Works (5)

Updated: April 22nd, 2024 07:45

2024 article

Charge Protection in Electret Air Filtration Nonwoven Materials

Lavoie, J., Rojas, O. J., Khan, S. A., & Shim, E. (2024, April 9). ADVANCED MATERIALS TECHNOLOGIES, Vol. 4.

By: J. Lavoie n, O. Rojas n, S. Khan n & E. Shim n

author keywords: air filtration; charge retention; electret filter; melt additive; nonwovens
Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 15, 2024

2024 journal article

Novel multimodal cation-exchange membrane for the purification of a single-chain variable fragment from Pichia pastoris supernatant

JOURNAL OF CHROMATOGRAPHY A, 1718.

By: D. Pham*, M. Linova*, W. Smith n, H. Brown n, D. Elhanafi n, J. Fan n, J. Lavoie n, J. Woodley*, R. Carbonell n

author keywords: Multimodal ligand; Membrane chromatography; Nonwoven membranes; Single-chain variable fragment (scFv); Pichia pastoris fermentation
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: April 8, 2024

2023 article

Advances in high-throughput, high-capacity nonwoven membranes for chromatography in downstream processing: A review

Lavoie, J., Fan, J., Pourdeyhimi, B., Boi, C., & Carbonell, R. G. (2023, May 31). BIOTECHNOLOGY AND BIOENGINEERING, Vol. 5.

By: J. Lavoie n, J. Fan n, B. Pourdeyhimi n, C. Boi & R. Carbonell n

author keywords: downstream purification; fibrous systems; membrane adsorbers; membrane chromatography; nonwovens; product capture and polishing
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: June 19, 2023

2021 journal article

Iminodiacetic Acid (IDA) Cation-Exchange Nonwoven Membranes for Efficient Capture of Antibodies and Antibody Fragments

MEMBRANES, 11(7).

By: J. Fan n, C. Boi, S. Lemma n, J. Lavoie n & R. Carbonell n

author keywords: membrane adsorbers; membrane chromatography; nonwoven membranes; cation-exchange; UV grafting; monoclonal antibodies (mAbs); single-chain variable fragment (scFv)
TL;DR: There is significant evidence that this weak cation-exchange nonwoven fabric platform might be a suitable alternative to packed resin chromatography for low-cost, higher productivity manufacturing of therapeutic mAbs and antibody fragments. (via Semantic Scholar)
Source: Web Of Science
Added: August 2, 2021

2021 journal article

Removal of host cell proteins from cell culture fluids by weak partitioning chromatography using peptide-based adsorbents

SEPARATION AND PURIFICATION TECHNOLOGY, 257.

By: R. Lavoie n, W. Chu n, J. Lavoie n, Z. Hetzler n, T. Williams n, R. Carbonell n, S. Menegatti n

Contributors: R. Lavoie n, W. Chu n, J. Lavoie n, Z. Hetzler n, T. Williams n, R. Carbonell n, S. Menegatti n

author keywords: Host cell proteins; Monoclonal antibodies; Flow-through chromatography; Weak partitioning mode; Polishing; Proteomics; Peptide ligands
TL;DR: Proteomic analysis of the effluents demonstrated that 6HP+4MP-Toyopearl adsorbent removes HCPs known for their immunogenicity or IgG co-elution or degradation, demonstrating the potential of these peptide-based resins as HCP scrubbers in mAb purification processes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 11, 2021

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