TAK1, MAP3K7, inflammatory signaling
2024 article
TAK1 inhibition translocates pore-forming proteins, MLKL and gasdermins into mitochondria to generate reactive oxygen species
Gonzalez-Calderon, R., Lopez-Perez, W., Sai, K., & Ninomiya-Tsuji, J. (2024, March). JOURNAL OF BIOLOGICAL CHEMISTRY, Vol. 300, pp. S555–S555.
2024 article
The Mechanism and Roles of TAK1 hyperactivation in the Alzheimer's Disease Mouse Model
Nakanishi-Hester, A., Sai, K., & Ninomiya-Tsuji, J. (2024, March). JOURNAL OF BIOLOGICAL CHEMISTRY, Vol. 300, pp. S556–S556.
2023 journal article
Aberrantly activated TAK1 links neuroinflammation and neuronal loss in Alzheimer?s disease mouse models
JOURNAL OF CELL SCIENCE, 136(6).
2021 journal article
TAK1 inhibition elicits mitochondrial ROS to block intracellular bacterial colonization
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 118(25).
Contributors: W. López-Pérez n, K. Sai n, Y. Sakamachi n, C. Parsons n, S. Kathariou n & n
2019 journal article
Coordinating Tissue Regeneration Through Transforming Growth Factor-beta Activated Kinase 1 Inactivation and Reactivation
STEM CELLS, 37(6), 766–778.
Contributors: H. Hsieh, S. Agarwal *, D. Cholok *, S. Loder *, K. Kaneko, A. Huber *, M. Chung *, K. Ranganathan *
2019 journal article
Necroptosis mediators RIPK3 and MLKL suppress intracellular Listeria replication independently of host cell killing
JOURNAL OF CELL BIOLOGY, 218(6), 1994–2005.
Contributors: K. Sai n, C. Parsons n, J. House n , S. Kathariou n & n
2018 journal article
Compound mutations in Bmpr1a and Tak1 synergize facial deformities via increased cell death
GENESIS, 56(3).
Contributors: X. Liu *, S. Hayano *, H. Pan*, M. Inagaki n, n , H. Sun *, Y. Mishina *
2017 journal article
Erratum: Noncanonical cell death program independent of caspase activation cascade and necroptotic modules is elicited by loss of TGFβ-activated kinase 1
Scientific Reports, 7(1).
2017 journal article
Noncanocial cell death program independent of caspase activation cascade and necroptotic modules is elicited by loss of TGF beta-activated kinase 1
SCIENTIFIC REPORTS, 7(1).
Contributors: S. Mihaly n, Y. Sakamachi n, n & S. Morioka n
2017 journal article
TAK1 regulates resident macrophages by protecting lysosomal integrity
CELL DEATH & DISEASE, 8(2).
Contributors: Y. Sakamachi n, S. Morioka n, S. Mihaly n, G. Takaesu n, J. Foley *, M. Fessler *, n
2016 journal article
TAK1 Regulates the Nrf2 Antioxidant System Through Modulating p62/SQSTM1
ANTIOXIDANTS & REDOX SIGNALING, 25(17), 953–964.
Contributors: K. Hashimoto n, A. Simmons*, R. Kajino-Sakamoto*, Y. Tsuji n & n
2016 journal article
TAK1 determines susceptibility to endoplasmic reticulum stress and leptin resistance in the hypothalamus
Journal of Cell Science, 129(9), 1855–1865.
Contributors: K. Sai n, S. Morioka n, G. Takaesu n, N. Muthusamy n, H. Ghashghaei n, H. Hanafusa *, K. Matsumoto *, n
2016 journal article
TAK1 regulates Paneth cell integrity partly through blocking necroptosis
CELL DEATH & DISEASE, 7(4).
Contributors: A. Simmons n, R. Kajino-Sakamoto n & n
2016 journal article
TAK1 regulates hepatic lipid homeostasis through SREBP
ONCOGENE, 35(29), 3829–3838.
Contributors: S. Morioka n, K. Sai n, E. Omori n, Y. Ikeda n, K. Matsumoto * & n
2014 journal article
Activated Macrophage Survival Is Coordinated by TAK1 Binding Proteins
PLOS ONE, 9(4).
Contributors: S. Mihaly n, S. Morioka n, n & G. Takaesu n
2014 journal article
TAK1 Binding Protein 2 Is Essential for Liver Protection from Stressors
PLOS ONE, 9(2).
Contributors: Y. Ikeda n, S. Morioka n, K. Matsumoto * & n
2014 review
TAK1 control of cell death
[Review of ]. CELL DEATH AND DIFFERENTIATION, 21(11), 1667–1676.
Contributors: S. Mihaly n, n & S. Morioka n
2014 journal article
TAK1 kinase switches cell fate from apoptosis to necrosis following TNF stimulation
The Journal of Cell Biology, 204(4), 607–623.
Contributors: S. Morioka n, P. Broglie n, Omori, Y. Ikeda n, G. Takaesu n, K. Matsumoto *, n
2014 journal article
Tak1, Smad4 and Trim33 redundantly mediate TGF-beta 3 signaling during palate development
DEVELOPMENTAL BIOLOGY, 398(2), 231–241.
Contributors: J. Lane*, K. Yumoto*, M. Azhar *, n , M. Inagaki n, Y. Hu*, C. Deng *, J. Kim *, Y. Mishina *, V. Kaartinen *
2013 journal article
Kinase-Independent Feedback of the TAK1/TAB1 Complex on BCL10 Turnover and NF-kappa B Activation
MOLECULAR AND CELLULAR BIOLOGY, 33(6), 1149–1163.
Contributors: M. Moreno-García*, K. Sommer *, H. Rincon-Arano*, M. Brault*, n , L. Matesic *, D. Rawlings *
2013 journal article
TGF-beta-activated Kinase 1 (Tak1) Mediates Agonist-induced Smad Activation and Linker Region Phosphorylation in Embryonic Craniofacial Neural Crest-derived Cells
JOURNAL OF BIOLOGICAL CHEMISTRY, 288(19), 13467–13480.
Contributors: K. Yumoto*, P. Thomas*, J. Lane*, K. Matsuzaki*, M. Inagaki n, n , G. Scott*, M. Ray*
2012 journal article
Epithelial transforming growth factor -activated kinase 1 (TAK1) is activated through two independent mechanisms and regulates reactive oxygen species
Proceedings of the National Academy of Sciences, 109(9), 3365–3370.
Contributors: E. Omori n, M. Inagaki n, Y. Mishina *, K. Matsumoto * & n
2012 journal article
TAK1 (MAP3K7) Signaling Regulates Hematopoietic Stem Cells through TNF-Dependent and -Independent Mechanisms
PLoS ONE, 7(11), e51073.
Contributors: G. Takaesu *, M. Inagaki n, K. Takubo *, Y. Mishina *, P. Hess n , G. Dean n, A. Yoshimura *, K. Matsumoto *, T. Suda *, n
Ed(s): M. Tjwa
2012 journal article
TAK1 kinase signaling regulates embryonic angiogenesis by modulating endothelial cell survival and migration
Blood, 120(18), 3846–3857.
Contributors: S. Morioka n, M. Inagaki n, Y. Komatsu *, Y. Mishina *, K. Matsumoto * & n
2011 journal article
Inhibition of autophagy by TAB2 and TAB3
EMBO JOURNAL, 30(24), 4908–4920.
Contributors: A. Criollo *, M. Niso-Santano *, S. Malik *, M. Michaud*, E. Morselli *, G. Mariño *, S. Lachkar *, A. Arkhipenko *
2011 journal article
Non-canonical beta-catenin degradation mediates reactive oxygen species-induced epidermal cell death
ONCOGENE, 30(30), 3336–3344.
Contributors: E. Omori n, K. Matsumoto * & n
2010 journal article
Ablation of TAK1 Upregulates Reactive Oxygen Species and Selectively Kills Tumor Cells
Cancer Research, 70(21), 8417–8425.
Contributors: E. Omori n, K. Matsumoto n, S. Zhu n, R. Smart n & n
2010 journal article
Regulation of Genotoxic Stress Response by Homeodomain-interacting Protein Kinase 2 through Phosphorylation of Cyclic AMP Response Element-binding Protein at Serine 271
MOLECULAR BIOLOGY OF THE CELL, 21(16), 2966–2974.
Contributors: K. Sakamoto n, B. Huang n, K. Iwasaki n, K. Hailemariam n, n & Y. Tsuji n
2010 journal article
TGF-β–Activated Kinase 1 Signaling Maintains Intestinal Integrity by Preventing Accumulation of Reactive Oxygen Species in the Intestinal Epithelium
The Journal of Immunology, 185(8), 4729–4737.
Contributors: R. Kajino-Sakamoto n, E. Omori n, P. Nighot n, A. Blikslager n , K. Matsumoto * & n
2009 journal article
Intestinal Epithelial-Derived TAK1 Signaling Is Essential for Cytoprotection against Chemical-Induced Colitis
PLOS ONE, 4(2).
Contributors: J. Kim n, R. Kajino-Sakamoto n, E. Omori n, C. Jobin * & n
2009 journal article
TAK1 kinase determines TRAIL sensitivity by modulating reactive oxygen species and cIAP
ONCOGENE, 28(23), 2257–2265.
Contributors: S. Morioka*, E. Omori n, T. Kajino *, R. Kajino-Sakamoto n, K. Matsumoto * & n
2009 journal article
Transforming Growth Factor beta-activated Kinase 1 (TAK1) Kinase Adaptor, TAK1-binding Protein 2, Plays Dual Roles in TAK1 Signaling by Recruiting Both an Activator and an Inhibitor of TAK1 Kinase in Tumor Necrosis Factor Signaling Pathway
JOURNAL OF BIOLOGICAL CHEMISTRY, 285(4), 2333–2339.
Contributors: P. Broglie n, K. Matsumoto *, S. Akira *, D. Brautigan * & n
2008 journal article
203 TAK1 Is Essential for Intestinal Epithelial Cell Survival and Regulates Intestinal Integrity
Gastroenterology, 134(4), A-35-A-36.
2008 journal article
Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitis
JOURNAL OF IMMUNOLOGY, 181(2), 1143–1152.
Contributors: R. Kajino-Sakamoto n, M. Inagaki n, E. Lippert*, S. Akira *, S. Robine *, K. Matsumoto *, C. Jobin *, n
2008 journal article
Generation of a conditional mutant allele for Tab1 in mouse
GENESIS, 46(8), 431–439.
Contributors: M. Inagaki n, Y. Komatsu *, G. Scott*, G. Yamada *, M. Ray*, n , Y. Mishina *
2008 journal article
TAB4 stimulates TAK1-TAB1 phosphorylation and binds polyubiquitin to direct signaling to NF-kappa B
JOURNAL OF BIOLOGICAL CHEMISTRY, 283(28), 19245–19254.
Contributors: T. Prickett *, n , P. Broglie n, T. Muratore-Schroeder*, J. Shabanowitz *, D. Hunt *, D. Brautigan *
2008 journal article
TAK1 regulates reactive oxygen species and cell death in keratinocytes, which is essential for skin integrity
JOURNAL OF BIOLOGICAL CHEMISTRY, 283(38), 26161–26168.
Contributors: E. Omori n, S. Morioka n, K. Matsumoto * & n
2008 journal article
TAK1-binding Protein 1, TAB1, Mediates Osmotic Stress-induced TAK1 Activation but Is Dispensable for TAK1-mediated Cytokine Signaling
JOURNAL OF BIOLOGICAL CHEMISTRY, 283(48), 33080–33086.
Contributors: M. Inagaki n, E. Omori n, J. Kim n, Y. Komatsu *, G. Scott*, M. Ray*, G. Yamada *, K. Matsumoto *, Y. Mishina *, n
2007 book
Mitochondrial Dysfunction
In Molecular and Biochemical Toxicology, Fourth Edition (pp. 319–332).
2007 journal article
Osmotic stress blocks NF-kappa B-dependent in inflammatory responses by inhibiting ubiquitination of I kappa B
FEBS LETTERS, 581(29), 5549–5554.
Contributors: W. HuangFu n, K. Matsumoto * & n
2007 journal article
TAK1 MAPK kinase kinase mediates transforming growth factor-beta signaling by targeting SnoN oncoprotein for degradation
JOURNAL OF BIOLOGICAL CHEMISTRY, 282(13), 9475–9481.
Contributors: T. Kajino *, E. Omori n, S. Ishii, K. Matsumoto * & n
2007 journal article
TAK1 is a central mediator of NOD2 signaling in epidermal cells
JOURNAL OF BIOLOGICAL CHEMISTRY, 283(1), 137–144.
Contributors: J. Kim n, E. Omori, K. Matsumoto *, G. Núñez * & n
2006 journal article
Osmotic Stress Activates the TAK1-JNK Pathway While Blocking TAK1-mediated NF-κB Activation
Journal of Biological Chemistry, 281(39), 28802–28810.
Contributors: W. HuangFu n, E. Omori n, S. Akira *, K. Matsumoto * & n
2006 journal article
Osmotic stress activates the TAK1-JNK pathway while blocking TAK1-mediated NF-kappa B activation - TAO2 regulates TAK1 pathways
Journal of Biological Chemistry, 281(39), 28802–28810.
2006 journal article
Protein phosphatase 6 down-regulates TAK1 kinase activation in the IL-1 signaling pathway
JOURNAL OF BIOLOGICAL CHEMISTRY, 281(52), 39891–39896.
Contributors: T. Kajino *, H. Ren *, S. Iemura *, T. Natsume *, B. Stefansson *, D. Brautigan *, K. Matsumoto *, n
2006 journal article
TAK1 is a component of the Epstein-Barr virus LMP1 complex and is essential for activation of JNK but not of NF-kappa B
JOURNAL OF BIOLOGICAL CHEMISTRY, 281(12), 7863–7872.
Contributors: N. Uemura*, T. Kajino *, H. Sanjo *, S. Sato *, S. Akira *, K. Matsumoto *, n
2006 journal article
TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis
JOURNAL OF BIOLOGICAL CHEMISTRY, 281(28), 19610–19617.
Contributors: E. Omori n, K. Matsumoto *, H. Sanjo *, S. Sato *, S. Akira *, R. Smart n , n
2006 journal article
TAK1 is indispensable for development of T cells and prevention of colitis by the generation of regulatory T cells
INTERNATIONAL IMMUNOLOGY, 18(10), 1405–1411.
Contributors: S. Sato *, H. Sanjo, T. Tsujimura, , M. Yamamoto, T. Kawai, O. Takeuchi, S. Akira
2006 journal article
Tab1
AfCS-Nature Molecule Pages, 3.
2006 journal article
Tak1
AfCS-Nature Molecule Pages, 1.
2005 journal article
AMP-activated protein kinase activates p38 mitogen-activated protein kinase by increasing recruitment of p38 MAPK to TAB1 in the ischemic heart
CIRCULATION RESEARCH, 97(9), 872–879.
Contributors: J. Li n, E. Miller n, n , R. Russell III & L. Young n
2005 journal article
Essential function for the kinase TAK1 in innate and adaptive immune responses
NATURE IMMUNOLOGY, 6(11), 1087–1095.
Contributors: S. Sato *, H. Sanjo *, K. Takeda *, n , M. Yamamoto *, T. Kawai *, K. Matsumoto *, O. Takeuchi *, S. Akira *
2005 journal article
TAK1-binding protein 2 facilitates ubiquitination of TRAF6 and assembly of TRAF6 with IKK in the IL-1 signaling pathway
GENES TO CELLS, 10(5), 447–454.
Contributors: S. Kishida n, H. Sanjo *, S. Akira *, K. Matsumoto * & n
2005 journal article
Transforming growth factor beta-activated kinase 1 is a key mediator of ovine follicle-stimulating hormone beta-subunit expression
ENDOCRINOLOGY, 146(11), 4814–4824.
2004 journal article
Activation mechanism of c-Jun amino-terminal kinase in the course of neural differentiation of P19 embryonic carcinoma cells
JOURNAL OF BIOLOGICAL CHEMISTRY, 279(35), 36616–36620.
Contributors: S. Akiyama *, T. Yonezawa *, T. Kudo *, M. Li*, H. Wang*, M. Ito *, K. Yoshioka *, n
2004 journal article
Involvement of ASK1 in Ca 2+ ‐induced p38 MAP kinase activation
EMBO Reports, 5(2), 161–166.
Contributors: K. Takeda *, A. Matsuzawa *, H. Nishitoh *, K. Tobiume *, S. Kishida*, * , K. Matsumoto *, H. Ichijo *
2004 journal article
Wnt-1 signal induces, phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK
Genes and Development, 18(7), 816–829.
Contributors: C. Kanei-Ishii*, * , J. Tanikawa *, T. Nomura*, T. Ishitani *, S. Kishida*, K. Kokura *, T. Kurahashi *
2003 journal article
A dominant negative TAK1 inhibits cellular fibrotic responses induced by TGF-beta
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 307(2), 332–337.
2003 journal article
A resorcylic acid lactone, 5Z-7-oxozeaenol, prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase
JOURNAL OF BIOLOGICAL CHEMISTRY, 278(20), 18485–18490.
Contributors: , T. Kajino *, K. Ono, T. Ohtomo, M. Matsumoto, M. Shiina, M. Mihara, M. Tsuchiya, K. Matsumoto * n
2003 journal article
Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/β-catenin signaling
Molecular and Cellular Biology, 23(4), 1379–1389.
Contributors: T. Ishitani *, * & K. Matsumoto *
2003 journal article
Regulation of the interleukin-1-induced signaling pathways by a novel member of the protein phosphatase 2C family (PP2C epsilon)
JOURNAL OF BIOLOGICAL CHEMISTRY, 278(14), 12013–12021.
Contributors: M. Li*, K. Katsura*, H. Nomiyama *, K. Komaki*, n , K. Matsumoto *, T. Kobayashi*, S. Tamura*
2003 journal article
Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling
EMBO Journal, 22(23), 6277–6288.
Contributors: T. Ishitani *, G. Takaesu *, * , H. Shibuya *, R. Gaynor* & K. Matsumoto *
2003 journal article
TAB2 is essential for prevention of apoptosis in fetal liver but not for interleukin-1 signaling
Molecular and Cellular Biology, 23(4), 1231–1238.
Contributors: H. Sanjo *, K. Takeda *, T. Tsujimura *, * , K. Matsumoto * & S. Akira *
2003 journal article
TAK1 is critical for I kappa B kinase-mediated activation of the NF-kappa B pathway
JOURNAL OF MOLECULAR BIOLOGY, 326(1), 105–115.
Contributors: G. Takaesu *, R. Surabhi*, K. Park*, n , K. Matsumoto * & R. Gaynor*
2002 journal article
Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol
Molecular and Cellular Biology, 22(20), 7158–7167.
Contributors: Z. Jiang *, * , Y. Qian *, K. Matsumoto * & X. Li *
2002 journal article
Receptor activator of NF-κB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6
Molecular and Cellular Biology, 22(4), 992–1000.
Contributors: J. Mizukami, G. Takaesu *, H. Akatsuka*, H. Sakurai *, * , K. Matsumoto *, N. Sakurai *
2002 journal article
SEK-1 MAPKK mediates Ca2+ signaling to determine neuronal asymmetric development in Caenorhabditis elegans
EMBO Reports, 3(1), 56–62.
Contributors: M. Tanaka-Hino*, A. Sagasti *, N. Hisamoto *, M. Kawasaki *, S. Nakano *, * , C. Bargmann *, K. Matsumoto *
2002 journal article
Targeted disruption of the Tab1 gene causes embryonic lethality and defects in cardiovascular and lung morphogenesis
MECHANISMS OF DEVELOPMENT, 119(2), 239–249.
Contributors: Y. Komatsu *, H. Shibuya *, N. Takeda *, n , T. Yasui*, K. Miyado *, T. Sekimoto*, N. Ueno *, K. Matsumoto *, G. Yamada *
2002 journal article
The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca<sup>2+</sup> pathway to antagonize Wnt/β-catenin signaling
Molecular and Cellular Biology, 23(1), 131–139.
Contributors: T. Ishitani *, S. Kishida*, J. Hyodo-Miura*, N. Ueno *, J. Yasuda *, M. Waterman *, H. Shibuya *, R. Moon *, * , K. Matsumoto *
2001 journal article
A Drosophila MAPKKK, D-MEKK1, mediates stress responses through activation of p38 MAPK
EMBO Journal, 20(19), 5421–5430.
Contributors: H. Inoue *, M. Tateno*, K. Fujimura-Kamada, G. Takaesu *, T. Adachi-Yamada *, * , K. Irie *, Y. Nishida*, K. Matsumoto *
2001 journal article
An Evolutionarily Conserved Motif in the TAB1 C-terminal Region is Necessary for Interaction with and Activation of TAK1 MAPKKK
Journal of Biological Chemistry, 276(26), 24396–24400.
Contributors: K. Ono, T. Ohtomo, S. Sato, Y. Sugamata, M. Suzuki*, N. Hisamoto *, * , M. Tsuchiya, K. Matsumoto *
2001 journal article
IRAK-mediated Translocation of TRAF6 and TAB2 in the Interleukin-1-induced Activation of NFκB
Journal of Biological Chemistry, 276(45), 41661–41667.
Contributors: Y. Qian *, M. Commane*, * , K. Matsumoto * & X. Li *
2001 journal article
Interleukin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathway
Molecular and Cellular Biology, 21(7), 2475–2484.
Contributors: G. Takaesu *, * , S. Kishida*, X. Li, G. Stark * & K. Matsumoto *
2001 journal article
Regulation of the TAK1 Signaling Pathway by Protein Phosphatase 2C
Journal of Biological Chemistry, 276(8), 5753–5759.
Contributors: M. Hanada*, * , K. Komaki*, M. Ohnishi, K. Katsura, R. Kanamaru*, K. Matsumoto *, S. Tamura
2001 journal article
The MAPK Kinase Kinase TAK1 Plays a Central Role in Coupling the Interleukin-1 Receptor to Both Transcriptional and RNA-targeted Mechanisms of Gene Regulation
Journal of Biological Chemistry, 276(5), 3508–3516.
Contributors: H. Holtmann*, J. Enninga *, S. Kälble*, A. Thiefes*, A. Dörrie*, M. Broemer *, R. Winzen*, A. Wilhelm*
2000 journal article
ASK1 inhibits interleukin-1-induced NF-κB activity through disruption of TRAF6-TAK1 interaction
Journal of Biological Chemistry, 275(42), 32747–32752. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034693222&partnerID=MN8TOARS
2000 journal article
Molecular cloning of MINK, a novel member of mammalian GCK family kinases, which is up-regulated during postnatal mouse cerebral development
FEBS Letters, 469(1), 19–23.
Contributors: I. Dan, N. Watanabe*, T. Kobayashi, K. Yamashita-Suzuki, Y. Fukagaya, E. Kajikawa, W. Kimura*, T. Nakashima *
2000 journal article
TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway
Molecular Cell, 5(4), 649–658. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033634977&partnerID=MN8TOARS
2000 journal article
TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop
Journal of Biological Chemistry, 275(10), 7359–7364.
Contributors: K. Kishimoto*, K. Matsumoto * & *
1999 journal article
A Caenorhabditis elegans JNK signal transduction pathway regulates coordinated movement via type-D GABAergic motor neurons
EMBO Journal, 18(13), 3604–3615.
Contributors: M. Kawasaki *, N. Hisamoto *, Y. Lino, M. Yamamoto *, * & K. Matsumoto *
1999 journal article
Involvement of the p38 mitogen-activated protein kinase pathway in transforming growth factor-β-induced gene expression
Journal of Biological Chemistry, 274(38), 27161–27167.
Contributors: H. Hanafusa *, * , N. Masuyama*, M. Nishita *, J. Fujisawa *, H. Shibuya *, K. Matsumoto *, E. Nishida *
1999 journal article
Map kinase and Wnt pathways converge to downregulate an HMG-domain repressor in Caenorhabditis elegans
Nature, 399(6738), 793–797.
Contributors: M. Meneghini *, T. Ishitani *, J. Carter*, N. Hisamoto *, * , C. Thorpe *, D. Hamill *, K. Matsumoto *, B. Bowerman *
1999 journal article
The TAK1-NLK-MAPK-related pathway antagonizes signalling between β- catenin and transcription factor TCF
Nature, 399(6738), 798–802.
Contributors: T. Ishitani *, * , S. Nagai*, M. Nishita *, M. Meneghini *, N. Barker *, M. Waterman *, B. Bowerman *
1999 journal article
The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway
Nature, 398(6724), 252–256.
Contributors: , K. Kishimoto*, A. Hiyama*, J. Inoue *, Z. Cao & K. Matsumoto * *
1999 journal article
XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway
EMBO Journal, 18(1), 179–187.
Contributors: K. Yamaguchi *, S. Nagai, , M. Nishita, K. Tamai, K. Irie, N. Ueno, E. Nishida, H. Shibuya, K. Matsumoto
1997 journal article
Functional analyses of mammalian protein kinase C isozymes in budding yeast and mammalian fibroblasts
Genes to Cells, 2(10), 601–614. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031240976&partnerID=MN8TOARS
1997 journal article
TGF-beta signaling
Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme, 42(10 Suppl), 1517–1524. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031183774&partnerID=MN8TOARS
1996 journal article
G<inf>1</inf> phase-specific suppression of the Cdk2 activity by ginsenoside Rh<inf>2</inf> in cultured murine cells
Life Sciences, 60(2).
Contributors: T. Ota*, M. Maeda*, S. Odashima*, * & M. Tatsuka *
1993 journal article
Augmentation by IL-1α of tumor necrosis factor-α cytotoxicity in cells transfected with adenovirus E1A
Journal of Immunology, 150(5), 1897–1907. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027223371&partnerID=MN8TOARS
1993 journal article
Selective loss of CDC2 and CDK2 induction by tumor necrosis factor-α in senescent human diploid fibroblasts
Experimental Cell Research, 209(2), 175–182. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027146392&partnerID=MN8TOARS
1993 journal article
Tumor necrosis factor-induced c-myc expression in the absence of mitogenesis is associated with inhibition of adipocyte differentiation
Proceedings of the National Academy of Sciences of the United States of America, 90(20), 9611–9615. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027491022&partnerID=MN8TOARS
1992 journal article
Cyclin-dependent kinase 2 (cdk2) in the murine cdc2 kinase TS mutant
Somatic Cell and Molecular Genetics, 18(5), 403–408.
Contributors: H. Yasuda*, T. Nakata *, M. Kamijo*, R. Honda*, M. Nakamura*, * , M. Yamashita *, Y. Nagahama*, Y. Ohba*
1992 journal article
IL-2 and EGF receptors stimulate the hematopoietic cell cycle via different signaling pathways: Demonstration of a novel role for c-myc
Cell, 70(1), 57–67.
Contributors: H. Shibuya *, M. Yoneyama *, * , K. Matsumoto * & T. Taniguchi *
1992 journal article
New human gene encoding a positive modulator of HIV Tat-mediated transactivation
Nature, 357(6380), 700–702. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026689020&partnerID=MN8TOARS
1991 journal article
Cloning of a human cDNA encoding a CDC2-related kinase by complementation of a budding yeast cdc28 mutation
Proceedings of the National Academy of Sciences of the United States of America, 88(20), 9006–9010. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025946804&partnerID=MN8TOARS
1990 journal article
A temperature-sensitive cell-cycle mutant of mammalian cells, tsJT16, is defective in a function operating soon after growth stimulation
Cell Structure and Function, 15(1), 39–45. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025276307&partnerID=MN8TOARS
1990 journal article
Nonlethal G<inf>0</inf>-ts mutant tsJT60 becomes lethal at the nonpermissive temperature after transformation: A hint for new cancer chemotherapeutics
Cell Structure and Function, 15(6), 385–391.
Contributors: Y. Tai*, * , K. Furuoku*, N. Ogawa *, S. Ishibashi*, K. Shiroki*, K. Segawa*, N. Tsuchida, M. Shibuya*, T. Ide*
1988 journal article
A cell cycle G<inf>0</inf>-ts mutant, tsJT60, becomes lethal at the nonpermissive temperature after transformation with adenovirus 12 E1B 19K mutant
Experimental Cell Research, 179(1), 50–57.
1987 journal article
Bypass of the ts Block of tsJT60, a G<inf>0</inf>-Specific ts Mutant from Rat Fibroblasts, by Fetal Bovine Serum and Epidermal Growth Factor
Cell Structure and Function, 12(5), 421–432.
Contributors: , Y. Nakahara *, C. Ito*, T. Akiyama *, S. Ishibashi* & T. Ide *
1987 journal article
Colchicine activates cell cycle-dependent genes in growth-arrested rat 3Y1 cells
Experimental Cell Research, 173(1), 294–298.
Contributors: M. Miura*, * , Y. Tsuji *, S. Ishibashi* & T. Ide*
1987 journal article
Entrance of SV40-transformed Cells into g0 Phase as Revealed by a Study Using the g0-specific ts mutant tsjt60
Cancer Research, 47(22), 6028–6032. http://www.scopus.com/inward/record.url?eid=2-s2.0-0023589313&partnerID=MN8TOARS
1987 journal article
Epidermal growth factor has a unique effect in combination with fetal bovine serum to bypass the ts-block of G<inf>o</inf>-specific ts mutant tsJT60
Experimental Cell Research, 171(1), 86–93.
Contributors: , Y. Nakahara *, C. Ito*, T. Akiyama *, S. Ishibashi* & T. Ide* *
1987 journal article
Induction of cellular DNA synthesis in G<inf>0</inf>-specific ts mutant, tsJT60, following Infection with SV40 and adenoviruses
Experimental Cell Research, 171(2), 509–512.
1987 journal article
tsJT60, a cell cycle G0-ts mutant, becomes lethal at non-permissive temperature by transformation with adenovirus 5 when the expression of E1B gene is lacking
Experimental Cell Research, 170(2), 491–498.
Contributors: Y. Goto*, * , K. Tanonaka *, S. Ishibashi*, K. Shiroki* & T. Ide*
1986 journal article
Defect in prereplicative phase of G0-specific ts mutant, tsJT60
Experimental Cell Research, 165(1), 191–198.
1986 journal article
Expression of Growth-Regulated Genes in tsJT60 Cells, a Temperature-Sensitive Mutant of the Cell Cycle
Biochemistry, 25(22), 7041–7046.
1986 journal article
Failure in S6 protein phosphorylation by serum stimulatio of senescent human diploid fibroblasts, TIG-1
Mechanisms of Ageing and Development, 37(1), 27–40.
1986 journal article
Isolation of ts mutant cells which arrest in G1/G0 phase at the non-permissive temperature in the presence of appropriate growth factors from a Fischer rat cell line, 3Y1
Experimental Cell Research, 165(2), 337–344.
Contributors: K. Tanonaka *, * , S. Ishibashi* & T. Ide*
1984 journal article
Isolation of a G0-specific ts mutant from a Fischer rat cell line, 3Y1
Experimental Cell Research, 150(1), 60–67.
Contributors: T. Ide*, J. Ninomiya* & S. Ishibashi*
1984 journal article
Isolation of a G0-specific ts mutant from a Fischer rat cell line, 3Y1.
Exp. Cell Res.
Updated: August 30th, 2024 11:58
2013 - present
2008 - 2013
2002 - 2008
Funding history based on the linked ORCID record. Updated: November 9th, 2021 11:45
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