Jeffrey R Sommer

Works (23)

Updated: July 19th, 2023 21:17

2022 article

The impact of undernutrition on KNDy (kisspeptin/neurokinin B/dynorphin) neurons in female lambs

Harlow, K. L., Griesgraber, M. J., Seman, A. D., Shuping, S. L., Sommer, J. R., Griffith, E. H., … Nestor, C. C. (2022, May 17). JOURNAL OF NEUROENDOCRINOLOGY, Vol. 34.

By: K. Harlow n, M. Griesgraber*, A. Seman*, S. Shuping n, J. Sommer n, E. Griffith n, S. Hileman*, C. Nestor n

co-author countries: United States of America 🇺🇸
author keywords: dynorphin; kisspeptin; LH; neurokinin B; undernutrition; xxxx; fx1
MeSH headings : Animals; Arcuate Nucleus of Hypothalamus / metabolism; Body Weight; Dynorphins / metabolism; Female; Gonadotropin-Releasing Hormone / metabolism; Kisspeptins / metabolism; Malnutrition / metabolism; Neurokinin B / metabolism; Neurons / metabolism; RNA, Messenger / metabolism; Sheep
Sources: Web Of Science, ORCID
Added: April 14, 2022

2021 journal article

Evidence That Agouti-Related Peptide May Directly Regulate Kisspeptin Neurons in Male Sheep

METABOLITES, 11(3).

By: C. Merkley, S. Shuping, J. Sommer & C. Nestor

Sources: Web Of Science, ORCID
Added: April 5, 2021

2021 journal article

Evidence that pubertal status impacts kisspeptin/neurokinin B/dynorphin neurons in the gilt(dagger)

BIOLOGY OF REPRODUCTION, 105(6), 1533–1544.

By: K. Harlow n, A. Renwick n, S. Shuping n, J. Sommer n, C. Lents*, M. Knauer n, C. Nestor n

co-author countries: United States of America 🇺🇸
author keywords: kisspeptin; NKB; dynorphin; swine; puberty
MeSH headings : Animals; Arcuate Nucleus of Hypothalamus / metabolism; Dynorphins / metabolism; Female; Kisspeptins / metabolism; Neurokinin B / metabolism; Neurons / physiology; Sexual Maturation; Sus scrofa / physiology
Sources: Web Of Science, ORCID
Added: April 18, 2022

2020 article

Effects of genetic selection for early puberty on the hypothalamic-pituitary-ovarian axis in gilts

Harlow, K. L., Renwick, A., Shuping, S., Sommer, J., Knauer, M., & Nestor, C. (2020, November). JOURNAL OF ANIMAL SCIENCE, Vol. 98, pp. 212–212.

By: K. Harlow n, A. Renwick n, S. Shuping n, J. Sommer n, M. Knauer n & C. Nestor n

co-author countries: United States of America 🇺🇸
author keywords: puberty; gilt; neuroendocrine
Sources: Web Of Science, ORCID
Added: February 8, 2021

2020 article

miRNAs explain the variation in muscle and blood transcriptomes of beef calves born from dams with or without energy restriction during late gestation

Carvalho, E. B., Sanglard, L. P., Nascimento, M., Moriel, P., Sommer, J., Merrill, M., … Serao, N. (2020, November). JOURNAL OF ANIMAL SCIENCE, Vol. 98, pp. 165–165.

co-author countries: Brazil 🇧🇷 United States of America 🇺🇸
author keywords: Fetal-programming; maternal nutrition; post-transcriptional regulation
Sources: Web Of Science, ORCID
Added: February 8, 2021

2019 article

Genes and functions associated with tolerance to fescue toxicosis in Angus cows

Khanal, P., Sanglard, L. P., Mayberry, K., Sommer, J., Poore, M. H., Poole, D. H., & Serao, N. V. L. (2019, July). JOURNAL OF ANIMAL SCIENCE, Vol. 97, pp. 167–167.

By: P. Khanal n, L. Sanglard*, K. Mayberry n, J. Sommer n, M. Poore n, D. Poole n, N. Serao*

co-author countries: United States of America 🇺🇸
author keywords: fescue toxicosis; differentially expressed genes; tolerance
Source: Web Of Science
Added: August 12, 2019

2018 journal article

High mobility group A2 (HMGA2) deficiency in pigs leads to dwarfism, abnormal fetal resource allocation, and cryptorchidism

Proceedings of the National Academy of Sciences, 115(21), 5420–5425.

By: J. Chung n, X. Zhang n, B. Collins n, R. Sper n, K. Gleason n, S. Simpson n, S. Koh n, J. Sommer n ...

co-author countries: United States of America 🇺🇸
author keywords: HMGA2; dwarfism; swine; gene editing; organ size
MeSH headings : Animals; Cryptorchidism / etiology; Cryptorchidism / pathology; Dwarfism / etiology; Dwarfism / pathology; Female; Fetal Diseases / etiology; Fetal Diseases / pathology; Genotype; HMGA2 Protein / deficiency; HMGA2 Protein / genetics; Litter Size; Male; Nuclear Transfer Techniques / veterinary; Pregnancy; Reproduction; Swine; Swine Diseases / etiology; Swine Diseases / pathology
Sources: Web Of Science, Crossref
Added: August 6, 2018

2018 journal article

Impact of energy restriction during late gestation on the muscle and blood transcriptome of beef calves after preconditioning

BMC Genomics, 19(1).

co-author countries: Brazil 🇧🇷 United States of America 🇺🇸
author keywords: RNA-seq; Fetal development; Fetal programming; Gene expression
MeSH headings : Animal Nutritional Physiological Phenomena; Animals; Cattle / blood; Cattle / genetics; Cattle / growth & development; Cattle / metabolism; Female; Gene Regulatory Networks; Male; Muscle, Skeletal / metabolism; Pregnancy; Transcriptome
Sources: Web Of Science, Crossref, ORCID
Added: October 16, 2018

2017 journal article

Supplementation of Maternal Diets with Docosahexaenoic Acid and Methylating Vitamins Impacts Growth and Development of Fetuses from Malnourished Gilts

Current Developments in Nutrition, 2(3).

By: H. Lima n, X. Lin n, S. Jacobi n, C. Man n, J. Sommer n, W. Flowers n, A. Blikslager n, L. Gonzalez n, J. Odle n

co-author countries: United States of America 🇺🇸

Contributors: H. Lima n, X. Lin n, S. Jacobi n, C. Man n, J. Sommer n, W. Flowers n, A. Blikslager n, L. Gonzalez n, J. Odle n

author keywords: choline; B-vitamins; epigenetics; intrauterine growth restriction; nutrient restriction; low birth weight
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2016 journal article

Effect of Plant Species, Fertilizer Acidity/Basicity, and Fertilizer Concentration on pH of Soilless Root Substrate

HORTSCIENCE, 51(12), 1596–1601.

By: K. Jeong, P. Nelson, C. Niedziela & D. Dickey

author keywords: alkalinity; electrical conductivity; root media
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Cloning, characterization, and expression analysis of the pig (Sus scrofa) C1q tumor necrosis factor-related protein-5 gene

Molecular Vision, 18(12-14), 92–102.

By: J. Sommer, V. Chavali, S. Simpson, R. Ayyagari & R. Petters

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Transgenic Stra8-EYFP pigs: a model for developing male germ cell technologies

TRANSGENIC RESEARCH, 21(2), 383–392.

By: J. Sommer n, L. Jackson n, S. Simpson n, E. Collins n, J. Piedrahita n & R. Petters n

co-author countries: United States of America 🇺🇸
author keywords: Pig; Transgenic; Stra8; Spermatogonia; Marker gene
MeSH headings : Adaptor Proteins, Signal Transducing; Animals; Animals, Genetically Modified / genetics; Animals, Genetically Modified / metabolism; Blotting, Western; Cells, Cultured; Cloning, Molecular; Fibroblasts / cytology; Fibroblasts / drug effects; Fibroblasts / metabolism; Gene Expression Regulation, Developmental; Genes, Reporter; Germ Cells / cytology; Germ Cells / metabolism; Homeodomain Proteins / genetics; Homeodomain Proteins / metabolism; Immunohistochemistry; Luminescent Proteins / genetics; Luminescent Proteins / metabolism; Male; Mice; Microscopy, Fluorescence / methods; Mitochondria / genetics; Mitochondria / metabolism; Nuclear Transfer Techniques; Plasmids / genetics; Plasmids / metabolism; Promoter Regions, Genetic; Proteins / genetics; Proteins / metabolism; Swine; Testis / cytology; Testis / metabolism; Transfection; Transgenes; Tretinoin / pharmacology
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Phenotypic stability of Pro347Leu rhodopsin transgenic pigs as indicated by photoreceptor cell degeneration

TRANSGENIC RESEARCH, 20(6), 1391–1395.

By: J. Sommer n, F. Wong* & R. Petters n

co-author countries: United States of America 🇺🇸
author keywords: Transgenic; Pig; Rhodopsin; Phenotype
MeSH headings : Age Factors; Animals; Animals, Genetically Modified / genetics; Animals, Genetically Modified / metabolism; Eosine Yellowish-(YS) / metabolism; Eye / pathology; Female; Hematoxylin / metabolism; Inbreeding; Inheritance Patterns; Male; Phenotype; Photoreceptor Cells, Vertebrate / metabolism; Photoreceptor Cells, Vertebrate / pathology; Retina / metabolism; Retina / pathology; Retinal Degeneration / pathology; Rhodopsin / genetics; Rhodopsin / metabolism; Staining and Labeling; Swine / genetics; Swine / metabolism; Transgenes
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Production of ELOVL4 transgenic pigs: a large animal model for Stargardt-like macular degeneration

British Journal of Ophthalmology, 95(12), 1749–1754.

By: J. Sommer n, J. Estrada n, E. Collins n, M. Bedell*, C. Alexander n, Z. Yang*, G. Hughes*, B. Mir n ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Animals, Genetically Modified; Disease Models, Animal; Electroretinography; Eye Proteins / biosynthesis; Eye Proteins / genetics; Gene Deletion; Immunohistochemistry; Macular Degeneration / metabolism; Macular Degeneration / pathology; Macular Degeneration / physiopathology; Membrane Proteins / biosynthesis; Membrane Proteins / genetics; Microscopy, Fluorescence; Mutation; Retina / metabolism; Retina / pathology; Retina / physiopathology; Swine
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2010 journal article

Identification of a Promoter for the Human C1q-Tumor Necrosis Factor-Related Protein-5 Gene Associated with Late-Onset Retinal Degeneration

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 51(11), 5499–5507.

By: V. Chavali*, J. Sommer n, R. Petters n & R. Ayyagari*

co-author countries: United States of America 🇺🇸
MeSH headings : 3' Untranslated Regions / genetics; Animals; Base Sequence; Blotting, Western; Cell Line; Collagen / genetics; Fluorescent Antibody Technique, Indirect; Gene Amplification; Gene Expression Regulation / physiology; Humans; Membrane Proteins / genetics; Molecular Sequence Data; Plasmids; Promoter Regions, Genetic / genetics; Retinal Degeneration / genetics; Retinal Pigment Epithelium / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Transfection
Source: Web Of Science
Added: August 6, 2018

2008 article

Successful cloning of the Yucatan minipig using commercial/occidental breeds as oocyte donors and embryo recipients

Estrada, J. L., Collins, B., York, A., Bischoff, S., Sommer, J., Tsai, S., … Piedrahita, J. A. (2008, June). CLONING AND STEM CELLS, Vol. 10, pp. 287–296.

By: J. Estrada n, B. Collins n, A. York n, S. Bischoff n, J. Sommer n, S. Tsai n, R. Petters n, J. Piedrahita n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Cell Line; Cloning, Organism / methods; Fibroblasts / cytology; Microsatellite Repeats; Nuclear Transfer Techniques; Oocytes / physiology; Sus scrofa; Swine; Swine, Miniature / embryology
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Swine generated by somatic cell nuclear transfer have increased incidence of intrauterine growth restriction (IUGR)

CLONING AND STEM CELLS, 9(2), 229–236.

By: J. Estrada n, J. Sommer n, B. Collins n, B. Mir n, A. Martin n, A. York n, R. Petters n, J. Piedrahita n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Birth Weight / physiology; Fetal Growth Retardation; Insemination, Artificial; Litter Size / physiology; Nuclear Transfer Techniques; Swine
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Synchronization and superovulation of mature cycling gilts for the collection of pronuclear stage embryos

ANIMAL REPRODUCTION SCIENCE, 100(3-4), 402–410.

By: J. Sommer n, E. Collins n, J. Estrada n & R. Petters n

co-author countries: United States of America 🇺🇸
author keywords: gilt; superovulation; estrous synchronization; pronuclear stage embryo; PG600 (R); prostaglandin F-2 alpha; transgenic
MeSH headings : Animals; Chorionic Gonadotropin / pharmacology; Dinoprost / analogs & derivatives; Dinoprost / pharmacology; Embryo, Mammalian; Estrous Cycle; Estrus Synchronization / methods; Female; Superovulation / drug effects; Superovulation / physiology; Swine / physiology
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Reporter system for the detection of in vivo gene conversion - Changing colors from blue to green using GFP variants

MOLECULAR BIOTECHNOLOGY, 33(2), 115–121.

By: J. Sommer n, O. Aiderson, G. Laible* & R. Petters n

co-author countries: New Zealand 🇳🇿 United States of America 🇺🇸
author keywords: gene conversion; marker; GFP; BFP; oligonucleotide; phosphorothioated; transfection
MeSH headings : Amino Acid Sequence; Animals; Base Sequence; CHO Cells; Clone Cells; Color; Cricetinae; Cricetulus; Gene Conversion / genetics; Genes, Reporter; Genetic Techniques; Green Fluorescent Proteins / genetics; Green Fluorescent Proteins / metabolism; Luminescent Proteins / chemistry; Luminescent Proteins / genetics; Molecular Sequence Data; Mutation / genetics; Oligonucleotides / genetics; Plasmids / genetics; Transfection
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Conditional induction of ovulation in mice

BIOLOGY OF REPRODUCTION, 73(4), 681–687.

By: P. Su n, J. Wu n, . Sommer n, A. Gore n, R. Petters n & W. Miller n

co-author countries: United States of America 🇺🇸
author keywords: assisted reproductive technology; anterior pituitary; follicle-stimulating hormone; gene regulation; ovulation
MeSH headings : Animals; Cells, Cultured; Doxycycline / pharmacology; Female; Follicle Stimulating Hormone / blood; Follicle Stimulating Hormone / genetics; Follicle Stimulating Hormone, beta Subunit / genetics; Follicle Stimulating Hormone, beta Subunit / metabolism; Genetic Engineering / methods; Male; Mice; Mice, Transgenic; Ovary / drug effects; Ovary / physiology; Ovulation / drug effects; Ovulation / genetics; Ovulation / physiology; Ovulation Induction / methods; Superovulation / genetics
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Conservation and regeneration of transgenic lines of swine by semen cryopreservation and artificial insemination

Lab Animal, 31(1), 25–31.

By: J. Sommer, E. Collins, T. Neiding, K. Rozeboom, F. Wong & R. Petters

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Transgenic animals as models for human disease

TRANSGENIC RESEARCH, 9(4-5), 347–351.

By: R. Petters n & . Sommer n

co-author countries: United States of America 🇺🇸
author keywords: transgenic animals; models of disease; homologous recombination
MeSH headings : Animals; Animals, Genetically Modified / genetics; Disease Models, Animal; Genetic Techniques; Genetic Vectors; Humans
Source: Web Of Science
Added: August 6, 2018

1997 journal article

Genetically engineered large animal model for studying cone photoreceptor survival and degeneration in retinitis pigmentosa

NATURE BIOTECHNOLOGY, 15(10), 965–970.

By: R. Petters n, C. Alexander n, K. Wells n, E. Collins n, . Sommer n, M. Blanton n, G. Rojas n, Y. Hao* ...

co-author countries: United States of America 🇺🇸
author keywords: transgenic swine; retinal degeneration; rhodopsin mutation; night blindness; eye disease
MeSH headings : Animals; Animals, Genetically Modified; Blotting, Southern; Disease Models, Animal; Electroretinography; Embryo Transfer; Gene Expression Regulation / genetics; Genetic Engineering; Microscopy, Electron; Molecular Sequence Data; Phenotype; Polymerase Chain Reaction; Retina / pathology; Retina / physiopathology; Retina / ultrastructure; Retinal Cone Photoreceptor Cells / physiopathology; Retinal Cone Photoreceptor Cells / ultrastructure; Retinal Degeneration / physiopathology; Retinitis Pigmentosa / genetics; Retinitis Pigmentosa / physiopathology; Rhodopsin / chemistry; Rhodopsin / genetics; Swine / embryology; Swine / genetics; Transgenes
Source: Web Of Science
Added: August 6, 2018

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