Works (1)

Updated: July 5th, 2023 15:41

2014 journal article

Genetically Encoded Optochemical Probes for Simultaneous Fluorescence Reporting and Light Activation of Protein Function with Two-Photon Excitation

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 136(44), 15551–15558.

By: J. Luo n, R. Uprety n, Y. Naro*, C. Chou n, D. Nguyen*, J. Chin*, A. Deiters*

MeSH headings : Chromatography, Liquid; Fluorescence; HEK293 Cells; Humans; Methanosarcina barkeri / chemistry; Molecular Probes; Photons; Proteins / chemistry; Proteins / physiology; Tandem Mass Spectrometry
TL;DR: The small size of coumarin, the site-specific incorporation, the application as both a light-activated caging group and as a fluorescent probe, and the broad range of excitation wavelengths are advantageous over other genetically encoded photocontrol systems and provide a precise and multifunctional tool for cellular biology. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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