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2022 article
Mechanisms of toxicity and residue considerations of rodenticide exposure in food Animals-a FARAD perspective
Mercer, M. A., Davis, J. L., Riviere, J. E., Baynes, R. E., Tell, L. A., Jaberi-Douraki, M., … Lin, Z. (2022, March 1). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION.
2022 journal article
Predicting Nanoparticle Delivery to Tumors Using Machine Learning and Artificial Intelligence Approaches
INTERNATIONAL JOURNAL OF NANOMEDICINE.
2022 article
Update on withdrawal intervals following extralabel use of procaine penicillin G in cattle and swine
Halleran, J. L., Papich, M. G., Li, M., Lin, Z., Davis, J. L., Maunsell, F. P., … Foster, D. M. (2022, January 1). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION.
2021 content posted
Data-driven methodology for discovery and response to pulmonary symptomology in hypertension through AI and machine learning: Application to COVID-19 related pharmacovigilance
2021 journal article
Development and Application of an interactive Physiologically Based Pharmacokinetic (iPBPK) Model to Predict Oxytetracycline Tissue Distribution and Withdrawal Intervals in Market-Age Sheep and Goats
Toxicological Sciences.
2021 chapter
Percutaneous Absorption of Chemical Mixtures
In N. Dragićević (Ed.), Percutaneous Absorption (5th ed., pp. 305–314).
Ed(s): N. Dragićević
2021 journal article
Pulmonary adverse drug event data in hypertension with implications on COVID-19 morbidity
SCIENTIFIC REPORTS.
2020 journal article
A study to assess the correlation between plasma, oral fluid and urine concentrations of flunixin meglumine with the tissue residue depletion profile in finishing-age swine
BMC Veterinary Research, 16(1).
2020 conference paper
Development and application of an interactive physiological based pharmacokinetic (iPBPK) model interface to estimate withdrawal intervals for penicillin G in cattle and swine
The Toxicologist, 174(1), 458.
Event: 59th Society of Toxicology annual meeting & ToxExpo at Anaheim, California on March 15-19, 2020
2020 journal article
Meta-Analysis of Nanoparticle Delivery to Tumors Using a Physiologically Based Pharmacokinetic Modeling and Simulation Approach
ACS Nano, 14(3), 3075–3095.
2020 journal article
Pharmacovigilance in patients with diabetes: A data-driven analysis identifying specific RAS antagonists with adverse pulmonary safety profiles that have implications for COVID-19 morbidity and mortality
Journal of the American Pharmacists Association, 60(6), e145–e152.
2020 journal article
Physiological parameter values for physiologically based pharmacokinetic models in food-producing animals. Part 1: Cattle and Swine
The Toxicologist, 174(1), 461.
Event: 59th Society of Toxicology annual meeting & ToxExpo at Anaheim, California on March 15-19, 2020
2020 article
Physiological parameter values for physiologically based pharmacokinetic models in food-producing animals. Part I: Cattle and swine
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS.
2020 article
Physiological parameter values for physiologically based pharmacokinetic models in food-producing animals. Part II: Chicken and turkey
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS.
2020 journal article
Physiological parameter values for physiologically based pharmacokinetic models in food‐producing animals. Part III: Sheep and goat
Journal of Veterinary Pharmacology and Therapeutics, 44(4), 456–477.
2020 conference paper
Physiologically based pharmacokinetic modeling and simulation of nanoparticle delivery to tumors in mice
The Toxicologist, 174(1), 460.
Event: 59th Society of Toxicology annual meeting & ToxExpo at Anaheim, California on March 15-19, 2020
2019 journal article
An integrated experimental and physiologically based pharmacokinetic modeling study of penicillin G in heavy sows
Journal of Veterinary Pharmacology and Therapeutics, 42(4), 461–475.
2019 conference paper
Assessing delivery efficiency of nanoparticles to tumors in tumor-bearing mice using a physiologically based pharmacokinetic modeling and simulation approach
The Toxicologist, 168(1), 476–477,
Event: 58th Society of Toxicology annual meeting & ToxExpo at Baltimore, Maryland on March 10-14, 2019
2019 article
Data Science
SCIENCE BREAKTHROUGHS TO ADVANCE FOOD AND AGRICULTURAL RESEARCH BY 2030, pp. 145–164.
2019 journal article
Development and application of a population physiologically based pharmacokinetic model for florfenicol and its metabolite florfenicol amine in cattle
FOOD AND CHEMICAL TOXICOLOGY, 126, 285–294.
2019 journal article
Extralabel drug use in wildlife and game animals
Journal of the American Veterinary Medical Association, 255(5), 555–568.
2019 conference paper
Integration of Food Animal Residue Avoidance Databank (FARAD) Empirical Methods for Drug Withdrawal Interval Determination with a Mechanistic Population-Based Interactive Physiologically Based Pharmacokinetic (iPBPK) Modeling Platform: Example for Flunixin Meglumine Administration
The Toxicologist, 168(1), 191.
Event: 58th Society of Toxicology annual meeting & ToxExpo at Baltimore, Maryland on March 10-14, 2019
2019 journal article
Integration of Food Animal Residue Avoidance Databank (FARAD) empirical methods for drug withdrawal interval determination with a mechanistic population-based interactive physiologically based pharmacokinetic (iPBPK) modeling platform: example for flunixin meglumine administration
Archives of Toxicology, 93(7), 1865–1880.
2019 journal article
Making Sense of Pharmacovigilance and Drug Adverse Event Reporting: Comparative Similarity Association Analysis Using AI Machine Learning Algorithms in Dogs and Cats
Topics in Companion Animal Medicine, 37, 100366.
2019 journal article
Novel Data Sharing Agreement to Accelerate Big Data Translational Research Projects in the One Health Sphere
Topics in Companion Animal Medicine, 37, 100367.
2018 conference paper
A general physiologically-based pharmacokinetic model for gold nanoparticles of different sizes with multiple administration routes in rats
The Toxicologist, 162(1), 526.
Event: 57th Society of Toxicology annual meeting and ToxExpo at San Antonio, Texas on March 11-15, 2018
2018 chapter
Absorption, Distribution, Metabolism, and Elimination
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 8–40). Ames, Iowa: Wiley-Blackwell.
Ed(s): & M. Papich
2018 chapter
Aminoglycoside Antibiotics
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 877–902). Ames, Iowa: Wiley-Blackwell.
Ed(s): & M. Papich
2018 chapter
Antiarrhythmic Agents
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 537–552). Ames, Iowa: Wiley-Blackwell.
Ed(s): & M. Papich
2018 conference paper
Application of population physiologically-based pharmacokinetic model for penicillin G in dairy cows to facilitate food safety assessment
The Toxicologist, 162(1), 526.
Event: 57th Society of Toxicology annual meeting at San Antonio, Texas on March 11-15, 2018
2018 journal article
Automation and applications of the tolerance limit method in estimating meat withdrawal periods for veterinary drugs
Computers and Electronics in Agriculture, 146, 125–135.
2018 chapter
Chemical Residues in Tissues of Food Animals
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 1469–1480). Ames, Iowa: Wiley-Blackwell.
Ed(s): & M. Papich
2018 journal article
Consequences of fipronil exposure in egg-laying hens
Journal of the American Veterinary Medical Association, 253(1), 57–60.
2018 chapter
Dermatopharmacology: Drugs Acting Locally on the Skin
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 1278–1301). Ames, Iowa: Wiley-Blackwell.
Ed(s): & M. Papich
2018 chapter
Dosage Forms and Veterinary Feed Directives
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 1459–1464). Ames, Iowa: Wiley-Blackwell.
Ed(s): & M. Papich
2018 journal article
Editorial
Journal of Veterinary Pharmacology and Therapeutics, 41(3), 355–355.
2018 journal article
Extralabel drug use in small ruminants
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 253(8), 1001–1009.
2018 conference paper
Impact of natural compounds on dermal absorption for consumer products and their computational prediction
The Toxicologist, 162(1), 179.
Event: 57th Society of Toxicology annual meeting & ToxExpo at San Antonio, Texas on March 11-15, 2018
2018 journal article
Mathematical modeling and simulation in animal health. Part III: Using nonlinear mixed-effects to characterize and quantify variability in drug pharmacokinetics
Journal of Veterinary Pharmacology and Therapeutics, 41(2), 171–183.
2018 journal article
Modeling gold nanoparticle biodistribution after arterial infusion into perfused tissue: effects of surface coating, size and protein corona
Nanotoxicology, 12(10), 1093–1112.
2018 chapter
Pharmacokinetics
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 41–64). Ames, Iowa: Wiley-Blackwell.
Ed(s): & M. Papich
2018 journal article
Probabilistic Physiologically Based Pharmacokinetic Model for Penicillin G in Milk From Dairy Cows Following Intramammary or Intramuscular Administrations
Toxicological Sciences, 164(1), 85–100.
2018 journal article
Probabilistic risk assessment of gold nanoparticles after intravenous administration by integrating in vitro and in vivo toxicity with physiologically based pharmacokinetic modeling
Nanotoxicology, 12(5), 453–469.
2018 conference paper
Probabilistic risk assessment of gold nanoparticles by integrating in vitro and in vivo toxicity with physiologically-based pharmacokinetic modeling
The Toxicologist, 162(1), 526.
Event: 57th Society of Toxicology annual meeting and ToxExpo at San Antonio, Texas on March 11-15, 2018
2018 chapter
Tetracycline Antibiotics
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 858–876). Ames, Iowa: Wiley-Blackwell.
Ed(s): & M. Papich
2018 journal article
Variation in fluoroquinolone pharmacodynamic parameter values among isolates of two bacterial pathogens of bovine respiratory disease
Scientific Reports, 8(1).
2018 book
Veterinary Pharmacology and Therapeutics
(10th ed.). Ames, Iowa: Wiley-Blackwell.
Ed(s): & M. Papich
2018 chapter
Veterinary Pharmacology: An Introduction to the Discipline
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 3–7). Ames, Iowa: Wiley-Blackwell.
Ed(s): & M. Papich
2017 journal article
Avoiding violative flunixin meglumine residues in cattle and swine
Journal of the American Veterinary Medical Association, 250(2), 182–189.
2017 journal article
Biocorona formation on gold nanoparticles modulates human proximal tubule kidney cell uptake, cytotoxicity and gene expression
Toxicology in Vitro, 42, 150–160.
2017 journal article
Biological Surface Adsorption Index of Nanomaterials: Modelling Surface Interactions of Nanomaterials with Biomolecules
Advances in Experimental Medicine and Biology, 947, 207–253.
2017 journal article
Considerations for extralabel drug use in calves
Journal of the American Veterinary Medical Association, 250(11), 1275–1282.
2017 chapter
Dermatotoxicology: Computational approaches to predicting absorption of complex topical chemical mixtures
In S. Ekins (Ed.), Computational Toxicology (2nd ed., pp. 269–290). New York: John Wiley.
Ed(s): S. Ekins
2017 journal article
Development and application of a population physiologically based pharmacokinetic model for penicillin G in swine and cattle for food safety assessment
Food and Chemical Toxicology, 107, 74–87.
2017 journal article
Guide to FARAD resources: historical and future perspectives
Journal of the American Veterinary Medical Association, 250(10), 1131–1139.
2017 journal article
Modulation of topical chemical absorption by 14 natural compounds: a quantitative structure permeation (QSPR) analysis of components often found in topical preparations
Cutaneous and Ocular Toxicology, 36(3), 237–252.
2017 chapter
Multi-Walled Carbon Nanotube Exposure Alters Protein Expression in Human Keratinocytes
In Nanomedicine in Cancer (pp. 461–485).
2017 journal article
Nano in-vitro cellular uptake simulator (NICUS): a model to quantitate nanomaterial endocytosis kinetics and intracellular dose
The Toxicologist, 156, 303.
2017 journal article
NanoEHS beyond toxicity – focusing on biocorona
Environmental Science: Nano, 4(7), 1433–1454.
2017 journal article
Performance Assessment and Translation of Physiologically Based Pharmacokinetic Models From acslX to Berkeley Madonna, MATLAB, and R Language: Oxytetracycline and Gold Nanoparticles As Case Examples
Toxicological Sciences, 158(1), 23–35.
2017 journal article
Pharmacokinetics of Mequindox and Its Marker Residue 1,4-Bisdesoxymequindox in Swine Following Multiple Oral Gavage and Intramuscular Administration: An Experimental Study Coupled with Population Physiologically Based Pharmacokinetic Modeling
Journal of Agricultural and Food Chemistry, 65(28), 5768–5777.
2017 journal article
Surface chemistry of gold nanoparticles determines the biocorona composition impacting cellular uptake, toxicity and gene expression profiles in human endothelial cells
Nanotoxicology, 11(4), 507–519.
2017 journal article
Zinc Oxide Nanoparticle–Poly I:C RNA Complexes: Implication as Therapeutics against Experimental Melanoma
Molecular Pharmaceutics, 14(3), 614–625.
2016 journal article
A computational framework for interspecies pharmacokinetics, exposure and toxicity assessment of gold nanoparticles
Nanomedicine, 11(2), 107–119.
2016 journal article
A new voyage begins: welcoming new editors and the launching of Pharmacokinetic Reports
Journal of Veterinary Pharmacology and Therapeutics, 39, 317.
2016 journal article
A physiological based pharmacokinetic model for polyethylene glycol-coated gold nanoparticles of different sizes in adult mice
Nanotoxicology, 10, 162–172.
2016 journal article
Assessment of penetrant and vehicle mixture properties on transdermal permeability using a mixed effect pharmacokinetic model of ex vivo porcine skin
Biopharmaceutics & Drug Disposition, 37(7), 387–396.
2016 journal article
Biological and environmental surface interactions of nanomaterials: characterization, modeling, and prediction
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 9(3), e1440.
2016 conference paper
Biological surface adsorption index: environmental applications and parallel molecular dynamics simulations
Proceedings of 8th International Nanotoxicology Conference, 72.
Event: 8th International Nanotoxicology Conference
2016 conference paper
Caveats to making in vitro to in vivo and interspecies extrapolations of nanoparticle biological interactions using in silico computational modeling
The 51st Midwest Regional Meeting of the American Chemical Society, 47.
Event: 51st Midwest Regional Meeting of the American Chemical Society at Orlando, FL
2016 journal article
Estimation of tulathromycin depletion in plasma and milk after subcutaneous injection in lactating dairy goats using a nonlinear mixed-effect pharmacokinetic modeling approach
BMC Veterinary Research, 12(258).
2016 journal article
Exploring Post-Treatment Reversion of Antimicrobial Resistance in Enteric Bacteria of Food Animals as a Resistance Mitigation Strategy
Foodborne Pathogens and Disease, 13(11), 610–617.
2016 journal article
Health concerns and management of select veterinary drug residues
Food and Chemical Toxicology, 88, 112–122.
2016 journal article
Human food safety implications of variation in food animal drug metabolism
Scientific Reports, 6(27907).
2016 journal article
Influence of some plant extracts on the transdermal absorption and penetration of marker residues
Cutaneous and Ocular Toxicology, 30, 1–7.
2016 journal article
Limitation of MIC as sole metric of pharmacodynamic response across the range of antimicrobial susceptibility within a single bacterial species
Scientific Reports, 6(37907).
2016 journal article
Mathematical modeling and simulation in animal health – Part II : principles, methods, applications, and value of physiologically based pharmacokinetic modeling in veterinary medicine and food safety assessment
Journal of Veterinary Pharmacology and Therapeutics, 39(5), 421–438.
2016 journal article
Mathematical modeling and simulation in animal health. Part I: Moving beyond pharmacokinetics
Journal of Veterinary Pharmacology and Therapeutics, 39(3), 213–223.
2016 journal article
Mechanistic Toxicity Assessment of Hexahydroisohumulone in Canine Hepatocytes, Renal Proximal Tubules, Bone Marrow-Derived Mesenchymal Stem Cells, and Enterocyte-like Cells
International Journal of Veterinary Health Science & Research, 4(2), 88–103.
2016 journal article
Mechanistic toxicity assessment of hexahydroisohumulone in canine hepatocytes, renal proximal tubules, and enterocyte like-cells
The Toxicologist, 150, 487.
2016 journal article
Modulation of Chemical Dermal Absorption by 14 Natural Products: A Quantitative Structure Permeation (QSPR) Analysis of Components Often Found in Topical Cosmeceuticals
Cutaneous and Ocular Toxicology, 36(3), 237–252.
2016 journal article
Observations on macrolide resistance in field isolates collected from bovine respiratory disease cases
Veterinary Microbiology, 192, 186–193.
2016 journal article
Oxidative stress response in canine in vitro liver, kidney and intestinal models with seven potential dietary ingredients
Toxicology Letters, 241, 49–59.
2016 journal article
Pharmacokinetics and tissue elimination of flunixin in veal calves
American Journal of Veterinary Research, 77(6), 634–640.
2016 conference paper
Physiological based pharmacokinetic (PBPK) modeling of nanomaterials: Why is quantitation and anatomical / physiological reality so important?
Proceedings of 8th International Nanotoxicology Conference, 385.
Event: 8th International Nanotoxicology Conference
2016 chapter
Potential mechanism of toxicity of hexahydroisohumulone in an in vitro canine model
Presented at the WINNS 2016 – Growing Science in Pet Nutrition.
Event: WINNS 2016 – Growing Science in Pet Nutrition
2016 conference paper
Predicting and modeling in vivo nanoparticle biodistribution: caveats to making in vitro and rodent interspecies extrapolations
11th International Particle Toxicology Conference, 54.
Event: 11th International Particle Toxicology Conference
2016 journal article
Protein corona modulation of hepatocyte uptake and molecular mechanisms of gold nanoparticle toxicity
Nanotoxicology, 11(1), 64–75.
2016 journal article
Protocol for diversion of confirmed positive bulk raw milk tankers to calf ranches – A review of the Pharmacokinetics of tetracyclines and sulfonamides in veal calves
Animal Health Research Reviews, 17(2), 127–136.
2016 journal article
Quantification of nanoparticle pesticide adsorption: computational approaches based on experimental data
Nanotoxicology, 10(8), 1118–1128.
2016 journal article
Residue concerns following exposure to livestock to oil and petroleum products
Journal of the American Veterinary Medical Association, 248, 145–146.
2016 journal article
Screening and Confirmatory Analyses of Flunixin in Tissues and Bodily Fluids after Intravenous or Intramuscular Administration to Cull Dairy Cows with or without Lipopolysaccharide Challenge
Journal of Agricultural and Food Chemistry, 64(1), 336–345.
2016 chapter
The effects of vehicle mixtures on transdermal absorption: thermodynamics, mechanism, assessment and prediction
In N. Dragicevic-Curic & H. I. Maibach (Eds.), Percutaneous Penetration Enhancers Drug Penetration Into/Through the Skin: Methodology and General Considerations (pp. 95–118). New York: Springer.
Ed(s): N. Dragicevic-Curic & H. Maibach
2016 journal article
Toxicological effects of pet food ingredients on canine bone marrow-derived mesenchymal stem cells and enterocyte-like cells
Journal of Applied Toxicology, 36(2), 189–198.
2015 journal article
A Framework for Meta-Analysis of Veterinary Drug Pharmacokinetic Data Using Mixed Effect Modeling
Journal of Pharmaceutical Sciences, 104(4), 1230–1239.
2015 journal article
Canine renal proximal tubule cells as an in vitro model for toxicity assessment of pet food ingredients
The Toxicologist, 144, 490.
2015 journal article
Comparative In Vitro Cytotoxicity of 20 Potential Food Ingredients in Canine Liver, Kidney, Bone Marrow-Derived Mesenchymal Stem Cells, and Enterocyte-like Cells
Applied In Vitro Toxicology, 1(4), 276–288.
2015 journal article
Comparison of pharmacokinetics and milk elimination of flunixin in healthy cows and cows with mastitis
Journal of the American Veterinary Medical Association, 246(1), 118–125.
2015 journal article
Determination of thermodynamic solubility of active pharmaceutical ingredients for veterinary species: a new USP general chapter
Pharmacopeial Forum, 41(3).
2015 journal article
Development and Application of a Multiroute Physiologically Based Pharmacokinetic Model for Oxytetracycline in Dogs and Humans
Journal of Pharmaceutical Sciences, 104(1), 233–243.
2015 conference paper
Development of a physiologically-relevant multivariate nanoparticle molecular interaction fingerprint
Presented at the 250th American Chemical Society National Meeting, Boston, MA.
Event: 250th American Chemical Society National Meeting at Boston, MA
2015 journal article
Differential effects of some natural compounds on the transdermal absorption and penetration of caffeine and salicylic acid
International Journal of Pharmaceutics, 483(1-2), 151–157.
2015 journal article
Egg residue considerations during the treatment of backyard poultry
Journal of the American Veterinary Medical Association, 247(12), 1388–1395.
2015 journal article
Estimation of residue depletion of cyadox and its marker residue in edible tissues of pigs using physiologically based pharmacokinetic modeling
Food Additives & Contaminants: Part A, 32(12), 2002–2017.
2015 journal article
Excretory, Secretory, and Tissue Residues after Label and Extra-label Administration of Flunixin Meglumine to Saline- or Lipopolysaccharide-Exposed Dairy Cows
Journal of Agricultural and Food Chemistry, 63(19), 4893–4901.
2015 conference paper
Flunixin urine residues in culled dairy cows and its relevance to food safety and environmental concern
Presented at the 250th American Chemical Society National Meeting, Boston, MA.
Event: 250th American Chemical Society National Meeting at Boston, MA
2015 journal article
Gold and silver nanoparticle interactions with human proteins: impact and implications in biocorona formation
Journal of Materials Chemistry B, 3(10), 2075–2082.
2015 journal article
In vitro safety assessment of food ingredients in canine renal proximal tubule cells
Toxicology in Vitro, 29(2), 289–298.
2015 journal article
Interaction of silver and gold nanoparticles with protein biocorona formation and its impact on cellular toxicity
International Journal of Toxicology, 34, 78–79.
2015 journal article
Nanoparticle surface characterization and clustering through concentration-dependent surface adsorption modeling
The Toxicologist, 144, 66.
2015 journal article
Pharmacokinetics and pharmacodynamics of gamithromycin in pulmonary epithelial lining fluid in naturally occurring bovine respiratory disease in multisource commingled feedlot cattle
Journal of Veterinary Pharmacology and Therapeutics, 39(2), 157–166.
2015 journal article
Pharmacokinetics of metallic nanoparticles
WIREs Nanomedicine and Nanobiotechnology, 7(2), 189–217.
2015 journal article
Predicting Adsorption Affinities of Small Molecules on Carbon Nanotubes Using Molecular Dynamics Simulation
ACS Nano, 9(12), 11761–11774.
2015 journal article
Predicting the impact of biocorona formation kinetics on interspecies extrapolations of nanoparticle biodistribution modeling
Nanomedicine, 10(1), 25–33.
2015 journal article
Prediction and comparison of size-dependent biodistribution of polyethylene glycol-coated gold nanoparticles in adult mice: a physiologically based pharmacokinetic model
The Toxicologist, 144, 65.
2015 journal article
Quantification of vehicle mixture effects on in vitro transdermal chemical flux using a random process diffusion model
Journal of Controlled Release, 217, 74–81.
2015 journal article
Safety assessment of pet food ingredients using cryopreserved canine hepatocytes-based in vitro assays
The Toxicologist, 144, 20.
2015 journal article
Safety assessment of potential food ingredients in canine hepatocytes
Food and Chemical Toxicology, 78, 105–115.
2015 journal article
Toxicokinetic approaches to improving accuracy of drug withdrawal times in food producing animals to avoid toxic violative tissue residues
International Journal of Toxicology, 34, 78.
2014 journal article
Antimicrobial Agents in Veterinary Medicine
Journal of Veterinary Pharmacology and Therapeutics, 37(1), 1–1.
2014 chapter
Dermal Exposure and Absorption of Chemicals and Nanomaterials
In Reference Module in Biomedical Sciences.
2014 journal article
Development of a physiologically based pharmacokinetic model for flunixin in cattle (Bos taurus)
Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment, 31(9), 1506–1521.
2014 journal article
In silico models to predict dermal absorption from complex agrochemical formulations
SAR and QSAR in Environmental Research, 25(7), 565–588.
2014 journal article
In silico models to predict dermal absorption from complex agrochemical formulations
SAR and QSAR in Environmental Research, 6, 1–24.
2014 journal article
Interspecies Mixed-Effect Pharmacokinetic Modeling of Penicillin G in Cattle and Swine
Antimicrobial Agents and Chemotherapy, 58(8), 4495–4503.
2014 journal article
Interspecies allometric meta-analysis of the comparative pharmacokinetics of 85 drugs across veterinary and laboratory animal species
Journal of Veterinary Pharmacology and Therapeutics, 38(3), 214–226.
2014 journal article
Nanoparticle Surface Characterization and Clustering through Concentration-Dependent Surface Adsorption Modeling
ACS Nano, 8(9), 9446–9456.
2014 journal article
Pharmacokinetics, tissue distribution, and excretion of nomegestrol acetate in female rats
European Journal of Drug Metabolism and Pharmacokinetics, 40(4), 435–442.
2014 journal article
Prediction of formulation effects on dermal absorption of topically applied ectoparasiticides dosed in vitro on canine and porcine skin using a mixture-adjusted quantitative structure permeability relationship
Journal of Veterinary Pharmacology and Therapeutics, 37(5), 435–444.
2014 journal article
The application of allometric scaling principles to predict pharmacokinetic parameters across species
Expert Opinion on Drug Metabolism & Toxicology, 10(9), 1241–1253.
2014 journal article
development of a mixed-effect pharmacokinetic model for vehicle modulated in vitro transdermal flux of topically applied penetrants
Journal of Pharmaceutical Sciences, 103(3), 1002–1012.
2013 journal article
Assessing vehicle effects on skin absorption of non-volatile compounds using membrane-coated fiber arrays
Cutaneous and Ocular Toxicology, 32(4), 283–289.
2013 journal article
Assessing vehicle effects on skin absorption using artificial membrane assays
European Journal of Pharmaceutical Sciences, 50(5), 569–576.
2013 journal article
Comparison of ELISA and LC-MS/MS for the measurement of Flunixin plasma concentrations in beef cattle after intravenous and subcutaneous administration
Journal of Agricultural and Food Chemistry, 61(11), 2679–2686.
2013 journal article
Limitations of MIC as the sole criterion in antimicrobial drug dosage regimen design: The need for full characterization of antimicrobial pharmacodynamic profile especially for drug-resistant organisms
The Veterinary Journal, 198(1), 15–18.
2013 journal article
Modeling the effect of experimental variables on the in vitro permeation of six model compounds across porcine skin
International Journal of Pharmaceutics, 443(1-2), 58–67.
2013 journal article
Occurrence of flunixin residues in bovine milk samples from the USA
Food Additives & Contaminants: Part A, 30(9), 1513–1516.
2013 journal article
Of mice, men and nanoparticle biocoronas: are in vitro to in vivo correlations and interspecies extrapolations realistic?
Nanomedicine, 8(9), 1357–1359.
2013 journal article
Oxidative stress and dermal toxicity of iron oxide nanoparticles in vitro
Cell Biochemistry and Biophysics, 67(2), 461–476.
2013 review
Predicting skin permeability from complex vehicles
[Review of ]. Advanced Drug Delivery Reviews, 65(2), 265–277.
2013 journal article
Prediction of flunixin tissue residue concentrations in livers from diseased cattle
Food and Chemical Toxicology, 62, 876–879.
2013 journal article
Protein binding modulates the cellular uptake of silver nanoparticles into human cells: Implications for in vitro to in vivo extrapolations?
Toxicology Letters, 220(3), 286–293.
2013 journal article
Use of population pharmacokinetic modeling and Monte Carlo simulation to capture individual animal variability in the prediction of flunixin withdrawal times in cattle
Journal of Veterinary Pharmacology and Therapeutics, 36(3), 248–257.
2013 journal article
Vasomodulation Influences on the Transdermal Delivery of Ibuprofen
Journal of Pharmaceutical Sciences, 102(11), 4072–4078.
2012 journal article
Acute vascular effects of nanoparticle infusion in isolated perfused skin
Nanomedicine: Nanotechnology, Biology and Medicine, 8(4), 428–431.
2012 journal article
Challenges obtaining a biowaiver for topical veterinary dosage forms
Journal of Veterinary Pharmacology and Therapeutics, 35, 103–114.
2012 journal article
Development of a physiologically based pharmacokinetic model to predict tulathromycin distribution in goats
Journal of Veterinary Pharmacology and Therapeutics, 35(2), 121–131.
2012 journal article
Evaluation of factors important in modeling plasma concentrations of tetracycline hydrochloride administered in water in swine
American Journal of Veterinary Research, 73(10), 1641–1649.
2012 journal article
Experimental factors affecting in vitro absorption of six model compounds across porcine skin
Toxicology in Vitro, 26(7), 1191–1198.
2012 journal article
In vitro biodistribution of silver nanoparticles in isolated perfused porcine skin flaps
Journal of Applied Toxicology, 32(11), 913–919.
2012 journal article
Lack of hydroxylated fullerene toxicity after intravenous administration to female Sprague-Dawley rats
Journal of Toxicology and Environmental Health. Part A, 75(7), 367–373.
2012 journal article
Pharmacokinetics and tissue elimination of tulathromycin following subcutaneous administration in meat goats
American Journal of Veterinary Research, 73(10), 1634–1640.
2012 journal article
Plasma pharmacokinetics and milk residues of flunixin and 5-hydroxy flunixin following different routes of administration in dairy cattle
Journal of Dairy Science, 95(12), 7151–7157.
2012 journal article
Quantum dot penetration into viable human skin
Nanotoxicology, 6(2), 173–185.
2012 journal article
The effect of formulations and experimental conditions on in vitro human skin permeation—Data from updated EDETOX database
International Journal of Pharmaceutics, 434(1-2), 280–291.
2012 journal article
Tulathromycin assay validation and tissue residues after single and multiple subcutaneous injections in domestic goats (Capra aegagrus hircus)
Journal of Veterinary Pharmacology and Therapeutics, 35(2), 113–120.
2011 book
Comparative pharmacokinetics principles, techniques, and applications
2011 journal article
In vitro toxicity assessment of three hydroxylated fullerenes in human skin cells
Toxicology in Vitro, 25(8), 2105–2112.
2011 journal article
Mapping the surface adsorption forces of nanomaterials in biological systems
ACS Nano, 5(11), 9074–9081.
2011 journal article
Pet food safety: a shared concern
British Journal of Nutrition, 106, S78–84.
2011 journal article
Pharmacokinetics of tulathromycin after single and multiple subcutaneous injections in domestic goats (Capra aegagrus hircus)
Journal of Veterinary Pharmacology and Therapeutics, 34(5), 448–454.
2011 journal article
Pharmacokinetics of tulathromycin following subcutaneous administration in meat goats
Research in Veterinary Science, 90(3), 477–479.
2011 journal article
Predicting skin permeability from complex chemical mixtures: Dependency of quantitative structure permeation relationships on biology of skin model used
Toxicological Sciences, 119(1), 224–232.
2011 journal article
Safety evaluation of sunscreen formulations containing titanium dioxide and zinc oxide nanoparticles in UVB sunburned skin: An in vitro and in vivo study
Toxicological Sciences, 123(1), 264–280.
2010 journal article
A time to change: update on methods and manuscript topics appropriate for the journal of veterinary pharmacology and therapeutics
Journal of Veterinary Pharmacology and Therapeutics, 33(5), 415–415.
2010 journal article
An index for characterization of nanomaterials in biological systems
Nature Nanotechnology, 5(9), 671–675.
2010 journal article
Disposition of melamine residues in blood and milk from dairy goats exposed to an oral bolus of melamine
Food and Chemical Toxicology, 48(8-9), 2542–2546.
2010 journal article
Evaluation of perfused porcine skin as a model system to quantitate tissue distribution of fullerene nanoparticles
Toxicology Letters, 197(1), 1–6.
2010 journal article
Intrinsic biological property of colloidal fullerene nanoparticles (nC(60)): Lack of lethality after high dose exposure to human epidermal and bacterial cells
Toxicology Letters, 197(2), 128–134.
2010 journal article
Modelling the effect of mixture components on permeation through skin
International Journal of Pharmaceutics, 398(1-2), 28–32.
2010 chapter
New Technologies for Application to Veterinary Medicine
In F. Cunningham, J. Elliott, & P. Lees (Eds.), Comparative and Veterinary Pharmacology (pp. 191–210).
Ed(s): F. Cunningham, J. Elliott & P. Lees
2010 dataset
Riviere and Brooks pig skin flow-through [data file]
2010 journal article
Skin penetration and kinetics of pristine fullerenes (C-60) topically exposed in industrial organic solvents
Toxicology and Applied Pharmacology, 242(1), 29–37.
2010 journal article
Surfactant effects on skin absorption of model organic chemicals: Implications for dermal risk assessment studies
Journal of Toxicology and Environmental Health. Part A, 73(11), 725–737.
2010 journal article
Validated models for predicting skin penetration from different vehicles
European Journal of Pharmaceutical Sciences, 41(5), 612–616.
2009 journal article
A physiologically based pharmacokinetic model linking plasma protein binding interactions with drug disposition
Research in Veterinary Science, 86(2), 293–301.
2009 journal article
Comparison of Quantum Dot Biodistribution with a Blood-Flow-Limited Physiologically Based Pharmacokinetic Model
Nano Letters, 9(2), 794–799.
2009 journal article
Dermal permeation of biocides and aromatic chemicals in three generic formulations of metalworking fluids
Journal of Toxicology and Environmental Health. Part A, 72(13), 832–841.
2009 journal article
Determination of the effective dermal penetration barrier pH of porcine skin
Journal of Veterinary Pharmacology and Therapeutics, 32(4), 407–410.
2009 journal article
Elimination kinetics of tilmicosin following intramammary administration in lactating dairy cattle
Journal of the American Veterinary Medical Association, 234(2), 245–248.
2009 journal article
Interaction of nanomaterials with skin: Aspects of absorption and biodistribution
Nanotoxicology, 3(3), 188–193.
2009 article
Pharmacokinetics of nanomaterials: An overview of carbon nanotubes, fullerenes and quantum dots (vol 1, pg 26, 2008)
Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology, Vol. 1, pp. 685–685.
2009 review
Pharmacokinetics of nanomaterials: an overview of carbon nanotubes, fullerenes and quantum dots
[Review of ]. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology, 1(1), 26–34.
2009 journal article
Pharmacology of tetracycline water medication in swine
Journal of Animal Science, 87(10), 3179–3186.
2009 journal article
Selection of appropriate training set of chemicals for modeling dermal permeability using uniform coverage design
QSAR & Combinatorial Science, 28(11-12), 1478–1486.
2009 journal article
Update on drugs prohibited from extralabel use in food animals
Journal of the American Veterinary Medical Association, 235(5), 528–534.
2008 conference paper
A solvatochromatic approach to quantifying formulation effects on dermal permeability
SAR and QSAR in Environmental Research, 19(7-8), 615–630.
2008 chapter
Animal skin morphology and dermal absorption
In M. S. Roberts & K. A. Walters (Eds.), Dermal absorption and toxicity assessment (2nd ed., pp. 17–35). New York: Informa Healthcare.
Ed(s): M. Roberts & K. Walters
2008 journal article
Application of linear solvation energy relationships to a custom-made polyaniline solid-phase microextraction fiber and three commercial fibers
Journal of Chromatography. A, 1188(2), 108–117.
2008 journal article
Estimating meat withdrawal times in pigs exposed to melamine contaminated feed using a physiologically based pharmacokinetic model
Regulatory Toxicology and Pharmacology, 51(3), 324–331.
2008 journal article
FARAD digest - Extralabel use of nonsteroidal anti-inflammatory drugs in cattle
Journal of the American Veterinary Medical Association, 232(5), 697–701.
2008 journal article
Inhibition of jet fuel aliphatic hydrocarbon induced toxicity in human epidermal keratinocytes
Journal of Applied Toxicology, 28(4), 543–553.
2008 chapter
Percutaneous absorption of complex chemical mixtures
In Marzulli and Maibach's dermatotoxicology (7th ed.) (pp. 63–70). New York: Taylor and Francis.
2008 journal article
Pharmacokinetics of melamine in pigs following intravenous administration
Food and Chemical Toxicology, 46(3), 1196–1200.
2008 journal article
Quantification of chemical mixture interactions modulating dermal absorption using a multiple membrane fiber array
Chemical Research in Toxicology, 21(3), 591–599.
2008 chapter
Solvents and vehicle effects on the skin
In M. S. Roberts & K. A. Walters (Eds.), Dermal absorption and toxicity assessment. (2nd ed.) (pp. 433–447). New York: Informa Healthcare.
Ed(s): M. Roberts & K. Walters
2008 journal article
Sulfamethazine water medication pharmacokinetics and contamination in a commercial pig production unit
Journal of Food Protection, 71(3), 584–589.
2008 book
Veterinary pharmacology and therapeutics
Ames, IA: Blackwell Publishing.
2007 journal article
A system coefficient approach for quantitative assessment of the solvent effects on membrane absorption from chemical mixtures
SAR and QSAR in Environmental Research, 18(5-6), 579–593.
2007 journal article
An experimentally based approach for predicting skin permeability of chemicals and drugs using a membrane-coated fiber array
Toxicology and Applied Pharmacology, 221(3), 320–328.
2007 journal article
Biodistribution of quantum dot nanoparticles in perfused skin: Evidence of coating dependency and periodicity in arterial extraction
Nano Letters, 7(9), 2865–2870.
2007 journal article
Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework
Toxicology and Applied Pharmacology, 222, 122–128.
2007 journal article
Current update on drugs for game bird species
Journal of the American Veterinary Medical Association, 231(10), 1506–1508.
2007 chapter
Dermal toxicity
In Veterinary toxicology: basic and clinical principles (pp. 263–276).
2007 chapter
Dermatotoxicology: Computational risk assessment
In Computational toxicology: risk assessment for pharmaceutical and environmental chemicals (pp. 677–692).
2007 journal article
Managing canine obesity: a new therapeutic approach
Journal of Veterinary Pharmacology and Therapeutics, 30(Suppl.).
2007 journal article
Membrane-coated fiber array approach for predicting skin permeability of chemical mixtures from different vehicles
Toxicological Sciences, 99(1), 153–161.
2007 journal article
Naïve averaged, naïve pooled, and population pharmacokinetics of orally administered marbofloxacin in juvenile harbor seals
Journal of the American Veterinary Medical Association, 230(3), 390–395.
2007 journal article
Partitioning behavior of aromatic components in jet fuel into diverse membrane-coated fibers
Journal of Toxicology and Environmental Health. Part A, 70(22), 1879–1887.
2007 chapter
Pharmacokinetics of nanomaterials
In Nanotoxicology: characterization, dosing and health effects (pp. 127–152). New York: Informa.
2007 chapter
Physiological based pharmacokinetic modeling
In Veterinary toxicology: basic and clinical principles (pp. 42–50).
2007 journal article
Predicting dermal permeability of biocides in commercial cutting fluids using a LSER approach
Toxicology Letters, 175(1-3), 34–43.
2007 journal article
Prediction of dermal absorption from complex chemical mixtures: incorporation of vehicle effects and interactions into a QSPR framework
SAR and QSAR in Environmental Research, 18(1-2), 31–44.
2007 report
Quantitating the absorption, partitioning and toxicity of hydrocarbon components of JP-8 jet fuel
(Center for Chemical Toxicology Research and Pharmacokinetics Grant No. FA9550-04-1-0376).
2007 journal article
Regression method of the hydrophobicity for determining octanol/water partition ruler approach coefficients of very hydrophobic compounds
Chemosphere, 66(6), 1086–1093.
2007 journal article
Surface coatings determine cytotoxicity and irritation potential of quantum dot nanoparticles in epidermal keratinocytes
Journal of Investigative Dermatology, 127(1), 143–153.
2007 journal article
The future of veterinary therapeutics: A glimpse towards 2030
The Veterinary Journal, 174(3), 462–471.
2007 journal article
Variables influencing interactions of untargeted quantum dot nanoparticles with skin cells and identification of biochemical modulators
Nano Letters, 7(5), 1344–1348.
2006 journal article
A physiologically based pharmacokinetic model of organophosphate dermal absorption
Toxicological Sciences, 89(1), 188–204.
2006 journal article
Application of risk assessment and management principles to the extralabel use of drugs in food-producing animals
Journal of Veterinary Pharmacology and Therapeutics, 29(1), 5–14.
2006 book
Biological concepts and techniques in toxicology : an integrated approach
2006 journal article
Cluster analysis of the dermal permeability and stratum corneum/solvent partitioning of ten chemicals in twenty-four chemical mixtures in porcine skin
Skin Pharmacology and Physiology, 19(4), 198–206.
2006 book
Dermal absorption models in toxicology and pharmacology
(p. ). Boca Raton: Taylor Francis/CRC Press.
2006 chapter
Dermal absorption/toxicity of organophosphates and carbamates
In Toxicology of organophosphates and carbamate pesticides (pp. 411–422).
2006 journal article
Extralabel use of penicillin in food animals
Journal of the American Veterinary Medical Association, 229(9), 1401–1403.
2006 chapter
In vivo models
In Dermal absorption models in toxicology and pharmacology (pp. 47–68). New York: Taylor and Francis / CRC Press.
2006 chapter
Introduction and overview
In Biological concepts and techniques in toxicology: an integrated approach (pp. 1–3). New York: Taylor and Francis.
2006 journal article
Penetration of intact skin by quantum dots with diverse physicochemical properties
Toxicological Sciences, 91(1), 159–165.
2006 chapter
Percutaneous absorption of chemical mixtures
In Dermal absorption models in toxicology and pharmacology (pp. 281–301). New York: Taylor and Francis / CRC Press.
2006 chapter
Perfused skin models
In Dermal absorption models in toxicology and pharmacology (pp. 27–45). New York: Taylor and Francis / CRC Press.
2006 journal article
Pharmacokinetic modeling of dermal absorption
Journal of Veterinary Pharmacology and Therapeutics, 29(S1), 244–245.
2006 journal article
Pharmacokinetics of flunixin meglumine in swine after intravenous dosing
Journal of Veterinary Pharmacology and Therapeutics, 29(5), 437–440.
2006 journal article
Skin penetration, cytotoxicity, proteomic analyses, and inflammatory potential of nanomaterials; fullerenes, multi-walled carbon nanotubes and quantum dots
Journal of Veterinary Pharmacology and Therapeutics, 29(Sup. 1), 196–197.
2006 book
Tabulation of FARAD Comparative and Veterinary Pharmacokinetic Data
Ames, IA: Blackwell Publishing.
2006 journal article
Toxicity of jet fuel aliphatic and aromatic hydrocarbon mixtures on human epidermal keratinocytes: evaluation based on in vitro cytotoxicity and interleukin-8 release
Archives of Toxicology, 80(8), 508–523.
2006 journal article
Trace analysis of fullerenes in biological samples by simplified liquid-liquid extraction and high-performance liquid chromatography
Journal of Chromatography. A, 1129(2), 216–222.
2006 journal article
Use of probabilistic modeling within a physiologically based pharmacokinetic model to predict sulfamethazine residue withdrawal times in edible tissues in swine
Antimicrobial Agents and Chemotherapy, 50(7), 2344–2351.
2005 journal article
Aminoglycoside residues in food of animal origin
Journal of the American Veterinary Medical Association, 227(1), 63–66.
2005 journal article
Antidotes in food animal practice
Journal of the American Veterinary Medical Association, 226(6), 884–887.
2005 journal article
Comparative in vivo toxicity of topical JP-8 jet fuel and its individual hydrocarbon components: Identification of tridecane and tetradecane as key constituents responsible for dermal irritation
Toxicologic Pathology, 33(2), 258–266.
2005 journal article
Comparative studies on the effects of water, ethanol and water/ethanol mixtures on chemical partitioning into porcine stratum corneum and silastic membrane
Toxicology in Vitro, 19(1), 69–77.
2005 journal article
Determination of the partition coefficients and absorption kinetic parameters of chemicals in a lipophilic membrane/water system by using a membrane-coated fiber technique
European Journal of Pharmaceutical Sciences, 24(1), 15–23.
2005 journal article
Development of a physiologic-based pharmacokinetic model for estimating sulfamethazine concentrations in swine and application to prediction of violative residues in edible tissues
American Journal of Veterinary Research, 66(10), 1686–1693.
2005 journal article
Effect of JP-8 jet fuel exposure on protein expression in human keratinocyte cells in culture
Toxicology Letters, 160(1), 8–21.
2005 journal article
Effect of formulation and route of administration on tissue residues and withdrawal times
Journal of the American Veterinary Medical Association, 227(10), 1574–1577.
2005 journal article
Effect of in vivo jet fuel exposure on subsequent in vitro dermal absorption of individual aromatic and aliphatic hydrocarbon fuel constituents
Journal of Toxicology and Environmental Health. Part A, 68(9), 719–737.
2005 journal article
Effect of vehicles and sodium lauryl sulphate on xenobiotic permeability and stratum corneum partitioning in porcine skin
Toxicology (Amsterdam, Netherlands), 206(3), 325–335.
2005 journal article
Extralabel intramammary use of drugs in dairy cattle
Journal of the American Veterinary Medical Association, 226(12), 1994–1996.
2005 journal article
Membrane uptake kinetics of jet fuel aromatic hydrocarbons from aqueous solutions studied by a membrane-coated fiber technique
Toxicology Mechanisms and Methods, 15(4), 307–316.
2005 journal article
Multi-walled carbon nanotube interactions with human epidermal keratinocytes
Toxicology Letters, 155(3), 377–384.
2005 journal article
Multivariate meta-analysis of pharmacokinetic studies of ampicillin trihydrate in cattle
American Journal of Veterinary Research, 66(1), 108–112.
2005 chapter
Percutaneous absorption of chemical mixtures
In Percutaneous absorption: drugs, cosmetics, mechanisms, methodology (4th ed.) (pp. 155–163). New York: Taylor and Francis / Marcel Dekker.
2005 conference paper
Pharmacokinetic and allometric techniques used by FARAD to estimate extended withdrawal times
Proc. 14th Biennial AAVPT Symposium, 14.
2005 journal article
Pre-treatment effects of trichloroethylene on the dermal absorption of the biocide, triazine
Toxicology Letters, 159(3), 252–260.
2005 journal article
Predicting skin permeability from complex chemical mixtures
Toxicology and Applied Pharmacology, 208(2), 99–110.
2005 conference paper
The pig as a model for human skin research
Swine in Biomedical Research: Update on Animal Models. Sinclair Research Center. 56th AALAS National Meeting, 56, 17–22.
2004 journal article
A Compartment Model for the Membrane-Coated Fiber Technique Used for Determining the Absorption Parameters of Chemicals into Lipophilic Membranes
Pharmaceutical Research, 21(8), 1345–1352.
2004 journal article
A web-based decision support system to estimate extended withdrawal intervals
Computers and Electronics in Agriculture, 44(2), 145–151.
2004 journal article
Characterization of polyacrylate membrane-coated fibers used in chemical absorption studies with programmed thermal treatment and FT-IR microscopy
Analytical Chemistry, 76(14), 4245–4250.
2004 journal article
Comparative mixture effects of JP-8(100) additives on the dermal absorption and disposition of jet fuel hydrocarbons in different membrane model systems
Toxicology Letters, 150(3), 351–365.
2004 journal article
Current approved drugs for aquatic species
Journal of the American Veterinary Medical Association, 224(1), 50–51.
2004 journal article
Dose related absorption of JP-8 jet fuel hydrocarbons through porcine skin with quantitative structure permeability relationship analysis
Toxicology Mechanisms and Methods, 14(3), 159–166.
2004 journal article
Drugs approved for small ruminants
Journal of the American Veterinary Medical Association, 224(4), 520–523.
2004 journal article
Elimination kinetics of ceftiofur hydrochloride after intramammary administration in lactating dairy cows
Journal of the American Veterinary Medical Association, 224(11), 1827–1830.
2004 journal article
Feasibility of using half-life multipliers to estimate extended withdrawal intervals following the extralabel use of drugs in food-producing animals
Journal of Food Protection, 67(3), 555–560.
2004 journal article
Meta-analysis of pharmacokinetic data of veterinary drugs using the Food Animal Residue Avoidance Databank: oxytetracycline and procaine penicillin G
Journal of Veterinary Pharmacology and Therapeutics, 27(5), 343–353.
2004 journal article
Mixture additives inhibit the dermal permeation of the fatty acid, ricinoleic acid
Toxicology Letters, 147(1), 15–26.
2004 chapter
Percutaneous absorption of complex chemical mixtures
In Dermatotoxicology (6th ed.) (pp. 30–41). Boca Raton, FL: CRC Press.
2004 report
Quantitating the Percutaneous Absorption of Mechanistically-Defined Chemical Mixtures
2004 journal article
Skin toxicity of jet fuels: Ultrastructural studies and the effects of substance P
Toxicology and Applied Pharmacology, 195(3), 339–347.
2004 chapter
The isolated perfused porcine skin flap
In Dermatotoxicology (6th ed.) (pp. 564–588). Boca Raton, FL: CRC Press.
2004 journal article
Veterinary application of in vitro dissolution data and the biopharmaceutics classification system
Pharmacopeial Forum, 30, 2295–2303.
2003 journal article
A novel in-vitro technique for studying percutaneous permeation with a membrane-coated fiber and gas chromatography/mass spectrometry: Part I. Performances of the technique and determination of the permeation rates and partition coefficients of ?
Pharmaceutical Research, 20(2), 275–282.
2003 book
Comparative pharmacokinetics: principles, techniques and applications
(p. 327). Ames, IA: Blackwell Publishing (Iowa State Press).
2003 journal article
Dermal disposition of triazine in cutting fluid mixtures
Journal of Toxicology. Cutaneous and Ocular Toxicology, 22(4), 215–229.
2003 journal article
Evaluation of the advisory services provided by the Food Animal Residue Avoidance Databank
Journal of the American Veterinary Medical Association, 223(11), 1596–1598.
2003 journal article
In vitro percutaneous absorption of nonylphenol (Np) and nonylphenol ethoxylates (Npe-4 and Npe-9) in isolated perfused skin
Journal of Toxicology. Cutaneous and Ocular Toxicology, 22(1-2), 1–11.
2003 journal article
Mechanisms of skin absorption
Journal of Veterinary Pharmacology and Therapeutics, 26, 25.
2003 journal article
Percutaneous absorption of 2,6-di-tert-butyl-4-nitrophenol (DBNP) in isolated perfused porcine skin
Toxicology in Vitro, 17(3), 289–292.
2003 journal article
Percutaneous absorption of topical N,N-diethyl-m-toluamide (DEET): Effects of exposure variables and coadministered toxicants
Journal of Toxicology and Environmental Health. Part A, 66(2), 133–151.
2003 journal article
Pyridostigmine bromide modulates topical irritant-induced cytokine release from human epidermal keratinocytes and isolated perfused porcine skin
Toxicology (Amsterdam, Netherlands), 183(1-3), 15–28.
2003 journal article
The cytotoxicity of jet fuel aromatic hydrocarbons and dose-related interleukin-8 release from human epidermal keratinocytes
Archives of Toxicology, 77(7), 384–391.
2003 journal article
Toxicokinetics and Physiologically Based Toxicokinetics in Toxicology and Risk Assessment
Journal of Toxicology and Environmental Health, Part B, 6(1), 1–40.
2003 journal article
Update on FARAD food animal drug withholding recommendations
Journal of the American Veterinary Medical Association, 223(9), 1277–1278.
2002 journal article
Analysis of N,N-diethyl-m-toluamide in porcine skin perfusates using solid-phase extraction disks and reversed-phase high- performance liquid chromatography
Journal of Chromatography. B, 780(1), 45–52.
2002 journal article
Applying the biopharmaceutics classification system to veterinary pharmaceutical products Part II. Physiological considerations
Advanced Drug Delivery Reviews, 54(6), 825–850.
2002 book
Chemical food safety: A scientist's perspective
Ames, Iowa: Iowa State Press.
2002 journal article
Differential relationship between the carbon chain length of jet fuel aliphatic hydrocarbons and their ability to induce cytotoxicity vs. interleukin-8 release in human epidermal keratinocytes
Toxicological Sciences, 69(1), 226–233.
2002 journal article
Effect of chemical interactions in pentachlorophenol mixtures on skin and membrane transport
Toxicological Sciences, 69(2), 295–305.
2002 journal article
Extrapolated withdrawal-interval estimator (EWE) algorithm: A quantitative approach to establishing extralabel withdrawal times
Regulatory Toxicology and Pharmacology, 36(1), 131–137.
2002 journal article
Gulf War related exposure factors influencing topical absorption of 14C-permethrin
Toxicology Letters, 135(1-2), 61–71.
2002 journal article
Mixed-effects modeling of the interspecies pharmacokinetic scaling of oxytetracycline
Journal of Pharmaceutical Sciences, 91(2), 331–341.
2002 journal article
Physicochemical determinants of linear alkylbenzene sulfonate (LAS) disposition in skin exposed to aqueous cutting fluid mixtures
Toxicology and Industrial Health, 18(5), 237–248.
2002 journal article
Pyridostigmine bromide modulates the dermal disposition of [C- 14]permethrin
Toxicology and Applied Pharmacology, 181(3), 164–173.
2002 journal article
Systemic uptake and cutaneous disposition of pentachlorophenol in a sequential exposure scenario: Effects of skin preexposure to benzo[a] pyrene
Journal of Toxicology and Environmental Health. Part A, 65(18), 1307–1331.
2002 journal article
The use of enzyme histochemistry in detecting cutaneous toxicity of three topically applied jet fuel mixtures
Toxicology Mechanisms and Methods, 12(1), 17–34.
2002 journal article
Toxicokinetics and physiologically based toxicokinetics in toxicology and risk assessment
Journal of Toxicology and Environmental Health. Part B, Critical Reviews, 6(1), 1–40.
2001 chapter
Aminoglycoside antibiotics
In Veterinary pharmacology and therapeutics (8th ed.) (pp. 841–867). Ames, IA: Iowa State University Press.
2001 journal article
Analysis of interleukin-8 release from normal human epidermal keratinocytes exposed to aliphatic hydrocarbons: delivery of hydrocarbons to cell cultures via complexation with alpha-cyclodextrin
Toxicology in Vitro, 15(6), 663–669.
2001 chapter
Antifungal and antiviral drugs
In Veterinary Pharmacology: Therapeutics (8th ed.) (pp. 918–946). Ames, IA: Iowa State University Press.
2001 chapter
Antiseptics/disinfectants
In Veterinary Pharmacology: Therapeutics (8th ed.) (pp. 783–795). Ames, IA: Iowa State University Press.
2001 chapter
Chemical residues in tissues of food animals
In Veterinary pharmacology and therapeutics (8th ed.) (pp. 1166–1174). Ames, IA: Iowa State University Press.
2001 chapter
Chloramphenicol and derivatives, macrolides, lincosamides, and miscellaneous antibiotics
In Veterinary pharmacology and therapeutics (8th ed.) (pp. 868–897). Ames, IA: Iowa State University Press.
2001 journal article
Cytokine induction as a measure of cutaneous toxicity in primary and immortalized porcine keratinocytes exposed to jet fuels, and their relationship to normal human epidermal keratinocytes
Toxicology Letters, 119(3), 209–217.
2001 report
Dermal absorption cutting fluids
In Annual report 1R010H03669-01A2.
2001 chapter
Dermatopharmacology: drugs acting locally on the skin
In Veterinary pharmacology and therapeutics (8th ed.) (Vol. 53, pp. 1084–1104). Ames, IA: Iowa State University Press.
2001 journal article
Effect of selective lipid extraction from different body regions on epidermal barrier function
Pharmaceutical Research, 18(7), 992–998.
2001 journal article
Effects of short-term high-dose and low-dose dermal exposure to Jet A, JP-8 and JP-8 + 100 jet fuels
Journal of Applied Toxicology, 21(6), 485–494.
2001 journal article
Enhanced Systemic Tissue Distribution after Dermal versus Intravenous 3,3′,4,4′-Tetrachlorobiphenyl Exposure: Limited Utility of Radiolabel Blood Area under the Curve and Excretion Data in Dermal Absorption Calculations and Tissue Exposure Assessment
Toxicology and Applied Pharmacology, 177(1), 26–37.
2001 chapter
Fluoroquinolones antimicrobial drugs
In Veterinary pharmacology and therapeutics (8th ed.) (Vol. 45, pp. 898–917). Ames, IA: Iowa State University Press.
2001 journal article
Mixed effects modeling of the disposition of gentamicin across domestic animal species
Journal of Veterinary Pharmacology and Therapeutics, 24(5), 321–332.
2001 journal article
Mixture component effects on the in vitro dermal absorption of pentachlorophenol
Archives of Toxicology, 75(6), 329–334.
2001 journal article
Mixture effects of JP-8 additives on the dermal disposition of jet fuel components
Toxicology and Applied Pharmacology, 175(3), 269–281.
2001 chapter
Penicillins and related beta-Lactam antibiotics
In Veterinary pharmacology and therapeutics (8th ed.) (pp. 818–827). Ames, IA: Iowa State University Press.
2001 chapter
Pesticide disposition: dermal absorption
In Handbook of Pesticide Toxicology (2nd ed.) (pp. 515–530).
2001 journal article
Potential and problems of developing transdermal patches for veterinary applications
Advanced Drug Delivery Reviews, 50(3), 175–203.
2001 chapter
Sulfonamides
In Veterinary pharmacology and therapeutics (8th ed.) (pp. 796–817). Ames, IA: Iowa State University Press.
2001 chapter
Tetracyclines
In Veterinary pharmacology and therapeutics (8th ed.) (pp. 828–840). Ames, IA: Iowa State University Press.
2001 journal article
Use of methyl salicylate as a simulant to predict the percutaneous absorption of sulfur mustard
Journal of Applied Toxicology, 21(2), 91–99.
2000 journal article
Amoxicillin pharmacokinetics in harbor seals (Phoca vitulina) and northern elephant seals (Mirounga angustirostris) following single dose intravenous administration: implications for interspecific dose sealing
Journal of Veterinary Pharmacology and Therapeutics, 23(4), 223–228.
2000 conference paper
Basic toxicokinetic principles and methodology
Toxicokinetics and Physiologically-Based Toxicokinetics in Toxicology and Risk Assessment: Continuing Education Course Syllabus, 39th Annual Meeting of the Society of Toxicology, 39, 2–18.
2000 journal article
Comparative in vitro percutaneous absorption of nonylphenol and nonylphenol ethoxylates (NPE-4 and NPE-9) through human, porcine and rat skin
Toxicology and Industrial Health, 16(2), 49–57.
2000 journal article
Compass plots: A combination of star plot and analysis of means to visualize significant interactions in complex toxicology studies
Toxicology Methods, 10(4), 313–332.
2000 journal article
Dermal absorption and tissue disposition of 3,3',4,4'-tetrachlorobiphenyl (TCB) in an ex vivo pig model: Assessing the impact of dermal exposure variables
International Journal of Occupational and Environmental Health, 6, 127–137.
2000 journal article
Dermatotoxicokinetic modeling of p-nitrophenol and its conjugation metabolite in swine following topical and intravenous administration
Toxicological Sciences, 54(2), 284–294.
2000 journal article
Extralabel use of ivermectin and moxidectin in food animals
Journal of the American Veterinary Medical Association, 217(5), 668–671.
2000 journal article
Food safety, FARAD, and Residue Avoidance in the 6th millenium
Journal of Veterinary Pharmacology and Therapeutics, 23(Suppl 1 CD).
2000 journal article
Identification of early biomarkers of inflammation produced by keratinocytes exposed to jet fuels Jet A, JP-8, and JP-8(100)
Journal of Biochemical and Molecular Toxicology, 14(5), 231–237.
2000 journal article
Membrane transport of naphthalene and dodecane in jet fuel mixtures
Toxicology and Industrial Health, 16(6), 225–238.
2000 journal article
Methods of assessing the percutaneous absorption of volatile chemicals in isolated perfused skin: Studies with chloropentafluorobenzene and dichlorobenzene
Toxicology Methods, 10(4), 265–281.
2000 patent
Methods, systems and products for determining drug withdrawal intervals
Washington, DC: U.S. Patent and Trademark Office.
2000 journal article
Mixed effect modelling applied to the interspecies scaling of gentamicin and oxytetracycline
Journal of Veterinary Pharmacology and Therapeutics, 23(Supp.1 CD), B26.
2000 chapter
Use of antimicrobial agents in the presence of renal impairment
In Antimicrobial therapy in veterinary medicine (3rd ed.) (pp. 453–458). Ames, IA: Iowa State University Press.
2000 journal article
Use of the pig as a model to assess cutaneous toxicity and inflammation of jet fuels
Journal of Veterinary Pharmacology and Therapeutics, 23(Suppl. 1 CD), F12.
2000 journal article
Veterinary pharmacokinetics in the 21st century
Journal of Veterinary Pharmacology and Therapeutics, 23(Supp.1 CD), B4.
1999 journal article
A topical formulation containing L tyrosine does not intensify pigmentation in human skin
Journal of Applied Cosmetology, 17, 82–85.
1999 journal article
Acute renal failure in four cats treated with paromomycin
Journal of the American Veterinary Medical Association, 215(12), 1821–1823.
1999 journal article
Dermal Absorption and Distribution of Topically Dosed Jet Fuels Jet-A, JP-8, and JP-8(100)
Toxicology and Applied Pharmacology, 160(1), 60–75.
1999 journal article
Drugs prohibited from extralabel use in food animals
Journal of the American Veterinary Medical Association, 215(1), 28–32.
1999 journal article
Estimating provisional acceptable residues for extralabel drug use in livestock
Regulatory Toxicology and Pharmacology, 29(3), 287–299.
1999 chapter
Skin toxicology
In et al. H. Marquardt (Ed.), Toxicology (pp. 439–457).
Ed(s): e. H. Marquardt
1999 journal article
The Food Animal Residue Avoidance Databank (Farad): Past, Present and Future
Veterinary Clinics of North America: Food Animal Practice, 15(1), 75–88.
1998 journal article
Enhanced systemic tissue distribution after topical versus intravenous TCB (3,3′, 4,4′-tetrachlorobiphenyl) administered at equivalent doses: A clear example of route dependency in risk assessment
Toxicology Letters, 95, 92.
1998 conference paper
Frontiers in in vitro and in vivo assessment of cutaneous toxicity models for risk assessment
Continuing education course syllabus for the 37th annual meeting of the Society of Toxicology, Seattle, WA, March, 1998, (1998 Mar.).
1998 journal article
Impacts of cutaneous cytochrome P450 induction by benzo[a]pyrene on pentachlorophenol dermal absorption and disposition in three porcine models
Toxicology Letters, 95(Supplement 1), 97.
1998 conference paper
In vitro and in vivo assessment of cutaneous toxicity models
Continuing Education Course Syllabus for the 37th Annual Meeting of the Society of Toxicology, 37.
1998 journal article
Influence of inert ingredients in pesticide formulations on dermal absorption of carbaryl
American Journal of Veterinary Research, 59(2), 168–175.
1998 conference paper
Interspecies extrapolations of data to predict drug effects
135th Annual AVMA Convention Notes, 135, 583–584.
1998 journal article
Percutaneous Absorption of Salicylic Acid, Theophylline, 2,4-Dimethylamine, Diethyl Hexyl Phthalic Acid, andp-Aminobenzoic Acid in the Isolated Perfused Porcine Skin Flap Compared to Manin Vivo
Toxicology and Applied Pharmacology, 151(1), 159–165.
1998 chapter
Percutaneous absorption of salicylic acid, theophylline, 2,4-dimethylamine, diethly hexylphthalic acid and p-aminobenzoic acid in the isolated perfused porcine skin flap compared to man
In Percutaneous absorption: drugs, cosmetics, mechanisms, methodology (3rd ed., rev. and expanded) (pp. 571–585). New York: Marcel Dekker.
1998 conference paper
Pharmacokinetics for the clinician
Proc. 16th Annual ACVIM Forum, 16, 166–167.
1998 conference paper
Pharmacokinetics: a tool for understanding and guiding studies on drugs
Proc. 16th Annual ACVIM Forum, 16, 71–73.
1998 conference paper
Population pharmacokinetics in veterinary medicine. Introduction and overview
Proc. 11th Biennial Symp. Am. Acad. Vet. Pharmacol. Therapeutics, 66–69.
1998 journal article
Population pharmacokinetics in veterinary medicine: Potential use for therapeutic drug monitoring and prediction of tissue residues
Journal of Veterinary Pharmacology and Therapeutics, 21(3), 167–189.
1998 journal article
Population pharmacokinetics of gentamicin in horses
American Journal of Veterinary Research, 59(12), 1589–1598.
1998 journal article
Potential complications associated with normothermic lonidamine infusion and with systemic acidosis in dogs receiving lonidamine during whole body hyperthermia (WBH)
International Journal of Hyperthermia, 14(3), 271–283.
1998 journal article
Prevention of antibiotic residues in veal calves fed colostrum
Journal of the American Veterinary Medical Association, 213(1), 40–42.
1998 journal article
Primer on estimating withdrawal times after extralabel drug use
Journal of the American Veterinary Medical Association, 213(7), 966–968.
1998 journal article
Role of veterinary therapeutics in bacterial resistance development: animal and public health perspectives
Journal of the American Veterinary Medical Association, 212(8), 1209–1213.
1997 journal article
Basic principles and techniques of pharmacokinetic modeling
Journal of Zoo and Wildlife Medicine, 28(1), 3–19.
1997 journal article
Cutaneous toxicity of the benzidine dye direct red 28 applied as mechanistically-defined chemical mixtures (MDCM) in perfused porcine skin
Toxicology Letters, 93(2-3), 159–169.
1997 journal article
Electrically-assisted transdermal drug delivery
Pharmaceutical Research, 14(6), 687–697.
1997 journal article
Evidence that gonadotropin releasing hormone (GnRH) functions as a prolactin releasing factor in a teleost fish (Oreochromis mossambicus) and primary structures for three native Gn
Journal of Endocrinology, 155(1), 121–132.
1997 journal article
Extralabel use of nonsteroidal anti inflammatory drugs
Journal of the American Veterinary Medical Association, 211(7), 860–861.
1997 journal article
Extralabel use of oxytetracycline
Journal of the American Veterinary Medical Association, 211(1), 42–44.
1997 journal article
Extralabel use of tranquilizers and general anesthetics
Journal of the American Veterinary Medical Association, 211(3), 302–304.
1997 journal article
FARAD digest: breaking new ground
Journal of the American Veterinary Medical Association, 210, 633–634.
1997 journal article
Fluconazole in cats: Pharmacokinetics following intravenous and oral administration and penetration into cerebrospinal fluid, aqueous humour and pulmonary epithelial lining fluid
Journal of Veterinary Pharmacology and Therapeutics, 20(3), 181–186.
1997 journal article
Interspecies allometric analysis of the comparative pharmacokinetics of 44 drugs across veterinary and laboratory animal species
Journal of Veterinary Pharmacology and Therapeutics, 20(6), 453–463.
1997 patent
Methods of using topical agents with systematically administered active agents
Washington, DC: U.S. Patent and Trademark Office.
1997 journal article
Pentachlorophenol dermal absorption and disposition from soil in swine: Effects of occlusion and skin microorganism inhibition
Toxicology and Applied Pharmacology, 147(2), 234–246.
1997 report
Percutaneous absorption of volatile chemicals
In (NTIS report AFOSR G49620-95-1-0017) (pp. 1–23).
1997 journal article
Pharmacokinetics and ovarian-stimulatory effects of equine and human chorionic gonadotropins administered singly and in combination in the domestic cat
Biology of Reproduction, 57(2), 295–302.
1997 chapter
Pharmacology question contributor
In Review questions and answers for veterinary boards: large animal medicine and surgery (2nd ed.) (pp. 175–177). Santa Barbara, CA: Mosby-Year Book, Inc.
1997 journal article
Residue avoidance after topical application of veterinary drugs and parasiticides
Journal of the American Veterinary Medical Association, 210(9), 1288–1289.
1997 journal article
Residue avoidance after topical application of veterinary drugs and parasiticides: Erratum
Journal of the American Veterinary Medical Association, 211(3), 304.
1997 journal article
The effects of altered media flow and glucose concentration on sulfur mustard toxicity in isolated perfused skin
In Vitro Toxicology, 10(2), 169–181.
1997 journal article
The influence of diethyl-m-toluamide (DEET) on the percutaneous absorption of permethrin and carbaryl
Toxicology and Applied Pharmacology, 144(2), 332–339.
1997 chapter
The isolated perfused porcine skin flap
In Dermatotoxicology methods the laboratory worker's vade mecum (pp. 41–50). Washington, D.C.: Taylor and Francis.
1997 chapter
Transdermal peptide delivery using electroporation
In L. M. Sanders & R. W. Hendren (Eds.), Protein delivery: Physical systems (pp. 213–238).
Ed(s): . L. M. Sanders & R. Hendren
1997 book
Why our food is safer through science: Fallacies of the "chemical threat"
Fuquay-Varina, NC : Research Triangle Pub.
1996 journal article
An in vitro- in vivo validation of the isolated perfused tumor and skin flap preparation as a model of cisplatin delivery to tumors
Journal of Pharmacological and Toxicological Methods, 35, 173–177.
1996 conference paper
Compartmental models of skin transport: Dominant Eigenvalues approach
1995 Proc. Biometrics Sec., Am. Stat. Assoc., 1995, 449–454.
1996 book
Comprehensive compendium of food animal drugs: the Food Animal Residue Avoidance Databank tradename file
Gainesville, FL: University of Florida Press.
1996 journal article
Cutaneous metabolism of isosorbide dinitrate after transdermal administration in isolated perfused porcine skin
International Journal of Pharmaceutics, 127, 213–217.
1996 journal article