Jing Qu

Works (1)

Updated: April 25th, 2025 17:34

2023 article

Structure and Dynamics of DNA and RNA Double Helices Formed by d(CTG), d(GTC), r(CUG), and r(GUC) Trinucleotide Repeats and Associated DNA–RNA Hybrids

Fakharzadeh, A., Qu, J., Pan, F., Sagui, C., & Roland, C. (2023, September 8). The Journal of Physical Chemistry B, Vol. 9.

By: A. Fakharzadeh n, J. Qu n, F. Pan*, C. Sagui n  & C. Roland n 

MeSH headings : Adult; Humans; Trinucleotide Repeats; Biophysics; DNA; Hydrogen Bonding; RNA
topics (OpenAlex): Genetic Neurodegenerative Diseases; RNA Research and Splicing; RNA and protein synthesis mechanisms
TL;DR: Molecular dynamics simulations of homoduplexes associated with myotonic dystrophy type 1 found that the U·U and T·T mismatches are dynamic, favoring anti-anti conformations inside the helical core, followed by anti-syn and syn-syn conformations. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: October 10, 2023

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