Works (8)

Updated: July 27th, 2023 21:18

2021 journal article

Secondary bile acid ursodeoxycholic acid alters weight, the gut microbiota, and the bile acid pool in conventional mice

PLOS ONE, 16(2).

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Body Weight / drug effects; Cecum / microbiology; Feces / microbiology; Female; Gastrointestinal Microbiome / drug effects; Ileum / microbiology; Male; Metabolome / drug effects; Mice, Inbred C57BL; Receptors, Cytoplasmic and Nuclear / metabolism; Receptors, G-Protein-Coupled / metabolism; Ursodeoxycholic Acid / administration & dosage; Ursodeoxycholic Acid / pharmacology; Weight Loss / drug effects
Source: Web Of Science
Added: March 22, 2021

2020 journal article

Clostridioides difficile carriage in animals and the associated changes in the host fecal microbiota

ANAEROBE, 66.

By: R. Thanissery n, M. McLaren nโ€‰, A. Rivera n, A. Reed n, N. Betrapally n, T. Burdette n, J. Winston n, M. Jacob n, B. Callahan nโ€‰, C. Theriot n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: C. difficile; C. hiranonis; Microbiome; Ribotype; Antibiotic resistance; Animal; Canine; Equine; Feline
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Bacterial Toxins / genetics; Bacterial Toxins / metabolism; Bacterial Typing Techniques; Cats; Chlorocebus aethiops; Clostridioides difficile / classification; Clostridioides difficile / drug effects; Clostridioides difficile / physiology; Clostridium Infections / epidemiology; Clostridium Infections / microbiology; Clostridium Infections / veterinary; Coculture Techniques; Dogs; Feces / microbiology; Female; Gastrointestinal Microbiome; Horses; Hospitals, Animal; Host-Pathogen Interactions; Male; Microbial Interactions; Microbial Sensitivity Tests; North Carolina; Polymerase Chain Reaction; Prevalence; RNA, Ribosomal, 16S; Ribotyping; Risk Factors; Tertiary Healthcare; Vero Cells
Sources: Web Of Science, ORCID
Added: January 11, 2021

2020 review

Diversification of host bile acids by members of the gut microbiota

[Review of ]. GUT MICROBES, 11(2), 158โ€“171.

By: J. Winston n & C. Theriot n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: C. difficile; bile acids; gut microbiota; ursodeoxycholic acid (UDCA); FXR
MeSH headings : Animals; Bacteria / metabolism; Bile Acids and Salts / biosynthesis; Bile Acids and Salts / metabolism; Cholesterol / metabolism; Clostridioides difficile / pathogenicity; Gastrointestinal Microbiome / drug effects; Gastrointestinal Microbiome / physiology; Hepatocytes / metabolism; Humans; Lipid Metabolism; Microbiota / drug effects; Receptors, Cytoplasmic and Nuclear / metabolism; Ursodeoxycholic Acid / pharmacology
Source: Web Of Science
Added: March 30, 2020

2020 journal article

Ursodeoxycholic Acid (UDCA) Mitigates the Host Inflammatory Response during Clostridioides difficile Infection by Altering Gut Bile Acids

INFECTION AND IMMUNITY, 88(6).

By: J. Winston n, A. Rivera n, J. Caiโ€‰*, R. Thanissery n, S. Montgomery*, A. Pattersonโ€‰*, C. Theriot n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: C. difficile; FXR; UDCA; bile acids; inflammation; microbiome; ursodiol
MeSH headings : Animals; Bile Acids and Salts / metabolism; Biomarkers; Clostridioides difficile / drug effects; Clostridium Infections / drug therapy; Clostridium Infections / genetics; Clostridium Infections / metabolism; Clostridium Infections / microbiology; Computational Biology / methods; Dose-Response Relationship, Drug; Fibroblast Growth Factors / metabolism; Fragile X Mental Retardation Protein / metabolism; Gastrointestinal Microbiome / drug effects; Gene Expression Profiling; Host-Pathogen Interactions / drug effects; Host-Pathogen Interactions / genetics; Humans; Life Cycle Stages; Mice; Signal Transduction; Transcriptome; Ursodeoxycholic Acid / pharmacology; Ursodeoxycholic Acid / physiology
Source: Web Of Science
Added: June 15, 2020

2017 article

Inhibition of spore germination, growth, and toxin activity of clinically relevant C-difficile strains by gut microbiota derived secondary bile acids

Thanissery, R., Winston, J. A., & Theriot, C. M. (2017, June). ANAEROBE, Vol. 45, pp. 86โ€“100.

By: R. Thanissery n, J. Winston n & C. Theriot n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: C. difficile; Bile acids; Gut microbiota; Metabolome; Germination; Growth; Toxin
MeSH headings : Animals; Anti-Bacterial Agents / metabolism; Antibiosis; Bacterial Toxins / metabolism; Bile Acids and Salts / metabolism; Clostridioides difficile / drug effects; Clostridioides difficile / growth & development; Gastrointestinal Microbiome; Gastrointestinal Tract / microbiology; Humans; Mice; Spores, Bacterial / drug effects; Spores, Bacterial / growth & development
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, (118).

By: J. Winston n, R. Thanissery n, S. Montgomery & C. Theriot n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Infection; Issue 118; Clostridium difficile; mouse model; antibiotic; colonization; cytotoxicity; histology; inflammation; Vero cells
MeSH headings : Animals; Anti-Bacterial Agents; Cefoperazone / pharmacology; Clostridioides difficile / drug effects; Disease Models, Animal; Humans; Mice; Mice, Inbred C57BL
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Cyniclomyces guttulatus Infection in Dogs: 19 Cases (2006-2013)

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 52(1), 42โ€“51.

By: J. Winston n, I. Piperisova n, J. Neel nโ€‰ & J. Gookin nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: J. Winston n, I. Piperisova n, J. Neel nโ€‰ & J. Gookin nโ€‰

Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Impact of microbial derived secondary bile acids on colonization resistance against Clostridium difficile in the gastrointestinal tract

ANAEROBE, 41, 44โ€“50.

By: J. Winston n & C. Theriot n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Clostridium difficile; Secondary bile acids; Colonization resistance; Gut microbiota; Antibiotics
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / therapeutic use; Bile Acids and Salts / pharmacology; Bile Acids and Salts / physiology; Clostridioides difficile / drug effects; Clostridioides difficile / physiology; Disease Susceptibility; Drug Resistance, Neoplasm; Enterocolitis, Pseudomembranous / drug therapy; Enterocolitis, Pseudomembranous / microbiology; Gastrointestinal Microbiome; Gastrointestinal Tract / microbiology; Humans
Source: Web Of Science
Added: August 6, 2018

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