Julien F. Ayroles

Works (15)

Updated: July 5th, 2023 15:50

2010 journal article

Individual variation in pheromone response correlates with reproductive traits and brain gene expression in worker honey bees

PLoS One, 5(2).

By: S. Kocher, J. Ayroles, E. Stone & C. Grozinger

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Alcohol Sensitivity in Drosophila: Translational Potential of Systems Genetics

GENETICS, 183(2), 733–745.

By: T. Morozova*, J. Ayroles*, K. Jordan*, L. Duncan*, M. Carbone*, R. Lyman*, E. Stone  n, D. Govindaraju ...

MeSH headings : Alcohol Drinking / genetics; Animals; Cluster Analysis; Drosophila Proteins / genetics; Drosophila Proteins / metabolism; Drosophila melanogaster / genetics; Ethanol / pharmacology; Female; Gene Expression Regulation / drug effects; Gene Regulatory Networks; Genes, Insect / genetics; Genetic Variation; Genome, Insect / genetics; Genome-Wide Association Study / methods; Genotype; Humans; Inbreeding; Malate Dehydrogenase / genetics; Malate Dehydrogenase / metabolism; Male; Phenotype; Polymorphism, Single Nucleotide; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction
TL;DR: Seven intronic single nucleotide polymorphisms of the Malic Enzyme 1 (ME1) gene that are associated with cocktail drinking in 1687 individuals of the Framingham Offspring cohort are identified, implicating that variation in levels of cytoplasmic malic enzyme may contribute to variation in alcohol consumption. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Co-regulated transcriptional networks contribute to natural genetic variation in Drosophila sleep

NATURE GENETICS, 41(3), 371–375.

By: S. Harbison n, M. Carbone n, J. Ayroles n, E. Stone  n, R. Lyman n & T. Mackay n

MeSH headings : Animals; Animals, Genetically Modified; Animals, Inbred Strains; Drosophila / genetics; Drosophila Proteins / genetics; Female; Gene Expression Regulation / physiology; Gene Regulatory Networks / physiology; Genes, Insect; Genetic Variation / physiology; Genome, Insect; Genome-Wide Association Study / veterinary; Male; Models, Biological; Molecular Sequence Data; Polymorphism, Genetic; Sleep / genetics
TL;DR: It is independently confirmed that molecular polymorphisms in Catsup (Catecholamines up) are associated with variation in sleep and that P-element mutations in four candidate genes affect sleep and gene expression and co-regulated gene expression using P- element mutants are confirmed. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Modulated Modularity Clustering as an Exploratory Tool for Functional Genomic Inference

PLOS GENETICS, 5(5).

By: E. Stone n & J. Ayroles n

MeSH headings : Animals; Cluster Analysis; Computer Simulation; Data Interpretation, Statistical; Databases, Genetic; Drosophila melanogaster / genetics; Gene Expression Profiling / statistics & numerical data; Genetic Techniques; Genomics / statistics & numerical data; Humans; Lymphocytes / immunology; Lymphocytes / metabolism; Models, Genetic; Multigene Family; Systems Biology
TL;DR: A new objective-based clustering method, modulated modularity clustering (MMC), which modulates the connection strengths of edges in a weighted graph to maximize an objective function (called modularity) that quantifies community structure in graphical data. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2009 journal article

Systems genetics of complex traits in Drosophila melanogaster

NATURE GENETICS, 41(3), 299–307.

By: J. Ayroles n, M. Carbone n, E. Stone  n, K. Jordan n, R. Lyman n, M. Magwire n, S. Rollmann n, L. Duncan n ...

MeSH headings : Amino Acid Sequence; Animals; Animals, Inbred Strains; Base Sequence; Chromosome Mapping; Drosophila melanogaster / genetics; Female; Gene Regulatory Networks / physiology; Genetic Variation / physiology; Genetics, Population / methods; Male; Molecular Sequence Data; Phenotype; Quantitative Trait, Heritable; RNA, Messenger / analysis; RNA, Messenger / genetics; RNA, Messenger / metabolism; Sequence Homology, Amino Acid; Tissue Distribution
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15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2006 review

Analysis of variance of microarray data

[Review of ]. Dna microarrays, part b: databases and statistics, 411, 214-. San Diego: Elsevier Academic Press Inc.

By: J. Ayroles & G. Gibson

Source: NC State University Libraries
Added: August 6, 2018

journal article

A transcriptional network associated with natural variation in Drosophila aggressive behavior

Edwards, A. C., Ayroles, J. F., Stone, E. A., Carbone, M. A., Lyman, R. F., & Mackay, T. F. C. Genome Biology, 10(7).

By: A. Edwards, J. Ayroles, E. Stone, M. Carbone, R. Lyman & T. Mackay

Source: NC State University Libraries
Added: August 6, 2018

journal article

Epistasis dominates the genetic architecture of Drosophila quantitative traits

Huang, W., Richards, S., Carbone, M. A., Zhu, D. H., Anholt, R. R. H., Ayroles, J. F., … Muzny, D. Proceedings of the National Academy of Sciences of the United States of America, 109(39), 15553–15559.

By: W. Huang, S. Richards, M. Carbone, D. Zhu, R. Anholt, J. Ayroles, L. Duncan, K. Jordan ...

Source: NC State University Libraries
Added: August 6, 2018

journal article

Functional genome annotation of Drosophila seminal fluid proteins using transcriptional genetic networks

Ayroles, J. F., Laflamme, B. A., Stone, E. A., Wolfner, M. F., & Mackay, T. F. C. Genetical Research, 93(6), 387–395.

By: J. Ayroles, B. Laflamme, E. Stone, M. Wolfner & T. Mackay

Source: NC State University Libraries
Added: August 6, 2018

journal article

Overexpression of myocilin in the Drosophila eye activates the unfolded protein response: Implications for glaucoma

Carbone, M. A., Ayroles, J. F., Yamamoto, A., Morozova, T. V., West, S. A., Magwire, M. M., … Anholt, R. R. H. PLoS One, 4(1).

By: M. Carbone, J. Ayroles, A. Yamamoto, T. Morozova, S. West, M. Magwire, T. Mackay, R. Anholt

Source: NC State University Libraries
Added: August 6, 2018

journal article

Systems genetics analysis of body weight and energy metabolism traits in Drosophila melanogaster

Jumbo-Lucioni, P., Ayroles, J. F., Chambers, M. M., Jordan, K. W., Leips, J., Mackay, T. F. C., … Luca, M. BMC Genomics, 11.

By: P. Jumbo-Lucioni, J. Ayroles, M. Chambers, K. Jordan, J. Leips, T. Mackay, De, M. Luca

Source: NC State University Libraries
Added: August 6, 2018

journal article

The Drosophila melanogaster genetic reference panel

Mackay, T. F. C., Richards, S., Stone, E. A., Barbadilla, A., Ayroles, J. F., Zhu, D. H., … Carbone, M. A. Nature, 482(7384), 173–178.

By: T. Mackay, S. Richards, E. Stone, A. Barbadilla, J. Ayroles, D. Zhu, S. Casillas, Y. Han ...

Source: NC State University Libraries
Added: August 6, 2018

journal article

The genetic basis of natural variation in mushroom body size in Drosophila melanogaster

Zwarts, L., Vanden Broeck, L., Cappuyns, E., Ayroles, J. F., Magwire, M. M., Vulsteke, V., … Callaerts, P. Nature Communications, 6.

By: L. Zwarts, L. Vanden Broeck, E. Cappuyns, J. Ayroles, M. Magwire, V. Vulsteke, J. Clements, T. Mackay, P. Callaerts

Source: NC State University Libraries
Added: August 6, 2018

review

The genetics of quantitative traits: Challenges and prospects

Mackay, T. F. C., Stone, E. A., & Ayroles, J. F. [Review of ]. Nature Reviews. Genetics, 10(8), 565–577.

By: T. Mackay, E. Stone & J. Ayroles

Source: NC State University Libraries
Added: August 6, 2018

journal article

Using whole-genome sequence data to predict quantitative trait phenotypes in Drosophila melanogaster

Ober, U., Ayroles, J. F., Stone, E. A., Richards, S., Zhu, D. H., Gibbs, R. A., … Simianer, H. PLoS Genetics, 8(5).

By: U. Ober, J. Ayroles, E. Stone, S. Richards, D. Zhu, R. Gibbs, C. Stricker, D. Gianola ...

Source: NC State University Libraries
Added: August 6, 2018

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