John S House

C/EBP beta deficiency enhances the keratinocyte innate immune response to direct activators of cytosolic pattern recognition receptors

INNATE IMMUNITY, 29(1-2), 14–24.

ToxicR: A computational platform in R for computational toxicology and dose–response analyses

Computational Toxicology, 25, 100259.

143-OR: Mapping Genetic Determinants of Blood Glucose Control in the Action to Control Cardiovascular Risk in Diabetes Study Group (ACCORD)

Diabetes, 71(Supplement_1).

Abstract PR011: Characterization of the precancerous and cancer microenvironment in a zebrafish sarcoma model

Clinical Cancer Research, 28(18_Supplement), PR011–PR011.

Adrenal Stress Hormone Regulation of Hepatic Homeostatic Function After an Acute Ozone Exposure in Wistar-Kyoto Male Rats

Toxicological Sciences, 189(1), 73–90.

Clomifene and Assisted Reproductive Technology in Humans Are Associated with Sex-Specific Offspring Epigenetic Alterations in Imprinted Control Regions

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(18).

Comparison of National Vulnerability Indices Used by the Centers for Disease Control and Prevention for the COVID-19 Response

Public Health Reports, 137(4), 803–812.

Genomic map of candidate human imprint control regions: the imprintome

Jima, D. D., Skaar, D. A., Planchart, A., Motsinger-Reif, A., Cevik, S. E., Park, S. S., … Hoyo, C. (2022, June 25). EPIGENETICS, Vol. 6.

Grouping of UVCB Substances with Dose-Response Transcriptomics Data from Human Cell-Based Assays

ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 39(3), 388–404.

LBMON114 Enrichment Of Rare Sequence Variants In Genes That Communicate Metabolic Signals To The GnRH System In Hypothalamic Amenorrhea

Journal of the Endocrine Society, 6(Supplement_1), A466–A467.

Longitudinal Serological Surveillance for COVID-19 Antibodies after Infection and Vaccination

Microbiology Spectrum, 10(5).

Maternal Mediterranean Diet Adherence and Its Associations with Maternal Prenatal Stressors and Child Growth

CURRENT DEVELOPMENTS IN NUTRITION, 6(11).

Maternal Periconceptional Stressors, Mediterranean Diet Adherence, and Child Outcomes

Current Developments in Nutrition, 6, 650.

Questionnaire-Based Polyexposure Assessment Outperforms Polygenic Scores for Classification of Type 2 Diabetes in a Multiancestry Cohort

Diabetes Care, 11, dc220295.

Questionnaire-based exposome-wide association studies (ExWAS) reveal expected and novel risk factors associated with cardiovascular outcomes in the Personalized Environment and Genes Study

Environmental Research, 212, 113463.

Social isolation exacerbates acute ozone inhalation induced pulmonary and systemic health outcomes

Toxicology and Applied Pharmacology, 457, 116295.

Stress Drivers of Glucose Dynamics during Ozone Exposure Measured Using Radiotelemetry in Rats

Environmental Health Perspectives, 130(12).

Adverse Cardiovascular Outcomes and Antihypertensive Treatment: A Genome‐Wide Interaction Meta‐Analysis in the International Consortium for Antihypertensive Pharmacogenomics Studies

Clinical Pharmacology & Therapeutics, 110(3), 723–732.

Associations between maternal obesity, gestational cytokine levels and child obesity in the NEST cohort

PEDIATRIC OBESITY, 16(7).

Glucose dynamics during ozone exposure measured using radiotelemetry: Stress drivers

Henriquez, A. R., Snow, S. J., Jackson, T. W., House, J. S., Motsinger-Reif, A. A., Ward-Caviness, C. K., … Kodavanti, U. P. (2021, December 9). (Vol. 12). Vol. 12.

Grouping of UVCB Substances with New Approach Methodologies (NAMs) Data

ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 38(1), 123–137.

High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs

PLOS GENETICS, 17(8).

Lrp1 regulation of pulmonary function follow-up of human GWAS in mice

American Journal of Respiratory Cell and Molecular Biology, 64(3), 368–378.

Periconceptional Maternal Diet Characterized by High Glycemic Loading Is Associated with Offspring Behavior in NEST

Nutrients, 13(9), 3180.

Peripheral metabolic effects of ozone exposure in healthy and diabetic rats on normal or high-cholesterol diet

Toxicology and Applied Pharmacology, 415, 115427.

The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring County-Level Vulnerability Using Visualization, Statistical Modeling, and Machine Learning

Marvel, S. W., House, J. S., Wheeler, M., Song, K., Zhou, Y.-H., Wright, F. A., … Reif, D. M. (2021, January).

The Role of Hepatic Vagal Tone in Ozone-Induced Metabolic Dysfunction in the Liver

Toxicological Sciences, 181(2), 229–245.

Associations between Maternal Cadmium Exposure with Risk of Preterm Birth and Low after Birth Weight Effect of Mediterranean Diet Adherence on Affected Prenatal Outcomes

TOXICS, 8(4).

Fibrate pharmacogenomics: Expanding past the genome

Pharmacogenomics, 21(4), 293–306.

Low-Dose Silver Nanoparticle Surface Chemistry and Temporal Effects on Gene Expression in Human Liver Cells

SMALL, 16(21).

The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring county-level vulnerability using visualization, statistical modeling, and machine learning

MedRxiv, Vol. 8.

Tissue-Engineered Bone Tumor as a Reproducible Human in Vitro Model for Studies of Anticancer Drugs

TOXICOLOGICAL SCIENCES, 173(1), 65–76.

C/EBP beta suppresses keratinocyte autonomous type 1 IFN response and p53 to increase cell survival and susceptibility to UVB-induced skin cancer

CARCINOGENESIS, 40(9), 1099–1109.

Cadmium exposure and MEG3 methylation differences between Whites and African Americans in the NEST Cohort

Environmental Epigenetics, 5(3).

Grouping of complex substances using analytical chemistry data: A framework for quantitative evaluation and visualization

PLOS ONE, 14(10).

Multi-dimensional in vitro bioactivity profiling for grouping of glycol ethers

REGULATORY TOXICOLOGY AND PHARMACOLOGY, 101, 91–102.

Necroptosis mediators RIPK3 and MLKL suppress intracellular Listeria replication independently of host cell killing

JOURNAL OF CELL BIOLOGY, 218(6), 1994–2005.

Ozone-Induced Dysregulation of Neuroendocrine Axes Requires Adrenal-Derived Stress Hormones

TOXICOLOGICAL SCIENCES, 172(1), 38–50.

Population-based toxicity screening in human induced pluripotent stem cell-derived cardiomyocytes

Toxicology and Applied Pharmacology, 381.

A Human Population-Based Organotypic In Vitro Model for Cardiotoxicity Screening

ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 35(4), 441–452.

C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event

Cell Death & Disease, 9(11).

Periconceptional maternal mediterranean diet is associated with favorable offspring behaviors and altered CpG methylation of imprinted genes

Frontiers in Cell and Developmental Biology, 6(SEP), 107.

Population-based dose-response analysis of liver transcriptional response to trichloroethylene in mouse

MAMMALIAN GENOME, 29(1-2), 168–181.

Technology Transfer of the Microphysiological Systems: A Case Study of the Human Proximal Tubule Tissue Chip

SCIENTIFIC REPORTS, 8(1).

A pipeline for high-throughput concentration response modeling of gene expression for toxicogenomics

Frontiers in Genetics, 8(NOV).

Adrenal-derived stress hormones modulate ozone-induced lung injury and inflammation

TOXICOLOGY AND APPLIED PHARMACOLOGY, 329, 249–258.

Early-life farm exposures and adult asthma and atopy in the Agricultural Lung Health Study

Journal of Allergy and Clinical Immunology, 140(1), 249–256.e14.

Raw milk consumption and other early-life farm exposures and adult pulmonary function in the Agricultural Lung Health Study

Thorax, 73(3), 279–282.

Vagal innervation is required for pulmonary function phenotype in htr4 ^–/– mice

American Journal of Physiology - Lung Cellular and Molecular Physiology, 312(4), L520–L530.

Genetic variation in HTR4 and lung function: GWAS follow-up in mouse.

FASEB Journal, 29(1), 323–335.

Quantitative Polymerase Chain Reaction Analysis of the Mouse Cyp2j Subfamily: Tissue Distribution and Regulation.

Drug Metabolism and Disposition, 43(8), 1169–1180.

ADAM19 and HTR4 variants and pulmonary function: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.

Circulation: Cardiovascular Genetics, 7(3), 350–358.

C/EBP alpha Expression Is Downregulated in Human Nonmelanoma Skin Cancers and Inactivation of C/EBP alpha Confers Susceptibility to UVB-Induced Skin Squamous Cell Carcinomas

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 131(6), 1339–1346.

C/EBP alpha and C/EBP beta Are Required for Sebocyte Differentiation and Stratified Squamous Differentiation in Adult Mouse Skin

PLOS ONE, 5(3).

C/EBP beta represses p53 to promote cell survival downstream of DNA damage independent of oncogenic Ras and p19(Arf)

CELL DEATH AND DIFFERENTIATION, 15(11), 1734–1744.