@article{majikes_nash_labean_2017, title={Search for effective chemical quenching to arrest molecular assembly and directly monitor DNA nanostructure formation}, volume={9}, ISSN={["2040-3372"]}, DOI={10.1039/c6nr08433h}, abstractNote={Structural DNA nanotechnology has demonstrated both versatility and potential as a molecular manufacturing tool; the formation and processing of DNA nanostructures has therefore been subject to much interest. Characterization of the formation process itself is vital to understanding the role of design in production yield. We present our search for a robust new technique, chemical quenching, to arrest molecular folding in DNA systems for subsequent characterization. Toward this end we will introduce two miniM13 origami designs based on a 2.4 kb scaffold, each with diametrically opposed scaffold routing strategies (maximized scaffold crossovers versus maximized staple crossovers) to examine the relevance of design in the folding process. By chemically rendering single strand DNA inert and unable to hybridize, we probe the folding pathway of several scaffolded DNA origami structures.}, number={4}, journal={NANOSCALE}, author={Majikes, J. M. and Nash, J. A. and LaBean, T. H.}, year={2017}, month={Jan}, pages={1637–1644} } @article{majikes_ferraz_labean_2017, title={pH-Driven Actuation of DNA Origami via Parallel I-Motif Sequences in Solution and on Surfaces}, volume={28}, ISSN={["1043-1802"]}, DOI={10.1021/acs.bioconjchem.7b00288}, abstractNote={As bottom up DNA nanofabrication creates increasingly complex and dynamic mechanisms, the implementation of actuators within the DNA nanotechnology toolkit has grown increasingly important. One such actuator, the I-motif, is fairly simple in that it consists solely of standard DNA sequences and does not require any modification chemistry or special purification beyond that typical for DNA oligomer synthesis. This study presents a new implementation of parallel I-motif actuators, emphasizing their future potential as drivers of complex internal motion between substructures. Here we characterize internal motion between DNA origami substructures via AFM and image analysis. Such parallel I-motif design and quantification of actuation provide a useful step toward more complex and effective molecular machines.}, number={7}, journal={BIOCONJUGATE CHEMISTRY}, author={Majikes, Jacob M. and Ferraz, Lucas C. C. and LaBean, Thomas H.}, year={2017}, month={Jul}, pages={1821–1825} } @article{majikes_nash_labean_2016, title={Competitive annealing of multiple DNA origami: formation of chimeric origami}, volume={18}, ISSN={["1367-2630"]}, DOI={10.1088/1367-2630/18/11/115001}, abstractNote={Scaffolded DNA origami are a robust tool for building discrete nanoscale objects at high yield. This strategy ensures, in the design process, that the desired nanostructure is the minimum free energy state for the designed set of DNA sequences. Despite aiming for the minimum free energy structure, the folding process which leads to that conformation is difficult to characterize, although it has been the subject of much research. In order to shed light on the molecular folding pathways, this study intentionally frustrates the folding process of these systems by simultaneously annealing the staple pools for multiple target or parent origami structures, forcing competition. A surprising result of these competitive, simultaneous anneals is the formation of chimeric DNA origami which inherit structural regions from both parent origami. By comparing the regions inherited from the parent origami, relative stability of substructures were compared. This allowed examination of the folding process with typical characterization techniques and materials. Anneal curves were then used as a means to rapidly generate a phase diagram of anticipated behavior as a function of staple excess and parent staple ratio. This initial study shows that competitive anneals provide an exciting way to create diverse new nanostructures and may be used to examine the relative stability of various structural motifs.}, journal={NEW JOURNAL OF PHYSICS}, author={Majikes, Jacob M. and Nash, Jessica A. and LaBean, Thomas H.}, year={2016}, month={Nov} } @article{brown_majikes_martinez_giron_fennell_samano_labean_2015, title={An easy-to-prepare mini-scaffold for DNA origami}, volume={7}, ISSN={["2040-3372"]}, DOI={10.1039/c5nr04921k}, abstractNote={The DNA origami strategy for assembling designed supramolecular complexes requires ssDNA as a scaffold strand. A system is described that was designed approximately one third the length of the M13 bacteriophage genome for ease of ssDNA production. Folding of the 2404-base ssDNA scaffold into a variety of origami shapes with high assembly yields is demonstrated.}, number={40}, journal={NANOSCALE}, author={Brown, S. and Majikes, J. and Martinez, A. and Giron, T. M. and Fennell, H. and Samano, E. C. and LaBean, T. H.}, year={2015}, pages={16621–16624} } @article{campos_zhang_majikes_ferraz_labean_dong_ferapontova_2015, title={Electronically addressable nanomechanical switching of i-motif DNA origami assembled on basal plane HOPG}, volume={51}, DOI={10.1039/c5cc04678e}, abstractNote={Here, a pH-induced nanomechanical switching of i-motif structures incorporated into DNA origami bound onto cysteamine-modified basal plane HOPG was electronically addressed, demonstrating for the first time the electrochemical read-out of the nanomechanics of DNA origami. This paves the way for construction of electrode-integrated bioelectronic nanodevices exploiting DNA origami patterns on conductive supports.}, number={74}, journal={Chemical Communications}, author={Campos, R. and Zhang, S. and Majikes, J. M. and Ferraz, L. C. C. and LaBean, T. H. and Dong, M. D. and Ferapontova, E. E.}, year={2015}, pages={14111–14114} } @article{vasanthan_white_gyanwali_shin_majikes_pasquinelli_tonelli_2011, title={Unexpected Results from the Comparison of Solid-State Conformations and C-13 NMR Spectra of Poly (trimethylene terephthalate) and Its Model Compounds}, volume={44}, ISSN={["0024-9297"]}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-80052469025&partnerID=MN8TOARS}, DOI={10.1021/ma201305e}, abstractNote={ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTUnexpected Results from the Comparison of Solid-State Conformations and 13C NMR Spectra of Poly (trimethylene terephthalate) and Its Model CompoundsN. Vasanthan†, J. L. White‡, G. Gyanwali‡, I. D. Shin§, J. Majikes∥, M. A. Pasquinelli∥, and A. E. Tonelli*∥View Author Information† Department of Chemistry, Long Island University, Brooklyn, New York 11201, United States‡ Department of Chemistry, Oklahoma State University, Stillwater, Oklahoma 74078, United States§ College of Pharmacy & Health Sciences, Campbell University, Buies Creek, North Carolina 27506, United States∥ Fiber & Polymer Science, North Carolina State University, Campus Box 8301, Raleigh, North Carolina 27695-8301, United StatesE-mail: [email protected]Cite this: Macromolecules 2011, 44, 17, 7050–7055Publication Date (Web):August 17, 2011Publication History Received9 June 2011Revised1 August 2011Published online17 August 2011Published inissue 13 September 2011https://doi.org/10.1021/ma201305eCopyright © 2011 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views343Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (2 MB) Get e-AlertsSUBJECTS:Carbene compounds,Carbonyls,Conformation,Phenyls,Resonance structures Get e-Alerts}, number={17}, journal={MACROMOLECULES}, publisher={American Chemical Society}, author={Vasanthan, N. and White, J. L. and Gyanwali, G. and Shin, I. D. and Majikes, J. and Pasquinelli, M. A. and Tonelli, A. E.}, year={2011}, month={Sep}, pages={7050–7055} } @article{aberg_ozcam_majikes_seyam_spontak_2008, title={Extended chemical crosslinking of a thermoplastic polyimide: Macroscopic and microscopic property development}, volume={29}, ISSN={["1022-1336"]}, DOI={10.1002/marc.200800230}, abstractNote={Polyimides are well established as gas separation membranes due to their intrinsically low free volume and correspondingly high H 2 selectivity relative to other gases such as CO 2 . Prior studies have established that H 2 /CO 2 selectivity can be improved by crosslinking polyimides with diamines differing in spacer length. In this work, we follow the evolution of macroscopic and microscopic properties of a commercial polyimide over long crosslinking times (t x ) with 1,3-diaminopropane. According to spectroscopic analysis, the crosslinking reaction saturates after ≈24 h, whereas tensile, nanoindentation and stress relaxation tests reveal that the material stiffens, and possesses a long relaxation time that increases with increasing t x . Although differential scanning calorimetry shows that the glass transition temperature decreases systematically with increasing t x , permeation studies indicate that the permeabilities of H 2 and CO 2 decrease, while the H 2 /CO 2 selectivity increases markedly, with increasing t x . At long t x , the polyimide becomes impermeable to CO 2 , suggesting that it could be used as a barrier material.}, number={17}, journal={MACROMOLECULAR RAPID COMMUNICATIONS}, author={Aberg, Christopher M. and Ozcam, Ali E. and Majikes, Jacob M. and Seyam, Mohamed A. and Spontak, Richard J.}, year={2008}, month={Sep}, pages={1461–1466} }