A comparison of DMET Plus microarray and genome-wide technologies by assessing population substructure
Jackson, J. N., Long, K. M., He, Y., Motsinger-Reif, A. A., McLeod, H. L., & Jack, J. (2016, January 5). Pharmacogenetics and Genomics.
author keywords: admixture; Affymetrix; cryptic relatedness; DMET Plus; inbreeding coefficients; metabolism; pharmacogenomics; population stratification; principal component analysis; transporters
topics (OpenAlex): Genetic Associations and Epidemiology; Gene expression and cancer classification; Genomic variations and chromosomal abnormalities
TL;DR:
The DMET Plus pharmacogenomics genotyping chip is effective in quantifying population substructure across the three continental populations and inferring the presence of an admixed population.
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