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Works (20)
Updated: April 5th, 2024 03:40
2022 journal article
Differences in the Propensity of Different Antimicrobial Resistance Determinants to Be Disseminated via Transformation in Campylobacter jejuni and Campylobacter coli
MICROORGANISMS, 10(6).
author keywords: antimicrobial resistance; AMR; Campylobacter; transformation
TL;DR:
Findings from this experimental model provide insights into factors that may impact transformation-mediated transfer of AMR leading to AMR dissemination in the agricultural ecosystem.
(via Semantic Scholar)
open access via www.mdpi.com (publisher PDF)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: July 5, 2022
2018 journal article
Interaction of Copper Toxicity and Oxidative Stress in Campylobacter jejuni
Journal of Bacteriology, 200(21).
Ed(s): V. DiRita
author keywords: Campylobacter; copper
MeSH headings : Animal Feed / analysis; Animal Feed / toxicity; Animals; Bacterial Proteins / genetics; Campylobacter jejuni / drug effects; Campylobacter jejuni / genetics; Campylobacter jejuni / metabolism; Chickens; Copper / toxicity; Copper Sulfate / toxicity; Mutation; Oxidation-Reduction; Oxidative Stress; Oxidoreductases / genetics
TL;DR:
The results indicate that copper toxicity in C. jejuni is due to a failure to effectively sequester cytoplasmic copper, resulting in an increase in copper-mediated oxidative damage.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: April 4, 2022
2016 journal article
Identification of a Campylobacter coli methyltransferase targeting adenines at GATC sites
FEMS Microbiology Letters, 364(7).
MeSH headings : Adenine / metabolism; Animals; Campylobacter coli / enzymology; Campylobacter coli / genetics; Cattle; DNA Methylation; Genome, Bacterial; Humans; Methyltransferases / genetics; Methyltransferases / isolation & purification; Methyltransferases / metabolism; Nucleotide Motifs; Open Reading Frames; Sequence Analysis / methods
TL;DR:
To determine whether ORF0059 mediated MboI resistance and hence encoded a putative N6‐adenine DNA methyltransferase, the gene was cloned immediately upstream of a chloramphenicol resistance cassette (cat) and a PCR fragment harboring ORF 0059‐cat was transformed into C. coli 11601, suggesting a direct role of this gene in methylation of adenines at GATC sites.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Novel plasmid conferring kanamycin and tetracycline resistance in the turkey-derived Campylobacter jejuni strain 11601MD
PLASMID, 86, 32–37.
author keywords: Campylobacter; C. jejuni; Plasmid; Antibiotic resistance; tet(O); Tetracycline resistance; Kanamycin resistance; aphA-3
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Bacterial Proteins / genetics; Base Composition; Base Sequence; Campylobacter jejuni / drug effects; Campylobacter jejuni / genetics; Campylobacter jejuni / isolation & purification; Carrier Proteins / genetics; Conjugation, Genetic / genetics; DNA, Bacterial / genetics; Jejunum / microbiology; Kanamycin / pharmacology; Kanamycin Kinase / genetics; Microbial Sensitivity Tests; North Carolina; Plasmids / genetics; Poultry Diseases / microbiology; Sequence Analysis, DNA; Tetracycline / pharmacology; Tetracycline Resistance / genetics; Turkeys / microbiology
TL;DR:
A novel plasmid harboring tet(O) was identified in C. jejuni strain 11601MD, which was isolated from the jejunum of a turkey produced conventionally in North Carolina, and will contribute to a better understanding of the distribution of potentially self-mobilizing plasmids harboring antibiotic resistance determinants in Campylobacter spp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Aerobic Hydrogen Production via Nitrogenase in Azotobacter vinelandii CA6
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 81(13), 4507–4516.
Contributors: J. Noar n, T. Loveless*, J. Navarro-Herrero, n & J. Bruno-Bárcena n
MeSH headings : Aerobiosis; Azotobacter vinelandii / enzymology; Azotobacter vinelandii / genetics; Azotobacter vinelandii / metabolism; Genome, Bacterial; Hydrogen / metabolism; Iron / metabolism; Metabolic Networks and Pathways / genetics; Nitrogenase / metabolism; Tungsten Compounds / metabolism
TL;DR:
A large deletion in CA6's genome is revealed, encompassing genes related to molybdate and iron transport and hydrogen reoxidation, which may hold promise for developing a novel strategy for production of hydrogen as an energy compound.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2014 journal article
The impairment of methylmenaquinol:fumarate reductase affects hydrogen peroxide susceptibility and accumulation in Campylobacter jejuni
MICROBIOLOGYOPEN, 3(2), 168–181.
author keywords: C. jejuni; catalase; hydrogen peroxide resistance; iron; macrophage; methylmenaquinol:fumarate reductase; Mfr
MeSH headings : Animals; Campylobacter jejuni / drug effects; Campylobacter jejuni / enzymology; Campylobacter jejuni / genetics; Cell Line; Gene Deletion; Hydrogen Peroxide / toxicity; Iron / metabolism; Macrophages / cytology; Macrophages / microbiology; Mice; Microbial Sensitivity Tests; Microbial Viability / drug effects; Microscopy, Electron, Scanning; Succinate Dehydrogenase / genetics; Succinate Dehydrogenase / metabolism
TL;DR:
A role for Mfr is suggested in maintaining iron homeostasis in H2O2 stressed C. jejuni, probably via affecting the concentrations of intracellular iron.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2012 article
Barriers to Horizontal Gene Transfer in Campylobacter jejuni
ADVANCES IN APPLIED MICROBIOLOGY, VOL 79, Vol. 79, pp. 19–42.
MeSH headings : Campylobacter; Campylobacter jejuni; Escherichia coli / genetics; Gene Transfer, Horizontal; Plasmids
TL;DR:
The modes of genetic transfer in C. jejuni are reviewed and the current state of research into the mechanism of each is reviewed and two systems (CRISPR-Cas and restriction modification) are reviewed that are common to many strains of C.Jejuni and are at least partly responsible for these barriers.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Chromosomal tet(O)-Harboring Regions in Campylobacter coli Isolates from Turkeys and Swine
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 78(23), 8488–8491.
MeSH headings : Animals; Campylobacter Infections / microbiology; Campylobacter Infections / veterinary; Campylobacter coli / drug effects; Campylobacter coli / genetics; Campylobacter coli / isolation & purification; Carrier Proteins / genetics; Chromosomes, Bacterial; DNA Transposable Elements; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Genes, Bacterial; Molecular Sequence Data; Mutagenesis, Insertional; Poultry Diseases / microbiology; Sequence Analysis, DNA; Swine; Swine Diseases / microbiology; Tetracycline Resistance; Turkeys
TL;DR:
In turkey-derived Campylobacter coli isolates of a unique lineage (cluster II), the tetracycline resistance determinant tet(O) was chromosomal and was part of a gene cassette (transposon) interrupting a Campyloblacter jejuni-associated putative citrate transporter gene.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Production of polyhydroxybutyrate (PHB) by Alcaligenes latus using sugarbeet juice
INDUSTRIAL CROPS AND PRODUCTS, 43, 802–811.
author keywords: Biodegradable plastics; Polyhydroxyalkanoate (PHA); Sucrose; Two-stage batch fermentation
UN Sustainable Development Goal Categories
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 journal article
Respiratory proteins contribute differentially to Campylobacter jejuni's survival and in vitro interaction with hosts' intestinal cells
BMC MICROBIOLOGY, 12.
author keywords: Campylobacter jejuni; Respiratory proteins; Survival; Adaptation; Motility; Oxidative stress; Biofilm; Oxygen; Temperature; INT-407; Chicken intestinal epithelial cells
MeSH headings : Animals; Bacterial Adhesion; Bacterial Proteins / metabolism; Biofilms / growth & development; Campylobacter jejuni / drug effects; Campylobacter jejuni / pathogenicity; Campylobacter jejuni / physiology; Campylobacter jejuni / radiation effects; Chickens; Epithelial Cells / microbiology; Gene Deletion; Humans; Hydrogen Peroxide / toxicity; Locomotion; Microbial Viability; Microscopy, Electron, Scanning; Oxidoreductases / genetics; Oxidoreductases / metabolism; Temperature; Virulence Factors / metabolism
TL;DR:
The objectives were to characterize the contributions of selected RPs to C. jejuni’s motility, H2O2 resistance, biofilm formation, and in vitro interactions with hosts’ intestinal cells, and to conclude that the RPs contribute to the pathogen's remarkable potential for adaptation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Upstream process optimization of polyhydroxybutyrate (PHB) by Alcaligenes latus using two-stage batch and fed-batch fermentation strategies
Bioprocess and Biosystems Engineering, 35(9), 1591–1602.
author keywords: Biodegradable plastics; Polyhydroxyalkanoate (PHA); Ralstonia eutropha; Sucrose fermentation; Nitrogen limitation
MeSH headings : Alcaligenes / growth & development; Culture Media / pharmacology; Polyesters / metabolism; Sucrose / pharmacology; Sweetening Agents / pharmacology
TL;DR:
Inducing nitrogen limitation at 16 h and ending second stage at 26 h gave optimal performance for PHB production, resulting in a PHB content of 46.7 ± 12.2 % (g PHB per g dry cell weight) at the end of fermentation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
12. Responsible Consumption and Production
(Web of Science)
Source: Crossref
Added: August 28, 2020
2009 journal article
Molybdenum and tungsten in Campylobacter jejuni: their physiological role and identification of separate transporters regulated by a single ModE-like protein
MOLECULAR MICROBIOLOGY, 74(3), 758–771.
MeSH headings : ATP-Binding Cassette Transporters / genetics; ATP-Binding Cassette Transporters / metabolism; Amino Acid Sequence; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Campylobacter jejuni / genetics; Campylobacter jejuni / metabolism; Electron Transport / genetics; Escherichia coli / genetics; Escherichia coli / metabolism; Formate Dehydrogenases / genetics; Formate Dehydrogenases / metabolism; Humans; Membrane Transport Proteins / genetics; Membrane Transport Proteins / metabolism; Molecular Sequence Data; Molybdenum / chemistry; Molybdenum / metabolism; Nitrate Reductase / genetics; Nitrate Reductase / metabolism; Nitrate Reductase (NAD(P)H) / metabolism; Nitrate Reductases / chemistry; Nitrate Reductases / genetics; Nitrate Reductases / metabolism; Phylogeny; Protein Engineering; Pterins / metabolism; Sequence Alignment; Sequence Homology, Amino Acid; Transcription Factors / metabolism; Tungsten / chemistry; Tungsten / metabolism
TL;DR:
Results indicate that mod is primarily a molybdenum transporter that can also transport tungsten, while tup is a tungsen‐specific transporter.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
The Dual-Functioning Fumarate Reductase Is the Sole Succinate: Quinone Reductase in Campylobacter jejuni and Is Required for Full Host Colonization
JOURNAL OF BACTERIOLOGY, 191(16), 5293–5300.
MeSH headings : Animals; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Bacterial Proteins / physiology; Campylobacter jejuni / enzymology; Campylobacter jejuni / genetics; Campylobacter jejuni / growth & development; Campylobacter jejuni / metabolism; Chickens; Citric Acid Cycle / genetics; Citric Acid Cycle / physiology; Fumarates / metabolism; Models, Genetic; Oxygen / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Succinate Dehydrogenase / genetics; Succinate Dehydrogenase / metabolism; Succinate Dehydrogenase / physiology; Succinic Acid / metabolism
TL;DR:
Campylobacter jejuni encodes all the enzymes necessary for a complete oxidative tricarboxylic acid (TCA) cycle and the in vivo importance of succinate oxidation was confirmed, as the frdA::cat(+) strain colonized chickens at significantly lower levels than the wild type, while the sdhA:: cat(+) strain colonize chickens at wild-type levels.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
The role of respiratory donor enzymes in Campylobacter jejuni host colonization and physiology
MICROBIAL PATHOGENESIS, 47(1), 8–15.
author keywords: Campylobacter; Colonization; Respiration; Hydrogen; Formate
MeSH headings : Animals; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Campylobacter Infections / microbiology; Campylobacter jejuni / enzymology; Campylobacter jejuni / pathogenicity; Chickens; Formate Dehydrogenases / genetics; Formate Dehydrogenases / metabolism; Gene Knockout Techniques; Humans; Hydrogenase / genetics; Hydrogenase / metabolism; Ketone Oxidoreductases / genetics; Ketone Oxidoreductases / metabolism; Mutagenesis, Insertional; Virulence; Virulence Factors / genetics; Virulence Factors / metabolism
TL;DR:
The importance of hydrogenase, formate dehydrogenase and OOR as well as the complex I of C. jejuni are elucidated by chicken colonization assays, where the double mutant Hyd::Fdh, OorB::CM and nuo mutants are severely impaired in host colonization.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2008 journal article
Role of Campylobacter jejuni respiratory oxidases and reductases in host colonization
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 74(5), 1367–1375.
MeSH headings : Animals; Campylobacter jejuni / enzymology; Campylobacter jejuni / growth & development; Cecum / microbiology; Chickens / microbiology; Colony Count, Microbial; DNA Primers / genetics; Gene Components; Mass Spectrometry; Mutagenesis; Nitrates / metabolism; Oxidoreductases / genetics; Oxidoreductases / metabolism; Oxygen / metabolism; Species Specificity
TL;DR:
While there appears to be a role for anaerobic respiration in host colonization, oxygen is the most important respiratory acceptor for C. jejuni in the chicken cecum.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2007 journal article
The Campylobacter jejuni NADH : Ubiquinone oxidoreductase (complex I) utilizes flavodoxin rather than NADH
JOURNAL OF BACTERIOLOGY, 190(3), 915–925.
MeSH headings : Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Campylobacter jejuni / enzymology; Campylobacter jejuni / genetics; Campylobacter jejuni / metabolism; Culture Media; Electron Transport Complex I / genetics; Electron Transport Complex I / metabolism; Flavodoxin / genetics; Flavodoxin / metabolism; Gene Deletion; Gene Expression Regulation, Bacterial; Genes, Essential; Humans; NAD / metabolism; Oxidation-Reduction; Oxygen Consumption
TL;DR:
A series of mutants was generated in which each of the 12 nuo genes (homologues to known complex I subunits) was disrupted or deleted and a model is presented in which CJ1574 mediates electron flow into the respiratory transport chain from reduced flavodoxin and through complex I.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2004 journal article
Helicobacter pylori FlgR is an enhancer-independent activator of sigma(54)-RNA polymerase holoenzyme
Journal of Bacteriology, 186(14), 4535–4542.
Source: NC State University Libraries
Added: August 6, 2018
2004 journal article
Role of a Bacterial Organic Hydroperoxide Detoxification System in Preventing Catalase Inactivation
Journal of Biological Chemistry, 279(50), 51908–51914.
MeSH headings : Antioxidants / metabolism; Base Sequence; Catalase / antagonists & inhibitors; Catalase / genetics; Catalase / metabolism; DNA, Bacterial / genetics; Genes, Bacterial; Helicobacter pylori / genetics; Helicobacter pylori / metabolism; Helicobacter pylori / pathogenicity; Heme / metabolism; Humans; Hydrogen Peroxide / metabolism; In Vitro Techniques; Lipid Peroxides / metabolism; Mutation; Oxidative Stress; Peroxidases / genetics; Peroxidases / metabolism; Peroxiredoxins
TL;DR:
The findings reveal a novel role of the organic hydroperoxide detoxification system in preventing catalase inactivation and compare the level of lipid peroxidation found in ahpC mutant cells with that found in wild type cells.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
1996 journal article
Polymerase chain reaction evidence of ehrlichia chaffeensis, an agent of human ehrlichiosis, in dogs from Southeast Virginia
American Journal of Veterinary Research, 57, 1175–1179.
Source: NC State University Libraries
Added: August 6, 2018
journal article
Upstream process optimization of polyhydroxybutyrate (PHB) by Alcaligenes latus using two-stage batch and fed-batch fermentation strategies
Wang, B. Q., Sharma-Shivappa, R. R., Olson, J. W., & Khan, S. A. Bioprocess and Biosystems Engineering, 35(9), 1591–1602.
Source: NC State University Libraries
Added: August 6, 2018
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