John Ross Jack

McDonough, C. W., Warren, H. R., Jack, J. R., Motsinger‐Reif, A. A., Armstrong, N. D., Bis, J. C., … Cooper‐DeHoff, R. M. (2021). Adverse Cardiovascular Outcomes and Antihypertensive Treatment: A Genome‐Wide Interaction Meta‐Analysis in the International Consortium for Antihypertensive Pharmacogenomics Studies. Clinical Pharmacology & Therapeutics, 110(3), 723–732. https://doi.org/10.1002/cpt.2355

Lynch, A. M., Ruterbories, L., Jack, J., Motsinger-Reif, A. A., & Hanel, R. (2020). The influence of packed cell volume versus plasma proteins on thromboelastographic variables in canine blood. JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 30(4), 418–425. https://doi.org/10.1111/vec.12979

Roell, K. R., Havener, T. M., Reif, D. M., Jack, J., McLeod, H. L., Wiltshire, T., & Motsinger-Reif, A. A. (2019). Synergistic Chemotherapy Drug Response Is a Genetic Trait in Lymphoblastoid Cell Lines. FRONTIERS IN GENETICS, 10. https://doi.org/10.3389/fgene.2019.00829

Jack, J., Small, G. W., Brown, C. C., Havener, T. M., McLeod, H. L., Motsinger-Reif, A. A., & Richards, K. L. (2018). Gene expression and linkage analysis implicate as a mediator of rituximab resistance. PHARMACOGENOMICS JOURNAL, 18(3), 467–473. https://doi.org/10.1038/tpj.2017.41

Akhtari, F. S., Havener, T. M., Fukudo, M., Jack, J. R., McLeod, H. L., Wiltshire, T., & Motsinger-Reif, A. A. (2018). The influence of Neanderthal alleles on cytotoxic response. PEERJ, 6. https://doi.org/10.7717/peerj.5691

Rotroff, D. M., Marvel, S. W., Jack, J. R., Havener, T. M., Doria, A., Shah, H. S., … Motsinger-Reif, A. A. (2017). Common genetic variants in neurobeachin (nbea) are associated with metformin drug response in individuals with type 2 diabetes in the accord clinical trial. Clinical Pharmacology & Therapeutics, Vol. 101, pp. S9–9.

Toledo, J. B., Arnold, M., Kastenmuller, G., Chang, R., Baillie, R. A., Han, X. L., … Motsinger-Reif, A. (2017). Metabolic network failures in Alzheimer's disease: A biochemical road map. Alzheimers & Dementia, 13(9), 965–984.

Jackson, J. N., Long, K. M., He, Y., Motsinger-Reif, A. A., McLeod, H. L., & Jack, J. (2016). A comparison of DMET Plus microarray and genome-wide technologies by assessing population substructure. PHARMACOGENETICS AND GENOMICS, 26(4), 147–153. https://doi.org/10.1097/fpc.0000000000000200

Shah, I., Setzer, R. W., Jack, J., Houck, K. A., Judson, R. S., Knudsen, T. B., … Kavlock, R. J. (2016). Using ToxCast (TM) data to reconstruct dynamic cell state trajectories and estimate toxicological points of departure. Environmental Health Perspectives, 124(7), 910–919.

Jack, J., Havener, T. M., McLeod, H. L., Motsinger-Reif, A. A., & Foster, M. (2015). Evaluating the role of admixture in cancer therapy via in vitro drug response and multivariate genome-wide associations. PHARMACOGENOMICS, 16(13), 1451–1463. https://doi.org/10.2217/pgs.15.85

Abdo, N., Xia, M., Brown, C. C., Kosyk, O., Huang, R., Sakamuru, S., … Wright, F. A. (2015). Population-Based in Vitro Hazard and Concentration-Response Assessment of Chemicals: The 1000 Genomes High-Throughput Screening Study. ENVIRONMENTAL HEALTH PERSPECTIVES, 123(5), 458–466. https://doi.org/10.1289/ehp.1408775

Che, R. L., Jack, J. R., Motsinger-Reif, A. A., & Brown, C. C. (2014). An adaptive permutation approach for genome-wide association study: Evaluation and recommendations for use. Biodata Mining, 7.

Hertz, D. L., Roy, S., Jack, J., Motsinger-Reif, A. A., Drobish, A., Clark, L. S., … McLeod, H. L. (2014). Genetic heterogeneity beyond CYP2C8*3 does not explain differential sensitivity to paclitaxel-induced neuropathy. BREAST CANCER RESEARCH AND TREATMENT, 145(1), 245–254. https://doi.org/10.1007/s10549-014-2910-1

Brown, C. C., Havener, T. M., Medina, M. W., Jack, J. R., Krauss, R. M., McLeod, H. L., & Motsinger-Reif, A. A. (2014). Genome-wide association and pharmacological profiling of 29 anticancer agents using lymphoblastoid cell lines. PHARMACOGENOMICS, 15(2), 137–146. https://doi.org/10.2217/pgs.13.213

Jack, J., Rotroff, D., & Motsinger-Reif, A. (2014). Lymphoblastoid Cell Lines Models of Drug Response: Successes and Lessons from this Pharmacogenomic Model. CURRENT MOLECULAR MEDICINE, 14(7), 833–840. https://doi.org/10.2174/1566524014666140811113946

Huang, W., Massouras, A., Inoue, Y., Peiffer, J., Ramia, M., Tarone, A. M., … Highnam, G. (2014). Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines. Genome Research, 24(7), 1193–1208.

Rotroff, D., Jack, J., Campbell, N., Clark, S., & Motsinger-Reif, A. A. (2014). PGxClean: a quality control GUI for the Affymetrix DMET chip and other candidate gene studies with non-biallelic alleles. Biodata Mining, 7.

Jack, J. R., Motsinger-Reif, A. A., Koutros, S., Alavanja, M. C., Beane Freeman, L. E., & Hoppin, J. A. (2014). Single-Nucleotide Polymorphism Data Support the General Unrelatedness of the Males in the Agricultural Health Study. Cancer Epidemiology Biomarkers & Prevention, 23(10), 2192–2195. https://doi.org/10.1158/1055-9965.epi-14-0276