Kenneth Adler Muthusamy, N., Williams, T. I., O'Toole, R., Brudvig, J. J., Adler, K. B., Weimer, J. M., … Ghashghaei, H. T. (2022, January 24). Phosphorylation-dependent proteome of Marcks in ependyma during aging and behavioral homeostasis in the mouse forebrain. GEROSCIENCE, Vol. 1. https://doi.org/10.1007/s11357-022-00517-3 Dinh, P.-U. C., Paudel, D., Brochu, H., Popowski, K. D., Gracieux, M. C., Cores, J., … Cheng, K. (2020). Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis. NATURE COMMUNICATIONS, 11(1). https://doi.org/10.1038/s41467-020-14344-7 Sheats, M. K., Yin, Q., Fang, S., Park, J., Crews, A. L., Parikh, I., … Adler, K. B. (2019). [Review of MARCKS and Lung Disease]. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 60(1), 16–27. https://doi.org/10.1165/rcmb.2018-0285TR Adler, K. B. (2018). Does transforming growth factor-beta induce persistent airway obstruction after asthma exacerbations? American Journal of Respiratory Cell and Molecular Biology, 58(5), 543–544. https://doi.org/10.1165/rcmb.2017-0339ed Brudvig, J. J., Cain, J. T., Sears, R. M., Schmidt-Grimminger, G. G., Wittchen, E. S., Adler, K. B., … Weimer, J. M. (2018). MARCKS regulates neuritogenesis and interacts with a CDC42 signaling network. SCIENTIFIC REPORTS, 8. https://doi.org/10.1038/s41598-018-31578-0 Dinh, P.-U. C., Cores, J., Hensley, M. T., Vandergriff, A. C., Tang, J., Allen, T. A., … Cheng, K. (2017). Derivation of therapeutic lung spheroid cells from minimally invasive transbronchial pulmonary biopsies. Respiratory Research, 18(1). https://doi.org/10.1186/s12931-017-0611-0 Yin, Q., Fang, S., Park, J., Crews, A. L., Parikh, I., & Adler, K. B. (2016). An Inhaled Inhibitor of Myristoylated Alanine-Rich C Kinase Substrate Reverses LPS-Induced Acute Lung Injury in Mice. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 55(5), 617–622. https://doi.org/10.1165/rcmb.2016-0236rc Muthusamy, N., Sommerville, L. J., Moeser, A. J., Stumpo, D. J., Sannes, P., Adler, K., … Ghashghaei, H. T. (2015). MARCKS-dependent mucin clearance and lipid metabolism in ependymal cells are required for maintenance of forebrain homeostasis during aging. AGING CELL, 14(5), 764–773. https://doi.org/10.1111/acel.12354 Chen, C.-H., Chiu, C.-L., Adler, K. B., & Wu, R. (2014, April 15). A Novel Predictor of Cancer Malignancy: Up-regulation of Myristoylated Alanine-Rich C Kinase Substrate Phosphorylation in Lung Cancer. https://doi.org/10.1164/rccm.201401-0053le Chen, C. H., Thai, P., Yoneda, K., Adler, K. B., Yang, P. C., & Wu, R. (2014). A peptide that inhibits function of Myristoylated Alanine-Rich C Kinase Substrate (MARCKS) reduces lung cancer metastasis. Oncogene, 33(28), 3696–3706. https://doi.org/10.1038/onc.2013.336 Parikh, I., Long, W. A., Yin, Q., Fang, S., & Adler, K. B. (2014). Aerosolized MANS and BIO-11006 Peptides Inhibit Lung Cancer Metastasis in SCID Mice. International Journal of Radiation Oncology*Biology*Physics, 90(5), S51. https://doi.org/10.1016/J.IJROBP.2014.08.247 Sheats, M. K., Sung, E. J., Adler, K. B., Jones, S. L., & Inflammation. (2014). In Vitro Neutrophil Migration Requires Protein Kinase C-Delta (δ-PKC)-Mediated Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) Phosphorylation. Inflammation, 38(3), 1126–1141. https://doi.org/10.1007/s10753-014-0078-9 Sheats, M. K., Pescosolido, K. C., Hefner, E. M., Sung, E. J., Adler, K. B., & Jones, S. L. (2014). Myristoylated Alanine Rich C Kinase Substrate (MARCKS) is essential to β2-integrin dependent responses of equine neutrophils. Veterinary Immunology and Immunopathology, 160(3-4), 167–176. https://doi.org/10.1016/j.vetimm.2014.04.009 Chen, C.-H., Statt, S., Chiu, C.-L., Thai, P., Arif, M., Adler, K. B., & Wu, R. (2014). Targeting Myristoylated Alanine-Rich C Kinase Substrate Phosphorylation Site Domain in Lung Cancer Mechanisms and Therapeutic Implications. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 190(10), 1127–1138. https://doi.org/10.1164/rccm.201408-1505oc Adler, K. B., Shapiro, S. D., Holtzman, M. J., & McDonald, J. A. (2014, May). The Red Journal at 25 Years Looking Back and Looking Ahead. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, Vol. 50, pp. 839–840. https://doi.org/10.1165/rcmb.2014-0104ed Li, J., D’Annibale-Tolhurst, M. A., Adler, K. B., Fang, S., Yin, Q., Birkenheuer, A. J., … Nordone, S. K. (2013). A Myristoylated Alanine-Rich C Kinase Substrate–Related Peptide Suppresses Cytokine mRNA and Protein Expression in LPS-Activated Canine Neutrophils. American Journal of Respiratory Cell and Molecular Biology, 48(3), 314–321. https://doi.org/10.1165/rcmb.2012-0278oc Ott, L. E., Sung, E. J., Melvin, A. T., Sheats, M. K., Haugh, J. M., Adler, K. B., & Jones, S. L. (2013). Fibroblast Migration Is Regulated by Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) Protein. PLOS ONE, 8(6). https://doi.org/10.1371/journal.pone.0066512 Newcomb, D. C., Boswell, M. G., Sherrill, T. P., Polosukhin, V. V., Boyd, K. L., Goleniewska, K., … Peebles, S., Jr. (2013). IL-17A Induces Signal Transducers and Activators of Transcription-6-Independent Airway Mucous Cell Metaplasia. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 48(6), 711–716. https://doi.org/10.1165/rcmb.2013-0017oc Fang, S., Crews, A. L., Chen, W., Park, J., Yin, Q., Ren, X.-R., & Adler, K. B. (2013). MARCKS and HSP70 interactions regulate mucin secretion by human airway epithelial cells in vitro. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 304(8), L511–L518. https://doi.org/10.1152/ajplung.00337.2012 Lampe, W. R., Park, J., Fang, S., Crews, A. L., & Adler, K. B. (2012). Calpain and MARCKS protein regulation of airway mucin secretion. PULMONARY PHARMACOLOGY & THERAPEUTICS, 25(6), 427–431. https://doi.org/10.1016/j.pupt.2012.06.003 Green, T. D., Park, J., Yin, Q., Fang, S., Crews, A. L., Jones, S. L., & Adler, K. B. (2012). Directed migration of mouse macrophages in vitro involves myristoylated alanine-rich C-kinase substrate (MARCKS) protein. Journal of Leukocyte Biology, 92(3), 633–639. https://doi.org/10.1189/jlb.1211604 Boswell, M. G., Newcomb, D. C., Goleniewska, K., Reiss, S., Adler, K. B., & Peebles, R. S., Jr. (2012). IL-17A-mediated STAT6 Independent Mucus Production in Mice. Journal of Allergy and Clinical Immunology, 129(2), AB199. https://doi.org/10.1016/j.jaci.2011.12.308 Seibold, M. A., Wise, A. L., Speer, M. C., Steele, M. P., Brown, K. K., Loyd, J. E., … Schwartz, D. A. (2011). A Common MUC5B Promoter Polymorphism and Pulmonary Fibrosis. NEW ENGLAND JOURNAL OF MEDICINE, 364(16), 1503–1512. https://doi.org/10.1056/nejmoa1013660 Raiford, K. L., Park, J., Lin, K.-W., Fang, S., Crews, A. L., & Adler, K. B. (2011). Mucin granule-associated proteins in human bronchial epithelial cells: the airway goblet cell "granulome". RESPIRATORY RESEARCH, 12. https://doi.org/10.1186/1465-9921-12-118 Green, T. D., Crews, A. L., Park, J., Fang, S., & Adler, K. B. (2011). [Review of Regulation of mucin secretion and inflammation in asthma: A role for MARCKS protein?]. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1810(11), 1110–1113. https://doi.org/10.1016/j.bbagen.2011.01.009 Ott, L. E., Mcdowell, Z. T., Turner, P. M., Law, J. M., Adler, K. B., Yoder, J. A., & Jones, S. L. (2011). Two Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) Paralogs are Required for Normal Development in Zebrafish. The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology, 294(9), 1511–1524. https://doi.org/10.1002/ar.21453 Lin, K.-W., Fang, S., Park, J., Crews, A. L., & Adler, K. B. (2010). MARCKS and Related Chaperones Bind to Unconventional Myosin V Isoforms in Airway Epithelial Cells. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 43(2), 131–136. https://doi.org/10.1165/rcmb.2010-0016rc Foster, W. M., Adler, K. B., Crews, A. L., Potts, E. N., Fischer, B. M., & Voynow, J. A. (2010, September). MARCKS-related peptide modulates in vivo the secretion of airway Muc5ac (Retracted article. See vol. 309, pg. L 750, 2015). AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, Vol. 299, pp. L345–L352. https://doi.org/10.1152/ajplung.00067.2010 Miller, J. D., Lankford, S. M., Adler, K. B., & Brody, A. R. (2010). Mesenchymal Stem Cells Require MARCKS Protein for Directed ChemotaxisIn Vitro. American Journal of Respiratory Cell and Molecular Biology, 43(3), 253–258. https://doi.org/10.1165/rcmb.2010-0015rc Eckert, R. E., Neuder, L. E., Park, J., Adler, K. B., & Jones, S. L. (2010). Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) Protein Regulation of Human Neutrophil Migration. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 42(5), 586–594. https://doi.org/10.1165/rcmb.2008-0394oc Adler, K. B., & Abraham, E. (2009, August). Changes in NIH Review Procedures Strengths and Weaknesses. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, Vol. 41, pp. 127–128. https://doi.org/10.1165/rcmb.2009-0201ed Adler, K. B., & Abraham, E. (2009, August 1). Changes in NIH Review Procedures Strengths and Weaknesses. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 180, pp. 197–197. https://doi.org/10.1164/rccm.200906-0868ed Adler, K. B., & Matalon, S. (2009). Highlights of the August issue. American Journal of Respiratory Cell and Molecular Biology, 41(2), 125–126. https://doi.org/10.1165/rcmb.2009-2008ed Adler, K. B., & Matalon, S. (2009). Highlights of the July Issue. American Journal of Respiratory Cell and Molecular Biology, 41(1), 1–2. https://doi.org/10.1165/rcmb.2009-2007ed Crews, A. L., Potts, E., Voynow, J. A., Fischer, B. M., Bumgardner, S., Adler, K. B., & Foster, W. M. (2008). A MARCKS-related peptide attenuates both mucin hypersecretion and inflammatory cell infiltration in an elastase model of chronic bronchitis. American Journal of Respiratory and Critical Care Medicine, Vol. 177, p. A332. Wang, Y., Adler, K., Slade, D. J., Church, T. D., Webb, R. F., Chu, H. W., … Kraft, M. (2008). A MARCKS-related peptide inhibits MUC5AC expression in airway epithelial cells isolated from asthmatic subjects. American Journal of Respiratory and Critical Care Medicine, Vol. 177, p. A814. Park, J. J., Crews, A. L., Alper, S., Schwartz, D. A., & Adler, K. B. (2008). A potential role for airway epithelial cell mucin genes in fibrogenesis. American Journal of Respiratory and Critical Care Medicine, Vol. 177, p. A727. Raiford, K. L., & Adler, K. B. (2008). A proteomic analysis of proteins associated with mucin granule membranes within airway epithelial cells. American Journal of Respiratory and Critical Care Medicine, Vol. 177, p. A993. Adler, K. B. (2008, October). After 20 years, what next for the Red journal? AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, Vol. 39, pp. III-IV. https://doi.org/10.1165/rcmb.2008-0005ed Waterman, J. T., Jones, J. N., & Adler, K. B. (2008). Albuterol-induced oxidant stress in primary cultures of normal human bronchial epithelial cells. American Journal of Respiratory and Critical Care Medicine, Vol. 177, p. A469. Wang, X., & Adler, K. B. (2008). Epithelial brush border proteomics and associated dysfunction. 404nOtfound, 1, 27–33. Jester, W. F., Jiang, M., Zhao, H. L., J., P., I., M., T., A., … Panettieri, R. A. (2008). Inhibition of ozone-induced airway inflammation by decreasing myristoylated alanine-rich C kinase substrate function. American Journal of Respiratory and Critical Care Medicine, Vol. 177, p. A495. Lin, K. P., J. J., F., S., & Adler, K. B. (2008). MARCKS protein regulation of mucin secretion in airway epithelial cells: binding of MARCKS to chaperones and to MyosinV. American Journal of Respiratory and Critical Care Medicine, Vol. 177, p. A993. Park, J. J., Fang, S., Crews, A. L., Lin, K.-W., & Adler, K. B. (2008). MARCKS regulation of mucin secretion by airway epithelial cells in vitro: interactions with chaperone proteins. American Journal of Respiratory Cell and Molecular Biology, 102, 949–955. Park, J., Fang, S. J., Crews, A. L., Lin, K. W., & Adler, K. B. (2008). MARCKS regulation of mucin secretion by airway epithelium in vitro - Interaction with chaperones. American Journal of Respiratory Cell and Molecular Biology, 39(1), 68–76. https://doi.org/10.1165/rcm6.2007-0139OC Kraft, M., Adler, K. B., Ingram, J. L., Crews, A. L., Atkinson, T. P., Cairns, C. B., … Chu, H. W. (2008). Mycoplasma pneumoniae increases airway epithelial cell MUC5AC expression in asthma. European Respiratory Journal, 34, 43–46. Kraft, M., Adler, K. B., Ingram, J. L., Crews, A. L., Atkinson, T. P., Cairns, C. B., … Chu, H. W. (2008). Mycoplasma pneumoniae induces airway epithelial cell expression of MUC5AC in asthma. EUROPEAN RESPIRATORY JOURNAL, 31(1), 43–46. https://doi.org/10.1183/09031936.00103307 Waterman, J. T., & Adler, K. B. (2008). [Review of Oxidant stress and airway epithelial function]. Free radical effects on membranes, 61, 243–255. Lin, K.-W., Park, J., Crews, A. L., Li, Y., & Adler, K. B. (2008). [Review of Protease-activated receptor-2 (PAR-2) is a weak enhancer of mucin secretion by human bronchial epithelial cells in vitro]. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 40(6-7), 1379–1388. https://doi.org/10.1016/j.biocel.2007.10.031 Wang, Y. L., Bai, C., Li, K., Adler, K. B., & Wang, X. (2008). [Review of Role of airway epithelial cells in development of asthma and allergic rhinitis]. RESPIRATORY MEDICINE, 102(7), 949–955. https://doi.org/10.1016/j.rmed.2008.01.017 Green, T. D., Eckert, B. S., Sharief, Y., Crews, A. L., Adler, K. B., & Jones, S. L. (2007). A peptide against the N-terminus of MARCKS protein attenuates leukocyte migration. 404nOtfound, Vol. 175, p. A915. Park, J. J., Takashi, S., Crews, A. L., Miller-Larsson, A., & Adler, K. B. (2007). Anti-inflammatory effects of budesonide and formoterol in primary cultures of human airway epithelial cells. 404nOtfound, Vol. 175, p. A178. Agrawal, A., Rengarajan, S., Adler, K. B., Ram, A., Ghosh, B., Fahim, M., & Dickey, B. F. (2007). Inhibition of mucin secretion with MARCKS-related peptide improves airway obstruction in a mouse model of asthma. JOURNAL OF APPLIED PHYSIOLOGY, 102(1), 399–405. https://doi.org/10.1152/japplphysiol.00630.2006 Li, Y.-H., Martin, L. D., & Adler, K. B. (2007). Method and compositions for altering mucus secretion. Washington, DC: U.S. Patent and Trademark Office. Kraft, M., Nijira Lugogo, H. W., Adler, K. B., Crews, A. L., Moss, T. A., Stalls, M. A., … Chu, H. W. (2007). Mycoplasma pneumoniae increases airway epithelial cell MUC5AC expression in asthma. 404nOtfound, Vol. 175, p. A324. Park, J.-A., & Adler, K. B. (2007). Potential therapy for mucus hypersecretion in COPD. 404nOtfound, 3, 66–71. https://doi.org/10.1080/17471060601063231 Park, J.-A., Crews, A. L., Lampe, W. R., Fang, S., Park, J., & Adler, K. B. (2007). Protein kinase C delta regulates airway mucin secretion via phosphorylation of MARCKS protein. AMERICAN JOURNAL OF PATHOLOGY, 171(6), 1822–1830. https://doi.org/10.2353/ajpath.2007.070318 Park, J. A., Crews, A. L., & Adler, K. B. (2007). Protein kinase C delta regulates airway mucin secretion via phosphorylation of MARCKS protein. 404nOtfound, Vol. 175, p. A752. Raiford, K. L., Lin, K. W., Park, J., Fang, S., Crews, A. L., & Adler, K. B. (2007). Proteomic analysis of mucin granule membrane-associated proteins in human airway epithelial cells: a mechanistic link between MARCKS and hClCA1? 404nOtfound, Vol. 175, p. A511. Hawkins, E. C., Birkenheuer, A. J., Marr, H. S., Rogala, A. R., Large, E. E., & Adler, K. B. (2007). Quantification of mucin gene expression in tracheobronchial epithelium of healthy dogs and dogs with chronic bronchitis. AMERICAN JOURNAL OF VETERINARY RESEARCH, 68(4), 435–440. https://doi.org/10.2460/ajvr.68.4.435 Wang, X., Adler, K. B., Erjefalt, J., & Bai, C. (2007). Role of airway epithelial dysfunction in development of acute lung injury and acute respiratory distress syndrome. 404nOtfound, 1, 149–155. https://doi.org/10.1586/17476348.1.1.149 Waterman, J. T., Park, J. A., Crews, A. L., & Adler, K. B. (2007). The (S)?enantiomer of albuterol activates expression of iNOS via activation of NF-kB in primary cultures of normal human bronchial epithelial cells. 404nOtfound, Vol. 175, p. A178. Chorley, B. N., Li, Y. H., Fang, S. J., Park, J. A., & Adler, K. B. (2006). (R)-Albuterol elicits antiinflammatory effects in human airway epithelial cells via iNOS. American Journal of Respiratory Cell and Molecular Biology, 34(1), 119–127. https://doi.org/10.1165/rcmb.2005-03380C Takashi, S., Park, J., Fang, S., Koyama, S., Parikh, I., & Adler, K. B. (2006). A peptide against the N-terminus of myristoylated alanine-rich C kinase substrate inhibits degranulation of human leukocytes in vitro. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 34(6), 647–652. https://doi.org/10.1165/rcmb.2006-0030RC Wang, X. D., Adler, K. B., Chaudry, I. H., & Ward, P. A. (2006). Better understanding of organ dysfunction requires proteomic involvement. JOURNAL OF PROTEOME RESEARCH, 5(5), 1060–1062. https://doi.org/10.1021/pr050441n Chorley, B. N., Crews, A. L., Li, Y. H., Adler, K. B., Minnicozzi, M., & Martin, L. D. (2006). Differential Muc2 and Muc5ac secretion by stimulated guinea pig tracheal epithelial cells in vitro. Respiratory Research, 7, 35. Zhao, H., Adler, K. B., Bai, C. X., Tang, F. D., & Wang, X. D. (2006). [Review of Epithelial proteomics in multiple organs and tissues: Similarities and variations between cells, organs, and diseases]. JOURNAL OF PROTEOME RESEARCH, 5(4), 743–755. https://doi.org/10.1021/pr050389v Agrawal, A., Subramannian, R., Adler, K. B., Ram, A., Ghosh, B., Farim, M., & Dickey, B. F. (2006). MARCKS related peptide improves airway obstruction related to mucus secretion in a mouse model of asthma. 404nOtfound, Vol. 3, p. A713. Adler, K. B., Fang, S., Lin, K.-W., & Park, J. (2006). Mechanisms of mucus secretion in the airways. 404nOtfound, 2, 24–29. https://doi.org/10.1080/17471060500462450 Takashi, S., Parikh, I., Adler, K. B., Martin, L. D., & Y., L. (2006). Methods for regulating inflammatory mediators and peptides useful therein. Washington, DC: U.S. Patent and Trademark Office. Park, J. A., & Adler, K. B. (2006). Potential therapy for mucus hypersecretion in chronic obstructive pulmonary disease [translated into Chinese]. 404nOtfound, 86, 2890–2892. Park, J., Fang, S., & Adler, K. B. (2006). Regulation of airway mucin secretion by MARCKS protein involves the chaperones heat shock protein 70 and Cysteine string protein. 404nOtfound, Vol. 3, p. 493a. https://doi.org/10.1513/pats.200603-067ms Chorley, B. N., & Adler, K. B. (2005). ?2-adrenergic receptor activation with (R)-albuterol attenuates GM-CSF expression via an iNOS-mediated pathway in human bronchial epithelial cells in vitro. 404nOtfound, Vol. 2, p. A757. Takashi, S., Pettersen, C. A., Park, J., Fang, S., Akley, N. J., & Adler, K. B. (2005). A peptide directed against the N-terminus of MARCKS protein attenuates release of myeloperoxidase (MPO) from human and canine neutrophils in vitro. 404nOtfound, Vol. 2, p. A633. Martin, L. D., Adler, K. B., Macchione, M., Akley, N. J., & McKane, S. A. (2005). Culture system for mouse tracheal epithelial cells. Washington, DC: U.S. Patent and Trademark Office. Park, J., Fang, S., & Adler, K. B. (2005). Cysteine String Protein is involved in mucin secretion from normal human bronchial epithelial (NHBE) cells in vitro. 404nOtfound, Vol. 2, p. A215. Adler, K. B. (2005). Expert's opinion on potential role of epithelial cells in pathogenesis of organ dysfunction. Journal of Organ Dysfunction, 1(1), 24–25. https://doi.org/10.1080/17471060500219652 Park, J.-A., Chorley, B. N., & Adler, K. B. (2005). Human Neutrophil Elastase provokes mucin secretion by NHBE cells via a Protein Kinase C delta (PKC?)?mediated mechanism. 404nOtfound, Vol. 2, p. A110. Park, J. A., He, F., Martin, L. D., Li, Y. H., Chorley, B. N., & Adler, K. B. (2005). Human neutrophil elastase induces hypersecretion of mucin from well-differentiated human bronchial epithelial cells in vitro via a protein kinase C delta-mediated mechanism. AMERICAN JOURNAL OF PATHOLOGY, 167(3), 651–661. https://doi.org/10.1016/S0002-9440(10)62040-8 Singer, M., Martin, L. D., Vargaftig, B. B., Park, J., Gruber, A. D., Li, Y. H., & Adler, K. B. (2004). A MARCKS-related peptide blocks mucus hypersecretion in a mouse model of asthma. NATURE MEDICINE, 10(2), 193–196. https://doi.org/10.1038/nm983 Martin, L. D., Adler, K. B., & Li, Y. (2004). Blocking peptide for inflammatory cell secretion. Washington, DC: U.S. Patent and Trademark Office. Chorley, B. N., & Adler, K. B. (2004). Inducible nitric oxide synthase/protein kinase G signaling pathway suppresses granulocyte macrophage colony stimulating factor transcription in normal human bronchial epithelial cells in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 169, p. A421. Park, J., Fang, S., Gruber, A. D., & Adler, K. B. (2004). MARCKS protein interaction with the ?secretory module? regulates airway mucin secretion. American Journal of Respiratory and Critical Care Medicine, Vol. 169, p. A535. Hashimoto, K., Graham, B. S., Ho, S. B., Adler, K. B., Collins, R. D., Olson, S. J., … Peebles, R. S. (2004). Respiratory syncytial virus in allergic lung inflammation increases Muc5ac and Gob-5. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 170(3), 306–312. https://doi.org/10.1164/rccm.200301-030OC Fang, S., Park, J., & Adler, K. B. (2004). Small interfering RNA?s directed against MARCKS protein and Heat Shock Protein 70 (Hsp70) attenuate mucin secretion in human airway epithelial cells in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 169, p. A712. Vargaftig, B., Singer, M., Martin, L. D., Li, Y., & Adler, K. B. (2003). A myristoylated peptide directed against the N-terminal region of MARCKS protein inhibits mucin secretion in ovalbumin sensitized/challenged mice in vivo. American Journal of Respiratory and Critical Care Medicine, Vol. 167, p. A17. Lin, K. W., Park, J. J., Li, Y., & Adler, K. B. (2003). Activation of protease-activated receptors?2 (PAR-2) is not associated with enhanced mucin secretion by well-differentiated normal human bronchial epithelial cells in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 167, p. A204. Chorley, B. N., Martin, L. D., Crews, A. C., Li, Y., & Adler, K. B. (2003). Differential effects of albuterol isomers on normal human bronchial epithelial cells in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 167, p. A205. Krunkosky, T. M., Martin, L. D., Fischer, B. M., Voynow, J. A., & Adler, K. B. (2003). Effects of TNF alpha on expression of ICAM-1 in human airway epithelial cells in vitro: Oxidant-mediated pathways and transcription factors. FREE RADICAL BIOLOGY AND MEDICINE, 35(9), 1158–1167. https://doi.org/10.1016/S0891-5849(03)00498-2 Park, J. A., He, F., Li, Y., Martin, L. D., & Adler, K. B. (2003). Human neutrophil elastase provokes release of MUC5B mucin from normal bronchial epithelial cells in vitro via a PKC-dependent mechanism. American Journal of Respiratory and Critical Care Medicine, Vol. 167, p. A203. Singh, P., Daniels, M., Winsett, D. W., Richards, J., Doerfler, D., Hatch, G., … Gilmour, M. I. (2003). Phenotypic comparison of allergic airway responses to house dust mite in three rat strains. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 284(4), L588–L598. https://doi.org/10.1152/ajplung.00287.2002 Booth, B. W., Newcomb, D. C., McKane, S. A., Crews, A. L., Adler, K. B., Bonner, J. C., & Martin, L. D. (2003, March). Proliferation of the airway epithelium in asthma - Are inflammatory cells required? CHEST, Vol. 123, pp. 384S–385S. https://doi.org/10.1378/chest.123.3_suppl.384S Hashimoto, K., Graham, B. S., Ho, S. B., Adler, K. B., Collins, R. D., Jones, P. W., … Peebles, R. S., Jr. (2003). Respiratory syncytial virus infection upregulates Muc5ac and gob-5 lung protein expression only in the setting of allergic inflammation. American Journal of Respiratory and Critical Care Medicine, Vol. 167, p. A425. Singh, P., Dick, C. A., Boykin, E., Andrews, D., Adler, K. B., & Gilmour, I. (2003). Role of oxidative stress and p38MAP kinase in murine pulmonary responses to LPS and diesel exhaust particles. American Journal of Respiratory and Critical Care Medicine, Vol. 167, p. A622. Pettersen, C. A., & Adler, K. B. (2002, May). Airways inflammation and COPD - Epithelial-neutrophil interactions. CHEST, Vol. 121, pp. 142S–150S. https://doi.org/10.1378/chest.121.5_suppl.142S Singh, P., Daniels, M. J., Winsett, D., Richards, J., Bishop, L., Dick, C. A. J., … Gilmour, M. I. (2002). Diesel exhaust particles increase lung injury and inflammation during early sensitization in brown Norway rats. Toxicological Sciences, Vol. 66, p. 147. Singh, P., Winsett, D. W., Daniels, M. J., Dick, C. A. J., Adler, K. B., & Gilmour, M. I. (2002). Effects of allergic airways disease on influenza virus infection in brown Norway rats. American Journal of Respiratory and Critical Care Medicine, Vol. 165, p. A183. Booth, B. W., Adler, K. B., & Martin, L. D. (2002). IL-13 induces intracellular translocation and release of TGF? in human bronchial epithelial cells in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 165, p. A814. Martin, L. D., Adler, K. B., Akley, N. J., Crews, A., & Sharova, L. (2002). Secretion-competent mouse tracheal epithelial cell culture from the genetically altered mouse - Pathway analysis via gene array. Chest, 121(3), 79S. https://doi.org/10.1016/S0012-3692(15)35478-7 Adler, K. B., & Li, Y. H. (2001). Airway epithelium and mucus - Intracellular signaling pathways for gene expression and secretion. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 25(4), 397–400. https://doi.org/10.1165/ajrcmb.25.4.f214 Booth, B., Bonner, J. C., Adler, K. B., & Martin, L. D. (2001). Autocrine production of TGFa mediates interleukin 13-induced proliferation of human airway epithelial cells during development of a mucous phenotype in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 163, p. A738. Macchione, M., Akley, N. J., Adler, K. B., & Martin, L. D. (2001). Differentiation of murine tracheal epithelial cells in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 163, p. A225. Li, Y. H., Martin, L. D., Minnicozzi, M., Greenfeder, S., Fine, J., Pettersen, C. A., … Adler, K. B. (2001). Enhanced expression of mucin genes in a guinea pig model of allergic asthma. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 25(5), 644–651. https://doi.org/10.1165/ajrcmb.25.5.4485 Martin, L. D., Macchione, M., Bonner, J. C., Booth, B. W., Akley, N. J., & Adler, K. B. (2001). Interleukin-13 induced mucous cell hyperplasia in airway epithelium. In Cilia and mucus: from development to respiratory disease. (pp. 253–263). Booth, B. W., Adler, K. B., Bonner, J. C., Tournier, F., & Martin, L. D. (2001). Interleukin-13 induces proliferation of human airway epithelial cells in vitro via a mechanism mediated by transforming growth factor-alpha. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 25(6), 739–743. https://doi.org/10.1165/ajrcmb.25.6.4659 Booth, B., Bonner, J., Akley, N., Macchione, M., Adler, K., & Martin, L. D. (2001, July). Interleukin-13, a mediator of subepithelial fibrosis, enhances growth factor production and proliferation in human airway epithelial cells. CHEST, Vol. 120, pp. 15S–15S. https://doi.org/10.1378/chest.120.1_suppl.S15 Li, Y., Pettersen, C. A., Martin, L. D., & Adler, K. B. (2001). MARCKS protein interaction with the cellular contractile machinery may regulate mucin secretion by human airway epithelium. American Journal of Respiratory and Critical Care Medicine, Vol. 163, p. A225. Li, Y. H., Martin, L. D., Spizz, G., & Adler, K. B. (2001). MARCKS protein is a key molecule regulating mucin secretion by human airway epithelial cells in vitro. JOURNAL OF BIOLOGICAL CHEMISTRY, 276(44), 40982–40990. https://doi.org/10.1074/jbc.M105614200 Li, Y., Martin, L. D., & Adler, K. B. (2001). MARCKS protein: a potential modulator of airway mucin secretion. In Cilia and mucus: from development to respiratory disease. (pp. 179–193). Bonner, J. C., Wang, Y. Z., Zhang, P., Rice, A., Zhang, L. M., Adler, K., … Kagan, E. (2001, July). Role of receptor tyrosine kinases and mitogen-activated protein kinases in metal-induced pulmonary fibrosis. CHEST, Vol. 120, pp. 55S–56S. https://doi.org/10.1378/chest.120.1_suppl.S55 Zhang, L. M., Rice, A. B., Adler, K., Sannes, P., Martin, L., Gladwell, W., … Bonner, J. C. (2001). Vanadium stimulates human bronchial epithelial cells to produce heparin-binding epidermal growth factor-like growth factor - A mitogen for lung fibroblasts. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 24(2), 123–131. https://doi.org/10.1165/ajrcmb.24.2.4096 He, F., Adler, K. B., Akley, N. J., Fischer, B. M., Jiang, N., Krunkosky, T. M., & Martin, L. D. (2000). Air-liquid interface culture systems for exposure of differentiated cells to oxidant stress. In Models and methods in cell signaling and gene expression applications to oxidative stress research. (pp. 15–30). Martin, L. D., Krunkosky, T. M., & Adler, K. B. (2000). Differential generation of intracellular oxidants by TNF? and exogenous superoxide affords distinct expression of IL-6 in human airway epithelium in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 161, p. A152. Krunkosky, T. M., Fischer, B. M., Martin, L. D., Jones, N., Akley, N. J., & Adler, K. B. (2000). Effects of TNF-alpha on expression of ICAM-1 in human airway epithelial cells in vitro - Signaling pathways controlling surface and gene expression. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 22(6), 685–692. https://doi.org/10.1165/ajrcmb.22.6.3925 Bonner, J. C., Zhang, L., Sannes, P., Martin, L., Gladwell, W., Koo, J.-S., … Adler, K. (2000). Induction of heparin-binding epidermal growth factor (HB-EGF) mRNA in normal human bronchial epithelial cells by metal-induced oxidative stress. American Journal of Respiratory and Critical Care Medicine, Vol. 161, p. A149. Martin, L. D., Bonner, J. C., Macchione, M., Booth, B., Akley, N., & Adler, K. B. (2000). Interaction of TGF? and EGF receptor mediates IL-13 induced mucous cell hyperplasia in human airway epithelium in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 161, p. A779. Li, Y., Martin, L. D., & Adler, K. B. (2000). MARCKS protein: a key intracellular molecule controlling mucin secretion by human airway goblet cells. American Journal of Respiratory and Critical Care Medicine, Vol. 161, p. A259. He, F., Martin, L. D., & Adler, K. B. (2000). Mechanisms of human neutrophil elastase-induced mucin hypersecretion by human airway epithelial cells in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 161, p. A155. Adler, K. B., Li, Y., & Martin, L. D. (2000). Myristoylated alanine-rich C-kinase substrate protein: A major intracellular regulatory molecule controlling secretion of mucin by human airway goblet cells. Chest, Vol. 117, pp. 266S–267S. Jiang, N. F., Dreher, K. L., Dye, J. A., Li, Y. H., Richards, J. H., Martin, L. D., & Adler, K. B. (2000). Residual oil fly ash induces cytotoxicity and mucin secretion by guinea pig tracheal epithelial cells via an oxidant-mediated mechanism. TOXICOLOGY AND APPLIED PHARMACOLOGY, 163(3), 221–230. https://doi.org/10.1006/taap.1999.8886 Martin, L. D., Norford, D., Voynow, J., & Adler, K. B. (2000, May). Response of human airway epithelium in vitro to inflammatory mediators - Dependence on the state of cellular differentiation. CHEST, Vol. 117, pp. 267S–267S. https://doi.org/10.1378/chest.117.5_suppl_1.267s Li, Y., Greenfeder, S., Martin, L. D., Minnicozzi, M., Voynow, J. A., & Adler, K. B. (1999). Cloning and expression of guinea pig MUC2 and MUC5AC genes. American Journal of Respiratory and Critical Care Medicine, Vol. 159, p. A852. Li, C. M., Joshee, N., Adler, K. B., & Cheng, P. W. (1999). Development of monoclonal antibodies against bovine mucin core 2 beta 6 N-acetylglucosaminyltransferase. GLYCOCONJUGATE JOURNAL, 16(9), 555–562. https://doi.org/10.1023/A:1007030223118 Li, Y., He, F., Martin, L. D., Krunkosky, T. M., Lincoln, T. M., Cornwell, T. L., & Adler, K. B. (1999). Myristoylated alanine-rich C kinase substrate (MARCKS) is produced by human airway epithelial cells and is phosphorylated by PKC and PKG. American Journal of Respiratory and Critical Care Medicine, Vol. 159, p. A723. Zhang, L., Adler, K. B., Sannes, P., & Bonner, J. C. (1999). Normal human bronchial epithelial cells produce heparin-binding epidermal growth factor (HB-EGF), a mitogen for human lung fibroblasts in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 159, p. A508. Dye, J. A., Adler, K. B., Richards, J. H., & Dreher, K. L. (1999). Role of soluble metals in oil fly ash-induced airway epithelial injury and cytokine gene expression. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 277(3), L498–L510. https://doi.org/10.1152/ajplung.1999.277.3.l498 Adler, K. B., Martin, L. D., Voynow, J. A., & Krunkosky, T. M. (1999). TNF? effects on human airway epithelial cells in vitro: molecular mechanisms of enhanced mucin production/secretion and ICAM-I expression. 404nOtfound, Vol. 8, p. S55. Krunkosky, T. M., Martin, L. D., Li, Y., & Adler, K. B. (1999). TNF?-induced ICAM-1 expression in airway epithelium: involvement of IkB?. American Journal of Respiratory and Critical Care Medicine, Vol. 159, p. A184. Martin, L. D., Krunkosky, T. M., & Adler, K. B. (1999). Transcription factor activation during oxidant-regulated interleukin-6 expression in normal human bronchial epithelium in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 159, p. A447. Fischer, B. M., Rochelle, L. G., Voynow, J. A., Akley, N. J., & Adler, K. B. (1999, March). Tumor necrosis factor-alpha stimulates mucin secretion and cyclic GMP production by guinea pig tracheal epithelial cells in vitro. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, Vol. 20, pp. 413–422. https://doi.org/10.1165/ajrcmb.20.3.3393 Kim, Y. S., Koo, J. S., Norford, D., Gray, T., Adler, K., & Nettesheim, P. (1999). Upregulation of mucin gene expression in airway epithelial cells by inflammatory mediators. American Journal of Respiratory and Critical Care Medicine, Vol. 159, p. A36. Li, Y., Martin, L. D., Minnicozzi, M., & Adler, K. B. (1998). Cloning of guinea pig Muc2 cDNA and MUC2 gene expression in guinea pig airway epithelium in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 157, p. A728. Rochelle, L. G., Fischer, B. M., & Adler, K. B. (1998). Concurrent production of reactive oxygen and nitrogen species by airway epithelial cells in vitro. FREE RADICAL BIOLOGY AND MEDICINE, 24(5), 863–868. https://doi.org/10.1016/S0891-5849(97)00375-4 Adler, K. B., Fischer, B. M., Martin, L. D., & Voynow, J. A. (1998). Effects of inflammatory mediators and drugs on mucus secretion and mucociliary function. 404nOtfound, 149, 245–248. Adler, K. B., Jiang, N. F., Dye, J. A., & Dreher, K. L. (1998). Exposure of differentiated rodent airway epithelial cells in vitro to particles of residual fly ash (ROFA) induces cytotoxicity and generation of reactive oxygen species. Proceedings of the 10th International Colloquium on Lung Fibrosis, Vol. 10, p. 26. Norford, D., Koo, J. S., Gray, T., Alder, K., & Nettesheim, P. (1998). Expression of nitric oxide synthase isoforms in normal human tracheobronchial epithelial cells in vitro: Dependence on retinoic acid and the state of differentiation. EXPERIMENTAL LUNG RESEARCH, 24(3), 355–366. https://doi.org/10.3109/01902149809041540 Martin, L. D., Krunkosky, T. M., Voynow, J. A., & Adler, K. B. (1998). Intracellular reactive oxygen and nitrogen species as signaling molecules in airway epithelium. Environmental Health Perspectives, 106, 1197–1203. Fischer, B. M., Li, C., Li, H., Choe, N., Wright, D. T., Rochelle, L. G., & Adler, K. B. (1998). Intracellular regulation of airway mucin secretion. In Cilia, mucus and mucociliary interactions (pp. 143–151). Krunkosky, T. M., Fischer, B. M., Dodam, J. R., & Adler, K. B. (1998). Mechanisms of TNF? signaling in airway epithelial cells in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 157, p. A198. Li, C. M., Adler, K. B., & Cheng, P. W. (1998). Mucin biosynthesis: Molecular cloning and expression of bovine lung mucin core 2 N-acetylglucosaminyltransferase cDNA. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 18(3), 343–352. https://doi.org/10.1165/ajrcmb.18.3.2593 Martin, L. D., Krunkosky, T. M., Voynow, J. A., & Adler, K. B. (1998). Oxidant-regulated gene expression in inflammatory lung disease. In Acute respiratory distress syndrome: cellular and molecular mechanisms and clinical management. (pp. 187–195). https://doi.org/10.1007/978-1-4419-8634-4_23 Adler, K. B., Jiang, N. F., Dye, J. A., & Dreher, K. L. (1998). Particles of Residual Oil Fly Ash (ROFA) induce toxicity and mucin hypersecretion in rodent airway epithelial cells in vitro via an oxidant-mediated mechanism. Toxicology Letters, Vol. 95, p. 224. https://doi.org/10.1016/s0378-4274(98)80888-6 Norford, D., Koo, J. S., Gray, T., & Adler, K. B. (1998). Regulation of nitric oxide synthase (NOS) isoforms in human tracheobronchial cells by retinoic acid. American Journal of Respiratory and Critical Care Medicine, Vol. 157, p. A769. Jiang, N.-F., Dreher, K. L., & Adler, K. B. (1998). Residual oil fly ash (ROFA) induces cytotoxicity and enhances mucin secretion by guinea pig airway epithelial cells in vitro via an oxidant mediated mechanism. American Journal of Respiratory and Critical Care Medicine, Vol. 157, p. A150. Martin, L. D., Krunkosky, T. M., Voynow, J. A., & Adler, K. B. (1998, October). The role of reactive oxygen and nitrogen species in airway epithelial gene expression. ENVIRONMENTAL HEALTH PERSPECTIVES, Vol. 106, pp. 1197–1203. https://doi.org/10.2307/3433986 Dye, J. A., Adler, K. B., Rochelle, L. G., & Dreher, K. L. (1998). Vanadium content and related oxidative stress appear to determine airway epithelial cell responses to emission source particulate matter. FASEB Journal, Vol. 12, p. A337. Dye, J. A., Adler, K. B., Richards, J. H., & Dreher, K. L. (1997). Airway epithelial cell responses to fly ash (ROFA) particles: contribution of soluble transition metals. American Journal of Respiratory and Critical Care Medicine, Vol. 155, p. A197. Cohn, L. A., Fischer, B. M., & Adler, K. B. (1997). Airway epithelial cells in asthma. In Allergy and allergic diseases. (pp. 263–283). Martin, L. D., Rochelle, L. G., Fischer, B. M., Krunkosky, T. M., & Adler, K. B. (1997). [Review of Airway epithelium as an effector of inflammation: molecular regulation of secondary mediators]. EUROPEAN RESPIRATORY JOURNAL, 10(9), 2139–2146. https://doi.org/10.1183/09031936.97.10092139 Adler, K. B., Krunkosky, T. M., & Fischer, B. M. (1997). Effects of tumour necrosis factor-alpha on airway epithelial cells in vitro. 404nOtfound, Vol. 3, p. 74. Dye, J. A., Adler, K. B., Richards, J. H., & Dreher, K. L. (1997). Epithelial injury induced by exposure to residual oil fly-ash particles: Role of reactive oxygen species? AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 17(5), 625–633. https://doi.org/10.1165/ajrcmb.17.5.2749 Rochelle, L. G., Fischer, B. M., Boehm, K. A., Akley, N. J., & Adler, K. B. (1997). Inflammatory mediators increase intracellular reactive oxygen and nitrogen species (ROS/RNS) in airway epithelial cells. American Journal of Respiratory and Critical Care Medicine, Vol. 155, p. A437. Wright, D. T., Li, C. M., Fischer, B. M., Yagaloff, K., & Adler, K. B. (1997). Interactions between oxidant gases and airway epithelial cells; in vitro in vivo correlations. In Correlations between in vitro and in vivo investigations in inhalation toxicology. (pp. 216–229). Adler, K. B., Li, C. M., Li, H. F., Choe, N., & Fischer, B. M. (1997). Intracellular regulation of mucin secretion. Proceedings of the International Congress on Cilia, Mucus and Mucociliary Interations., p. 15. Krunkosky, T. M., Martin, L. D., Fischer, B. M., & Adler, K. B. (1997). Mechanisms of TNF?-induced ICAM-1 expression in airway epithelium. American Journal of Respiratory and Critical Care Medicine, Vol. 155, p. A207. Cheng, P. W., Li, C. M., & Adler, K. B. (1997). Molecular cloning and expression of a mucin core 2 N-acetylglucosaminyltransferase cDNA. American Journal of Respiratory and Critical Care Medicine, Vol. 155, p. A434. Lee, J. G., Madden, M. C., Hatch, G., Bottei, G., Peden, D., Adler, K. B., & Devlin, R. (1997). Ozone induced DNA single strand breaks in human and guinea pig lung cells in vivo. Inhalation Toxicology, 9(9), 811–828. Murphy, T. M., Akley, N. J., Chitapo, P., & Adler, K. (1997). Secretory inhibition by airway epithelium increases with age. American Journal of Respiratory and Critical Care Medicine, Vol. 155, p. A427. Martin, L. D., Krunkosky, T. M., Rochelle, L. G., & Adler, K. B. (1997). TNF? and oxidant-induced expression of Interleukin-6 in normal human bronchial epithelium in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 155, p. A206. Martin, L. D., Krunkosky, T. M., Dye, J. A., Fischer, B. M., Jiang, N. F., Rochelle, L. G., … Adler, K. B. (1997, September). The role of reactive oxygen and nitrogen species in the response of airway epithelium to particulates. ENVIRONMENTAL HEALTH PERSPECTIVES, Vol. 105, pp. 1301–1307. https://doi.org/10.2307/3433551 Adler, K. B., Menard, M., & Sannes, P. L. (1996). Airway epithelium: A primary source for growth factors related to development of fibrosis? Proceedings of the 9th International Colloquium on Lung Fibrosis, Vol. 9, p. 29. Dodam, J. R., Adler, K. B., & Olson, N. C. (1996). Effect of pertussis toxin and B-Oligomer on platelet-activating factor-induced generation of inositol phosphates in porcine alveolar macrophages. American Journal of Veterinary Research, 57, 574–579. Rochelle, L. G., Fischer, B. M., Krunkosky, T. M., Wright, D. T., & Adler, K. B. (1996, March). Environmental toxins induce intracellular responses of airway epithelium through reactive species of oxygen and nitrogen. CHEST, Vol. 109, pp. S35–S39. https://doi.org/10.1378/chest.109.3_supplement.35s Li, H., & Adler, K. B. (1996). Histamine stimulates secretion of mucin and activates phospholipase C in airway epithelium: evidence for independent pathways. American Journal of Respiratory and Critical Care Medicine, Vol. 153, p. A539. Dye, J. A., Adler, K. B., Richards, J. R., & Dreher, K. L. (1996). Injury of rat tracheal epithelial cultures by exposure to residual oil fly ash (ROFA) involves generation of the hydroxyl radical. American Journal of Respiratory and Critical Care Medicine, Vol. 153, p. A542. Allen, J. B., McGahan, M. C., Ferrell, J. B., Adler, K. B., & Fleisher, L. N. (1996). Nitric oxide synthase inhibitors exert differential time-dependent effects on LPS-induced uveitis. EXPERIMENTAL EYE RESEARCH, 62(1), 21–28. https://doi.org/10.1006/exer.1996.0003 Adler, K. B., Wright, D. T., Li, C., Li, H., Choe, N., Rochell, L. G., & Fischer, B. M. (1996). Nitric oxide: A key signaling molecule regulating airway mucin secretion. Proceedings of the 9th World Congress on Bronchology & World Congress on Bronchoesophagology., Vol. 9, p. S060. Wright, D. T., Fischer, B. M., Li, C. M., Rochelle, L. G., Akley, N. J., & Adler, K. B. (1996). Oxidant stress stimulates mucin secretion and PLG in airway epithelium via a nitric oxide-dependent mechanism. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 271(5), L854–L861. https://doi.org/10.1152/ajplung.1996.271.5.l854 Adler, K. B., Wright, D. T., & Fischer, B. M. (1996). Reactive oxygen species provoke secretion of mucin and activate phospholipase C in airway epithelial cells in vitro via a mechanism dependent on nitric oxide and hydroxyl free radical. Molecules to Man, Proceedings of Keystone Symposium, p. 20. Adler, K. B. (1996). Role of airway epithelium in airway inflammation. Proceedings of the Symposium on Airway Mucus (Seoul, 1996)., p. 32. Adler, K. B., Krunkosky, T. M., Fischer, B. M., Rochelle, L. G., Martin, L. D., Dreher, K. L., … Dye, J. (1996). Role or reactive oxygen and nitrogen species in the response of airway epithelium to particulates. Proceedings of the 6th International Meeting of the Toxicology of Natural and Man-Made Fibrous and Non-Fibrous Particles., Vol. 6, p. 139. Krunkosky, T. M., Fischer, B. M., Akley, N. J., & Adler, K. B. (1996). Tumor necrosis factor alpha (TNF alpha)-induced ICAM-1 surface expression in airway epithelial cells in vitro: Possible signal transduction mechanisms. CYTOKINES AND ADHESION MOLECULES IN LUNG INFLAMMATION, Vol. 796, pp. 30–37. https://doi.org/10.1111/j.1749-6632.1996.tb32564.x Krunkosky, T. M., Fischer, B. M., Martin, L. D., & Adler, K. B. (1996). Tumor necrosis factor alpha (TNF?) provokes expression of intercellular adhesion molecule-1 (ICAM-1) on human bronchial epithelial cells in primary culture. American Journal of Respiratory and Critical Care Medicine, Vol. 153, p. A27. Fischer, B. M., Rochelle, L. G., Akley, N. J., & Adler, K. B. (1996). Tumor necrosis factor-alpha (TNF?) induced mucin secretion: dependence on nitric oxide (NO) and cyclic GMP. American Journal of Respiratory and Critical Care Medicine, Vol. 153, p. A538. Lee, J. G., Madden, M. C., Reed, W., Adler, K. B., & Devlin, R. B. (1996). Use of the single cell gel electrophoresis assay (SCGE) for detection of oxidant-induced DNA single strand breaks (SSB) in human lung cells in vitro. Toxicology and Applied Pharmacology, 141, 195–204. https://doi.org/10.1006/taap.1996.0276 Krunkosky, T. M., Fischer, B. M., Wright, D. T., Akley, N. J., & Adler, K. B. (1995). Effects of tumor necrosis factor alpha (TNF?) on expression of ICAM-1 and inflammation-associated genes in airway epithelial cells in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 151, p. A366. Fischer, B. M., Wright, D. T., Li, H., Li, C. M., Cohn, L. A., Akley, N. J., & Adler, K. B. (1995). Endogenously-generated nitric oxide (NO) may be a key signaling molecule in hypersecretion of mucin by guinea pig tracheal epithelial (GPTE) cells in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 151, p. A337. LI, H. F., CHOE, N. H., WRIGHT, D. T., & ADLER, K. B. (1995). HISTAMINE PROVOKES TURNOVER OF INOSITOL PHOSPHOLIPIDS IN GUINEA-PIG AND HUMAN AIRWAY EPITHELIAL-CELLS VIA AN H-1-RECEPTOR G-PROTEIN-DEPENDENT MECHANISM. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 12(4), 416–424. https://doi.org/10.1165/ajrcmb.12.4.7695921 ADLER, K. B., FISCHER, B. M., LI, H. F., CHOE, N. H., & WRIGHT, D. T. (1995). HYPERSECRETION OF MUCIN IN RESPONSE TO INFLAMMATORY MEDIATORS BY GUINEA-PIG TRACHEAL EPITHELIAL-CELLS IN-VITRO IS BLOCKED BY INHIBITION OF NITRIC-OXIDE SYNTHASE. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 13(5), 526–530. https://doi.org/10.1165/ajrcmb.13.5.7576687 Lee, J. G., Madden, M. C., Hatch, G. E., Bottei, G., Reed, W., Adler, K. B., & Devlin, R. B. (1995). Ozone exposure in vivo induces increases in DNA single strand breaks in human and guinea pig lung cells. American Journal of Respiratory and Critical Care Medicine, Vol. 151, p. A498. Wright, D. T., Li, C. M., Fischer, B. M., Akley, N. J., & Adler, K. B. (1995). Reactive nitrogen species (RNS) stimulate secretion of mucin by primary cultures of guinea pig tracheal epithelial (GPTE) cells. American Journal of Respiratory and Critical Care Medicine, Vol. 151, p. A337. Fischer, B. M., Krunkosky, T. M., Wright, D. T., Dolan-O'Keefe, M., & Adler, K. B. (1995). Tumor necrosis factor alpha (TNF?) stimulates mucin secretion and gene expression in airway epithelium invitro. Chest, 107, 133S–135. https://doi.org/10.1378/chest.107.3_supplement.133s Cohn, L. A., & Adler, K. B. (1994). Alternatives to in vivo toxicological testing of rodent airway epithelia. In Animal test alternatives: refinement-reduction-replacement. (pp. 233–239). Cohn, L. A., & Adler, K. B. (1994). Antioxidant scavenging by guinea pig and human airway epithelial cells in vitro: mechanisms of H2O2 clearance. American Journal of Physiology. Lung Cellular and Molecular Physiology, 265(10), 397–404. Dye, J. A., & Adler, K. B. (1994). Effects of cigarette smoke on epithelial cells of the respiratory tract. 404nOtfound, 49, 825–834. https://doi.org/10.1136/thx.49.8.825 Adler, K. B., Wright, D. T., Fischer, B. M., Cohn, L. A., Li, C., Li, H., … Akley, N. J. (1994). Effects of oxidant stress on airway epithelial cells in vitro. FASEB Journal, Vol. 8, p. A896. Adler, K. B., Fischer, B. M., Wright, D. T., & Dolan-O'Keefe, M. (1994). Effects of tumor necrosis factor alpha (TNF?) on airway epithelial cells in vitro. Proceedings of the 8th International Colloquium on Lung Fibrosis, Vol. 8, p. 3. ADLER, K. B., FISCHER, B. M., WRIGHT, D. T., COHN, L. A., & BECKER, S. (1994). INTERACTIONS BETWEEN RESPIRATORY EPITHELIAL-CELLS AND CYTOKINES - RELATIONSHIPS TO LUNG INFLAMMATION. CELLS AND CYTOKINES IN LUNG INFLAMMATION, Vol. 725, pp. 128–145. https://doi.org/10.1111/j.1749-6632.1994.tb00275.x Wright, D. T., Cohn, L. A., Li, H., Fischer, B. M., Li, C. M., & Adler, K. B. (1994). Interactions of oxygen radicals with airway epithelium. Environmental Health Perspectives. Supplements, 102(11), 85–90. https://doi.org/10.1289/ehp.94102s1085 Wright, D. T., Friedman, M., Pryor, W. A., Squadrito, G. L., Salgo, M. G., & Adler, K. B. (1994). Lipid ozonation products activate phospholipases in guinea pig and human airway epithelial cells in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 149, p. A320. WRIGHT, D. T., ADLER, K. B., AKLEY, N. J., DAILEY, L. A., & FRIEDMAN, M. (1994). OZONE STIMULATES RELEASE OF PLATELET-ACTIVATING-FACTOR AND ACTIVATES PHOSPHOLIPASES IN GUINEA-PIG TRACHEAL EPITHELIAL-CELLS IN PRIMARY CULTURE. TOXICOLOGY AND APPLIED PHARMACOLOGY, 127(1), 27–36. https://doi.org/10.1006/taap.1994.1135 LI, C. M., CHENG, P. W., & ADLER, K. B. (1994). PRODUCTION AND CHARACTERIZATION OF MONOCLONAL-ANTIBODIES AGAINST GUINEA-PIG TRACHEAL MUCINS. HYBRIDOMA, 13(4), 281–287. https://doi.org/10.1089/hyb.1994.13.281 Choe, N.-H., Li, H., & Adler, K. B. (1994). Platelet activating factor and histamine activate phospholipase C in airway epithelial cells in vitro via a pertussis toxin sensitive G protein. American Journal of Respiratory and Critical Care Medicine, Vol. 149, p. A985. Wright, D. T., Akley, N. J., Li, H., Fischer, B. M., & Adler, K. B. (1994). Reactive oxygen species (ROS) activate phospholipase C in guinea pig and human airway epithelial cells in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 149, p. A315. Adler, K. B., Fischer, B. M., Akley, N. J., & Dolan-O'Keefe, M. (1994). Tumor necrosis factor alpha (TNF?) stimulates mucin secretion and gene expression in airway epithelium in vitro. Proceedings of the 37th Aspen Lung Conference., Vol. 37, p. 17. Lee, J. G., Madden, M. C., Reed, W., Adler, K. B., & Devlin, R. B. (1994). Use of the single cell gel electrophoresis assay (SCGE) for detection of oxidant-induced DNA single strand breaks (SSB) in human lung cells. American Journal of Respiratory and Critical Care Medicine, Vol. 149, p. A158. Cohn, L. A., & Adler, K. B. (1993). Antioxidant scavenging by guinea pig and human airway epithelial cells in vitro: mechanisms of H2O2 clearance. American Review of Respiratory Disease, Vol. 147, p. A440. KAARTINEN, L., NETTESHEIM, P., ADLER, K. B., & RANDELL, S. H. (1993). RAT TRACHEAL EPITHELIAL-CELL DIFFERENTIATION IN-VITRO. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 29A(6), 481–492. https://doi.org/10.1007/bf02639383 Cohn, L. A., Akley, N. J., & Adler, K. B. (1993). Study of xenobiotics and airway epithelium in vitro. In Fiber toxicology. (pp. 171–194). Adler, K. B., & Cohn, L. A. (1993). Use of air/liquid interface cultures to assess polarized responses of airway epithelium to toxicants. In Vitro Cellular & Developmental Biology. Animal, Vol. 29A, p. 46A. Adler, K. B. (1993). Use of air/liquid interface guinea pig tracheal epithelial cell culture system for assessment of interactions between inhaled substances and airways. Proceedings of the Toxicol Forum 1993 Annual Winter Meeting, 1993(Winter), 14–19. Adler, K. B., & Cohn, L. A. (1993). Use of air/liquid interface guinea pig tracheal epithelial cell culture systems for assessment of interactions between inhaled substances and airways. Proceedings of the Toxicology Forum 1993., Vol. 1993. Rippetoe, P. E., Absher, M., Makrides, W., Adler, K. B., & Evans, J. N. (1992). Airway epithelial cells release factor(s) that stimulate proliferation of airway smooth muscle cells in vitro. Molecular Biology of the Cell, Vol. 3, p. 175a. Adler, K. B., & Cohn, L. A. (1992). Guinea pig tracheal epithelial cells in primary air/liquid interface culture scavenge H2O2 via a mechanism only partially dependent on catalase and the glutathione system. FASEB Journal, Vol. 6, p. A939. ADLER, K. B., KINNULA, V. L., AKLEY, N., LEE, J. W., COHN, L. A., & CRAPO, J. D. (1992). INFLAMMATORY MEDIATORS AND THE GENERATION AND RELEASE OF REACTIVE OXYGEN SPECIES BY AIRWAY EPITHELIUM INVITRO. CHEST, 101(3), S53–S54. https://doi.org/10.1378/chest.101.3_supplement.53s COHN, L. A., & ADLER, K. B. (1992). [Review of INTERACTIONS BETWEEN AIRWAY EPITHELIUM AND MEDIATORS OF INFLAMMATION]. EXPERIMENTAL LUNG RESEARCH, 18(3), 299–322. https://doi.org/10.3109/01902149209031687 Friedman, M., Wright, D. T., Dailey, L. A., Akley, N. J., Devlin, R. B., & Adler, K. B. (1992). Ozone increases platelet activating factor and activates phospholipases (PLA2 and PLC) in primary guinea pig tracheal epithelial cells (GPTE). American Review of Respiratory Disease, Vol. 145, p. A99. ADLER, K. B., AKLEY, N. J., & GLASGOW, W. C. (1992). PLATELET-ACTIVATING-FACTOR PROVOKES RELEASE OF MUCIN-LIKE GLYCOPROTEINS FROM GUINEA-PIG RESPIRATORY EPITHELIAL-CELLS VIA A LIPOXYGENASE-DEPENDENT MECHANISM. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 6(5), 550–556. https://doi.org/10.1165/ajrcmb/6.5.550 KINNULA, V. L., ADLER, K. B., ACKLEY, N. J., & CRAPO, J. D. (1992). RELEASE OF REACTIVE OXYGEN SPECIES BY GUINEA-PIG TRACHEAL EPITHELIAL-CELLS INVITRO. AMERICAN JOURNAL OF PHYSIOLOGY, 262(6), L708–L712. https://doi.org/10.1152/ajplung.1992.262.6.l708 Adler, K. B., Kinnula, V., Akley, N. J., & Crapo, J. D. (1991). Airway epithelium generates and releases reactive oxygen species in response to activation of protein kinase C. Proceedings Fo the 4th International Conference on Environmental Lung Disease (Montreal, 1991), Vol. 4, p. 2. MOSSMAN, B. T., JANSSEN, Y. M., MARSH, J. P., SESKO, A., SHATOS, M. A., DOHERTY, J., … KAGAN, E. (1991). DEVELOPMENT AND CHARACTERIZATION OF A RAPID-ONSET RODENT INHALATION MODEL OF ASBESTOSIS FOR DISEASE PREVENTION. TOXICOLOGIC PATHOLOGY, Vol. 19, pp. 412–418. https://doi.org/10.1177/0192623391019004-110 Adler, K. B., & Henke, D. C. (1991). Effects of inflammatory mediators on epithelial function and integrity. In Lung biology in health and disease. (pp. 377–402). Adler, K. B., Kinnula, V., Akley, N. J., Lee, J., & Crapo, J. D. (1991). Effects of inflammatory mediators on generation and release of reactive oxygen species by airway epithelium in vitro. Proceedings of the 34th Aspen Lung Conference., Vol. 34, p. 33. COHN, L. A., & ADLER, K. B. (1991). INVITRO STUDIES OF MECHANISMS OF LUNG INJURY IN THE RODENT. TOXICOLOGIC PATHOLOGY, Vol. 19, pp. 419–427. https://doi.org/10.1177/0192623391019004-111 Adler, K. B., & Cohn, L. A. (1991). In vitro studies on mechanisms of lung injury in the rodent. Proceedings of the 10th International Symposium of Society of Toxicological Pathologists, Vol. 10. Lee, J., Akley, N. J., & Adler, K. B. (1991). Methods to study interactions between inhaled substances and epithelium of the respiratory tract in vitro. In Microbeam analysis- 1990. (pp. 457–458). Kaartinen, L., Nettesheim, P., Adler, K. B., & Randell, S. H. (1991). Modulation of rat tracheal epithelial cell differentiation in culture. American Review of Respiratory Disease, Vol. 143, p. A146. Glasgow, W., Akley, N. J., & Adler, K. B. (1991). Platelet activating factor provokes release of mucin like glycoproteins from guinea pig tracheal epithelial cells via a lipoxygenase-dependent mechanism. American Review of Respiratory Disease, Vol. 143, p. A147. Sannes, P., Peters, B., & Adler, K. (1991). Specific interactions with extracellular matrix may influence epithelial repair mechanisms in the pulmonary alveolus. Chest, 99, 70S–71. Low, R. B., Leslie, K. O., Hemenway, D. R., Absher, P. M., Alder, K. B., Giancola, M. S., & Vacek, P. M. (1990). Alveolar Type II cell response in rats exposed to aerosols of alpha cristobalite. American Journal of Pathology, 136, 923–931. ADLER, K. B., CHENG, P. W., & KIM, K. C. (1990). CHARACTERIZATION OF GUINEA-PIG TRACHEAL EPITHELIAL-CELLS MAINTAINED IN BIPHASIC ORGANOTYPIC CULTURE - CELLULAR COMPOSITION AND BIOCHEMICAL-ANALYSIS OF RELEASED GLYCOCONJUGATES. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2(2), 145–154. https://doi.org/10.1165/ajrcmb/2.2.145 Adler, K. B., Low, R. B., Leslie, K. O., Mitchell, J., & Evans, J. N. (1990). Contractile cells in normal and fibrotic lungs. In Pathology reviews. (pp. 25–37). https://doi.org/10.1007/978-1-4612-0485-5_3 MOSSMAN, B. T., MARSH, J. P., SESKO, A., HILL, S., SHATOS, M. A., DOHERTY, J., … KAGAN, E. (1990). INHIBITION OF LUNG INJURY, INFLAMMATION, AND INTERSTITIAL PULMONARY FIBROSIS BY POLYETHYLENE GLYCOL-CONJUGATED CATALASE IN A RAPID INHALATION MODEL OF ASBESTOSIS. AMERICAN REVIEW OF RESPIRATORY DISEASE, 141(5), 1266–1271. https://doi.org/10.1164/ajrccm/141.5_Pt_1.1266 Adler, K. B., Peters, B. P., Krunkosky, T., & Sannes, P. L. (1990). Interactions between extracellular matrix, airway and alveolar epithelium: alterations in fibrosis and possible pathogenetic significance. Proceedings of the Sixth International Colloquium Pulmonary Fibrosis., Vol. 6, p. 39. ADLER, K. B., HOLDENSTAUFFER, W. J., & REPINE, J. E. (1990). OXYGEN METABOLITES STIMULATE RELEASE OF HIGH-MOLECULAR-WEIGHT GLYCOCONJUGATES BY CELL AND ORGAN-CULTURES OF RODENT RESPIRATORY EPITHELIUM VIA AN ARACHIDONIC ACID-DEPENDENT MECHANISM. JOURNAL OF CLINICAL INVESTIGATION, 85(1), 75–85. https://doi.org/10.1172/jci114436 Adler, K. B., Akley, N. J., & Lee, J. (1990). Oxygen metabolites stimulate inositol lipid turnover in guinea pig airway epithelial cells in organotypic culture. American Review of Respiratory Disease, Vol. 141, p. A107. Sannes, P., Peters, B., & Adler, K. (1990). Specific interactions with extracellular matrix may influence epithelial repair mechanisms in the pulmonary alveolus. Proceedings of the 30th Aspen Lung Conference., Vol. 30, p. 24. Adler, K. B., Akley, N. J., Ayers, G., Holden-Stauffer, W. J., Khosla, J. B., & Kim, K. C. (1989). A novel culture system for maintaining differentiated epithelial cells between air and liquid phases: A possible model for studying interactions between mineral fibers, gases and airway epithelium. In Biological interaction of inhaled mineral fibers and cigarette smoke (pp. 381–390). Mitchell, J., Woodcock-Mitchell, J., Reynolds, S., Low, R., Leslie, K., Adler, K. B., … Skalli, O. (1989). Alpha smooth muscle actin in parenchymal cells of bleomycin injured rat lung. Laboratory Investigation, 60, 643–650. Adler, K. B., Low, R. B., Leslie, K. O., Mitchell, J., & Evans, J. N. (1989). Biology of disease: Contractile cells in normal and fibrotic lungs. Laboratory Investigation, 60, 473–485. Adler, K. B., Akley, N. J., & Holden-Stauffer, W. J. (1989). Oxidant injury to rodent airway epithelium in primary culture stimulates intracellular production of oxygen free radicals, arachidonic acid metabolism, and mucin secretion. American Review of Respiratory Disease, Vol. 139, p. A403. Whitcutt, J. M., Adler, K. B., & Wu, R. (1988). A biphasic chamber system for maintaining polarity of differentiation of cultured respiratory tract epithelial cells. In Vitro Cellular & Developmental Biology. Animal, 24, 420–428. https://doi.org/10.1007/bf02628493 Adler, K. B., & Kim, K. C. (1988). A new culture system for maintaining differentiated rodent respiratory epithelial cells between air and liquid phases: an excellent model for studying interactions between mineral fibers and airway epithelium in vitro. Proceedings of the Fourth International Workshop on Effects on Cells (Quebec, 1988), Vol. 4, p. 10. Coflesky, J. T., Adler, K. B., & Evans, J. N. (1988). Alterations in pulmonary vascular responsiveness following hyperoxic injury to the lung. Chest, 93, 147S–149. Coflesky, J. T., Adler, K. B., Woodcock-Mitchell, J., Mitchell, J., & Evans, J. N. (1988). An autoradiographic and biochemical analysis of cellular proliferation in pulmonary arteries following in vivo hyperoxia. American Review of Respiratory Disease, Vol. 137, p. 388. LOW, R. B., ADLER, K. B., WOODCOCKMITCHELL, J., GIANCOLA, M. S., & VACEK, P. M. (1988). BRONCHOALVEOLAR LAVAGE LIPIDS DURING DEVELOPMENT OF BLEOMYCIN-INDUCED FIBROSIS IN RATS - RELATIONSHIP TO ALTERED EPITHELIAL-CELL MORPHOLOGY. AMERICAN REVIEW OF RESPIRATORY DISEASE, 138(3), 709–713. https://doi.org/10.1164/ajrccm/138.3.709 Adler, K. B., & Holden-Stauffer, W. J. (1988). Exposure of rodent airway epithelium in vitro to oxidants stimulates cyclooxygenase metabolism of arachidonic acid. Proceedings of the 5th International Colloquium on Pulmonary Fibrosis (Lyon, France, 1988), Vol. 5, p. 5. Adler, K. B., Khosla, J., & Kim, K. C. (1988). Morphometric and biochemical characterization of a chamber system for maintaining differentiated guinea pig respiratory mucosal cells between air and liquid phases. American Review of Respiratory Disease, Vol. 137, p. 14. Adler, K. B., Akley, N. J., & Holden-Stauffer, W. J. (1988). Oxidant injury to airway epithelium in vitro stimulates cyclooxygenase metabolism of arachidonic acid and secretion of mucin. Journal of Cell Biology, Vol. 107, p. 350a. Adler, K. B., & Akley, N. J. (1988). Oxygen radicals stimulate secretion of mucin by rodent airway epithelial cells in organotypic culture. In Oxy radicals in molecular biology and pathology (pp. 101–108). Adler, K. B. (1988). Oxygen radicals stimulate secretion of mucin by rodent airway epithelial cells in organotypic culture. Journal of Cellular Biochemistry, Vol. 12A, p. 47. Coflesky, J. M., Adler, K. B., Woodcock Mitchell, J., Mitchell, J., & Evans, J. N. (1988). Proliferative changes in the pulmonary arterial wall during short term hyperoxic injury to the lung. American Journal of Pathology, 132, 563–573. Brody, A. R., Bitterman, P. B., Adler, K. B., Rannels, D. E., Thet L. A., R. W. N., & I., R. S. (1988). The lung matrix and inflammation: Part II. Biochemical and molecular mechanisms of fibrogenesis: implications for environmental lung disease. American Review of Respiratory Disease, 138, 1056–1057. Adler, K. B., Schwarz, J. E., Whitcutt, J. M., & Wu, R. (1987). A new chamber system for maintaining differentiated guinea pig respiratory epithelial cells between air and liquid phases. Biotechniques, 5, 462–467. Leslie, K. O., Woodcock-Mitchell, J., Mitchell, J., Adler, K., Low, R., Skalli, O., & Gabbiani, G. (1987). Alpha smooth muscle actin distribution in developing and adult lung. Journal of Cell Biology, Vol. 105, p. 25a. Coflesky, J. T., Adler, K. B., & Evans, J. N. (1987). Alterations in pulmonary vascular responsiveness following hyperoxic injury to the lung. Proceedings of the 27th Aspen Lung Conference., p. 18. Mossman, B. T., Marsh, J. P., Gilbert R., H., D. H., S., A., W., A., H., … Kagan, E. (1987). Dosage dependent inhibition of lung injury, inflammation and fibrosis by polyethylene glycol (PEG)-conjugated catalase in rats exposed by inhalation to asbestos. American Review of Respiratory Disease, Vol. 135, p. A165. Butler, G. B., Adler, K. B., Evans, J. N., & Szarek, J. (1987). Modulation of rabbit airway smooth muscle responsiveness by respiratory epithelium: involvement of an inhibitory metabolite of arachidonic acid. American Review of Respiratory Disease, 135, 1099–1104. ADLER, K. B., SCHWARZ, J. E., ANDERSON, W. H., & WELTON, A. F. (1987). PLATELET-ACTIVATING-FACTOR STIMULATES SECRETION OF MUCIN BY EXPLANTS OF RODENT AIRWAYS IN ORGAN-CULTURE. EXPERIMENTAL LUNG RESEARCH, 13(1), 25–43. https://doi.org/10.3109/01902148709064307 Adler, K. B., & Repine, J. R. (1987). Superoxide anion stimulates arachidonic acid dependent secretion of mucin by explant and cell cultures of rodent respiratory epithelium. American Review of Respiratory Disease, Vol. 135, p. A164. Szarek, J. L., Buter, G. B., Adler, K. B., & Evans, J. N. (1986). A cyclooxygenase product of arachidonic acid is involved in epithelium mediated modulation of rabbit airway smooth muscle responsiveness. American Review of Respiratory Disease, Vol. 133, p. A115. Adler, K. B., Whitcutt, J. M., & Wu, R. (1986). A new chamber system for maintaining differentiated guinea pig respiratory epithelial cells between air and liquid phases. Journal of Cell Biology, Vol. 103, p. 207a. Adler, K. B., Callahan, L. M., & Evans, J. N. (1986). Alterations in the cellular population of the alveolar wall in bleomycin induced pulmonary fibrosis in rats: an ultrastructural morphometric study. American Review of Respiratory Disease, 133, 1043–1048. Callahan, L. M., Evans, J. N., & Adler, K. B. (1986). Alterations in the cellular population of the alveolar wall in an animal model of fibrosis: a morphometric study. Chest, 89, 189S–190. Adler, K. B., Hendley, D. D., & Davis, G. S. (1986). Bacteria associated with chronic obstructive pulmonary disease elaborate extracellular products that stimulate secretion of mucin by explants of guinea pig airways. American Journal of Pathology, 125, 501–514. Coflesky, J. T., Adler, K. B., Anderson, W. H., & Evans, J. N. (1986). Effects of hyperoxia on metabolism of arachidonic acid by pulmonary vessels and airways. In Vitro Cellular & Developmental Biology. Animal, Vol. 22, p. 44A. Brody, A. R., Hill, L. H., Hesterberg, T. W., Barrett, J. C., & Adler, K. B. (1986). Intracellular translocation of inorganic particles. In The cytoskeleton. (pp. 221–227). https://doi.org/10.1007/978-1-4613-2161-3_17 Mossman, B. T., & Adler, K. B. (1986). Mechanisms of asbestos induced toxicity and lung disease. In Vitro Cellular & Developmental Biology. Animal, Vol. 22, p. 49A. Adler, K. B. (1986). Mucin secretion by respiratory tract tissue in vitro. In In vitro models of respiratory epithelium (pp. 27–50). Adler, K. B., Schwarz, J. E., & Repine, J. E. (1986). Oxygen free radicals stimulate secretion of mucin by rodent respiratory epithelium in vitro. In Microbeam analysis -- 1986. (pp. 571–573). Adler, K. B., Schwarz, J. E., Anderson, W. H., & Welton, A. F. (1986). Platelet activating factor stimulates secretion of mucin by explants of rodent airways in organ culture. American Review of Respiratory Disease, Vol. 133, p. A212. Adler, K. B., Callahan, L. M., & Evans, J. N. (1985). Alterations in the cellular population of the alveolar wall in an animal model of fibrosis: a morphometric study. Proceedings of the Aspen Lung Conference., p. 24. Adler, K. B., Schwartz, J. E., & Butler, G. B. (1985). Effects of arachidonate metabolites on mucin secretion by explants of rabbit bile and pancreatic ducts in organ culture. 404nOtfound, Vol. 26, p. 47. Adler, K. B., Butler, G. B., Hemenway, D. R., Schwarz, J. E., Banks, P. O., & Evans, J. N. (1985). Exposure of small airways to cristobalite in vitro. In In vitro effects of mineral dusts.: Vol. G-3 (pp. 293–301). Shatos, M. A., Adler, K. B., Doherty, J. M., Orfeo, T., & Mossman, B. T. (1985). Localization of intracellular and extracellular SOD in cells of the lung: increased enzyme activity after exposure to asbestos. American Review of Respiratory Disease, Vol. 131, p. A187. Butler, G. B., Adler, K. B., Evans, J. N., & Szarek, J. L. (1985). Modulation of rabbit airway smooth muscle tone by the respiratory epithelium is mediated by a dilatory prostaglandin. 404nOtfound, Vol. 27, p. 187. Adler, K. B., Callahan, L. M., & Evans, J. N. (1985). Quantitative measure of cellular changes in pulmonary parenchyma of rats with bleomycin induced fibrosis. American Review of Respiratory Disease, Vol. 131, p. A32. Adler, K. B., Schwarz, J. E., & Repine, J. E. (1985). Superoxide, but not peroxide, stimulates secretion of mucin by explants of rodent airway tissue in organ culture. Journal of Cell Biology, Vol. 101, p. 104a. Low, R. B., Mitchell, J. W., Evans, J. N., & Adler, K. B. (1984). Actin content in normal and bleomycin fibrotic rat lung. American Review of Respiratory Disease, 129, 311–316. Adler, K. B., Butler, G. B., & Welton, A. F. (1984). Cyclooxygenase and lipoxygenase metabolites of arachidonic acid influence mucin secretion by explants of rodent airways. Journal of Cell Biology, Vol. 99, p. 929. Adler, K. B., Hendley, D. D., Schwarz, J. E., & Davis, G. S. (1984). Exoproducts from bacteria associated with chronic bronchitis stimulate secretion of mucin by rodent tracheal explants in organ culture. American Review of Respiratory Disease, Vol. 129, p. A182. ADLER, K. B., MOSSMAN, B. T., BUTLER, G. B., JEAN, L. M., & CRAIGHEAD, J. E. (1984). INTERACTION OF MOUNT ST-HELENS VOLCANIC ASH WITH CELLS OF THE RESPIRATORY EPITHELIUM. ENVIRONMENTAL RESEARCH, 35(2), 346–361. https://doi.org/10.1016/0013-9351(84)90142-7 Woodcock-Mitchell, J., Adler, K. B., & Low, R. B. (1984). Immunohistochemical identification of cell types in normal and in bleomycin induced fibrotic rat lung. American Review of Respiratory Disease, 130, 910–916. Adler, K. B., Butler, G. B., & Evans, J. N. (1984). Involvement of prostaglandins in both mucin secretion and contractility of rabbit pancreatic and bile ducts in vitro. 404nOtfound, Vol. 25, p. 195. Adler, K. B., & Hendley, D. D. (1984). Stimulation of airway mucin secretion by an exoproduct elaborated by Pseudomonas aeruginosa: preliminary isolation. 404nOtfound, Vol. 25, p. 121. Brody, A. R., Hill, L., Stirewalt, W., & Adler, K. B. (1983). Actin containing microfilaments of pulmonary epithelial cells provide a mechanism for translocating inhaled asbestos to the interstitium. Chest, 83, 11S–13. Evans, J. N., Krill, J., Adler, K. B., Low, R. B., & Kelley, J. (1983). Active cellular control of alveolar compliance. Current Problems in Clinical Biochemistry, 13, 142–148. Craighead, J. E., Adler, K. B., Butler, G. B., Emerson, R. J., Mossman, B. T., & Woodworth, C. W. (1983). Biology of disease: health effects of Mount St. Helens volcanic dust. Laboratory Investigation, 48, 5–12. Adler, K. B., & Butler, G. B. (1983). Cellular mechanisms of mucin secretion by rodent epithelial cells in vitro. Journal of Cell Biology, Vol. 97, p. 437a. Low, R. B., Mitchell, J. W., Evans, J. N., & Adler, K. B. (1983). Contractile proteins of the lung. Current Problems in Clinical Biochemistry, 13, 149–156. ADLER, K. B., KRILL, J., ALBERGHINI, T. V., & EVANS, J. N. (1983). EFFECT OF CYTOCHALASIN-D ON SMOOTH-MUSCLE CONTRACTION. CELL MOTILITY AND THE CYTOSKELETON, 3(5-6), 545–551. https://doi.org/10.1002/cm.970030521 Adler, K. B., Krill, J., Alberghini, T., & Evans, J. N. (1983). Effects of cytochalasin D on contraction of isolated pulmonary vessels. Proceedings of the 2nd International Conference on Cell Biol Struct., Vol. 2, p. 15. Woodcock-Mitchell, J., Adler, K. B., & Low, R. B. (1983). Immunohistochemical studies of cell types in normal and fibrotic rat lung. American Review of Respiratory Disease, Vol. 127, p. 68. ADLER, K. B., ALBERGHINI, T. V., COUNTS, D. F., & AULETTA, F. J. (1983). SECRETION OF MUCIN BY EXPLANTS OF RABBIT AND HUMAN CERVIX IN ORGAN-CULTURE. BIOLOGY OF REPRODUCTION, 29(3), 751–765. https://doi.org/10.1095/biolreprod29.3.751 Adler, K. B., Winn, W. C., Jr., Alberghini, T. V., & Craighead, J. E. (1983). Stimulatory effect of Pseudomonas aeruginosa on mucin secretion by respiratory epithelium. 404nOtfound, 249, 1615–1617. Evans, J. N., Low, R. B., Kelley, J. K., J., & Adler, K. B. (1983). The myofibroblast in pulmonary fibrosis. Chest, 83, 97S–99. ADLER, K. B., WINN, W. C., HARDWICK, D. H., & CRAIGHEAD, J. E. (1982). EFFECTS OF BACTERIAL PRODUCTS ON SECRETION OF MUCIN BY RODENT TRACHEA INVITRO. CHEST, 81(5), S37–S39. https://doi.org/10.1378/chest.81.5_supplement.37s Low, R. B., Evans, J. N., & Adler, K. B. (1982). Effects of bleomycin induced pulmonary fibrosis on lung actin content and polymerization. American Review of Respiratory Disease, Vol. 125, p. 218. Evans, J. N., Kelley, J., Low, R. B., & Adler, K. B. (1982). Increased contractility of isolated lung parenchyma in an animal model of pulmonary fibrosis induced by bleomycin. American Review of Respiratory Disease, 125, 89–94. Mossman, B. T., Adler, K. B., Jean, L., & Craighead, J. E. (1982). Mechanisms of hypersecretion in rodent tracheal explants after exposure to chrysotile asbestos: studies using lectins. Chest, 91, 23S–25. ADLER, K. B., HARDWICK, D. H., & CRAIGHEAD, J. E. (1982). PORCINE TRACHEAL GOBLET CELL ULTRASTRUCTURE - A 3-DIMENSIONAL RECONSTRUCTION. EXPERIMENTAL LUNG RESEARCH, 3(1), 69–80. https://doi.org/10.3109/01902148209115817 Adler, K. B., Craighead, J. E., Vallyathan, N. V., & Evans, J. N. (1981). Actin containing cells in human pulmonary fibrosis. American Journal of Pathology, 102, 427–438. Emerson, R. J., Adler, K. B., Evans, J. N., & Davis, G. S. (1981). Alveolar macrophage heterogeneity in silica exposed rats. American Review of Respiratory Disease, Vol. 123, p. 138. Adler, K. B., Hardwick, D. H., & Craighead, J. E. (1981). Effect of cholera toxin on secretion of mucin by explants of guinea pig trachea. Laboratory Investigation, 45, 372–377. Adler, K. B., Winn, W. C., & Craighead, J. E. (1981). Effects of bacterial products on secretion of mucin by rodent trachea in vitro. Proceedings of the 24th Aspen Lung Conference., Vol. 24, p. 21. Mossman, B. T., Adler, K. B., & Craighead, J. (1981). Mechanisms of hypersecretion in rodent tracheal explants after exposure to chrysotile asbestos. Proceedings of the 24th Aspen Lung Conference., Vol. 24, p. 13. Adler, K. B., St. Andre-Ukena, S., & Beeken, W. (1981). Preliminary characterization of macrophages isolated from the human colon. Gastroenterology, Vol. 80, p. 1097. Adler, K. B., Winn, W. C., Jr., Hardwick, D. H., & Craighead, J. E. (1981). Stimulation by bacterial products of mucin secretion in rodent tracheal explants. 404nOtfound, Vol. 22, p. 91. Adler, K. B., Brody, A. R., & Craighead, J. E. (1981). Studies on the mechanism of mucin secretion by cells of the porcine tracheal epithelium. Proceedings of the Society for Experimental Biology and Medicine, 166, 96–106. https://doi.org/10.3181/00379727-166-41030 Evans, J. N., & Adler, K. B. (1981). The lung strip: evaluation of a method to study contractility of pulmonary parenchyma. Experimental Lung Research, 2, 187–194. https://doi.org/10.3109/01902148109052314 Adler, K. B., & Craighead, J. E. (1980). Cellular mechanisms of respiratory tract mucin secretion. Proceedings of the 8th International Congress on Cystic Fibrosis., Vol. 8, p. 1a. Davis, G. S., Brody, A. R., & Adler, K. B. (1980). Changes in the surface morphology of human alveolar macrophages induced by tobacco and marijuana smoking. Chest, 1, 281–293. Mossman, B. T., Adler, K. B., & Craighead, J. E. (1980). Cytotoxic and proliferative changes in tracheal organ and cell cultures after exposure to mineral dusts. In The in vitro effects of mineral dusts (pp. 241–250). Mossman, B. T., Ezerman, E. B., Adler, K. B., & Craighead, J. E. (1980). Isolation and spontaneous transformation of cloned lines of hamster tracheal epithelial cells. Cancer Research, 40, 4403–4408. Davis, G. S., & Adler, K. B. (1980). Morphologic changes induced in human alveolar macrophages by levamisole treatment. American Review of Respiratory Disease, Vol. 121, p. 64. Adler, K. B., Kelley, J., & Evans, J. N. (1980). Morphological and pharmacological evidence of increased contractility in human and rat fibrotic lungs. American Review of Respiratory Disease, Vol. 121, p. 309. Adler, K. B., Hardwick, D. H., & Craighead, J. E. (1980). Stimulatory effects of cholera toxin on secretion of mucin by tracheal explants in organ culture. Journal of Cell Biology, Vol. 87, p. 307a. Davis, G. S., Adler, K. B., & Brody, A. R. (1980). The morphology of alveolar macrophage immunologic activation: a scanning electron microscopic study. American Review of Respiratory Disease, Vol. 121, p. 269. Kelley, J., Adler, K. B., & Davis, G. S. (1979). Alveolar macrophage function in desquamative interstitial pneumonitis. 404nOtfound, Vol. 27, p. 569A. Davis, G. S., Brody, A. R., & Adler, K. B. (1979). Functional and physiological correlates of human alveolar macrophage cell shape and surface morphology. Chest, 75S, 280–282. https://doi.org/10.1016/s0012-3692(15)30441-4 Adler, K. B., Hardwick, D. H., & Craighead, J. E. (1979). Mechanisms of mucin secretion by porcine tracheal goblet cells. American Review of Respiratory Disease, Vol. 119, p. 285. Adler, K. B., Vallyathan, N. V., Kelley, J., & Evans, J. N. (1979). Nonmuscle contractile cells in pulmonary fibrosis. Journal of Cell Biology, Vol. 83, p. 319a. Adler, K. B., Davis, G. S., Woodworth, C. W., & Brody, A. R. (1979). The human pulmonary alveolar macrophage: two distinct morphological populations. Scanning Electron Microscopy, 3, 921–928. Adler, K. B., Brody, A. R., & Craighead, J. E. (1978). Association of microtubules and microfilaments with mucin granules in tracheal goblet cells their possible role in exocytosis. Proceedings of the 9th International Congress on Electron Microscopy, 2, 500–501. Evans, J. N., Previti, R. A., Adler, K. B., & Vallyathan, N. V. (1978). Contractile properties of peripheral lung tissue. 404nOtfound, Vol. 21, p. 35. MOSSMAN, B. T., ADLER, K. B., & CRAIGHEAD, J. E. (1978). INTERACTION OF CARBON PARTICLES WITH TRACHEAL EPITHELIUM IN ORGAN-CULTURE. ENVIRONMENTAL RESEARCH, 16(1-3), 110–122. https://doi.org/10.1016/0013-9351(78)90148-2 Adler, K. B., Brody, A. R., & Davis, G. S. (1978). Localization of actin in surface ruffles of pulmonary alveolar macrophages: Effects of cytochalasin B, colchicine and cyclic AMP. Journal of Cell Biology, Vol. 79, p. 276a. Adler, K. B., Brody, A. R., & Craighead, J. E. (1978). Ultrastructural association of microtubules and microfilaments with mucin granules in porcine tracheobronchial tissue in organ culture. 404nOtfound, Vol. 37, p. 266. Adler, K. B., Mossman, B. T., & Craighead, J. E. (1977). Interaction of carbon particles with rodent tracheal epithelium in organ culture. In Vitro Cellular & Developmental Biology. Animal, Vol. 13, p. 202. Adler, K. B., & Fand, I. (1977). The cilioinhibitory effect of phenothiazine in vitro and its antagonism by calcium. Archives Internationales De Pharmacodynamie Et De Therapie, 227, 309–322. Ezerman, E. B., Adler, K. B., & Craighead, J. E. (1976). Isolation of epithelial cells from hamster tracheal respiratory epithelium. In Vitro Cellular & Developmental Biology. Animal, Vol. 12, p. 319. Adler, K. B., & Dulfano, M. J. (1976). The rheological factor in mucociliary clearance. Journal of Laboratory and Clinical Medicine, 88, 22–30. Dulfano, M. J., & Adler, K. B. (1975). Physical properties of sputum. VII. Rheologic properties and mucociliary transport. American Review of Respiratory Disease, 112, 341–348. Fand, I., & Adler, K. B. (1974). Cilioinhibitory effect of chlorpromazine in vitro and its antagonism by calcium. In Vitro Cellular & Developmental Biology. Animal, Vol. 10, p. 341. Dulfano, M. J., & Adler, K. B. (1974). Mucociliary clearance and mucus viscoelasticity. Chest, Vol. 66, p. 323. Adler, K. B., Dulfano, M. J., & Wooten, O. (1974). Physical properties of sputum. V. The effects of time, freezing and thawing on viscoelasticity measurements. American Review of Respiratory Disease, 109, 490–492. ADLER, K. B., WOOTEN, O., & DULFANO, M. J. (1973). MAMMALIAN RESPIRATORY MUCOCILIARY CLEARANCE. ARCHIVES OF ENVIRONMENTAL HEALTH, 27(6), 364–369. https://doi.org/10.1080/00039896.1973.10666403 Dulfano, M. J., Adler, K. B., & Wooten, O. (1973). Physical properties of sputum. IV. The effects of 100% humidity and water mist. American Review of Respiratory Disease, 107, 130–133. Adler. K. B., W., O., P., W., L., E., & Dulfano, M. J. (1972). Physical properties of sputum. III. Rheological variability and intrinsic relationships. American Review of Public Administration, 106, 86–96.