John J. Sakon

Works (3)

Updated: July 13th, 2023 21:15

2020 article

How Membrane Geometry Regulates Protein Sorting Independently of Mean Curvature

Larsen, J. B., Rosholm, K. R., Kennard, C., Pedersen, S. L., Munch, H. K., Tkach, V., … Stamou, D. (2020, June 23). ACS Central Science, Vol. 6, pp. 1159–1168.

By: J. Larsen *, K. Rosholm *, C. Kennard *, S. Pedersen *, H. Munch *, V. Tkach*, J. Sakon n, T. Bjørnholm * ...

topics (OpenAlex): Lipid Membrane Structure and Behavior; Cellular transport and secretion; Biochemical and Structural Characterization; Bacterial Genetics and Biotechnology; Glycosylation and Glycoproteins Research
TL;DR: The results reveal that distinct membrane geometries have specific physicochemical properties and thus establish a ubiquitous mechanistic foundation for unravelling the conserved correlations between biological function and membrane polymorphism. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 24, 2020

2011 journal article

DNA methylation profiling in nanochannels

Biomicrofluidics, 5(3).

By: S. Lim , A. Karpusenko, J. Sakon, J. Hook, T. Lamar & R. Riehn 

Source: NC State University Libraries
Added: August 6, 2018

2010 article

Detecting the conformation of individual proteins in live cells

Sakon, J. J., & Weninger, K. R. (2010, January 31). Nature Methods, Vol. 7, pp. 203–256.

By: J. Sakon n & K. Weninger n 

MeSH headings : Cells, Cultured; Fluorescence Resonance Energy Transfer; Humans; Membrane Fusion; Protein Conformation; Protein Folding; SNARE Proteins / chemistry; Synaptosomal-Associated Protein 25
topics (OpenAlex): Advanced Fluorescence Microscopy Techniques; Cellular transport and secretion; Lipid Membrane Structure and Behavior
TL;DR: Single-molecule fluorescence resonance energy transfer with single-particle tracking in live cells to detect the in vivo conformation of individual proteins shows the potential of this method to reveal dynamic interactions within cells. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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