Jack Patrick Ryan

College of Sciences

Works (2)

Updated: December 18th, 2023 07:50

2022 article

Stability and Dissociation of Adeno-Associated Viral Capsids by Variable Temperature-Charge Detection-Mass Spectrometry

Kostelic, M. M., Ryan, J. P., Brown, L. S., Jackson, T. W., Hsieh, C.-C., Zak, C. K., … Marty, M. T. (2022, August 18). ANALYTICAL CHEMISTRY, Vol. 8.

By: M. Kostelic*, J. Ryan n, L. Brown*, T. Jackson*, C. Hsieh *, C. Zak*, H. Sanders *, Y. Liu * ...

MeSH headings : Capsid / chemistry; Capsid Proteins / chemistry; Dependovirus / chemistry; Mass Spectrometry; Temperature
TL;DR: This new approach better characterizes the thermal dissociation of AAVs, providing the simultaneous measurement of the stabilities and dissociation pathways of different subpopulations, and observed that pH stress caused a major decrease in thermal stability. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: September 12, 2022

2022 journal article

Surface Modified Nano-Electrospray Needles Improve Sensitivity for Native Mass Spectrometry

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 33(6), 1031–1037.

By: M. Kostelic*, C. Hsieh *, H. Sanders *, C. Zak*, J. Ryan n, E. Baker n , C. Aspinwall *, M. Marty *

author keywords: native mass spectrometry; charge detection mass spectrometry; electrospray ionization; silane chemistry
MeSH headings : Needles; Proteins / analysis; Spectrometry, Mass, Electrospray Ionization / methods
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Sources: Web Of Science, NC State University Libraries
Added: June 20, 2022

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