Jeffrey Hymes

Works (3)

Updated: July 23rd, 2023 21:14

2016 article

Functional Analysis of an S-Layer-Associated Fibronectin-Binding Protein in Lactobacillus acidophilus NCFM

Hymes, J. P., Johnson, B. R., Barrangou, R., & Klaenhammer, T. R. (2016, February 27). (E. G. Dudley, Ed.). Applied and Environmental Microbiology, Vol. 82, pp. 2676–2685.

By: J. Hymes n, B. Johnson n, R. Barrangou n  & T. Klaenhammer n

Ed(s): E. Dudley

MeSH headings : Bacterial Adhesion / physiology; Bacterial Proteins / chemistry; Bacterial Proteins / metabolism; Fibronectins / metabolism; Intestines / microbiology; Lactobacillus acidophilus / chemistry; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / metabolism; Membrane Glycoproteins / metabolism; Mutation; Phylogeny; Protein Binding
topics (OpenAlex): Probiotics and Fermented Foods; Antimicrobial Peptides and Activities; Glycosylation and Glycoproteins Research
TL;DR: To investigate the functional role of LBA0191 (designated FbpB) in L. acidophilus NCFM, an fbpB-deficient strain was constructed and a mutant with a deletion of fBPB lost the ability to adhere to mucin and fibronectin in vitro. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2016 article

Stuck in the Middle: Fibronectin-Binding Proteins in Gram-Positive Bacteria

Hymes, J. P., & Klaenhammer, T. R. (2016, September 22). Frontiers in Microbiology.

By: J. Hymes n & T. Klaenhammer n

author keywords: fibronectin; Lactobacillus; Acidophifus; lactobacilli; streptococci
topics (OpenAlex): Streptococcal Infections and Treatments; Biochemical and Structural Characterization; Antimicrobial Resistance in Staphylococcus
TL;DR: The interaction between human fibronectin and bacterial adhesins is described by highlighting the FnBPs of Gram-positive pathogens and commensals by providing an overview of the occurrence and diversity of FnBBP with a focus on the model pathogenic organisms in which FnBPS are most characterized. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2015 article

Conserved S-Layer-Associated Proteins Revealed by Exoproteomic Survey of S-Layer-Forming Lactobacilli

Johnson, B. R., Hymes, J., Sanozky-Dawes, R., Henriksen, E. D. C., Barrangou, R., & Klaenhammer, T. R. (2015, October 17). (H. Nojiri, Ed.). Applied and Environmental Microbiology, Vol. 82, pp. 134–145.

By: B. Johnson n, J. Hymes n, R. Sanozky-Dawes n, E. Henriksen n, R. Barrangou n  & T. Klaenhammer n

Ed(s): H. Nojiri

MeSH headings : Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Lactobacillus / chemistry; Lactobacillus / classification; Lactobacillus / genetics; Lactobacillus / metabolism; Lactobacillus acidophilus / chemistry; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / metabolism; Membrane Glycoproteins / chemistry; Membrane Glycoproteins / genetics; Membrane Glycoproteins / metabolism; Molecular Sequence Data; Phylogeny; Proteomics
topics (OpenAlex): Probiotics and Fermented Foods; Microbial Metabolites in Food Biotechnology; Glycosylation and Glycoproteins Research
TL;DR: Proteomic complexity and differences in the cell surface properties between S-layer- and non-S- layer-forming lactobacilli reveal the potential for SLAPs to mediate intimate probiotic interactions and signaling with the host intestinal mucosa. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

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