Katherine A. McCaffrey

Works (5)

Updated: July 5th, 2023 15:46

2013 article

Sex specific impact of perinatal bisphenol A (BPA) exposure over a range of orally administered doses on rat hypothalamic sexual differentiation

McCaffrey, K. A., Jones, B., Mabrey, N., Weiss, B., Swan, S. H., & Patisaul, H. B. (2013, March 13). NeuroToxicology, Vol. 36, pp. 55–62.

By: K. McCaffrey n, B. Jones *, N. Mabrey n, B. Weiss *, S. Swan * & H. Patisaul n 

author keywords: Endocrine disruption; Estrogen; Hypothalamus; Sexually dimorphic; Dopamine
MeSH headings : Administration, Oral; Air Pollutants, Occupational / toxicity; Analysis of Variance; Animals; Benzhydryl Compounds / administration & dosage; Benzhydryl Compounds / toxicity; Calbindins / metabolism; Cell Count; Dose-Response Relationship, Drug; Female; Hypothalamus / drug effects; Hypothalamus / metabolism; Male; Phenols / administration & dosage; Phenols / toxicity; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Rats; Rats, Long-Evans; Sex Differentiation / physiology; Tyrosine 3-Monooxygenase / metabolism
topics (OpenAlex): Effects and risks of endocrine disrupting chemicals
TL;DR: It is demonstrated that early life oral exposure to BPA at levels well below the current No Observed Adverse Effect Level (NOAEL) of 50mg/kg/day can alter sex specific hypothalamic morphology in the rat. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2012 journal article

Accumulation and Endocrine Disrupting Effects of the Flame Retardant Mixture Firemaster®550 in Rats: An Exploratory Assessment

Journal of Biochemical and Molecular Toxicology, 27(2), 124–136.

By: H. Patisaul n , S. Roberts*, N. Mabrey n, K. McCaffrey n, R. Gear*, J. Braun *, S. Belcher* , H. Stapleton *

Contributors: H. Patisaul n , S. Roberts*, N. Mabrey n, K. Mccaffrey n, R. Gear*, J. Braun *, S. Belcher* , H. Stapleton *

author keywords: Anxiety; Cardiac Hypertrophy; Endocrine Disruptor; Flame Retardants; Metabolic Syndrome; Metabolism; Obesity; Obesogen; Polybrominated Diphenyl Ethers; Rodents
MeSH headings : Animals; Cardiomegaly / blood; Cardiomegaly / chemically induced; Cardiomegaly / pathology; Endocrine System / metabolism; Endocrine System / pathology; Endocrine System / physiology; Female; Flame Retardants / adverse effects; Male; Maternal Exposure / adverse effects; Obesity / blood; Obesity / chemically induced; Obesity / pathology; Pregnancy; Prenatal Exposure Delayed Effects / blood; Prenatal Exposure Delayed Effects / pathology; Rats; Rats, Wistar; Thyroxine / blood
topics (OpenAlex): Toxic Organic Pollutants Impact; Effects and risks of endocrine disrupting chemicals; Carcinogens and Genotoxicity Assessment
TL;DR: Results are the first to implicate FM 550 as an endocrine disruptor and an obesogen at environmentally relevant levels and induced phenotypic hallmarks associated with metabolic syndrome in the offspring. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2012 journal article

Ants of North Carolina: An updated list (Hymenoptera: Formicidae)

Zootaxa, (3552), 1–36.

By: B. Guenard, K. Mccaffrey, A. Lucky & R. Dunn 

Source: NC State University Libraries
Added: August 6, 2018

2012 article

Disrupted Organization of RFamide Pathways in the Hypothalamus Is Associated with Advanced Puberty in Female Rats Neonatally Exposed to Bisphenol A1

Losa-Ward, S. M., Todd, K. L., McCaffrey, K. A., Tsutsui, K., & Patisaul, H. B. (2012, May 10). Biology of Reproduction, Vol. 87.

By: S. Losa-Ward n, K. Todd n, K. McCaffrey n, K. Tsutsui * & H. Patisaul n 

author keywords: endocrine disruptor; kisspeptin; puberty; RFRP
MeSH headings : Animals; Benzhydryl Compounds; Body Weight / drug effects; Estrogens, Non-Steroidal / toxicity; Female; Gonadotropin-Releasing Hormone / metabolism; Hypothalamus / drug effects; Kisspeptins / metabolism; Male; Neuropeptides / metabolism; Phenols / toxicity; Puberty, Precocious / blood; Puberty, Precocious / chemically induced; Rats; Rats, Transgenic; Rats, Wistar; Vagina / drug effects
topics (OpenAlex): Hypothalamic control of reproductive hormones; Neuroendocrine regulation and behavior; Estrogen and related hormone effects
TL;DR: Data suggest that BPA-induced premature puberty results from decreased inhibition of GnRH neurons, which are critical for initiating puberty and maintaining estrous cyclicity by stimulating gonadotropin-releasing hormone (GnRH) release. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 article

Sexual Phenotype Differences in zic2 mRNA Abundance in the Preoptic Area of a Protogynous Teleost, Thalassoma bifasciatum

McCaffrey, K., Hawkins, M. B., & Godwin, J. (2011, August 3). PLoS ONE, Vol. 6.

By: K. McCaffrey n, M. Hawkins n & J. Godwin n 

MeSH headings : Animals; Female; Fishes / genetics; Fishes / metabolism; Hypothalamus / metabolism; Male; RNA, Messenger / genetics; Sexual Behavior, Animal / physiology; Transcription Factors / genetics
topics (OpenAlex): Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities; Animal Behavior and Reproduction; Reproductive biology and impacts on aquatic species
TL;DR: Sexual phenotype differences in abundances of zic2 mRNA in the preoptic area of the hypothalamus, a region strongly implicated in sexual behavior and function, in an adult teleost, Thalassoma bifasciatum is described. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2026) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.