Jim E Riviere

Data-driven methodology for discovery and response to pulmonary symptomology in hypertension through AI and machine learning: Application to COVID-19 related pharmacovigilance

Development and Application of an interactive Physiologically Based Pharmacokinetic (iPBPK) Model to Predict Oxytetracycline Tissue Distribution and Withdrawal Intervals in Market-Age Sheep and Goats

Toxicological Sciences.

Percutaneous Absorption of Chemical Mixtures

In N. Dragićević (Ed.), Percutaneous Absorption (5th ed., pp. 305–314).

Pulmonary adverse drug event data in hypertension with implications on COVID-19 morbidity

SCIENTIFIC REPORTS.

A study to assess the correlation between plasma, oral fluid and urine concentrations of flunixin meglumine with the tissue residue depletion profile in finishing-age swine

BMC Veterinary Research, 16(1).

Development and application of an interactive physiological based pharmacokinetic (iPBPK) model interface to estimate withdrawal intervals for penicillin G in cattle and swine

The Toxicologist, 174(1), 458.

Meta-Analysis of Nanoparticle Delivery to Tumors Using a Physiologically Based Pharmacokinetic Modeling and Simulation Approach

ACS Nano, 14(3), 3075–3095.

Pharmacovigilance in patients with diabetes: A data-driven analysis identifying specific RAS antagonists with adverse pulmonary safety profiles that have implications for COVID-19 morbidity and mortality

Journal of the American Pharmacists Association, 60(6), e145–e152.

Physiological parameter values for physiologically based pharmacokinetic models in food-producing animals. Part 1: Cattle and Swine

The Toxicologist, 174(1), 461.

Physiological parameter values for physiologically based pharmacokinetic models in food-producing animals. Part I: Cattle and swine

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS.

Physiological parameter values for physiologically based pharmacokinetic models in food-producing animals. Part II: Chicken and turkey

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS.

Physiological parameter values for physiologically based pharmacokinetic models in food‐producing animals. Part III: Sheep and goat

Journal of Veterinary Pharmacology and Therapeutics, 44(4), 456–477.

Physiologically based pharmacokinetic modeling and simulation of nanoparticle delivery to tumors in mice

The Toxicologist, 174(1), 460.

An integrated experimental and physiologically based pharmacokinetic modeling study of penicillin G in heavy sows

Journal of Veterinary Pharmacology and Therapeutics, 42(4), 461–475.

Assessing delivery efficiency of nanoparticles to tumors in tumor-bearing mice using a physiologically based pharmacokinetic modeling and simulation approach

The Toxicologist, 168(1), 476–477,

Data Science

SCIENCE BREAKTHROUGHS TO ADVANCE FOOD AND AGRICULTURAL RESEARCH BY 2030, pp. 145–164.

Development and application of a population physiologically based pharmacokinetic model for florfenicol and its metabolite florfenicol amine in cattle

FOOD AND CHEMICAL TOXICOLOGY, 126, 285–294.

Extralabel drug use in wildlife and game animals

Journal of the American Veterinary Medical Association, 255(5), 555–568.

Integration of Food Animal Residue Avoidance Databank (FARAD) Empirical Methods for Drug Withdrawal Interval Determination with a Mechanistic Population-Based Interactive Physiologically Based Pharmacokinetic (iPBPK) Modeling Platform: Example for Flunixin Meglumine Administration

The Toxicologist, 168(1), 191.

Integration of Food Animal Residue Avoidance Databank (FARAD) empirical methods for drug withdrawal interval determination with a mechanistic population-based interactive physiologically based pharmacokinetic (iPBPK) modeling platform: example for flunixin meglumine administration

Archives of Toxicology, 93(7), 1865–1880.

Making Sense of Pharmacovigilance and Drug Adverse Event Reporting: Comparative Similarity Association Analysis Using AI Machine Learning Algorithms in Dogs and Cats

Topics in Companion Animal Medicine, 37, 100366.

Novel Data Sharing Agreement to Accelerate Big Data Translational Research Projects in the One Health Sphere

Topics in Companion Animal Medicine, 37, 100367.

A general physiologically-based pharmacokinetic model for gold nanoparticles of different sizes with multiple administration routes in rats

The Toxicologist, 162(1), 526.

Absorption, Distribution, Metabolism, and Elimination

In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 8–40). Ames, Iowa: Wiley-Blackwell.

Aminoglycoside Antibiotics

In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 877–902). Ames, Iowa: Wiley-Blackwell.

Antiarrhythmic Agents

In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 537–552). Ames, Iowa: Wiley-Blackwell.

Application of population physiologically-based pharmacokinetic model for penicillin G in dairy cows to facilitate food safety assessment

The Toxicologist, 162(1), 526.

Automation and applications of the tolerance limit method in estimating meat withdrawal periods for veterinary drugs

Computers and Electronics in Agriculture, 146, 125–135.

Chemical Residues in Tissues of Food Animals

In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 1469–1480). Ames, Iowa: Wiley-Blackwell.

Consequences of fipronil exposure in egg-laying hens

Journal of the American Veterinary Medical Association, 253(1), 57–60.

Dermatopharmacology: Drugs Acting Locally on the Skin

In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 1278–1301). Ames, Iowa: Wiley-Blackwell.

Dosage Forms and Veterinary Feed Directives

In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 1459–1464). Ames, Iowa: Wiley-Blackwell.

Editorial

Journal of Veterinary Pharmacology and Therapeutics, 41(3), 355–355.

Extralabel drug use in small ruminants

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 253(8), 1001–1009.

Impact of natural compounds on dermal absorption for consumer products and their computational prediction

The Toxicologist, 162(1), 179.

Mathematical modeling and simulation in animal health. Part III: Using nonlinear mixed-effects to characterize and quantify variability in drug pharmacokinetics

Journal of Veterinary Pharmacology and Therapeutics, 41(2), 171–183.

Modeling gold nanoparticle biodistribution after arterial infusion into perfused tissue: effects of surface coating, size and protein corona

Nanotoxicology, 12(10), 1093–1112.

Pharmacokinetics

In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 41–64). Ames, Iowa: Wiley-Blackwell.

Probabilistic Physiologically Based Pharmacokinetic Model for Penicillin G in Milk From Dairy Cows Following Intramammary or Intramuscular Administrations

Toxicological Sciences, 164(1), 85–100.

Probabilistic risk assessment of gold nanoparticles after intravenous administration by integrating in vitro and in vivo toxicity with physiologically based pharmacokinetic modeling

Nanotoxicology, 12(5), 453–469.

Probabilistic risk assessment of gold nanoparticles by integrating in vitro and in vivo toxicity with physiologically-based pharmacokinetic modeling

The Toxicologist, 162(1), 526.

Tetracycline Antibiotics

In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 858–876). Ames, Iowa: Wiley-Blackwell.

Variation in fluoroquinolone pharmacodynamic parameter values among isolates of two bacterial pathogens of bovine respiratory disease

Scientific Reports, 8(1).

Veterinary Pharmacology and Therapeutics

(10th ed.). Ames, Iowa: Wiley-Blackwell.

Veterinary Pharmacology: An Introduction to the Discipline

In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 3–7). Ames, Iowa: Wiley-Blackwell.

Avoiding violative flunixin meglumine residues in cattle and swine

Journal of the American Veterinary Medical Association, 250(2), 182–189.

Biocorona formation on gold nanoparticles modulates human proximal tubule kidney cell uptake, cytotoxicity and gene expression

Toxicology in Vitro, 42, 150–160.

Considerations for extralabel drug use in calves

Journal of the American Veterinary Medical Association, 250(11), 1275–1282.

Development and application of a population physiologically based pharmacokinetic model for penicillin G in swine and cattle for food safety assessment

Food and Chemical Toxicology, 107, 74–87.

Guide to FARAD resources: historical and future perspectives

Journal of the American Veterinary Medical Association, 250(10), 1131–1139.

NanoEHS beyond toxicity – focusing on biocorona

Environmental Science: Nano, 4(7), 1433–1454.

Performance Assessment and Translation of Physiologically Based Pharmacokinetic Models From acslX to Berkeley Madonna, MATLAB, and R Language: Oxytetracycline and Gold Nanoparticles As Case Examples

Toxicological Sciences, 158(1), 23–35.

Pharmacokinetics of Mequindox and Its Marker Residue 1,4-Bisdesoxymequindox in Swine Following Multiple Oral Gavage and Intramuscular Administration: An Experimental Study Coupled with Population Physiologically Based Pharmacokinetic Modeling

Journal of Agricultural and Food Chemistry, 65(28), 5768–5777.

Zinc Oxide Nanoparticle–Poly I:C RNA Complexes: Implication as Therapeutics against Experimental Melanoma

Molecular Pharmaceutics, 14(3), 614–625.

A computational framework for interspecies pharmacokinetics, exposure and toxicity assessment of gold nanoparticles

Nanomedicine, 11(2), 107–119.

Assessment of penetrant and vehicle mixture properties on transdermal permeability using a mixed effect pharmacokinetic model of ex vivo porcine skin

Biopharmaceutics & Drug Disposition, 37(7), 387–396.

Biological and environmental surface interactions of nanomaterials: characterization, modeling, and prediction

Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 9(3), e1440.

Exploring Post-Treatment Reversion of Antimicrobial Resistance in Enteric Bacteria of Food Animals as a Resistance Mitigation Strategy

Foodborne Pathogens and Disease, 13(11), 610–617.

Mathematical modeling and simulation in animal health – Part II : principles, methods, applications, and value of physiologically based pharmacokinetic modeling in veterinary medicine and food safety assessment

Journal of Veterinary Pharmacology and Therapeutics, 39(5), 421–438.

Mathematical modeling and simulation in animal health. Part I: Moving beyond pharmacokinetics

Journal of Veterinary Pharmacology and Therapeutics, 39(3), 213–223.

Mechanistic Toxicity Assessment of Hexahydroisohumulone in Canine Hepatocytes, Renal Proximal Tubules, Bone Marrow-Derived Mesenchymal Stem Cells, and Enterocyte-like Cells

International Journal of Veterinary Health Science & Research, 4(2), 88–103.

Pharmacokinetics and tissue elimination of flunixin in veal calves

American Journal of Veterinary Research, 77(6), 634–640.

Protein corona modulation of hepatocyte uptake and molecular mechanisms of gold nanoparticle toxicity

Nanotoxicology, 11(1), 64–75.

Protocol for diversion of confirmed positive bulk raw milk tankers to calf ranches – A review of the Pharmacokinetics of tetracyclines and sulfonamides in veal calves

Animal Health Research Reviews, 17(2), 127–136.

Quantification of nanoparticle pesticide adsorption: computational approaches based on experimental data

Nanotoxicology, 10(8), 1118–1128.

Screening and Confirmatory Analyses of Flunixin in Tissues and Bodily Fluids after Intravenous or Intramuscular Administration to Cull Dairy Cows with or without Lipopolysaccharide Challenge

Journal of Agricultural and Food Chemistry, 64(1), 336–345.

Comparison of pharmacokinetics and milk elimination of flunixin in healthy cows and cows with mastitis

Journal of the American Veterinary Medical Association, 246(1), 118–125.

Development and Application of a Multiroute Physiologically Based Pharmacokinetic Model for Oxytetracycline in Dogs and Humans

Journal of Pharmaceutical Sciences, 104(1), 233–243.

In vitro safety assessment of food ingredients in canine renal proximal tubule cells

Toxicology in Vitro, 29(2), 289–298.

Pharmacokinetics and pharmacodynamics of gamithromycin in pulmonary epithelial lining fluid in naturally occurring bovine respiratory disease in multisource commingled feedlot cattle

Journal of Veterinary Pharmacology and Therapeutics, 39(2), 157–166.

Predicting the impact of biocorona formation kinetics on interspecies extrapolations of nanoparticle biodistribution modeling

Nanomedicine, 10(1), 25–33.

Dermal Exposure and Absorption of Chemicals and Nanomaterials

In Reference Module in Biomedical Sciences.

Development of a physiologically based pharmacokinetic model for flunixin in cattle (Bos taurus)

Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment, 31(9), 1506–1521.

In silico models to predict dermal absorption from complex agrochemical formulations

SAR and QSAR in Environmental Research, 25(7), 565–588.

Prediction of formulation effects on dermal absorption of topically applied ectoparasiticides dosed in vitro on canine and porcine skin using a mixture-adjusted quantitative structure permeability relationship

Journal of Veterinary Pharmacology and Therapeutics, 37(5), 435–444.

development of a mixed-effect pharmacokinetic model for vehicle modulated in vitro transdermal flux of topically applied penetrants

Journal of Pharmaceutical Sciences, 103(3), 1002–1012.

Comparison of ELISA and LC-MS/MS for the measurement of Flunixin plasma concentrations in beef cattle after intravenous and subcutaneous administration

Journal of Agricultural and Food Chemistry, 61(11), 2679–2686.

Oxidative stress and dermal toxicity of iron oxide nanoparticles in vitro

Cell Biochemistry and Biophysics, 67(2), 461–476.

Predicting skin permeability from complex vehicles

[Review of ]. Advanced Drug Delivery Reviews, 65(2), 265–277.

Protein binding modulates the cellular uptake of silver nanoparticles into human cells: Implications for in vitro to in vivo extrapolations?

Toxicology Letters, 220(3), 286–293.

Acute vascular effects of nanoparticle infusion in isolated perfused skin

Nanomedicine : Nanotechnology, Biology and Medicine, 8(4), 428–431.

Development of a physiologically based pharmacokinetic model to predict tulathromycin distribution in goats

Journal of Veterinary Pharmacology and Therapeutics, 35(2), 121–131.

Evaluation of factors important in modeling plasma concentrations of tetracycline hydrochloride administered in water in swine

American Journal of Veterinary Research, 73(10), 1641–1649.

In vitro biodistribution of silver nanoparticles in isolated perfused porcine skin flaps

Journal of Applied Toxicology, 32(11), 913–919.

Lack of hydroxylated fullerene toxicity after intravenous administration to female Sprague-Dawley rats

Journal of Toxicology and Environmental Health. Part A, 75(7), 367–373.

Pharmacokinetics and tissue elimination of tulathromycin following subcutaneous administration in meat goats

American Journal of Veterinary Research, 73(10), 1634–1640.

Quantum dot penetration into viable human skin

Nanotoxicology, 6(2), 173–185.

The effect of formulations and experimental conditions on in vitro human skin permeation-Data from updated EDETOX database

International Journal of Pharmaceutics, 434(1-2), 280–291.

Tulathromycin assay validation and tissue residues after single and multiple subcutaneous injections in domestic goats (Capra aegagrus hircus)

Journal of Veterinary Pharmacology and Therapeutics, 35(2), 113–120.

Comparative pharmacokinetics principles, techniques, and applications

In vitro toxicity assessment of three hydroxylated fullerenes in human skin cells

Toxicology in Vitro, 25(8), 2105–2112.

Mapping the surface adsorption forces of nanomaterials in biological systems

ACS Nano, 5(11), 9074–9081.

Pet food safety: a shared concern

British Journal of Nutrition, 106, S78–84.

Pharmacokinetics of tulathromycin after single and multiple subcutaneous injections in domestic goats (Capra aegagrus hircus)

Journal of Veterinary Pharmacology and Therapeutics, 34(5), 448–454.

Pharmacokinetics of tulathromycin following subcutaneous administration in meat goats

Research in Veterinary Science, 90(3), 477–479.

Predicting skin permeability from complex chemical mixtures: Dependency of quantitative structure permeation relationships on biology of skin model used

Toxicological Sciences, 119(1), 224–232.

Safety evaluation of sunscreen formulations containing titanium dioxide and zinc oxide nanoparticles in UVB sunburned skin: An in vitro and in vivo study

Toxicological Sciences, 123(1), 264–280.

An index for characterization of nanomaterials in biological systems

Nature Nanotechnology, 5(9), 671–675.

Disposition of melamine residues in blood and milk from dairy goats exposed to an oral bolus of melamine

Food and Chemical Toxicology, 48(8-9), 2542–2546.

Evaluation of perfused porcine skin as a model system to quantitate tissue distribution of fullerene nanoparticles

Toxicology Letters, 197(1), 1–6.

Intrinsic biological property of colloidal fullerene nanoparticles (nC(60)): Lack of lethality after high dose exposure to human epidermal and bacterial cells

Toxicology Letters, 197(2), 128–134.

Modelling the effect of mixture components on permeation through skin

International Journal of Pharmaceutics, 398(1-2), 28–32.

New Technologies for Application to Veterinary Medicine

In F. Cunningham, J. Elliott, & P. Lees (Eds.), Comparative and Veterinary Pharmacology (pp. 191–210).

Riviere and Brooks pig skin flow-through [data file]

Skin penetration and kinetics of pristine fullerenes (C-60) topically exposed in industrial organic solvents

Toxicology and Applied Pharmacology, 242(1), 29–37.

Surfactant effects on skin absorption of model organic chemicals: Implications for dermal risk assessment studies

Journal of Toxicology and Environmental Health. Part A, 73(11), 725–737.

Validated models for predicting skin penetration from different vehicles

European Journal of Pharmaceutical Sciences, 41(5), 612–616.

A physiologically based pharmacokinetic model linking plasma protein binding interactions with drug disposition

Research in Veterinary Science, 86(2), 293–301.

Comparison of quantum dot biodistribution with a blood-flow-limited physiologically based pharmacokinetic model

Nano Letters, 9(2), 794–799.

Dermal permeation of biocides and aromatic chemicals in three generic formulations of metalworking fluids

Journal of Toxicology and Environmental Health. Part A, 72(13), 832–841.

Determination of the effective dermal penetration barrier pH of porcine skin

Journal of Veterinary Pharmacology and Therapeutics, 32(4), 407–410.

Pharmacokinetics of nanomaterials: An overview of carbon nanotubes, fullerenes and quantum dots (vol 1, pg 26, 2008)

Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology, Vol. 1, pp. 685–685.

Pharmacokinetics of nanomaterials: an overview of carbon nanotubes, fullerenes and quantum dots

[Review of ]. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology, 1(1), 26–34.

Pharmacology of tetracycline water medication in swine

Journal of Animal Science, 87(10), 3179–3186.

Selection of appropriate training set of chemicals for modeling dermal permeability using uniform coverage design

QSAR & Combinatorial Science, 28(11-12), 1478–1486.

Update on drugs prohibited from extralabel use in food animals

Journal of the American Veterinary Medical Association, 235(5), 528–534.

A solvatochromatic approach to quantifying formulation effects on dermal permeability

SAR and QSAR in Environmental Research, 19(7-8), 615–630.

Animal skin morphology and dermal absorption

In M. S. Roberts & K. A. Walters (Eds.), Dermal absorption and toxicity assessment (2nd ed., pp. 17–35). New York: Informa Healthcare.

Application of linear solvation energy relationships to a custom-made polyaniline solid-phase microextraction fiber and three commercial fibers

Journal of Chromatography. A, 1188(2), 108–117.

Estimating meat withdrawal times in pigs exposed to melamine contaminated feed using a physiologically based pharmacokinetic model

Regulatory Toxicology and Pharmacology, 51(3), 324–331.

FARAD digest - Extralabel use of nonsteroidal anti-inflammatory drugs in cattle

Journal of the American Veterinary Medical Association, 232(5), 697–701.

Inhibition of jet fuel aliphatic hydrocarbon induced toxicity in human epidermal keratinocytes

Journal of Applied Toxicology, 28(4), 543–553.

Percutaneous absorption of complex chemical mixtures

In Marzulli and Maibach's dermatotoxicology (7th ed.) (pp. 63–70). New York: Taylor and Francis.

Pharmacokinetics of melamine in pigs following intravenous administration

Food and Chemical Toxicology, 46(3), 1196–1200.

Quantification of chemical mixture interactions modulating dermal absorption using a multiple membrane fiber array

Chemical Research in Toxicology, 21(3), 591–599.

Solvents and vehicle effects on the skin

In M. S. Roberts & K. A. Walters (Eds.), Dermal absorption and toxicity assessment. (2nd ed.) (pp. 433–447). New York: Informa Healthcare.

Sulfamethazine water medication pharmacokinetics and contamination in a commercial pig production unit

Journal of Food Protection, 71(3), 584–589.

Veterinary pharmacology and therapeutics

Ames, IA: Blackwell Publishing.

A system coefficient approach for quantitative assessment of the solvent effects on membrane absorption from chemical mixtures

SAR and QSAR in Environmental Research, 18(5-6), 579–593.

An experimentally based approach for predicting skin permeability of chemicals and drugs using a membrane-coated fiber array

Toxicology and Applied Pharmacology, 221(3), 320–328.

Biodistribution of quantum dot nanoparticles in perfused skin: Evidence of coating dependency and periodicity in arterial extraction

Nano Letters, 7(9), 2865–2870.

Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework

Toxicology and Applied Pharmacology, 222, 122–128.

Current update on drugs for game bird species

Journal of the American Veterinary Medical Association, 231(10), 1506–1508.

Dermal toxicity

In Veterinary toxicology: basic and clinical principles (pp. 263–276).

Dermatotoxicology: Computational risk assessment

In Computational toxicology: risk assessment for pharmaceutical and environmental chemicals (pp. 677–692).

Managing canine obesity: a new therapeutic approach

Journal of Veterinary Pharmacology and Therapeutics, 30(Suppl.).

Membrane-coated fiber array approach for predicting skin permeability of chemical mixtures from different vehicles

Toxicological Sciences, 99(1), 153–161.

Naive averaged, nave pooled, and population pharmacokinetics of orally administered marbofloxacin in juvenile harbor seals

Journal of the American Veterinary Medical Association, 230(3), 390–395.

Partitioning behavior of aromatic components in jet fuel into diverse membrane-coated fibers

Journal of Toxicology and Environmental Health. Part A, 70(22), 1879–1887.

Pharmacokinetics of nanomaterials

In Nanotoxicology: characterization, dosing and health effects (pp. 127–152). New York: Informa.

Physiological based pharmacokinetic modeling

In Veterinary toxicology: basic and clinical principles (pp. 42–50).

Predicting dermal permeability of biocides in commercial cutting fluids using a LSER approach

Toxicology Letters, 175(1-3), 34–43.

Prediction of dermal absorption from complex chemical mixtures: incorporation of vehicle effects and interactions into a QSPR framework

SAR and QSAR in Environmental Research, 18(1-2), 31–44.

Quantitating the absorption, partitioning and toxicity of hydrocarbon components of JP-8 jet fuel

(Center for Chemical Toxicology Research and Pharmacokinetics Grant No. FA9550-04-1-0376).

Regression method of the hydrophobicity for determining octanol/water partition ruler approach coefficients of very hydrophobic compounds

Chemosphere, 66(6), 1086–1093.

Surface coatings determine cytotoxicity and irritation potential of quantum dot nanoparticles in epidermal keratinocytes

Journal of Investigative Dermatology, 127(1), 143–153.

The future of veterinary therapeutics: A glimpse towards 2030

[Review of ]. Veterinary Journal, 174(3), 462–471.

Variables influencing interactions of untargeted quantum dot nanoparticles with skin cells and identification of biochemical modulators

Nano Letters, 7(5), 1344–1348.

A physiologically based pharmacokinetic model of organophosphate dermal absorption

Toxicological Sciences, 89(1), 188–204.

Application of risk assessment and management principles to the extralabel use of drugs in food-producing animals

Journal of Veterinary Pharmacology and Therapeutics, 29(1), 5–14.

Biological concepts and techniques in toxicology : an integrated approach

Cluster analysis of the dermal permeability and stratum corneum/solvent partitioning of ten chemicals in twenty-four chemical mixtures in porcine skin

Skin Pharmacology and Physiology, 19(4), 198–206.

Dermal absorption models in toxicology and pharmacology

(p. ). Boca Raton: Taylor Francis/CRC Press.

Dermal absorption/toxicity of organophosphates and carbamates

In Toxicology of organophosphates and carbamate pesticides (pp. 411–422).

Extralabel use of penicillin in food animals

Journal of the American Veterinary Medical Association, 229(9), 1401–1403.

In vivo models

In Dermal absorption models in toxicology and pharmacology (pp. 47–68). New York: Taylor and Francis / CRC Press.

Introduction and overview

In Biological concepts and techniques in toxicology: an integrated approach (pp. 1–3). New York: Taylor and Francis.

Penetration of intact skin by quantum dots with diverse physicochemical properties

Toxicological Sciences, 91(1), 159–165.

Percutaneous absorption of chemical mixtures

In Dermal absorption models in toxicology and pharmacology (pp. 281–301). New York: Taylor and Francis / CRC Press.

Perfused skin models

In Dermal absorption models in toxicology and pharmacology (pp. 27–45). New York: Taylor and Francis / CRC Press.

Pharmacokinetic modeling of dermal absorption

Journal of Veterinary Pharmacology and Therapeutics, 29(S1), 244–245.

Pharmacokinetics of flunixin meglumine in swine after intravenous dosing

Journal of Veterinary Pharmacology and Therapeutics, 29(5), 437–440.

Skin penetration, cytotoxicity, proteomic analyses, and inflammatory potential of nanomaterials; fullerenes, multi-walled carbon nanotubes and quantum dots

Journal of Veterinary Pharmacology and Therapeutics, 29(Sup. 1), 196–197.

Tabulation of FARAD Comparative and Veterinary Pharmacokinetic Data

Ames, IA: Blackwell Publishing.

Toxicity of jet fuel aliphatic and aromatic hydrocarbon mixtures on human epidermal keratinocytes: evaluation based on in vitro cytotoxicity and interleukin-8 release

Archives of Toxicology, 80(8), 508–523.

Trace analysis of fullerenes in biological samples by simplified liquid-liquid extraction and high-performance liquid chromatography

Journal of Chromatography. A, 1129(2), 216–222.

Use of probabilistic modeling within a physiologically based pharmacokinetic model to predict sulfamethazine residue withdrawal times in edible tissues in swine

Antimicrobial Agents and Chemotherapy, 50(7), 2344–2351.

Aminoglycoside residues in food of animal origin

Journal of the American Veterinary Medical Association, 227(1), 63–66.

Antidotes in food animal practice

Journal of the American Veterinary Medical Association, 226(6), 884–887.

Comparative in vivo toxicity of topical JP-8 jet fuel and its individual hydrocarbon components: Identification of tridecane and tetradecane as key constituents responsible for dermal irritation

Toxicologic Pathology, 33(2), 258–266.