Jack P. Wang is an Assistant Professor in the Forest Biotechnology Group, Department of Forestry and Environmental Resources, College of Natural Resources at North Carolina State University. Jack received his B.S. degree in Biology and Chemistry from Waikato University, New Zealand in 2006, and completed his Ph.D. at North Carolina State University in 2012, under the mentorship of Dr. Vincent Chiang and Dr. Ron Sederoff. Jack is a forestry scientist with research experience in molecular genetics and biotechnology, particularly the integrative genomic and genetic analysis of plant metabolism for tree growth, development, and defense against biotic and abiotic stresses. Some highlights of his recent research include an unprecedented quantitative systematic analysis of the response to genetic regulation in the model tree species (Populus trichocarpa), with important immediate implications for plant growth and adaptation, as well as biofuels and biomaterials (published in 2018 in Nature Communications); demonstrating that protein phosphorylation acts as an on/off switch for AldOMT, a central enzyme in monolignol biosynthesis (published in 2015 in PNAS); characterizing the hetero-tetrameric 4CL enzyme complex formation, regulation and numerical modeling (published in 2014 in Plant Cell); and establishing a proteomic-based predictive kinetic metabolic-flux (PKMF) model of the monolignol biosynthetic pathway (published in 2014 in Plant Cell). This PKMF model predicts how monolignol pathway enzymes affect lignin content and composition, explains a long-standing paradox regarding the regulation of monolignol subunit ratios in lignin, and reveals novel mechanisms involved in the regulation of lignin biosynthesis.
2024 journal article
Beyond Low Lignin: Identifying the Primary Barrier to Plant Biomass Conversion by Fermentative Bacteria
Science Advances.
2023 article
A COMPASS histone H3K4 trimethyltransferase pentamer transactivates drought tolerance and growth/biomass production in <i>Populus trichocarpa</i>
Zhang, B., Wang, Z., Dai, X., Gao, J., Zhao, J., Ma, R., … Li, W. (2023, December 14). NEW PHYTOLOGIST.
2023 article
Cell-type-specific PtrWOX4a and PtrVCS2 form a regulatory nexus with a histone modification system for stem cambium development in Populus trichocarpa
Dai, X., Zhai, R., Lin, J., Wang, Z., Meng, D., Li, M., … Li, W. (2023, January 9). NATURE PLANTS.
2023 journal article
Multiplex CRISPR editing of wood for sustainable fiber production
SCIENCE, 381(6654), 216-+.
2023 article
Woody plant cell walls: Fundamentals and utilization
Li, W., Lin, Y.-C. J., Chen, Y.-L., Zhou, C., Li, S., De Ridder, N., … Chiang, V. L. (2024, January 1). MOLECULAR PLANT, Vol. 17, pp. 112–140.
2022 journal article
<p>Plant biomass fermentation by the extreme thermophile Caldicellulosiruptor bescii for co-production of green hydrogen and acetone: Technoeconomic analysis</p>
BIORESOURCE TECHNOLOGY, 348.
2022 article
Dimerization of PtrMYB074 and PtrWRKY19 mediates transcriptional activation of PtrbHLH186 for secondary xylem development in Populus trichocarpa
Liu, H., Gao, J., Sun, J., Li, S., Zhang, B., Wang, Z., … Li, W. (2022, March 3). NEW PHYTOLOGIST, Vol. 5.
2022 journal article
Enhancing HR Frequency for Precise Genome Editing in Plants
FRONTIERS IN PLANT SCIENCE, 13.
2022 journal article
Fermentative conversion of unpretreated plant biomass: A thermophilic threshold for indigenous microbial growth
BIORESOURCE TECHNOLOGY, 367.
2021 article
CRISPR-Cas9 editing of CAFFEOYL SHIKIMATE ESTERASE 1 and 2 shows their importance and partial redundancy in lignification in Populus tremula x P. alba
Vries, L., Brouckaert, M., Chanoca, A., Kim, H., Regner, M. R., Timokhin, V. I., … Boerjan, W. (2021, August 6). PLANT BIOTECHNOLOGY JOURNAL, Vol. 11.
2021 journal article
Enzyme Complexes of Ptr4CL and PtrHCT Modulate Co-enzyme A Ligation of Hydroxycinnamic Acids for Monolignol Biosynthesis in Populus trichocarpa
FRONTIERS IN PLANT SCIENCE, 12.
2021 journal article
Thermophilic microbial deconstruction and conversion of natural and transgenic lignocellulose
Environmental Microbiology Reports, 13(3), 272–293.
2021 journal article
Transcriptional reprogramming of xylem cell wall biosynthesis in tension wood
PLANT PHYSIOLOGY, 186(1), 250–269.
2021 journal article
p A PtrLBD39-mediated transcriptional network regulates tension wood formation in Populus trichocarpa
PLANT COMMUNICATIONS, 3(1).
2020 journal article
A multiscale model of lignin biosynthesis for predicting bioenergy traits in Populus trichocarpa
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 19, 168–182.
2020 journal article
MYB Transcription Factor161 Mediates Feedback Regulation of Secondary wall-associated NAC-Domain1 Family Genes for Wood Formation
Plant Physiology, 9, pp.01033.2020.
2020 journal article
Modeling cross-regulatory influences on monolignol transcripts and proteins under single and combinatorial gene knockdowns in Populus trichocarpa
PLOS Computational Biology.
Ed(s): S. Roy
2020 journal article
Monolignol Benzoates Incorporate into the Lignin of Transgenic Populus trichocarpa Depleted in C3H and C4H
ACS Sustainable Chemistry and Engineering, 8(9), 3644–3654.
Contributors: H. Kim *, Q. Li *, S. Karlen *, R. Smith *, R. Shi n, J. Liu n, C. Yang n, S. Tunlaya-Anukit n
2020 review
Regulation of Lignin Biosynthesis by Post-translational Protein Modifications
[Review of ]. FRONTIERS IN PLANT SCIENCE, 11.
2020 journal article
Tracheid Associated Transcription Factors in Loblolly Pine.
Tree Physiology, 2.
2020 journal article
Use of the lignocellulose-degrading bacterium Caldicellulosiruptor bescii to assess recalcitrance and conversion of wild-type and transgenic poplar
BIOTECHNOLOGY FOR BIOFUELS, 13(1).
2019 journal article
A novel synthetic-genetic-array-based yeast one-hybrid system for high discovery rate and short processing time
GENOME RESEARCH, 29(8), 1343–1351.
2019 review
Enzyme-Enzyme Interactions in Monolignol Biosynthesis
[Review of ]. FRONTIERS IN PLANT SCIENCE, 9.
Contributors: , B. Liu *, Y. Sun *, V. Chiang n & R. Sederoff n n
2019 journal article
Hierarchical Transcription Factor and Chromatin Binding Network for Wood Formation in Populus trichocarpa
The Plant Cell, 31(3), 602–626.
2019 article
Modeling cross-regulatory influences on monolignol transcripts and proteins under single and combinatorial gene knockdowns in Populus trichocarpa
Matthews, M. L., Wang, J. P., Sederoff, R., Chiang, V. L., & Williams, C. M. (2019, June 19). (Vol. 6). Vol. 6.
2019 journal article
Quantitative fermentation of unpretreated transgenic poplar by Caldicellulosiruptor bescii
NATURE COMMUNICATIONS, 10(1).
Contributors: C. Straub n, P. Khatibi n, n , J. Conway n, A. Williams-Rhaesa *, I. Peszlen n , V. Chiang n, M. Adams *, R. Kelly n
2019 review
Systems and Synthetic Biology of Forest Trees: A Bioengineering Paradigm for Woody Biomass Feedstocks
[Review of ]. FRONTIERS IN PLANT SCIENCE, 10.
Contributors: A. Myburg *, S. Hussey *, n , N. Street * & E. Mizrachi *
2018 journal article
Assessing the impact of the 4CL enzyme complex on the robustness of monolignol biosynthesis using metabolic pathway analysis
PLOS ONE, 13(3), e0193896.
Contributors: P. Naik n, n , R. Sederoff n, V. Chiang n, C. Williams n & J. Ducoste n
Ed(s): D. Cullen
2018 journal article
CAD1 and CCR2 protein complex formation in monolignol biosynthesis in Populus trichocarpa
NEW PHYTOLOGIST, 222(1), 244–260.
2018 journal article
Flux modeling for monolignol biosynthesis
Current Opinion in Biotechnology, 56, 187–192.
Contributors: , M. Matthews n, P. Naik n, C. Williams n , J. Ducoste n , R. Sederoff n, V. Chiang n n
2018 journal article
Improving wood properties for wood utilization through multi-omics integration in lignin biosynthesis
Nature Communications, 9(1), 1579.
Contributors: , M. Matthews n, C. Williams n , R. Shi n, C. Yang n, S. Tunlaya-Anukit n, H. Chen n, Q. Li * n
2018 journal article
The AREB1 Transcription Factor Influences Histone Acetylation to Regulate Drought Responses and Tolerance in Populus trichocarpa
Plant Cell, 31(3), 663–686.
Contributors: S. Li *, Y. Lin n, P. Wang *, B. Zhang *, M. Li *, S. Chen *, R. Shi n, S. Tunlaya-Anukit n
2017 journal article
Reciprocal cross-regulation of VND and SND multigene TF families for wood formation in Populus trichocarpa
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114(45), E9722–E9729.
Contributors: Y. Lin n, H. Chen n, Q. Li *, W. Li n, n , R. Shi n, S. Tunlaya-Anukit n, P. Shuai n
2017 journal article
Tissue and cell-type co-expression networks of transcription factors and wood component genes in Populus trichocarpa
PLANTA, 245(5), 927–938.
2016 chapter
A Proteomic-Based Quantitative Analysis of the Relationship Between Monolignol Biosynthetic Protein Abundance and Lignin Content Using TransgenicPopulus trichocarpa
In V. C. Kumi Yoshida & S. Quideau (Eds.), Recent Advances in Polyphenol Research (Vol. 5, pp. 89–107).
Contributors: , S. Tunlaya-Anukit, R. Shi, T. Yeh, L. Chuang, F. Isik* , C. Yang, J. Liu *
Ed(s): V. Kumi Yoshida & S. Quideau
2016 journal article
A cell wall-bound anionic peroxidase, PtrPO21, is involved in lignin polymerization in Populus trichocarpa
Tree Genetics & Genomes, 12(2).
2015 journal article
4-Coumaroyl and Caffeoyl Shikimic Acids Inhibit 4-Coumaric Acid: Coenzyme A Ligases and Modulate Metabolic Flux for 3-Hydroxylation in Monolignol Biosynthesis of Populus trichocarpa
MOLECULAR PLANT, 8(1), 176–187.
2015 journal article
Comparative proteomic analysis of Populus trichocarpa early stem from primary to secondary growth
JOURNAL OF PROTEOMICS, 126, 94–108.
2015 journal article
Elucidation of Xylem-Specific Transcription Factors and Absolute Quantification of Enzymes Regulating Cellulose Biosynthesis in Populus trichocarpa
JOURNAL OF PROTEOME RESEARCH, 14(10), 4158–4168.
Contributors: P. Loziuk n, J. Parker n, W. Li n, C. Lin n, n , Q. Li *, R. Sederoff n, V. Chiang n, D. Muddiman n
2015 journal article
Phosphorylation is an on/off switch for 5-hydroxyconiferaldehyde O-methyltransferase activity in poplar monolignol biosynthesis
Proceedings of the National Academy of Sciences, 112(27), 8481–8486.
Contributors: , L. Chuang n, P. Loziuk n, H. Chen n, Y. Lin n, R. Shi n, G. Qu *, D. Muddiman n , R. Sederoff n, V. Chiang n n
2014 journal article
A simple improved-throughput xylem protoplast system for studying wood formation
NATURE PROTOCOLS, 9(9), 2194–2205.
2014 journal article
Complete Proteomic-Based Enzyme Reaction and Inhibition Kinetics Reveal How Monolignol Biosynthetic Enzyme Families Affect Metabolic Flux and Lignin in Populus trichocarpa
The Plant Cell, 26(3), 894–914.
Contributors: , P. Naik n, H. Chen n, R. Shi n, C. Lin n, J. Liu n, C. Shuford n, Q. Li n n
2014 review
Plant biotechnology for lignocellulosic biofuel production
[Review of ]. PLANT BIOTECHNOLOGY JOURNAL, 12(9), 1174–1192.
Contributors: Q. Li *, J. Song *, S. Peng *, n , G. Qu *, R. Sederoff n, V. Chiang n
2014 journal article
Systems Biology of Lignin Biosynthesis in Populus trichocarpa: Heteromeric 4-Coumaric Acid:Coenzyme A Ligase Protein Complex Formation, Regulation, and Numerical Modeling
The Plant Cell, 26(3), 876–893.
Contributors: H. Chen n, J. Song n, n , Y. Lin n, J. Ducoste n , C. Shuford n, J. Liu n, Q. Li n
2013 journal article
Monolignol Pathway 4-Coumaric Acid: Coenzyme A Ligases in Populus trichocarpa: Novel Specificity, Metabolic Regulation, and Simulation of Coenzyme A Ligation Fluxes
PLANT PHYSIOLOGY, 161(3), 1501–1516.
Contributors: H. Chen n, J. Song n, C. Williams n , C. Shuford n, J. Liu n, n , Q. Li n, R. Shi n
2013 journal article
Regulation of phenylalanine ammonia-lyase (PAL) gene family in wood forming tissue of Populus trichocarpa
Planta, 238(3), 487–497.
Contributors: R. Shi n, C. Shuford n, n , Y. Sun n, Z. Yang n, H. Chen n, S. Tunlaya-Anukit n, Q. Li n
2013 journal article
Understanding the Role of Proteolytic Digestion on Discovery and Targeted Proteomic Measurements Using Liquid Chromatography Tandem Mass Spectrometry and Design of Experiments
JOURNAL OF PROTEOME RESEARCH, 12(12), 5820–5829.
Contributors: P. Loziuk n, n , Q. Li n, R. Sederoff n, V. Chiang n & D. Muddiman n
2012 journal article
Comprehensive Quantification of Monolignol-Pathway Enzymes in Populus trichocarpa by Protein Cleavage Isotope Dilution Mass Spectrometry
Journal of Proteome Research, 11(6), 3390–3404.
Contributors: C. Shuford n, Q. Li n, Y. Sun n, H. Chen n, n , R. Shi n, R. Sederoff n, V. Chiang n, D. Muddiman n
2012 journal article
Functional redundancy of the two 5-hydroxylases in monolignol biosynthesis of Populus trichocarpa: LC-MS/MS based protein quantification and metabolic flux analysis
PLANTA, 236(3), 795–808.
Contributors: , C. Shuford n, Q. Li n, J. Song n, Y. Lin n, Y. Sun n, H. Chen n, C. Williams n n
2011 journal article
Down-regulation of glycosyltransferase 8D genes in Populus trichocarpa caused reduced mechanical strength and xylan content in wood
TREE PHYSIOLOGY, 31(2), 226–236.
Contributors: Q. Li n, D. Min n, J. Wang n, I. Peszlen n , L. Horvath n, B. Horvath n, Y. Nishimura n, H. Jameel n, H. Chang n, V. Chiang n
2007 journal article
A novel O-methyl transferase-like gene with a drastic ectopic expression in response to tension wood formation in Populus trichocarpa
Cellulose Chemistry and Technology, 41(9-10), 521–528. http://www.scopus.com/inward/record.url?eid=2-s2.0-60749092120&partnerID=MN8TOARS
2007 journal article
A novel O-methyl transferase-like gene with drastic ectopic expression in response to tension wood formation in Populus trichocarpa
Cellulose Chemistry and Technology, 41, 521–528.
Updated: November 12th, 2018 14:21
2018 - present
Updated: October 24th, 2016 13:50
2007 - 2012
Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.
Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.