condition for the ability of a gene drive to invade a partially resistant population.}, journal={SCIENTIFIC REPORTS}, author={Sudweeks, Jaye and Hollingsworth, Brandon and Blondel, Dimitri V and Campbell, Karl J. and Dhole, Sumit and Eisemann, John D. and Edwards, Owain and Godwin, John and Howald, Gregg R. and Oh, Kevin P. and et al.}, year={2019}, month={Nov} } @article{delborne_kuzma_gould_frow_leitschuh_sudweeks_2018, title={‘Mapping research and governance needs for gene drives’}, volume={5}, ISSN={2329-9460 2329-9037}, url={http://dx.doi.org/10.1080/23299460.2017.1419413}, DOI={10.1080/23299460.2017.1419413}, abstractNote={‘Mapping research and governance needs for gene drives’ Jason Delborne, Jennifer Kuzma, Fred Gould, Emma Frow, Caroline Leitschuh & Jayce Sudweeks To cite this article: Jason Delborne, Jennifer Kuzma, Fred Gould, Emma Frow, Caroline Leitschuh & Jayce Sudweeks (2018): ‘Mapping research and governance needs for gene drives’, Journal of Responsible Innovation, DOI: 10.1080/23299460.2017.1419413 To link to this article: https://doi.org/10.1080/23299460.2017.1419413}, number={sup1}, journal={Journal of Responsible Innovation}, publisher={Informa UK Limited}, author={Delborne, Jason and Kuzma, Jennifer and Gould, Fred and Frow, Emma and Leitschuh, Caroline and Sudweeks, Jayce}, year={2018}, month={Jan}, pages={S4–S12} } @article{baltzegar_barnes_elsensohn_gutzmann_jones_king_sudweeks_2018, title={Anticipating complexity in the deployment of gene drive insects in agriculture}, volume={5}, ISSN={["2329-9037"]}, DOI={10.1080/23299460.2017.1407910}, abstractNote={Insects cause substantial losses to agricultural crops each year and require intensive management approaches. Genetic pest management has emerged as a viable, non-chemical alternative for managing insect pests. The development of engineered gene drives for agricultural use is promising, though unproven, and has the potential to impact farmers as well as broader socio-ecological systems in several ways. Drawing on lessons from the deployment of other pest control technologies, this paper considers how insects containing gene drives could intersect with some of the complexities that characterize agricultural systems. Gene drives are being developed in a landscape of pest management shaped by past and current approaches, experiences, regulations, public opinion, and pest invasions. Because gene drive insects may spread well beyond their release area, stakeholder groups at different spatial scales need to be engaged in decisions about their deployment. This new paradigm both complicates and offers great promise for future pest management efforts.}, journal={JOURNAL OF RESPONSIBLE INNOVATION}, author={Baltzegar, Jennifer and Barnes, Jessica Cavin and Elsensohn, Johanna E. and Gutzmann, Nicole and Jones, Michael S. and King, Sheron and Sudweeks, Jayce}, year={2018}, pages={S81–S97} }