Jim E Riviere

Mechanisms of toxicity and residue considerations of rodenticide exposure in food Animals-a FARAD perspective

Mercer, M. A., Davis, J. L., Riviere, J. E., Baynes, R. E., Tell, L. A., Jaberi-Douraki, M., … Lin, Z. (2022, March 1). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION.

Predicting Nanoparticle Delivery to Tumors Using Machine Learning and Artificial Intelligence Approaches

INTERNATIONAL JOURNAL OF NANOMEDICINE.

Update on withdrawal intervals following extralabel use of procaine penicillin G in cattle and swine

Halleran, J. L., Papich, M. G., Li, M., Lin, Z., Davis, J. L., Maunsell, F. P., … Foster, D. M. (2022, January 1). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION.

Data-driven methodology for discovery and response to pulmonary symptomology in hypertension through AI and machine learning: Application to COVID-19 related pharmacovigilance

Development and Application of an interactive Physiologically Based Pharmacokinetic (iPBPK) Model to Predict Oxytetracycline Tissue Distribution and Withdrawal Intervals in Market-Age Sheep and Goats

Toxicological Sciences.

Percutaneous Absorption of Chemical Mixtures

In N. Dragićević (Ed.), Percutaneous Absorption (5th ed., pp. 305–314).

Pulmonary adverse drug event data in hypertension with implications on COVID-19 morbidity

SCIENTIFIC REPORTS.

A study to assess the correlation between plasma, oral fluid and urine concentrations of flunixin meglumine with the tissue residue depletion profile in finishing-age swine

BMC Veterinary Research, 16(1).

Development and application of an interactive physiological based pharmacokinetic (iPBPK) model interface to estimate withdrawal intervals for penicillin G in cattle and swine

The Toxicologist, 174(1), 458.

Meta-Analysis of Nanoparticle Delivery to Tumors Using a Physiologically Based Pharmacokinetic Modeling and Simulation Approach

ACS Nano, 14(3), 3075–3095.

Pharmacovigilance in patients with diabetes: A data-driven analysis identifying specific RAS antagonists with adverse pulmonary safety profiles that have implications for COVID-19 morbidity and mortality

Journal of the American Pharmacists Association, 60(6), e145–e152.

Physiological parameter values for physiologically based pharmacokinetic models in food-producing animals. Part 1: Cattle and Swine

The Toxicologist, 174(1), 461.

Physiological parameter values for physiologically based pharmacokinetic models in food-producing animals. Part I: Cattle and swine

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS.

Physiological parameter values for physiologically based pharmacokinetic models in food-producing animals. Part II: Chicken and turkey

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS.

Physiological parameter values for physiologically based pharmacokinetic models in food‐producing animals. Part III: Sheep and goat

Journal of Veterinary Pharmacology and Therapeutics, 44(4), 456–477.

Physiologically based pharmacokinetic modeling and simulation of nanoparticle delivery to tumors in mice

The Toxicologist, 174(1), 460.

An integrated experimental and physiologically based pharmacokinetic modeling study of penicillin G in heavy sows

Journal of Veterinary Pharmacology and Therapeutics, 42(4), 461–475.

Assessing delivery efficiency of nanoparticles to tumors in tumor-bearing mice using a physiologically based pharmacokinetic modeling and simulation approach

The Toxicologist, 168(1), 476–477,

Data Science

SCIENCE BREAKTHROUGHS TO ADVANCE FOOD AND AGRICULTURAL RESEARCH BY 2030, pp. 145–164.

Development and application of a population physiologically based pharmacokinetic model for florfenicol and its metabolite florfenicol amine in cattle

FOOD AND CHEMICAL TOXICOLOGY, 126, 285–294.

Extralabel drug use in wildlife and game animals

Journal of the American Veterinary Medical Association, 255(5), 555–568.

Integration of Food Animal Residue Avoidance Databank (FARAD) Empirical Methods for Drug Withdrawal Interval Determination with a Mechanistic Population-Based Interactive Physiologically Based Pharmacokinetic (iPBPK) Modeling Platform: Example for Flunixin Meglumine Administration

The Toxicologist, 168(1), 191.

Integration of Food Animal Residue Avoidance Databank (FARAD) empirical methods for drug withdrawal interval determination with a mechanistic population-based interactive physiologically based pharmacokinetic (iPBPK) modeling platform: example for flunixin meglumine administration

Archives of Toxicology, 93(7), 1865–1880.

Making Sense of Pharmacovigilance and Drug Adverse Event Reporting: Comparative Similarity Association Analysis Using AI Machine Learning Algorithms in Dogs and Cats

Topics in Companion Animal Medicine, 37, 100366.

Novel Data Sharing Agreement to Accelerate Big Data Translational Research Projects in the One Health Sphere

Topics in Companion Animal Medicine, 37, 100367.

A general physiologically-based pharmacokinetic model for gold nanoparticles of different sizes with multiple administration routes in rats

The Toxicologist, 162(1), 526.

Absorption, Distribution, Metabolism, and Elimination

In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 8–40). Ames, Iowa: Wiley-Blackwell.

Aminoglycoside Antibiotics

In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 877–902). Ames, Iowa: Wiley-Blackwell.

Antiarrhythmic Agents

In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 537–552). Ames, Iowa: Wiley-Blackwell.

Application of population physiologically-based pharmacokinetic model for penicillin G in dairy cows to facilitate food safety assessment

The Toxicologist, 162(1), 526.

Automation and applications of the tolerance limit method in estimating meat withdrawal periods for veterinary drugs

Computers and Electronics in Agriculture, 146, 125–135.

Chemical Residues in Tissues of Food Animals

In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 1469–1480). Ames, Iowa: Wiley-Blackwell.

Consequences of fipronil exposure in egg-laying hens

Journal of the American Veterinary Medical Association, 253(1), 57–60.

Dermatopharmacology: Drugs Acting Locally on the Skin

In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 1278–1301). Ames, Iowa: Wiley-Blackwell.

Dosage Forms and Veterinary Feed Directives

In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 1459–1464). Ames, Iowa: Wiley-Blackwell.

Editorial

Journal of Veterinary Pharmacology and Therapeutics, 41(3), 355–355.

Extralabel drug use in small ruminants

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 253(8), 1001–1009.

Impact of natural compounds on dermal absorption for consumer products and their computational prediction

The Toxicologist, 162(1), 179.

Mathematical modeling and simulation in animal health. Part III: Using nonlinear mixed-effects to characterize and quantify variability in drug pharmacokinetics

Journal of Veterinary Pharmacology and Therapeutics, 41(2), 171–183.

Modeling gold nanoparticle biodistribution after arterial infusion into perfused tissue: effects of surface coating, size and protein corona

Nanotoxicology, 12(10), 1093–1112.

Pharmacokinetics

In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 41–64). Ames, Iowa: Wiley-Blackwell.

Probabilistic Physiologically Based Pharmacokinetic Model for Penicillin G in Milk From Dairy Cows Following Intramammary or Intramuscular Administrations

Toxicological Sciences, 164(1), 85–100.

Probabilistic risk assessment of gold nanoparticles after intravenous administration by integrating in vitro and in vivo toxicity with physiologically based pharmacokinetic modeling

Nanotoxicology, 12(5), 453–469.

Probabilistic risk assessment of gold nanoparticles by integrating in vitro and in vivo toxicity with physiologically-based pharmacokinetic modeling

The Toxicologist, 162(1), 526.

Tetracycline Antibiotics

In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 858–876). Ames, Iowa: Wiley-Blackwell.

Variation in fluoroquinolone pharmacodynamic parameter values among isolates of two bacterial pathogens of bovine respiratory disease

Scientific Reports, 8(1).

Veterinary Pharmacology and Therapeutics

(10th ed.). Ames, Iowa: Wiley-Blackwell.

Veterinary Pharmacology: An Introduction to the Discipline

In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 3–7). Ames, Iowa: Wiley-Blackwell.

Avoiding violative flunixin meglumine residues in cattle and swine

Journal of the American Veterinary Medical Association, 250(2), 182–189.

Biocorona formation on gold nanoparticles modulates human proximal tubule kidney cell uptake, cytotoxicity and gene expression

Toxicology in Vitro, 42, 150–160.

Biological Surface Adsorption Index of Nanomaterials: Modelling Surface Interactions of Nanomaterials with Biomolecules

Advances in Experimental Medicine and Biology, 947, 207–253.

Considerations for extralabel drug use in calves

Journal of the American Veterinary Medical Association, 250(11), 1275–1282.

Dermatotoxicology: Computational approaches to predicting absorption of complex topical chemical mixtures

In S. Ekins (Ed.), Computational Toxicology (2nd ed., pp. 269–290). New York: John Wiley.

Development and application of a population physiologically based pharmacokinetic model for penicillin G in swine and cattle for food safety assessment

Food and Chemical Toxicology, 107, 74–87.

Guide to FARAD resources: historical and future perspectives

Journal of the American Veterinary Medical Association, 250(10), 1131–1139.

Modulation of topical chemical absorption by 14 natural compounds: a quantitative structure permeation (QSPR) analysis of components often found in topical preparations

Cutaneous and Ocular Toxicology, 36(3), 237–252.

Multi-Walled Carbon Nanotube Exposure Alters Protein Expression in Human Keratinocytes

In Nanomedicine in Cancer (pp. 461–485).

Nano in-vitro cellular uptake simulator (NICUS): a model to quantitate nanomaterial endocytosis kinetics and intracellular dose

The Toxicologist, 156, 303.

NanoEHS beyond toxicity – focusing on biocorona

Environmental Science: Nano, 4(7), 1433–1454.

Performance Assessment and Translation of Physiologically Based Pharmacokinetic Models From acslX to Berkeley Madonna, MATLAB, and R Language: Oxytetracycline and Gold Nanoparticles As Case Examples

Toxicological Sciences, 158(1), 23–35.

Pharmacokinetics of Mequindox and Its Marker Residue 1,4-Bisdesoxymequindox in Swine Following Multiple Oral Gavage and Intramuscular Administration: An Experimental Study Coupled with Population Physiologically Based Pharmacokinetic Modeling

Journal of Agricultural and Food Chemistry, 65(28), 5768–5777.

Surface chemistry of gold nanoparticles determines the biocorona composition impacting cellular uptake, toxicity and gene expression profiles in human endothelial cells

Nanotoxicology, 11(4), 507–519.

Zinc Oxide Nanoparticle–Poly I:C RNA Complexes: Implication as Therapeutics against Experimental Melanoma

Molecular Pharmaceutics, 14(3), 614–625.

A computational framework for interspecies pharmacokinetics, exposure and toxicity assessment of gold nanoparticles

Nanomedicine, 11(2), 107–119.

A new voyage begins: welcoming new editors and the launching of Pharmacokinetic Reports

Journal of Veterinary Pharmacology and Therapeutics, 39, 317.

A physiological based pharmacokinetic model for polyethylene glycol-coated gold nanoparticles of different sizes in adult mice

Nanotoxicology, 10, 162–172.

Assessment of penetrant and vehicle mixture properties on transdermal permeability using a mixed effect pharmacokinetic model of ex vivo porcine skin

Biopharmaceutics & Drug Disposition, 37(7), 387–396.

Biological and environmental surface interactions of nanomaterials: characterization, modeling, and prediction

Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 9(3), e1440.

Biological surface adsorption index: environmental applications and parallel molecular dynamics simulations

Proceedings of 8th International Nanotoxicology Conference, 72.

Caveats to making in vitro to in vivo and interspecies extrapolations of nanoparticle biological interactions using in silico computational modeling

The 51st Midwest Regional Meeting of the American Chemical Society, 47.

Estimation of tulathromycin depletion in plasma and milk after subcutaneous injection in lactating dairy goats using a nonlinear mixed-effect pharmacokinetic modeling approach

BMC Veterinary Research, 12(258).

Exploring Post-Treatment Reversion of Antimicrobial Resistance in Enteric Bacteria of Food Animals as a Resistance Mitigation Strategy

Foodborne Pathogens and Disease, 13(11), 610–617.

Health concerns and management of select veterinary drug residues

Food and Chemical Toxicology, 88, 112–122.

Human food safety implications of variation in food animal drug metabolism

Scientific Reports, 6(27907).

Influence of some plant extracts on the transdermal absorption and penetration of marker residues

Cutaneous and Ocular Toxicology, 30, 1–7.

Limitation of MIC as sole metric of pharmacodynamic response across the range of antimicrobial susceptibility within a single bacterial species

Scientific Reports, 6(37907).

Mathematical modeling and simulation in animal health – Part II : principles, methods, applications, and value of physiologically based pharmacokinetic modeling in veterinary medicine and food safety assessment

Journal of Veterinary Pharmacology and Therapeutics, 39(5), 421–438.

Mathematical modeling and simulation in animal health. Part I: Moving beyond pharmacokinetics

Journal of Veterinary Pharmacology and Therapeutics, 39(3), 213–223.

Mechanistic Toxicity Assessment of Hexahydroisohumulone in Canine Hepatocytes, Renal Proximal Tubules, Bone Marrow-Derived Mesenchymal Stem Cells, and Enterocyte-like Cells

International Journal of Veterinary Health Science & Research, 4(2), 88–103.

Mechanistic toxicity assessment of hexahydroisohumulone in canine hepatocytes, renal proximal tubules, and enterocyte like-cells

The Toxicologist, 150, 487.

Modulation of Chemical Dermal Absorption by 14 Natural Products: A Quantitative Structure Permeation (QSPR) Analysis of Components Often Found in Topical Cosmeceuticals

Cutaneous and Ocular Toxicology, 36(3), 237–252.

Observations on macrolide resistance in field isolates collected from bovine respiratory disease cases

Veterinary Microbiology, 192, 186–193.

Oxidative stress response in canine in vitro liver, kidney and intestinal models with seven potential dietary ingredients

Toxicology Letters, 241, 49–59.

Pharmacokinetics and tissue elimination of flunixin in veal calves

American Journal of Veterinary Research, 77(6), 634–640.

Physiological based pharmacokinetic (PBPK) modeling of nanomaterials: Why is quantitation and anatomical / physiological reality so important?

Proceedings of 8th International Nanotoxicology Conference, 385.

Potential mechanism of toxicity of hexahydroisohumulone in an in vitro canine model

Presented at the WINNS 2016 – Growing Science in Pet Nutrition.

Predicting and modeling in vivo nanoparticle biodistribution: caveats to making in vitro and rodent interspecies extrapolations

11th International Particle Toxicology Conference, 54.

Protein corona modulation of hepatocyte uptake and molecular mechanisms of gold nanoparticle toxicity

Nanotoxicology, 11(1), 64–75.

Protocol for diversion of confirmed positive bulk raw milk tankers to calf ranches – A review of the Pharmacokinetics of tetracyclines and sulfonamides in veal calves

Animal Health Research Reviews, 17(2), 127–136.

Quantification of nanoparticle pesticide adsorption: computational approaches based on experimental data

Nanotoxicology, 10(8), 1118–1128.

Residue concerns following exposure to livestock to oil and petroleum products

Journal of the American Veterinary Medical Association, 248, 145–146.

Screening and Confirmatory Analyses of Flunixin in Tissues and Bodily Fluids after Intravenous or Intramuscular Administration to Cull Dairy Cows with or without Lipopolysaccharide Challenge

Journal of Agricultural and Food Chemistry, 64(1), 336–345.

The effects of vehicle mixtures on transdermal absorption: thermodynamics, mechanism, assessment and prediction

In N. Dragicevic-Curic & H. I. Maibach (Eds.), Percutaneous Penetration Enhancers Drug Penetration Into/Through the Skin: Methodology and General Considerations (pp. 95–118). New York: Springer.

Toxicological effects of pet food ingredients on canine bone marrow-derived mesenchymal stem cells and enterocyte-like cells

Journal of Applied Toxicology, 36(2), 189–198.

A Framework for Meta-Analysis of Veterinary Drug Pharmacokinetic Data Using Mixed Effect Modeling

Journal of Pharmaceutical Sciences, 104(4), 1230–1239.

Canine renal proximal tubule cells as an in vitro model for toxicity assessment of pet food ingredients

The Toxicologist, 144, 490.

Comparative In Vitro Cytotoxicity of 20 Potential Food Ingredients in Canine Liver, Kidney, Bone Marrow-Derived Mesenchymal Stem Cells, and Enterocyte-like Cells

Applied In Vitro Toxicology, 1(4), 276–288.

Comparison of pharmacokinetics and milk elimination of flunixin in healthy cows and cows with mastitis

Journal of the American Veterinary Medical Association, 246(1), 118–125.

Determination of thermodynamic solubility of active pharmaceutical ingredients for veterinary species: a new USP general chapter

Pharmacopeial Forum, 41(3).

Development and Application of a Multiroute Physiologically Based Pharmacokinetic Model for Oxytetracycline in Dogs and Humans

Journal of Pharmaceutical Sciences, 104(1), 233–243.

Development of a physiologically-relevant multivariate nanoparticle molecular interaction fingerprint

Presented at the 250th American Chemical Society National Meeting, Boston, MA.

Differential effects of some natural compounds on the transdermal absorption and penetration of caffeine and salicylic acid

International Journal of Pharmaceutics, 483(1-2), 151–157.

Egg residue considerations during the treatment of backyard poultry

Journal of the American Veterinary Medical Association, 247(12), 1388–1395.

Estimation of residue depletion of cyadox and its marker residue in edible tissues of pigs using physiologically based pharmacokinetic modeling

Food Additives & Contaminants: Part A, 32(12), 2002–2017.

Excretory, Secretory, and Tissue Residues after Label and Extra-label Administration of Flunixin Meglumine to Saline- or Lipopolysaccharide-Exposed Dairy Cows

Journal of Agricultural and Food Chemistry, 63(19), 4893–4901.

Flunixin urine residues in culled dairy cows and its relevance to food safety and environmental concern

Presented at the 250th American Chemical Society National Meeting, Boston, MA.

Gold and silver nanoparticle interactions with human proteins: impact and implications in biocorona formation

Journal of Materials Chemistry B, 3(10), 2075–2082.

In vitro safety assessment of food ingredients in canine renal proximal tubule cells

Toxicology in Vitro, 29(2), 289–298.

Interaction of silver and gold nanoparticles with protein biocorona formation and its impact on cellular toxicity

International Journal of Toxicology, 34, 78–79.

Nanoparticle surface characterization and clustering through concentration-dependent surface adsorption modeling

The Toxicologist, 144, 66.

Pharmacokinetics and pharmacodynamics of gamithromycin in pulmonary epithelial lining fluid in naturally occurring bovine respiratory disease in multisource commingled feedlot cattle

Journal of Veterinary Pharmacology and Therapeutics, 39(2), 157–166.

Pharmacokinetics of metallic nanoparticles

WIREs Nanomedicine and Nanobiotechnology, 7(2), 189–217.

Predicting Adsorption Affinities of Small Molecules on Carbon Nanotubes Using Molecular Dynamics Simulation

ACS Nano, 9(12), 11761–11774.

Predicting the impact of biocorona formation kinetics on interspecies extrapolations of nanoparticle biodistribution modeling

Nanomedicine, 10(1), 25–33.

Prediction and comparison of size-dependent biodistribution of polyethylene glycol-coated gold nanoparticles in adult mice: a physiologically based pharmacokinetic model

The Toxicologist, 144, 65.

Quantification of vehicle mixture effects on in vitro transdermal chemical flux using a random process diffusion model

Journal of Controlled Release, 217, 74–81.

Safety assessment of pet food ingredients using cryopreserved canine hepatocytes-based in vitro assays

The Toxicologist, 144, 20.

Safety assessment of potential food ingredients in canine hepatocytes

Food and Chemical Toxicology, 78, 105–115.

Toxicokinetic approaches to improving accuracy of drug withdrawal times in food producing animals to avoid toxic violative tissue residues

International Journal of Toxicology, 34, 78.

Antimicrobial Agents in Veterinary Medicine

Journal of Veterinary Pharmacology and Therapeutics, 37(1), 1–1.

Dermal Exposure and Absorption of Chemicals and Nanomaterials

In Reference Module in Biomedical Sciences.

Development of a physiologically based pharmacokinetic model for flunixin in cattle (Bos taurus)

Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment, 31(9), 1506–1521.

In silico models to predict dermal absorption from complex agrochemical formulations

SAR and QSAR in Environmental Research, 25(7), 565–588.

In silico models to predict dermal absorption from complex agrochemical formulations

SAR and QSAR in Environmental Research, 6, 1–24.

Interspecies Mixed-Effect Pharmacokinetic Modeling of Penicillin G in Cattle and Swine

Antimicrobial Agents and Chemotherapy, 58(8), 4495–4503.

Interspecies allometric meta-analysis of the comparative pharmacokinetics of 85 drugs across veterinary and laboratory animal species

Journal of Veterinary Pharmacology and Therapeutics, 38(3), 214–226.

Nanoparticle Surface Characterization and Clustering through Concentration-Dependent Surface Adsorption Modeling

ACS Nano, 8(9), 9446–9456.

Pharmacokinetics, tissue distribution, and excretion of nomegestrol acetate in female rats

European Journal of Drug Metabolism and Pharmacokinetics, 40(4), 435–442.

Prediction of formulation effects on dermal absorption of topically applied ectoparasiticides dosed in vitro on canine and porcine skin using a mixture-adjusted quantitative structure permeability relationship

Journal of Veterinary Pharmacology and Therapeutics, 37(5), 435–444.

The application of allometric scaling principles to predict pharmacokinetic parameters across species

Expert Opinion on Drug Metabolism & Toxicology, 10(9), 1241–1253.

development of a mixed-effect pharmacokinetic model for vehicle modulated in vitro transdermal flux of topically applied penetrants

Journal of Pharmaceutical Sciences, 103(3), 1002–1012.

Assessing vehicle effects on skin absorption of non-volatile compounds using membrane-coated fiber arrays

Cutaneous and Ocular Toxicology, 32(4), 283–289.

Assessing vehicle effects on skin absorption using artificial membrane assays

European Journal of Pharmaceutical Sciences, 50(5), 569–576.

Comparison of ELISA and LC-MS/MS for the measurement of Flunixin plasma concentrations in beef cattle after intravenous and subcutaneous administration

Journal of Agricultural and Food Chemistry, 61(11), 2679–2686.

Limitations of MIC as the sole criterion in antimicrobial drug dosage regimen design: The need for full characterization of antimicrobial pharmacodynamic profile especially for drug-resistant organisms

The Veterinary Journal, 198(1), 15–18.

Modeling the effect of experimental variables on the in vitro permeation of six model compounds across porcine skin

International Journal of Pharmaceutics, 443(1-2), 58–67.

Occurrence of flunixin residues in bovine milk samples from the USA

Food Additives & Contaminants: Part A, 30(9), 1513–1516.

Of mice, men and nanoparticle biocoronas: are in vitro to in vivo correlations and interspecies extrapolations realistic?

Nanomedicine, 8(9), 1357–1359.

Oxidative stress and dermal toxicity of iron oxide nanoparticles in vitro

Cell Biochemistry and Biophysics, 67(2), 461–476.

Predicting skin permeability from complex vehicles

[Review of ]. Advanced Drug Delivery Reviews, 65(2), 265–277.

Prediction of flunixin tissue residue concentrations in livers from diseased cattle

Food and Chemical Toxicology, 62, 876–879.

Protein binding modulates the cellular uptake of silver nanoparticles into human cells: Implications for in vitro to in vivo extrapolations?

Toxicology Letters, 220(3), 286–293.

Use of population pharmacokinetic modeling and Monte Carlo simulation to capture individual animal variability in the prediction of flunixin withdrawal times in cattle

Journal of Veterinary Pharmacology and Therapeutics, 36(3), 248–257.

Vasomodulation Influences on the Transdermal Delivery of Ibuprofen

Journal of Pharmaceutical Sciences, 102(11), 4072–4078.

Acute vascular effects of nanoparticle infusion in isolated perfused skin

Nanomedicine: Nanotechnology, Biology and Medicine, 8(4), 428–431.

Challenges obtaining a biowaiver for topical veterinary dosage forms

Journal of Veterinary Pharmacology and Therapeutics, 35, 103–114.

Development of a physiologically based pharmacokinetic model to predict tulathromycin distribution in goats

Journal of Veterinary Pharmacology and Therapeutics, 35(2), 121–131.

Evaluation of factors important in modeling plasma concentrations of tetracycline hydrochloride administered in water in swine

American Journal of Veterinary Research, 73(10), 1641–1649.

Experimental factors affecting in vitro absorption of six model compounds across porcine skin

Toxicology in Vitro, 26(7), 1191–1198.

In vitro biodistribution of silver nanoparticles in isolated perfused porcine skin flaps

Journal of Applied Toxicology, 32(11), 913–919.

Lack of hydroxylated fullerene toxicity after intravenous administration to female Sprague-Dawley rats

Journal of Toxicology and Environmental Health. Part A, 75(7), 367–373.

Pharmacokinetics and tissue elimination of tulathromycin following subcutaneous administration in meat goats

American Journal of Veterinary Research, 73(10), 1634–1640.

Plasma pharmacokinetics and milk residues of flunixin and 5-hydroxy flunixin following different routes of administration in dairy cattle

Journal of Dairy Science, 95(12), 7151–7157.

Quantum dot penetration into viable human skin

Nanotoxicology, 6(2), 173–185.

The effect of formulations and experimental conditions on in vitro human skin permeation—Data from updated EDETOX database

International Journal of Pharmaceutics, 434(1-2), 280–291.

Tulathromycin assay validation and tissue residues after single and multiple subcutaneous injections in domestic goats (Capra aegagrus hircus)

Journal of Veterinary Pharmacology and Therapeutics, 35(2), 113–120.

Comparative pharmacokinetics principles, techniques, and applications

In vitro toxicity assessment of three hydroxylated fullerenes in human skin cells

Toxicology in Vitro, 25(8), 2105–2112.

Mapping the surface adsorption forces of nanomaterials in biological systems

ACS Nano, 5(11), 9074–9081.

Pet food safety: a shared concern

British Journal of Nutrition, 106, S78–84.

Pharmacokinetics of tulathromycin after single and multiple subcutaneous injections in domestic goats (Capra aegagrus hircus)

Journal of Veterinary Pharmacology and Therapeutics, 34(5), 448–454.

Pharmacokinetics of tulathromycin following subcutaneous administration in meat goats

Research in Veterinary Science, 90(3), 477–479.

Predicting skin permeability from complex chemical mixtures: Dependency of quantitative structure permeation relationships on biology of skin model used

Toxicological Sciences, 119(1), 224–232.

Safety evaluation of sunscreen formulations containing titanium dioxide and zinc oxide nanoparticles in UVB sunburned skin: An in vitro and in vivo study

Toxicological Sciences, 123(1), 264–280.

A time to change: update on methods and manuscript topics appropriate for the journal of veterinary pharmacology and therapeutics

Journal of Veterinary Pharmacology and Therapeutics, 33(5), 415–415.

An index for characterization of nanomaterials in biological systems

Nature Nanotechnology, 5(9), 671–675.

Disposition of melamine residues in blood and milk from dairy goats exposed to an oral bolus of melamine

Food and Chemical Toxicology, 48(8-9), 2542–2546.

Evaluation of perfused porcine skin as a model system to quantitate tissue distribution of fullerene nanoparticles

Toxicology Letters, 197(1), 1–6.

Intrinsic biological property of colloidal fullerene nanoparticles (nC(60)): Lack of lethality after high dose exposure to human epidermal and bacterial cells

Toxicology Letters, 197(2), 128–134.

Modelling the effect of mixture components on permeation through skin

International Journal of Pharmaceutics, 398(1-2), 28–32.

New Technologies for Application to Veterinary Medicine

In F. Cunningham, J. Elliott, & P. Lees (Eds.), Comparative and Veterinary Pharmacology (pp. 191–210).

Riviere and Brooks pig skin flow-through [data file]

Skin penetration and kinetics of pristine fullerenes (C-60) topically exposed in industrial organic solvents

Toxicology and Applied Pharmacology, 242(1), 29–37.

Surfactant effects on skin absorption of model organic chemicals: Implications for dermal risk assessment studies

Journal of Toxicology and Environmental Health. Part A, 73(11), 725–737.

Validated models for predicting skin penetration from different vehicles

European Journal of Pharmaceutical Sciences, 41(5), 612–616.