Joshua Luke Schipper

Works (5)

Updated: April 11th, 2023 10:13
Download BibTeX Download Plain Text View JSON

2016 journal article

Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 113(41), E6080–E6088.

By: J. Maciag, S. Mackenzie, M. Tucker n, J. Schipper, P. Swartz & A. Clark

author keywords: allostery; conformational selection; saturation mutagenesis; protein solvation; protein structure
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Lengthening the Intersubunit Linker of Procaspase 3 Leads to Constitutive Activation

BIOCHEMISTRY, 52(36), 6219–6231.

By: S. MacKenzie, J. Schipper, E. England, M. Thomas, K. Blackburn, P. Swartz, A. Clark

Source: Web Of Science
Added: August 6, 2018

2012 journal article

Allosteric modulation of caspase 3 through mutagenesis

BIOSCIENCE REPORTS, 32(4), 401–411.

By: J. Walters, J. Schipper, P. Swartz, C. Mattos & A. Clark

author keywords: allosteric site; apoptosis; caspase; inhibition; protein ensemble
Source: Web Of Science
Added: August 6, 2018

2011 journal article

A bifunctional allosteric site in the dimer interface of procaspase-3

BIOPHYSICAL CHEMISTRY, 159(1), 100–109.

By: J. Schipper, S. MacKenzie, A. Sharma & A. Clark

author keywords: Caspase; Apoptosis; Allosteric activator; Drug design; Cancer therapy
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2010 review

The potential for caspases in drug discovery

[Review of ]. Current Opinion in Drug Discovery & Development, 13(5), 568–576.

By: S. MacKenzie, J. Schipper & A. Clark

Source: NC State University Libraries
Added: August 6, 2018