Jack Wang
Jack P. Wang is an Assistant Professor in the Forest Biotechnology Group, Department of Forestry and Environmental Resources, College of Natural Resources at North Carolina State University. Jack received his B.S. degree in Biology and Chemistry from Waikato University, New Zealand in 2006, and completed his Ph.D. at North Carolina State University in 2012, under the mentorship of Dr. Vincent Chiang and Dr. Ron Sederoff. Jack is a forestry scientist with research experience in molecular genetics and biotechnology, particularly the integrative genomic and genetic analysis of plant metabolism for tree growth, development, and defense against biotic and abiotic stresses. Some highlights of his recent research include an unprecedented quantitative systematic analysis of the response to genetic regulation in the model tree species (Populus trichocarpa), with important immediate implications for plant growth and adaptation, as well as biofuels and biomaterials (published in 2018 in Nature Communications); demonstrating that protein phosphorylation acts as an on/off switch for AldOMT, a central enzyme in monolignol biosynthesis (published in 2015 in PNAS); characterizing the hetero-tetrameric 4CL enzyme complex formation, regulation and numerical modeling (published in 2014 in Plant Cell); and establishing a proteomic-based predictive kinetic metabolic-flux (PKMF) model of the monolignol biosynthetic pathway (published in 2014 in Plant Cell). This PKMF model predicts how monolignol pathway enzymes affect lignin content and composition, explains a long-standing paradox regarding the regulation of monolignol subunit ratios in lignin, and reveals novel mechanisms involved in the regulation of lignin biosynthesis.
Works (49)
Updated: August 18th, 2023 21:18
2023 article
Cell-type-specific PtrWOX4a and PtrVCS2 form a regulatory nexus with a histone modification system for stem cambium development in Populus trichocarpa
Dai, X., Zhai, R., Lin, J., Wang, Z., Meng, D., Li, M., … Li, W. (2023, January 9). NATURE PLANTS.
MeSH headings : Cambium / genetics; Populus / genetics; Epigenesis, Genetic; Histone Code; Wood; Gene Expression Regulation, Plant
www.nature.com (publisher PDF)
Source: Web Of Science
Added: January 23, 2023
2023 journal article
Fermentative conversion of unpretreated plant biomass: A thermophilic threshold for indigenous microbial growth
BIORESOURCE TECHNOLOGY, 367.
author keywords: Thermophiles; Lignocellulose; Consolidated bioprocessing; Caldicellulosiruptor bescii; Acetivibrio thermocellus
MeSH headings : Biomass; Fermentation; Lignin / chemistry; Clostridium thermocellum / metabolism; Plants / metabolism
Sources: Web Of Science, ORCID
Added: January 17, 2023
2023 journal article
Multiplex CRISPR editing of wood for sustainable fiber production.
Science (New York, N.Y.), 7.
Source: ORCID
Added: August 9, 2023
2022 journal article
Plant biomass fermentation by the extreme thermophile Caldicellulosiruptor bescii for co-production of green hydrogen and acetone: Technoeconomic analysis
BIORESOURCE TECHNOLOGY, 348.
author keywords: Acetone; Green hydrogen; Caldicellulosiruptor bescii; Extreme thermophiles; Technoeconomic analysis
MeSH headings : Acetone; Biomass; Caldicellulosiruptor; Fermentation; Hydrogen; Lignin / chemistry
Sources: Web Of Science, ORCID
Added: April 25, 2022
2022 article
Dimerization of PtrMYB074 and PtrWRKY19 mediates transcriptional activation of PtrbHLH186 for secondary xylem development in Populus trichocarpa
Liu, H., Gao, J., Sun, J., Li, S., Zhang, B., Wang, Z., … Li, W. (2022, March 3). NEW PHYTOLOGIST, Vol. 5.
author keywords: Populus trichocarpa; protein-protein interaction; secondary xylem development; transcription factor; wood formation
MeSH headings : Cell Wall / metabolism; Dimerization; Gene Expression Regulation, Plant; Plant Proteins / genetics; Plant Proteins / metabolism; Populus; Transcriptional Activation; Wood; Xylem / metabolism
Sources: Web Of Science, ORCID
Added: March 21, 2022
2022 journal article
Enhancing HR Frequency for Precise Genome Editing in Plants
FRONTIERS IN PLANT SCIENCE, 13.
author keywords: homologous recombination; homology-directed repair; gene targeting; donor template; programmable nucleases
Sources: Web Of Science, ORCID
Added: May 31, 2022
2022 journal article
p A PtrLBD39-mediated transcriptional network regulates tension wood formation in Populus trichocarpa
PLANT COMMUNICATIONS, 3(1).
author keywords: tension wood; cellulose; lignin; transcriptional regulatory network; transcriptomics; chromatin immunoprecipitation sequencing
MeSH headings : Biomechanical Phenomena; Gene Expression Regulation, Plant / physiology; Gene Regulatory Networks / physiology; Genes, Plant / genetics; Genes, Plant / physiology; Laser Capture Microdissection; Populus / genetics; Populus / physiology; Wood / genetics; Wood / physiology; Xylem
Sources: Web Of Science, ORCID
Added: January 31, 2022
2021 journal article
A multiscale model of lignin biosynthesis for predicting bioenergy traits in Populus trichocarpa
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 19, 168–182.
author keywords: Lignin biosynthesis; Multiscale modeling; Cross-regulatory influences; Random forests
Sources: Web Of Science, ORCID
Added: September 20, 2021
2021 article
CRISPR-Cas9 editing of CAFFEOYL SHIKIMATE ESTERASE 1 and 2 shows their importance and partial redundancy in lignification in Populus tremula x P. alba
Vries, L., Brouckaert, M., Chanoca, A., Kim, H., Regner, M. R., Timokhin, V. I., … Boerjan, W. (2021, August 6). PLANT BIOTECHNOLOGY JOURNAL, Vol. 11.
author keywords: poplar; CRISPR-Cas9; CSE; lignin; phenylpropanoids; metabolic engineering
MeSH headings : CRISPR-Cas Systems / genetics; Carboxylesterase; Gene Expression Regulation, Plant; Lignin / metabolism; Plants, Genetically Modified / genetics; Plants, Genetically Modified / metabolism; Populus / genetics; Populus / metabolism
Sources: Web Of Science, ORCID
Added: August 23, 2021
2021 journal article
Enzyme Complexes of Ptr4CL and PtrHCT Modulate Co-enzyme A Ligation of Hydroxycinnamic Acids for Monolignol Biosynthesis in Populus trichocarpa
FRONTIERS IN PLANT SCIENCE, 12.
author keywords: protein interaction; monolignol biosynthesis; wood formation; Populus trichocarpa; BiFC; metabolic flux
Sources: Web Of Science, ORCID
Added: November 8, 2021
2021 journal article
Thermophilic microbial deconstruction and conversion of natural and transgenic lignocellulose
Environmental Microbiology Reports, 13(3), 272–293.
MeSH headings : Biomass; Lignin / chemistry; Plants / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: April 12, 2021
2021 journal article
Transcriptional reprogramming of xylem cell wall biosynthesis in tension wood
PLANT PHYSIOLOGY, 186(1), 250–269.
MeSH headings : Cell Wall / metabolism; Gene Expression Regulation, Plant; Populus / anatomy & histology; Populus / genetics; Transcription, Genetic; Wood / genetics; Wood / metabolism; Xylem / metabolism
Sources: ORCID, Web Of Science
Added: May 27, 2021
2020 journal article
MYB Transcription Factor161 Mediates Feedback Regulation of Secondary wall-associated NAC-Domain1 Family Genes for Wood Formation
Plant Physiology, 9, pp.01033.2020.
MeSH headings : Cell Enlargement; Cell Proliferation; Cell Wall / metabolism; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Genes, Plant; Genetic Variation; Genotype; Plant Proteins / metabolism; Populus / genetics; Populus / growth & development; Populus / metabolism; Transcription Factors / genetics; Transcription Factors / metabolism; Wood / growth & development; Xylem / metabolism
Source: ORCID
Added: November 3, 2020
2020 journal article
Modeling cross-regulatory influences on monolignol transcripts and proteins under single and combinatorial gene knockdowns in Populus trichocarpa
PLOS Computational Biology.
Ed(s): S. Roy
MeSH headings : Computational Biology / methods; Gene Expression Regulation, Plant / genetics; Gene Knockdown Techniques / methods; Lignin / biosynthesis; Lignin / genetics; Lignin / metabolism; Models, Theoretical; Populus / genetics; Wood / genetics
Source: ORCID
Added: April 11, 2020
2020 journal article
Monolignol Benzoates Incorporate into the Lignin of Transgenic Populus trichocarpa Depleted in C3H and C4H
ACS Sustainable Chemistry and Engineering, 8(9), 3644–3654.
author keywords: poplar; 2D NMR; HSQC; enzyme; p-hydroxybenzoate; biomass; cytochrome P450
Source: ORCID
Added: April 2, 2020
2020 review
Regulation of Lignin Biosynthesis by Post-translational Protein Modifications
[Review of ]. FRONTIERS IN PLANT SCIENCE, 11.
author keywords: lignin; lignification; proteins; PTMs; SCW; trees; wood formation
Sources: Web Of Science, ORCID
Added: August 10, 2020
2020 journal article
Tracheid Associated Transcription Factors in Loblolly Pine.
Tree Physiology, 2.
MeSH headings : Pinus taeda; Transcription Factors / genetics
Source: ORCID
Added: April 2, 2020
2020 journal article
Use of the lignocellulose-degrading bacterium Caldicellulosiruptor bescii to assess recalcitrance and conversion of wild-type and transgenic poplar
BIOTECHNOLOGY FOR BIOFUELS, 13(1).
author keywords: Caldicellulosiruptor; Extreme thermophiles; Lignocellulose; Biofuel; Poplar
Sources: Web Of Science, ORCID
Added: April 6, 2020
2019 journal article
A novel synthetic-genetic-array-based yeast one-hybrid system for high discovery rate and short processing time
GENOME RESEARCH, 29(8), 1343–1351.
MeSH headings : Animals; DNA / genetics; DNA / metabolism; Gene Expression Regulation; Gene Regulatory Networks; Genetic Markers; Humans; Meiosis; Microarray Analysis / instrumentation; Microarray Analysis / methods; Plasmids / chemistry; Plasmids / metabolism; Ploidies; Populus / cytology; Protein Binding; Protoplasts / cytology; Protoplasts / metabolism; Saccharomyces cerevisiae / genetics; Saccharomyces cerevisiae / metabolism; Time Factors; Transcription Factors / genetics; Transcription Factors / metabolism; Two-Hybrid System Techniques
Sources: Web Of Science, ORCID
Added: September 16, 2019
2019 journal article
CAD1 and CCR2 protein complex formation in monolignol biosynthesis in Populus trichocarpa
NEW PHYTOLOGIST, 222(1), 244–260.
author keywords: co-immunoprecipitation; enzyme activity; monolignol biosynthetic pathway; nuclear magnetic resonance (NMR); Populus trichocarpa; stem-differentiating xylem protein
MeSH headings : Aldehyde Oxidoreductases / genetics; Aldehyde Oxidoreductases / metabolism; Down-Regulation / genetics; Gene Expression Regulation, Plant; Lignin / metabolism; Magnetic Resonance Spectroscopy; Plant Proteins / genetics; Plant Proteins / metabolism; Plants, Genetically Modified; Populus / genetics; Populus / metabolism; RNA Interference; Recombinant Proteins / metabolism; Xylem / metabolism
Sources: ORCID, Web Of Science
Added: December 17, 2018
2019 review
Enzyme-Enzyme Interactions in Monolignol Biosynthesis
[Review of ]. FRONTIERS IN PLANT SCIENCE, 9.
author keywords: monolignol biosynthesis; protein-protein interaction; lignin; enzyme kinetics; BiFC; co-immunoprecipitation
Sources: Web Of Science, ORCID
Added: January 28, 2019
2019 journal article
Flux modeling for monolignol biosynthesis
Current Opinion in Biotechnology, 56, 187–192.
MeSH headings : Biosynthetic Pathways; Kinetics; Lignin / biosynthesis; Metabolic Engineering; Metabolic Flux Analysis; Models, Biological
Sources: ORCID, Crossref
Added: April 24, 2019
2019 journal article
Hierarchical Transcription Factor and Chromatin Binding Network for Wood Formation in Populus trichocarpa
The Plant Cell, 31(3), 602–626.
MeSH headings : Cell Wall / metabolism; Chromatin / genetics; Chromatin / metabolism; Gene Expression Regulation, Developmental / genetics; Gene Expression Regulation, Plant / genetics; Gene Regulatory Networks / genetics; Plant Proteins / genetics; Plant Proteins / metabolism; Populus / genetics; Populus / growth & development; Populus / physiology; Transcription Factors / genetics; Transcription Factors / metabolism; Wood / growth & development
Source: ORCID
Added: April 18, 2019
2019 article
Modeling cross-regulatory influences on monolignol transcripts and proteins under single and combinatorial gene knockdowns in Populus trichocarpa
Matthews, M. L., Wang, J. P., Sederoff, R., Chiang, V. L., & Williams, C. M. (2019, June 19). (Vol. 6). Vol. 6.
Source: ORCID
Added: June 20, 2019
2019 journal article
Quantitative fermentation of unpretreated transgenic poplar by Caldicellulosiruptor bescii
NATURE COMMUNICATIONS, 10(1).
MeSH headings : Biomass; Cellulose / metabolism; Clostridiales / genetics; Clostridiales / metabolism; Ethanol / metabolism; Fermentation; Industrial Microbiology; Lignin / metabolism; Metabolic Engineering; Plants, Genetically Modified / chemistry; Plants, Genetically Modified / genetics; Plants, Genetically Modified / metabolism; Polysaccharides / metabolism; Populus / chemistry; Populus / genetics; Populus / metabolism
Sources: Web Of Science, ORCID
Added: August 26, 2019
2019 review
Systems and Synthetic Biology of Forest Trees: A Bioengineering Paradigm for Woody Biomass Feedstocks
[Review of ]. FRONTIERS IN PLANT SCIENCE, 10.
author keywords: synthetic biology (synbio); systems biology; systems genetics; woody biomass; biorefinery; bioeconomy; lignin biosynthesis; wood formation
Sources: Web Of Science, ORCID
Added: July 8, 2019
2019 journal article
The AREB1 Transcription Factor Influences Histone Acetylation to Regulate Drought Responses and Tolerance in Populus trichocarpa
Plant Cell, 31(3), 663–686.
MeSH headings : Abscisic Acid / metabolism; Acetylation; Droughts; Gene Expression Regulation, Plant; Histone Acetyltransferases / genetics; Histone Acetyltransferases / metabolism; Histones / metabolism; Nucleotide Motifs; Phenotype; Plant Growth Regulators / metabolism; Plant Proteins / genetics; Plant Proteins / metabolism; Populus / genetics; Populus / physiology; Promoter Regions, Genetic / genetics; Protein Processing, Post-Translational; RNA Polymerase II / genetics; RNA Polymerase II / metabolism; Transcription Factors / genetics; Transcription Factors / metabolism; Transcriptional Activation
Source: ORCID
Added: April 24, 2019
2018 journal article
Assessing the impact of the 4CL enzyme complex on the robustness of monolignol biosynthesis using metabolic pathway analysis
PLOS ONE, 13(3), e0193896.
Ed(s): D. Cullen
MeSH headings : Biosynthetic Pathways; Homeostasis; Lignin / biosynthesis; Metabolic Networks and Pathways; Monte Carlo Method; Plant Proteins / metabolism; Populus / enzymology; Populus / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2018 journal article
Improving wood properties for wood utilization through multi-omics integration in lignin biosynthesis
Nature Communications, 9(1), 1579.
MeSH headings : Gene Expression Regulation, Plant; Lignin / biosynthesis; Lignin / genetics; Plants, Genetically Modified / genetics; Populus / genetics; Populus / metabolism; Transcriptome / genetics; Trees / genetics; Trees / metabolism; Wood / chemistry; Wood / physiology; Xylem / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2017 journal article
Reciprocal cross-regulation of VND and SND multigene TF families for wood formation in Populus trichocarpa
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114(45), E9722–E9729.
author keywords: reciprocal cross-regulation; NAC transcription factors; alternative splicing; wood formation; Populus trichocarpa
MeSH headings : Alternative Splicing; Cell Wall / genetics; Cell Wall / metabolism; Cloning, Molecular; DNA, Plant; Gene Expression Regulation, Plant / genetics; Gene Regulatory Networks; Genes, Plant; Homeostasis; Multigene Family; Nuclear Proteins; Plant Leaves / genetics; Plant Leaves / metabolism; Plant Proteins / genetics; Plant Proteins / metabolism; Plant Shoots / genetics; Plant Shoots / metabolism; Populus / genetics; Populus / metabolism; Recombinant Proteins / genetics; Transcription Factors / genetics; Transcription Factors / metabolism; Transcriptional Activation / genetics; Transcriptome; Wood / genetics; Wood / growth & development; Xylem / genetics; Xylem / growth & development
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
Tissue and cell-type co-expression networks of transcription factors and wood component genes in Populus trichocarpa
PLANTA, 245(5), 927–938.
author keywords: Wood formation; Transcriptome; Fiber cells; Vessel elements; Cell wall biosynthesis; Co-expression network
MeSH headings : Cell Wall / metabolism; Cellulose / metabolism; Cluster Analysis; Gene Expression Regulation, Plant; Lignin / metabolism; Molecular Sequence Annotation; Organ Specificity; Phloem / genetics; Phloem / growth & development; Plant Leaves / genetics; Plant Leaves / growth & development; Plant Proteins / genetics; Populus / genetics; Populus / growth & development; Sequence Analysis, RNA; Transcription Factors / genetics; Transcriptome; Wood / genetics; Wood / growth & development; Xylem / genetics; Xylem / growth & development
Sources: Web Of Science, ORCID
Added: August 6, 2018
2016 chapter
A Proteomic-Based Quantitative Analysis of the Relationship Between Monolignol Biosynthetic Protein Abundance and Lignin Content Using TransgenicPopulus trichocarpa
In V. C. Kumi Yoshida & S. Quideau (Eds.), Recent Advances in Polyphenol Research (Vol. 5, pp. 89–107).
Ed(s): V. Kumi Yoshida & S. Quideau
Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018
2016 journal article
A cell wall-bound anionic peroxidase, PtrPO21, is involved in lignin polymerization in Populus trichocarpa
Tree Genetics & Genomes, 12(2).
author keywords: Lignin polymerization; Populus trichocarpa; Lignin peroxidase; LC-MS/MS; Lignin systems biology
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2015 journal article
4-Coumaroyl and Caffeoyl Shikimic Acids Inhibit 4-Coumaric Acid: Coenzyme A Ligases and Modulate Metabolic Flux for 3-Hydroxylation in Monolignol Biosynthesis of Populus trichocarpa
MOLECULAR PLANT, 8(1), 176–187.
author keywords: monolignol biosynthesis; Populus trichocarpa; metabolic flux; reaction and inhibition kinetics; LC-MS/MS; 4-coumaroyl and caffeoyl shikimic acids
MeSH headings : Acyl Coenzyme A / metabolism; Coenzyme A Ligases / metabolism; Coumaric Acids / metabolism; Coumaric Acids / pharmacology; Hydroxylation / drug effects; Plant Proteins / metabolism; Populus / drug effects; Populus / enzymology; Populus / metabolism; Propionates; Shikimic Acid / pharmacology
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Comparative proteomic analysis of Populus trichocarpa early stem from primary to secondary growth
JOURNAL OF PROTEOMICS, 126, 94–108.
author keywords: Proteomics; Early stem development; Secondary growth; Populus trichocarpa
MeSH headings : Plant Proteins / biosynthesis; Plant Stems / metabolism; Populus / metabolism; Proteome / biosynthesis; Proteomics
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Elucidation of Xylem-Specific Transcription Factors and Absolute Quantification of Enzymes Regulating Cellulose Biosynthesis in Populus trichocarpa
JOURNAL OF PROTEOME RESEARCH, 14(10), 4158–4168.
author keywords: shotgun discovery proteomics; absolute quantification; PC-IDMS; cellulose biosynthesis; transcription factor; targeted mass spectrometiry; SRM
MeSH headings : Carbohydrate Metabolism; Cellulose / biosynthesis; Cellulose / genetics; Chromatography, Liquid; Gene Expression Regulation, Plant; Molecular Sequence Annotation; Plant Proteins / genetics; Plant Proteins / isolation & purification; Plant Proteins / metabolism; Populus / genetics; Populus / metabolism; Proteome / genetics; Proteome / isolation & purification; Proteome / metabolism; Proteomics; Tandem Mass Spectrometry; Transcription Factors / genetics; Transcription Factors / isolation & purification; Transcription Factors / metabolism; Wood / chemistry; Wood / metabolism; Xylem / genetics; Xylem / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Phosphorylation is an on/off switch for 5-hydroxyconiferaldehyde O-methyltransferase activity in poplar monolignol biosynthesis
Proceedings of the National Academy of Sciences, 112(27), 8481–8486.
author keywords: AldOMT; COMT; lignin; phosphoproteomics; phosphoregulation
MeSH headings : Acrolein / analogs & derivatives; Acrolein / metabolism; Amino Acid Sequence; Binding Sites / genetics; Biocatalysis; Catechols / metabolism; Chromatography, Liquid; Electrophoresis, Polyacrylamide Gel; Green Fluorescent Proteins / genetics; Green Fluorescent Proteins / metabolism; Isoenzymes / genetics; Isoenzymes / metabolism; Lignin / biosynthesis; Methyltransferases / genetics; Methyltransferases / metabolism; Microscopy, Confocal; Molecular Sequence Data; Mutation; Phosphoproteins / metabolism; Phosphorylation; Plant Proteins / genetics; Plant Proteins / metabolism; Populus / enzymology; Populus / genetics; Populus / metabolism; Proteomics / methods; Protoplasts / enzymology; Protoplasts / metabolism; Sequence Homology, Amino Acid; Tandem Mass Spectrometry
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2014 journal article
A simple improved-throughput xylem protoplast system for studying wood formation
NATURE PROTOCOLS, 9(9), 2194–2205.
MeSH headings : Cell Wall / metabolism; Gene Expression Regulation, Plant / genetics; Gene Regulatory Networks / genetics; Green Fluorescent Proteins; Populus / cytology; Populus / growth & development; Protoplasts / metabolism; Transfection / methods; Wood / cytology; Wood / growth & development; Xylem / chemistry
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Complete Proteomic-Based Enzyme Reaction and Inhibition Kinetics Reveal How Monolignol Biosynthetic Enzyme Families Affect Metabolic Flux and Lignin in Populus trichocarpa
The Plant Cell, 26(3), 894–914.
MeSH headings : Kinetics; Lignin / metabolism; Mass Spectrometry; Plant Proteins / metabolism; Polymorphism, Single Nucleotide; Populus / metabolism; Proteome
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2014 review
Plant biotechnology for lignocellulosic biofuel production
[Review of ]. PLANT BIOTECHNOLOGY JOURNAL, 12(9), 1174–1192.
author keywords: biofuel; biotechnology; cell wall; lignocellulose
MeSH headings : Biofuels; Biotechnology / methods; Cell Wall / metabolism; Lignin / metabolism; Plants / enzymology; Plants / metabolism; Protein Engineering
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Systems Biology of Lignin Biosynthesis in Populus trichocarpa: Heteromeric 4-Coumaric Acid:Coenzyme A Ligase Protein Complex Formation, Regulation, and Numerical Modeling
The Plant Cell, 26(3), 876–893.
MeSH headings : Coenzyme A Ligases / genetics; Coenzyme A Ligases / metabolism; Coumaric Acids / metabolism; Immunoprecipitation; Lignin / biosynthesis; Mass Spectrometry; Models, Biological; Populus / metabolism; Propionates; RNA, Messenger / genetics; Substrate Specificity; Systems Biology
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2013 journal article
Monolignol Pathway 4-Coumaric Acid: Coenzyme A Ligases in Populus trichocarpa: Novel Specificity, Metabolic Regulation, and Simulation of Coenzyme A Ligation Fluxes
PLANT PHYSIOLOGY, 161(3), 1501–1516.
MeSH headings : Allosteric Regulation / drug effects; Binding Sites; Biosynthetic Pathways / drug effects; Blotting, Western; Caffeic Acids / pharmacology; Coenzyme A / metabolism; Coenzyme A Ligases / antagonists & inhibitors; Coenzyme A Ligases / metabolism; Computer Simulation; Coumaric Acids / chemistry; Coumaric Acids / metabolism; Coumaric Acids / pharmacology; Kinetics; Lignin / biosynthesis; Lignin / chemistry; Phenylpropionates / metabolism; Phosphoproteins / metabolism; Phosphorylation / drug effects; Plant Extracts; Populus / drug effects; Populus / enzymology; Propionates; Proteomics; Recombinant Fusion Proteins / metabolism; Sequence Homology, Amino Acid; Substrate Specificity / drug effects; Xylem / drug effects; Xylem / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018
2013 journal article
Regulation of phenylalanine ammonia-lyase (PAL) gene family in wood forming tissue of Populus trichocarpa
Planta, 238(3), 487–497.
MeSH headings : Gene Expression Regulation, Plant / physiology; Mass Spectrometry; Phenylalanine Ammonia-Lyase / metabolism; Populus / enzymology; Populus / metabolism
Sources: NC State University Libraries, ORCID
Added: August 6, 2018
2013 journal article
Understanding the Role of Proteolytic Digestion on Discovery and Targeted Proteomic Measurements Using Liquid Chromatography Tandem Mass Spectrometry and Design of Experiments
JOURNAL OF PROTEOME RESEARCH, 12(12), 5820–5829.
author keywords: design of experiments; proteolytic digestion; LC-MS/MS; Populus trichocarpa
MeSH headings : Amino Acid Sequence; Animals; Cattle; Chromatography, Liquid / standards; Factor Analysis, Statistical; Hydrogen-Ion Concentration; Isotope Labeling; Molecular Sequence Annotation; Molecular Sequence Data; Peptide Fragments / chemistry; Peptide Fragments / isolation & purification; Plant Proteins / chemistry; Plant Proteins / isolation & purification; Populus / chemistry; Protein Stability; Proteolysis; Proteomics / methods; Proteomics / standards; Research Design; Swine; Tandem Mass Spectrometry / standards; Trypsin / chemistry; Xylem / chemistry
Sources: Web Of Science, ORCID
Added: August 6, 2018
2012 journal article
Comprehensive Quantification of Monolignol-Pathway Enzymes in Populus trichocarpa by Protein Cleavage Isotope Dilution Mass Spectrometry
Journal of Proteome Research, 11(6), 3390–3404.
author keywords: quantification; isotope dilution mass spectrometry; selected reaction monitoring; filter-aided sample preparation; monolignol biosynthesis
MeSH headings : Amino Acid Sequence; Biosynthetic Pathways; Isotope Labeling; Molecular Sequence Data; Plant Proteins / chemistry; Plant Proteins / metabolism; Populus / enzymology; Proteome / chemistry; Proteome / metabolism; Reference Standards; Spectrometry, Mass, Electrospray Ionization / standards; Xylem / enzymology
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2012 journal article
Functional redundancy of the two 5-hydroxylases in monolignol biosynthesis of Populus trichocarpa: LC-MS/MS based protein quantification and metabolic flux analysis
PLANTA, 236(3), 795–808.
author keywords: Lignin; Syringyl lignin; Angiosperm; Kinetics; Subcellular localization
MeSH headings : Cloning, Molecular; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Hydroxylation; Kinetics; Lignin / analysis; Lignin / biosynthesis; Mixed Function Oxygenases / metabolism; Plants, Genetically Modified; Populus / metabolism; Xylem / enzymology; Yeasts / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018
2011 journal article
Down-regulation of glycosyltransferase 8D genes in Populus trichocarpa caused reduced mechanical strength and xylan content in wood
TREE PHYSIOLOGY, 31(2), 226–236.
author keywords: glycosyltransferase; Populus trichocarpa; wood formation; xylan
MeSH headings : Arabidopsis / genetics; Arabidopsis / metabolism; Cell Wall / metabolism; Down-Regulation; Elastic Modulus; Gene Expression Regulation, Plant; Genes, Plant; Genetic Variation; Glycosyltransferases / genetics; Glycosyltransferases / metabolism; Plant Stems / chemistry; Plants, Genetically Modified / genetics; Plants, Genetically Modified / metabolism; Populus / genetics; Populus / metabolism; Stress, Mechanical; Transcription Factors; Wood / analysis; Xylans / biosynthesis; Xylans / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018
2007 journal article
A novel O-methyl transferase-like gene with a drastic ectopic expression in response to tension wood formation in Populus trichocarpa
Cellulose Chemistry and Technology, 41(9-10), 521–528. http://www.scopus.com/inward/record.url?eid=2-s2.0-60749092120&partnerID=MN8TOARS
Source: ORCID
Added: December 17, 2018
2007 journal article
A novel O-methyl transferase-like gene with drastic ectopic expression in response to tension wood formation in Populus trichocarpa
Cellulose Chemistry and Technology, 41, 521–528.
Source: NC State University Libraries
Added: August 6, 2018
Employment
Updated: November 12th, 2018 14:21
2018 - present
North Carolina State University Raleigh, NC, US
Assistant Professor
Forest Biotechnology Group
Education
Updated: October 24th, 2016 13:50
2007 - 2012
North Carolina State University Raleigh, NC, US
Ph.D.
Forestry and Environmental Resources
