Works (24)

Updated: July 9th, 2023 21:19

2019 review

MARCKS and Lung Disease

[Review of ]. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 60(1), 16–27.

By: M. Sheats*, Q. Yin n, S. Fang n, J. Park n, A. Crews n, I. Parikh*, B. Dickson*, K. Adler n

author keywords: MARCKS; lung disease; inflammation; cancer
MeSH headings : Animals; Humans; Lung Diseases / metabolism; Lung Diseases / physiopathology; Myristoylated Alanine-Rich C Kinase Substrate / metabolism
Sources: Web Of Science, ORCID
Added: January 14, 2019

2018 journal article

Bacterial and fungal communities, fermentation, and aerobic stability of conventional hybrids and brown midrib hybrids ensiled at low moisture with or without a homo- and heterofermentative inoculant

JOURNAL OF DAIRY SCIENCE, 101(4), 3057–3076.

By: J. Romero*, Y. Joo*, J. Park n, F. Tiezzi n, E. Gutierrez-Rodriguez n & M. Castillo n

author keywords: silage; inoculant; hybrid; next-generation sequencing
MeSH headings : Bacteria / classification; Fermentation; Fungi / classification; Microbiota / physiology; Nutritive Value; Random Allocation; Silage / analysis; Silage / microbiology; Zea mays / chemistry
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

An Inhaled Inhibitor of Myristoylated Alanine-Rich C Kinase Substrate Reverses LPS-Induced Acute Lung Injury in Mice

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 55(5), 617–622.

By: Q. Yin n, S. Fang n, J. Park*, A. Crews n, I. Parikh* & K. Adler n

author keywords: myristoylated alanine-rich C kinase substrate; acute lung injury; LPS; neutrophils
MeSH headings : Acute Lung Injury / chemically induced; Acute Lung Injury / drug therapy; Aerosols / administration & dosage; Aerosols / pharmacology; Animals; Behavior, Animal; Bronchoalveolar Lavage Fluid; Cytokines / metabolism; Female; Inflammation Mediators / metabolism; Intracellular Signaling Peptides and Proteins / antagonists & inhibitors; Intracellular Signaling Peptides and Proteins / metabolism; Leukocytes / metabolism; Lipopolysaccharides; Lung / drug effects; Lung / metabolism; Lung / pathology; Membrane Proteins / antagonists & inhibitors; Membrane Proteins / metabolism; Mice, Inbred BALB C; Myristoylated Alanine-Rich C Kinase Substrate; NF-kappa B / metabolism; Peptides / administration & dosage; Peptides / pharmacology; Peptides / therapeutic use
Source: Web Of Science
Added: August 6, 2018

2013 journal article

MARCKS and HSP70 interactions regulate mucin secretion by human airway epithelial cells in vitro

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 304(8), L511–L518.

By: S. Fang n, A. Crews n, W. Chen*, J. Park n, Q. Yin n, X. Ren*, K. Adler n

author keywords: airway; mucin; secretion; myristoylated alanine-rich C kinase substrate; heat shock protein 70
MeSH headings : Base Sequence; Bronchi / cytology; Bronchi / drug effects; Bronchi / metabolism; Bronchi / physiology; Cell Differentiation; Cells, Cultured; Epithelial Cells / cytology; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Epithelial Cells / physiology; HSP40 Heat-Shock Proteins / physiology; HSP70 Heat-Shock Proteins / antagonists & inhibitors; HSP70 Heat-Shock Proteins / genetics; HSP70 Heat-Shock Proteins / physiology; Humans; Intracellular Signaling Peptides and Proteins / genetics; Intracellular Signaling Peptides and Proteins / physiology; Membrane Proteins / genetics; Membrane Proteins / physiology; Microscopy, Confocal; Mucins / metabolism; Myristoylated Alanine-Rich C Kinase Substrate; Protein Transport; Pyrimidinones / pharmacology; RNA, Small Interfering / genetics; Recombinant Fusion Proteins / genetics; Recombinant Fusion Proteins / metabolism; Tetradecanoylphorbol Acetate / pharmacology
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Calpain and MARCKS protein regulation of airway mucin secretion

PULMONARY PHARMACOLOGY & THERAPEUTICS, 25(6), 427–431.

By: W. Lampe n, J. Park n, S. Fang n, A. Crews n & K. Adler n

author keywords: Airway; Mucin; MARCKS; Calpain; Secretion
MeSH headings : Bronchi / cytology; Bronchi / metabolism; Calpain / antagonists & inhibitors; Calpain / metabolism; Cell Line; Dose-Response Relationship, Drug; Epithelial Cells / metabolism; Fluorescence; Humans; Intracellular Signaling Peptides and Proteins / metabolism; Membrane Proteins / metabolism; Mucins / metabolism; Myristoylated Alanine-Rich C Kinase Substrate; Oligopeptides / administration & dosage; Oligopeptides / pharmacology; Protein Kinase C / metabolism; Tetradecanoylphorbol Acetate / pharmacology
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Directed migration of mouse macrophages in vitro involves myristoylated alanine-rich C-kinase substrate (MARCKS) protein

Journal of Leukocyte Biology, 92(3), 633–639.

By: T. Green n, J. Park n, Q. Yin n, S. Fang n, A. Crews n, S. Jones n, K. Adler n

author keywords: cytoplasmic translocation; J774A.1 cells; monocyte chemotactic protein 1; chemotaxis
MeSH headings : Actin Cytoskeleton / immunology; Actin Cytoskeleton / metabolism; Animals; Blotting, Western; Chemotaxis, Leukocyte / physiology; Intracellular Signaling Peptides and Proteins / immunology; Intracellular Signaling Peptides and Proteins / metabolism; Macrophages / immunology; Macrophages / metabolism; Membrane Proteins / immunology; Membrane Proteins / metabolism; Mice; Microscopy, Confocal; Myristoylated Alanine-Rich C Kinase Substrate; Protein Transport / physiology
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2011 journal article

A Common MUC5B Promoter Polymorphism and Pulmonary Fibrosis

NEW ENGLAND JOURNAL OF MEDICINE, 364(16), 1503–1512.

By: M. Seibold*, A. Wise*, M. Speer*, M. Steele*, K. Brown*, J. Loyd*, T. Fingerlin*, W. Zhang* ...

MeSH headings : Aged; Case-Control Studies; Chromosomes, Human, Pair 11; Female; Genetic Linkage; Genetic Predisposition to Disease; Genome-Wide Association Study; Humans; Idiopathic Pulmonary Fibrosis / genetics; Linkage Disequilibrium; Lung / metabolism; Lung Diseases, Interstitial / genetics; Male; Middle Aged; Mucin-5B / genetics; Mucin-5B / metabolism; Mutation; Polymorphism, Single Nucleotide; Promoter Regions, Genetic
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Mucin granule-associated proteins in human bronchial epithelial cells: the airway goblet cell "granulome"

RESPIRATORY RESEARCH, 12.

By: K. Raiford*, J. Park n, K. Lin*, S. Fang n, A. Crews n & K. Adler n

MeSH headings : Bronchi / chemistry; Bronchi / metabolism; Cells, Cultured; Cytoplasmic Granules / chemistry; Cytoplasmic Granules / metabolism; Cytoplasmic Granules / ultrastructure; Goblet Cells / chemistry; Goblet Cells / metabolism; Humans; Membrane Glycoproteins / chemistry; Membrane Glycoproteins / metabolism; Membrane Glycoproteins / ultrastructure; Mucins / chemistry; Mucins / metabolism; Respiratory Mucosa / chemistry; Respiratory Mucosa / metabolism
Source: Web Of Science
Added: August 6, 2018

2011 review

Regulation of mucin secretion and inflammation in asthma: A role for MARCKS protein?

[Review of ]. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1810(11), 1110–1113.

By: T. Green n, A. Crews n, J. Park n, S. Fang n & K. Adler n

author keywords: MARCKS; Mucin; Secretion; Asthma
MeSH headings : Animals; Asthma / etiology; Humans; Inflammation / etiology; Intracellular Signaling Peptides and Proteins / physiology; Membrane Proteins / physiology; Mucins / metabolism; Myristoylated Alanine-Rich C Kinase Substrate
Source: Web Of Science
Added: August 6, 2018

2010 journal article

MARCKS and Related Chaperones Bind to Unconventional Myosin V Isoforms in Airway Epithelial Cells

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 43(2), 131–136.

By: K. Lin n, S. Fang n, J. Park n, A. Crews n & K. Adler n

author keywords: airway; mucin; MARCKS; chaperones; myosin
MeSH headings : Bronchi / pathology; Epithelial Cells / cytology; Gene Expression Regulation; HSP70 Heat-Shock Proteins / chemistry; Humans; Intracellular Signaling Peptides and Proteins / metabolism; Membrane Proteins / metabolism; Models, Biological; Molecular Chaperones; Mucins / metabolism; Myosin Heavy Chains / chemistry; Myosin Type V / chemistry; Myristoylated Alanine-Rich C Kinase Substrate; Protein Binding; Protein Isoforms; Tetradecanoylphorbol Acetate / chemistry; Transfection
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) Protein Regulation of Human Neutrophil Migration

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 42(5), 586–594.

By: R. Eckert n, L. Neuder*, J. Park*, K. Adler* & S. Jones*

author keywords: inflammation; adhesion; beta 2 integrin; actin
MeSH headings : Actins / metabolism; CD18 Antigens / metabolism; Cell Adhesion / drug effects; Cell Membrane / drug effects; Cell Membrane / metabolism; Cell Polarity / drug effects; Chemotactic Factors / pharmacology; Chemotaxis, Leukocyte / drug effects; Humans; Intracellular Signaling Peptides and Proteins / metabolism; Membrane Proteins / metabolism; Myristoylated Alanine-Rich C Kinase Substrate; N-Formylmethionine Leucyl-Phenylalanine / pharmacology; Neutrophils / cytology; Neutrophils / drug effects; Neutrophils / metabolism; Peptides / pharmacology; Tetradecanoylphorbol Acetate / pharmacology
Sources: Web Of Science, ORCID
Added: August 6, 2018

2008 article

A potential role for airway epithelial cell mucin genes in fibrogenesis.

American Journal of Respiratory and Critical Care Medicine, Vol. 177, p. A727.

By: J. Park, A. Crews, S. Alper, D. Schwartz & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2008 article

MARCKS protein regulation of mucin secretion in airway epithelial cells: binding of MARCKS to chaperones and to MyosinV.

American Journal of Respiratory and Critical Care Medicine, Vol. 177, p. A993.

By: K. Lin, F. J. J., . S. & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

MARCKS regulation of mucin secretion by airway epithelial cells in vitro: interactions with chaperone proteins.

American Journal of Respiratory Cell and Molecular Biology, 102, 949–955.

By: J. Park, S. Fang, A. Crews, K. Lin & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

MARCKS regulation of mucin secretion by airway epithelium in vitro - Interaction with chaperones

American Journal of Respiratory Cell and Molecular Biology, 39(1), 68–76.

By: J. Park, S. Fang, A. Crews, K. Lin & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2008 review

Protease-activated receptor-2 (PAR-2) is a weak enhancer of mucin secretion by human bronchial epithelial cells in vitro

[Review of ]. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 40(6-7), 1379–1388.

By: K. Lin n, J. Park n, A. Crews n, Y. Li n & K. Adler n

author keywords: PAR-2; mucin; airway; secretion
MeSH headings : Bronchi / cytology; Cell Culture Techniques; Cell Line, Transformed; Cell Line, Tumor; Cell Transformation, Viral; Cells, Cultured; Dose-Response Relationship, Drug; Epithelial Cells / cytology; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Humans; Mucins / genetics; Mucins / metabolism; Oligopeptides / chemical synthesis; Oligopeptides / chemistry; Oligopeptides / pharmacology; Papillomaviridae / physiology; RNA, Small Interfering / pharmacology; Receptor, PAR-2 / agonists; Receptor, PAR-2 / genetics; Receptor, PAR-2 / metabolism; Respiratory Mucosa / cytology; Respiratory Mucosa / metabolism; Time Factors; Transfection
Source: Web Of Science
Added: August 6, 2018

2007 article

Anti-inflammatory effects of budesonide and formoterol in primary cultures of human airway epithelial cells.

404nOtfound, Vol. 175, p. A178.

By: J. Park, S. Takashi, A. Crews, A. Miller-Larsson & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

Protein kinase C delta regulates airway mucin secretion via phosphorylation of MARCKS protein

AMERICAN JOURNAL OF PATHOLOGY, 171(6), 1822–1830.

By: J. Park n, A. Crews n, W. Lampe n, S. Fang n, J. Park n & K. Adler n

MeSH headings : Acetophenones / pharmacology; Benzopyrans / pharmacology; Bronchi / drug effects; Bronchi / enzymology; Bronchi / metabolism; Bryostatins / pharmacology; Cell Line; Enzyme Activation; Epithelial Cells / drug effects; Epithelial Cells / enzymology; Epithelial Cells / metabolism; Humans; Intracellular Signaling Peptides and Proteins / metabolism; Membrane Proteins / metabolism; Mucins / metabolism; Myristoylated Alanine-Rich C Kinase Substrate; Phosphorylation; Protein Kinase C-delta / antagonists & inhibitors; Protein Kinase C-delta / genetics; Protein Kinase C-delta / physiology; Protein Kinase Inhibitors / pharmacology; Tetradecanoylphorbol Acetate / pharmacology
Source: Web Of Science
Added: August 6, 2018

2007 article

Proteomic analysis of mucin granule membrane-associated proteins in human airway epithelial cells: a mechanistic link between MARCKS and hClCA1?

404nOtfound, Vol. 175, p. A511.

By: K. Raiford, K. Lin, J. Park, S. Fang, A. Crews & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2006 article

Regulation of airway mucin secretion by MARCKS protein involves the chaperones heat shock protein 70 and Cysteine string protein.

404nOtfound, Vol. 3, p. 493a.

By: J. Park n, S. Fang* & K. Adler*

MeSH headings : Blotting, Western; Bronchi / cytology; Bronchi / metabolism; HSP40 Heat-Shock Proteins / metabolism; HSP70 Heat-Shock Proteins / metabolism; Humans; Intracellular Signaling Peptides and Proteins / metabolism; Membrane Proteins / metabolism; Mucins / metabolism; Myristoylated Alanine-Rich C Kinase Substrate; Nerve Tissue Proteins / metabolism; Protein Kinase C / metabolism; Respiratory Mucosa / cytology; Respiratory Mucosa / metabolism
Source: NC State University Libraries
Added: August 6, 2018

2005 article

A peptide directed against the N-terminus of MARCKS protein attenuates release of myeloperoxidase (MPO) from human and canine neutrophils in vitro.

404nOtfound, Vol. 2, p. A633.

By: S. Takashi, C. Pettersen, J. Park, S. Fang, N. Akley & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2005 article

Cysteine String Protein is involved in mucin secretion from normal human bronchial epithelial (NHBE) cells in vitro.

404nOtfound, Vol. 2, p. A215.

By: J. Park, S. Fang & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2004 article

Small interfering RNA?s directed against MARCKS protein and Heat Shock Protein 70 (Hsp70) attenuate mucin secretion in human airway epithelial cells in vitro.

American Journal of Respiratory and Critical Care Medicine, Vol. 169, p. A712.

By: S. Fang, J. Park & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2003 article

Activation of protease-activated receptors?2 (PAR-2) is not associated with enhanced mucin secretion by well-differentiated normal human bronchial epithelial cells in vitro.

American Journal of Respiratory and Critical Care Medicine, Vol. 167, p. A204.

By: K. Lin, J. Park, Y. Li & K. Adler

Source: NC State University Libraries
Added: August 6, 2018