2005 article

Inactivation of Penicillin G in Milk Using Hydrogen Peroxide

Hanway, W. H., Hansen, A. P., Anderson, K. L., Lyman, R. L., & Rushing, J. E. (2005, February 1). Journal of Dairy Science.

By: W. Hanway n, A. Hansen n, K. Anderson n, R. Lyman n & J. Rushing n

author keywords: milk; penicillin; antibiotic; hydrogen peroxide
MeSH headings : Animals; Drug Residues / analysis; Food Handling / methods; Hot Temperature; Hydrogen Peroxide / administration & dosage; Hydrogen Peroxide / pharmacology; Milk / chemistry; Penicillin G / analysis; Penicillin G / antagonists & inhibitors
topics (OpenAlex): Antibiotic Resistance in Bacteria; Antibiotics Pharmacokinetics and Efficacy; Salmonella and Campylobacter epidemiology
TL;DR: The 0.34% concentration of hydrogen peroxide was the most effective, inactivating penicillin G to a level well below the safe level of 5 ppb with the pasteurized heat treatment, with or without incubation. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2001 article

Potential for Milk Containing Penicillin G or Amoxicillin to Cause Residues in Calves

Musser, J. M. B., Anderson, K. L., Rushing, J. E., & Moats, W. A. (2001, January 1). Journal of Dairy Science.

By: J. Musser n, K. Anderson n, J. Rushing n & W. Moats*

author keywords: penicillin; amoxicillin; residues; calves
MeSH headings : Amoxicillin / analysis; Animal Feed / analysis; Animals; Cattle / metabolism; Chromatography, High Pressure Liquid; Drug Residues; Kidney / chemistry; Liver / chemistry; Male; Metabolic Clearance Rate; Milk / chemistry; Muscles / chemistry; Penicillin G / analysis
topics (OpenAlex): Antibiotics Pharmacokinetics and Efficacy; Antibiotic Resistance in Bacteria; Microbial infections and disease research
TL;DR: It is indicated that calves fed milk with amoxicillin or penicillin G could possibly have violative residues if slaughtered within 24 h after feeding. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2000 article

Conversion of Cephapirin to Deacetylcephapirin in Milk and Tissues of Treated Animals

Moats, W. A., Anderson, K. L., Rushing, J. E., & Buckley, S. (2000, January 27). Journal of Agricultural and Food Chemistry.

By: W. Moats*, K. Anderson n, J. Rushing n & S. Buckley*

author keywords: cephapirin; deacetylcephapirin; determination; liquid chromatography; beta-lactam screening tests; milk tissues
MeSH headings : Animals; Cattle; Cephalosporins / metabolism; Cephalosporins / therapeutic use; Cephapirin / analogs & derivatives; Cephapirin / metabolism; Cephapirin / therapeutic use; Chromatography, Liquid; Female; Kidney / chemistry; Mastitis, Bovine / drug therapy; Milk / metabolism; Muscles / chemistry
topics (OpenAlex): Milk Quality and Mastitis in Dairy Cows; Microbial infections and disease research; Polyamine Metabolism and Applications
TL;DR: When a calf was treated with cephapirin by intramuscular injection, the compound was almost completely converted to DACEP in tissues, and the deacetyl form must be considered in the determination of residues in treated animals. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Detection of milk antibiotic residues by use of screening tests and liquid chromatography after intramammary administration of amoxicillin or penicillin G in cows with clinical mastitis

American Journal of Veterinary Research, 59(9), 1096–1100.

By: K. Anderson, W. Moats, J. Rushing & J. O'Carroll

Source: NC State University Libraries
Added: August 6, 2018

1998 article

Heat Resistance of Alicyclobacillus acidoterrestris Spores as Affected by Various pH Values and Organic Acids

Pontius, A. J., Rushing, J. E., & Foegeding, P. M. (1998, January 1). Journal of Food Protection, Vol. 61, pp. 41–46.

By: A. Pontius n, J. Rushing n & P. Foegeding n

MeSH headings : Bacillaceae / isolation & purification; Bacillaceae / physiology; Beverages / microbiology; Carboxylic Acids / pharmacology; Food Contamination / prevention & control; Food Microbiology; Fruit / microbiology; Hot Temperature; Hydrogen-Ion Concentration; Spores, Bacterial / growth & development
topics (OpenAlex): Microbial Inactivation Methods; Bacillus and Francisella bacterial research; Bacteriophages and microbial interactions
TL;DR: The models generated from this research can be used to determine adequate thermal processes, accounting for the acid type, pH, and temperature, to destroy A. acidoterrestris spores in beverages, since this organism is able to survive the typical hot-fill and hold process currently used to process fruit juice. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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