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2020 article
Physiological parameter values for physiologically based pharmacokinetic models in food-producing animals. Part I: Cattle and swine
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS.
2020 article
Physiological parameter values for physiologically based pharmacokinetic models in food-producing animals. Part II: Chicken and turkey
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS.
2019 article
Data Science
SCIENCE BREAKTHROUGHS TO ADVANCE FOOD AND AGRICULTURAL RESEARCH BY 2030, pp. 145–164.
2019 journal article
Development and application of a population physiologically based pharmacokinetic model for florfenicol and its metabolite florfenicol amine in cattle
FOOD AND CHEMICAL TOXICOLOGY, 126, 285–294.
2018 journal article
Automation and applications of the tolerance limit method in estimating meat withdrawal periods for veterinary drugs
Computers and Electronics in Agriculture, 146, 125–135.
2018 journal article
Editorial
Journal of Veterinary Pharmacology and Therapeutics, 41(3), 355–355.
2018 journal article
Extralabel drug use in small ruminants
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 253(8), 1001–1009.
2015 journal article
Comparison of pharmacokinetics and milk elimination of flunixin in healthy cows and cows with mastitis
Journal of the American Veterinary Medical Association, 246(1), 118–125.
2014 journal article
Development of a physiologically based pharmacokinetic model for flunixin in cattle (Bos taurus)
Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment, 31(9), 1506–1521.
2014 journal article
In silico models to predict dermal absorption from complex agrochemical formulations
SAR and QSAR in Environmental Research, 25(7), 565–588.
2014 journal article
Prediction of formulation effects on dermal absorption of topically applied ectoparasiticides dosed in vitro on canine and porcine skin using a mixture-adjusted quantitative structure permeability relationship
Journal of Veterinary Pharmacology and Therapeutics, 37(5), 435–444.
2014 journal article
development of a mixed-effect pharmacokinetic model for vehicle modulated in vitro transdermal flux of topically applied penetrants
Journal of Pharmaceutical Sciences, 103(3), 1002–1012.
2013 journal article
Comparison of ELISA and LC-MS/MS for the measurement of Flunixin plasma concentrations in beef cattle after intravenous and subcutaneous administration
Journal of Agricultural and Food Chemistry, 61(11), 2679–2686.
2013 journal article
Oxidative stress and dermal toxicity of iron oxide nanoparticles in vitro
Cell Biochemistry and Biophysics, 67(2), 461–476.
2013 review
Predicting skin permeability from complex vehicles
[Review of ]. Advanced Drug Delivery Reviews, 65(2), 265–277.
2013 journal article
Protein binding modulates the cellular uptake of silver nanoparticles into human cells: Implications for in vitro to in vivo extrapolations?
Toxicology Letters, 220(3), 286–293.
2012 journal article
Acute vascular effects of nanoparticle infusion in isolated perfused skin
Nanomedicine : Nanotechnology, Biology and Medicine, 8(4), 428–431.
2012 journal article
Development of a physiologically based pharmacokinetic model to predict tulathromycin distribution in goats
Journal of Veterinary Pharmacology and Therapeutics, 35(2), 121–131.
2012 journal article
Evaluation of factors important in modeling plasma concentrations of tetracycline hydrochloride administered in water in swine
American Journal of Veterinary Research, 73(10), 1641–1649.
2012 journal article
In vitro biodistribution of silver nanoparticles in isolated perfused porcine skin flaps
Journal of Applied Toxicology, 32(11), 913–919.
2012 journal article
Lack of hydroxylated fullerene toxicity after intravenous administration to female Sprague-Dawley rats
Journal of Toxicology and Environmental Health. Part A, 75(7), 367–373.
2012 journal article
Pharmacokinetics and tissue elimination of tulathromycin following subcutaneous administration in meat goats
American Journal of Veterinary Research, 73(10), 1634–1640.
2012 journal article
Quantum dot penetration into viable human skin
Nanotoxicology, 6(2), 173–185.
2012 journal article
The effect of formulations and experimental conditions on in vitro human skin permeation-Data from updated EDETOX database
International Journal of Pharmaceutics, 434(1-2), 280–291.
2012 journal article
Tulathromycin assay validation and tissue residues after single and multiple subcutaneous injections in domestic goats (Capra aegagrus hircus)
Journal of Veterinary Pharmacology and Therapeutics, 35(2), 113–120.
2011 book
Comparative pharmacokinetics principles, techniques, and applications
2011 journal article
In vitro toxicity assessment of three hydroxylated fullerenes in human skin cells
Toxicology in Vitro, 25(8), 2105–2112.
2011 journal article
Mapping the surface adsorption forces of nanomaterials in biological systems
ACS Nano, 5(11), 9074–9081.
2011 journal article
Pet food safety: a shared concern
British Journal of Nutrition, 106, S78–84.
2011 journal article
Pharmacokinetics of tulathromycin after single and multiple subcutaneous injections in domestic goats (Capra aegagrus hircus)
Journal of Veterinary Pharmacology and Therapeutics, 34(5), 448–454.
2011 journal article
Pharmacokinetics of tulathromycin following subcutaneous administration in meat goats
Research in Veterinary Science, 90(3), 477–479.
2011 journal article
Predicting skin permeability from complex chemical mixtures: Dependency of quantitative structure permeation relationships on biology of skin model used
Toxicological Sciences, 119(1), 224–232.
2011 journal article
Safety evaluation of sunscreen formulations containing titanium dioxide and zinc oxide nanoparticles in UVB sunburned skin: An in vitro and in vivo study
Toxicological Sciences, 123(1), 264–280.
2010 journal article
An index for characterization of nanomaterials in biological systems
Nature Nanotechnology, 5(9), 671–675.
2010 journal article
Disposition of melamine residues in blood and milk from dairy goats exposed to an oral bolus of melamine
Food and Chemical Toxicology, 48(8-9), 2542–2546.
2010 journal article
Evaluation of perfused porcine skin as a model system to quantitate tissue distribution of fullerene nanoparticles
Toxicology Letters, 197(1), 1–6.
2010 journal article
Intrinsic biological property of colloidal fullerene nanoparticles (nC(60)): Lack of lethality after high dose exposure to human epidermal and bacterial cells
Toxicology Letters, 197(2), 128–134.
2010 journal article
Modelling the effect of mixture components on permeation through skin
International Journal of Pharmaceutics, 398(1-2), 28–32.
2010 dataset
Riviere and Brooks pig skin flow-through [data file]
2010 journal article
Skin penetration and kinetics of pristine fullerenes (C-60) topically exposed in industrial organic solvents
Toxicology and Applied Pharmacology, 242(1), 29–37.
2010 journal article
Surfactant effects on skin absorption of model organic chemicals: Implications for dermal risk assessment studies
Journal of Toxicology and Environmental Health. Part A, 73(11), 725–737.
2010 journal article
Validated models for predicting skin penetration from different vehicles
European Journal of Pharmaceutical Sciences, 41(5), 612–616.
2009 journal article
A physiologically based pharmacokinetic model linking plasma protein binding interactions with drug disposition
Research in Veterinary Science, 86(2), 293–301.
2009 journal article
Comparison of quantum dot biodistribution with a blood-flow-limited physiologically based pharmacokinetic model
Nano Letters, 9(2), 794–799.
2009 journal article
Dermal permeation of biocides and aromatic chemicals in three generic formulations of metalworking fluids
Journal of Toxicology and Environmental Health. Part A, 72(13), 832–841.
2009 journal article
Determination of the effective dermal penetration barrier pH of porcine skin
Journal of Veterinary Pharmacology and Therapeutics, 32(4), 407–410.
2009 article
Pharmacokinetics of nanomaterials: An overview of carbon nanotubes, fullerenes and quantum dots (vol 1, pg 26, 2008)
Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology, Vol. 1, pp. 685–685.
2009 review
Pharmacokinetics of nanomaterials: an overview of carbon nanotubes, fullerenes and quantum dots
[Review of ]. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology, 1(1), 26–34.
2009 journal article
Pharmacology of tetracycline water medication in swine
Journal of Animal Science, 87(10), 3179–3186.
2009 journal article
Selection of appropriate training set of chemicals for modeling dermal permeability using uniform coverage design
QSAR & Combinatorial Science, 28(11-12), 1478–1486.
2009 journal article
Update on drugs prohibited from extralabel use in food animals
Journal of the American Veterinary Medical Association, 235(5), 528–534.
2008 conference paper
A solvatochromatic approach to quantifying formulation effects on dermal permeability
SAR and QSAR in Environmental Research, 19(7-8), 615–630.
2008 journal article
Application of linear solvation energy relationships to a custom-made polyaniline solid-phase microextraction fiber and three commercial fibers
Journal of Chromatography. A, 1188(2), 108–117.
2008 journal article
Estimating meat withdrawal times in pigs exposed to melamine contaminated feed using a physiologically based pharmacokinetic model
Regulatory Toxicology and Pharmacology, 51(3), 324–331.
2008 journal article
FARAD digest - Extralabel use of nonsteroidal anti-inflammatory drugs in cattle
Journal of the American Veterinary Medical Association, 232(5), 697–701.
2008 journal article
Inhibition of jet fuel aliphatic hydrocarbon induced toxicity in human epidermal keratinocytes
Journal of Applied Toxicology, 28(4), 543–553.
2008 chapter
Percutaneous absorption of complex chemical mixtures
In Marzulli and Maibach's dermatotoxicology (7th ed.) (pp. 63–70). New York: Taylor and Francis.
2008 journal article
Pharmacokinetics of melamine in pigs following intravenous administration
Food and Chemical Toxicology, 46(3), 1196–1200.
2008 journal article
Quantification of chemical mixture interactions modulating dermal absorption using a multiple membrane fiber array
Chemical Research in Toxicology, 21(3), 591–599.
2008 chapter
Solvents and vehicle effects on the skin
In Dermal absorption and toxicity assessment. (2nd ed.) (pp. 433–447). New York: Informa Healthcare.
2008 journal article
Sulfamethazine water medication pharmacokinetics and contamination in a commercial pig production unit
Journal of Food Protection, 71(3), 584–589.
2008 book
Veterinary pharmacology and therapeutics
Ames, IA: Blackwell Publishing.
2007 journal article
A system coefficient approach for quantitative assessment of the solvent effects on membrane absorption from chemical mixtures
SAR and QSAR in Environmental Research, 18(5-6), 579–593.
2007 journal article
An experimentally based approach for predicting skin permeability of chemicals and drugs using a membrane-coated fiber array
Toxicology and Applied Pharmacology, 221(3), 320–328.
2007 journal article
Biodistribution of quantum dot nanoparticles in perfused skin: Evidence of coating dependency and periodicity in arterial extraction
Nano Letters, 7(9), 2865–2870.
2007 journal article
Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework
Toxicology and Applied Pharmacology, 222, 122–128.
2007 journal article
Current update on drugs for game bird species
Journal of the American Veterinary Medical Association, 231(10), 1506–1508.
2007 chapter
Dermal toxicity
In Veterinary toxicology: basic and clinical principles (pp. 263–276).
2007 chapter
Dermatotoxicology: Computational risk assessment
In Computational toxicology: risk assessment for pharmaceutical and environmental chemicals (pp. 677–692).
2007 journal article
Managing canine obesity: a new therapeutic approach
Journal of Veterinary Pharmacology and Therapeutics, 30(Suppl.).
2007 journal article
Membrane-coated fiber array approach for predicting skin permeability of chemical mixtures from different vehicles
Toxicological Sciences, 99(1), 153–161.
2007 journal article
Naive averaged, nave pooled, and population pharmacokinetics of orally administered marbofloxacin in juvenile harbor seals
Journal of the American Veterinary Medical Association, 230(3), 390–395.
2007 journal article
Partitioning behavior of aromatic components in jet fuel into diverse membrane-coated fibers
Journal of Toxicology and Environmental Health. Part A, 70(22), 1879–1887.
2007 chapter
Pharmacokinetics of nanomaterials
In Nanotoxicology: characterization, dosing and health effects (pp. 127–152). New York: Informa.
2007 chapter
Physiological based pharmacokinetic modeling
In Veterinary toxicology: basic and clinical principles (pp. 42–50).
2007 journal article
Predicting dermal permeability of biocides in commercial cutting fluids using a LSER approach
Toxicology Letters, 175(1-3), 34–43.
2007 journal article
Prediction of dermal absorption from complex chemical mixtures: incorporation of vehicle effects and interactions into a QSPR framework
SAR and QSAR in Environmental Research, 18(1-2), 31–44.
2007 journal article
Regression method of the hydrophobicity for determining octanol/water partition ruler approach coefficients of very hydrophobic compounds
Chemosphere, 66(6), 1086–1093.
2007 journal article
Surface coatings determine cytotoxicity and irritation potential of quantum dot nanoparticles in epidermal keratinocytes
Journal of Investigative Dermatology, 127(1), 143–153.
2007 review
The future of veterinary therapeutics: A glimpse towards 2030
[Review of ]. Veterinary Journal, 174(3), 462–471.
2007 journal article
Variables influencing interactions of untargeted quantum dot nanoparticles with skin cells and identification of biochemical modulators
Nano Letters, 7(5), 1344–1348.
2006 journal article
A physiologically based pharmacokinetic model of organophosphate dermal absorption
Toxicological Sciences, 89(1), 188–204.
2006 journal article
Application of risk assessment and management principles to the extralabel use of drugs in food-producing animals
Journal of Veterinary Pharmacology and Therapeutics, 29(1), 5–14.
2006 book
Biological concepts and techniques in toxicology : an integrated approach
2006 journal article
Cluster analysis of the dermal permeability and stratum corneum/solvent partitioning of ten chemicals in twenty-four chemical mixtures in porcine skin
Skin Pharmacology and Physiology, 19(4), 198–206.
2006 book
Dermal absorption models in toxicology and pharmacology
(p. ). Boca Raton: Taylor Francis/CRC Press.
2006 chapter
Dermal absorption/toxicity of organophosphates and carbamates
In Toxicology of organophosphates and carbamate pesticides (pp. 411–422).
2006 journal article
Extralabel use of penicillin in food animals
Journal of the American Veterinary Medical Association, 229(9), 1401–1403.
2006 chapter
In vivo models
In Dermal absorption models in toxicology and pharmacology (pp. 47–68). New York: Taylor and Francis / CRC Press.
2006 chapter
Introduction and overview
In Biological concepts and techniques in toxicology: an integrated approach (pp. 1–3). New York: Taylor and Francis.
2006 journal article
Penetration of intact skin by quantum dots with diverse physicochemical properties
Toxicological Sciences, 91(1), 159–165.
2006 chapter
Percutaneous absorption of chemical mixtures
In Dermal absorption models in toxicology and pharmacology (pp. 281–301). New York: Taylor and Francis / CRC Press.
2006 chapter
Perfused skin models
In Dermal absorption models in toxicology and pharmacology (pp. 27–45). New York: Taylor and Francis / CRC Press.
2006 journal article
Pharmacokinetic modeling of dermal absorption
Journal of Veterinary Pharmacology and Therapeutics, 29(S1), 244–245.
2006 journal article
Pharmacokinetics of flunixin meglumine in swine after intravenous dosing
Journal of Veterinary Pharmacology and Therapeutics, 29(5), 437–440.
2006 journal article
Skin penetration, cytotoxicity, proteomic analyses, and inflammatory potential of nanomaterials; fullerenes, multi-walled carbon nanotubes and quantum dots
Journal of Veterinary Pharmacology and Therapeutics, 29(Sup. 1), 196–197.
2006 book
Tabulation of FARAD Comparative and Veterinary Pharmacokinetic Data
Ames, IA: Blackwell Publishing.
2006 journal article
Toxicity of jet fuel aliphatic and aromatic hydrocarbon mixtures on human epidermal keratinocytes: evaluation based on in vitro cytotoxicity and interleukin-8 release
Archives of Toxicology, 80(8), 508–523.
2006 journal article
Trace analysis of fullerenes in biological samples by simplified liquid-liquid extraction and high-performance liquid chromatography
Journal of Chromatography. A, 1129(2), 216–222.
2006 journal article
Use of probabilistic modeling within a physiologically based pharmacokinetic model to predict sulfamethazine residue withdrawal times in edible tissues in swine
Antimicrobial Agents and Chemotherapy, 50(7), 2344–2351.
2005 journal article
Aminoglycoside residues in food of animal origin
Journal of the American Veterinary Medical Association, 227(1), 63–66.
2005 journal article
Antidotes in food animal practice
Journal of the American Veterinary Medical Association, 226(6), 884–887.
2005 journal article
Comparative in vivo toxicity of topical JP-8 jet fuel and its individual hydrocarbon components: Identification of tridecane and tetradecane as key constituents responsible for dermal irritation
Toxicologic Pathology, 33(2), 258–266.
2005 journal article
Comparative studies on the effects of water, ethanol and water/ethanol mixtures on chemical partitioning into porcine stratum corneum and silastic membrane
Toxicology in Vitro, 19(1), 69–77.
2005 journal article
Determination of the partition coefficients and absorption kinetic parameters of chemicals in a lipophilic membrane/water system by using a membrane-coated fiber technique
European Journal of Pharmaceutical Sciences, 24(1), 15–23.
2005 journal article
Development of a physiologic-based pharmacokinetic model for estimating sulfamethazine concentrations in swine and application to prediction of violative residues in edible tissues
American Journal of Veterinary Research, 66(10), 1686–1693.
2005 journal article
Effect of JP-8 jet fuel exposure on protein expression in human keratinocyte cells in culture
Toxicology Letters, 160(1), 8–21.
2005 journal article
Effect of formulation and route of administration on tissue residues and withdrawal times
Journal of the American Veterinary Medical Association, 227(10), 1574–1577.
2005 journal article
Effect of in vivo jet fuel exposure on subsequent in vitro dermal absorption of individual aromatic and aliphatic hydrocarbon fuel constituents
Journal of Toxicology and Environmental Health. Part A, 68(9), 719–737.
2005 journal article
Effect of vehicles and sodium lauryl sulphate on xenobiotic permeability and stratum corneum partitioning in porcine skin
Toxicology (Amsterdam, Netherlands), 206(3), 325–335.
2005 journal article
Extralabel intramammary use of drugs in dairy cattle
Journal of the American Veterinary Medical Association, 226(12), 1994–1996.
2005 journal article
Membrane uptake kinetics of jet fuel aromatic hydrocarbons from aqueous solutions studied by a membrane-coated fiber technique
Toxicology Mechanisms and Methods, 15(4), 307–316.
2005 journal article
Multi-walled carbon nanotube interactions with human epidermal keratinocytes
Toxicology Letters, 155(3), 377–384.
2005 journal article
Multivariate meta-analysis of pharmacokinetic studies of ampicillin trihydrate in cattle
American Journal of Veterinary Research, 66(1), 108–112.
2005 chapter
Percutaneous absorption of chemical mixtures
In Percutaneous absorption: drugs, cosmetics, mechanisms, methodology (4th ed.) (pp. 155–163). New York: Taylor and Francis / Marcel Dekker.
2005 conference paper
Pharmacokinetic and allometric techniques used by FARAD to estimate extended withdrawal times
Proc. 14th Biennial AAVPT Symposium, 14.
2005 journal article
Pre-treatment effects of trichloroethylene on the dermal absorption of the biocide, triazine
Toxicology Letters, 159(3), 252–260.
2005 journal article
Predicting skin permeability from complex chemical mixtures
Toxicology and Applied Pharmacology, 208(2), 99–110.
2005 conference paper
The pig as a model for human skin research
Swine in Biomedical Research: Update on Animal Models. Sinclair Research Center. 56th AALAS National Meeting, 56, 17–22.
2004 journal article
A compartment model for the membrane-coated fiber technique used for determining the absorption parameters of chemicals into lipophilic membranes
Pharmaceutical Research, 21(8), 1345–1352.
2004 journal article
A web-based decision support system to estimate extended withdrawal intervals
Computers and Electronics in Agriculture, 44(2), 145–151.
2004 journal article
Characterization of polyacrylate membrane-coated fibers used in chemical absorption studies with programmed thermal treatment and FT-IR microscopy
Analytical Chemistry, 76(14), 4245–4250.
2004 journal article
Comparative mixture effects of JP-8(100) additives on the dermal absorption and disposition of jet fuel hydrocarbons in different membrane model systems
Toxicology Letters, 150(3), 351–365.
2004 journal article
Current approved drugs for aquatic species
Journal of the American Veterinary Medical Association, 224(1), 50–51.
2004 journal article
Dose related absorption of JP-8 jet fuel hydrocarbons through porcine skin with quantitative structure permeability relationship analysis
Toxicology Mechanisms and Methods, 14(3), 159–166.
2004 journal article
Drugs approved for small ruminants
Journal of the American Veterinary Medical Association, 224(4), 520–523.
2004 journal article
Elimination kinetics of ceftiofur hydrochloride after intramammary administration in lactating dairy cows
Journal of the American Veterinary Medical Association, 224(11), 1827–1830.
2004 journal article
Feasibility of using half-life multipliers to estimate extended withdrawal intervals following the extralabel use of drugs in food-producing animals
Journal of Food Protection, 67(3), 555–560.
2004 journal article
Meta-analysis of pharmacokinetic data of veterinary drugs using the Food Animal Residue Avoidance Databank: oxytetracycline and procaine penicillin G
Journal of Veterinary Pharmacology and Therapeutics, 27(5), 343–353.
2004 journal article
Mixture additives inhibit the dermal permeation of the fatty acid, ricinoleic acid
Toxicology Letters, 147(1), 15–26.
2004 chapter
Percutaneous absorption of complex chemical mixtures
In Dermatotoxicology (6th ed.) (pp. 30–41). Boca Raton, FL: CRC Press.
2004 journal article
Skin toxicity of jet fuels: Ultrastructural studies and the effects of substance P
Toxicology and Applied Pharmacology, 195(3), 339–347.
2004 chapter
The isolated perfused porcine skin flap
In Dermatotoxicology (6th ed.) (pp. 564–588). Boca Raton, FL: CRC Press.
2004 journal article
Veterinary application of in vitro dissolution data and the biopharmaceutics classification system
Pharmacopeial Forum, 30, 2295–2303.
2003 journal article
A novel in-vitro technique for studying percutaneous permeation with a membrane-coated fiber and gas chromatography/mass spectrometry: Part I. Performances of the technique and determination of the permeation rates and partition coefficients of ?
Pharmaceutical Research, 20(2), 275–282.
2003 book
Comparative pharmacokinetics: principles, techniques and applications
(p. 327). Ames, IA: Blackwell Publishing (Iowa State Press).
2003 journal article
Dermal disposition of triazine in cutting fluid mixtures
Journal of Toxicology. Cutaneous and Ocular Toxicology, 22(4), 215–229.
2003 journal article
Evaluation of the advisory services provided by the Food Animal Residue Avoidance Databank
Journal of the American Veterinary Medical Association, 223(11), 1596–1598.
2003 journal article
In vitro percutaneous absorption of nonylphenol (Np) and nonylphenol ethoxylates (Npe-4 and Npe-9) in isolated perfused skin
Journal of Toxicology. Cutaneous and Ocular Toxicology, 22(1-2), 1–11.
2003 journal article
Mechanisms of skin absorption
Journal of Veterinary Pharmacology and Therapeutics, 26, 25.
2003 journal article
Percutaneous absorption of 2,6-di-tert-butyl-4-nitrophenol (DBNP) in isolated perfused porcine skin
Toxicology in Vitro, 17(3), 289–292.
2003 journal article
Percutaneous absorption of topical N,N-diethyl-m-toluamide (DEET): Effects of exposure variables and coadministered toxicants
Journal of Toxicology and Environmental Health. Part A, 66(2), 133–151.
2003 journal article
Pyridostigmine bromide modulates topical irritant-induced cytokine release from human epidermal keratinocytes and isolated perfused porcine skin
Toxicology (Amsterdam, Netherlands), 183(1-3), 15–28.
2003 journal article
The cytotoxicity of jet fuel aromatic hydrocarbons and dose- related interleukin-8 release from human epidermal keratinocytes
Archives of Toxicology, 77(7), 384–391.
2003 journal article
Update on FARAD food animal drug withholding recommendations
Journal of the American Veterinary Medical Association, 223(9), 1277-.
2002 journal article
Analysis of N,N-diethyl-m-toluamide in porcine skin perfusates using solid-phase extraction disks and reversed-phase high- performance liquid chromatography
Journal of Chromatography. B, 780(1), 45–52.
2002 journal article
Applying the biopharmaceutics classification system to veterinary pharmaceutical products Part II. Physiological considerations
Advanced Drug Delivery Reviews, 54(6), 825–850.
2002 book
Chemical food safety: A scientist's perspective
Ames, Iowa: Iowa State Press.
2002 journal article
Differential relationship between the carbon chain length of jet fuel aliphatic hydrocarbons and their ability to induce cytotoxicity vs. interleukin-8 release in human epidermal keratinocytes
Toxicological Sciences, 69(1), 226–233.
2002 journal article
Effect of chemical interactions in pentachlorophenol mixtures on skin and membrane transport
Toxicological Sciences, 69(2), 295–305.
2002 journal article
Extrapolated withdrawal-interval estimator (EWE) algorithm: A quantitative approach to establishing extralabel withdrawal times
Regulatory Toxicology and Pharmacology, 36(1), 131–137.
2002 journal article
Gulf War related exposure factors influencing topical absorption of C-14-permethrin
Toxicology Letters, 135(1-2), 61–71.
2002 journal article
Mixed-effects modeling of the interspecies pharmacokinetic scaling of oxytetracycline
Journal of Pharmaceutical Sciences, 91(2), 331–341.
2002 journal article
Physicochemical determinants of linear alkylbenzene sulfonate (LAS) disposition in skin exposed to aqueous cutting fluid mixtures
Toxicology and Industrial Health, 18(5), 237–248.
2002 journal article
Pyridostigmine bromide modulates the dermal disposition of [C- 14]permethrin
Toxicology and Applied Pharmacology, 181(3), 164–173.
2002 journal article
Systemic uptake and cutaneous disposition of pentachlorophenol in a sequential exposure scenario: Effects of skin preexposure to benzo[a] pyrene
Journal of Toxicology and Environmental Health. Part A, 65(18), 1307–1331.
2002 journal article
The use of enzyme histochemistry in detecting cutaneous toxicity of three topically applied jet fuel mixtures
Toxicology Mechanisms and Methods, 12(1), 17–34.
2002 journal article
Toxicokinetics and physiologically based toxicokinetics in toxicology and risk assessment
Journal of Toxicology and Environmental Health. Part B, Critical Reviews, 6(1), 1–40.
2001 chapter
Aminoglycoside antibiotics
In Veterinary pharmacology and therapeutics (8th ed.) (pp. 841–867). Ames, IA: Iowa State University Press.
2001 journal article
Analysis of interleukin-8 release from normal human epidermal keratinocytes exposed to aliphatic hydrocarbons: delivery of hydrocarbons to cell cultures via complexation with alpha-cyclodextrin
Toxicology in Vitro, 15(6), 663–669.
2001 chapter
Antifungal and antiviral drugs
In Veterinary Pharmacology: Therapeutics (8th ed.) (pp. 918–946). Ames, IA: Iowa State University Press.
2001 chapter
Antiseptics/disinfectants
In Veterinary Pharmacology: Therapeutics (8th ed.) (pp. 783–795). Ames, IA: Iowa State University Press.
2001 chapter
Chemical residues in tissues of food animals
In Veterinary pharmacology and therapeutics (8th ed.) (pp. 1166–1174). Ames, IA: Iowa State University Press.
2001 chapter
Chloramphenicol and derivatives, macrolides, lincosamides, and miscellaneous antibiotics
In Veterinary pharmacology and therapeutics (8th ed.) (pp. 868–897). Ames, IA: Iowa State University Press.
2001 journal article
Cytokine induction as a measure of cutaneous toxicity in primary and immortalized porcine keratinocytes exposed to jet fuels, and their relationship to normal human epidermal keratinocytes
Toxicology Letters, 119(3), 209–217.
2001 report
Dermal absorption cutting fluids
In Annual report 1R010H03669-01A2.
2001 chapter
Dermatopharmacology: drugs acting locally on the skin
In Veterinary pharmacology and therapeutics (8th ed.) (Vol. 53, pp. 1084–1104). Ames, IA: Iowa State University Press.
2001 journal article
Effect of selective lipid extraction from different body regions on epidermal barrier function
Pharmaceutical Research, 18(7), 992–998.
2001 journal article
Effects of short-term high-dose and low-dose dermal exposure to Jet A, JP-8 and JP-8+100 jet fuels
Journal of Applied Toxicology, 21(6), 485–494.
2001 journal article
Enhanced systemic tissue distribution after dermal versus intravenous 3,3 ',4,4 '-tetrachlorobiphenyl exposure: Limitedutility of radiolabel blood area under the curve and excretiondata in dermal absorption calculations and tissue exposureassessment
Toxicology and Applied Pharmacology, 177(1), 26–37.
2001 chapter
Fluoroquinolones antimicrobial drugs
In Veterinary pharmacology and therapeutics (8th ed.) (Vol. 45, pp. 898–917). Ames, IA: Iowa State University Press.
2001 journal article
Mixed effects modeling of the disposition of gentamicin across domestic animal species
Journal of Veterinary Pharmacology and Therapeutics, 24(5), 321–332.
2001 journal article
Mixture component effects on the in vitro dermal absorption of pentachlorophenol
Archives of Toxicology, 75(6), 329–334.
2001 journal article
Mixture effects of JP-8 additives on the dermal disposition of jet fuel components
Toxicology and Applied Pharmacology, 175(3), 269–281.
2001 chapter
Penicillins and related beta-Lactam antibiotics
In Veterinary pharmacology and therapeutics (8th ed.) (pp. 818–827). Ames, IA: Iowa State University Press.
2001 chapter
Pesticide disposition: dermal absorption
In Handbook of Pesticide Toxicology (2nd ed.) (pp. 515–530).
2001 journal article
Potential and problems of developing transdermal patches for veterinary applications
Advanced Drug Delivery Reviews, 50(3), 175–203.
2001 chapter
Sulfonamides
In Veterinary pharmacology and therapeutics (8th ed.) (pp. 796–817). Ames, IA: Iowa State University Press.
2001 chapter
Tetracyclines
In Veterinary pharmacology and therapeutics (8th ed.) (pp. 828–840). Ames, IA: Iowa State University Press.
2001 journal article
Use of methyl salicylate as a simulant to predict the percutaneous absorption of sulfur mustard
Journal of Applied Toxicology, 21(2), 91–99.
2000 journal article
Amoxicillin pharmacokinetics in harbor seals (Phoca vitulina) and northern elephant seals (Mirounga angustirostris) following single dose intravenous administration: implications for interspecific dose sealing
Journal of Veterinary Pharmacology and Therapeutics, 23(4), 223–228.
2000 conference paper
Basic toxicokinetic principles and methodology
Toxicokinetics and Physiologically-Based Toxicokinetics in Toxicology and Risk Assessment: Continuing Education Course Syllabus, 39th Annual Meeting of the Society of Toxicology, 39, 2–18.
2000 journal article
Comparative in vitro percutaneous absorption of nonylphenol and nonylphenol ethoxylates (NPE-4 and NPE-9) through human, porcine and rat skin
Toxicology and Industrial Health, 16(2), 49–57.
2000 journal article
Compass plots: A combination of star plot and analysis of means to visualize significant interactions in complex toxicology studies
Toxicology Methods, 10(4), 313–332.
2000 journal article
Dermal absorption and tissue disposition of 3,3',4,4'-tetrachlorobiphenyl (TCB) in an ex vivo pig model: Assessing the impact of dermal exposure variables
International Journal of Occupational and Environmental Health, 6, 127–137.
2000 journal article
Dermatotoxicokinetic modeling of p-nitrophenol and its conjugation metabolite in swine following topical and intravenous administration
Toxicological Sciences, 54(2), 284–294.
2000 journal article
Extralabel use of ivermectin and moxidectin in food animals
Journal of the American Veterinary Medical Association, 217(5), 668–671.
2000 journal article
Food safety, FARAD, and Residue Avoidance in the 6th millenium
Journal of Veterinary Pharmacology and Therapeutics, 23(Suppl 1 CD).
2000 journal article
Identification of early biomarkers of inflammation produced by keratinocytes exposed to jet fuels Jet A, JP-8, and JP-8(100)
Journal of Biochemical and Molecular Toxicology, 14(5), 231–237.
2000 journal article
Membrane transport of naphthalene and dodecane in jet fuel mixtures
Toxicology and Industrial Health, 16(6), 225–238.
2000 journal article
Methods of assessing the percutaneous absorption of volatile chemicals in isolated perfused skin: Studies with chloropentafluorobenzene and dichlorobenzene
Toxicology Methods, 10(4), 265–281.
2000 patent
Methods, systems and products for determining drug withdrawal intervals
Washington, DC: U.S. Patent and Trademark Office.
2000 journal article
Mixed effect modelling applied to the interspecies scaling of gentamicin and oxytetracycline
Journal of Veterinary Pharmacology and Therapeutics, 23(Supp.1 CD), B26.
2000 chapter
Use of antimicrobial agents in the presence of renal impairment
In Antimicrobial therapy in veterinary medicine (3rd ed.) (pp. 453–458). Ames, IA: Iowa State University Press.
2000 journal article
Use of the pig as a model to assess cutaneous toxicity and inflammation of jet fuels
Journal of Veterinary Pharmacology and Therapeutics, 23(Suppl. 1 CD), F12.
2000 journal article
Veterinary pharmacokinetics in the 21st century
Journal of Veterinary Pharmacology and Therapeutics, 23(Supp.1 CD), B4.
1999 journal article
A topical formulation containing L tyrosine does not intensify pigmentation in human skin
Journal of Applied Cosmetology, 17, 82–85.
1999 journal article
Acute renal failure in four cats treated with paromomycin
Journal of the American Veterinary Medical Association, 215(12), 1821–1823.
1999 journal article
Dermal absorption and distribution of topically dosed jet fuels jet-A, JP-8, and JP-8(100)
Toxicology and Applied Pharmacology, 160(1), 60–75.
1999 journal article
Drugs prohibited from extralabel use in food animals
Journal of the American Veterinary Medical Association, 215(1), 28–32.
1999 journal article
Estimating provisional acceptable residues for extralabel drug use in livestock
Regulatory Toxicology and Pharmacology, 29(3), 287–299.
1999 chapter
Skin toxicology
In Toxicology (pp. 439–457).
1999 journal article
The Food Animal Residue Avoidance Databank (FARAD): Past, present and future
Veterinary Clinics of North America. Food Animal Practice, 15(1), 75–88.
1998 conference paper
Frontiers in in vitro and in vivo assessment of cutaneous toxicity models for risk assessment
Continuing education course syllabus for the 37th annual meeting of the Society of Toxicology, Seattle, WA, March, 1998, (1998 Mar.).
1998 conference paper
In vitro and in vivo assessment of cutaneous toxicity models
Continuing Education Course Syllabus for the 37th Annual Meeting of the Society of Toxicology, 37.
1998 journal article
Influence of inert ingredients in pesticide formulations on dermal absorption of carbaryl
American Journal of Veterinary Research, 59(2), 168–175.
1998 conference paper
Interspecies extrapolations of data to predict drug effects
135th Annual AVMA Convention Notes, 135, 583–584.
1998 journal article
Percutaneous absorption of salicylic acid, theophylline, 2,4- dimethylamine, diethyl hexyl phthalic acid, and p-aminobenzoic acid in the isolated perfused porcine skin flap compared to man in vivo
Toxicology and Applied Pharmacology, 151(1), 159–165.
1998 chapter
Percutaneous absorption of salicylic acid, theophylline, 2,4-dimethylamine, diethly hexylphthalic acid and p-aminobenzoic acid in the isolated perfused porcine skin flap compared to man
In Percutaneous absorption: drugs, cosmetics, mechanisms, methodology (3rd ed., rev. and expanded) (pp. 571–585). New York: Marcel Dekker.
1998 conference paper
Pharmacokinetics for the clinician
Proc. 16th Annual ACVIM Forum, 16, 166–167.
1998 conference paper
Pharmacokinetics: a tool for understanding and guiding studies on drugs
Proc. 16th Annual ACVIM Forum, 16, 71–73.
1998 conference paper
Population pharmacokinetics in veterinary medicine. Introduction and overview
Proc. 11th Biennial Symp. Am. Acad. Vet. Pharmacol. Therapeutics, 66–69.
1998 journal article
Population pharmacokinetics in veterinary medicine: Potential use for therapeutic drug monitoring and prediction of tissue residues
Journal of Veterinary Pharmacology and Therapeutics, 21(3), 167–189.
1998 journal article
Population pharmacokinetics of gentamicin in horses
American Journal of Veterinary Research, 59(12), 1589–1598.
1998 journal article
Potential complications associated with normothermic lonidamine infusion and with systemic acidosis in dogs receiving lonidamine during whole body hyperthermia (WBH)
International Journal of Hyperthermia, 14(3), 271–283.
1998 journal article
Prevention of antibiotic residues in veal calves fed colostrum
Journal of the American Veterinary Medical Association, 213(1), 40–42.
1998 journal article
Primer on estimating withdrawal times after extralabel drug use
Journal of the American Veterinary Medical Association, 213(7), 966–968.
1998 journal article
Role of veterinary therapeutics in bacterial resistance development: animal and public health perspectives
Journal of the American Veterinary Medical Association, 212(8), 1209–1213.
1997 journal article
Basic principles and techniques of pharmacokinetic modeling
Journal of Zoo and Wildlife Medicine, 28(1), 3–19.
1997 journal article
Cutaneous toxicity of the benzidine dye direct red 28 applied as mechanistically-defined chemical mixtures (MDCM) in perfused porcine skin
Toxicology Letters, 93(2-3), 159–169.
1997 journal article
Electrically-assisted transdermal drug delivery
Pharmaceutical Research, 14(6), 687–697.
1997 journal article
Evidence that gonadotropin releasing hormone (GnRH) functions as a prolactin releasing factor in a teleost fish (Oreochromis mossambicus) and primary structures for three native Gn
Journal of Endocrinology, 155(1), 121–132.
1997 journal article
Extralabel use of nonsteroidal anti inflammatory drugs
Journal of the American Veterinary Medical Association, 211(7), 860–861.
1997 journal article
Extralabel use of oxytetracycline
Journal of the American Veterinary Medical Association, 211(1), 42–44.
1997 journal article
Extralabel use of tranquilizers and general anesthetics
Journal of the American Veterinary Medical Association, 211(3), 302–304.
1997 journal article
FARAD digest: breaking new ground
Journal of the American Veterinary Medical Association, 210, 633–634.
1997 journal article
Fluconazole in cats: Pharmacokinetics following intravenous and oral administration and penetration into cerebrospinal fluid, aqueous humour and pulmonary epithelial lining fluid
Journal of Veterinary Pharmacology and Therapeutics, 20(3), 181–186.
1997 journal article
Interspecies allometric analysis of the comparative pharmacokinetics of 44 drugs using the FARAD database
Journal of Veterinary Pharmacology and Therapeutics, 20, 453–463.
1997 patent
Methods of using topical agents with systematically administered active agents
Washington, DC: U.S. Patent and Trademark Office.
1997 journal article
Pentachlorophenol dermal absorption and disposition from soil in swine: Effects of occlusion and skin microorganism inhibition
Toxicology and Applied Pharmacology, 147(2), 234–246.
1997 report
Percutaneous absorption of volatile chemicals
In (NTIS report AFOSR G49620-95-1-0017) (pp. 1–23).
1997 journal article
Pharmacokinetics and ovarian-stimulatory effects of equine and human chorionic gonadotropins administered singly and in combination in the domestic cat
Biology of Reproduction, 57(2), 295–302.
1997 chapter
Pharmacology question contributor
In Review questions and answers for veterinary boards: large animal medicine and surgery (2nd ed.) (pp. 175–177). Santa Barbara, CA: Mosby-Year Book, Inc.
1997 journal article
Residue avoidance after topical application of veterinary drugs and parasiticides
Journal of the American Veterinary Medical Association, 210(9), 1288–1289.
1997 journal article
Residue avoidance after topical application of veterinary drugs and parasiticides: Erratum
Journal of the American Veterinary Medical Association, 211(3), 304.
1997 journal article
The effects of altered media flow and glucose concentration on sulfur mustard toxicity in isolated perfused skin
In Vitro Toxicology, 10(1997), 169–181.
1997 journal article
The influence of diethyl-m-toluamide (DEET) on the percutaneous absorption of permethrin and carbaryl
Toxicology and Applied Pharmacology, 144(2), 332–339.
1997 chapter
The isolated perfused porcine skin flap
In Dermatotoxicology methods the laboratory worker's vade mecum (pp. 41–50). Washington, D.C.: Taylor and Francis.
1997 chapter
Transdermal peptide delivery using electroporation
In Protein delivery: Physical systems (pp. 213–238).
1997 book
Why our food is safer through science: Fallacies of the "chemical threat"
Fuquay-Varina, NC : Research Triangle Pub.
1996 journal article
An in vitro- in vivo validation of the isolated perfused tumor and skin flap preparation as a model of cisplatin delivery to tumors
Journal of Pharmacological and Toxicological Methods, 35, 173–177.
1996 conference paper
Compartmental models of skin transport: Dominant Eigenvalues approach
1995 Proc. Biometrics Sec., Am. Stat. Assoc., 1995, 449–454.
1996 book
Comprehensive compendium of food animal drugs: the Food Animal Residue Avoidance Databank tradename file
Gainesville, FL: University of Florida Press.
1996 journal article
Cutaneous metabolism of isosorbide dinitrate after transdermal administration in isolated perfused porcine skin
International Journal of Pharmaceutics, 127, 213–217.
1996 journal article
In vitro percutaneous absorption of benzidine in complex mechanistically defined chemical mixtures
Toxicology and Applied Pharmacology, 141, 497–506.
1996 conference paper
Integrated biochemical and molecular mechanisms of sulfur mustard vesication in skin: vascular and basement membrane targets
Proceedings of the 1996 Medical Defense Bioscience Review, 977–986. Aberdeen, MD: U.S. Army Medical Research Institute of Chemical Defense.
1996 patent
Iontophoretic electrode
Washington, DC: U.S. Patent and Trademark Office.
1996 journal article
Isolated perfused porcine skin flap systems
Pharmaceutical Biotechnology, 8, 387–407.
1996 journal article
Pharmacokinetics and toxicity of oral and intravenous lonidamine in dogs
Cancer Chemotherapy and Pharmacology, 38, 129–135.
1996 journal article
Professional flexible labeling workshop II. Task force report: developing a model of a professional veterinary drug label
Journal of the American Veterinary Medical Association, 209, 83–91.
1996 journal article
Professional flexible labeling. Task force report II: Response to comments on the proposed model of a professional drug label
Journal of the American Veterinary Medical Association, 209, 268–270.
1996 journal article
Quantitative percutaneous absorption and cutaneous distribution of binary mixtures of phenol and ?u-nitrophenol in isolated perfused porcine skin
Fundamental and Applied Toxicology, 32, 233–243.
1996 chapter
The isolated perfused porcine skin flap
In Dermatotoxicology (5th) (pp. 337–351). Washington, D.C.: Taylor and Francis.
1996 chapter
The pig as a model for cutaneous pharmacology and toxicology research
In Advances in swine in biomedical research (pp. 425–458).
1996 journal article
The use of mechanistically defined chemical mixtures (MCDM) to assess mixture component effects on the percutaneous absorption and cutaneous disposition of topically-exposed chemicals. I. Studies with parathion mixtures in isolated perfused porcine skin
Toxicology and Applied Pharmacology, 141(2), 473–486.
1996 conference paper
The use of mechanistically defined chemical mixtures to quantitate parameters of chemical percutaneous absorption using a biologically relevant experimental and mathematical modeling paradigm
Proc. Table Ronde Roussel Uclaf no 85: Passage of Drugs Across Physiological Barriers (Paris), 85, 38–40.
1996 journal article
The use of mechanistically-defined chemical mixtures (MCDM) to assess mixture component effects on the percutaneous absorption and cutaneous disposition of topically-exposed chemicals. II. Development of a general dermatopharmacokinetic model for use in risk assessment
Toxicology and Applied Pharmacology, 141, 487–496.
1995 journal article
A biophysically-based dermatopharmacokinetic compartment model for quantifying percutaneous penetration and absorption of topically applied agents. I. Theory
Journal of Pharmaceutical Sciences, 84, 599–608.
1995 chapter
Aminoglycoside antibiotics
In Veterinary pharmacology and therapeutics (7th ed.) (pp. 797–819). Ames, IA: Iowa State University Press.
1995 chapter
Antifungal and antiviral drugs
In Veterinary pharmacology and therapeutics (7th ed.) (pp. 855–883). Ames, IA: Iowa State University Press.
1995 journal article
Antifungal therapy; ketoconazole and other azole derivatives
Compendium on Continuing Education for the Practicing Veterinarian, 17, 21–31.
1995 chapter
Antiseptics/disinfectants
In Veterinary pharmacology and therapeutics (7th ed.) (pp. 741–752). Ames, IA: Iowa State University Press.
1995 chapter
Chloramphenicol, erythromycin, quinolones and miscellaneous antibiotics
In Veterinary pharmacology and therapeutics (7th ed.) (pp. 820–854). Ames, IA: Iowa State University Press.
1995 chapter
Dermatopharmacology: drugs acting locally on the skin
In Veterinary pharmacology and therapeutics (7th ed.) (pp. 1050–1090). Ames, IA: Iowa State University Press.
1995 journal article
Detection of sulfur mustard (bis-2-chloroethyl sulfide) and metabolites after topical application in the isolated perfused porcine skin flap
Life Sciences (Oxford, England), 56, 1385–1394.
1995 chapter
Drug therapy during renal disease and renal failure
In Canine and feline nephrology and urology (pp. 555–572). Baltimore: Williams and Wilkins.
1995 journal article
Effect of whole body hyperthermia on lonidamine and doxorubicin pharmacokinetics and toxicity in dogs
International Journal of Hyperthermia, 11, 545–559.
1995 journal article
Effect of whole body hyperthermia on the pharmacokinetics and toxicity of lonidamine in dogs
International Journal of Hyperthermia, 11, 531–544.
1995 journal article
Enhancing or blocking effect of fenvalerate on the subsequent percutaneous absorption of pesticides in vitro
Pesticide Biochemistry and Physiology, 51, 214–219.
1995 journal article
Evaluation of protective effects of sodium thiosulfate, cysteine, niacinamide, and indomethacin on sulfur mustard-treated isolated perfused porcine skin
Chemico-Biological Interactions, 96, 249–262.
1995 book
Handbook of comparative veterinary pharmacokinetics and residues of pesticides and environmental contaminants
Boca Raton, FL: CRC Press, Inc.
1995 journal article
Isolated perfused porcine skin flap as an in vitro model for predicting transdermal pharmacokinetics
European Journal of Pharmaceutics and Biopharmaceutics, 41, 152–162.
1995 report
Mechanisms of cutaneous vesication
In N. T. I. S. (Ed.), DAMD17-92-C-2071; NTIS, ADA305800 (Vol. 161, pp. 1–161). DAMD 17-92C-2071, NTIS Report, ADA 305800.
Ed(s): Ntis
1995 chapter
Penicillins and related beta-Lactam antibiotics
In Veterinary pharmacology and therapeutics (7th ed.) (pp. 774–783). Ames: Iowa State University Press.
1995 conference paper
Pharmacology of drug compounding
Proc. Am. Assoc. Avain Pathologists Symposium on Drugs and Therapeutics for Poultry, 39–54.
1995 journal article
Piroxicam: Evidence for local delivery following topical application
European Journal of Pharmaceutics and Biopharmaceutics, 41, 175–183.
1995 journal article
Professional flexible labeling- an AAVPT perspective: part II
Journal of the American Veterinary Medical Association, 207, 876–878.
1995 personal communication
Proper use of the term model
1995 journal article
Pulsatile transdermal delivery of LHRH using electroporation: Drug delivery and skin toxicology
Journal of Controlled Release, 36, 229–233.
1995 chapter
Residues
In Veterinary pharmacology and therapeutics (7th ed.) (pp. 1148–1157). Ames, IA: Iowa State University Press.
1995 journal article
Review of the First Interactive Workshop on Professional Flexible Labeling
Journal of the American Veterinary Medical Association, 207, 865–914.
1995 chapter
Sulfonamides
In Veterinary pharmacology and therapeutics (7th ed.) (pp. 753–773). Ames, IA: Iowa State University Press.
1995 chapter
Tetracyclines
In Veterinary pharmacology and therapeutics (7th ed.) (pp. 784–796). Ames, IA: Iowa State University Press.
1995 journal article
Topical sulfur mustard induces changes in prostaglandins and interleukin-1? in isolated perfused porcine skin
In Vitro Toxicology, 8, 149–158.
1995 journal article
Toxicokinetics of topical sulfur mustard penetration, disposition, and vascular toxicity in isolated perfused porcine skin
Toxicology and Applied Pharmacology, 135, 25–34.
1994 journal article
A full-space method for predicting in vivo transdermal plasma drug profiles reflecting both cutaneous and systemic variability
Journal of Pharmaceutical Sciences, 83, 1062–1064.
1994 journal article
Determination of physicochemical properties of phenol, p-nitrophenol, acetone and ethanol relevant to quantitating their percutaneous absorption in porcine skin
Research Communications in Chemical Pathology and Pharmacology, 83, 61–75.
1994 journal article
Development and characterization of a novel skin model for cutaneous phototoxicology
Photodermatology, Photoimmunology & Photomedicine, 235–243.
1994 journal article
Effect of hyperthermia on cisplatin and carboplatin disposition in the isolated, perfused, tumor and skin flap
International Journal of Hyperthermia, 10, 563–572.
1994 journal article
Effect of whole body hyperthermia on carboplatin disposition and toxicity in dogs
International Journal of Hyperthermia, 10, 807–816.
1994 book
Handbook of comparative pharmacokinetics and residues of veterinary therapeutic drugs
In Handbook of comparative pharmacokinetics and residues of veterinary therapeutic drugs. Boca Raton, FL: CRC Press, Inc.
1994 journal article
Identification of the pathway of electrically assisted transdermal drug delivery: light and ultrastructural studies using mercuric chloride in pigs
Pharmaceutical Research, 11, 251–256.
1994 journal article
Influence of compounding on bioavailability
Journal of the American Veterinary Medical Association, 205, 226–231.
1994 journal article
Isoelectric focussing and capillary zone electrophoretic studies using luteinizing hormone releasing hormone (LHRH) and its analogues
Journal of Pharmaceutical Sciences, 83, 654–6656.
1994 conference paper
Maintaining academic creativity in industry related research
Proc. Ninth Biennial Symp. Am. Acad. Vet. Pharmacol. Therap., 159–163.
1994 report
Mechanisms of cutaneous vesication
In DAMD17-92-C-2071; NTIS, ADA283085 (Vol. 114, pp. 1–114). DAMD 17-92-C-2071, NTIS Report, ADA 283085.
1994 patent
Method and composition for increased skin concentration of active agents by iontophoresis
Washington, DC: U.S. Patent and Trademark Office.
1994 patent
Method and composition for iontophoresis
Washington, DC: U.S. Patent and Trademark Office.
1994 journal article
Percutaneous absorption, biotransformation and systemic disposition of parathion in vivo in swine. I. Comprehensive pharmacokinetic model
Drug Metabolism and Disposition, 22, 459–471.
1994 journal article
Percutaneous absorption, dermatopharmacokinetics, and related biotransformation studies of carbaryl, lindane, malathion and parathion in isolated perfused porcine skin
Toxicology (Amsterdam, Netherlands), 91, 269–280.
1994 journal article
Pharmacologic modulation of the cutaneous vasculture in the isolated perfused porcine skin flap (IPPSF)
Journal of Pharmaceutical Sciences, 83, 1682–1689.
1994 journal article
Production of 1,25 dihydroxyvitamine D3 by perfused pig skin
Journal of Investigative Dermatology, 102, 796–798.
1994 journal article
Review of the 1993 Veterinary Drug Bioequivalence Workshop
Journal of Veterinary Pharmacology and Therapeutics, 17, 85–119.
1994 journal article
Serum disappearance and urinary excretion of sulfamethoxypyridazine in goats
Revue d'Elevage Et De Medecine Veterinaire Des Pays Tropicaux, 47, 215–218.
1994 journal article
Stop worrying and eat your salad: science and technology have improved the safety of our food supply
Newsweek, 8.
1994 journal article
Transdermal iontophoretic delivery of luteinizing hormone releasing hormone (LHRH): Effect of repeated administration
Pharmaceutical Research, 11, 1000–1003.
1993 journal article
A model describing transdermal iontophoretic delivery of lidocaine incorporating consideration of cutaneous microvascular state
Journal of Pharmaceutical Sciences, 82, 1080–1084.
1993 chapter
Absorption and distribution
In Introduction to biochemical toxicology (2nd ed.) (pp. 11–48). Norwalk, CT: Appleton and Lange.
1993 chapter
Antimicrobial prophylaxis
In Disease mechanisms in small animal surgery (pp. 66–69). Philadelphia: Lea and Febiger.
1993 chapter
Biological factors in absorption and permeation
In Skin permeation: fundamentals and application (pp. 113–126). Wheaton, Il: Allured Publ. Inc.
1993 journal article
Development and characterization of an isolated and perfused tumor and skin preparation for evaluation of drug disposition
Cancer Research, 53, 101–105.
1993 journal article
Effect of humidity and occlusion on the percutaneous absorption of parathion in vitro
Pharmaceutical Research, 10, 152–155.
1993 journal article
Effect of tumor presence on cisplatin and carboplatin disposition in the isolated perfused tumor and skin flap
Cancer Chemotherapy and Pharmacology, 32, 31–38.
1993 chapter
Grafted skin and skin flaps
In Topical drug bioavailability, bioequivalence and penetration (pp. 209–221).
1993 journal article
Kidney trace metal response to combined cisplatin (CDDP) and hyperthermia
International Journal of Hyperthermia, 9, 529–537.
1993 conference paper
Studies on the pathogenesis of bis (2-chloroethyl) sulfide (HD) induced vesication in porcine skin
Proceedings of the Eighth Medical Defense Bioscience Review U.S. Army Medical Research Institute of Chemical Defense, 31–40. Aberdeen, MD: U.S. Army Medical Research Institute of Chemical Defense.
1993 conference paper
The use of isolated perfused skin models for quantitating transdermal drug delivery
Proc. 2nd Transdermal Delivery Systems Technology Symposium (Tokyo), 2, 71–86. Bunkashoin.
1993 journal article
Topical penetration of piroxicam is dependent on the distribution of the local cutaneous vasculature
Pharmaceutical Research, 10, 1326–1331.
1993 journal article
Transdermal iontophoretic peptide delivery. In vitro and In vivo studies with luteinizing hormone releasing hormone (LHRH)
Journal of Pharmaceutical Sciences, 82, 240–243.
1993 chapter
Use of antimicrobial agents in the presence of renal impairment
In Antimicrobial therapy in veterinary medicine (pp. 365–370). Ames, IA: Iowa State University Press.
1992 journal article
Cardiovascular effects and fatalities associated with intravenous administration of doxycycline to horses and ponies
Equine Veterinary Journal, 24, 41–45.
1992 journal article
Characterization of lewisite toxicity in isolated perfused skin
Toxicology and Applied Pharmacology, 116, 189–201.
1992 journal article
Cisplatin-induced loss of kidney copper and nephrotoxicity is ameliorated by single dose diethyldithiocarbamate, but not mesna
Toxicology and Applied Pharmacology, 112, 182–189.
1992 journal article
Cutaneous toxicity and absorption of paraquat in porcine skin
Toxicology and Applied Pharmacology, 115(1), 89–97.
1992 chapter
Dermal absorption and metabolism of xenobiotics in food producing animals
In Xenobiotics in food producing animals: metabolism and residues (Vol. 503, pp. 88–97).
1992 journal article
Determination of lidocaine concentrations in skin after transdermal iontophoresis: Effects of vasoactive drugs
Pharmaceutical Research, 211–214.
1992 conference paper
Educational perspectives in preparation for the 21st century : proceedings of the seventh biennial symposium, American Academy of Veterinary Pharmacology and Therapeutics, Raleigh, North Carolina, June 12-16, 1990
Conference Proceedings, 7.
1992 conference paper
Effect of vehicle and application site on absorption of chemicals through equine skin
Proceedings, 38th Annual Convention of the American Association of Equine Practitioners, 38, 725.
1992 book
Food Animal Residue Avoidance Databank trade name file: a comprehensive compendium of food animal drugs
(p. 457). Gainesville, FL: University of Florida Press.
1992 journal article
Model systems in iontophoresis- transport efficacy
Advanced Drug Delivery Reviews, 9, 265–287.
1992 chapter
New models in skin research: the isolated perfused porcine skin flap
In Health risk assessment: dermal and inhalational exposure and absorption of toxicants (pp. 439–452). Boca Raton, FL: CRC Press.
1992 journal article
Pharmacokinetic implications of changing blood flow in skin
Journal of Pharmaceutical Sciences, 81, 601–602.
1992 journal article
Practical aspects of the pharmacology of drug residue prevention in food animals
Agri-Practice, 13, 11–16.
1992 journal article
Quantitative prediction of transdermal iontophoretic delivery of arbutamine in humans using the in vitro isolated perfused porcine skin flap (IPPSF)
Journal of Pharmaceutical Sciences, 81, 504–507.
1992 conference paper
Role of veterinary pharmacologists in academia in the 1990's
Proc. Seventh Biennial Symp. Am. Acad. Vet. Pharmacol. Therap., 7, 39–42.
1992 chapter
Transdermal penetration and metabolism of organophosphate insecticides
In Organophosphates: chemistry, fate and effects (pp. 241–253).
1991 conference paper
Characterization of lewisite vesication in isolated perfused porcine skin
Proceedings of the 1991 Medical Defense Bioscience Review, 167–170. Aberdeen, MD: U.S. Army Medical Research Institute of Chemical Defense.
1991 conference paper
Characterization of the cutaneous vascular response to topically applied sulfur mustard and lewisite
Proceedings of the 1991 Medical Defense Bioscience Review, 163–166. Aberdeen, MD: U.S. Army Medical Research Institute of Chemical Defense.
1991 journal article
Comparative pharmacokinetics of aminoglycoside antibiotics
Journal of Veterinary Pharmacology and Therapeutics, 14, 1–35.
1991 journal article
Cutaneous laser Doppler velocimetry in nine animal species
American Journal of Veterinary Research, 52(12), 1960–1964.
1991 report
Cutaneous toxicity of mustard and lewisite on the isolated perfused porcine skin flap
In DAMD17-87-C-7139; NTIS, ADA254419 (pp. 1–140).
1991 journal article
Development of surgical techniques for preparation of in vitro isolated perfused porcine skin flaps for percutaneous absorption studies
American Journal of Veterinary Research, 52, 75–82.
1991 journal article
Effect of hyperthermia on the in vitro hydrolysis of melphalen
International Journal of Hyperthermia, 7, 527–529.
1991 journal article
FARAD - The Food Animal Residue Avoidance Databank
Extension Review, 62, 16.
1991 report
FARAD: Food Animal Residue Avoidance Databank
In FACTSHEET. Washington, DC: USDA Extension Service.
1991 book
Handbook of comparative pharmacokinetics and residues of veterinary antimicrobials
1991 chapter
In vitro absorption- skin flap model
In In vitro percutaneous absorption: principles, fundamentals and applications (pp. 207–222). Boca Raton, FL: CRC Press.
1991 journal article
In vivo percutaneous penetration/absorption
Pharmaceutical Research, 8, 1071–1075.
1991 chapter
Isolated perfused skin flap and skin grafting techniques
In Dermal and ocular toxicology: fundamentals and methods (pp. 297–322). Boca Raton: CRC Press.
1991 conference paper
Mustard induced vesication in isolated perfused skin: Biochemical, physiological, and morphological studies
Proceedings of the 1991 Medical Defense Bioscience Review, 159–162. Aberdeen, MD: U.S. Army Medical Research Institute of Chemical Defense.
1991 journal article
Perspectives on the information needs of the agricultural researcher of the 21st century
Advances in Library Administration and Organization, 9, 239–248.
1991 journal article
Pharmacologic principles of residue avoidance for the practitioner
Journal of the American Veterinary Medical Association, 198, 809–816.
1991 journal article
The effects of vasoactive drugs on transdermal lidocaine iontophoresis
Journal of Pharmaceutical Sciences, 80, 615–620.
1991 journal article
The isolated perfused equine skin flap: Preparation and metabolic parameters
Veterinary Surgery, 20, 424–433.
1991 journal article
The isolated perfused porcine skin flap as an in vitro model for percutaneous absorption and cutaneous toxicology
CRC Critical Reviews in Toxicology, 21, 329–344.
1991 journal article
The use of the Food Animal Residue Avoidance Databank in reducing residues
Journal of the American Veterinary Medical Association, 198, 816–819.
1990 journal article
A physiologically relevant pharmacokinetic model of xenobiotic percutaneous absorption utilizing the isolated perfused porcine skin flap (IPPSF)
Journal of Pharmaceutical Sciences, 79, 305–311.
1990 journal article
Biological factors in absorption and penetration
Cosmetics and Toiletries, 105, 85–93.
1990 report
Cutaneous toxicity of mustard and lewisite on the isolated perfused porcine skin flap
In DAMD17-87-C-7139; NTIS, ADA 229922 (pp. 1–144). NTIS.
1990 journal article
Determination of carboplatin in canine plasma by liquid chromatography with ultraviolet-visible detection and confirmation by atomic absorption spectroscopy
Journal of Chromatography. B, 527, 447–453.
1990 journal article
Effect of hyperthermia on cisplatin (CDDP) disposition to isolated perfused skin.
International Journal of Hyperthermia, 6, 923–932.
1990 journal article
Interspecies and interegional analysis of the comparative histological thickness and laser Doppler blood flow measurements at five cutaneous sites in nine species
Journal of Investigative Dermatology, 95, 582–586.
1990 journal article
Isolated perfused tumored skin flap model
Veterinary Cancer Society Newsletter, 14, 1–6.
1990 journal article
Nonuniform alteration of cis-diamminedichloroplatinum(II) tissue distribution in dogs with whole body hyperthermia
Cancer Research, 50(7), 2075.
1990 chapter
Percutaneous absorption of pesticides in the isolated perfused porcine skin flap (IPPSF)
In Advances in veterinary dermatology. Vol. 1 (pp. 299–307). London: Balliere-Tindall.
1990 journal article
Pharmacokinetics, inhibition of lymphoblast transformation and subacute oral toxicity of cyclosporine in swine
American Journal of Veterinary Research, 51, 399–403.
1990 journal article
Proceedings of the Workshop on the Acceptability and Interpretation of Dermal Developmental Toxicity Studies
Fundamental and Applied Toxicology, 14, 386–398.
1990 conference paper
Septic arthritis: use of therapeutic monitoring to optimize antibiotic therapy
Proceedings of the Annual Convention of the American Association of Equine Practitioners, 36, 125–131.
1990 conference paper
The role of FARAD in food contamination mitigation and prevention
Veterinary Pharmacology, Toxicology and Therapy in Food Producing Animals. Proceed. 4th Congress European Assoc. Vet. Pharmacol. Toxicol., 4, 255–258.
1990 journal article
Transdermal lidocaine iontophoresis in isolated perfused porcine skin
Journal of Toxicology. Cutaneous and Ocular Toxicology, 8, 493–504.
1989 chapter
Cephalosporins
In Current veterinary therapy X (Vol. 10, pp. 74–77). Philadelphia: WB Saunders Co.
1989 journal article
Definition of a physiologic pharmacokinetic model of cutaneous drug distribution using the isolated perfused porcine skin flap (IPPSF)
Journal of Pharmaceutical Sciences, 78, 550–555.
1989 journal article
Determination of doxycycline in bovine tissues and body fluids by liquid chromatography using photodiode array ultraviolet-visible detection
Journal of Pharmaceutical Sciences, 78, 44–47.
1989 journal article
Doxycycline binding to plasma albumin of several species
Journal of Veterinary Pharmacology and Therapeutics, 12, 253–260.
1989 conference paper
Effect of temperature on cisplatin (CDDP) and carboplatin (CBDCA) pharmacokinetic disposition in dogs
Conference Proceedings, 2, 499–501.
1989 journal article
Effects of tetracyclines on the kidney in cattle and dogs
Journal of the American Veterinary Medical Association, 195, 995–997.
1989 journal article
Estimation of physiological volumes in the isolated perfused porcine skin flap
Research Communications in Chemical Pathology and Pharmacology, 66, 145–158.
1989 journal article
Fatalities associated with intravenous administration of a single subtherapeutic dose of doxycycline to horses
Journal of the American Veterinary Medical Association, 195, 846–848.
1989 journal article
Percutaneous absorption and excretion of xenobiotics after topical and intravenous administration to pigs
Fundamental and Applied Toxicology, 13, 714–722.
1989 journal article
Pharmacokinetics and metabolic inertness of doxycycline in calves with mature or immature rumen function
American Journal of Veterinary Research, 50, 1329–1333.
1989 journal article
The isolated perfused porcine skin flap (IPPSF). III. Percutaneous absorption pharmacokinetics of organophosphates, steroids, benzoic acid and caffeine
Toxicology and Applied Pharmacology, 97, 324–337.
1988 conference paper
Coping with the information explosion in pharmacology: the Food Animal Residue Avoidance Databank
Proc. 6th Biennial Symp. Am. Acad. Vet. Pharmacol. Ther., 6, 82–82.
1988 conference paper
Development of an in vitro perfused skin flap model for transdermal drug delivery studies
Workshop on Transdermal Delivery of Drugs.
1988 conference paper
Development of automated clinical pharmacokinetic dosing programs for therapeutic drug monitoring in veterinary medicine
Proc. Sixth Biennial Symp. Am. Acad. Vet. Pharmacol. Therap., 6, 86–89.
1988 conference paper
Development of perfused skin models for assessing percutaneous absorption
Burroughs Wellcome Symposium on Dermal Toxicology, 28–40.
1988 journal article
Gentamicin pharmacokinetics and nephrotoxicity in naturally acquired and experimentally induced disease in dogs
Journal of the American Veterinary Medical Association, 192, 57–63.
1988 conference paper
Integration of pharmacology research and graduate training
Proc. Sixth Biennial Symp. Am. Acad. Vet. Pharmacol. Therap., 66–69.
1988 journal article
Multiple intravenous dose pharmacokinetics and residue depletion profile of gentamicin in pigs
Journal of Veterinary Pharmacology and Therapeutics, 11, 210–214.
1988 journal article
Pharmacokinetic Estimation of Therapeutic Dosage Regimens (PETDR): A software program designed to determine drug dosage regimens for veterinary applications
Journal of Veterinary Pharmacology and Therapeutics, 11, 390–396.
1988 journal article
Pharmacology and toxicology of doxycycline
Veterinary and Human Toxicology, 30, 431–443.
1988 journal article
Veterinary clinical pharmacokinetics. Part I. Fundamental concepts
Compendium on Continuing Education for the Practicing Veterinarian, 10, 24–31.
1988 journal article
Veterinary clinical pharmacokinetics. Part II. Modeling
Compendium on Continuing Education for the Practicing Veterinarian, 10, 313–328.
1987 chapter
Basic principles of antibiotic use
In Bristol veterinary handbook of antimicrobial therapy (2nd) (pp. 9–16). Princeton Junction, NJ: Veterinary Learning Systems Inc.
1987 report
Development of in vitro isolated perfused porcine skin flaps for study of percutaneous absorption of xenobiotics
In DAMD17-84-C-4103, NTIS, ADA 204615 (pp. 1–126).
1987 journal article
Dose-response studies of gentamicin nephrotoxicity in rats with experimental renal dysfunction. III. Effects of dosage reduction method.
Research Communications in Chemical Pathology and Pharmacology, 57, 301–311.
1987 chapter
Drug use in presence of liver and kidney disease
In Bristol veterinary handbook of antimicrobial therapy (2nd) (pp. 274–276). Princeton Junction, NJ: Veterinary Learning Systems Inc.
1987 journal article
Gentamicin dosing strategies for dogs with subclinical renal dysfunction
Antimicrobial Agents and Chemotherapy, 31, 1929–1934.