Jim E. Riviere
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Works (1099)
Updated: November 23rd, 2023 05:01
2023 journal article
An artificial intelligence-assisted physiologically-based pharmacokinetic model to predict nanoparticle delivery to tumors in mice
JOURNAL OF CONTROLLED RELEASE, 361, 53–63.
co-author countries:
United States of America 🇺🇸
author keywords: Artificial intelligence; Machine learning; Physiologically based pharmacokinetic; modeling; Nanomedicine; Drug delivery; Nanotechnology
doi.org (publisher)
Sources: Web Of Science, ORCID
Added: August 7, 2023
2023 journal article
Development and application of an interactive generic physiologically based pharmacokinetic (igPBPK) model for adult beef cattle and lactating dairy cows to estimate tissue distribution and edible tissue and milk withdrawal intervals for per- and polyfluoroalkyl substances (PFAS)
FOOD AND CHEMICAL TOXICOLOGY, 181.
co-author countries:
United States of America 🇺🇸
author keywords: Per-and polyfluoroalkyl substances (PFAS); Chemical residue; Interactive generic physiologically based pharmacokinetic (igPBPK) modeling; Withdrawal interval; Food safety; Risk assessment
Source: Web Of Science
Added: November 20, 2023
2023 journal article
Development of machine learning algorithms to estimate maximum residue limits for veterinary medicines
FOOD AND CHEMICAL TOXICOLOGY, 179.
co-author countries:
United States of America 🇺🇸
author keywords: Unestablished MRL; Veterinary drugs; Machine learning; International market and trade; Published commodity (animal organ); Data resampling techniques
Source: Web Of Science
Added: September 25, 2023
2023 journal article
Meta-Analysis of Nanoparticle Distribution in Tumors and Major Organs in Tumor-Bearing Mice
ACS NANO, 17(20), 19810–19831.
co-author countries:
United States of America 🇺🇸
author keywords: Nanoparticle; Tumor delivery; Tissue distribution; Cancer; Nanomedicine
Sources: Web Of Science, ORCID
Added: October 10, 2023
2022 journal article
A web-based interactive physiologically based pharmacokinetic (iPBPK) model for meloxicam in broiler chickens and laying hens
FOOD AND CHEMICAL TOXICOLOGY, 168.
co-author countries:
United States of America 🇺🇸
author keywords: Meloxicam; Food Animal Residue Avoidance Databank (FARAD); Physiologically based pharmacokinetic (PBPK) modeling; Broiler chicken; Laying hen; Food safety
MeSH headings : Animal Feed; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chickens; Eggs; Female; Internet; Meloxicam
Source: Web Of Science
Added: December 12, 2022
2022 article
An Interactive Generic Physiologically Based Pharmacokinetic (igPBPK) Modeling Platform to Predict Drug Withdrawal Intervals in Cattle and Swine: A Case Study on Flunixin, Florfenicol, and Penicillin G
Chou, W.-C., Tell, L. A., Baynes, R. E., Davis, J. L., Maunsell, F. P., Riviere, J. E., & Lin, Z. (2022, June 1). TOXICOLOGICAL SCIENCES.
co-author countries:
United States of America 🇺🇸
author keywords: drug residue; Food Animal Residue Avoidance Databank (FARAD); food safety; interactive generic physiologically based pharmacokinetic (igPBPK) model; withdrawal interval (WDI)
MeSH headings : Animals; Cattle; Clonixin / analogs & derivatives; Drug Residues / analysis; Drugs, Generic; Models, Biological; Penicillin G / pharmacokinetics; Swine; Thiamphenicol / analogs & derivatives
Source: Web Of Science
Added: June 20, 2022
2022 article
Mechanisms of toxicity and residue considerations of rodenticide exposure in food Animals-a FARAD perspective
Mercer, M. A., Davis, J. L., Riviere, J. E., Baynes, R. E., Tell, L. A., Jaberi-Douraki, M., … Lin, Z. (2022, March 1). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 260, pp. 514–523.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Drug Residues; Rodenticides / toxicity
Source: Web Of Science
Added: March 28, 2022
2022 journal article
Predicting Nanoparticle Delivery to Tumors Using Machine Learning and Artificial Intelligence Approaches
INTERNATIONAL JOURNAL OF NANOMEDICINE, 17, 1365–1379.
Contributors: Z. Lin, W. Chou, Y. Cheng, C. He, N. Monteiro-Riviere* & *
author keywords: artificial intelligence; machine learning; physiologically based pharmacokinetic modeling; nanomedicine; drug delivery; nanotechnology
MeSH headings : Artificial Intelligence; Humans; Machine Learning; Nanoparticles; Neoplasms / drug therapy; Neural Networks, Computer
Sources: Web Of Science, ORCID
Added: March 30, 2022
2022 review
Toxicokinetics, dose-response, and risk assessment of nanomaterials: Methodology, challenges, and future perspectives
[Review of ]. WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY, 14(6).
co-author countries:
United States of America 🇺🇸
author keywords: dose-response assessment; nanomaterials; nanoparticles; risk assessment; toxicokinetics
MeSH headings : Animals; Humans; Toxicokinetics; Risk Assessment; Nanostructures / toxicity; Nanomedicine; Tissue Distribution
Source: Web Of Science
Added: December 19, 2022
2022 journal article
Update on withdrawal intervals following extralabel use of procaine penicillin G in cattle and swine
Journal of the American Veterinary Medical Association, 260(1), 50–55.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Cattle; Drug Residues; Penicillin G Procaine / therapeutic use; Swine
Sources: Web Of Science, ORCID
Added: February 7, 2022
2021 content posted
Data-driven methodology for discovery and response to pulmonary symptomology in hypertension through AI and machine learning: Application to COVID-19 related pharmacovigilance
co-author countries:
Sri Lanka 🇱🇰 United States of America 🇺🇸
Source: Crossref
Added: August 12, 2021
2021 journal article
Development and Application of an interactive Physiologically Based Pharmacokinetic (iPBPK) Model to Predict Oxytetracycline Tissue Distribution and Withdrawal Intervals in Market-Age Sheep and Goats
Toxicological Sciences, 183(2), 253–268.
co-author countries:
United States of America 🇺🇸
author keywords: drug residue; Food Animal Residue Avoidance Databank (FARAD); food safety; interactive physiologically based pharmacokinetic (iPBPK) model; oxytetracycline; withdrawal interval (WDI)
MeSH headings : Animals; Anti-Bacterial Agents; Drug Residues / analysis; Goats; Models, Biological; Oxytetracycline; Sheep; Tissue Distribution
Sources: Crossref, Web Of Science
Added: August 12, 2021
2021 journal article
Honey bee medicine for veterinarians and guidance for avoiding violative chemical residues in honey
Journal of the American Veterinary Medical Association, 259(8), 860–873.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Bees; Honey; Humans; Veterinarians
Source: NC State University Libraries
Added: May 21, 2022
2021 chapter
Percutaneous Absorption of Chemical Mixtures
In N. Dragićević (Ed.), Percutaneous Absorption (5th ed., pp. 305–314).
Ed(s): N. Dragićević
Source: Crossref
Added: August 12, 2021
2021 review
Physiological parameter values for physiologically based pharmacokinetic models in food-producing animals. Part II: Chicken and turkey
[Review of ]. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 44(4), 423–455.
co-author countries:
United States of America 🇺🇸
author keywords: blood flow; Food Animal Residue Avoidance Databank (FARAD); food safety; organ weight; physiologically based pharmacokinetic (PBPK) model
Source: Web Of Science
Added: December 21, 2020
2021 journal article
Pulmonary adverse drug event data in hypertension with implications on COVID-19 morbidity
SCIENTIFIC REPORTS, 11(1).
co-author countries:
Sri Lanka 🇱🇰 United States of America 🇺🇸
MeSH headings : Angiotensin Receptor Antagonists / adverse effects; Angiotensin-Converting Enzyme Inhibitors / adverse effects; Antihypertensive Agents / adverse effects; COVID-19 / epidemiology; Comorbidity; Hospital Mortality; Humans; Hypertension / drug therapy; Hypertension / epidemiology; Indoles / adverse effects; Quinapril / adverse effects; Retrospective Studies; COVID-19 Drug Treatment
Source: Web Of Science
Added: July 26, 2021
2020 journal article
A study to assess the correlation between plasma, oral fluid and urine concentrations of flunixin meglumine with the tissue residue depletion profile in finishing-age swine
BMC Veterinary Research, 16(1).
co-author countries:
Netherlands 🇳🇱 United States of America 🇺🇸
author keywords: Flunixin meglumine; Food safety; Pharmacokinetics; Physiologically based pharmacokinetic (PBPK) model; Swine; Tissue residue
MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / blood; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Anti-Inflammatory Agents, Non-Steroidal / urine; Clonixin / analogs & derivatives; Clonixin / blood; Clonixin / pharmacokinetics; Clonixin / urine; Food Contamination / analysis; Pork Meat / analysis; Saliva / chemistry; Sus scrofa / physiology
Source: Crossref
Added: August 13, 2021
2020 conference paper
Development and application of an interactive physiological based pharmacokinetic (iPBPK) model interface to estimate withdrawal intervals for penicillin G in cattle and swine
The Toxicologist, 174(1), 458.
Event: 59th Society of Toxicology annual meeting & ToxExpo at Anaheim, California on March 15-19, 2020
Source: NC State University Libraries
Added: August 13, 2021
2020 journal article
Meta-Analysis of Nanoparticle Delivery to Tumors Using a Physiologically Based Pharmacokinetic Modeling and Simulation Approach
ACS Nano, 14(3), 3075–3095.
co-author countries:
United States of America 🇺🇸
Contributors: Y. Cheng *, C. He *, *, N. Monteiro-Riviere* & Z. Lin *
author keywords: advanced material; drug delivery; nanomedicine; nanoparticle; physiologically based pharmacokinetic modeling; tissue biothstribution; tumor delivery
MeSH headings : Animals; Disease Models, Animal; Drug Carriers / chemistry; Drug Delivery Systems; Gold / administration & dosage; Gold / chemistry; Gold / pharmacokinetics; Injections, Intravenous; Male; Metal Nanoparticles / administration & dosage; Metal Nanoparticles / chemistry; Mice; Mice, Inbred BALB C; Neoplasms / chemistry; Neoplasms / metabolism; Tissue Distribution
Sources: Crossref, ORCID
Added: March 5, 2020
2020 journal article
Pharmacovigilance in patients with diabetes: A data-driven analysis identifying specific RAS antagonists with adverse pulmonary safety profiles that have implications for COVID-19 morbidity and mortality
Journal of the American Pharmacists Association, 60(6), e145–e152.
MeSH headings : Angiotensin Receptor Antagonists / adverse effects; Angiotensin Receptor Antagonists / therapeutic use; Angiotensin-Converting Enzyme 2 / metabolism; Angiotensin-Converting Enzyme Inhibitors / adverse effects; Angiotensin-Converting Enzyme Inhibitors / therapeutic use; COVID-19 / complications; COVID-19 / metabolism; COVID-19 / mortality; China / epidemiology; Diabetes Mellitus / drug therapy; Diabetes Mellitus / metabolism; Diabetic Nephropathies / complications; Diabetic Nephropathies / metabolism; Diabetic Nephropathies / prevention & control; Humans; Morbidity / trends; Pharmacovigilance; Prevalence; Renin-Angiotensin System / drug effects; Respiratory System / drug effects; Respiratory System / metabolism; SARS-CoV-2
Source: Crossref
Added: August 12, 2021
2020 journal article
Physiological parameter values for physiologically based pharmacokinetic models in food-producing animals. Part 1: Cattle and Swine
The Toxicologist, 174(1), 461.
Event: 59th Society of Toxicology annual meeting & ToxExpo at Anaheim, California on March 15-19, 2020
Source: NC State University Libraries
Added: August 13, 2021
2020 review
Physiological parameter values for physiologically based pharmacokinetic models in food-producing animals. Part I: Cattle and swine
[Review of ]. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 43(5), 385–420.
co-author countries:
United States of America 🇺🇸
author keywords: blood flow; food safety; organ weight; physiologically based pharmacokinetic model; withdrawal interval
MeSH headings : Animals; Cattle / physiology; Drug Residues; Models, Biological; Pharmaceutical Preparations / metabolism; Pharmacokinetics; Swine / physiology
Source: Web Of Science
Added: August 31, 2020
2020 journal article
Physiological parameter values for physiologically based pharmacokinetic models in food‐producing animals. Part III: Sheep and goat
Journal of Veterinary Pharmacology and Therapeutics, 44(4), 456–477.
co-author countries:
United States of America 🇺🇸
author keywords: blood flow; food animal residue avoidance databank; food safety; organ weight; physiologically based pharmacokinetic model
MeSH headings : Animals; Cattle; Chickens; Goats; Models, Biological; Organ Size; Sheep; Swine
Source: Crossref
Added: August 13, 2021
2020 conference paper
Physiologically based pharmacokinetic modeling and simulation of nanoparticle delivery to tumors in mice
The Toxicologist, 174(1), 460.
Event: 59th Society of Toxicology annual meeting & ToxExpo at Anaheim, California on March 15-19, 2020
Source: NC State University Libraries
Added: August 13, 2021
2019 journal article
An integrated experimental and physiologically based pharmacokinetic modeling study of penicillin G in heavy sows
Journal of Veterinary Pharmacology and Therapeutics, 42(4), 461–475.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: extralabel withdrawal interval; food safety; heavy sow; physiologically based pharmacokinetic (PBPK) model; procaine penicillin G (PPG); tissue residue
MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / pharmacokinetics; Body Weight; Computer Simulation; Dose-Response Relationship, Drug; Drug Residues; Female; Models, Biological; Penicillin G / administration & dosage; Penicillin G / pharmacokinetics; Swine / blood; Swine / metabolism; Swine / urine
Source: Crossref
Added: August 13, 2021
2019 conference paper
Assessing delivery efficiency of nanoparticles to tumors in tumor-bearing mice using a physiologically based pharmacokinetic modeling and simulation approach
The Toxicologist, 168(1), 476–477,
Event: 58th Society of Toxicology annual meeting & ToxExpo at Baltimore, Maryland on March 10-14, 2019
Source: NC State University Libraries
Added: August 13, 2021
2019 journal article
Development and application of a population physiologically based pharmacokinetic model for florfenicol and its metabolite florfenicol amine in cattle
FOOD AND CHEMICAL TOXICOLOGY, 126, 285–294.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: Physiologically based pharmacokinetic (PBPK) model; Withdrawal interval; Florfenicol; Florfenicol amine; Cattle
MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / analysis; Anti-Bacterial Agents / metabolism; Anti-Bacterial Agents / pharmacokinetics; Cattle; Cattle Diseases / drug therapy; China; Chromatography, High Pressure Liquid; Drug Administration Routes; Drug Residues / analysis; Drug Residues / metabolism; Drug Residues / pharmacokinetics; Kidney / drug effects; Liver / drug effects; Models, Biological; Thiamphenicol / administration & dosage; Thiamphenicol / analogs & derivatives; Thiamphenicol / analysis; Thiamphenicol / metabolism; Thiamphenicol / pharmacokinetics
Source: Web Of Science
Added: April 15, 2019
2019 journal article
Extralabel drug use in wildlife and game animals
Journal of the American Veterinary Medical Association, 255(5), 555–568.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Animals, Wild; Off-Label Use / veterinary
Source: Crossref
Added: August 13, 2021
2019 conference paper
Integration of Food Animal Residue Avoidance Databank (FARAD) Empirical Methods for Drug Withdrawal Interval Determination with a Mechanistic Population-Based Interactive Physiologically Based Pharmacokinetic (iPBPK) Modeling Platform: Example for Flunixin Meglumine Administration
The Toxicologist, 168(1), 191.
Event: 58th Society of Toxicology annual meeting & ToxExpo at Baltimore, Maryland on March 10-14, 2019
Source: NC State University Libraries
Added: August 13, 2021
2019 journal article
Integration of Food Animal Residue Avoidance Databank (FARAD) empirical methods for drug withdrawal interval determination with a mechanistic population-based interactive physiologically based pharmacokinetic (iPBPK) modeling platform: example for flunixin meglumine administration
Archives of Toxicology, 93(7), 1865–1880.
co-author countries:
United States of America 🇺🇸
author keywords: Flunixin; Interactive physiologically based pharmacokinetic (iPBPK) model; Food safety; Drug residues; Withdrawal intervals (WDIs); Food Animal Residue Avoidance Databank (FARAD)
MeSH headings : Animals; Animals, Domestic / metabolism; Clonixin / administration & dosage; Clonixin / analogs & derivatives; Clonixin / pharmacokinetics; Databases, Factual; Drug Residues / pharmacokinetics; Food Contamination / analysis; Food Contamination / prevention & control; Food Safety / methods; Models, Biological; Veterinary Drugs / administration & dosage; Veterinary Drugs / pharmacokinetics
Sources: Crossref, Web Of Science
Added: August 12, 2019
2019 journal article
Making Sense of Pharmacovigilance and Drug Adverse Event Reporting: Comparative Similarity Association Analysis Using AI Machine Learning Algorithms in Dogs and Cats
Topics in Companion Animal Medicine, 37, 100366.
co-author countries:
United States of America 🇺🇸
author keywords: similarity association; drug adverse events; artificial intelligence; pharmacovigilance machine learning algorithms; graphical LASSO; companion animals
MeSH headings : Algorithms; Animals; Artificial Intelligence; Cats; Dogs; Drug Combinations; Drug-Related Side Effects and Adverse Reactions / veterinary; Ivermectin / adverse effects; Ivermectin / analogs & derivatives; Machine Learning; Macrolides / adverse effects; Pharmacovigilance
Source: Crossref
Added: August 13, 2021
2019 journal article
Novel Data Sharing Agreement to Accelerate Big Data Translational Research Projects in the One Health Sphere
Topics in Companion Animal Medicine, 37, 100367.
co-author countries:
United States of America 🇺🇸
author keywords: data sharing; one health; public-private partnership; data analysis; legal issues; translational research; big data
MeSH headings : Animals; Big Data; Data Anonymization; Health Insurance Portability and Accountability Act; Humans; Information Dissemination / methods; One Health; Translational Research, Biomedical / organization & administration; United States
Source: Crossref
Added: August 13, 2021
2019 book
Science Breakthroughs to Advance Food and Agricultural Research by 2030
In SCIENCE BREAKTHROUGHS TO ADVANCE FOOD AND AGRICULTURAL RESEARCH BY 2030 (pp. 1–228).
Sources: Web Of Science, ORCID
Added: November 24, 2020
2018 conference paper
A general physiologically-based pharmacokinetic model for gold nanoparticles of different sizes with multiple administration routes in rats
The Toxicologist, 162(1), 526.
Event: 57th Society of Toxicology annual meeting and ToxExpo at San Antonio, Texas on March 11-15, 2018
Source: NC State University Libraries
Added: August 13, 2021
2018 chapter
Absorption, Distribution, Metabolism, and Elimination
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 8–40). Ames, Iowa: Wiley-Blackwell.
Ed(s): & M. Papich
Source: NC State University Libraries
Added: August 13, 2021
2018 chapter
Aminoglycoside Antibiotics
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 877–902). Ames, Iowa: Wiley-Blackwell.
Ed(s): & M. Papich
Source: NC State University Libraries
Added: August 13, 2021
2018 chapter
Antiarrhythmic Agents
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 537–552). Ames, Iowa: Wiley-Blackwell.
Ed(s): & M. Papich
Source: NC State University Libraries
Added: August 13, 2021
2018 conference paper
Application of population physiologically-based pharmacokinetic model for penicillin G in dairy cows to facilitate food safety assessment
The Toxicologist, 162(1), 526.
Event: 57th Society of Toxicology annual meeting at San Antonio, Texas on March 11-15, 2018
Source: NC State University Libraries
Added: August 13, 2021
2018 journal article
Automation and applications of the tolerance limit method in estimating meat withdrawal periods for veterinary drugs
COMPUTERS AND ELECTRONICS IN AGRICULTURE, 146, 125–135.
co-author countries:
United States of America 🇺🇸
author keywords: Withdrawal time calculator; R studio; Maximum residue limit; Tolerance; US FDA
Sources: Web Of Science, ORCID
Added: August 6, 2018
2018 chapter
Chemical Residues in Tissues of Food Animals
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 1469–1480). Ames, Iowa: Wiley-Blackwell.
Ed(s): & M. Papich
Source: NC State University Libraries
Added: August 13, 2021
2018 journal article
Consequences of fipronil exposure in egg-laying hens
Journal of the American Veterinary Medical Association, 253(1), 57–60.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animal Feed / analysis; Animals; Chickens / metabolism; Europe; Female; Food Contamination / prevention & control; Food Safety; Ovum / metabolism; Pesticides / adverse effects; Pyrazoles / adverse effects
Sources: Crossref, NC State University Libraries
Added: August 6, 2018
2018 chapter
Dermatopharmacology: Drugs Acting Locally on the Skin
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 1278–1301). Ames, Iowa: Wiley-Blackwell.
Ed(s): & M. Papich
Source: NC State University Libraries
Added: August 13, 2021
2018 chapter
Dosage Forms and Veterinary Feed Directives
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 1459–1464). Ames, Iowa: Wiley-Blackwell.
Ed(s): & M. Papich
Source: NC State University Libraries
Added: August 13, 2021
2018 journal article
Editorial
Journal of Veterinary Pharmacology and Therapeutics, 41(3), 355–355.
co-author countries:
United States of America 🇺🇸
MeSH headings : Editorial Policies; Periodicals as Topic; Veterinary Medicine
Sources: Web Of Science, Crossref
Added: August 6, 2018
2018 article
Extralabel drug use in small ruminants
Martin, K. L., Clapham, M. O., Davis, J. L., Baynes, R. E., Lin, Z., Vickroy, T. W., … Tell, L. A. (2018, October 15). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 253, pp. 1001–1009.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Drug Residues; Goat Diseases / drug therapy; Goats; Legislation, Drug; Off-Label Use; Sheep; Sheep Diseases / drug therapy; United States; United States Food and Drug Administration; Veterinary Drugs / administration & dosage; Veterinary Drugs / pharmacokinetics
Source: Web Of Science
Added: October 16, 2018
2018 conference paper
Impact of natural compounds on dermal absorption for consumer products and their computational prediction
The Toxicologist, 162(1), 179.
Event: 57th Society of Toxicology annual meeting & ToxExpo at San Antonio, Texas on March 11-15, 2018
Source: NC State University Libraries
Added: August 13, 2021
2018 journal article
Mathematical modeling and simulation in animal health. Part III: Using nonlinear mixed-effects to characterize and quantify variability in drug pharmacokinetics
Journal of Veterinary Pharmacology and Therapeutics, 41(2), 171–183.
co-author countries:
Australia 🇦🇺 Switzerland 🇨🇭 France 🇫🇷 United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: covariates; nonlinear mixed effects; population pharmacokinetics; sparse sampling; veterinary medicine
MeSH headings : Animal Diseases / drug therapy; Animals; Models, Theoretical; Nonlinear Dynamics; Pharmacokinetics
Source: Crossref
Added: August 13, 2021
2018 journal article
Modeling gold nanoparticle biodistribution after arterial infusion into perfused tissue: effects of surface coating, size and protein corona
Nanotoxicology, 12(10), 1093–1112.
co-author countries:
United States of America 🇺🇸
Contributors: *, M. Jaberi-Douraki *, J. Lillich*, T. Azizi *, H. Joo*, K. Choi*, R. Thakkar*, N. Monteiro-Riviere*
author keywords: Biodistribution; gold nanoparticles; cell uptake; skin; pharmacokinetics; nanoparticle vascular distribution
MeSH headings : Animals; Epigastric Arteries; Female; Free Tissue Flaps; Gold / administration & dosage; Gold / chemistry; Gold / pharmacokinetics; Humans; Infusions, Intra-Arterial; Metal Nanoparticles / administration & dosage; Metal Nanoparticles / chemistry; Models, Biological; Nanomedicine; Particle Size; Perfusion; Polyethylene Glycols / chemistry; Polyethyleneimine / chemistry; Protein Corona / chemistry; Skin / blood supply; Skin / metabolism; Surface Properties; Swine; Thioctic Acid / chemistry; Tissue Distribution
Sources: Crossref, ORCID
Added: June 27, 2019
2018 chapter
Pharmacokinetics
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 41–64). Ames, Iowa: Wiley-Blackwell.
Ed(s): & M. Papich
Source: NC State University Libraries
Added: August 13, 2021
2018 journal article
Probabilistic Physiologically Based Pharmacokinetic Model for Penicillin G in Milk From Dairy Cows Following Intramammary or Intramuscular Administrations
Toxicological Sciences, 164(1), 85–100.
co-author countries:
United States of America 🇺🇸
author keywords: PBPK modeling; dairy cows; food safety; drug residue; Food Animal Residue Avoidance Databank (FARAD); penicillin
MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / pharmacokinetics; Cattle; Drug Residues / analysis; Female; Food Contamination / analysis; Injections, Intramuscular; Mammary Glands, Animal / metabolism; Meat / analysis; Milk / chemistry; Models, Biological; Penicillin G / administration & dosage; Penicillin G / pharmacokinetics
Source: Crossref
Added: August 13, 2021
2018 journal article
Probabilistic risk assessment of gold nanoparticles after intravenous administration by integrating in vitro and in vivo toxicity with physiologically based pharmacokinetic modeling
Nanotoxicology, 12(5), 453–469.
co-author countries:
United States of America 🇺🇸
Contributors: Y. Cheng *, *, N. Monteiro-Riviere* & Z. Lin *
author keywords: Gold nanoparticle; computational nanotoxicology; physiologically based pharmacokinetic modeling; probabilistic risk assessment
MeSH headings : Administration, Intravenous; Animals; Bayes Theorem; Gold / administration & dosage; Gold / pharmacokinetics; Gold / toxicity; Humans; Metal Nanoparticles / toxicity; Models, Biological; Monte Carlo Method; Risk Assessment
Sources: Crossref, ORCID
Added: June 27, 2019
2018 conference paper
Probabilistic risk assessment of gold nanoparticles by integrating in vitro and in vivo toxicity with physiologically-based pharmacokinetic modeling
The Toxicologist, 162(1), 526.
Event: 57th Society of Toxicology annual meeting and ToxExpo at San Antonio, Texas on March 11-15, 2018
Source: NC State University Libraries
Added: August 13, 2021
2018 chapter
Tetracycline Antibiotics
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 858–876). Ames, Iowa: Wiley-Blackwell.
Ed(s): & M. Papich
Source: NC State University Libraries
Added: August 13, 2021
2018 journal article
Variation in fluoroquinolone pharmacodynamic parameter values among isolates of two bacterial pathogens of bovine respiratory disease
Scientific Reports, 8(1).
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / therapeutic use; Bovine Respiratory Disease Complex / drug therapy; Bovine Respiratory Disease Complex / microbiology; Cattle; Fluoroquinolones / pharmacology; Fluoroquinolones / therapeutic use; Mannheimia haemolytica / drug effects; Mannheimia haemolytica / genetics; Mannheimia haemolytica / isolation & purification; Microbial Sensitivity Tests; Models, Biological; Pasteurella multocida / drug effects; Pasteurella multocida / genetics; Pasteurella multocida / isolation & purification; Phenotype
Source: Crossref
Added: August 13, 2021
2018 book
Veterinary Pharmacology and Therapeutics
(10th ed.). Ames, Iowa: Wiley-Blackwell.
Ed(s): & M. Papich
Source: NC State University Libraries
Added: August 13, 2021
2018 chapter
Veterinary Pharmacology: An Introduction to the Discipline
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 3–7). Ames, Iowa: Wiley-Blackwell.
Ed(s): & M. Papich
Source: NC State University Libraries
Added: August 13, 2021
2017 journal article
Avoiding violative flunixin meglumine residues in cattle and swine
Journal of the American Veterinary Medical Association, 250(2), 182–189.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / chemistry; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Cattle; Clonixin / analogs & derivatives; Clonixin / chemistry; Clonixin / pharmacokinetics; Drug Residues / pharmacokinetics; Swine
Sources: Crossref, NC State University Libraries, ORCID
Added: August 6, 2018
2017 journal article
Biocorona formation on gold nanoparticles modulates human proximal tubule kidney cell uptake, cytotoxicity and gene expression
Toxicology in Vitro, 42, 150–160.
co-author countries:
United States of America 🇺🇸
author keywords: Gold nanoparticles; Human proximal tubule cells; Protein corona; Cellular uptake; Gene expression; Mechanisms of toxicity
MeSH headings : Cells, Cultured; Cytokines / metabolism; Gene Expression / drug effects; Gold / administration & dosage; Gold / chemistry; Gold / toxicity; Humans; Kidney Tubules, Proximal / cytology; Metal Nanoparticles / administration & dosage; Metal Nanoparticles / chemistry; Metal Nanoparticles / toxicity; Plasma / chemistry; Polyethylene Glycols / chemistry; Polyethyleneimine / chemistry; Protein Corona / chemistry; Serum Albumin / chemistry; Thioctic Acid / chemistry
Sources: Crossref, ORCID
Added: June 27, 2019
2017 journal article
Biological Surface Adsorption Index of Nanomaterials: Modelling Surface Interactions of Nanomaterials with Biomolecules
Advances in Experimental Medicine and Biology, 947, 207–253.
co-author countries:
United States of America 🇺🇸
author keywords: Nanoparticles; Surface interactions; BSAI; Bicorona; Physicochemistry; In situ characterization
MeSH headings : Adsorption; Environment; Models, Biological; Models, Theoretical; Nanostructures / chemistry; Nanotechnology / methods; Surface Properties
Source: Web Of Science
Added: February 5, 2022
2017 journal article
Considerations for extralabel drug use in calves
Journal of the American Veterinary Medical Association, 250(11), 1275–1282.
MeSH headings : Animals; Animals, Newborn; Cattle; Drug Labeling; Drug Residues; Food Contamination; Meat; Milk; Veterinary Drugs / administration & dosage; Veterinary Drugs / pharmacokinetics
Sources: Crossref, Web Of Science, ORCID
Added: August 6, 2018
2017 chapter
Dermatotoxicology: Computational approaches to predicting absorption of complex topical chemical mixtures
In S. Ekins (Ed.), Computational Toxicology (2nd ed., pp. 269–290). New York: John Wiley.
Ed(s): S. Ekins
Source: NC State University Libraries
Added: February 5, 2022
2017 journal article
Development and application of a population physiologically based pharmacokinetic model for penicillin G in swine and cattle for food safety assessment
Food and Chemical Toxicology, 107, 74–87.
co-author countries:
United States of America 🇺🇸
author keywords: Physiologically based pharmacokinetic (PBPK) model; Food safety; Food animal residue avoidance databank (FARAD); Penicillin; Drug residue; Extralabel withdrawal interval
MeSH headings : Animals; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacokinetics; Cattle; Drug Residues / chemistry; Drug Residues / pharmacokinetics; Food Safety; Kidney / chemistry; Liver / chemistry; Meat / analysis; Models, Biological; Muscle, Skeletal / chemistry; Penicillin G / chemistry; Penicillin G / pharmacokinetics; Swine
Source: Crossref
Added: October 1, 2021
2017 journal article
Guide to FARAD resources: historical and future perspectives
Journal of the American Veterinary Medical Association, 250(10), 1131–1139.
MeSH headings : Animal Husbandry; Animals; Consumer Product Safety; Databases, Factual; Drug Residues; Food Contamination; Meat; United States; United States Department of Agriculture
Sources: Crossref, Web Of Science
Added: August 6, 2018
2017 journal article
Modulation of topical chemical absorption by 14 natural compounds: a quantitative structure permeation (QSPR) analysis of components often found in topical preparations
Cutaneous and Ocular Toxicology, 36(3), 237–252.
Source: NC State University Libraries
Added: February 5, 2022
2017 chapter
Multi-Walled Carbon Nanotube Exposure Alters Protein Expression in Human Keratinocytes
In Nanomedicine in Cancer (pp. 461–485).
Source: Crossref
Added: December 24, 2021
2017 journal article
Nano in-vitro cellular uptake simulator (NICUS): a model to quantitate nanomaterial endocytosis kinetics and intracellular dose
The Toxicologist, 156, 303.
Source: NC State University Libraries
Added: February 5, 2022
2017 journal article
NanoEHS beyond toxicity – focusing on biocorona
Environmental Science: Nano, 4(7), 1433–1454.
co-author countries:
Australia 🇦🇺 China 🇨🇳 United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
Source: Crossref
Added: October 1, 2021
2017 journal article
Performance Assessment and Translation of Physiologically Based Pharmacokinetic Models From acslX to Berkeley Madonna, MATLAB, and R Language: Oxytetracycline and Gold Nanoparticles As Case Examples
Toxicological Sciences, 158(1), 23–35.
author keywords: acslX; Berkeley Madonna; MATLAB; PBPK modeling; R language
MeSH headings : Animals; Dogs; Gold / blood; Gold / chemistry; Gold / pharmacokinetics; Metal Nanoparticles / chemistry; Models, Biological; Oxytetracycline / blood; Oxytetracycline / pharmacokinetics; Swine; Tissue Distribution
Source: Crossref
Added: October 1, 2021
2017 journal article
Pharmacokinetics of Mequindox and Its Marker Residue 1,4-Bisdesoxymequindox in Swine Following Multiple Oral Gavage and Intramuscular Administration: An Experimental Study Coupled with Population Physiologically Based Pharmacokinetic Modeling
Journal of Agricultural and Food Chemistry, 65(28), 5768–5777.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: food safety; mequindox; physiologically based pharmacokinetic (PBPK) modeling; quinoxaline-N,N-dioxide antibiotics; swine
MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / pharmacokinetics; Drug Residues / pharmacokinetics; Injections, Intramuscular; Liver / metabolism; Quinoxalines / administration & dosage; Quinoxalines / pharmacokinetics; Swine; Tissue Distribution; Veterinary Drugs / administration & dosage; Veterinary Drugs / pharmacokinetics
Source: Crossref
Added: October 1, 2021
2017 journal article
Surface chemistry of gold nanoparticles determines the biocorona composition impacting cellular uptake, toxicity and gene expression profiles in human endothelial cells
Nanotoxicology, 11(4), 507–519.
co-author countries:
United States of America 🇺🇸
Contributors: P. Chandran *, * & N. Monteiro-Riviere*
author keywords: Biocorona; gold nanoparticles; surface chemistry; endothelial cells; mechanistic toxicology
MeSH headings : Albumins / metabolism; Cell Survival / drug effects; Circular Dichroism; Endothelial Cells / drug effects; Endothelial Cells / metabolism; Gold / chemistry; Gold / toxicity; Human Umbilical Vein Endothelial Cells; Humans; Metal Nanoparticles / chemistry; Metal Nanoparticles / toxicity; Particle Size; Polyethylene Glycols / chemistry; Polyethyleneimine / chemistry; Protein Corona / metabolism; Proteomics; Surface Properties; Transcriptome / drug effects
Sources: Web Of Science, Crossref, ORCID
Added: April 29, 2021
2017 journal article
Zinc Oxide Nanoparticle–Poly I:C RNA Complexes: Implication as Therapeutics against Experimental Melanoma
Molecular Pharmaceutics, 14(3), 614–625.
co-author countries:
United States of America 🇺🇸
author keywords: zinc oxide nanoparticles (ZnO-NPs); poly I:C RNA (pIC); binding parameters; antimelanoma; immunology
MeSH headings : Animals; Antineoplastic Agents / pharmacology; Biomarkers, Tumor / metabolism; Cell Death / drug effects; Cell Line, Tumor; Humans; Interferon-gamma / metabolism; Interleukin-6 / metabolism; MAP Kinase Kinase 4 / metabolism; Melanoma, Experimental / drug therapy; Melanoma, Experimental / metabolism; Mice; Mice, Inbred BALB C; Nanoparticles / administration & dosage; Poly I-C / pharmacology; Proto-Oncogene Proteins c-akt / metabolism; RNA / pharmacology; Zinc Oxide / pharmacology
Source: Crossref
Added: October 1, 2021
2016 journal article
A computational framework for interspecies pharmacokinetics, exposure and toxicity assessment of gold nanoparticles
Nanomedicine, 11(2), 107–119.
co-author countries:
United States of America 🇺🇸
Contributors: Z. Lin *, N. Monteiro-Riviere* , R. Kannan* & *
author keywords: biodistribution; computational nanotoxicology; endocytosis; nanomaterials; PBPK modeling; physiologically based pharmacokinetic modeling; phagocytosis; toxicokinetics
MeSH headings : Animals; Cell Survival / drug effects; Computer Simulation; Dose-Response Relationship, Drug; Environmental Exposure / adverse effects; Gold / pharmacokinetics; Gold / toxicity; Humans; Metabolic Clearance Rate; Mice; Models, Biological; Nanoparticles / toxicity; Rats; Species Specificity; Swine; Tissue Distribution; Toxicity Tests / methods
Sources: Crossref, ORCID, NC State University Libraries
Added: April 29, 2021
2016 journal article
A new voyage begins: welcoming new editors and the launching of Pharmacokinetic Reports
Journal of Veterinary Pharmacology and Therapeutics, 39, 317.
Source: NC State University Libraries
Added: February 5, 2022
2016 journal article
A physiological based pharmacokinetic model for polyethylene glycol-coated gold nanoparticles of different sizes in adult mice
Nanotoxicology, 10, 162–172.
Source: NC State University Libraries
Added: February 5, 2022
2016 journal article
Assessment of penetrant and vehicle mixture properties on transdermal permeability using a mixed effect pharmacokinetic model of ex vivo porcine skin
Biopharmaceutics & Drug Disposition, 37(7), 387–396.
co-author countries:
United States of America 🇺🇸
author keywords: quantitative structure property relationship; transdermal permeability; vehicle mixture; ex vivo; mixed-effect model
MeSH headings : Administration, Cutaneous; Animals; Models, Biological; Permeability; Pharmaceutical Preparations / metabolism; Quantitative Structure-Activity Relationship; Skin / metabolism; Skin Absorption; Swine
Sources: Crossref, Web Of Science
Added: August 6, 2018
2016 journal article
Biological and environmental surface interactions of nanomaterials: characterization, modeling, and prediction
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 9(3), e1440.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Biocompatible Materials; Biomedical Research; Humans; Mice; Models, Theoretical; Molecular Dynamics Simulation; Nanostructures; Structure-Activity Relationship; Surface Properties
Source: Crossref
Added: September 30, 2021
2016 conference paper
Biological surface adsorption index: environmental applications and parallel molecular dynamics simulations
Proceedings of 8th International Nanotoxicology Conference, 72.
Event: 8th International Nanotoxicology Conference
Source: NC State University Libraries
Added: February 5, 2022
2016 conference paper
Caveats to making in vitro to in vivo and interspecies extrapolations of nanoparticle biological interactions using in silico computational modeling
The 51st Midwest Regional Meeting of the American Chemical Society, 47.
Event: 51st Midwest Regional Meeting of the American Chemical Society at Orlando, FL
Source: NC State University Libraries
Added: February 5, 2022
2016 journal article
Estimation of tulathromycin depletion in plasma and milk after subcutaneous injection in lactating dairy goats using a nonlinear mixed-effect pharmacokinetic modeling approach
BMC Veterinary Research, 12(258).
Source: NC State University Libraries
Added: February 5, 2022
2016 journal article
Exploring Post-Treatment Reversion of Antimicrobial Resistance in Enteric Bacteria of Food Animals as a Resistance Mitigation Strategy
Foodborne Pathogens and Disease, 13(11), 610–617.
co-author countries:
United States of America 🇺🇸
author keywords: pre-harvest food safety; antimicrobial use in livestock; antimicrobial resistance in bacteria of animal origin; antimicrobial resistance ecology; population pharmacokinetics
MeSH headings : Animals; Anti-Infective Agents / adverse effects; Anti-Infective Agents / pharmacokinetics; Anti-Infective Agents / therapeutic use; Drug Residues / standards; Drug Residues / toxicity; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae / drug effects; Enterobacteriaceae / growth & development; Enterobacteriaceae / isolation & purification; Enterobacteriaceae Infections / drug therapy; Enterobacteriaceae Infections / microbiology; Enterobacteriaceae Infections / prevention & control; Enterobacteriaceae Infections / veterinary; Escherichia coli / drug effects; Escherichia coli / growth & development; Escherichia coli / isolation & purification; Escherichia coli Infections / drug therapy; Escherichia coli Infections / microbiology; Escherichia coli Infections / prevention & control; Escherichia coli Infections / veterinary; Evidence-Based Practice; Feces / microbiology; Food Contamination / prevention & control; Food Safety; Foodborne Diseases / drug therapy; Foodborne Diseases / microbiology; Foodborne Diseases / prevention & control; Guidelines as Topic; Humans; Livestock / growth & development; Livestock / microbiology; Secondary Prevention / standards; Tissue Distribution
Source: Crossref
Added: October 1, 2021
2016 journal article
Health concerns and management of select veterinary drug residues
Food and Chemical Toxicology, 88, 112–122.
co-author countries:
United States of America 🇺🇸
author keywords: Drug; Veterinary; Residue; Adverse; Livestock
MeSH headings : Animals; Carcinogens; Drug Residues / adverse effects; Humans; Veterinary Drugs / chemistry; Veterinary Drugs / metabolism; Veterinary Drugs / pharmacokinetics
Source: Crossref
Added: February 24, 2020
2016 journal article
Human food safety implications of variation in food animal drug metabolism
Scientific Reports, 6(27907).
Source: NC State University Libraries
Added: February 5, 2022
2016 journal article
Influence of some plant extracts on the transdermal absorption and penetration of marker residues
Cutaneous and Ocular Toxicology, 30, 1–7.
Source: NC State University Libraries
Added: February 5, 2022
2016 journal article
Limitation of MIC as sole metric of pharmacodynamic response across the range of antimicrobial susceptibility within a single bacterial species
Scientific Reports, 6(37907).
Source: NC State University Libraries
Added: February 5, 2022
2016 journal article
Mathematical modeling and simulation in animal health – Part II : principles, methods, applications, and value of physiologically based pharmacokinetic modeling in veterinary medicine and food safety assessment
Journal of Veterinary Pharmacology and Therapeutics, 39(5), 421–438.
co-author countries:
Switzerland 🇨🇭 United States of America 🇺🇸
MeSH headings : Animals; Food Safety / methods; Models, Statistical; Pharmacokinetics; Veterinary Medicine / methods; Veterinary Medicine / statistics & numerical data
Source: Crossref
Added: October 1, 2021
2016 journal article
Mathematical modeling and simulation in animal health. Part I: Moving beyond pharmacokinetics
Journal of Veterinary Pharmacology and Therapeutics, 39(3), 213–223.
co-author countries:
Switzerland 🇨🇭 Sweden 🇸🇪 United States of America 🇺🇸
MeSH headings : Animals; Computer Simulation; Models, Biological; Veterinary Drugs / pharmacokinetics
Source: Crossref
Added: October 1, 2021
2016 journal article
Mechanistic Toxicity Assessment of Hexahydroisohumulone in Canine Hepatocytes, Renal Proximal Tubules, Bone Marrow-Derived Mesenchymal Stem Cells, and Enterocyte-like Cells
International Journal of Veterinary Health Science & Research, 4(2), 88–103.
Sources: Crossref, ORCID
Added: April 29, 2021
2016 journal article
Mechanistic toxicity assessment of hexahydroisohumulone in canine hepatocytes, renal proximal tubules, and enterocyte like-cells
The Toxicologist, 150, 487.
Source: NC State University Libraries
Added: February 5, 2022
2016 journal article
Modulation of Chemical Dermal Absorption by 14 Natural Products: A Quantitative Structure Permeation (QSPR) Analysis of Components Often Found in Topical Cosmeceuticals
Cutaneous and Ocular Toxicology, 36(3), 237–252.
co-author countries:
Brazil 🇧🇷 United States of America 🇺🇸
author keywords: Absorption; compounds of natural origin; mathematical modeling; mixtures; QSPR; skin
MeSH headings : Administration, Topical; Animals; Biological Products / chemistry; Biological Products / pharmacology; Caffeine / chemistry; Caffeine / pharmacokinetics; Cosmetics / chemistry; Cosmetics / pharmacokinetics; Female; In Vitro Techniques; Models, Biological; Permeability; Quantitative Structure-Activity Relationship; Salicylic Acid / chemistry; Salicylic Acid / pharmacokinetics; Skin / metabolism; Skin Absorption / drug effects; Swine
Source: Web Of Science
Added: February 5, 2022
2016 journal article
Observations on macrolide resistance in field isolates collected from bovine respiratory disease cases
Veterinary Microbiology, 192, 186–193.
Source: NC State University Libraries
Added: February 5, 2022
2016 journal article
Oxidative stress response in canine in vitro liver, kidney and intestinal models with seven potential dietary ingredients
Toxicology Letters, 241, 49–59.
co-author countries:
United States of America 🇺🇸
Contributors: K. Choi*, M. Ortega*, B. Jeffery, * & N. Monteiro-Riviere*
author keywords: In vitro canine culture systems; Multiple organ-derived cells; Dietary ingredients; Organ-specific oxidative stress
MeSH headings : Animals; Antioxidants / chemistry; Antioxidants / pharmacology; Bone Marrow Cells / drug effects; Bone Marrow Cells / metabolism; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; Food; Food Analysis; Hepatocytes / drug effects; Intestinal Mucosa / metabolism; Intestines / drug effects; Kidney / drug effects; Kidney / metabolism; Kidney Tubules, Proximal / cytology; Kidney Tubules, Proximal / drug effects; Liver / drug effects; Liver / metabolism; Mesenchymal Stem Cells / drug effects; Mesenchymal Stem Cells / metabolism; Oxidants / toxicity; Oxidative Stress / drug effects
Sources: Crossref, ORCID
Added: April 29, 2021
2016 journal article
Pharmacokinetics and tissue elimination of flunixin in veal calves
American Journal of Veterinary Research, 77(6), 634–640.
co-author countries:
France 🇫🇷 Japan 🇯🇵 United States of America 🇺🇸
MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / blood; Anti-Inflammatory Agents, Non-Steroidal / chemistry; Anti-Inflammatory Agents, Non-Steroidal / metabolism; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Area Under Curve; Cattle / blood; Clonixin / analogs & derivatives; Clonixin / blood; Clonixin / chemistry; Clonixin / metabolism; Clonixin / pharmacokinetics; Drug Residues; Half-Life; Liver / chemistry; Muscle, Skeletal / chemistry; Muscle, Skeletal / metabolism
Sources: Crossref, Web Of Science, ORCID
Added: August 6, 2018
2016 conference paper
Physiological based pharmacokinetic (PBPK) modeling of nanomaterials: Why is quantitation and anatomical / physiological reality so important?
Proceedings of 8th International Nanotoxicology Conference, 385.
Event: 8th International Nanotoxicology Conference
Source: NC State University Libraries
Added: February 5, 2022
2016 chapter
Potential mechanism of toxicity of hexahydroisohumulone in an in vitro canine model
Presented at the WINNS 2016 – Growing Science in Pet Nutrition.
Event: WINNS 2016 – Growing Science in Pet Nutrition
Source: NC State University Libraries
Added: February 5, 2022
2016 conference paper
Predicting and modeling in vivo nanoparticle biodistribution: caveats to making in vitro and rodent interspecies extrapolations
11th International Particle Toxicology Conference, 54.
Event: 11th International Particle Toxicology Conference
Source: NC State University Libraries
Added: February 5, 2022
2016 journal article
Protein corona modulation of hepatocyte uptake and molecular mechanisms of gold nanoparticle toxicity
Nanotoxicology, 11(1), 64–75.
co-author countries:
United States of America 🇺🇸
Contributors: K. Choi*, * & N. Monteiro-Riviere*
author keywords: Gold nanoparticles; human hepatocytes; cell uptake; cytochrome P450; mechanisms of action
MeSH headings : Albumins / chemistry; Blood Proteins / chemistry; Cell Survival / drug effects; Dose-Response Relationship, Drug; Gene Expression Profiling; Gold / chemistry; Gold / metabolism; Gold / toxicity; Hepatocytes / drug effects; Hepatocytes / metabolism; Humans; Metal Nanoparticles / chemistry; Metal Nanoparticles / toxicity; Polyethylene Glycols / chemistry; Polyethyleneimine / chemistry; Protein Corona / metabolism; Reactive Oxygen Species / metabolism; Transcriptome / drug effects
Sources: Crossref, ORCID
Added: April 27, 2021
2016 journal article
Protocol for diversion of confirmed positive bulk raw milk tankers to calf ranches – A review of the Pharmacokinetics of tetracyclines and sulfonamides in veal calves
Animal Health Research Reviews, 17(2), 127–136.
co-author countries:
United States of America 🇺🇸
author keywords: tetracycline; chlortetracycline; oxytetracycline; sulfonamide; veal; residue; discard milk
MeSH headings : Animals; Anti-Bacterial Agents; Cattle / metabolism; Drug Residues; Milk / chemistry; Sulfonamides / pharmacokinetics; Tetracyclines / chemistry; Tetracyclines / pharmacokinetics
Source: Crossref
Added: October 1, 2021
2016 journal article
Quantification of nanoparticle pesticide adsorption: computational approaches based on experimental data
Nanotoxicology, 10(8), 1118–1128.
co-author countries:
United States of America 🇺🇸
Contributors: R. Chen *, Y. Zhang*, N. Monteiro-Riviere* & *
author keywords: BSAI; in situ characterization; nanoparticles; pesticide; surface physicochemistry
MeSH headings : Adsorption; Models, Theoretical; Nanoparticles / analysis; Nanoparticles / chemistry; Neural Networks, Computer; Pesticides / analysis; Pesticides / chemistry; Principal Component Analysis; Surface Properties
Sources: Crossref, ORCID
Added: April 29, 2021
2016 journal article
Residue concerns following exposure to livestock to oil and petroleum products
Journal of the American Veterinary Medical Association, 248, 145–146.
Source: NC State University Libraries
Added: February 5, 2022
2016 journal article
Screening and Confirmatory Analyses of Flunixin in Tissues and Bodily Fluids after Intravenous or Intramuscular Administration to Cull Dairy Cows with or without Lipopolysaccharide Challenge
Journal of Agricultural and Food Chemistry, 64(1), 336–345.
co-author countries:
United States of America 🇺🇸
author keywords: flunixin; ELISA; route of administration; concentration; food safety
MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / administration & dosage; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Cattle; Cattle Diseases / blood; Cattle Diseases / drug therapy; Cattle Diseases / metabolism; Cattle Diseases / urine; Clonixin / administration & dosage; Clonixin / analogs & derivatives; Clonixin / pharmacokinetics; Drug Residues / pharmacokinetics; Female; Injections, Intramuscular; Kidney / chemistry; Kidney / metabolism; Liver / chemistry; Liver / metabolism; Milk / chemistry; Muscles / chemistry; Muscles / metabolism; Tissue Distribution
Sources: Crossref, Web Of Science
Added: August 6, 2018
2016 chapter
The effects of vehicle mixtures on transdermal absorption: thermodynamics, mechanism, assessment and prediction
In N. Dragicevic-Curic & H. I. Maibach (Eds.), Percutaneous Penetration Enhancers Drug Penetration Into/Through the Skin: Methodology and General Considerations (pp. 95–118). New York: Springer.
Ed(s): N. Dragicevic-Curic & H. Maibach
Source: NC State University Libraries
Added: February 5, 2022
2016 journal article
Toxicological effects of pet food ingredients on canine bone marrow-derived mesenchymal stem cells and enterocyte-like cells
Journal of Applied Toxicology, 36(2), 189–198.
co-author countries:
United States of America 🇺🇸
Contributors: M. Ortega*, B. Jeffery, * & N. Monteiro-Riviere*
author keywords: canine; bone marrow stem cells; enterocyte like cells; adult stem cell differentiation; essential oils; cytotoxicity; mesenchymal stem cells; in vitro
MeSH headings : Acrolein / analogs & derivatives; Acrolein / toxicity; Animal Feed / toxicity; Animals; Bone Marrow / drug effects; Citric Acid / toxicity; Clove Oil / toxicity; Cytotoxins / toxicity; Dogs; Enterocytes / drug effects; Eugenol / toxicity; Ginger / toxicity; Guanosine Monophosphate / toxicity; Inosine Monophosphate / toxicity; Mesenchymal Stem Cells / drug effects; Oils, Volatile / toxicity; Pets; Plant Oils / toxicity; Plant Roots / toxicity; Sorbose / toxicity; Thymol / toxicity
Sources: Crossref, ORCID
Added: April 29, 2021
2015 journal article
A Framework for Meta-Analysis of Veterinary Drug Pharmacokinetic Data Using Mixed Effect Modeling
Journal of Pharmaceutical Sciences, 104(4), 1230–1239.
co-author countries:
United States of America 🇺🇸
author keywords: meta-analysis; nonlinear mixed-effect modeling; pharmacokinetics; population pharmacokinetics; veterinary medicine; drug depletion; drug withdrawal time; clearance; distribution; formulation
MeSH headings : Animals; Computer Simulation; Data Mining; Databases, Factual; Humans; Meta-Analysis as Topic; Models, Biological; Models, Statistical; Nonlinear Dynamics; Reproducibility of Results; Species Specificity; Veterinary Drugs / administration & dosage; Veterinary Drugs / pharmacokinetics
Source: Crossref
Added: December 24, 2021
2015 journal article
Canine renal proximal tubule cells as an in vitro model for toxicity assessment of pet food ingredients
The Toxicologist, 144, 490.
Source: NC State University Libraries
Added: February 5, 2022
2015 journal article
Comparative In Vitro Cytotoxicity of 20 Potential Food Ingredients in Canine Liver, Kidney, Bone Marrow-Derived Mesenchymal Stem Cells, and Enterocyte-like Cells
Applied In Vitro Toxicology, 1(4), 276–288.
co-author countries:
United States of America 🇺🇸
Sources: Crossref, ORCID, NC State University Libraries
Added: April 30, 2021
2015 journal article
Comparison of pharmacokinetics and milk elimination of flunixin in healthy cows and cows with mastitis
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 246(1), 118–125.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Anti-Inflammatory Agents, Non-Steroidal / blood; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Cattle; Cephalosporins / therapeutic use; Clonixin / analogs & derivatives; Clonixin / blood; Clonixin / pharmacokinetics; Female; Mastitis, Bovine / drug therapy; Mastitis, Bovine / metabolism; Milk / chemistry
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Determination of thermodynamic solubility of active pharmaceutical ingredients for veterinary species: a new USP general chapter
Pharmacopeial Forum, 41(3).
Source: NC State University Libraries
Added: February 5, 2022
2015 journal article
Development and Application of a Multiroute Physiologically Based Pharmacokinetic Model for Oxytetracycline in Dogs and Humans
Journal of Pharmaceutical Sciences, 104(1), 233–243.
co-author countries:
United States of America 🇺🇸
author keywords: oxytetracycline; physiologically based pharmacokinetic (PBPK) modeling; dogs; tetracycline antibiotics; Food Animal Residue Avoidance Databank (FARAD); computational ADME; mathematical model; pharmacokinetics; in silico modeling; disposition
MeSH headings : Administration, Oral; Animals; Animals, Inbred Strains; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / metabolism; Anti-Bacterial Agents / pharmacokinetics; Computational Biology; Computer Simulation; Databases, Pharmaceutical; Dogs; Dose-Response Relationship, Drug; Humans; Injections, Intramuscular; Injections, Intravenous; Kidney / metabolism; Models, Biological; Oxytetracycline / administration & dosage; Oxytetracycline / blood; Oxytetracycline / metabolism; Oxytetracycline / pharmacokinetics; Pharmacology, Clinical / methods; Physiology, Comparative / methods; Renal Elimination; Reproducibility of Results; Species Specificity; Tissue Distribution; Veterinary Medicine / methods
Source: Crossref
Added: October 1, 2021
2015 conference paper
Development of a physiologically-relevant multivariate nanoparticle molecular interaction fingerprint
Presented at the 250th American Chemical Society National Meeting, Boston, MA.
Event: 250th American Chemical Society National Meeting at Boston, MA
Source: NC State University Libraries
Added: February 5, 2022
2015 journal article
Differential effects of some natural compounds on the transdermal absorption and penetration of caffeine and salicylic acid
International Journal of Pharmaceutics, 483(1-2), 151–157.
co-author countries:
United States of America 🇺🇸
author keywords: Natural substance; Skin; Penetration; Drugs
MeSH headings : Animals; Biological Products / chemistry; Biological Products / pharmacology; Caffeine / chemistry; Caffeine / pharmacokinetics; Carbon Radioisotopes; Diffusion; Dose-Response Relationship, Drug; Female; Molecular Structure; Permeability / drug effects; Salicylic Acid / chemistry; Salicylic Acid / pharmacokinetics; Skin Absorption / drug effects; Structure-Activity Relationship; Swine
Sources: Crossref, NC State University Libraries
Added: December 24, 2021
2015 journal article
Egg residue considerations during the treatment of backyard poultry
Journal of the American Veterinary Medical Association, 247(12), 1388–1395.
MeSH headings : Animal Feed; Animal Husbandry; Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / pharmacokinetics; Anti-Bacterial Agents / therapeutic use; Chickens; Drug Residues; Eggs / analysis; Poultry Diseases / drug therapy; Turkeys; United States; United States Food and Drug Administration
Sources: Crossref, Web Of Science
Added: August 6, 2018
2015 journal article
Estimation of residue depletion of cyadox and its marker residue in edible tissues of pigs using physiologically based pharmacokinetic modeling
Food Additives & Contaminants: Part A, 32(12), 2002–2017.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: cyadox; 1,4-bisdesoxycyadox; PBPK modelling; tissue depletion; residue prediction; sensitivity analysis; Monte Carlo analysis
MeSH headings : Adipose Tissue / chemistry; Adipose Tissue / metabolism; Animal Feed / analysis; Animals; Anti-Infective Agents / isolation & purification; Anti-Infective Agents / metabolism; Anti-Infective Agents / pharmacokinetics; Biotransformation; Chromatography, Liquid; Drug Residues / isolation & purification; Drug Residues / metabolism; Food Analysis / methods; Kidney / chemistry; Kidney / metabolism; Liver / chemistry; Liver / metabolism; Models, Statistical; Monte Carlo Method; Muscle, Skeletal / chemistry; Muscle, Skeletal / metabolism; Quinoxalines / isolation & purification; Quinoxalines / metabolism; Quinoxalines / pharmacokinetics; Swine; Tandem Mass Spectrometry; Veterinary Drugs / isolation & purification; Veterinary Drugs / metabolism; Veterinary Drugs / pharmacokinetics
Source: Web Of Science
Added: February 5, 2022
2015 journal article
Excretory, Secretory, and Tissue Residues after Label and Extra-label Administration of Flunixin Meglumine to Saline- or Lipopolysaccharide-Exposed Dairy Cows
Journal of Agricultural and Food Chemistry, 63(19), 4893–4901.
co-author countries:
United States of America 🇺🇸
author keywords: dairy; extra-label; flunixin; holstein; liver; metabolite ratio; milk; residue
MeSH headings : Adipose Tissue / chemistry; Animals; Anti-Inflammatory Agents, Non-Steroidal / administration & dosage; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Cattle; Clonixin / administration & dosage; Clonixin / analogs & derivatives; Clonixin / analysis; Clonixin / pharmacokinetics; Drug Labeling; Drug Residues / analysis; Drug Residues / pharmacokinetics; Female; Inflammation / chemically induced; Inflammation / drug therapy; Kidney / chemistry; Lipopolysaccharides / adverse effects; Liver / chemistry; Milk / chemistry; Muscle, Skeletal / chemistry; Sodium Chloride / administration & dosage; Veterinary Drugs / administration & dosage; Veterinary Drugs / pharmacokinetics
Sources: Crossref, Web Of Science
Added: August 6, 2018
2015 conference paper
Flunixin urine residues in culled dairy cows and its relevance to food safety and environmental concern
Presented at the 250th American Chemical Society National Meeting, Boston, MA.
Event: 250th American Chemical Society National Meeting at Boston, MA
Source: NC State University Libraries
Added: February 5, 2022
2015 journal article
Gold and silver nanoparticle interactions with human proteins: impact and implications in biocorona formation
Journal of Materials Chemistry B, 3(10), 2075–2082.
co-author countries:
United States of America 🇺🇸
Contributors: A. Sasidharan *, * & N. Monteiro-Riviere*
Sources: Crossref, ORCID, NC State University Libraries
Added: May 3, 2021
2015 journal article
In vitro safety assessment of food ingredients in canine renal proximal tubule cells
Toxicology in Vitro, 29(2), 289–298.
co-author countries:
United States of America 🇺🇸
Contributors: J. Koči *, B. Jeffery, * & N. Monteiro-Riviere*
author keywords: Food ingredients; Canine; Proximal tubule cells; Lemongrass oil; Gene expression; Metabolic pathway
MeSH headings : Acrolein / analogs & derivatives; Acrolein / toxicity; Aminophenols / toxicity; Animals; Cell Survival / drug effects; Citric Acid / toxicity; Dogs; Eugenol / toxicity; Food Safety; Gene Expression Profiling; Ginger; Guanosine Monophosphate / toxicity; Humans; Inosine Monophosphate / toxicity; Kidney Tubules, Proximal / cytology; Oils, Volatile / toxicity; Plant Extracts / toxicity; Plant Oils / toxicity; Plant Roots; Sorbose / toxicity; Terpenes / toxicity; Thymol / toxicity; Thymus Plant; Toxicity Tests / methods; Xylitol / toxicity
Sources: Crossref, ORCID
Added: May 3, 2021
2015 journal article
Interaction of silver and gold nanoparticles with protein biocorona formation and its impact on cellular toxicity
International Journal of Toxicology, 34, 78–79.
Source: NC State University Libraries
Added: February 5, 2022
2015 journal article
Nanoparticle surface characterization and clustering through concentration-dependent surface adsorption modeling
The Toxicologist, 144, 66.
Source: NC State University Libraries
Added: February 5, 2022
2015 journal article
Pharmacokinetics and pharmacodynamics of gamithromycin in pulmonary epithelial lining fluid in naturally occurring bovine respiratory disease in multisource commingled feedlot cattle
Journal of Veterinary Pharmacology and Therapeutics, 39(2), 157–166.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Anti-Bacterial Agents / metabolism; Anti-Bacterial Agents / pharmacokinetics; Anti-Bacterial Agents / therapeutic use; Area Under Curve; Body Fluids / chemistry; Body Fluids / metabolism; Bovine Respiratory Disease Complex / drug therapy; Bovine Respiratory Disease Complex / metabolism; Cattle; Epithelium / chemistry; Epithelium / metabolism; Lung; Macrolides / metabolism; Macrolides / pharmacokinetics; Macrolides / therapeutic use; Microbial Sensitivity Tests; Models, Biological
Sources: Crossref, Web Of Science
Added: October 2, 2021
2015 journal article
Pharmacokinetics of metallic nanoparticles
WIREs Nanomedicine and Nanobiotechnology, 7(2), 189–217.
co-author countries:
United States of America 🇺🇸
Contributors: Z. Lin *, N. Monteiro-Riviere* & *
MeSH headings : Animals; Humans; Metal Nanoparticles / chemistry; Models, Biological; Pharmacokinetics
Sources: Crossref, ORCID
Added: April 30, 2021
2015 journal article
Predicting Adsorption Affinities of Small Molecules on Carbon Nanotubes Using Molecular Dynamics Simulation
ACS Nano, 9(12), 11761–11774.
co-author countries:
United States of America 🇺🇸
author keywords: nanoparticles; free-energy calculations; surface physicochemistry; virtual screening; benzene derivatives; graphene; surface functionalization; aromatic
Source: Crossref
Added: December 24, 2021
2015 journal article
Predicting the impact of biocorona formation kinetics on interspecies extrapolations of nanoparticle biodistribution modeling
Nanomedicine, 10(1), 25–33.
co-author countries:
United States of America 🇺🇸
Contributors: F. Sahneh *, C. Scoglio *, N. Monteiro-Riviere* & *
author keywords: allometry; biocorona; interspecies extrapolation; in vitro-in vivo correlation; nanomaterials; nanoparticle biodistribution
MeSH headings : Animals; Humans; Kinetics; Mice; Models, Theoretical; Nanoparticles / chemistry; Nanoparticles / therapeutic use; Pharmacokinetics; Rats; Surface Properties; Tissue Distribution
Sources: Crossref, ORCID
Added: April 30, 2021
2015 journal article
Prediction and comparison of size-dependent biodistribution of polyethylene glycol-coated gold nanoparticles in adult mice: a physiologically based pharmacokinetic model
The Toxicologist, 144, 65.
Source: NC State University Libraries
Added: February 5, 2022
2015 journal article
Quantification of vehicle mixture effects on in vitro transdermal chemical flux using a random process diffusion model
Journal of Controlled Release, 217, 74–81.
co-author countries:
United States of America 🇺🇸
author keywords: Transdermal absorption; Chemical mixture; QSPR; Skin permeability; Mathematical modeling; In vitro model
MeSH headings : 1-Octanol / chemistry; Animals; Diffusion; Models, Biological; Molecular Weight; Pharmaceutical Preparations / chemistry; Pharmaceutical Preparations / metabolism; Quantitative Structure-Activity Relationship; Skin / metabolism; Skin Absorption; Swine; Water / chemistry
Sources: Crossref, Web Of Science
Added: August 6, 2018
2015 journal article
Safety assessment of pet food ingredients using cryopreserved canine hepatocytes-based in vitro assays
The Toxicologist, 144, 20.
Source: NC State University Libraries
Added: February 5, 2022
2015 journal article
Safety assessment of potential food ingredients in canine hepatocytes
Food and Chemical Toxicology, 78, 105–115.
co-author countries:
United States of America 🇺🇸
Contributors: L. Zhang *, J. Koci *, B. Jeffery, * & N. Monteiro-Riviere*
MeSH headings : Acetaminophen / toxicity; Acrolein / analogs & derivatives; Acrolein / toxicity; Aflatoxin B1 / toxicity; Animal Feed / standards; Animals; Cell Line; Cell Survival / drug effects; Dogs; Down-Regulation; Eugenol / toxicity; Food Analysis; Food Safety; Ginger / chemistry; Ginger / toxicity; Hepatocytes / drug effects; Hepatocytes / metabolism; Humans; Lethal Dose 50; Oils, Volatile / toxicity; Plant Extracts / toxicity; Plant Oils / toxicity; Plant Roots / chemistry; Plant Roots / toxicity; Rats; Terpenes / toxicity; Thymol / toxicity; Up-Regulation; Xylitol / toxicity
Sources: Crossref, ORCID
Added: April 30, 2021
2015 journal article
Toxicokinetic approaches to improving accuracy of drug withdrawal times in food producing animals to avoid toxic violative tissue residues
International Journal of Toxicology, 34, 78.
Source: NC State University Libraries
Added: February 5, 2022
2014 journal article
A pharmacokinetic modeling framework for interspecies extrapolation of nanoparticle biodistribution taking into account biocorona dynamics independent of species-specific disposition processes
Toxicologist, 138, 211.
Source: NC State University Libraries
Added: May 21, 2022
2014 journal article
Antimicrobial Agents in Veterinary Medicine
Journal of Veterinary Pharmacology and Therapeutics, 37(1), 1–1.
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Bacteria / drug effects; Bacterial Infections / drug therapy; Bacterial Infections / veterinary; Drug Resistance, Bacterial; Drug Utilization / standards
Source: Crossref
Added: December 24, 2021
2014 conference paper
Canine renal proximal tubule cells as an in vitro model for toxicity assessment of pet food ingredients
Central States Society of Toxicology Annual Meeting, 49.
Source: NC State University Libraries
Added: May 27, 2022
2014 chapter
Dermal Exposure and Absorption of Chemicals and Nanomaterials
In Reference Module in Biomedical Sciences.
co-author countries:
United States of America 🇺🇸
Sources: Crossref, ORCID
Added: May 30, 2021
2014 chapter
Dermatoxicity of nanomaterials
In B. Fadeel (Ed.), Handbook of Safety Assessment of Nanomaterials: From Toxicology Testing to Personalized Medicine (pp. 439–459). Singapore: Pan Stanford.
Ed(s): B. Fadeel
Source: NC State University Libraries
Added: May 27, 2022
2014 journal article
Development of a Mixed-Effect Pharmacokinetic Model for Vehicle Modulated In Vitro Transdermal Flux of Topically Applied Penetrants
JOURNAL OF PHARMACEUTICAL SCIENCES, 103(3), 1002–1012.
co-author countries:
United States of America 🇺🇸
author keywords: transdermal drug delivery; skin; passive diffusion; transport; mathematical model; in vitro models; formulation vehicle; diffusion
MeSH headings : Administration, Cutaneous; Algorithms; Animals; Diffusion; Dimethylpolysiloxanes / chemistry; In Vitro Techniques; Models, Biological; Pharmaceutical Preparations / administration & dosage; Pharmaceutical Preparations / analysis; Pharmaceutical Preparations / chemistry; Pharmaceutical Vehicles / chemistry; Pharmacokinetics; Reproducibility of Results; Skin Absorption; Sus scrofa
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Development of a physiologically based pharmacokinetic model for flunixin in cattle (Bos taurus)
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT, 31(9), 1506–1521.
co-author countries:
United States of America 🇺🇸
author keywords: flunixin; PBPK models; withdrawal intervals; route of administration; cattle (Bos taurus)
MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / administration & dosage; Anti-Inflammatory Agents, Non-Steroidal / blood; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Cattle / blood; Clonixin / administration & dosage; Clonixin / analogs & derivatives; Clonixin / blood; Clonixin / pharmacokinetics; Drug Residues; Liver / chemistry; Liver / metabolism; Milk / chemistry; Models, Biological; Sensitivity and Specificity; Software; Uncertainty
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 conference paper
Differential effects of some natural compounds on the transdermal penetration of caffeine and salicylic acid
Central States Society of Toxicology Annual Meeting, 52.
Source: NC State University Libraries
Added: May 27, 2022
2014 conference paper
Impact and implications of gold nanoparticle interactions with human serum proteins and biocorona formation
Central States Society of Toxicology Annual Meeting, 19.
Source: NC State University Libraries
Added: May 27, 2022
2014 chapter
Importance of veterinary drug residues
In R. Baynes & J. E. Riviere (Eds.), Strategies for Reducing Drug and Chemical Residues in Food Animals: International Approaches to Residue Avoidance, Management and Testing (pp. 1–8,). New York: Wiley.
Ed(s): R. Baynes &
Source: NC State University Libraries
Added: May 21, 2022
2014 journal article
In silico models to predict dermal absorption from complex agrochemical formulations
SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 25(7), 565–588.
co-author countries:
Germany 🇩🇪 United States of America 🇺🇸
author keywords: dermal absorption; mixture; quantitative structure permeability relationship (QSPR); risk assessment; agrochemicals
MeSH headings : Agrochemicals / pharmacokinetics; Animals; Complex Mixtures / pharmacokinetics; Computer Simulation; Humans; Linear Models; Models, Biological; Quantitative Structure-Activity Relationship; Rats; Skin / metabolism; Skin Absorption
Source: Web Of Science
Added: August 6, 2018
2014 journal article
In silico models to predict dermal absorption from complex agrochemical formulations
SAR and QSAR in Environmental Research, 6, 1–24.
Source: NC State University Libraries
Added: February 5, 2022
2014 journal article
In vitro safety assessment of pet food ingredients on canine primary renal tubule cell lines
Toxicologist, 138, 81.
Source: NC State University Libraries
Added: May 21, 2022
2014 journal article
Interspecies Mixed-Effect Pharmacokinetic Modeling of Penicillin G in Cattle and Swine
Antimicrobial Agents and Chemotherapy, 58(8), 4495–4503.
co-author countries:
United States of America 🇺🇸
MeSH headings : Age Factors; Animals; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Body Weight; Cattle; Humans; Injections, Intramuscular; Injections, Intravenous; Kidney / chemistry; Kidney / metabolism; Liver / chemistry; Liver / metabolism; Meat / analysis; Models, Statistical; Muscle, Skeletal / chemistry; Muscle, Skeletal / metabolism; Penicillin G / blood; Penicillin G / pharmacokinetics; Species Specificity; Swine
Sources: Crossref, Web Of Science
Added: August 6, 2018
2014 journal article
Interspecies allometric meta-analysis of the comparative pharmacokinetics of 85 drugs across veterinary and laboratory animal species
Journal of Veterinary Pharmacology and Therapeutics, 38(3), 214–226.
co-author countries:
United States of America 🇺🇸
Event: American Conference on Pharmacometrics at Las Vegas, NV
MeSH headings : Animals; Humans; Species Specificity; Veterinary Drugs / administration & dosage; Veterinary Drugs / pharmacokinetics
Sources: Crossref, NC State University Libraries
Added: December 24, 2021
2014 conference paper
Interspecies and in vitro / in vivo extrapolation of nanoparticle biodistribution involving protein corona formation
Proceedings of the 7th International Nanotoxicology Conference, 31.
Event: 7th International Nanotoxicology Conference at Antalya, Turkey
Source: NC State University Libraries
Added: May 21, 2022
2014 journal article
Nanoparticle Surface Characterization and Clustering through Concentration-Dependent Surface Adsorption Modeling
ACS Nano, 8(9), 9446–9456.
co-author countries:
Germany 🇩🇪
Contributors: R. Chen, Y. Zhang, F. Darabi Sahneh, C. Scoglio, W. Wohlleben *, A. Haase *, N. Monteiro-Riviere* , *
author keywords: BSAI; nanoparticles; nanomedicine; nanotoxicology surface physicochemistry; in situ characterization
MeSH headings : Adsorption; Models, Molecular; Nanoparticles / chemistry; Surface Properties
Sources: Crossref, ORCID
Added: June 12, 2021
2014 conference paper
Nanoparticle surface characterization and clustering through concentration-dependent surface adsorption modeling
Central States Society of Toxicology Annual Meeting, 46.
Source: NC State University Libraries
Added: May 27, 2022
2014 chapter
Pharmacokinetics and biodistribution of nanomaterials
In N. A. Monteiro-Riviere & C. L. Tran (Eds.), Nanotoxicology (2nd ed., pp. 135–152). New York: Informa.
Ed(s): N. Monteiro-Riviere & C. Tran
Source: NC State University Libraries
Added: May 27, 2022
2014 conference paper
Pharmacokinetics and pharmacodynamics of gamithromycin in pulmonary epithelial lining fluid 9PLF) in naturally occurring bovine respiratory disease in multi-sourced commingled feedlot cattle
Presented at the 7th International Conference on Antimicrobial Agents in Veterinary Medicine, Berlin, Germany.
Event: 7th International Conference on Antimicrobial Agents in Veterinary Medicine at Berlin, Germany
Source: NC State University Libraries
Added: May 21, 2022
2014 journal article
Pharmacokinetics, tissue distribution, and excretion of nomegestrol acetate in female rats
European Journal of Drug Metabolism and Pharmacokinetics, 40(4), 435–442.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: Nomegestrol acetate; NOMAC; Pharmacokinetics; Tissue distribution; Excretion; HPLC
MeSH headings : Animals; Bile / drug effects; Bile / metabolism; Feces; Female; Liver / drug effects; Liver / metabolism; Megestrol / pharmacokinetics; Megestrol / urine; Norpregnadienes / pharmacokinetics; Norpregnadienes / urine; Rats; Rats, Sprague-Dawley; Tissue Distribution / drug effects; Tissue Distribution / physiology
Source: Crossref
Added: December 24, 2021
2014 chapter
Physiologically based nanomaterial pharmacokinetic (PBNK) models
In B. Fadeel (Ed.), Handbook of Safety Assessment of Nanomaterials: From Toxicology Testing to Personalized Medicine (pp. 243–264). Singapore: Pan Stanford.
Ed(s): B. Fadeel
Source: NC State University Libraries
Added: May 27, 2022
2014 conference paper
Prediction and comparison of size-dependent biodistribution of polyethylene glycol-coated gold nanoparticles in adult mice: a physiologically based pharmacokinetic model
Central States Society of Toxicology Annual Meeting, 50.
Source: NC State University Libraries
Added: May 27, 2022
2014 journal article
Prediction of formulation effects on dermal absorption of topically applied ectoparasiticides dosed in vitro on canine and porcine skin using a mixture-adjusted quantitative structure permeability relationship
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 37(5), 435–444.
co-author countries:
United States of America 🇺🇸
MeSH headings : Administration, Topical; Animals; Chemical Phenomena; Dogs; Insecticides / pharmacokinetics; Models, Biological; Permeability; Skin / drug effects; Skin Absorption / physiology; Swine; Tissue Culture Techniques
Source: Web Of Science
Added: August 6, 2018
2014 chapter
Risk management of chemical contaminants in livestock
In R. Baynes & J. E. Riviere (Eds.), Strategies for Reducing Drug and Chemical Residues in Food Animals: International Approaches to Residue Avoidance, Management and Testing (pp. 303–312). New York: Wiley.
Ed(s): R. Baynes &
Source: NC State University Libraries
Added: May 21, 2022
2014 conference paper
Safety assessment of pet food ingredients using cryopreserved canine hepatocytes-based in vitro assays
Central States Society of Toxicology, 47.
Event: Central States Society of Toxicology
Source: NC State University Libraries
Added: May 21, 2022
2014 journal article
Safety assessment of potential food ingredients on canine primary hepatocytes
Toxicologist, 138, 420.
Source: NC State University Libraries
Added: May 21, 2022
2014 conference paper
Silver and gold metal nanoparticle-protein interactions: Role of physiochemical properties
Proceedings of the 7th International Nanotoxicology Conference, 245–246.
Event: 7th International Nanotoxicology Conference at Antalya, Turkey
Source: NC State University Libraries
Added: May 21, 2022
2014 chapter
The Food Animal Residue Avoidance databank: An example of risk management of veterinary drug residues
In R. Baynes & J. E. Riviere (Eds.), Strategies for Reducing Drug and Chemical Residues in Food Animals: International Approaches to Residue Avoidance, Management and Testing (pp. 289–302). New York: Wiley.
Ed(s): R. Baynes &
Source: NC State University Libraries
Added: May 21, 2022
2014 journal article
The application of allometric scaling principles to predict pharmacokinetic parameters across species
Expert Opinion on Drug Metabolism & Toxicology, 10(9), 1241–1253.
author keywords: allometric scaling; clearance; comparative pharmacology; elimination half-life; interspecies pharmacokinetics; veterinary medicine; volume of distribution
MeSH headings : Animals; Dose-Response Relationship, Drug; Humans; Models, Theoretical; Pharmaceutical Preparations / administration & dosage; Pharmaceutical Preparations / metabolism; Pharmacokinetics; Species Specificity; Veterinary Drugs / administration & dosage; Veterinary Drugs / pharmacokinetics
Source: Crossref
Added: December 24, 2021
2014 conference paper
Toxicological effect of a pet food ingredient on canine bone marrow derived mesenchymal stem cells and enterocyte-like cells
Central States Society of Toxicology Annual Meeting, 53.
Source: NC State University Libraries
Added: May 27, 2022
2014 journal article
Understanding the dynamic behavior of the protein corona and its influence on the physiochemical composition of silver nanoparticles
Toxicologist, 138, 211.
Source: NC State University Libraries
Added: May 21, 2022
2013 journal article
A dynamically integrative PKPD model to predict the efficacy of marbofloxacin treatment regimen for bovine Manheima hemolytica infection
PAGE, 22, 153,
Source: NC State University Libraries
Added: July 29, 2022
2013 journal article
Animal Health Modeling and Simulation Society (AHM&S): A new society promoting model-based approaches for a better integration and understanding of quantitative pharmacology in veterinary science
PAGE, 22, 143,
Source: NC State University Libraries
Added: June 17, 2022
2013 journal article
Animal Health Modeling and Simulation Society (AHM&S): A new society promoting model-based approaches in veterinary pharmacology
Journal of Veterinary Pharmacology and Therapeutics, 36, 417–419.
Source: NC State University Libraries
Added: May 27, 2022
2013 journal article
Assessing vehicle effects on skin absorption of non-volatile compounds using membrane-coated fiber arrays
Cutaneous and Ocular Toxicology, 32(4), 283–289.
co-author countries:
United States of America 🇺🇸
author keywords: Absorption; chemical mixtures; membrane-coated fiber; skin
MeSH headings : Acrylic Resins / chemistry; Caffeine / chemistry; Cortisone / chemistry; Diclofenac / chemistry; Dimethylpolysiloxanes / chemistry; Ethanol / chemistry; Mannitol / chemistry; Membranes, Artificial; Polyethylene Glycols / chemistry; Salicylic Acid / chemistry; Skin Absorption; Testosterone / chemistry; Volatilization; Water / chemistry
Source: Crossref
Added: December 24, 2021
2013 journal article
Assessing vehicle effects on skin absorption using artificial membrane assays
European Journal of Pharmaceutical Sciences, 50(5), 569–576.
co-author countries:
United States of America 🇺🇸
author keywords: Skin; Parallel artificial membrane permeability assays (PAMPAS); Isopropyl myristate; Certramides; Strat-M (TM); Dermal/percutaneous absorption
MeSH headings : Animals; Biological Assay; Caffeine / chemistry; Caffeine / metabolism; Cortisone / chemistry; Cortisone / metabolism; Diclofenac / chemistry; Diclofenac / metabolism; Ethanol / chemistry; In Vitro Techniques; Mannitol / chemistry; Mannitol / metabolism; Membranes, Artificial; Propylene Glycol / chemistry; Quantitative Structure-Activity Relationship; Salicylic Acid / chemistry; Salicylic Acid / metabolism; Skin / metabolism; Skin Absorption; Swine; Testosterone / chemistry; Testosterone / metabolism; Water / chemistry
Source: Crossref
Added: December 24, 2021
2013 conference paper
Assessment of drug-vehicle interactions seen in topical delivery using three PAMPA artificial membrane systems.
Riviere, J. E., & Karadzovska, D. (2013, July 21). Presented at the 40th Annual Meeting & Exposition of the Controlled Release Society.
Event: 40th Annual Meeting & Exposition of the Controlled Release Society on July 21-24, 2013
Source: NC State University Libraries
Added: June 17, 2022
2013 journal article
Biological Surface Adsorption Index (BSAI): A molecular signature for nanomaterial interactions
Toxicologist, 132, 517.
Source: NC State University Libraries
Added: May 27, 2022
2013 conference paper
Comparison of ELISA and LC MS/MS for the measurement of flunixin plasma concentration in beef cattle after intravenous and subcutaneous administration
Shelver, W. L., Tell, L. A., Wagner, S., Wetzlich, S. E., Baynes, R. E., & Riviere, J. E. (2013, August 25). Presented at the 127th AOAC Annual Meeting & Exposition, Chicago, IL.
Event: 127th AOAC Annual Meeting & Exposition at Chicago, IL on August 25-28, 2013
Source: NC State University Libraries
Added: June 17, 2022
2013 journal article
Comparison of ELISA and LC-MS/MS for the Measurement of Flunixin Plasma Concentrations in Beef Cattle after Intravenous and Subcutaneous Administration
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 61(11), 2679–2686.
co-author countries:
United States of America 🇺🇸
author keywords: cattle; flunixin; ELISA; pharmacokinetics; elimination; administration; concentration
MeSH headings : Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal / administration & dosage; Anti-Inflammatory Agents, Non-Steroidal / blood; Cattle; Chromatography, High Pressure Liquid / methods; Clonixin / administration & dosage; Clonixin / analogs & derivatives; Clonixin / blood; Enzyme-Linked Immunosorbent Assay / methods; Injections, Intravenous; Tandem Mass Spectrometry / methods; Veterinary Drugs / administration & dosage; Veterinary Drugs / blood
Source: Web Of Science
Added: August 6, 2018
2013 conference paper
Comparison of flunixin pharmacokinetic and milk elimination in healthy cows and cows with mastitis
Proceedings of the 18th American Academy of Veterinary Pharmacology and Therapeutics Biennial Symposium. Presented at the 18th American Academy of Veterinary Pharmacology and Therapeutics Biennial Symposium, Potomac, MD.
Event: 18th American Academy of Veterinary Pharmacology and Therapeutics Biennial Symposium at Potomac, MD
Source: NC State University Libraries
Added: May 27, 2022
2013 journal article
Computational approaches and metrics needed for formulating biologically realistic nanomaterial pharmacokinetic models
Computational Science & Discovery, 6(1).
Source: NC State University Libraries
Added: June 3, 2022
2013 report
Developing a global curriculum for regulators
[Discussion Paper]. https://nam.edu/wp-content/uploads/2015/06/BGH-GlobalCurriculum.pdf
Source: NC State University Libraries
Added: June 3, 2022
2013 journal article
Dynamics of nanoparticle-protein corona complex. Analytical results from population balance equations
PlosOne, 8, 64690.
co-author countries:
United States of America 🇺🇸
MeSH headings : Humans; Kinetics; Models, Statistical; Nanoparticles / chemistry; Nonlinear Dynamics; Particle Size; Protein Binding; Proteins / chemistry; Surface Properties
Source: Web Of Science
Added: May 27, 2022
2013 journal article
FARAD Digest: Effects of new sampling protocols on procaine penicillin G withdrawal intervals for cattle
Journal of the American Veterinary Medical Association, 243(10), 1408–1412,
Source: NC State University Libraries
Added: June 3, 2022
2013 conference paper
Food Safety: The interaction of pharmacometrics and veterinary medicine
Population Approach Group in Europe (PAGE) 2013 meeting, 20–21.
Source: NC State University Libraries
Added: May 27, 2022
2013 conference paper
Impact of nanoparticle protein corona on assessing in vitro cellular uptake of silver nanoparticles into human epidermal keratinocytes. 40th Annual Mtg
Monteiro-Riviere, N. A., Samberg, M., Oldenburg, S., & Riviere, J. E. (2013, July 21). Presented at the 40th Annual Meeting & Exposition of the Controlled Release Society, Honolulu, Hawaii.
Event: 40th Annual Meeting & Exposition of the Controlled Release Society at Honolulu, Hawaii on July 21-24, 2013
Source: NC State University Libraries
Added: June 17, 2022
2013 conference paper
In silico models for dermal absorption from complex formulations
Guth, K., Riviere, J., Brooks, J., Schafer-Korting, M., Dammann, M., Fabian, E., … Landsiedel, R. (2013, September). Presented at the 15th Congress of European Society for Alternatives to Animal Testing (EUSAAT), Linz, Austria.
Event: 15th Congress of European Society for Alternatives to Animal Testing (EUSAAT) at Linz, Austria
Source: NC State University Libraries
Added: May 27, 2022
2013 journal article
In silico models for dermal absorption from complex formulations
Naunyn-Schmiedelberg’s Archives of Pharmacology, 386, 29.
Source: NC State University Libraries
Added: May 27, 2022
2013 journal article
Limitations of MIC as the sole criterion in antimicrobial drug dosage regimen design: The need for full characterization of antimicrobial pharmacodynamic profile especially for drug-resistant organisms
The Veterinary Journal, 198(1), 15–18.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Anti-Infective Agents / administration & dosage; Anti-Infective Agents / pharmacokinetics; Anti-Infective Agents / pharmacology; Bacteria / drug effects; Drug Resistance, Bacterial; Microbial Sensitivity Tests / methods; Microbial Sensitivity Tests / veterinary; Models, Biological
Source: Crossref
Added: December 24, 2021
2013 journal article
Modeling the effect of experimental variables on the in vitro permeation of six model compounds across porcine skin
International Journal of Pharmaceutics, 443(1-2), 58–67.
co-author countries:
United States of America 🇺🇸
author keywords: Quantitative structure-permeability; relationships (QSPeRs); Experimental variables; Mixture factor; Steady-state flux; Percutaneous absorption
MeSH headings : Animals; Drug Carriers; Female; Hydrogen Bonding; In Vitro Techniques; Models, Biological; Permeability; Pharmaceutical Preparations / administration & dosage; Pharmaceutical Preparations / metabolism; Quantitative Structure-Activity Relationship; Regression Analysis; Skin / metabolism; Skin Absorption; Swine
Sources: Crossref, Web Of Science
Added: August 6, 2018
2013 conference paper
Nanomaterial pharmacokinetics and biodistribution: Can in vitro data quantitatively predict in vivo?
Riviere, J. E., & Monteiro-Riviere, N. A. (2013, October 28). Presented at the 6th International Symposium on Nanotechnology, Occupational and Environmental Health., Nagoya, Japan.
Event: 6th International Symposium on Nanotechnology, Occupational and Environmental Health. at Nagoya, Japan on October 28-31, 2013
Source: NC State University Libraries
Added: June 17, 2022
2013 journal article
Occurrence of flunixin residues in bovine milk samples from the USA
Food Additives & Contaminants: Part A, 30(9), 1513–1516.
co-author countries:
United States of America 🇺🇸
author keywords: flunixin; milk residues; UPLC-MS; CHARM((R)); milk; food safety
MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / metabolism; Cattle; Chromatography, High Pressure Liquid; Clonixin / analogs & derivatives; Clonixin / analysis; Clonixin / metabolism; Dairying / legislation & jurisprudence; Drug Residues / analysis; Enzyme-Linked Immunosorbent Assay; Food Contamination / legislation & jurisprudence; Food Handling; Food Inspection / legislation & jurisprudence; Guideline Adherence; Legislation, Food; Milk / chemistry; Milk / standards; Spectrometry, Mass, Electrospray Ionization; Transportation; United States; United States Department of Agriculture; United States Food and Drug Administration
Sources: Crossref, Web Of Science, ORCID
Added: August 6, 2018
2013 journal article
Of mice, men and nanoparticle biocoronas: are in vitro to in vivo correlations and interspecies extrapolations realistic?
Nanomedicine, 8(9), 1357–1359.
co-author countries:
United States of America 🇺🇸
author keywords: biocorona; biodistribution; in vitro-in vivo correlation; interspecies extrapolation; nanoparticle; pharmacokinetics; protein corona
MeSH headings : Drug Delivery Systems; Humans; Lipids / administration & dosage; Lipids / chemistry; Nanoparticles / administration & dosage; Nanoparticles / chemistry; RNA, Small Interfering / administration & dosage; RNA, Small Interfering / chemistry
Source: Crossref
Added: December 24, 2021
2013 journal article
Oxidative Stress and Dermal Toxicity of Iron Oxide Nanoparticles In Vitro
CELL BIOCHEMISTRY AND BIOPHYSICS, 67(2), 461–476.
co-author countries:
Sweden 🇸🇪 United States of America 🇺🇸
Contributors: A. Murray*, E. Kisin*, A. Inman n, S. Young*, M. Muhammed*, T. Burks*, A. Uheida*, A. Tkach*
author keywords: Nanoparticles; Skin exposure; Ultraviolet radiation; Iron oxide
MeSH headings : Biological Transport; Cell Survival / drug effects; Cytokines / metabolism; Glutathione / metabolism; Humans; Keratinocytes / cytology; Keratinocytes / drug effects; Keratinocytes / metabolism; L-Lactate Dehydrogenase / metabolism; Magnetite Nanoparticles / chemistry; Magnetite Nanoparticles / toxicity; NF-kappa B / metabolism; Oxidative Stress / drug effects; Particle Size; Skin / cytology; Skin / drug effects; Transcription Factor AP-1 / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018
2013 review
Predicting skin permeability from complex vehicles
[Review of ]. ADVANCED DRUG DELIVERY REVIEWS, 65(2), 265–277.
co-author countries:
United States of America 🇺🇸
Contributors: D. Karadzovska n, J. Brooks n, N. Monteiro-Riviere n & n
author keywords: Chemical mixtures; Formulations; Percutaneous/dermal absorption; Quantitative structure-permeation relationship (QSPR); QSAR; Linear free energy relationships (LFER); Mixture factor; Topical drug delivery enhancers
MeSH headings : Animals; Drug Delivery Systems; Humans; Linear Energy Transfer; Models, Theoretical; Permeability; Pharmaceutical Preparations / administration & dosage; Pharmaceutical Preparations / metabolism; Pharmaceutical Vehicles / chemistry; Quantitative Structure-Activity Relationship; Skin / metabolism; Skin Absorption
Sources: Web Of Science, ORCID
Added: August 6, 2018
2013 journal article
Prediction of flunixin tissue residue concentrations in livers from diseased cattle
Food and Chemical Toxicology, 62, 876–879.
author keywords: Flunixin; Population pharmacokinetics; Tissue residue; Monte Carlo simulation
Sources: Crossref, Web Of Science
Added: August 6, 2018
2013 journal article
Protein binding effects cellular uptake of silver nanoparticles in human cells
Toxicologist, 132, 283–284.
Source: NC State University Libraries
Added: May 27, 2022
2013 journal article
Protein binding modulates the cellular uptake of silver nanoparticles into human cells: Implications for in vitro to in vivo extrapolations?
TOXICOLOGY LETTERS, 220(3), 286–293.
Contributors: N. Monteiro-Riviere* , M. Samberg*, S. Oldenburg & *
author keywords: Protein corona; Protein binding of nanoparticles; Cellular uptake of silver nanoparticles; Albumin cell uptake; Transferrin cell uptake; IgG cell uptake
MeSH headings : Humans; Immunoglobulin G / metabolism; Keratinocytes / metabolism; Metal Nanoparticles / chemistry; Microscopy, Electron, Transmission; Protein Binding; Serum Albumin / metabolism; Silver / metabolism; Transferrin / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018
2013 conference paper
Protein corona effects silver nanoparticle uptake in human cells
Presented at the 4th Annual Nanofronteirs Symposium, Columbia, MO.
Event: 4th Annual Nanofronteirs Symposium at Columbia, MO
Source: NC State University Libraries
Added: June 17, 2022
2013 conference paper
Skin exposure to nanomaterials: Should we be concerned?
The 6th International Symposium on Nanotechnology, Occupational and Environmental Health, 48. Nagoya, Japan.
Source: NC State University Libraries
Added: May 27, 2022
2013 journal article
Solubility criteria for veterinary drugs: Workshop report
Pharm. Forum, 39(3).
Source: NC State University Libraries
Added: May 27, 2022
2013 conference paper
The application of modeling and simulation for animal health (therapeutics): Gaps, challenges and opportunities
Proceedings of the 18th American Academy of Veterinary Pharmacology and Therapeutics Biennial Symposium. Presented at the 18th American Academy of Veterinary Pharmacology and Therapeutics Biennial Symposium, Potomac, MD.
Event: 18th American Academy of Veterinary Pharmacology and Therapeutics Biennial Symposium at Potomac, MD
Source: NC State University Libraries
Added: May 27, 2022
2013 chapter
Transforming the animal health regulatory system for the 21st century. The Institute of Computational Comparative Medicine and the Animal Health Regulatory Science Initiative
In Proceedings One Hundred and Seventeenth Annual Meeting of the United States Animal Health Association (p. 136). https://www.usaha.org/upload/Proceedings/USAHAProceedings-2013-117th.pdf
Event: 107th Annual Meeting of the United States Animal Health Association at San Diego, CA on October 17-23, 2013
Source: NC State University Libraries
Added: June 17, 2022
2013 journal article
Use of population pharmacokinetic modeling and Monte Carlo simulation to capture individual animal variability in the prediction of flunixin withdrawal times in cattle
Journal of Veterinary Pharmacology and Therapeutics, 36(3), 248–257.
co-author countries:
United States of America 🇺🇸
MeSH headings : Algorithms; Animals; Anti-Inflammatory Agents, Non-Steroidal / administration & dosage; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Cattle / blood; Clonixin / administration & dosage; Clonixin / analogs & derivatives; Clonixin / pharmacokinetics; Computer Simulation; Drug Administration Routes; Drug Residues / pharmacokinetics; Female; Liver / metabolism; Male; Models, Biological; Monte Carlo Method
Sources: Crossref, Web Of Science, ORCID
Added: August 6, 2018
2013 journal article
Vasomodulation Influences on the Transdermal Delivery of Ibuprofen
Journal of Pharmaceutical Sciences, 102(11), 4072–4078.
co-author countries:
United States of America 🇺🇸
author keywords: transdermal delivery; ibuprofen; vasodilation; blood flow; skin; permeation enhancer; formulation vehicle; pharmacokinetics
MeSH headings : Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal / administration & dosage; Anti-Inflammatory Agents, Non-Steroidal / blood; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Ibuprofen / administration & dosage; Ibuprofen / blood; Ibuprofen / pharmacokinetics; Papaverine / pharmacology; Permeability / drug effects; Rabbits; Skin / drug effects; Skin / metabolism; Skin Absorption / drug effects; Tolazoline / administration & dosage; Tolazoline / pharmacology; Vasodilator Agents / administration & dosage; Vasodilator Agents / pharmacology
Source: Crossref
Added: December 24, 2021
2013 journal article
What to do about unsafe medicines?
British Medical Journal, 347, 5064,
co-author countries:
United States of America 🇺🇸
MeSH headings : Drug Industry / legislation & jurisprudence; Drug Industry / standards; Female; Humans; Male; Patient Education as Topic; Patient Safety / legislation & jurisprudence; Prescription Drugs / standards; Quality Assurance, Health Care
Source: Web Of Science
Added: May 27, 2022
2012 journal article
A Novel Long-Acting Transdermal Fentanyl Solution for Dogs
Journal of Veterinary Pharmacology and Therapeutics, 35(Supplement 2), 1.
Ed(s):
Source: NC State University Libraries
Added: June 17, 2022
2012 chapter
Absorption
In E. Hodgson (Ed.), Pesticide Biotransformation and Disposition (pp. 25–52). New York: Elsevier.
Ed(s): E. Hodgson
Source: NC State University Libraries
Added: June 17, 2022
2012 journal article
Acute vascular effects of nanoparticle infusion in isolated perfused skin
Nanomedicine: Nanotechnology, Biology and Medicine, 8(4), 428–431.
co-author countries:
United States of America 🇺🇸
Contributors: n, T. Leavens n , J. Brooks n & N. Monteiro-Riviere n
author keywords: Nanoparticles; Vascular toxicity; In vitro; Biodistribution
MeSH headings : Animals; Female; Perfusion; Quantum Dots; Skin / blood supply; Skin / pathology; Skin / physiopathology; Sus scrofa; Vascular Resistance / drug effects
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018
2012 journal article
Acute vascular effects of nanoparticle infusion in isolated perfused skin
[Poster]. Toxicologist, 126, 18. https://www.toxicology.org/pubs/docs/Tox/2012Tox.pdf
Event: 51st Annual Meeting and ToxExpo at San Francisco, CA on March 11-15, 2012
Source: NC State University Libraries
Added: June 17, 2022
2012 journal article
Challenges obtaining a biowaiver for topical veterinary dosage forms
Journal of Veterinary Pharmacology and Therapeutics, 35(SUPPL. 1), 103–114.
co-author countries:
Switzerland 🇨🇭 France 🇫🇷 United States of America 🇺🇸
Contributors: R. Baynes n, n, T. Franz, N. Monteiro-Riviere n , P. Lehman, M. Peyrou *, P. Toutain *
MeSH headings : Administration, Topical; Animals; Dosage Forms; Drug Administration Routes; Legislation, Drug; Species Specificity; Therapeutic Equivalency; Veterinary Drugs / administration & dosage; Veterinary Drugs / chemistry; Veterinary Drugs / pharmacokinetics
Sources: Crossref, Web Of Science, ORCID
Added: August 6, 2018
2012 chapter
Dermal Toxicity
In R. Gupta (Ed.), Veterinary Toxicology: Basic and Clinical Principles (2nd ed., pp. 337–350,). New York: Elsevier.
Ed(s): R. Gupta
Source: NC State University Libraries
Added: June 17, 2022
2012 journal article
Development of a physiologically based pharmacokinetic model to predict tulathromycin distribution in goats
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 35(2), 121–131.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Computer Simulation; Disaccharides / blood; Disaccharides / pharmacokinetics; Goats / blood; Goats / metabolism; Heterocyclic Compounds / blood; Heterocyclic Compounds / pharmacokinetics; Models, Biological; Sensitivity and Specificity; Software; Tissue Distribution
Sources: Web Of Science, ORCID
Added: August 6, 2018
2012 chapter
Distribution and Pharmacokinetic Models
In E. Hodgson (Ed.), Pesticide Biotransformation and Disposition (pp. 117–148). New York: Elsevier.
Ed(s): E. Hodgson
Source: NC State University Libraries
Added: June 17, 2022
2012 journal article
Effect of eight different nanoparticles of different sizes and shapes on human epidermal keratinocytes
[Conference abstract]. Journal of Investigative Dermatology, 132(S1), S52.
Source: NC State University Libraries
Added: June 17, 2022
2012 book
Ensuring Safe Foods and Medical Products through Strong Regulatory Systems Abroad
https://nap.nationalacademies.org/catalog/13296/ensuring-safe-foods-and-medical-products-through-stronger-regulatory-systems-abroad
Ed(s): & G. Buckley
Source: NC State University Libraries
Added: June 17, 2022
2012 journal article
Evaluation of factors important in modeling plasma concentrations of tetracycline hydrochloride administered in water in swine
AMERICAN JOURNAL OF VETERINARY RESEARCH, 73(10), 1641–1649.
Sources: Web Of Science, ORCID
Added: August 6, 2018
2012 journal article
Experimental factors affecting in vitro absorption of six model compounds across porcine skin
Toxicology in Vitro, 26(7), 1191–1198.
author keywords: Dermal absorption/penetration; Diffusion cells; Saturated; Unsaturated; Finite; Infinite; Albumin
MeSH headings : Administration, Cutaneous; Animals; Cattle; Diffusion; Female; In Vitro Techniques; Models, Biological; Permeability / drug effects; Serum Albumin, Bovine / metabolism; Skin / drug effects; Skin / metabolism; Skin Absorption; Swine; Xenobiotics / administration & dosage; Xenobiotics / pharmacokinetics
Sources: Crossref, Web Of Science
Added: August 6, 2018
2012 journal article
In vitro biodistribution of silver nanoparticles in isolated perfused porcine skin flaps
JOURNAL OF APPLIED TOXICOLOGY, 32(11), 913–919.
co-author countries:
United States of America 🇺🇸
Contributors: T. Leavens n , N. Monteiro-Riviere n , A. Inman n, J. Brooks n, S. Oldenburg* & n
author keywords: silver nanoparticles; biodistribution; skin
MeSH headings : Animals; Metal Nanoparticles / chemistry; Nanoparticles / chemistry; Perfusion; Silver / chemistry; Silver / pharmacokinetics; Skin / metabolism; Swine / metabolism; Tissue Distribution
Sources: Web Of Science, ORCID
Added: August 6, 2018
2012 conference paper
In vitro biodistribution of silver nanoparticles in isolated perfused porcine skin flaps
[Poster]. Toxicologist, 126, 17. https://www.toxicology.org/pubs/docs/Tox/2012Tox.pdf
Event: 51st Annual Meeting and ToxExpo at San Francisco, CA on March 11-15, 2012
Source: NC State University Libraries
Added: June 17, 2022
2012 journal article
LACK OF HYDROXYLATED FULLERENE TOXICITY AFTER INTRAVENOUS ADMINISTRATION TO FEMALE SPRAGUE-DAWLEY RATS
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 75(7), 367–373.
co-author countries:
United States of America 🇺🇸
Contributors: N. Monteiro-Riviere n , K. Linder n, A. Inman n, J. Saathoff n, X. Xia n & n
MeSH headings : Animals; Blood Chemical Analysis; Drug Administration Schedule; Female; Fullerenes / administration & dosage; Fullerenes / chemistry; Fullerenes / toxicity; Injections, Intravenous; Liver / drug effects; Lymphocytes / drug effects; Nanoparticles / administration & dosage; Nanoparticles / chemistry; Nanoparticles / toxicity; Rats; Rats, Sprague-Dawley; Thymus Gland / drug effects; Toxicity Tests, Acute; Urinalysis
Sources: Web Of Science, ORCID
Added: August 6, 2018
2012 conference paper
Mapping the surface adsorption forces of nanomaterials in biological systems
Presented at the NIEHS Nanotechnology Health Implications Research Consortium Meeting, Research Triangle Park, NC.
Event: NIEHS Nanotechnology Health Implications Research Consortium Meeting at Research Triangle Park, NC on January 26-27, 2012
Source: NC State University Libraries
Added: July 29, 2022
2012 chapter
Nanoscale feed ingredients and animal and human health
In J. Fink-Gremmels (Ed.), Animal feed contamination : effects on livestock and food safety (pp. 540–553). Philadelphia, PA: Woodhead Publishing.
Ed(s): J. Fink-Gremmels
Source: NC State University Libraries
Added: June 17, 2022
2012 conference paper
Pharmacokinetics and milk elimination of flunixin in dairy cattle following different routes of administration
Waltman, L., Smith, G. W., Leavens, T. L., Baynes, R. E., & Riviere, J. E. (2012, June 3). Abstract presented at the 27th World Buiatrics Congress, Lisbon, Portugal.
Event: 27th World Buiatrics Congress at Lisbon, Portugal on June 3-8, 2012
Source: NC State University Libraries
Added: June 17, 2022
2012 journal article
Pharmacokinetics and tissue elimination of tulathromycin following subcutaneous administration in meat goats
AMERICAN JOURNAL OF VETERINARY RESEARCH, 73(10), 1634–1640.
MeSH headings : Animals; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Disaccharides / blood; Disaccharides / pharmacokinetics; Female; Goats / blood; Goats / metabolism; Heterocyclic Compounds / blood; Heterocyclic Compounds / pharmacokinetics; Injections, Subcutaneous / veterinary; Male; Tandem Mass Spectrometry / veterinary; Time Factors; Tissue Distribution
Sources: Web Of Science, ORCID
Added: August 6, 2018
2012 conference paper
Pharmacokinetics and tissue elimination of tulathromycin following subcutaneous administration in meat goats
Smith, G. W., Romanet, J. L., Leavens, T. L., Tell, L. A., Baynes, R. E., & Riviere, J. E. (2012, June). Abstract presented at the 27th World Buiatrics Congress, Lisbon, Portugal.
Event: 27th World Buiatrics Congress at Lisbon, Portugal on June 3-8, 2012
Source: NC State University Libraries
Added: June 17, 2022
2012 journal article
Plasma pharmacokinetics and milk residues of flunixin and 5-hydroxy flunixin following different routes of administration in dairy cattle
Journal of Dairy Science, 95(12), 7151–7157.
co-author countries:
United States of America 🇺🇸
author keywords: flunixin; residue; pharmacology
MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / administration & dosage; Anti-Inflammatory Agents, Non-Steroidal / analysis; Anti-Inflammatory Agents, Non-Steroidal / blood; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Cattle; Clonixin / administration & dosage; Clonixin / analogs & derivatives; Clonixin / analysis; Clonixin / blood; Clonixin / pharmacokinetics; Drug Residues / analysis; Female; Injections, Intramuscular / veterinary; Injections, Intravenous / veterinary; Injections, Subcutaneous / veterinary; Milk / chemistry
Sources: Crossref, ORCID
Added: January 5, 2020
2012 chapter
Potential Health Risks of Nanoparticles
In Q. Huang (Ed.), Nanotechnology in the Food, Beverage and Nutraceutical Industries (pp. 40–55). Cambridge: Woodhead Publishing.
Ed(s): Q. Huang
Source: NC State University Libraries
Added: June 17, 2022
2012 journal article
Quantum dot penetration into viable human skin
NANOTOXICOLOGY, 6(2), 173–185.
co-author countries:
Australia 🇦🇺 China 🇨🇳 France 🇫🇷 United States of America 🇺🇸
Contributors: T. Prow *, N. Monteiro-Riviere n , A. Inman n, J. Grice *, X. Chen *, X. Zhao *, W. Sanchez*, A. Gierden*
author keywords: Nanoparticles; exposure; nanotoxicology; surface chemistry
MeSH headings : Diffusion Chambers, Culture; Female; Humans; Hydrogen-Ion Concentration; Microscopy, Confocal; Nanoparticles; Particle Size; Polyethylene Glycols / metabolism; Polyethylene Glycols / pharmacology; Quantum Dots; Skin / chemistry; Skin / drug effects; Skin / metabolism; Skin Absorption / drug effects; Tissue Culture Techniques
Sources: Web Of Science, ORCID
Added: August 6, 2018
2012 journal article
Solubility criteria for veterinary drugs
Pharmacopeial Forum, 38(4), 44–54. https://www.usp.org/sites/default/files/usp/document/our-work/chemical-medicines/pf39-4_vet.pdf
Source: NC State University Libraries
Added: June 17, 2022
2012 journal article
The effect of formulations and experimental conditions on in vitro human skin permeation—Data from updated EDETOX database
International Journal of Pharmaceutics, 434(1-2), 280–291.
co-author countries:
United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: QSAR; Skin; Dermal; Permeation; Absorption; In vitro; Decision tree; Finite dosing; Occlusion; Hydration
MeSH headings : Data Mining; Databases, Factual; Humans; Models, Biological; Models, Statistical; Permeability; Pharmaceutical Preparations / administration & dosage; Pharmaceutical Preparations / chemistry; Pharmaceutical Preparations / metabolism; Quantitative Structure-Activity Relationship; Skin / metabolism; Skin Absorption
Sources: Web Of Science, Crossref
Added: August 6, 2018
2012 conference paper
Toxicity assessment of citrate biopure silver and silica-coated silver in human skin cells
Toxicologist, 126, 146. https://www.toxicology.org/pubs/docs/Tox/2012Tox.pdf
Event: 51st Annual Meeting and ToxExpo at San Francisco, CA on March 11-15, 2012
Source: NC State University Libraries
Added: June 17, 2022
2012 conference paper
Toxicity assessment of eight nanoparticles in human epidermal keratinocytes
[Poster]. Toxicologist, 126, 146. https://www.toxicology.org/pubs/docs/Tox/2012Tox.pdf
Event: 51st Annual Meeting and ToxExpo at San Francisco, CA on March 11-15, 2012
Source: NC State University Libraries
Added: June 17, 2022
2012 journal article
Tulathromycin assay validation and tissue residues after single and multiple subcutaneous injections in domestic goats (Capra aegagrus hircus)
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 35(2), 113–120.
co-author countries:
United States of America 🇺🇸
MeSH headings : Adipose Tissue; Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Disaccharides / administration & dosage; Disaccharides / blood; Disaccharides / pharmacokinetics; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Residues; Female; Goats / metabolism; Heterocyclic Compounds / administration & dosage; Heterocyclic Compounds / blood; Heterocyclic Compounds / pharmacokinetics; Infusions, Subcutaneous; Kidney; Liver; Lung; Male; Muscle, Skeletal; Reproducibility of Results; Tissue Distribution
Sources: Web Of Science, ORCID
Added: August 6, 2018
2012 conference paper
Vehicle effects on the absorption of finite and infinite saturated doses of caffeine, mannitol, and testosterone in porcine skin.
[Poster Session]. Toxicologist, 126, 123. https://www.toxicology.org/pubs/docs/Tox/2012Tox.pdf
Event: 51st Annual Meeting and ToxExpo at San Francisco, CA on March 11-15, 2012
Source: NC State University Libraries
Added: June 17, 2022
2011 chapter
Absorption, penetration and cutaneous toxicity of jet fuel and hydrocarbon components
In M. Witten, E. Zeiger, & G. D. Ritchie (Eds.), Jet Fuel Toxicology (pp. 119–134). Boca Raton, FL.: CRC Press:
Ed(s): M. Witten, E. Zeiger & G. Ritchie
Source: NC State University Libraries
Added: June 17, 2022
2011 book
Comparative Pharmacokinetics: Principles, Techniques and Applications
(2nd ed.). Chichester, West Sussex, UK: Wiley-Blackwell.
Source: NC State University Libraries
Added: June 17, 2022
2011 book
Comparative pharmacokinetics principles, techniques, and applications
Source: NC State University Libraries
Added: August 6, 2018
2011 conference paper
Dermal penetration of UVB-damaged skin by titanium- and zinc oxide nanoparticles in sunscreen formulations
[Poster]. Naunyn-Schmiedebergs Archives of Pharmacology, 383(S1), 101.
Event: 77th Annual Meeting Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie e.V. at Frankfurt am Main, Germany on March 30 - April 1, 2011
Source: NC State University Libraries
Added: June 17, 2022
2011 conference paper
Development of physiologically based pharmacokinetic (PBPK) model to predict tulathromycin distribution in goats
[Abstract]. The Toxicologist, 120(2), 153. https://www.toxicology.org/pubs/docs/Tox/2011Tox.pdf
Event: 50th Anniversary Annual Meeting and ToxExpo at Washington, D.C. on March 6-10, 2011
Source: NC State University Libraries
Added: June 17, 2022
2011 conference paper
Evaluation of toxicity and inflammation in three different hydroxylated fullerenes (C60(OH)x inhuman cells
[Abstract]. The Toxicologist, 120(2), 251. https://www.toxicology.org/pubs/docs/Tox/2011Tox.pdf
Event: 50th Anniversary Annual Meeting and ToxExpo at Washington, D.C. on March 6-10, 2011
Source: NC State University Libraries
Added: June 17, 2022
2011 conference paper
In vitro evaluation of the effects of dose, receptor fluid, and vehicle on the absorption of five physiochemically different compounds in porcine skin
[Abstract]. The Toxicologist, 120, 136. https://www.toxicology.org/pubs/docs/Tox/2011Tox.pdf
Event: 50th Anniversary Annual Meeting and ToxExpo at Washington, D.C. on March 6-10, 2011
Source: NC State University Libraries
Added: June 17, 2022
2011 journal article
In vitro toxicity assessment of three hydroxylated fullerenes in human skin cells
TOXICOLOGY IN VITRO, 25(8), 2105–2112.
co-author countries:
United States of America 🇺🇸
Contributors: J. Saathoff n, A. Inman n, X. Xia n, n & N. Monteiro-Riviere n
author keywords: Hydroxylated fullerenes; Fullerenes; Cytotoxicity; Skin cells; Keratinocytes; Nanoparticles
MeSH headings : Biological Transport; Cell Survival; Cells, Cultured; Fullerenes / chemistry; Fullerenes / metabolism; Fullerenes / toxicity; Humans; Hydroxylation; Interleukin-8 / metabolism; Keratinocytes / drug effects; Keratinocytes / metabolism; Keratinocytes / ultrastructure; Microscopy, Electron, Transmission; Photoelectron Spectroscopy; Spectrometry, Fluorescence
Sources: Web Of Science, ORCID
Added: August 6, 2018
2011 conference paper
Iron oxide nanoparticles cause oxidative stress and dermal toxicity
[Abstract]. The Toxicologist, 120(2), 444. https://www.toxicology.org/pubs/docs/Tox/2011Tox.pdf
Event: 50th Anniversary Annual Meeting and ToxExpo at Washington, D.C. on March 6-10, 2011
Source: NC State University Libraries
Added: June 17, 2022
2011 journal article
Mapping the Surface Adsorption Forces of Nanomaterials in Biological Systems
ACS NANO, 5(11), 9074–9081.