Jenna Schirmer

Works (5)

Updated: April 5th, 2024 08:26

2019 journal article

Oral reserpine administration in horses results in low plasma concentrations that alter platelet biology


By: J. Gilbertie n, J. Davis*, G. Davidson n, A. McDonald n, J. Schirmer n & L. Schnabel n

author keywords: horse; reserpine; pharmacokinetics; tranquilisation; platelets; hypercoagulability
MeSH headings : Administration, Oral; Adrenergic Uptake Inhibitors / administration & dosage; Adrenergic Uptake Inhibitors / blood; Adrenergic Uptake Inhibitors / pharmacokinetics; Adrenergic Uptake Inhibitors / pharmacology; Animals; Area Under Curve; Blood Platelets / drug effects; Female; Half-Life; Horses / blood; Male; Reserpine / administration & dosage; Reserpine / blood; Reserpine / pharmacokinetics; Reserpine / pharmacology
Source: Web Of Science
Added: July 22, 2019

2018 journal article

Pharmacokinetics and ex vivo anti‐inflammatory effects of oral misoprostol in horses

Equine Veterinary Journal, 51(3), 415–421.

By: E. Martin n, J. Schirmer n, S. Jones n & J. Davis*

author keywords: horse; leucocyte; E prostanoid receptor agonist; pharmacokinetics; inflammation; tumour necrosis factor-
MeSH headings : Abortifacient Agents, Nonsteroidal / administration & dosage; Abortifacient Agents, Nonsteroidal / pharmacokinetics; Administration, Oral; Animals; Area Under Curve; Cells, Cultured; Horse Diseases / drug therapy; Horse Diseases / metabolism; Horses / blood; Horses / metabolism; Inflammation / drug therapy; Inflammation / metabolism; Inflammation / veterinary; Leukocytes / drug effects; Leukocytes / metabolism; Misoprostol / administration & dosage; Misoprostol / pharmacokinetics
Sources: Web Of Science, ORCID, Crossref
Added: May 6, 2019

2018 journal article

Pharmacokinetics, pharmacodynamics and clinical use of trazodone and its active metabolite m-chlorophenylpiperazine in the horse


By: J. Davis*, J. Schirmer n & E. Medlin n

author keywords: adverse drug reaction; equine; sedative; serotonin antagonist and reuptake inhibitor
MeSH headings : Administration, Oral; Animals; Anti-Anxiety Agents / administration & dosage; Anti-Anxiety Agents / pharmacokinetics; Anti-Anxiety Agents / pharmacology; Area Under Curve; Cross-Over Studies; Dose-Response Relationship, Drug; Half-Life; Horses / blood; Male; Piperazines / administration & dosage; Piperazines / pharmacokinetics; Piperazines / pharmacology; Serotonin Receptor Agonists / administration & dosage; Serotonin Receptor Agonists / pharmacokinetics; Serotonin Receptor Agonists / pharmacology; Trazodone / administration & dosage; Trazodone / pharmacokinetics; Trazodone / pharmacology
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Effects of quinapril on angiotensin converting enzyme and plasma renin activity as well as pharmacokinetic parameters of quinapril and its active metabolite, quinaprilat, after intravenous and oral administration to mature horses


By: J. Davis n, K. Kruger n, D. LaFevers n, B. Barlow n, J. Schirmer n & B. Breuhaus n

author keywords: horse; angiotensin converting enzyme; renin; mitral insufficiency
MeSH headings : Administration, Intravenous; Administration, Oral; Angiotensin-Converting Enzyme Inhibitors / blood; Angiotensin-Converting Enzyme Inhibitors / metabolism; Angiotensin-Converting Enzyme Inhibitors / pharmacokinetics; Angiotensin-Converting Enzyme Inhibitors / pharmacology; Animals; Area Under Curve; Gene Expression Regulation, Enzymologic; Half-Life; Horses / blood; Horses / metabolism; Peptidyl-Dipeptidase A / blood; Peptidyl-Dipeptidase A / genetics; Peptidyl-Dipeptidase A / metabolism; Quinapril; Renin / blood; Tetrahydroisoquinolines / blood; Tetrahydroisoquinolines / metabolism; Tetrahydroisoquinolines / pharmacokinetics; Tetrahydroisoquinolines / pharmacology
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Pharmacokinetics and pharmacodynamics of three formulations of firocoxib in healthy horses

Journal of Veterinary Pharmacology and Therapeutics, 38(3), 249–256.

By: B. Holland n, C. Fogle n, A. Blikslager n, A. Curling n, B. Barlow n, J. Schirmer n, J. Davis n

Contributors: B. Holland n, C. Fogle n, A. Blikslager n, A. Curling n, B. Barlow n, J. Schirmer n, J. Davis n

MeSH headings : 4-Butyrolactone / administration & dosage; 4-Butyrolactone / analogs & derivatives; 4-Butyrolactone / blood; 4-Butyrolactone / pharmacokinetics; 4-Butyrolactone / pharmacology; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal / administration & dosage; Anti-Inflammatory Agents, Non-Steroidal / blood; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Anti-Inflammatory Agents, Non-Steroidal / pharmacology; Cross-Over Studies; Dinoprostone / blood; Horses / metabolism; Injections, Intravenous / veterinary; Ointments; Sulfones / administration & dosage; Sulfones / blood; Sulfones / pharmacokinetics; Sulfones / pharmacology; Tablets; Thromboxane B2 / blood
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

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