Junlang Li

College of Engineering

Works (16)

Updated: August 31st, 2023 05:02

2023 journal article

An inhaled bioadhesive hydrogel to shield non-human primates from SARS-CoV-2 infection

Nature Materials, 2.

By: X. Mei n, J. Li n, Z. Wang n, D. Zhu n, K. Huang n, S. Hu n, K. Popowski n, K. Cheng

Sources: Web Of Science, ORCID, Crossref
Added: March 6, 2023

2023 journal article

Comparison of extruded cell nanovesicles and exosomes in their molecular cargos and regenerative potentials

NANO RESEARCH, 16(5), 7248–7259.

By: X. Wang n, S. Hu n, D. Zhu n, J. Li n, K. Cheng n & G. Liu*

author keywords: nanovesicles (NVs); exosomes; cardiac repair; mesenchymal stem cells (MSCs); extracellular vesicles (EVs); myocardial infarction (Ml)
Sources: Web Of Science, ORCID
Added: August 28, 2023

2023 journal article

Intrapericardial long non-coding RNA–Tcf21 antisense RNA inducing demethylation administration promotes cardiac repair

European Heart Journal, 44(19), 1748–1760.

By: D. Zhu n, S. Liu n, K. Huang n, J. Li n, X. Mei n, Z. Li n, K. Cheng n

author keywords: Myocardial infarction; Adverse remodelling; Mesenchymal stem cell; EVs; lncRNA; Tcf21
MeSH headings : Mice; Animals; Swine; RNA, Long Noncoding / genetics; RNA, Long Noncoding / metabolism; RNA, Antisense / genetics; RNA, Antisense / metabolism; Ventricular Remodeling; Myocardial Infarction / genetics; Myocardial Infarction / therapy; Myocardial Infarction / metabolism; Fibrosis; Demethylation
Sources: Web Of Science, ORCID, Crossref
Added: April 4, 2023

2022 journal article

Inhalable dry powder mRNA vaccines based on extracellular vesicles

Matter, 5(9), 2960–2974.

By: K. Popowski n, A. Moatti n, G. Scull n, D. Silkstone n, H. Lutz n, B. López de Juan Abad n, A. George n, E. Belcher n ...

Sources: Web Of Science, ORCID, Crossref
Added: October 17, 2022

2022 journal article

Intrapericardial Exosome Therapy Dampens Cardiac Injury via Activating Foxo3

CIRCULATION RESEARCH, 131(10), E135–E150.

By: D. Zhu n, S. Liu n, K. Huang n, Z. Wang n, S. Hu n, J. Li n, Z. Li n, K. Cheng n

author keywords: exosomes; immunomodulation; mesesnchymal stem cell; myocardial infarction; regulatory T cell
MeSH headings : Humans; Exosomes / metabolism; Forkhead Box Protein O3 / genetics; Forkhead Box Protein O3 / metabolism; Mesenchymal Stem Cells / metabolism; Myocardial Infarction / pathology; Proto-Oncogene Proteins c-akt / metabolism; Signal Transduction; Heart Injuries / metabolism
Sources: Web Of Science, ORCID
Added: November 14, 2022

2022 journal article

Intrapericardial hydrogel injection generates high cell retention and augments therapeutic effects of mesenchymal stem cells in myocardial infarction

CHEMICAL ENGINEERING JOURNAL, 427.

By: J. Li n, Y. Lv*, D. Zhu n, X. Mei n, K. Huang n, X. Wang n, Z. Li n, S. Zhang n ...

author keywords: Mesenchymal stem cells; Hydrogel; Myocardial infarction; Intrapericardial; Intramyocardial
Sources: Web Of Science, ORCID
Added: January 3, 2022

2022 journal article

Nanoparticles functionalized with stem cell secretome and CXCR4-overexpressing endothelial membrane for targeted osteoporosis therapy

JOURNAL OF NANOBIOTECHNOLOGY, 20(1).

By: C. Zhang n, W. Zhang*, D. Zhu n, Z. Li n, Z. Wang n, J. Li n, X. Mei n, W. Xu*, K. Cheng n, B. Zhong*

author keywords: Osteoporosis; CXCR4; Secretome; Mesenchymal stem cells; Bone targeting; Nanoparticles
MeSH headings : Animals; Cell Membrane / chemistry; Cell Membrane / metabolism; Disease Models, Animal; Endothelial Cells / chemistry; Endothelial Cells / metabolism; Mesenchymal Stem Cells / chemistry; Mesenchymal Stem Cells / metabolism; Nanoparticle Drug Delivery System; Nanoparticles; Osteoporosis / metabolism; Rats; Receptors, CXCR4 / metabolism; Secretome / metabolism
Sources: Web Of Science, ORCID
Added: January 24, 2022

2021 journal article

A Minimally Invasive Exosome Spray Repairs Heart after Myocardial Infarction

ACS NANO, 15(7), 11099–11111.

By: J. Yao*, K. Huang n, D. Zhu n, T. Chen*, Y. Jiang*, J. Zhang*, L. Mi*, H. Xuan ...

author keywords: MSC; exosome; spray; myocardial infarction; heart repair
MeSH headings : Mice; Swine; Animals; Exosomes; Myocardial Infarction / therapy; Mesenchymal Stem Cells; Heart; Disease Models, Animal
Sources: Web Of Science, ORCID
Added: August 23, 2021

2021 journal article

A fluid-powered refillable origami heart pouch for minimally invasive delivery of cell therapies in rats and pigs

MED, 2(11), 1253-+.

By: X. Mei n, D. Zhu n, J. Li n, K. Huang n, S. Hu n, Z. Li n, B. Abad n, K. Cheng n

MeSH headings : Animals; Cell- and Tissue-Based Therapy; Heart; Mesenchymal Stem Cell Transplantation / methods; Mesenchymal Stem Cells; Myocardial Infarction / surgery; Rats; Swine
Sources: Web Of Science, ORCID
Added: November 3, 2021

2021 journal article

A stem cell-derived ovarian regenerative patch restores ovarian function and rescues fertility in rats with primary ovarian insufficiency

THERANOSTICS, 11(18), 8894–8908.

By: S. Zhang*, D. Zhu*, Z. Li*, K. Huang*, S. Hu*, H. Lutz*, M. Xie*, X. Mei* ...

author keywords: primary ovarian insufficiency; ovarian regenerative patch; regenerative medicine; mesenchymal stem cells; acellular therapy; fertility
MeSH headings : Animals; Apoptosis; Cell-Derived Microparticles / metabolism; Disease Models, Animal; Female; Hydrogels / pharmacology; Infertility, Female / therapy; Mesenchymal Stem Cell Transplantation / methods; Mesenchymal Stem Cells / metabolism; Ovary / pathology; Primary Ovarian Insufficiency / therapy; Rats; Rats, Sprague-Dawley; Regenerative Medicine / methods; Secretome; Stem Cells / metabolism; Tissue Scaffolds
Sources: Web Of Science, ORCID
Added: October 12, 2021

2021 journal article

A trifunctional contraceptive gel enhances the safety and quality of sexual intercourse

BIOACTIVE MATERIALS, 6(6), 1777–1788.

By: M. Xie n, J. Li n, S. Zhang n, D. Zhu n, X. Mei n, Z. Wang n, X. Cheng n, Z. Li n, S. Wang*, K. Cheng n

author keywords: Contraceptive; Hydrogel; Anti-viral; Libido; Erectile function
Sources: Web Of Science, ORCID
Added: March 6, 2021

2021 review

Advances in biomaterials and regenerative medicine for primary ovarian insufficiency therapy

[Review of ]. BIOACTIVE MATERIALS, 6(7), 1957–1972.

By: S. Zhang n, D. Zhu n, X. Mei n, Z. Li n, J. Li n, M. Xie n, H. Xie, S. Wang*, K. Cheng n

author keywords: Stem cells; Primary ovarian insufficiency; Cell therapy; Biomaterials
Sources: Web Of Science, ORCID
Added: March 6, 2021

2021 review

All Roads Lead to Rome (the Heart): Cell Retention and Outcomes From Various Delivery Routes of Cell Therapy Products to the Heart

[Review of ]. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 10(8).

By: J. Li n, S. Hu n, D. Zhu n, K. Huang n, X. Mei n, B. Abad n, K. Cheng

author keywords: cardiac repair; cell delivery; intracoronary; intramyocardial; intrapericardial; intravenous; retention rate
MeSH headings : Animals; Cell- and Tissue-Based Therapy / methods; Heart Diseases / therapy; Humans; Injections
Sources: Web Of Science, ORCID
Added: June 10, 2021

2021 journal article

Extruded Mesenchymal Stem Cell Nanovesicles Are Equally Potent to Natural Extracellular Vesicles in Cardiac Repair

ACS APPLIED MATERIALS & INTERFACES, 13(47), 55767–55779.

By: X. Wang*, S. Hu n, J. Li n, D. Zhu n, Z. Wang n, J. Cores n, K. Cheng n, G. Liu*, K. Huang

author keywords: extrusion; nanovesicles; extracellular vesicles; mesenchymal stem cell; ischemia reperfusion injury
MeSH headings : Animals; Disease Models, Animal; Endothelial Cells / drug effects; Endothelial Cells / pathology; Extracellular Vesicles / chemistry; Fibroblasts / drug effects; Fibroblasts / pathology; Mesenchymal Stem Cells / chemistry; Mesenchymal Stem Cells / cytology; Mice; Myocardial Infarction / drug therapy; Myocardial Infarction / pathology; Myocytes, Cardiac / drug effects; Myocytes, Cardiac / pathology; Nanoparticles / chemistry; Particle Size; Surface Properties
Sources: Web Of Science, ORCID
Added: February 21, 2022

2021 journal article

Platelet membrane and stem cell exosome hybrids enhance cellular uptake and targeting to heart injury

NANO TODAY, 39.

By: S. Hu n, X. Wang n, Z. Li n, D. Zhu n, J. Cores n, Z. Wang n, J. Li n, X. Mei n ...

author keywords: Exosomes; Targeting; Myocardial infarction; Platelet membrane; Stem cells
Sources: Web Of Science, ORCID
Added: September 7, 2021

2020 review

Engineering better stem cell therapies for treating heart diseases

[Review of ]. ANNALS OF TRANSLATIONAL MEDICINE, 8(8).

By: J. Li*, S. Hu* & K. Cheng*

author keywords: Stem cell therapy; ischemic heart diseases; bioengineering strategies; clinical translation
Sources: Web Of Science, ORCID
Added: May 26, 2020