@article{son_wu_dou_fujita_cao_liu_lindsey_2023, title={Article Tethered Indoxyl-Glucuronides for Enzymatically Triggered Cross-Linking}, volume={28}, ISSN={["1420-3049"]}, DOI={10.3390/molecules28104143}, abstractNote={Indoxyl-glucuronides, upon treatment with β-glucuronidase under physiological conditions, are well known to afford the corresponding indigoid dye via oxidative dimerization. Here, seven indoxyl-glucuronide target compounds have been prepared along with 22 intermediates. Of the target compounds, four contain a conjugatable handle (azido-PEG, hydroxy-PEG, or BCN) attached to the indoxyl moiety, while three are isomers that include a PEG-ethynyl group at the 5-, 6-, or 7-position. All seven target compounds have been examined in indigoid-forming reactions upon treatment with β-glucuronidase from two different sources and rat liver tritosomes. Taken together, the results suggest the utility of tethered indoxyl-glucuronides for use in bioconjugation chemistry with a chromogenic readout under physiological conditions.}, number={10}, journal={MOLECULES}, author={Son, Juno and Wu, Zhiyuan and Dou, Jinghuai and Fujita, Hikaru and Cao, Phuong-Lien Doan and Liu, Qihui and Lindsey, Jonathan S.}, year={2023}, month={May} } @article{sato_wu_dou_son_lindsey_2023, title={Indoxyl-glucosides bearing tethers for enzymatically triggered cross-linking}, volume={47}, ISSN={["1369-9261"]}, DOI={10.1039/d2nj06267d}, abstractNote={Tethered indoxyl-glucosides upon treatment with β-glucosidase under physiological conditions afford the corresponding indigoid dye via oxidative dimerization.}, number={17}, journal={NEW JOURNAL OF CHEMISTRY}, author={Sato, Daisuke and Wu, Zhiyuan and Dou, Jinghuai and Son, Juno and Lindsey, Jonathan S. S.}, year={2023}, month={May}, pages={8223–8242} }