Jacob Kaufman

College of Engineering

2020 journal article

Algorithmically Controlled Electroporation: A Technique for Closed Loop Temperature Regulated Pulsed Electric Field Cancer Ablation


By: R. Petrella n, C. Fesmire n, J. Kaufman n, N. Topasna n & M. Sano n

author keywords: Temperature control; Temperature measurement; Temperature sensors; Electric fields; Protocols; Temperature dependence; In vitro; Non-thermal high frequency irreversible electroporation; electro-thermal therapy; pulsed electric field; bioelectric; electroporation
MeSH headings : Electricity; Electroporation; Humans; Models, Theoretical; Neoplasms; Temperature
TL;DR: The results of this study indicate ablative outcomes due to exposure to pulses on the order of one microsecond may be thermally mediated and dependent on local tissue temperatures. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 10, 2020

2020 journal article

Electro-thermal therapy: Microsecond duration pulsed electric field tissue ablation with dynamic temperature control algorithms


By: M. Sano n, R. Petrella n, J. Kaufman n, C. Fesmire n, L. Xing*, D. Gerber*, C. Fogle n

author keywords: Cancer therapy; Irreversible electroporation; Thermal ablation; H-FIRE; NK-IRE
MeSH headings : Algorithms; Electrodes; Electroporation; Liver / surgery; Temperature
TL;DR: The results establish ETT as a viable method for hepatic tumor treatment with ablation profiles equivalent to other energy based techniques and the single applicator and multi-applicator approaches demonstrated may enable the treatment of complex tumor geometries. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: July 13, 2020

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