Javid P Mohammed

Works (8)

Updated: February 13th, 2024 05:00

2024 article

Evaluation of Adjuvant Effect of Cytosine-Guanosine-Oligodeoxynucleotide in Meat-Type Chickens Coadministered In Ovo with Herpesvirus of Turkey Vaccine

Boone, A. C., Kulkarni, R. R., Cortes, A. L., Gaghan, C., Mohammed, J., Villalobos, T., … Gimeno, I. M. (2024, February 1). Viral Immunology, Vol. 2.

By: A. Boone n, R. Kulkarni n , A. Cortes n, C. Gaghan n, J. Mohammed*, T. Villalobos*, J. Esandi*, I. Gimeno n 

author keywords: herpesvirus of turkey; toll-like receptor 21; cellular immunity; immunocompetence; in ovo vaccination; chickens
MeSH headings : Animals; Chickens; CD8-Positive T-Lymphocytes; CD28 Antigens; Adjuvants, Immunologic; Vaccines; Herpesviridae; Oligodeoxyribonucleotides; Meat
topics (OpenAlex): Immune Response and Inflammation; Herpesvirus Infections and Treatments; Immune Cell Function and Interaction
TL;DR: Adding cytosine-guanosine oligodeoxynucleotides (CpG ODNs) to the HVT vaccine could enhance the adjuvant effect of HVT, and CpG ODN administration in ovo with or without HVT significantly increased frequencies of activated CD4+ and CD8+ T cells. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 2, 2024

2022 article

Avian Macrophage Responses to Virulent and Avirulent Clostridium perfringens

Kulkarni, R. R., Gaghan, C., & Mohammed, J. (2022, January 15). Pathogens, Vol. 1.

By: R. Kulkarni n , C. Gaghan n & J. Mohammed n

author keywords: macrophages; Clostridium perfringens; virulence; chicken; necrotic enteritis; immune response
topics (OpenAlex): Clostridium difficile and Clostridium perfringens research; Pharmacological Effects of Natural Compounds; Gut microbiota and health
TL;DR: Macrophage interaction with C. perfringens can lead to cellular activation and, the ability of this pathogen to induce macrophage responses may depend on its level of virulence (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 17, 2022

2022 article

Characterization of vaccine-induced immune responses against coccidiosis in broiler chickens

Gaghan, C., Adams, D., Mohammed, J., Crespo, R., Livingston, K., & Kulkarni, R. R. (2022, May 25). Vaccine, Vol. 40, pp. 3893–3902.

By: C. Gaghan n, D. Adams  n, J. Mohammed n, R. Crespo n , K. Livingston n & R. Kulkarni n 

author keywords: Coccidiosis; Eimeria; Vaccine; Immunity; Immune response
MeSH headings : Animals; Chickens; Coccidiosis / prevention & control; Coccidiosis / veterinary; Eimeria; Eimeria tenella; Immunity; Oocysts; Poultry Diseases; Protozoan Vaccines; Toll-Like Receptor 2
topics (OpenAlex): Coccidia and coccidiosis research; Veterinary medicine and infectious diseases; Animal Nutrition and Physiology
TL;DR: Findings suggest that TLR21 and TLR2 may be involved in the immune cell recognition of Eimeria parasites and that the vaccine can induce a robust macrophage activation leading to a T helper-1 dominated protective response at both local and systemic lymphoid tissues. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: May 27, 2022

2022 article

Enumeration and speciation of coccidia affecting turkeys using flow cytometry method

Boyett, T., Crespo, R., Vinueza, V. C., Gaghan, C., Mohammed, J. P., & Kulkarni, R. R. (2022, May 13). The Journal of Applied Poultry Research, Vol. 31, p. 100270.

By: T. Boyett n, R. Crespo n , V. Vinueza n, C. Gaghan n, J. Mohammed n & R. Kulkarni n 

author keywords: Eimeria; coccidiosis; turkey; flow cytometry; diagnosis
topics (OpenAlex): Coccidia and coccidiosis research; Parasitic Infections and Diagnostics; Veterinary medicine and infectious diseases
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Added: May 13, 2022

2022 journal article

Long‐term effects of ciclosporin and oclacitinib on mediators of tolerance, regulatory T‐cells, IL‐10 and TGF‐β, in dogs with atopic dermatitis

Veterinary Dermatology, 34(2), 107–114.

By: I. Herrmann n , L. Mamo n, J. Holmes n, J. Mohammed n, K. Murphy n  & P. Bizikova n 

author keywords: canine atopic dermatitis; ciclosporin; oclacitinib; T regulatory cell
MeSH headings : Dogs; Animals; Cyclosporine / therapeutic use; T-Lymphocytes, Regulatory; Interleukin-10; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / veterinary; Transforming Growth Factor beta1 / therapeutic use; Transforming Growth Factor beta / therapeutic use; Immune Tolerance; Dog Diseases / drug therapy
topics (OpenAlex): Dermatology and Skin Diseases; T-cell and B-cell Immunology; Asthma and respiratory diseases
TL;DR: Lower Treg cell percentages in the CSA-treated dogs suggest an impact of this drug on this cell population; however, it does not necessarily mean that it diminishes tolerance. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: January 3, 2023

2021 article

A flow cytometric method for enumeration and speciation of coccidia affecting broiler chickens

Adams, D. S., Kulkarni, R. R., Mohammed, J. P., & Crespo, R. (2021, November 30). Veterinary Parasitology, Vol. 301, p. 109634.

By: D. Adams  n, R. Kulkarni n , J. Mohammed n & R. Crespo n 

Contributors: D. Adams  n, R. Kulkarni n , J. Mohammed n & R. Crespo n 

author keywords: Flow cytometry; Eimeria; Coccidiosis; Oocyst; Quantification
MeSH headings : Animals; Chickens; Coccidiosis / veterinary; Eimeria / genetics; Flow Cytometry / veterinary; Poultry Diseases; Real-Time Polymerase Chain Reaction / veterinary
topics (OpenAlex): Coccidia and coccidiosis research; Helminth infection and control; Veterinary medicine and infectious diseases
TL;DR: It is suggested that non-antibody based Flow Cytometry technique can be successful in the simultaneous enumeration and speciation of coccidia and other Eimeria species. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: December 1, 2021

2021 article

Intestinal changes and immune responses during Clostridium perfringens-induced necrotic enteritis in broiler chickens

Daneshmand, A., Kermanshahi, H., Mohammed, J., Sekhavati, M. H., Javadmanesh, A., Ahmadian, M., … Kulkarni, R. R. (2021, December 7). Poultry Science, Vol. 12, p. 101652.

By: A. Daneshmand *, H. Kermanshahi *, J. Mohammed n, M. Sekhavati *, A. Javadmanesh *, M. Ahmadian*, M. Alizadeh *, J. Razmyar *, R. Kulkarni n 

author keywords: Necrotic enteritis; Clostridium perfringens; broiler chicken; histomorphometry; immune response
MeSH headings : Animals; Chickens; Clostridium Infections / pathology; Clostridium Infections / veterinary; Clostridium perfringens / physiology; Diet / veterinary; Enteritis / pathology; Enteritis / veterinary; Escherichia coli; Immunity; Necrosis / veterinary; Poultry Diseases
topics (OpenAlex): Clostridium difficile and Clostridium perfringens research; Antimicrobial Resistance in Staphylococcus; Antimicrobial Peptides and Activities
TL;DR: C. perfringens, while inducing epithelial damage and changes in microbiota, can also trigger host immune responses, and NE reproduction methods using coccidia with or without the wheat-based dietary predisposition seem to facilitate an optimal NE reproduction in broiler chickens. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: December 7, 2021

2019 article

Genetic and functional data identifying Cd101 as a type 1 diabetes (T1D) susceptibility gene in nonobese diabetic (NOD) mice

Mattner, J., Mohammed, J. P., Fusakio, M. E., Giessler, C., Hackstein, C.-P., Opoka, R., … Wicker, L. S. (2019, June 14). PLoS Genetics.

By: J. Mattner *, J. Mohammed*, M. Fusakio *, C. Giessler*, C. Hackstein *, R. Opoka *, M. Wrage *, R. Schey* ...

MeSH headings : Animals; Antigens, CD / genetics; Antigens, Ly / genetics; CD4-Positive T-Lymphocytes / metabolism; CD8-Positive T-Lymphocytes / metabolism; Diabetes Mellitus, Type 1 / genetics; Diabetes Mellitus, Type 1 / pathology; Gene Expression Regulation / genetics; Genetic Predisposition to Disease; Haplotypes / genetics; Humans; Lymph Nodes / metabolism; Lymph Nodes / pathology; Mice; Mice, Inbred NOD; Mice, Knockout; Myeloid Cells / immunology; Myeloid Cells / metabolism; Pancreas / metabolism; Pancreas / pathology; T-Lymphocytes, Regulatory / immunology; T-Lymphocytes, Regulatory / metabolism
topics (OpenAlex): Diabetes and associated disorders; Immune Cell Function and Interaction; T-cell and B-cell Immunology
TL;DR: The results connect the Cd101 haplotype-dependent protection from T1D to an anti-diabetogenic function of CD101-expressing Tregs and Gr1-positive myeloid cells and confirm the identity of Cd 101 as Idd10. (via Semantic Scholar)
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Source: Web Of Science
Added: July 29, 2019

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