Works (3)
Updated: July 5th, 2023 15:46
2017 journal article
N-Gemini peptides: cytosolic protease resistance via N-terminal dimerization of unstructured peptides
CHEMICAL COMMUNICATIONS, 54(2), 204–207.
MeSH headings : Cell Line; Cytosol / enzymology; Dimerization; HeLa Cells; Humans; Molecular Structure; Peptide Hydrolases / metabolism; Peptides / chemical synthesis; Peptides / chemistry; Peptides / pharmacology; Protease Inhibitors / chemistry; Protease Inhibitors / pharmacology
TL;DR:
A synthetically simple strategy for increasing the lifetime of unstructured peptides in cytosolic environment via dimerization at the N-terminus to block threading into the catalytic cleft of cytosolics proteases is described.
(via Semantic Scholar)
open access via doi.org (publisher)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Laser-based directed release of array elements for efficient collection into targeted microwells
ANALYST, 138(3), 831–838.
MeSH headings : Cell Line, Tumor; Cell Separation; Cell Survival; Dimethylpolysiloxanes / chemistry; Green Fluorescent Proteins / genetics; Green Fluorescent Proteins / metabolism; HeLa Cells; Humans; Lasers; Tissue Array Analysis; Transfection
TL;DR:
An array of microfabricated, releasable, transparent micron-scale pedestals termed pallets and an array of microwells in poly(dimethylsiloxane) (PDMS) were mated to enable selective release and retrieval of individual cells.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Microfluidic Cytometer for the Characterization of Cell Lysis
ANALYTICAL CHEMISTRY, 84(5), 2195–2201.
MeSH headings : Diffusion; Erythrocytes / cytology; Hemolysis; Humans; Kinetics; Microfluidic Analytical Techniques / instrumentation; Microfluidic Analytical Techniques / methods; Quaternary Ammonium Compounds / chemistry
TL;DR:
A microfluidic cytometer was fabricated and achieved complete erythrocyte lysis of a blood sample in 0.7 s under optimum conditions, and a maximum lysis reaction rate of 1.55 s(-1) was extrapolated from the data.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
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