Works (709)

Updated: February 10th, 2025 14:29

2025 journal article

Single-cell transcriptomics predict novel potential regulators of acute epithelial restitution in the ischemia-injured intestine

American Journal of Physiology-Gastrointestinal and Liver Physiology.

By: E. Rose n, J. Simon*, I. Gomez-Martinez*, S. Magness*, J. Odle n, A. Blikslager n, A. Ziegler n

Source: ORCID
Added: January 24, 2025

2024 journal article

Dietary Zn proteinate with moderate chelation strength alleviates heat stress-induced intestinal barrier function damage by promoting expression of tight junction proteins via the A20/NF-κB p65/MMP-2 pathway in the jejunum of broilers

JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY, 15(1).

By: Y. Hu*, W. Zhang*, K. Yang*, . Lin n, H. Liu n, J. Odle n, M. See n, X. Cui* ...

author keywords: A20/NF-kappa B p65/MMP-2 pathway; Broiler; Heat stress; Intestinal barrier function; Tight junction proteins; Zn
Sources: Web Of Science, NC State University Libraries
Added: September 9, 2024

2024 journal article

Effects of maternal feeding of clofibrate on hepatic fatty acid metabolism in suckling piglet

JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY, 15(1).

By: J. Zhao n, B. Pike n, F. Wang n, L. Yang n, P. Meisner n, Y. Huang n, J. Odle n, . Lin n

author keywords: Clofibrate; Hepatic fatty acid oxidation and metabolism; Newborn pigs; Postnatal age, PPAR alpha
Sources: Web Of Science, NC State University Libraries
Added: December 16, 2024

2024 journal article

Prebiotic galactooligosaccharide improves piglet growth performance and intestinal health associated with alterations of the hindgut microbiota during the peri-weaning period

JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY, 15(1).

By: T. Boston n, F. Wang n, . Lin n, S. Kim n, V. Fellner n, M. Scott, A. Ziegler n, L. Van Landeghem n, A. Blikslager n, J. Odle n

author keywords: Galactooligosaccharide; Gut microbiome; Intestinal villi; Prebiotics; Weaning
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 15, 2024

2024 journal article

Protocol Protocol to culture enteric glial cells from the submucosal and myenteric plexi of neonatal and juvenile pig colons

STAR PROTOCOLS, 5(2).

Sources: Web Of Science, NC State University Libraries
Added: June 24, 2024

2024 article

The Carnitine

Lin, Xi, Adams, S. H., Vockley, J., & Odle, J. (2024, December). ADVANCES IN NUTRITION, Vol. 15.

By: . Lin n, S. Adams*, J. Vockley* & J. Odle n

Sources: ORCID, Web Of Science, NC State University Libraries
Added: November 5, 2024

2024 journal article

Zinc alleviates thermal stress-induced damage to the integrity and barrier function of cultured chicken embryonic primary jejunal epithelial cells via the MAPK and PI3K/AKT/mTOR signaling pathways

Poultry Science.

By: L. Huang*, C. Cao*, X. Lin*, L. Lu*, H. Liu n, J. Odle n, M. See n, L. Zhang* ...

Source: ORCID
Added: April 15, 2024

2023 journal article

Dietary Prebiotic Oligosaccharides and Arachidonate Alter the Fecal Microbiota and Mucosal Lipid Composition of Suckling Pigs

JOURNAL OF NUTRITION, 153(8), 2249–2262.

By: B. Eudy n, J. Odle n, . Lin n, C. Maltecca n, K. Walter n, N. McNulty*, V. Fellner n, S. Jacobi*

author keywords: microbiota; ARA; prebiotics; oligosaccharides; infant formula
TL;DR: Although dietary ARA did not alter the microbiota, prebiotic supplementation during the first 22 days of life increased the ARA content of the colonic mucosa, which may support intestinal development and epithelial repair. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: September 11, 2023

2023 article

Effects of Prebiotic Galactooligosaccharide (GOS) on Hindgut Microbial Composition of Pigs During the Peri-Weaning Period

Boston, T. E., Wang, F., Xi, L., Kim, S. W., Fellner, V., Scott, M. F., … Odle, J. (2023, November 6). JOURNAL OF ANIMAL SCIENCE, Vol. 101, pp. 187–188.

By: T. Boston n, F. Wang n, L. Xi n, S. Kim n, V. Fellner n, M. Scott, A. Ziegler n, L. Van Landeghem n, A. Blikslager n, J. Odle n

author keywords: microbiome; prebiotics; weaning
Sources: Web Of Science, NC State University Libraries
Added: December 18, 2023

2023 article

Effects of Prebiotic Galactooligosaccharide (Gos) on Piglet Growth and Jejunal Morphology During the Peri-Weaning Period

Boston, T. E., Wang, F., Xi, L., Kim, S. W., Fellner, V., Scott, M. F., … Odle, J. (2023, October 28). JOURNAL OF ANIMAL SCIENCE, Vol. 101, pp. 276–277.

By: T. Boston n, F. Wang n, L. Xi n, S. Kim n, V. Fellner n, M. Scott, A. Ziegler n, L. Van Landeghem n, A. Blikslager n, J. Odle n

author keywords: intestinal villi; galactooligosaccharides; prebiotics; weaning
Sources: Web Of Science, NC State University Libraries
Added: December 18, 2023

2023 journal article

Enteric glial cell network function is required for epithelial barrier restitution following intestinal ischemic injury in the early postnatal period

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 326(3), G228–G246.

By: A. Ziegler n, M. Caldwell n, S. Craig, E. Hellstrom n, A. Sheridan n, M. Touvron n, T. Pridgen n, S. Magness* ...

author keywords: enteric glia; epithelial restitution; intestinal barrier; intestinal ischemia; restitution
TL;DR: A neonatal phenotype characterized by a complete lack of coordinated reparative signaling in the mucosal microenvironment is confirmed and important evidence is reported that the subepithelial EGC network changes significantly over the early postnatal period and that proximity of a specific functional population of EGC to wounded intestinal epithelium contributes to intestinal barrier restitution following ischemic injury. (via Semantic Scholar)
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3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 12, 2024

2023 article

Exploring the Prebiotic Activities of Proanthocyanidins on a Platform Using the Three-Dimensionally (3D)-Cultured Organoids

Xi, L., Wang, F., Cagle, D., Zhu, Y., Odle, J., & Xie, D. (2023, November 6). JOURNAL OF ANIMAL SCIENCE, Vol. 101, pp. 355–356.

By: L. Xi n, F. Wang n, D. Cagle n, Y. Zhu n, J. Odle n & D. Xie n

author keywords: antibiotics; Interleukins; organoids
TL;DR: It is concluded that epigallocatechin gallate is a potential PA monomer with all prebiotic characteristics and its applicable values in feedstuff and food supply should be studied in vivo studies in domestic (food) animals with and without antigen challenges. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: December 11, 2023

2023 journal article

Intestinal Carnitine Status and Fatty Acid Oxidation in Response to Clofibrate and Medium-Chain Triglyceride Supplementation in Newborn Pigs

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24(7).

By: B. Pike n, J. Zhao n, J. Hicks n, F. Wang n, R. Hagen n, H. Liu n, J. Odle n, . Lin n

author keywords: carnitine; fatty acid oxidation; intestine; medium-chain fatty acid; newborn pigs
MeSH headings : Animals; Swine; Clofibrate / pharmacology; Animals, Newborn; Carnitine / pharmacology; Carnitine / metabolism; Liver / metabolism; Palmitic Acid / pharmacology; Triglycerides / metabolism; Intestines; Dietary Supplements; Fatty Acids / metabolism; Oxidation-Reduction
TL;DR: It is suggested that dietary clofibrate improved carnitine status and increased fatty acid oxidation in neonates, and Propionyl-CoA, generated from TC5 and TMPA, could stimulate the increased fatty acids oxidation rate induced by cl ofibrate as anaplerotic carbon sources. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: March 25, 2023

2023 journal article

MicroRNA and mRNA sequencing analyses reveal key hepatic metabolic and signaling pathways responsive to maternal undernutrition in full-term fetal pigs

JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 116.

By: F. Wang n, C. Man n, X. Wang n, J. Odle n, C. Maltecca n & . Lin n

author keywords: Maternal undernutrition; RNA sequencing; mRNA-miRNA correlation analysis; Ingenuity Pathways Analysis (IPA); Oxidative phosphorylation
MeSH headings : Pregnancy; Female; Animals; Swine; RNA, Messenger / metabolism; Fetus / metabolism; Liver / metabolism; Signal Transduction; Malnutrition / metabolism
TL;DR: The correlation analyses showed that metabolic and signaling pathways such as oxidative phosphorylation, death receptor signaling, neuroinflammation signaling pathway, and estrogen receptor signaling pathways were significantly modified, and the gene modifications in these pathways were associated with the miRNA changes induced by the maternal undernutrition. (via Semantic Scholar)
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5. Gender Equality (Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: March 4, 2023

2022 journal article

Effects of medium chain triglycerides on hepatic fatty acid oxidation in clofibrate-fed newborn piglets

ANIMAL NUTRITION, 12, 334–344.

By: J. Zhao n, B. Pike n, J. Huang n, Z. Feng n, J. Odle n & . Lin n

author keywords: PPAR a; Clofibrate; Newborn piglets; Medium chain triglyceride (MCT); Hepatic fatty acid oxidation
TL;DR: It is suggested that dietary supplementation of anaplerotic and ketogenic FA could impact FA oxidation and modify the metabolism of acetyl-CoA via alteration of TCA cycle activity, but the modification has no significant impact on the hepatic FA oxidative capacity induced by PPARα. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: February 20, 2023

2022 article

Enteric Glial Cell Network Function is Required for Epithelial Barrier Restitution following Intestinal Ischemic Injury in the Early Postnatal Period

Ziegler, A. L., Erwin, S., Caldwell, M. L., Touvron, M. S., Pridgen, T. A., Magness, S. T., … Blikslager, A. T. (2022, November 4).

TL;DR: It is suggested that targeting the enteric glial network could lead to novel interventions to improve recovery from intestinal injury in neonatal patients and demonstrate that EGC function in close proximity to wounded intestinal epithelium is critical to intestinal barrier restitution following ischemic injury. (via Semantic Scholar)
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3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: November 5, 2022

2022 journal article

Gruel Creep Feeding Accelerates Growth and Alters Intestinal Health of Young Pigs

ANIMALS, 12(18).

By: T. Boston n, F. Wang n, . Lin n, S. Leonard n, S. Kim n, D. McKilligan, V. Fellner n, J. Odle n

Contributors: T. Boston n, F. Wang n, . Lin n, S. Leonard n, S. Kim n, D. McKilligan, V. Fellner n, J. Odle n

author keywords: creep feeding; intestinal health; piglet growth; weaning
Sources: ORCID, Web Of Science, NC State University Libraries
Added: September 15, 2022

2022 journal article

Immunologic and pathologic characterization of a novel swine biomedical research model for eosinophilic esophagitis

FRONTIERS IN ALLERGY, 3.

By: L. Cortes n, D. Brodsky n, C. Chen, T. Pridgen n, J. Odle n, D. Snider n, G. Cruse n, A. Putikova* ...

author keywords: pig; food allergy; animal model; immunology; gastrointestinal; eosinophilic esophagitis
TL;DR: Swine is established as a relevant large animal model for translational biomedical research in EoE with the potential to facilitate development of therapeutics and it is demonstrated that the sensitization and oral challenge protocol not only induces the underlying immune markers but also the micro- and macro-pathological hallmarks of human EiE. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: September 25, 2023

2022 journal article

The health benefits of selenium in food animals: a review

Journal of Animal Science and Biotechnology, 13(1), 58.

By: B. Pecoraro n, D. Leal n, A. Frias-De-Diego n, M. Browning n, J. Odle n & E. Crisci n

author keywords: Antimicrobial; Antioxidant; Food animals; Immunomodulation; Pig; Selenium
TL;DR: The review demonstrates the gaps in knowledge pertaining to the use of selenium as an antiviral, underscoring the need for further in vivo and in vitro studies, particularly in pigs. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: May 13, 2022

2021 journal article

A guide for authors and readers of the American Society for Nutrition Journals on the proper use of P values and strategies that promote transparency and improve research reproducibility

The American Journal of Clinical Nutrition, 114(4), 1280–1285.

By: J. Sorkin*, M. Manary*, P. Smeets*, A. MacFarlane*, A. Astrup*, R. Prigeon*, B. Hogans, J. Odle n ...

author keywords: transparency; reproducibility; reliability; P value; strategies
MeSH headings : Disclosure; Editorial Policies; Humans; Nutritional Sciences; Periodicals as Topic; Publishing / standards; Reproducibility of Results; Research Design / statistics & numerical data; United States
TL;DR: How P values can be used in a manner that is consistent with the scientific method and to increase transparency and reproducibility in the conduct and analysis of nutrition research is discussed. (via Semantic Scholar)
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Sources: ORCID, Web Of Science, NC State University Libraries, Crossref
Added: July 14, 2021

2021 personal communication

ASN guidelines on P values Reply

Sorkin, J. D., Manary, M., Smeets, P. A. M., MacFarlane, A. J., Astrup, A., Prigeon, R. L., … Tobias, D. K. (2022, February 9).

By: J. Sorkin*, M. Manary*, P. Smeets*, A. MacFarlane*, A. Astrup*, R. Prigeon*, B. Hogans, J. Odle n ...

TL;DR: It is argued that statistically significant results should be interpreted taking the prior expectation and plausibility of the null hypothesis into account, and CIs should generally not be reported as (non)significant, and they should not be used unless there are good reasons for doing so. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 10, 2022

2021 speech

Annual review and Evaluation of Current Developments in Nutrition

Odle, J. (2021, May). Editor-in-Chief Report presented at the American Society of Nutrition.

By: J. Odle

Event: American Society of Nutrition on May 18, 2021

Source: NC State University Libraries
Added: February 26, 2022

2021 conference paper

Dietary Oligosaccharides Differentially Modulate Microbiome, Enteric Glia, and Epithelial Barrier Function in the Early Postnatal Period

Ziegler, A., Deck, C., Caldwell, M., Pridgen, T., Rose, E., Sheridan, A., … Blikslager, A. (2021, August 3). Presented at the Gastrointestinal Tract XIX Conference: Making and Breaking a Gut (FASEB Science Research Conference), (Virtual).

By: A. Ziegler, C. Deck, M. Caldwell, T. Pridgen, E. Rose, A. Sheridan, S. Erwin, B. Wieland ...

Event: Gastrointestinal Tract XIX Conference: Making and Breaking a Gut (FASEB Science Research Conference) at (Virtual) on August 3, 2021

Source: NC State University Libraries
Added: February 26, 2022

2021 conference paper

Domestic pigs represent a novel translational animal model for eosinophilic esophagitis

Brodsky, D., Cortes, L. M., Pridgen, T., Schaaf, C., McKinney, C., Hazzard, A., … Kaeser, T. (2021, August 30). Presented at the European Veterinary Immunology Workshop, (Virtual).

By: D. Brodsky, L. Cortes, T. Pridgen, C. Schaaf, C. McKinney, A. Hazzard, J. Odle, A. Blikslager ...

Event: European Veterinary Immunology Workshop at (Virtual) on August 30, 2021

Source: NC State University Libraries
Added: February 26, 2022

2021 journal article

Gut microbiome contributions to altered metabolism in a pig model of undernutrition

Proceedings of the National Academy of Sciences, 118(21), e2024446118.

author keywords: gut microbiome; malnutrition; carbohydrate-active enzymes; metabolic regulation; feature selection/information theory
MeSH headings : Algorithms; Animals; Body Weight; Butyrates / metabolism; Diet / methods; Diet Therapy / methods; Disease Models, Animal; Feces / microbiology; Gastrointestinal Microbiome / physiology; Germ-Free Life; Lipid Metabolism / physiology; Liver / metabolism; Male; Malnutrition / metabolism; Malnutrition / physiopathology; Mice; Mice, Inbred C57BL; Phosphoric Monoester Hydrolases / metabolism; Starch / metabolism; Sucrose / metabolism; Swine; Taurocholic Acid / metabolism; alpha-Glucosidases / metabolism
TL;DR: Using an intergenerational pig model of diet restriction (DR) that reduces weight gain, a feature-selection algorithm is developed to identify representative characteristics distinguishing DR fecal microbiomes from those of full-fed (FF) pigs as both groups consumed a common sequence of diets during their growth cycle. (via Semantic Scholar)
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2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: June 21, 2021

2021 speech

Manuscript 101: Tips for preparing your research for publication

Odle, J. (2021, November). Workshop presentation presented at the Student Interest Group of the American Society for Nutrition, (Virtual).

By: J. Odle

Event: Student Interest Group of the American Society for Nutrition at (Virtual) on November 18, 2021

Source: NC State University Libraries
Added: February 26, 2022

2021 journal article

Metabolic Regulation of Intestinal Stem Cell Homeostasis

Trends in Cell Biology, 31(5), 325–327.

By: D. Wang*, J. Odle n & Y. Liu*

MeSH headings : Animals; Cell Differentiation; Cell Proliferation; Homeostasis / physiology; Humans; Intestinal Mucosa / metabolism; Metabolic Networks and Pathways / physiology; Signal Transduction; Stem Cells / cytology; Stem Cells / metabolism
TL;DR: Recent evidences indicate that metabolic pathways sense changes in nutritional status to control stem cell fate, which may provide new clues for the prevention of intestinal diseases. (via Semantic Scholar)
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2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: May 24, 2021

2021 journal article

MicroRNA and mRNA Sequencing Analyses Reveal Key Hepatic Metabolic Pathways Responsive to Maternal Malnutrition in Full-Term Fetal Pigs

Current Developments in Nutrition, 5(Supplement_2), 829–829.

By: F. Wang n, C. Maltecca n, X. Wang n, J. Odle n & L. Xi n

TL;DR: The results provide the framework for further understanding of negative impact of maternal malnutrition on hepatic metabolic pathways via miRNA-RNA interactions in full-term fetal pigs. (via Semantic Scholar)
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2. Zero Hunger (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 9, 2022

2021 journal article

Modulation of intestinal stem cell homeostasis by nutrients: a novel therapeutic option for intestinal diseases

Nutrition Research Reviews, 6, 1–9.

By: D. Wang*, P. Li*, J. Odle n, X. Lin n, J. Zhao*, K. Xiao*, Y. Liu*

author keywords: Intestinal stem cells; Self-renewal; Differentiation; Dietary patterns; Intestinal diseases
MeSH headings : Diet, High-Fat; Homeostasis; Humans; Intestinal Diseases / therapy; Nutrients; Stem Cells / metabolism
TL;DR: The current understanding of how intestinal stem cells contribute to intestinal epithelial homeostasis and diseases is summarized and the effects of diet and nutrient-sensing pathways on intestinal stem cell self-renewal and differentiation are discussed, as well as their potential application in the prevention and treatment of intestinal diseases. (via Semantic Scholar)
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2. Zero Hunger (OpenAlex)
Sources: Crossref, NC State University Libraries, Web Of Science
Added: February 9, 2022

2021 speech

Nutritional Biochemistry of Bioactive Fatty Acids in the Neonatal Pig

Odle, J. (2021, March). Presented at the Interdepartmental Graduate Program in Nutritional Sciences, University of Wisconsin-Madison.

By: J. Odle

Event: Interdepartmental Graduate Program in Nutritional Sciences at University of Wisconsin-Madison on March 17, 2021

Source: NC State University Libraries
Added: February 26, 2022

2021 journal article

Probiotics, Prebiotics and Epithelial Tight Junctions: A Promising Approach to Modulate Intestinal Barrier Function

International Journal of Molecular Sciences, 22(13), 6729.

By: E. Rose n, J. Odle n, A. Blikslager n & A. Ziegler n

author keywords: probiotics; prebiotics; bioactive compounds; intestinal barrier function; tight junctions; toll-like receptors; intestinal microbiota
MeSH headings : Gastrointestinal Microbiome / drug effects; Gastrointestinal Microbiome / physiology; Humans; Infant; Intestinal Mucosa / cytology; Intestinal Mucosa / drug effects; Intestinal Mucosa / physiology; Prebiotics; Probiotics / pharmacology; Tight Junction Proteins / metabolism; Tight Junctions / metabolism; Toll-Like Receptors / metabolism
TL;DR: Current views on the effects of pro- and prebiotics on the intestinal epithelial barrier as well as on non-epithelial cell barrier constituents, such as the enteric glial cell network are summarized. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries, Crossref
Added: June 24, 2021

2021 conference paper

The pig -- A novel translational animal model for eosinophilic esophagitis

Brodsky, D., Cortes, L. M., Pridgen, T., Schaaf, C., McKinney, C., Hazzard, A., … Kaeser, T. (2021, December 6). Presented at the Conference of Research Workers in Animal Diseases (CRWAD), Chicago, IL.

By: D. Brodsky, L. Cortes, T. Pridgen, C. Schaaf, C. McKinney, A. Hazzard, J. Odle, A. Blikslager ...

Event: Conference of Research Workers in Animal Diseases (CRWAD) at Chicago, IL on December 6, 2021

Source: NC State University Libraries
Added: February 26, 2022

2021 speech

Understanding the peer review process

Odle, J. (2021, June). Meet the Editors session presented at the American Society of Nutrition Virtual Annual Meeting.

By: J. Odle

Event: American Society of Nutrition Virtual Annual Meeting on June 7, 2021

Source: NC State University Libraries
Added: February 26, 2022

2020 journal article

4212 An age-dependent, rescuable defect in intestinal barrier repair is associated with an immature enteric glial network in a neonatal pig model of intestinal ischemia

Journal of Clinical and Translational Science, 4(s1), 92–93.

TL;DR: Findings provide important evidence that a developing glial network may be critical to the postnatal development of intestinal barrier repair mechanisms and explore glial-epithelial interactions in vitro to further define postnatalDevelopment of barrier repair. (via Semantic Scholar)
Source: ORCID
Added: December 3, 2020

2020 article

A Glial Cell Inhibitor Blocks Epithelial Barrier Repair in a Pig Model of Intestinal Ischemia

Sheridan, A., Pridgen, T., Odle, J., Van Landeghem, L., Blikslager, A., & Ziegler, A. (2020, April). FASEB JOURNAL, Vol. 34.

By: A. Sheridan*, T. Pridgen*, J. Odle*, L. Van Landeghem*, A. Blikslager* & A. Ziegler*

TL;DR: It is hypothesized that EGC inhibition in juveniles will block epithelial barrier repair after ischemic injury mimicking the neonatal phenotype, and the development of glial‐epithelial crosstalk in barrier repair will ultimately guide novel clinical solutions to improve outcomes in neonatal patients affected by intestinal injury. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 12, 2020

2020 speech

Annual review and Evaluation of Current Developments in Nutrition

Odle, J. (2020, July). Editor-in-Chief Report presented at the American Society of Nutrition.

By: J. Odle

Event: American Society of Nutrition on July 7, 2020

Source: NC State University Libraries
Added: February 26, 2022

2020 conference paper

Dietary oligosaccharides modulate microbiome, enteric glia, and epithelial barrier function in a neonatal pig model

Proceedings of CRWAD, Conference of Research Workers in Animal Diseases. Online Dec 5-8. Abst # 431, 331.

By: A. Ziegler, T. Pridgen, E. Rose, A. Sheridan, B. Wieland, A. Hattenhauer, L. Van Landeghem, J. Odle, A. Blikslager

Event: Conference of Research Workers in Animal Diseases at (Virtual) on December 5-8, 2020

Source: NC State University Libraries
Added: February 26, 2022

2020 journal article

Effects of Dietary Anaplerotic and Ketogenic Energy Sources on Renal Fatty Acid Oxidation Induced by Clofibrate in Suckling Neonatal Pigs

International Journal of Molecular Sciences, 21(3), 726.

By: X. Lin n, B. Pike n, J. Zhao n, Y. Fan n, Y. Zhu n, Y. Zhang n, F. Wang n, J. Odle n

Contributors: X. Lin n, B. Pike n, J. Zhao n, Y. Fan n, Y. Zhu n, Y. Zhang n, F. Wang n, J. Odle n

author keywords: Renal fatty acid oxidation; anaplerotic and ketogenic energy; PPAR alpha activation
MeSH headings : Animals; Animals, Newborn; Carnitine / pharmacology; Clofibrate / pharmacology; Diet; Fatty Acids / metabolism; Ketone Bodies / metabolism; Kidney / drug effects; Kidney / metabolism; Lipid Metabolism / drug effects; Lipid Metabolism / physiology; Milk / metabolism; Oxidation-Reduction / drug effects; PPAR alpha / metabolism; Palmitic Acid / metabolism; Swine
TL;DR: Modification of anaplerosis or ketogenesis via dietary substrates had no influence on in vitro renal palmitic acid oxidation induced by PPARα activation. (via Semantic Scholar)
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7. Affordable and Clean Energy (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: February 4, 2020

2020 article

Effects of Oligosaccharide Supplementation on Intestinal Morphology and Enteric Glial Cell Marker Expression in a Neonatal Pig Model

Shapiro, L., Ziegler, A., Odle, J., Van Landeghem, L., & Blikslager, A. (2020, April). FASEB JOURNAL, Vol. 34.

By: L. Shapiro n, A. Ziegler n, J. Odle n, L. Van Landeghem n & A. Blikslager n

TL;DR: Test the effects of dietary oligosaccharides on postnatal changes in the EGC network and intestinal morphology in a neonatal pig model to find increased mucosal expression of EGC markers earlier in postnatal development in the high oligOSaccharide group, as well as histological changes consistent with enhanced rates of gut maturation in pigs fed a high oligosACcharide diet. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 12, 2020

2020 journal article

Maternal Feeding of a Synthetic PPARα Agonist Alters Renal Development of Fatty Acid Metabolism in the Neonatal Piglet

Current Developments in Nutrition, 4(Supplement_2), 702–702.

By: L. Xi n, B. Pike n, J. Zhao n & J. Odle n

TL;DR: The stimulatory effect of maternal clofibrate on renal fatty acid metabolism in offspring is associated with the postnatal age, being greater at d1 and d7 than d14 and d19, but decreased 14C-ESP measured in d7 pigs. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: December 3, 2020

2020 journal article

Maternal Supplementation of Clofibrate Stimulates Hepatic Fatty Acid Oxidation in Newborn Suckling Piglets

Current Developments in Nutrition, 4(Supplement_2), 703–703.

By: J. Zhao n, B. Pike n, J. Odle n & L. Xi n

Sources: ORCID, Crossref, NC State University Libraries
Added: December 3, 2020

2020 journal article

Ontogeny of carnitine biosynthesis in Sus scrofa domesticus, inferred from γ-butyrobetaine hydroxylase (dioxygenase) activity and substrate inhibition

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 319(1), R43–R49.

By: X. Lin n, P. Lyvers Peffer n, J. Woodworth* & J. Odle n

Contributors: X. Lin n, P. Lyvers Peffer n, J. Woodworth* & J. Odle n

author keywords: gamma-butyrobetaine hydroxylase; carnitine synthesis; development; kinetics; substrate inhibition
MeSH headings : Aging / metabolism; Animals; Animals, Newborn; Body Weight; Carnitine / biosynthesis; Enzyme Inhibitors / pharmacology; Kidney / enzymology; Kidney / growth & development; Kidney / metabolism; Kinetics; Liver / enzymology; Liver / growth & development; Liver / metabolism; Organ Size; Sus scrofa; Swine; gamma-Butyrobetaine Dioxygenase / antagonists & inhibitors; gamma-Butyrobetaine Dioxygenase / metabolism
TL;DR: Age and substrate affect γ-BBH specific activity and Km in liver and kidney and while the predominant organ for carnitine synthesis is likely the kidney at birth, the liver appears to predominate after the pig exceeds 7 day of age. (via Semantic Scholar)
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Sources: ORCID, Crossref, NC State University Libraries
Added: June 23, 2020

2020 journal article

What Constitutes a Gluconeogenic Precursor?

The Journal of Nutrition, 150(9), 2239–2241.

By: M. Tetrick* & J. Odle n

Contributors: M. Tetrick* & J. Odle n

author keywords: acetone; anaplerotic reactions; fatty acids; gluconeogenesis; gluconeogenic precursors; glyoxylate cycle; tricarboxylic acid cycle; precursor
MeSH headings : Acetyl Coenzyme A / metabolism; Carbon / metabolism; Citric Acid Cycle; Fatty Acids / metabolism; Gluconeogenesis / physiology; Glucose / biosynthesis; Glyoxylates / metabolism; Humans; Oxidation-Reduction
TL;DR: ECFAs do not meet the criteria to be recognized as a gluconeogenic precursor via the TCA cycle alone, and the net synthesis of glucose from even-chain length fatty acids in fasting placental mammals via C3 metabolism of acetone may be a competent though inefficient metabolic path. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: September 28, 2020

2020 article

iDISCO Allows Complete Visualization and Analysis of Postnatal Enteric Nervous System Development in a Comparative Pig Model

Erwin, S., Touvron, M., Odle, J., Van Landeghem, L., Blikslager, A., & Ziegler, A. (2020, April). FASEB JOURNAL, Vol. 34.

By: S. Erwin n, M. Touvron*, J. Odle n, L. Van Landeghem n, A. Blikslager n & A. Ziegler n

Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 12, 2020

2019 journal article

292 Differential gene expression analysis for piglets supplied dietary prebiotics and arachidonic acid for gastrointestinal disturbances

Journal of Animal Science, 97(Supplement_3), 122–123.

By: Y. He n, S. Jacobi*, C. Maltecca n & J. Odle n

TL;DR: DE genes identified in this study are involved in various signaling pathways with supplied prebiotics significantly changing the gene expression in pigs afflicted with colitis. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 20, 2022

2019 speech

Bioactive Nutrients Impacting GI Health of the Neonate

Odle, J. (2019, November). Presented at the Animal Health and Nutrition Intellectual Exchange Group of the NC Biotechnology Center, Research Triangle Park, NC.

By: J. Odle

Event: Animal Health and Nutrition Intellectual Exchange Group of the NC Biotechnology Center at Research Triangle Park, NC on November 4, 2019

Source: NC State University Libraries
Added: February 26, 2022

2019 journal article

Correction: Epithelial restitution defect in neonatal jejunum is rescued by juvenile mucosal homogenate in a pig model of intestinal ischemic injury and repair

PLOS ONE, 14(2), e0212962.

By: A. Ziegler, T. Pridgen, J. Mills, L. Gonzalez, L. Van Landeghem, J. Odle*, A. Blikslager

Contributors: A. Ziegler, T. Pridgen, J. Mills, L. Gonzalez, L. Van Landeghem, J. Odle*, A. Blikslager

TL;DR: This research presents a novel probabilistic approach to estimating the response of the immune system to laser-spot assisted, 3D image analysis of central nervous system injury. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: December 3, 2020

2019 journal article

Dietary arachidonate in milk replacer triggers dual benefits of PGE2 signaling in LPS-challenged piglet alveolar macrophages

Journal of Animal Science and Biotechnology, 10(1).

By: K. Walter n, X. Lin n, S. Jacobi*, T. Käser n, D. Esposito n & J. Odle n

Contributors: K. Walter n, X. Lin n, S. Jacobi*, T. Käser n, D. Esposito n & J. Odle n

author keywords: Arachidonic acid; Cyclooxygenase; Eicosanoid; Eicosapentaenoic acid; Inflammation; Lipid mediator class switch; LPS; Lipoxin; Porcine alveolar macrophage
TL;DR: It is inferred that enriching diets with arachidonic acid may be an effective means to enhance a stronger innate immunologic response to respiratory challenges in neonatal pigs, but further work is needed to examine long-term safety, clinical efficacy and economic viability. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: April 20, 2020

2019 conference paper

Dietary variables impacting the development of the fecal microbiome of piglets fed milk formula

Presented at the Duke Microbiome Center. Symposium on Food Systems, Nutrition and the Microbiome.

By: S. Jacobi, X. Lin, C. Maltecca, K. Walter, A. Smith, V. Fellner, J. Odle

Event: Duke Microbiome Center. Symposium on Food Systems, Nutrition and the Microbiome on November 12, 2019

Source: NC State University Libraries
Added: February 26, 2022

2019 journal article

EPA and DHA Inhibit Myogenesis and Downregulate the Expression of Muscle-related Genes in C2C12 Myoblasts

Genes, 10(1), 64.

author keywords: C2C12; proliferation; differentiation; EPA; DHA
MeSH headings : Animals; Cell Differentiation; Cell Line; Docosahexaenoic Acids / pharmacology; Down-Regulation; Eicosapentaenoic Acid / pharmacology; Insulin-Like Growth Factor II / genetics; Insulin-Like Growth Factor II / metabolism; MAP Kinase Signaling System; Mice; Muscle Development; Myoblasts / cytology; Myoblasts / drug effects; Myoblasts / metabolism; Myoglobin / genetics; Myoglobin / metabolism; Myosin Heavy Chains / genetics; Myosin Heavy Chains / metabolism; Myosin Light Chains / genetics; Myosin Light Chains / metabolism; Troponin / genetics; Troponin / metabolism
TL;DR: It is suggested that EPA and DHA exerted an inhibitory effect on myoblast proliferation and differentiation and downregulated muscle-related genes expression. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: March 18, 2019

2019 journal article

EPA and DHA attenuate deoxynivalenol‐induced intestinal porcine epithelial cell injury and protect barrier function integrity by inhibiting necroptosis signaling pathway

The FASEB Journal, 34(2), 2483–2496.

author keywords: barrier function; cell injury; deoxynivalenol; necroptosis signaling pathway; n-3 PUFA
MeSH headings : Animals; Docosahexaenoic Acids / pharmacology; Eicosapentaenoic Acid / pharmacology; Epithelial Cells / metabolism; Epithelial Cells / pathology; Intestinal Mucosa / injuries; Intestinal Mucosa / metabolism; Intestinal Mucosa / pathology; Necroptosis / drug effects; Signal Transduction / drug effects; Swine; Trichothecenes / toxicity
TL;DR: It is suggested that EPA and DHA prevent DON‐induced intestinal cell injury and enhance barrier function, which is associated with inhibition of the necroptosis signaling pathway. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: January 6, 2020

2019 journal article

EPA and DHA inhibit myogenesis and downregulate the expression of muscle-related genes in C2C12 myoblasts

Genes, 10(1). http://www.scopus.com/inward/record.url?eid=2-s2.0-85060817194&partnerID=MN8TOARS

By: J. Zhang, X. Xu, Y. Liu, L. Zhang, J. Odle, X. Lin, H. Zhu, X. Wang, Y. Liu

Contributors: J. Zhang, X. Xu, Y. Liu, L. Zhang, J. Odle, X. Lin, H. Zhu, X. Wang, Y. Liu

Source: ORCID
Added: December 3, 2020

2019 speech

Enhancing Piglet Vitality with Bioactive Nutrients

Presented at the Zinpro Company (USA) sponsored International Trace Mineral Nutrition Symposium, Yokohama, Japan.

By: J. Odle

Event: Zinpro Company (USA) sponsored International Trace Mineral Nutrition Symposium at Yokohama, Japan on September 4, 2019

Source: NC State University Libraries
Added: February 26, 2022

2019 conference paper

Immunosuppressive effects of PRRS virus are dampened in alveolar macrophages from arachidonate-fed piglets

North American PRRS Symposium, 41.

By: K. Walter, T. Käser, X. Lin, D. Esposito & J. Odle

Event: North American PRRS Symposium at Chicago, IL

Source: NC State University Libraries
Added: February 26, 2022

2019 conference paper

Immunosuppressive effects of porcine reproductive and respiratory syndrome virus are dampened in porcine alveolar macrophages from arachidonate fed piglets

Presented at the Comparative Medicine Institute TPP Research Symposium, Raleigh, NC.

By: K. Walter, T. Käser, X. Lin, J. Odle & D. Esposito

Event: Comparative Medicine Institute TPP Research Symposium at Raleigh, NC on May 2, 2019

Source: NC State University Libraries
Added: February 26, 2022

2019 conference paper

Influence of dietary prebiotics and arachidonic acid on development of the fecal microbiome of pigs fed milk replacer

Jacobi, S., Lin, X., Maltecca, C., Walter, K. R., Smith, A., Fellner, V., & Odle, J. (2019, August 28). Presented at the BASF-NCSU MSA Symposium.

By: S. Jacobi, X. Lin, C. Maltecca, K. Walter, A. Smith, V. Fellner, J. Odle

Event: BASF-NCSU MSA Symposium on August 28, 2019

Source: NC State University Libraries
Added: February 26, 2022

2019 journal article

Mo1108 – Rescue of Restitution Defect in a Neonatal Pig Intestinal Ischemia Model is Associated with a Developing Enteric Glial Network

Gastroenterology, 156(6), S-709.

By: A. Ziegler, T. Pridgen, J. Odle*, L. Van Landeghem, S. Magness & A. Blikslager

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2. Zero Hunger (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 20, 2022

2019 journal article

Oesophageal eosinophilia accompanies food allergy to hen egg white protein in young pigs

Clinical & Experimental Allergy, 50(1), 95–104.

author keywords: animal model; eosinophil; esophagitis; food allergy; swine
MeSH headings : Animals; CD4-Positive T-Lymphocytes / immunology; Colon / immunology; Colon / pathology; Diarrhea / physiopathology; Disease Models, Animal; Egg Hypersensitivity / immunology; Egg Hypersensitivity / pathology; Egg Hypersensitivity / physiopathology; Egg Proteins / immunology; Endoscopy, Digestive System; Eosinophilic Esophagitis / immunology; Eosinophilic Esophagitis / pathology; Eosinophils / immunology; Eosinophils / pathology; Esophagus / immunology; Esophagus / pathology; Exanthema / physiopathology; Food Hypersensitivity / pathology; Ileum / immunology; Ileum / pathology; Immunophenotyping; Ovalbumin / immunology; Sus scrofa; Vomiting / physiopathology
TL;DR: Esophagitis with eosinophilia, inflammation, and fibrosis represent a chronic condition in humans with food allergies. (via Semantic Scholar)
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Sources: ORCID, Crossref, NC State University Libraries
Added: November 27, 2019

2019 journal article

PSV-11 Effects of plasma protein on growth performance and intestinal health of weaned pigs

Journal of Animal Science, 97(Supplement_2), 197–197.

By: G. Martinez Padilla n, Y. Silva-Guillen n, K. Moran n, X. Lin n, J. Odle n & E. Heugten n

author keywords: plasma protein; performance; cytokines
TL;DR: It is suggested that PP was not effective in improving overall growth performance and had minimal effects on intestinal health of weanling pigs. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 12, 2019

2019 conference paper

Suckling piglets have a rescuable defect in intestinal barrier repair associated with an immature enteric glial network

Presented at the Conference on Research Workers in Animal Diseases (CRWAD), Chicago, IL.

By: A. Ziegler, T. Pridgen, A. Sheridan, J. Odle, S. Magness, L. Van Landeghem, A. Blikslager

Event: Conference on Research Workers in Animal Diseases (CRWAD) at Chicago, IL

Source: NC State University Libraries
Added: February 26, 2022

2019 conference paper

The pig - A novel translational animal model for eosinophilic esophagitis

Proceedings of the International Veterinary Immunology Symposium, 60.

By: N. Plundrich, A. Smith, L. Borst, L. Edwards, T. Pridgen, L. Cortes, J. Odle, A. Blikslager ...

Event: International Veterinary Immunology Symposium at Seattle, WA on August 15, 2019

Source: NC State University Libraries
Added: February 26, 2022

2018 journal article

Epithelial restitution defect in neonatal jejunum is rescued by juvenile mucosal homogenate in a pig model of intestinal ischemic injury and repair

PLOS ONE, 13(8), e0200674.

By: A. Ziegler n, T. Pridgen n, J. Mills n, L. Gonzalez n, L. Van Landeghem n, J. Odle n, A. Blikslager n

Contributors: A. Ziegler n, T. Pridgen n, J. Mills n, L. Gonzalez n, L. Van Landeghem n, J. Odle n, A. Blikslager n

Ed(s): J. Karhausen

MeSH headings : Animals; Animals, Newborn; Cells, Cultured; Epithelium / injuries; Epithelium / pathology; Intestinal Diseases / physiopathology; Intestinal Mucosa / cytology; Intestinal Mucosa / physiology; Ischemia / physiopathology; Jejunum / injuries; Jejunum / physiology; Recovery of Function; Swine; Vascular Diseases / pathology; Vascular Diseases / prevention & control
TL;DR: Findings support the hypothesis that a defect in mucosal repair in neonates is due to immature repair mechanisms within the mucosal compartment, and ex vivo exogenous application of injured juvenile mucosal homogenate produced a significant increase in TEER and enhanced histological restitution. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: October 16, 2018

2018 magazine article

Feeding long chain polyunsaturated fatty acids to lactating sows to improve intestinal health of piglets

Van Heugten, E., Chang, P., & Odle, J. (2018, June 14). National Hog Farmer Magazine. https://www.nationalhogfarmer.com/nutrition/feeding-lcpufa-lactating-sows-improves-intestinal-health-piglets

By: E. Van Heugten, P. Chang & J. Odle

Source: NC State University Libraries
Added: March 19, 2022

2018 speech

Getting Your Manuscript Published: Practical Tips for Preparing Your Manuscript

Odle, J., & Davis, T. (2018, June). Presented at the ASN Annual Meeting, Boston, MA.

By: J. Odle & T. Davis

Event: ASN Annual Meeting at Boston, MA on June 11, 2018

Source: NC State University Libraries
Added: April 2, 2022

2018 journal article

Implementation Science in the Field of Nutrition: Why Is It So Relevant?

Current Developments in Nutrition, 3(3).

By: R. Pérez-Escamilla* & J. Odle n

Contributors: R. Pérez-Escamilla* & J. Odle n

TL;DR: Author disclosures: RP-E is currently funded with grants from the NIH, the Bill & Melinda Gates Foundation, the Family Larsson-Rosenquist foundation, the Kellogg Foundation, and the US Agency for International Development. (via Semantic Scholar)
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5. Gender Equality (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: April 9, 2019

2018 speech

Improving Fat Nutriture of the Perinate: Dietary Lipid Effects on GI Development in Postnatal Piglets

Odle, J. (2018, June). Presented at the Alcresta research meeting, Memphis, TN.

By: J. Odle

Event: Alcresta research meeting at Memphis, TN on June 19, 2018

Source: NC State University Libraries
Added: April 2, 2022

2018 conference paper

Influence of dietary prebiotics and arachidonic acid on development of the fecal microbiome of pigs fed milk replacer

Presented at the Digestive Physiology of Pigs Conference, Brisbane, Australia.

By: S. Jacobi, E. Chucta, X. Lin, C. Maltecca, K. Walter, A. Smith, V. Fellner, J. Odle

Event: Digestive Physiology of Pigs Conference at Brisbane, Australia on August 23, 2018

Source: NC State University Libraries
Added: April 2, 2022

2018 conference paper

Nutritional regulation of piglet gut health

Proceedings of the 18th Midwest Swine Nutrition Conference, 33–37.

By: S. Jacobi, E. Chucta, A. Taylor & J. Odle

Event: 18th Midwest Swine Nutrition Conference on September 6, 2018

Source: NC State University Libraries
Added: February 26, 2022

2018 journal article

Pharmacologic activation of peroxisome proliferator-activating receptor-α accelerates hepatic fatty acid oxidation in neonatal pigs

Oncotarget, 9(35), 23900–23914.

By: K. Shim n, S. Jacobi n, J. Odle n & X. Lin n

Contributors: K. Shim n, S. Jacobi n, J. Odle n & X. Lin n

TL;DR: Although the induction patterns of CPTI, MCD, ACO, KetoACoA, and ACCβ are different during the early postnatal period, 4 days of exposure to clofibrate were sufficient to robustly accelerate fatty acid oxidation. (via Semantic Scholar)
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3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: December 3, 2020

2018 journal article

Porcine alveolar macrophages enriched with LC-PUFA display modified cytokine gene expression and PGE2 production following PRRSV infection

Current Developments in Nutrition, 2, E13–05.

By: K. Walter, X. Lin, S. Jacobi, D. Esposito & J. Odle

Source: NC State University Libraries
Added: April 2, 2022

2018 conference paper

Porcine alveolar macrophages enriched with LC-PUFA modified inflammatory response to bacterial and viral stimulation

Presented at the New York Academy of Sciences STEM Exchange: Research and Career Symposium.

By: K. Walter, T. Käser, D. Esposito & J. Odle

Event: New York Academy of Sciences STEM Exchange: Research and Career Symposium

Source: NC State University Libraries
Added: April 2, 2022

2018 journal article

PubMed Central Archiving: A Major Milestone for Current Developments in Nutrition

Current Developments in Nutrition, 2(11).

By: J. Odle n

Contributors: J. Odle n

TL;DR: Current Developments in Nutrition (CDN) has been approved for inclusion in PubMed Central, which rapidly achieved milestone codifies the health and vitality of the Journal. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: December 31, 2018

2018 speech

Review and Evaluation of Current Developments in Nutrition: Editor-in-Chief Report to Am. Soc. Nutr. and CDN editors

Odle, J. (2018, June). Presented at the ASN Annual Meeting, Boston, MA.

By: J. Odle

Event: ASN Annual Meeting at Boston, MA on June 8, 2018

Source: NC State University Libraries
Added: April 2, 2022

2017 journal article

399 Prophylactic enrichment of sow milk and intestinal mucosa of piglets by supplementation of arachidonic and eicosapentaenoic acid to sows during lactation

Journal of Animal Science, 95(suppl_4), 197–197.

By: P. Chang n, J. Odle n & E. van Heugten n

author keywords: intestinal enrichment; long-chain polyunsaturated fatty acids; sows
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2. Zero Hunger (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 26, 2022

2017 journal article

Activation of PPARα by Oral Clofibrate Increases Renal Fatty Acid Oxidation in Developing Pigs

International Journal of Molecular Sciences, 18(12), 2663.

By: Y. He n, I. Khan n, X. Bai n, J. Odle n & L. Xi n

Contributors: Y. He n, I. Khan n, X. Bai n, J. Odle n & L. Xi n

author keywords: peroxisome proliferator-activated receptor alpha (PPAR alpha); clofibrate; fatty acid beta-oxidation; pigs
MeSH headings : 3-Hydroxybutyric Acid / biosynthesis; Animals; Clofibrate / administration & dosage; Fatty Acids / biosynthesis; Fatty Acids / genetics; Hydroxymethylglutaryl-CoA Synthase / biosynthesis; Kidney / drug effects; Kidney / metabolism; Lipid Metabolism / genetics; Mitochondria / genetics; Mitochondria / metabolism; Oxidation-Reduction; PPAR alpha / genetics; Peroxisomes / genetics; Peroxisomes / metabolism; Swine
TL;DR: It is found that PPARα activation stimulates renal fatty acid oxidation but not ketogenesis, and the mRNA abundance and enzyme activity of carnitine palmitoyltransferase I in mitochondria were increased. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2017 speech

Animal Food & Nutrition Consortium: The NCSU Swine Nutrition Team

Odle, J. (2017, September). Animal Food & Nutrition Consortium: The NCSU Swine Nutrition Team. Presented at the Biotechnology Center, Research Triangle Park, NC.

By: J. Odle

Event: Biotechnology Center at Research Triangle Park, NC on September 29, 2017

Source: NC State University Libraries
Added: April 2, 2022

2017 report

Creation of the Draft Global Animal Nutrition Network

[Website].

By: G. Cromwell, T. Applegate, D. Beitz, M. Galyean, M. Hall, M. Hanigan, J. Odle, W. Weiss, C. Baer

Source: NC State University Libraries
Added: February 26, 2022

2017 journal article

Current Developments in Nutrition: A New Journal Designed for the Open-Access Era

Current Developments in Nutrition, 1(1), e000001.

By: J. Odle n

Contributors: J. Odle n

TL;DR: The introduction of Current Developments in Nutrition, the most recent addition to the ASN family of journals serving the worldwide nutrition community, is introduced. (via Semantic Scholar)
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Added: August 6, 2018

2017 speech

Current Developments in Nutrition: Bridging Nutrition and Food Science

Odle, J. (2017, June). Presented at the Institute for Food Technologists preconference, Las Vegas, NV.

By: J. Odle

Event: Institute for Food Technologists preconference at Las Vegas, NV on June 24, 2017

Source: NC State University Libraries
Added: April 3, 2022

2017 journal article

Dietary Prebiotics and Arachidonic Acid (ARA) Modulate Intestinal Injury and Microbial Taxa Following Acute Dextran Sodium Sulfate Induced Colitis in Formula‐Fed Piglets

The FASEB Journal, 31(S1).

TL;DR: In conclusion supplementation of formula with prebiotics significantly shifts microbial taxa on d22, modulates intestinal pH, and laxation, and main effects of diet and DSS on epithelial damage, lamina propria inflammation, crypt abscess, crypt dropout, and overall colitis score are shown. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 20, 2022

2017 journal article

Dietary long-chain PUFAs enrich porcine alveolar macrophages and alter Prostaglandin E-2 Production Following LPS Challenge

FASEB Journal, 31.

By: K. Walter, L. Xi, S. Jacobi, D. Esposito & J. Odle

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Dietary long-chain PUFAs enrich porcine alveolar macrophages and modulate inflammatory response

In Vitro Cellular & Developmental Biology - Animal, 53(Suppl. 1), S20–S21.

By: K. Walter, L. Xi, S. Jacobi, D. Esposito & J. Odle

Source: NC State University Libraries
Added: April 2, 2022

2017 journal article

Dietary prebiotics and arachidonic acid alter intestinal phospholipid composition and time-dependently change fecal microbiome in formula-fed piglets

FASEB Journal, 31.

By: M. Thorpe, L. Xi, C. Maltecca, K. Walters, A. Smith, J. Odle, S. Jacobi

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Effect of Medium Chain Triglycerides on TCA and Ketogenic Capacity of Proximal Intestinal Fatty Acid Oxidation in Clofibrate Feed Newborn Pigs

The FASEB Journal, 31(S1).

By: B. Pike n, J. Zhao n, J. Hicks n, Y. Zhang n, A. Smith n, H. Liu n, J. Odle n, L. Xi n

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7. Affordable and Clean Energy (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 20, 2022

2017 article

Effect of dietary manganese on antioxidant status and expressions of heat shock proteins and factors in tissues of laying broiler breeders under normal and high environmental temperatures (Retraction of Vol 114, Pg 1965, 2015)

Zhu, Y.-W., Lu, L., Li, W.-X., Zhang, L.-Y., Ji, C., Lin, Xi, … Luo, X.-G. (2018, January 14). BRITISH JOURNAL OF NUTRITION, Vol. 119, pp. 117–117.

By: Y. Zhu*, L. Lu*, W. Li*, L. Zhang*, C. Ji*, . Lin n, H. Liu n, J. Odle n, X. Luo*

Contributors: Y. Zhu*, L. Lu*, W. Li*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2017 journal article

Effects of Dietary Anaplerotic Carbon Sources and Ketogenic Fatty Acids on Hepatic Fatty Acid Oxidation in Neonatal Pigs

The FASEB Journal, 31(S1).

By: J. Zhao n, B. Pike n, Y. Zhang n, S. Sabin n, A. Smith n, Y. Zhu n, J. Odle n, L. Xi n

Sources: Crossref, NC State University Libraries
Added: February 20, 2022

2017 speech

Effects of prebiotics and ARA in a piglet model of colitis. NIFA-AFRI Project Director’s update

Odle, J. (2017, June). Presented at the IFT, Las Vegas, NV.

By: J. Odle

Event: IFT at Las Vegas, NV on June 24, 2017

Source: NC State University Libraries
Added: April 2, 2022

2017 speech

Enhancing Collaboration to Accelerate Agricultural Advancement

Odle, J. (2017, October). Presented at the National Academies of Science. Science Breakthroughs, Irvine, CA.

By: J. Odle

Event: National Academies of Science. Science Breakthroughs at Irvine, CA on October 1, 2017

Source: NC State University Libraries
Added: April 3, 2022

2017 speech

Getting Your Manuscript Published: Practical Tips for Preparing Your Manuscript, Avoiding Common Mistakes, and Choosing the Right Journal

Odle, J. (2017, October). Presented at the International Union of Nutritional Sciences, Buenos Aires, Argentina.

By: J. Odle

Event: International Union of Nutritional Sciences at Buenos Aires, Argentina on October 15, 2017

Source: NC State University Libraries
Added: April 3, 2022

2017 speech

How does the proposed Animal Food & Nutrition Consortium fit into the larger Food-Animal Initiative and Food-Animal Academy?

Odle, J. (2017, February). How does the proposed Animal Food & Nutrition Consortium fit into the larger Food-Animal Initiative and Food-Animal Academy? Presented at the College of Agriculture & Life Sciences, Raleigh, NC.

By: J. Odle

Event: College of Agriculture & Life Sciences at Raleigh, NC on February 7, 2017

Source: NC State University Libraries
Added: April 2, 2022

2017 journal article

Impact of maternal heat stress in conjunction with dietary zinc supplementation on hatchability, embryonic development, and growth performance in offspring broilers

Poultry Science, 96(7), 2351–2359.

By: Y. Zhu*, W. Li*, L. Lu*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

Contributors: Y. Zhu*, W. Li*, L. Lu*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

author keywords: chick embryo; growth performance; maternal heat stress; offspring; zinc
MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena / drug effects; Animals; Chick Embryo; Chickens / growth & development; Chickens / physiology; Diet / veterinary; Dietary Supplements / analysis; Embryonic Development / drug effects; Female; Hot Temperature / adverse effects; Male; Random Allocation; Reproduction / drug effects; Zinc / administration & dosage; Zinc / metabolism
TL;DR: It is indicated that maternal heat stress impairs hatching performance, embryonic development, and progeny growth performance, inducing metabolic changes, while supplementation of Zn in maternal diets regardless of ZN sources improved hatch chick quality and survivability of offspring and alleviated the negative effect of maternalHeat stress on growth performance of offspring during the starter period. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2017 conference paper

Introducing Current Developments in Nutrition to Experimental Biologists

Odle, J. (2017, April 22). Presented at the FASEB Conference, Chicago, IL.

By: J. Odle

Event: FASEB Conference at Chicago, IL on April 22-26, 2017

Source: NC State University Libraries
Added: April 3, 2022

2017 journal article

Maternal dietary manganese protects chick embryos against maternal heat stress via epigenetic-activated antioxidant and anti-apoptotic abilities

Oncotarget, 8(52), 89665–89680.

By: Y. Zhu*, L. Lu*, X. Liao*, W. Li*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n ...

Contributors: Y. Zhu*, L. Lu*, X. Liao*, W. Li*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

author keywords: epigenetics; maternal environmental hyperthermia; manganese superoxide dismutase; apoptosis; chick embryo
TL;DR: It is suggested that maternal dietary manganese addition could protect the chick embryonic development against maternal heat stress via enhancing epigenetic-activated antioxidant and anti-apoptotic abilities. (via Semantic Scholar)
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2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2017 journal article

Maternal dietary zinc supplementation enhances the epigenetic-activated antioxidant ability of chick embryos from maternal normal and high temperatures

Oncotarget, 8(12), 19814–19824.

By: Y. Zhu*, X. Liao*, L. Lu*, W. Li*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n ...

Contributors: Y. Zhu*, X. Liao*, L. Lu*, W. Li*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

author keywords: epigenetics; maternal hyperthermia; zinc; metallothionein; chick embryo
MeSH headings : Acetylation / drug effects; Animal Nutritional Physiological Phenomena; Animals; Antioxidants / metabolism; Avian Proteins / genetics; Avian Proteins / metabolism; Blotting, Western; Chick Embryo; Chickens; DNA Methylation / drug effects; Dietary Supplements; Epigenesis, Genetic / drug effects; Female; Gene Expression Regulation, Developmental / drug effects; Heat-Shock Proteins / genetics; Heat-Shock Proteins / metabolism; Histones / metabolism; Hot Temperature; Liver / drug effects; Liver / embryology; Liver / metabolism; Lysine / metabolism; Metallothionein / genetics; Metallothionein / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Zinc / administration & dosage; Zinc / pharmacology
TL;DR: It is demonstrated that maternal dietary zinc addition as an epigenetic modifier could protect the offspring embryonic development against maternal heat stress via enhancing the epigenetic-activated antioxidant ability. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2017 report

NC State’s Global Food Animal Initiative: Establishing North Carolina as the world leader in food animal biosciences

[Infographic white paper]. Raleigh, NC: North Carolina State University.

By: J. Odle, C. Brown., J. Brumfield, M. Quinlan & C. Sandy

Source: NC State University Libraries
Added: February 26, 2022

2017 speech

Review and Evaluation of Current Developments in Nutrition: Editor-in-Chief Report to Am. Soc. Nutr. and CDN editors.

Odle, J. (2017, April). Editor-in-Chief Report to presented at the ASN Annual Meeting, Chicago, IL.

By: J. Odle

Event: ASN Annual Meeting at Chicago, IL on April 21, 2017

Source: NC State University Libraries
Added: April 2, 2022

2017 journal article

Supplementation of Maternal Diets with Docosahexaenoic Acid and Methylating Vitamins Impacts Growth and Development of Fetuses from Malnourished Gilts

Current Developments in Nutrition, 2(3).

By: H. Lima n, X. Lin n, S. Jacobi n, C. Man n, J. Sommer n, W. Flowers n, A. Blikslager n, L. Gonzalez n, J. Odle n

Contributors: H. Lima n, X. Lin n, S. Jacobi n, C. Man n, J. Sommer n, W. Flowers n, A. Blikslager n, L. Gonzalez n, J. Odle n

author keywords: choline; B-vitamins; epigenetics; intrauterine growth restriction; nutrient restriction; low birth weight
TL;DR: Despite the mobilization of maternal stores, malnourished litters displayed reduced brain development that was fully mitigated by micronutrient supplementation. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: August 6, 2018

2017 review

The Potential Impact of Animal Science Research on Global Maternal and Child Nutrition and Health: A Landscape Review

[Review of ]. ADVANCES IN NUTRITION, 8(2), 362–381.

By: J. Odle n, S. Jacobi*, R. Boyd n, D. Bauman*, R. Anthony*, F. Bazer*, A. Lock*, A. Serazin*

Contributors: J. Odle n, S. Jacobi*, R. Dean Boyd, D. Bauman*, R. Anthony*, F. Bazer*, A. Lock*, A. Serazin*

author keywords: global health; growth stunting; animal models; pregnancy; lactation; fatty acids; amino acids; zinc; iron; phytase
MeSH headings : Agriculture; Animals; Animals, Newborn; Child Health; Databases, Factual; Diet; Dietary Proteins / administration & dosage; Female; Humans; Lactation; Maternal Health; Maternal Nutritional Physiological Phenomena; Nutritional Status; Nutritive Value; Pregnancy; Trace Elements / administration & dosage; Vitamins / administration & dosage; Weaning
TL;DR: This landscape review was commissioned by the Bill & Melinda Gates Foundation to examine the nutritional and managerial practices used within the food-animal agricultural system that may have relevance to the challenges faced by global human health. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2017 article

What global maternal and child nutrition can learn from animal science

Victora, C. G., Martorell, R., Ganapathi, S., Boyd, R. D., Bauman, D. E., & Odle, J. (2017, August). LANCET GLOBAL HEALTH, Vol. 5, pp. E749–E751.

By: C. Victora*, R. Martorell*, S. Ganapathi*, R. Boyd n, D. Bauman* & J. Odle n

Contributors: C. Victora*, R. Martorell*, S. Ganapathi*, R. Boyd n, D. Bauman* & J. Odle n

MeSH headings : Animal Nutrition Sciences; Animals; Child Nutrition Disorders / prevention & control; Child Nutritional Physiological Phenomena; Child, Preschool; Developing Countries; Female; Global Health; Humans; Infant; Maternal Nutritional Physiological Phenomena; Pregnancy
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
1. No Poverty (Web of Science)
2. Zero Hunger (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2016 journal article

784 Neonates Have a Reduced Ability to Repair Jejunal Mucosal Injury As Compared to Juveniles in a Pig Model of Ischemia/ Reperfusion Injury

Gastroenterology, 150(4), S163.

By: A. Ziegler, T. Pridgen, G. Carnighan, J. Odle* & A. Blikslager*

Sources: Crossref, NC State University Libraries
Added: January 25, 2020

2016 journal article

Asparagine improves intestinal integrity, inhibits TLR4 and NOD signaling, and differently regulates p38 and ERK1/2 signaling in weanling piglets after LPS challenge

Innate Immunity, 22(8), 577–587.

By: S. Chen*, Y. Liu*, X. Wang*, H. Wang*, S. Li*, H. Shi*, H. Zhu*, J. Zhang* ...

Contributors: S. Chen*, Y. Liu*, X. Wang*, H. Wang*, S. Li*, H. Shi*, H. Zhu*, J. Zhang* ...

author keywords: Asparagine; weanling piglets; intestine; lipopolysaccharide; inflammatory response
MeSH headings : Animals; Anti-Inflammatory Agents / pharmacology; Apoptosis / drug effects; Asparagine / pharmacology; Caspase 3 / metabolism; Cell Proliferation / drug effects; Cells, Cultured; Cytokines / metabolism; Enterocytes / drug effects; Enterocytes / physiology; Enzyme Inhibitors / pharmacology; Inflammation / drug therapy; Inflammation Mediators / metabolism; Intestinal Mucosa / immunology; Intestinal Mucosa / pathology; Lipopolysaccharides / immunology; MAP Kinase Signaling System / drug effects; Ornithine Decarboxylase / metabolism; Oxygenases / metabolism; Phosphorylation / drug effects; Swine; Toll-Like Receptor 4 / metabolism; Weaning; p38 Mitogen-Activated Protein Kinases / metabolism
TL;DR: The results suggest that Asn improves intestinal integrity during an inflammatory insult, which appears to be related to the decrease of intestinal pro-inflammatory cytokine and of enterocyte apoptosis (via p38 and ERK1/2). (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Asparagine reduces the mRNA expression of muscle atrophy markers via regulating protein kinase B (Akt), AMP-activated protein kinase α, toll-like receptor 4 and nucleotide-binding oligomerisation domain protein signalling in weaning piglets after lipopolysaccharide challenge

British Journal of Nutrition, 116(7), 1188–1198.

By: X. Wang*, Y. Liu*, S. Wang*, D. Pi*, W. Leng*, H. Zhu*, J. Zhang*, H. Shi* ...

Contributors: X. Wang*, Y. Liu*, S. Wang*, D. Pi*, W. Leng*, H. Zhu*, J. Zhang*, H. Shi* ...

author keywords: Asparagine; Lipopolysaccharides; Muscle atrophy; Pro-inflammatory cytokines
MeSH headings : AMP-Activated Protein Kinases / antagonists & inhibitors; AMP-Activated Protein Kinases / metabolism; Animals; Asparagine / pharmacology; Enzyme Activation / drug effects; F-Box Proteins / analysis; F-Box Proteins / genetics; Forkhead Box Protein O1 / antagonists & inhibitors; Gene Expression / drug effects; Lipopolysaccharides / pharmacology; Muscle Proteins / metabolism; Muscle, Skeletal / chemistry; Muscular Atrophy / chemically induced; Muscular Atrophy / genetics; Nod Signaling Adaptor Proteins / antagonists & inhibitors; Phosphorylation / drug effects; Polycomb Repressive Complex 1 / analysis; Polycomb Repressive Complex 1 / genetics; Proto-Oncogene Proteins c-akt / metabolism; RNA, Messenger / analysis; Signal Transduction / drug effects; Sus scrofa; Toll-Like Receptor 4 / genetics; Toll-Like Receptor 4 / metabolism; Weaning
TL;DR: The beneficial effects of Asn on muscle atrophy may be associated with inhibiting muscle protein degradation via activating Akt and inactivating AMPKα and FOXO1; and decreasing the expression of muscle pro-inflammatory cytokines via inhibiting TLR4 and NOD signalling pathways by modulation of their negative regulators. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2016 conference paper

Collaborative food-animal nutrition research: update and critique

Odle, J. (2016, September 29). Presented at the Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, CN.

By: J. Odle

Event: Institute of Animal Science, Chinese Academy of Agricultural Sciences at Beijing, CN on September 29, 2016

Source: NC State University Libraries
Added: April 3, 2022

2016 speech

Current Developments in Nutrition: Orientation and of Deputy Editors

Odle, J. (2016, November). Presented at the American Society of Nutrition, Rockville, MD.

By: J. Odle

Event: American Society of Nutrition at Rockville, MD on November 11, 2016

Source: NC State University Libraries
Added: April 3, 2022

2016 journal article

Effect of dietary manganese on antioxidant status and expressions of heat shock proteins and factors in tissues of laying broiler breeders under normal and high environmental temperatures

British Journal of Nutrition, 116(11), 1851–1860.

By: Y. Zhu*, L. Lu*, W. Li*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

Contributors: Y. Zhu*, L. Lu*, W. Li*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

author keywords: Broiler breeders; Manganese; Heat stress; Antioxidant status; Heat shock proteins/factors
MeSH headings : Animals; Avian Proteins / genetics; Avian Proteins / metabolism; Biomarkers / metabolism; Chelating Agents / administration & dosage; Chickens / growth & development; Chickens / physiology; China; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; Diet / veterinary; Female; Gene Expression Regulation, Developmental; HSP70 Heat-Shock Proteins / genetics; HSP70 Heat-Shock Proteins / metabolism; Heart Ventricles / enzymology; Heart Ventricles / growth & development; Heart Ventricles / metabolism; Heat Shock Transcription Factors; Heat-Shock Proteins / genetics; Heat-Shock Proteins / metabolism; Heat-Shock Response; Intestinal Absorption; Liver / enzymology; Liver / growth & development; Liver / metabolism; Manganese / administration & dosage; Manganese / metabolism; Manganese Compounds / administration & dosage; Muscle, Skeletal / enzymology; Muscle, Skeletal / growth & development; Muscle, Skeletal / metabolism; Oxidative Stress; RNA, Messenger / metabolism; Random Allocation; Sulfates / administration & dosage; Trans-Activators / genetics; Trans-Activators / metabolism; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR: It is indicated that high temperature decreases Mn retention and increases HSP70, HSF1 and HSF3 expressions in the tissues of laying broiler breeders and dietary supplementation with Mn in either source may enhance the heart’s antioxidant ability and inhibit the expression of HSP 70 in breast muscle. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2016 speech

Enhancing fatty acid oxidation in newborn pigs to improve survivability

Lin, X., & Odle, J. (2016, July). Presented at the USDA-NIFA Project Director’s Meeting, Salt Lake City, UT.

By: X. Lin & J. Odle

Event: USDA-NIFA Project Director’s Meeting at Salt Lake City, UT on July 23, 2016

Source: NC State University Libraries
Added: April 3, 2022

2016 journal article

Essential fatty acid supplementation during lactation is required to maximize the subsequent reproductive performance of the modern sow

ANIMAL REPRODUCTION SCIENCE, 168, 151–163.

By: D. Rosero n, R. Boyd n, M. McCulley, J. Odle n & E. Heugten n

Contributors: D. Rosero n, R. Boyd n, M. McCulley, J. Odle n & E. Heugten n

author keywords: Essential fatty acids; Lactation; Lipids; Sows; Subsequent reproduction
MeSH headings : Animals; Corn Oil / pharmacology; Diet / veterinary; Dietary Supplements; Fatty Acids, Essential / administration & dosage; Fatty Acids, Essential / pharmacology; Fatty Acids, Monounsaturated / pharmacology; Female; Lactation / drug effects; Lactation / physiology; Linoleic Acid / administration & dosage; Linoleic Acid / pharmacology; Linseed Oil / pharmacology; Pregnancy; Rapeseed Oil; Reproduction / drug effects; Reproduction / physiology; Swine / physiology; alpha-Linolenic Acid / pharmacology
TL;DR: It is demonstrated that a minimum dietary intake of both α-linolenic and linoleic acid is required for the modern lactating sow to achieve a maximum reproductive outcome through multiple mechanisms that include rapid return to estrus, increased maintenance of pregnancy and improved subsequent litter size. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2016 speech

NCSU Food Animal Academy Ideation Phase, Final Report

Odle, J. (2016, February). Presented at the Food Animal Administrative Coalition, Raleigh, NC.

By: J. Odle

Event: Food Animal Administrative Coalition at Raleigh, NC on February 19, 2016

Source: NC State University Libraries
Added: April 3, 2022

2016 speech

Nutritional biochemistry of bioactive fatty acids in young pigs

Odle, J. (2016, August). Presented at the Cargill Global Animal Nutrition Conference, Amsterdam, The Netherlands.

By: J. Odle

Event: Cargill Global Animal Nutrition Conference at Amsterdam, The Netherlands on August 28, 2016

Source: NC State University Libraries
Added: April 3, 2022

2016 review

Optimizing dietary lipid use to improve essential fatty acid status and reproductive performance of the modern lactating sow: a review

[Review of ]. JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY, 7(1).

By: D. Rosero, R. Boyd, J. Odle n & E. Heugten n

Contributors: D. Rosero, R. Dean Boyd, J. Odle n & E. Heugten n

author keywords: Essential fatty acids; Lactating sow; Subsequent reproduction; Supplemental lipids
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2016 speech

Panel Discussion on Career Paths in Agriculture

Odle, J. (2016, March). Presented at the Purdue College of Agriculture, Distinguished Alumni Program, West Lafayette, IN.

By: J. Odle

Event: Purdue College of Agriculture, Distinguished Alumni Program at West Lafayette, IN on March 4, 2016

Source: NC State University Libraries
Added: April 3, 2022

2015 book

A sublethal swine model for defining in vivo superantigen-induced responses following exposure to staphylococcal enterotoxin B

In Methods in Molecular Biology (Vol. 1396, pp. 115–124).

By: K. Bost*, K. Piller*, J. Odle n & C. Stahl n

Contributors: K. Bost*, K. Piller*, J. Odle n & C. Stahl n

author keywords: In vivo swine model; Superantigen; Sublethal challenge; Staphylococcal enterotoxin B; Cytokine analyses
MeSH headings : Animals; Disease Models, Animal; Enterotoxins / immunology; Inflammation Mediators / blood; Staphylococcal Infections / blood; Staphylococcal Infections / immunology; Staphylococcal Infections / microbiology; Staphylococcal Infections / mortality; Staphylococcus aureus / immunology; Superantigens / immunology; Swine
TL;DR: In vivo responses to bacterially derived superantigen-like toxins have been difficult to define due to the inherent limitations with rodent models and the relevance that the results obtained from such models may, or may not, have for human pathophysiology, so this model utilizes thesuperantigen, staphylococcal enterotoxin B, at doses that are sublethal in a swine model of toxin-induced incapacitation. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
Source: ORCID
Added: November 19, 2019

2015 journal article

Acute Dextran Sodium Sulfate Dose‐Dependently Induces Colitis in Formula‐Fed Piglets

The FASEB Journal, 29(S1).

UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 20, 2022

2015 speech

Advancing global maternal and infant health via insights gleaned from research in agricultural species

Odle, J. (2015, January). Introduction presented at the Gates Foundation Convening, DH Hill Library, Raleigh, NC.

By: J. Odle

Event: Gates Foundation Convening at DH Hill Library, Raleigh, NC on January 15, 2015

Source: NC State University Libraries
Added: April 3, 2022

2015 speech

Advancing global maternal and infant health via insights gleaned from research in agricultural species. Lactation/suckling phase.

Odle, J. (2015, January). Presented at the Gates Foundation Convening, DH Hill Library, Raleigh, NC.

By: J. Odle

Event: Gates Foundation Convening at DH Hill Library, Raleigh, NC on January 15, 2015

Source: NC State University Libraries
Added: April 3, 2022

2015 journal article

Apparent balance of essential fatty acids for the prolific lactating sow

Journal of Animal Science, 93(Suppl 2), 76.

By: D. Rosero, J. Odle, R. Boyd & E. van Heugten

Event: Midwestern Section Animal Science Meetings at Des Moines, IA

Source: NC State University Libraries
Added: April 3, 2022

2015 report

Defining Animal Nutrition Research Priorities for a Healthy Society

[Brochure]. National Animal Nutrition Program Summit.

By: R. White, T. Applegate, G. Cromwell, D. Beitz, M. Galyean, M. Hall, P. Miller, J. Odle, W. Weiss, M. Hanigan

Source: NC State University Libraries
Added: April 3, 2022

2015 speech

Defining Animal Nutrition Research Priorities for a Healthy Society: Human and Animal Health

Odle, J. (2015, March). Moderated panel presented at the National Animal Nutrition Program Summit, National Press Club, Washington DC. https://www.youtube.com/watch?v=KID-nAe6lW0FA

By: J. Odle

Event: National Animal Nutrition Program Summit at National Press Club, Washington DC on March 25, 2015

Source: NC State University Libraries
Added: April 3, 2022

2015 journal article

Development of prediction equations to estimate the apparent digestible energy content of lipids when fed to lactating sows

JOURNAL OF ANIMAL SCIENCE, 93(3), 1165–1176.

By: D. Rosero, J. Odle*, C. Arellano n, R. Boyd* & E. Heugten

Contributors: D. Rosero, J. Odle*, C. Arellano n, R. Boyd* & E. Heugten

author keywords: digestibility; free fatty acids; lactating sow; lipid saturation; prediction equation
MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena / physiology; Animals; Diet / veterinary; Dietary Fats / metabolism; Dietary Fats / pharmacology; Dietary Supplements; Digestion / physiology; Energy Metabolism / drug effects; Energy Metabolism / physiology; Fatty Acids, Nonesterified / metabolism; Fatty Acids, Nonesterified / pharmacology; Female; Lactation / physiology; Lipid Metabolism / drug effects; Lipid Metabolism / physiology; Models, Biological; Models, Statistical; Swine / physiology
TL;DR: The proposed equation involving FFA concentration and U:S resulted in highly accurate estimations of DE content (relative error, +0.2 to -2.3%) of commercial sources of lipids for lactating sows. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Development of prediction equations to estimate the apparent digestible energy content of lipids when fed to lactating sows

Journal of Animal Science, 93(3), 1165–1176.

By: D. Rosero, J. Odle, C. Arellano, R. Boyd & E. Heugten

Contributors: D. Rosero, J. Odle, C. Arellano, R. Boyd & E. Heugten

Source: ORCID
Added: November 19, 2019

2015 journal article

Dietary Isomers of Sialyllactose Increase Ganglioside Sialic Acid Concentrations in the Corpus Callosum and Cerebellum and Modulate the Colonic Microbiota of Formula-Fed Piglets

JOURNAL OF NUTRITION, 146(2), 200–208.

By: S. Jacobi n, T. Yatsunenko*, D. Li*, S. Dasgupta*, R. Yu*, B. Berg*, M. Chichlowski*, J. Odle n

Contributors: S. Jacobi n, T. Yatsunenko*, D. Li*, S. Dasgupta*, R. Yu*, B. Berg*, M. Chichlowski*, J. Odle n

author keywords: oligosaccharides; infant formula; microbiome; intestine; brain; prebiotic
MeSH headings : Animals; Bacteria / growth & development; Brain / drug effects; Brain / metabolism; Cerebellum / drug effects; Cerebellum / metabolism; Colon / drug effects; Colon / microbiology; Corpus Callosum / drug effects; Corpus Callosum / metabolism; Diet; Dietary Supplements; Gangliosides / metabolism; Gastrointestinal Microbiome / drug effects; Infant Formula; Isomerism; Lactose / analogs & derivatives; Lactose / pharmacology; Milk, Human / chemistry; Oligosaccharides / pharmacology; Sialic Acids / pharmacology; Swine
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 article

Effect of dietary manganese on antioxidant status and expression levels of heat-shock proteins and factors in tissues of laying broiler breeders under normal and high environmental temperatures (Retracted article. See vol. 119, pg. 117, 2018)

Zhu, Y.-W., Lu, L., Li, W.-X., Zhang, L.-Y., Ji, C., Lin, Xi, … Luo, X.-G. (2015, December 28). BRITISH JOURNAL OF NUTRITION, Vol. 114, pp. 1965–1974.

By: Y. Zhu*, L. Lu*, W. Li*, L. Zhang*, C. Ji*, . Lin n, H. Liu n, J. Odle n, X. Luo*

Contributors: Y. Zhu*, L. Lu*, W. Li*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

author keywords: Broiler breeders; Manganese; Heat stress; Antioxidant status; Heat-shock proteins/factors
MeSH headings : Animals; Antioxidants / metabolism; Chickens; Diet; Female; Heat-Shock Proteins / genetics; Heat-Shock Proteins / metabolism; Hot Temperature; Liver / enzymology; Malondialdehyde / metabolism; Manganese / administration & dosage; Manganese / pharmacokinetics; Myocardium / enzymology; RNA / metabolism; Superoxide Dismutase / metabolism; Temperature; Tissue Distribution
TL;DR: The results indicate that high temperature decreases Mn retention and increases HSP70 and HSF1, HSF3 expression levels in tissues of laying broiler breeders, and dietary supplementation with Mn in either source may enhance heart antioxidant ability and inhibit the expression of HSP 70 in breast muscle. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Effects of acute and chronic heat stress on plasma metabolites, hormones and oxidant status in restrictedly fed broiler breeders

Poultry Science, 94(7), 1635–1644.

By: J. Xie*, L. Tang*, L. Lu*, L. Zhang*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

Contributors: J. Xie*, L. Tang*, L. Lu*, L. Zhang*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

author keywords: broiler breeder; heat stress; metabolite; hormone; oxidation
MeSH headings : Animals; Blood Chemical Analysis / veterinary; Chickens / physiology; Enzyme-Linked Immunosorbent Assay / veterinary; Female; Heat-Shock Response; Hormones / blood; Oxidants / metabolism; Radioimmunoassay / veterinary; Random Allocation
TL;DR: Taking together, acute heat stress primarily resulted in disturbance of plasma metabolites, whereas chronic heat stress caused tissue damage reflected by increased plasma LDA, GOT, and CK. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Effects of environmental temperature and dietary manganese on egg production performance, egg quality, and some plasma biochemical traits of broiler breeders

Journal of Animal Science, 93(7), 3431–3440.

By: Y. Zhu*, J. Xie, W. Li*, L. Lu*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

author keywords: broiler breeders; high temperature; laying performance; manganese; plasma biochemical traits
MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Chickens / physiology; Diet / veterinary; Dietary Supplements; Eggs / standards; Female; Lipid Peroxidation; Malondialdehyde / metabolism; Manganese / pharmacology; Oviposition / drug effects; Plasma; Protein Carbonylation; Soybeans / chemistry; Temperature
TL;DR: The results from this study indicated that high temperature significantly impaired egg production performance and eggshell quality and induced lipid peroxidation and tissue damage whereas dietary supplementation of either organic or inorganic Mn improved eggshell strength and thermotolerance and reduced protein oxidation and that the organic Mn could alleviate the negative effect of high temperature on eggProduction performance of broiler breeders at the period of 32 to 45 wk of age. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Effects of environmental temperature and dietary manganese on egg production performance, egg quality, and some plasma biochemical traits of broiler breeders

Journal of Animal Science, 93(7), 3431–3440.

By: Y. Zhu, J. Xie, W. Li, L. Lu, L. Zhang, C. Ji, X. Lin, H. Liu, J. Odle, X. Luo

Contributors: Y. Zhu, J. Xie, W. Li, L. Lu, L. Zhang, C. Ji, X. Lin, H. Liu, J. Odle, X. Luo

Source: ORCID
Added: November 19, 2019

2015 journal article

Effects of maternal dietary manganese and incubation temperature on hatchability, antioxidant status, and expression of heat shock proteins in chick embryos

Journal of Animal Science, 93(12), 5725–5734.

By: Y. Zhu*, L. Lu*, W. Li*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

author keywords: antioxidant status; chick embryo; heat shock protein; incubation temperatures; manganese
MeSH headings : Animal Feed / analysis; Animal Feed / standards; Animals; Antioxidants / metabolism; Body Weight; Chick Embryo / metabolism; Chick Embryo / physiology; Chickens / physiology; Diet / veterinary; Dietary Supplements; Egg Yolk / chemistry; Female; Heat-Shock Proteins / metabolism; Hot Temperature / adverse effects; Liver / embryology; Liver / enzymology; Liver / metabolism; Malondialdehyde / analysis; Manganese / administration & dosage; Manganese / analysis; Manganese / pharmacology; Maternal Nutritional Physiological Phenomena / physiology; Myocardium / enzymology; Random Allocation; Superoxide Dismutase / analysis; Superoxide Dismutase / genetics
TL;DR: Maternal dietary supplementation of Mn could improve the hatchability as well as antioxidant ability to protect against heat challenge in embryos during incubation, and indicated that high incubation temperature induced self-protective responses of chick embryos with a modification of antioxidant status and a depression of HSP70 protein level. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Effects of maternal dietary manganese and incubation temperature on hatchability, antioxidant status, and expression of heat shock proteins in chick embryos

Journal of Animal Science, 93(12), 5725–5734.

By: Y. Zhu, L. Lu, W. Li, L. Zhang, C. Ji, X. Lin, H. Liu, J. Odle, X. Luo

Contributors: Y. Zhu, L. Lu, W. Li, L. Zhang, C. Ji, X. Lin, H. Liu, J. Odle, X. Luo

Source: ORCID
Added: November 19, 2019

2015 conference paper

Effects of methylating vitamins and docosahexaenoic acid (DHA) supplementation on intra-uterine growth retardation (IUGR) in a feed-restricted swine model.

Presented at the NCSU Graduate Research Symposium, Raleigh, NC.

By: H. Lima, C. Jacobi, C. Man, K. Walker, J. Sommer, W. Flowers, A. Blikslager, X. Lin, J. Odle

Event: NCSU Graduate Research Symposium at Raleigh, NC on March 25, 2015

Source: NC State University Libraries
Added: April 3, 2022

2015 speech

Enhancing fatty acid oxidation in newborn pigs to improve survivability

Lin, X., & Odle, J. (2015, July). Presented at the USDA-NIFA Project director’s meeting, JAM, Orlando, FL.

By: X. Lin & J. Odle

Event: USDA-NIFA Project director’s meeting at JAM, Orlando, FL on July 12, 2015

Source: NC State University Libraries
Added: April 3, 2022

2015 journal article

Essential nature of fatty acids for the modern lactating sow

Journal of Animal Science, 93(Suppl 2), 66.

By: D. Rosero, J. Odle, R. Boyd & E. van Heugten

Source: NC State University Libraries
Added: April 3, 2022

2015 speech

Food animal faculty retreat introduction

Odle, J. (2015, November). Presented at the Raleigh, NC.

By: J. Odle

Event: at Raleigh, NC on November 20, 2015

Source: NC State University Libraries
Added: April 3, 2022

2015 speech

Global food animal academy planning

Odle, J. (2015, November). Presented at the Dean Linton’s Open Fields, Raleigh, NC.

By: J. Odle

Event: Dean Linton’s Open Fields at Raleigh, NC on November 4, 2015

Source: NC State University Libraries
Added: April 3, 2022

2015 journal article

Global impact of improving feed efficiency and technology transfer efficacy

Journal of Animal Science, 93(Suppl 3), 599.

By: R. White, T. Applegate, G. Cromwell, D. Beitz, M. Galyean, M. Hall, P. Miller, J. Odle, W. Weiss, M. Hanigan

Source: NC State University Libraries
Added: April 3, 2022

2015 article

Impact of dietary lipids on sow milk composition and balance of essential fatty acids during lactation in prolific sows

Rosero, D. S., Odle, J., Mendoza, S. M., Boyd, R. D., Fellner, V., & Heugten, E. (2015, June). JOURNAL OF ANIMAL SCIENCE, Vol. 93, pp. 2935–2947.

By: D. Rosero n, J. Odle n, S. Mendoza n, R. Boyd n, V. Fellner n & E. Heugten n

Contributors: D. Rosero n, J. Odle n, S. Mendoza n, R. Boyd n, V. Fellner n & E. Heugten n

author keywords: essential fatty acids; lactation; lipids; milk; sow
MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Diet / veterinary; Dietary Fats / pharmacology; Dietary Supplements; Fatty Acids / metabolism; Female; Lactation / physiology; Linoleic Acid; Milk / chemistry; Pregnancy; Reproduction / drug effects; Soybeans; Swine / physiology; Zea mays
TL;DR: In conclusion, lipid supplementation to sow lactation diets improved milk fat secretion and created a positive balance during lactation, which may prove to be beneficial for the development of nursing piglets and the subsequent reproduction of sows. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Impact of dietary lipids on sow milk composition and balance of essential fatty acids during lactation in prolific sows

Journal of Animal Science, 93(6), 2935–2947.

By: D. Rosero, J. Odle, S. Mendoza, R. Boyd, V. Fellner & E. Heugten

Contributors: D. Rosero, J. Odle, S. Mendoza, R. Boyd, V. Fellner & E. Heugten

Source: ORCID
Added: November 19, 2019

2015 speech

Managing dietary fat to produce healthy pigs, healthy pork and healthy people

Odle, J. (2015, May). Presented at the North Carolina Swine Day, Clinton, NC.

By: J. Odle

Event: North Carolina Swine Day at Clinton, NC on May 12, 2015

Source: NC State University Libraries
Added: April 3, 2022

2015 journal article

Maternal Undernutrition Affects Expression of Genes Associated with Ileal Development and Metabolism in Full‐term Offspring

The FASEB Journal, 29(S1).

By: C. Man n, Y. Fan n, H. Lima n, S. Jacobi n, S. Lui n, J. Odle n, L. Xi n

TL;DR: The results strongly suggest that nutrient restriction during pregnancy can affect the programming of fetal ileum development and metabolism via regulation of gene expression and that post‐transcriptional mechanisms might be involved in. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 20, 2022

2015 journal article

Milk Oligosaccharides Modulate Colonic Microbiota of Formula‐Fed Piglets

The FASEB Journal, 29(S1).

By: S. Jacobi n, T. Yatsunenko*, B. Berg*, M. Chichlowski* & J. Odle n

UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 26, 2022

2015 report

NANP-NRSP9 Coordinating Committee Update

By: G. Cromwell, T. Applegate, D. Beitz, M. Galyean, M. Hall, M. Hanigan, J. Odle, W. Weiss, C. Baer

Source: NC State University Libraries
Added: April 3, 2022

2015 speech

Neonatal pig nutritional biochemistry

Odle, J. (2015, June). Presented at the Novozymes North America, Inc, Franklinton, NC.

By: J. Odle

Event: Novozymes North America, Inc at Franklinton, NC on June 19, 2015

Source: NC State University Libraries
Added: April 3, 2022

2015 speech

New dimensions of lipid metabolism in swine: epigenetic and intestinal effects of long-chain polyunsaturated fatty acids

Odle, J., Jacobi, S. K., & Lin, X. (2015, March). Presented at the NCCC-210 regional meeting, Boston, MA.

By: J. Odle, S. Jacobi & X. Lin

Event: NCCC-210 regional meeting at Boston, MA on March 27, 2015

Source: NC State University Libraries
Added: April 3, 2022

2015 review

Nutritional Impact of Dietary Plasma Proteins in Animals Undergoing Experimental Challenge and Implications for Patients with Inflammatory Bowel Disorders: A Meta-analysis

[Review of ]. ADVANCES IN NUTRITION, 6(5), 541–551.

By: R. Kuchibhatla, B. Petschow, J. Odle n & E. Weaver

author keywords: enteropathy; inflammatory bowel disease; IBS; agrimedical; plasma protein; immunoglobulin; barrier function; linear growth
MeSH headings : Animal Feed / analysis; Animals; Blood Proteins / administration & dosage; Databases, Factual; Dietary Proteins / administration & dosage; Disease Models, Animal; Humans; Inflammatory Bowel Diseases / drug therapy; Randomized Controlled Trials as Topic
TL;DR: This meta-analysis evaluated the ability of PPIs to promote weight gain and food intake in weanling animals after oral challenge with various enteric pathogens or bacterial toxins and found the proinflammatory cytokines interleukin (IL) 1β, IL-6, and tumor necrosis factor α were significantly lower in animals fed dietary PPIs. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 speech

Nutritional biochemistry of bioactive fatty acids in the neonatal pig

Odle, J. (2015, April). Presented at the Department of Molecular and Structural Biochemistry, North Carolina State University, Raleigh, NC.

By: J. Odle

Event: Department of Molecular and Structural Biochemistry, North Carolina State University at Raleigh, NC on April 9, 2015

Source: NC State University Libraries
Added: April 3, 2022

2015 speech

Nutritional biochemistry of bioactive fatty acids in young pigs

Odle, J. (2015, April). Presented at the International Lipid Symposium, Ames, IA.

By: J. Odle

Event: International Lipid Symposium at Ames, IA on April 21, 2015

Source: NC State University Libraries
Added: April 3, 2022

2015 speech

Nutritional biochemistry supporting neonatal gastrointestinal health

Odle, J. (2015, May). Presented at the BioResource International, Raleigh, NC.

By: J. Odle

Event: BioResource International at Raleigh, NC on May 21, 2015

Source: NC State University Libraries
Added: April 3, 2022

2015 speech

Nutritional determinates of neonatal growth, development & health

Odle, J. (2015, June). Nutritional determinates of neonatal growth, development & health. Presented at the CALS/CVM exchange with PPK Animal Health.

By: J. Odle

Event: CALS/CVM exchange with PPK Animal Health on June 29, 2015

Source: NC State University Libraries
Added: April 3, 2022

2015 journal article

Nutritional impact of dietary plasma proteins in animals undergoing experimental challenge and implications for patients with inflammatory bowel disorders: A meta-analysis

Advances in Nutrition, 6(5), 541–551. http://www.scopus.com/inward/record.url?eid=2-s2.0-84953398079&partnerID=MN8TOARS

By: R. Kuchibhatla, B. Petschow, J. Odle & E. Weaver

Contributors: R. Kuchibhatla, B. Petschow, J. Odle & E. Weaver

Source: ORCID
Added: November 19, 2019

2015 journal article

Peptidoglycan Recognition Proteins Are Differentially Regulated by Time and Long‐Chain Polyunsaturated Fatty Acids In Neonatal Pig Intestinal Epithelial Cells, IPECJ2

The FASEB Journal, 29(S1).

By: L. Nieforth n, J. Odle n & S. Jacobi n

TL;DR: Data implicate a potential mechanism for dietary LC‐PUFA to modulate intestinal health by altering mucosal signaling mechanisms between luminal microbiotia, enterocytes and the mucosal immune system. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 26, 2022

2015 journal article

Peroxidised dietary lipids impair intestinal function and morphology of the small intestine villi of nursery pigs in a dose-dependent manner

BRITISH JOURNAL OF NUTRITION, 114(12), 1985–1992.

Contributors: D. Rosero n, J. Odle n, A. Moeser*, R. Boyd n & E. Van Heugten n

author keywords: Lipid peroxidation; Oxidative stress; Pigs; Small intestine
MeSH headings : Animals; Dietary Fats / administration & dosage; Dietary Fats / pharmacology; Digestion; Dose-Response Relationship, Drug; Feeding Behavior; Female; Intestinal Absorption; Intestinal Mucosa / metabolism; Intestine, Small / drug effects; Intestine, Small / physiology; Male; Mannitol / administration & dosage; Mannitol / metabolism; Peroxides / chemistry; Soybean Oil / metabolism; Swine / growth & development; Xylose / administration & dosage
TL;DR: Investigating the effect of increasing degrees of lipid peroxidation on structure and function of the small intestine of nursery pigs found that it progressively diminished animal performance and modified the function and morphology of theSmall intestine of Nursery pigs. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Supplementation of Maternal Diets with Choline, B‐vitamin and Docosahexaenoic Acid (DHA) Alters Gene Expressions Associated with Hepatic Lipid Metabolism in Offspring

The FASEB Journal, 29(S1).

By: L. Xi n, C. Man n, H. Lima n, S. Jacobi n, S. Lui n & J. Odle n

UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 20, 2022

2015 speech

Swine nutritional models: The importance of neonatal nutrition

Odle, J. (2015, June). Presented at the HuVe Pharma, Inc. Russian delegation, Raleigh, NC.

By: J. Odle

Event: HuVe Pharma, Inc. Russian delegation at Raleigh, NC on June 24, 2015

Source: NC State University Libraries
Added: April 3, 2022

2015 speech

Team science manages dietary fat to yield healthy pigs, healthy pork and healthy people

Odle, J. (2015, March). Presented at the NCSU College of Agriculture and Life Sciences AG Day, Raleigh, NC.

By: J. Odle

Event: NCSU College of Agriculture and Life Sciences AG Day at Raleigh, NC on March 17, 2015

Source: NC State University Libraries
Added: April 3, 2022

2015 journal article

Transplacental induction of fatty acid oxidation in term fetal pigs by the peroxisome proliferator-activated receptor alpha agonist clofibrate

Journal of Animal Science and Biotechnology, 6(1).

By: X. Lin n, S. Jacobi n & J. Odle n

Contributors: X. Lin n, S. Jacobi n & J. Odle n

author keywords: Clofibrate; Fatty acid oxidation; Pigs; Placenta transfer
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2014 speech

Agrimedical research to meet the grand challenge of improving global human health

Odle, J. (2014, March). Presented at the Junior Statesmen in Biosciences Program, Raleigh, NC.

By: J. Odle

Event: Junior Statesmen in Biosciences Program at Raleigh, NC on March 27, 2014

Source: NC State University Libraries
Added: April 3, 2022

2014 speech

Applications of novel bioactive lipids in developmental nutrition of the neonate

Odle, J. (2014, April). Presented at the NCCC-210 Regional meeting, San Diego, CA.

By: J. Odle

Event: NCCC-210 Regional meeting at San Diego, CA on April 25, 2014

Source: NC State University Libraries
Added: April 3, 2022

2014 conference paper

Blood Biomarkers for Growth Performance in Gilts Infected with Porcine Reproductive and Respiratory Syndrome (PRRS) virus

Serão, N. V. L., Burkey, T. E., Gourley, G., Weber, T. E., Fitzsimmons, M., Schwartz, K., … Gabler, N. K. (2014, December 5). Presented at the North American PRRS Symposium, Chicago, IL.

By: N. Serão, T. Burkey, G. Gourley, T. Weber, M. Fitzsimmons, K. Schwartz, C. Sparks, J. Odle, J. Dekkers, N. Gabler

Event: North American PRRS Symposium at Chicago, IL on December 5, 2014

Source: NC State University Libraries
Added: April 3, 2022

2014 speech

CALS-CVM collaboration on Food-Animal Initiative

Odle, J. (2014, November). Presented at the Agriculture Foundation, University Club, Raleigh, NC.

By: J. Odle

Event: Agriculture Foundation at University Club, Raleigh, NC on November 6, 2014

Source: NC State University Libraries
Added: April 3, 2022

2014 speech

CVM-CALS collaboration to create an Academy for Global Food-Animal Biosciences

Odle, J. (2014, September). Presented at the Food Animal Stakeholders meeting, PNC Arena, Raleigh, NC.

By: J. Odle

Event: Food Animal Stakeholders meeting at PNC Arena, Raleigh, NC on September 27, 2014

Source: NC State University Libraries
Added: April 3, 2022

2014 speech

CVM-CALS collaboration to create an Academy for Global Food-Animal Biosciences

Odle, J. (2014, December). Presented at the Food Animal Stakeholders meeting. Lonnie Poole’s Players Retreat, NCSU Centennial Campus, Raleigh, NC.

By: J. Odle

Event: Food Animal Stakeholders meeting. Lonnie Poole’s Players Retreat at NCSU Centennial Campus, Raleigh, NC on December 4, 2014

Source: NC State University Libraries
Added: April 3, 2022

2014 article

Carnitine

Odle, J., Adams, S. H., & Vockley, J. (2014, May). ADVANCES IN NUTRITION, Vol. 5, pp. 289–290.

By: J. Odle n, S. Adams* & J. Vockley*

Contributors: J. Odle n, S. Adams* & J. Vockley*

MeSH headings : Carnitine / administration & dosage; Carnitine / deficiency; Humans; Mutation; Organic Cation Transport Proteins / genetics; Organic Cation Transport Proteins / metabolism; Recommended Dietary Allowances; Solute Carrier Family 22 Member 5
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2014 journal article

Characterization of PRRS progression in growing gilts using metabolic, cytokine, and complete blood count data

Journal of Animal Science, 92(E-Suppl. 2), 72.

By: N. Serão, T. Burkey, G. Gourley, T. Weber, M. FitzSimmons, K. Schwartz, C. Sparks, J. Odle, N. Gabler, J. Dekkers

Event: Midwest Regional Animal Science Meetings at Des Moines, IA

Source: NC State University Libraries
Added: April 3, 2022

2014 journal article

Clofibrate Increases Long-Chain Fatty Acid Oxidation by Neonatal Pigs

The Journal of Nutrition, 144(11), 1688–1693.

By: X. Bai n, X. Lin n, J. Drayton n, Y. Liu n, C. Ji* & J. Odle n

Contributors: X. Bai n, X. Lin n, J. Drayton n, Y. Liu n, C. Ji* & J. Odle n

MeSH headings : Animals; Animals, Newborn; Anticholesteremic Agents / pharmacology; Clofibrate / pharmacology; Fatty Acids / metabolism; Liver / drug effects; Liver / metabolism; Male; Oxidation-Reduction / drug effects; RNA, Messenger / genetics; RNA, Messenger / metabolism; Weight Gain
TL;DR: Clofibrate may improve in vivo LCFA oxidative utilization in neonatal pigs to increase efficiency of milk fat utilization by newborn pigs. (via Semantic Scholar)
Sources: ORCID, Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2014 speech

Comparative lipid metabolism in a piglet model of pediatric nutrition and intestinal health

Odle, J. (2014, March). Presented at the Arkansas Children’s Nutrition Center, Arkansas Children’s Hospital, USDA-ARS, Little Rock, AR.

By: J. Odle

Event: Arkansas Children’s Nutrition Center, Arkansas Children’s Hospital, USDA-ARS at Little Rock, AR on March 6, 2014

Source: NC State University Libraries
Added: April 3, 2022

2014 speech

Creation of an Academy for Global Food-Animal Biosciences

Odle, J. (2014, October). Presented at the CALS Advancement Office, Brickhaven, Raleigh, NC.

By: J. Odle

Event: CALS Advancement Office at Brickhaven, Raleigh, NC on October 1, 2014

Source: NC State University Libraries
Added: April 3, 2022

2014 speech

Creation of an Academy for Global Food-Animal Biosciences

Odle, J. (2014, December). Presented at the Elanco Animal Health.

By: J. Odle

Event: Elanco Animal Health on December 2, 2014

Source: NC State University Libraries
Added: April 3, 2022

2014 speech

Designing a global animal nutrition network

Odle, J. (2014, June). Presented at the National Animal Nutrition Program Meeting, Washington, DC.

By: J. Odle

Event: National Animal Nutrition Program Meeting at Washington, DC on June 20, 2014

Source: NC State University Libraries
Added: April 3, 2022

2014 journal article

Dietary Isomers of Sialyllactose Increase Ganglioside Sialic Acid Concentrations in the Corpus Callosum and Cerebellum of Formula‐fed Piglets (LB320)

The FASEB Journal, 28(S1).

By: S. Jacobi n, D. Li*, S. Dasgupta*, R. Yu*, B. Berg*, M. Chichlowski*, J. Odle n

TL;DR: In conclusion, supplementation of formula with 3’‐ or 6'‐SL can enrich ganglioside SA in the brain of suckling piglets. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: March 5, 2022

2014 journal article

Dietary supplementation of aspartate enhances intestinal integrity and energy status in weanling piglets after lipopolysaccharide challenge

The Journal of Nutritional Biochemistry, 25(4), 456–462.

By: D. Pi*, Y. Liu*, H. Shi*, S. Li*, J. Odle n, X. Lin n, H. Zhu*, F. Chen* ...

Contributors: D. Pi*, Y. Liu*, H. Shi*, S. Li*, J. Odle n, X. Lin n, H. Zhu*, F. Chen*, Y. Hou*, W. Leng*

author keywords: Aspartate; Intestine; Energy status; Weanling piglets; Lipopolysaccharide
MeSH headings : AMP-Activated Protein Kinases / genetics; AMP-Activated Protein Kinases / metabolism; Adenosine Diphosphate / metabolism; Adenosine Monophosphate / metabolism; Adenosine Triphosphate / metabolism; Animals; Aspartic Acid / pharmacology; Body Weight / drug effects; DNA / metabolism; Dietary Supplements; Histone Deacetylases / genetics; Intestinal Mucosa / drug effects; Intestinal Mucosa / metabolism; Intestines / drug effects; Lactase / metabolism; Lipopolysaccharides / toxicity; Phosphorylation / drug effects; Proteins / metabolism; Sucrase / metabolism; Swine; Transcription Factors / genetics; Weaning
TL;DR: Results indicate that Asp may alleviate LPS-induced intestinal damage and improve intestinal energy status. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Differential expression of heat shock transcription factors and heat shock proteins after acute and chronic heat stress in laying chickens (Gallus gallus)

PLoS One, 9(7), e102204.

By: J. Xie*, L. Tang*, L. Lu*, L. Zhang*, L. Xi n, H. Liu n, J. Odle n, X. Luo*

Contributors: J. Xie*, L. Tang*, L. Lu*, L. Zhang*, L. Xi n, H. Liu n, J. Odle n, X. Luo*

Ed(s): S. Cotterill

MeSH headings : Animals; Behavior, Animal; Chickens / genetics; Chickens / metabolism; DNA-Binding Proteins / genetics; Female; Gene Expression Regulation; HSP70 Heat-Shock Proteins / genetics; HSP90 Heat-Shock Proteins / genetics; Heat Shock Transcription Factors; Heat-Shock Proteins / genetics; Heat-Shock Response / genetics; Male; Malondialdehyde / metabolism; RNA, Messenger; Superoxide Dismutase / metabolism; Temperature; Time Factors; Transcription Factors / genetics
TL;DR: The differential expressions of HSF and HSP genes in different tissues of laying broiler breeder chickens suggested that anti-heat stress mechanisms might be provoked more profoundly in the heart, by which the muscle was least protected during heat stress. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2014 conference paper

Effects of choline, B-vitamins and docosahexaenoic acid (DHA) supplementation on biological, molecular, and genomic characteristics of intra-uterine growth retardation (IUGR) in a feed-restricted swine model

Presented at the Swine in Biomedical Research Conference, Raleigh, NC.

By: H. Lima, S. Jacobi, C. Man, K. Walker, J. Sommer, W. Flowers, A. Blikslager, L. Gonzales ...

Event: Swine in Biomedical Research Conference at Raleigh, NC on July 6, 2014

Source: NC State University Libraries
Added: April 3, 2022

2014 speech

Effects of chronic malnutrition on growth and microbial succession in commercial swine

Odle, J. (2014, April). Presented at the Matatu Scientific Advisory Meeting, St. Louis, MO.

By: J. Odle

Event: Matatu Scientific Advisory Meeting at St. Louis, MO on April 1, 2014

Source: NC State University Libraries
Added: April 3, 2022

2014 journal article

Effects of methylating vitamins and docosahexaenoic acid supplementation on intra‐uterine growth retardation in a feed‐restricted swine model (1033.8)

The FASEB Journal, 28(S1).

By: H. Lima n, S. Jacobi n, C. Man n, K. Walker n, J. Sommer n, W. Flowers n, A. Blikslager n, L. Xi n, J. Odle n

UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 20, 2022

2014 conference paper

Maternal supplementation of choline, B-vitamins and docosahexaenoic acid (DHA) during global nutrient restriction alter abundance of miRNA and mRNA associated with hepatic lipid metabolism in term fetal piglets

Presented at the Swine in Biomedical Research Conference, Raleigh, NC.

By: C. Man, L. Xi, H. Lima, S. Jacobi, C. Resnyk, S. Liu, J. Odle

Event: Swine in Biomedical Research Conference at Raleigh, NC on July 6, 2014

Source: NC State University Libraries
Added: April 3, 2022

2014 journal article

Methylated Medium‐ and Long‐Chain Fatty Acids Provide Novel Sources of Anaplerotic Carbon for Fasting or Exercising Mice (LB438)

The FASEB Journal, 28(S1).

By: J. Drayton n, X. Lin n, S. Jacobi n, R. Shanely*, M. McIntosh* & J. Odle n

TL;DR: Results were consistent with the hypothesis that methyl‐branched fatty acids may provide anaplerotic carbon and thereby stimulate in vitro fatty acid oxidation and are consistent with previous studies of methylated fatty acids using TCA cycle intermediates. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 20, 2022

2014 speech

Nutritional factors influencing intestinal health of the neonate: Insights drawn from a piglet model

Odle, J. (2014, October). Presented at the Lesaffre Animal Health & Productivity Forum, Monterrey, CA.

By: J. Odle

Event: Lesaffre Animal Health & Productivity Forum at Monterrey, CA on October 17, 2014

Source: NC State University Libraries
Added: April 3, 2022

2014 speech

Nutritional keys to unlocking the growth potential of the newly weaned pig

Odle, J. (2014, October). Presented at the Techmix, Inc. and Kansas State University Applied Swine Nutrition Meeting, Manhattan, KS.

By: J. Odle

Event: Techmix, Inc. and Kansas State University Applied Swine Nutrition Meeting at Manhattan, KS on October 14, 2014

Source: NC State University Libraries
Added: April 3, 2022

2014 speech

Nutritional support of pigs afflicted with viral enteritis

Odle, J. (2014, February). Presented at the Techmix, Inc. and Swine Vet Center, St. Peter, MN.

By: J. Odle

Event: Techmix, Inc. and Swine Vet Center at St. Peter, MN on February 20, 2014

Source: NC State University Libraries
Added: April 3, 2022

2014 speech

Peptidoglycan recognition proteins 2 and 4 are differentially regulated over time and acutely regulated by long-chain polyunsaturated fatty acid treatment in the neonatal pig intestinal epithelial cell line, IPECJ2

Presented at the Undergraduate Research Symposium, Raleigh, NC.

By: L. Nieforth, S. Jacobi & J. Odle

Event: Undergraduate Research Symposium at Raleigh, NC

Source: NC State University Libraries
Added: April 3, 2022

2014 conference paper

Prebiotics containing sialic acid increase ganglioside sialic acid concentrations in the corpus callosum and cerebellum of formula-fed piglets

Jacobi, S. K., Li, D., Dasgupta, S., Yu, R. K., Berg, B. M., Chichlowski, M., & Odle, J. (2014, July 6). Presented at the Swine in Biomedical Research Conference, Raleigh, NC.

By: S. Jacobi, D. Li, S. Dasgupta, R. Yu, B. Berg, M. Chichlowski, J. Odle

Event: Swine in Biomedical Research Conference at Raleigh, NC on July 6, 2014

Source: NC State University Libraries
Added: April 3, 2022

2014 journal article

Response of sow and progeny to supplementation of dietary essential fatty acids during lactation

Journal of Animal Science, 92(E-Suppl. 2), 64.

By: D. Rosero, E. van Heugten, J. Odle, M. McCulley & R. Boyd

Event: Midwest Regional Animal Science Meetings at Des Moines, IA

Source: NC State University Libraries
Added: April 3, 2022

2014 speech

Swine nutritional models: The importance of neonatal nutrition

Odle, J. (2014, July). Presented at the Swine in Biomedical Research Conference, Raleigh, NC.

By: J. Odle

Event: Swine in Biomedical Research Conference at Raleigh, NC on July 7, 2014

Source: NC State University Libraries
Added: April 3, 2022

2014 conference paper

The National Animal Nutrition Program

Cromwell, G., Beitz, D., Galyean, M., Applegate, T., Hanigan, M., Weiss, B., … Baer, C. K. (2014, August 1). Presented at the Comparative Nutrition Society Annual Meeting, Flat Rock, NC.

By: G. Cromwell, D. Beitz, M. Galyean, T. Applegate, M. Hanigan, B. Weiss, J. Odle, M. Hall, P. Miller, C. Baer

Event: Comparative Nutrition Society Annual Meeting at Flat Rock, NC on August 1, 2014

Source: NC State University Libraries
Added: April 3, 2022

2014 speech

The neonatal pig as an agrimedical model for neonatal nutrition and metabolism

Odle, J. (2014, March). Presented at the Junior Bio Statesman Program, Raleigh, NC.

By: J. Odle

Event: Junior Bio Statesman Program at Raleigh, NC on March 27, 2014

Source: NC State University Libraries
Added: April 3, 2022

2014 speech

University Global Partnership Network (UGPN). One Health Collaboration: One Nutrition

Odle, J. (2014, February). Presented at the University of Surrey, Guildford, UK.

By: J. Odle

Event: University of Surrey at Guildford, UK on February 27, 2014

Source: NC State University Libraries
Added: April 3, 2022

2013 conference paper

A porcine model studying prophylaxis and treatment of neonatal enteric disease with long-chain polyunsaturated fatty acids

Jacobi, S. K., Moeser, A. J., Xi, L., Blikslager, A. T., & Odle, J. (2013, September 22). Presented at the Innovate 2013 Conference, American Society of Animal Science, Braselton, GA.

By: S. Jacobi, A. Moeser, L. Xi, A. Blikslager & J. Odle

Event: Innovate 2013 Conference, American Society of Animal Science at Braselton, GA on September 22, 2013

Source: NC State University Libraries
Added: April 3, 2022

2013 journal article

Acute effects of rotavirus and malnutrition on intestinal barrier function in neonatal piglets

World Journal of Gastroenterology, 19(31), 5094–5102.

By: S. Jacobi n, A. Moeser, A. Blikslager, J. Rhoads, B. Corl, R. Harrell, J. Odle

Contributors: S. Jacobi n, A. Moeser, A. Blikslager, J. Rhoads, B. Corl, R. Harrell, J. Odle

author keywords: Rotavirus gastroenteritis; Kwashiorkor; Occludin; Ussing chamber; Villus
MeSH headings : Animals; Animals, Newborn; Diarrhea / metabolism; Diarrhea / virology; Disease Models, Animal; Electric Impedance; Humans; Infant Formula / metabolism; Infant, Newborn; Intestinal Absorption; Intestinal Mucosa / metabolism; Intestinal Mucosa / pathology; Intestinal Mucosa / virology; Mannitol / metabolism; Occludin / metabolism; Permeability; Protein-Energy Malnutrition / metabolism; Protein-Energy Malnutrition / pathology; Protein-Energy Malnutrition / virology; Rotavirus Infections / metabolism; Rotavirus Infections / pathology; Rotavirus Infections / virology; Swine; Tight Junctions / metabolism; Tight Junctions / virology; Time Factors; Weight Loss
TL;DR: Overall, malnutrition had no additive effects to rotavirus infection on intestinal barrier function at day 3 post-infection in a neonatal piglet model. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

Comparative metabolic physiology in the 'omics' Era: A call to arms, paws, flippers, and claws

Advances in Nutrition, 4(5), 568–569.

By: S. Adams*, K. Barnes* & J. Odle n

Contributors: S. Adams*, K. Barnes* & J. Odle n

MeSH headings : Animals; Congresses as Topic; Humans; Metabolomics / methods; Metabolomics / trends; Nutritional Sciences / methods; Nutritional Sciences / trends; Physiology, Comparative / methods; Physiology, Comparative / trends; Societies, Scientific; Translational Research, Biomedical / methods; Translational Research, Biomedical / trends; United States
TL;DR: Comparative metabolic physiology provides a context by which new "omics" technologies and other approaches can be coupled to multi-species metabolic phenotype diversity. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
15. Life on Land (Web of Science)
Sources: NC State University Libraries, ORCID, NC State University Libraries
Added: August 6, 2018

2013 journal article

Detrimental effects of oxidized lipids in nursery diets

Journal of Animal Science, 90(E-Suppl. 1), 12.

By: D. Rosero, J. Odle, A. Moeser, R. Boyd & E. van Heugten

Event: Midwest Regional Animal Science Meetings at Des Moines, IA

Source: NC State University Libraries
Added: April 3, 2022

2013 journal article

Dietary supplementation of Bifidobacterium longum strain AH1206 increases its cecal abundance and elevates intestinal interleukin-10 expression in the neonatal piglet

Food and Chemical Toxicology, 60, 116–122.

By: T. Herfel n, S. Jacobi n, X. Lin n, Z. Jouni*, M. Chichlowski*, C. Stahl n, J. Odle n

Contributors: T. Herfel n, S. Jacobi n, X. Lin n, Z. Jouni*, M. Chichlowski*, C. Stahl n, J. Odle n

author keywords: Bifidobacteria; Probiotic; Infant; Intestinal health; Immune system; IL-10
MeSH headings : Animal Feed / microbiology; Animals; Animals, Newborn; Bifidobacterium; Cecum / microbiology; Colony Count, Microbial; Dietary Supplements; Immunoglobulin G / blood; Immunoglobulin M / blood; Interleukin-10 / genetics; Interleukin-10 / metabolism; Probiotics / administration & dosage; Swine; Weight Gain
TL;DR: Dietary supplementation with B. longum (AH1206) may be safe for human infants based on a lack of growth, development or deleterious immune-related effects observed in piglets, based on findings in the suckling piglet model. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

Effects of creep feeding and supplemental glutamine or glutamine plus glutamate (Aminogut) on pre- and post-weaning growth performance and intestinal health of piglets

JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY, 4(1).

By: R. Cabrera n, J. Usry*, C. Arrellano n, E. Nogueira, M. Kutschenko, A. Moeser n, J. Odle n

Contributors: R. Cabrera n, J. Usry*, C. Arrellano n, E. Nogueira, M. Kutschenko, A. Moeser n, J. Odle n

author keywords: Creep feeding; Glutamine; Growth performance; Intestinal health; SEM; Villi
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2013 speech

Establishing a transdisciplinary graduate program in functional foods, bioactive food components, and human health

Odle, J. (2013, April). Presented at the USDA project director meeting, Experimental Biology, Boston, MA.

By: J. Odle

Event: USDA project director meeting, Experimental Biology at Boston, MA on April 20, 2013

Source: NC State University Libraries
Added: April 3, 2022

2013 journal article

Fish Oil Alleviates Activation of the Hypothalamic-Pituitary-Adrenal Axis Associated with Inhibition of TLR4 and NOD Signaling Pathways in Weaned Piglets after a Lipopolysaccharide Challenge

The Journal of Nutrition, 143(11), 1799–1807.

By: Y. Liu*, F. Chen*, Q. Li*, J. Odle n, X. Lin n, H. Zhu*, D. Pi*, Y. Hou* ...

Contributors: Y. Liu*, F. Chen*, Q. Li*, J. Odle n, X. Lin n, H. Zhu*, D. Pi*, Y. Hou*, Y. Hong*, H. Shi*

MeSH headings : Adrenal Glands / drug effects; Adrenal Glands / metabolism; Adrenocorticotropic Hormone / blood; Animals; Corticotropin-Releasing Hormone / blood; Cyclooxygenase 2 / genetics; Cyclooxygenase 2 / metabolism; Disease Models, Animal; Docosahexaenoic Acids / pharmacology; Down-Regulation; Eicosapentaenoic Acid / pharmacology; Fish Oils / pharmacology; Hypothalamo-Hypophyseal System / drug effects; Hypothalamo-Hypophyseal System / metabolism; Hypothalamus / drug effects; Hypothalamus / metabolism; Interleukin-1 Receptor-Associated Kinases / genetics; Interleukin-1 Receptor-Associated Kinases / metabolism; Lipopolysaccharides / toxicity; Myeloid Differentiation Factor 88 / genetics; Myeloid Differentiation Factor 88 / metabolism; Nod Signaling Adaptor Proteins / antagonists & inhibitors; Nod Signaling Adaptor Proteins / genetics; Nod Signaling Adaptor Proteins / metabolism; Pituitary Gland / drug effects; Pituitary Gland / metabolism; Pituitary-Adrenal System / drug effects; Pituitary-Adrenal System / metabolism; Pro-Opiomelanocortin / blood; RNA, Messenger / genetics; RNA, Messenger / metabolism; Spleen / drug effects; Spleen / metabolism; Swine; Thymus Gland / drug effects; Thymus Gland / metabolism; Toll-Like Receptor 4 / antagonists & inhibitors; Toll-Like Receptor 4 / genetics; Toll-Like Receptor 4 / metabolism; Tumor Necrosis Factor-alpha / genetics; Tumor Necrosis Factor-alpha / metabolism; Weaning
TL;DR: Dietary treatment with fish oil could mitigate LPS-induced activation of the hypothalamic-pituitary-adrenal (HPA) axis through inhibition of Toll-like receptor 4 and nucleotide-binding oligomerization domain protein signaling pathways, and the beneficial effects of FO on the HPA axis may be associated with decreasing the production of brain or peripheral proinflammatory cytokines through inhibition. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

Fish Oil Increases Muscle Protein Mass and Modulates Akt/FOXO, TLR4, and NOD Signaling in Weanling Piglets After Lipopolysaccharide Challenge

The Journal of Nutrition, 143(8), 1331–1339.

MeSH headings : Animals; Cyclooxygenase 2 / genetics; Cyclooxygenase 2 / metabolism; Docosahexaenoic Acids / administration & dosage; Eicosapentaenoic Acid / administration & dosage; Fish Oils / administration & dosage; Forkhead Transcription Factors / genetics; Forkhead Transcription Factors / metabolism; Lipopolysaccharides / adverse effects; Muscle Proteins / metabolism; Muscle, Skeletal / drug effects; Muscle, Skeletal / metabolism; Myeloid Differentiation Factor 88 / genetics; Myeloid Differentiation Factor 88 / metabolism; NF-kappa B / genetics; NF-kappa B / metabolism; Nod1 Signaling Adaptor Protein / genetics; Nod1 Signaling Adaptor Protein / metabolism; Proto-Oncogene Proteins c-akt / genetics; Proto-Oncogene Proteins c-akt / metabolism; Signal Transduction / drug effects; Swine; Toll-Like Receptor 4 / genetics; Toll-Like Receptor 4 / metabolism; Tumor Necrosis Factor-alpha / genetics; Tumor Necrosis Factor-alpha / metabolism
TL;DR: Results indicate fish oil may suppress muscle proinflammatory cytokine production via regulation of TLR and NOD signaling pathways and therefore improve muscle protein mass, possibly through maintenance of Akt/FOXO signaling. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2013 conference paper

Introduction to "And they ate happily ever after: Lifespan nutrition for health and vitality"

Odle, J. (2013, July 26). Presented at the Webinar and Conference, Kannapolis, NC.

By: J. Odle

Event: Webinar and Conference at Kannapolis, NC on July 26, 2013

Source: NC State University Libraries
Added: April 3, 2022

2013 speech

Introduction to Adipose symposium

Adams, S. H., Barnes, K., & Odle, J. (2013, April). Presented at the Experimental Biology Meetings, Boston, MA.

By: S. Adams, K. Barnes & J. Odle

Event: Experimental Biology Meetings at Boston, MA on April 19, 2013

Source: NC State University Libraries
Added: April 3, 2022

2013 speech

Liquid diets for early-weaned pigs: A “solution” for postweaning morbidity and mortality

Odle, J. (2013, December). Presented at the Nutreco, Boxmeer, The Netherlands.

By: J. Odle

Event: Nutreco at Boxmeer, The Netherlands on December 5, 2013

Source: NC State University Libraries
Added: April 3, 2022

2013 journal article

Lysine requirement of 1.5-5.5 kg pigs fed liquid diets

ANIMAL PRODUCTION SCIENCE, 54(5), 608–615.

By: J. Eisemann n, H. Lewis n, A. Broome n, K. Sullivan n, R. Boyd, J. Odle n, R. Harrell n

Contributors: J. Eisemann n, H. Lewis n, A. Broome n, K. Sullivan n, R. Boyd, J. Odle n, R. Harrell n

author keywords: neonatal pigs
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2013 journal article

Measures of immune function as biomarkers in serum of pigs infected with porcine reproductive and respiratory syndrome virus

Journal of Animal Science, 90(E-Suppl. 1), 48.

By: A. Rakhshandeh, T. Burkey, T. Weber, M. Fitzsimmons, K. Schwartz, J. Dekkers, C. Sparks, J. Odle, N. Gabler, G. Gourley

Event: Midwest Regional Animal Science Meetings at Des Moines, IA

Source: NC State University Libraries