@article{brody_loree_sampson_mensinkai_coffman_mueller_askin_hamill_wilson_mcateer_et al._2023, title={Searching for evidence in public health emergencies: a white paper of best practices}, url={https://doi.org/10.5195/jmla.2023.1530}, DOI={10.5195/jmla.2023.1530}, abstractNote={Objectives: Information professionals have supported medical providers, administrators and decision-makers, and guideline creators in the COVID-19 response. Searching COVID-19 literature presented new challenges, including the volume and heterogeneity of literature and the proliferation of new information sources, and exposed existing issues in metadata and publishing. An expert panel developed best practices, including recommendations, elaborations, and examples, for searching during public health emergencies. Methods: Project directors and advisors developed core elements from experience and literature. Experts, identified by affiliation with evidence synthesis groups, COVID-19 search experience, and nomination, responded to an online survey to reach consensus on core elements. Expert participants provided written responses to guiding questions. A synthesis of responses provided the foundation for focus group discussions. A writing group then drafted the best practices into a statement. Experts reviewed the statement prior to dissemination. Results: Twelve information professionals contributed to best practice recommendations on six elements: core resources, search strategies, publication types, transparency and reproducibility, collaboration, and conducting research. Underlying principles across recommendations include timeliness, openness, balance, preparedness, and responsiveness.  Conclusions: The authors and experts anticipate the recommendations for searching for evidence during public health emergencies will help information specialists, librarians, evidence synthesis groups, researchers, and decision-makers respond to future public health emergencies, including but not limited to disease outbreaks. The recommendations complement existing guidance by addressing concerns specific to emergency response. The statement is intended as a living document. Future revisions should solicit input from a broader community and reflect conclusions of meta-research on COVID-19 and health emergencies.}, journal={Journal of the Medical Library Association}, author={Brody, Stacy and Loree, Sara and Sampson, Margaret and Mensinkai, Shaila and Coffman, Jennifer and Mueller, Mark and Askin, Nicole and Hamill, Cheryl and Wilson, Emma and McAteer, Mary Beth and et al.}, year={2023}, month={Apr} } @article{williams_jung_coffman_lutz_2018, title={Pore Engineering for Enhanced Mass Transport in Encapsulin Nanocompartments}, volume={7}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-85056646233&partnerID=MN8TOARS}, DOI={10.1021/acssynbio.8b00295}, abstractNote={Encapsulins are robust and engineerable proteins that form hollow, nanosized, icosahedral capsids, making them attractive vehicles for drug delivery, scaffolds for synthetic bionanoreactors, and artificial organelles. A major limitation of native encapsulins is the small size of pores in the protein shell. At 3 Å diameter, these pores impose significant restrictions on the molecular weight and diffusion rate of potential substrates. By redesigning the pore-forming loop region in encapsulin from Thermotoga maritima, we successfully enlarged pore diameter up to an estimated 11 Å and increased mass transport rates by 7-fold as measured by lanthanide ion diffusion assay. Our study demonstrates the high tolerance of encapsulin for protein engineering and has created a set of novel, functionally improved scaffolds for applications as bionanoreactors.}, number={11}, journal={ACS Synthetic Biology}, author={Williams, E.M. and Jung, S.M. and Coffman, J.L. and Lutz, S.}, year={2018}, pages={2514–2517} }