Jun Yan

Works (3)

Updated: April 29th, 2024 09:15

2007 journal article

Design and synthesis of boronic-acid-labeled thymidine triphosphate for incorporation into DNA

Nucleic Acids Research, 35(4), 1222–1229.

By: N. Lin n, J. Yan n, Z. Huang  n, C. Altier n, M. Li  n, N. Carrasco n, M. Suyemoto n, L. Johnston n ...

MeSH headings : Aptamers, Nucleotide / chemistry; Boron Compounds / chemical synthesis; Boron Compounds / chemistry; Boron Compounds / metabolism; DNA / biosynthesis; DNA / chemistry; DNA Primers; DNA-Directed DNA Polymerase / metabolism; Polymerase Chain Reaction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Templates, Genetic; Thymine Nucleotides / chemical synthesis; Thymine Nucleotides / chemistry; Thymine Nucleotides / metabolism
TL;DR: It is demonstrated that DNA polymerase can effectively recognize the B-TTP as the template for DNA polymerization, that allows PCR amplification of boronic acid-labeled DNA. (via Semantic Scholar)
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Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

A novel type of fluorescent boronic acid that shows large fluorescence intensity changes upon binding with a carbohydrate in aqueous solution at physiological pH

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 13(6), 1019–1022.

By: W. Yang n, J. Yan n, G. Springsteen n, S. Deeter n & B. Wang n

MeSH headings : Boronic Acids / chemical synthesis; Boronic Acids / chemistry; Carbohydrates / chemistry; Fluorescent Dyes / chemical synthesis; Fluorescent Dyes / chemistry; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Quinolines / chemical synthesis; Quinolines / chemistry; Solutions
TL;DR: 8-quinolineboronic acid is reported as a novel type of fluorescent probe for carbohydrates that responds to the binding of a carbohydrate with over 40-fold increases in fluorescence intensity and shows optimal fluorescence change at physiological pH in aqueous solution. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2003 journal article

The first fluorescent sensor for D-glucarate based on the cooperative action of boronic acid and guanidinium groups

CHEMICAL COMMUNICATIONS, (6), 792–793.

By: W. Yang n, J. Yan n, H. Fang n & B. Wang n

MeSH headings : Binding Sites; Biosensing Techniques / methods; Boronic Acids / chemistry; Fluorescent Dyes / chemistry; Glucaric Acid / isolation & purification; Glucaric Acid / metabolism; Guanidine / chemistry; Models, Molecular; Spectrometry, Fluorescence
TL;DR: A new fluorescent sensor with a recognition unit consisting of a boronic acid moiety and a guanidinium unit shows selective binding of D-glucarate in aqueous solution. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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