Kathryn Racine

Works (9)

Updated: October 31st, 2024 05:01

2024 journal article

The high-fat diet and low-dose streptozotocin type-2 diabetes model induces hyperinsulinemia and insulin resistance in male but not female C57BL/6J mice

Nutrition Research, 131, 135–146.

By: K. Racine n, L. Iglesias-Carres  n, J. Herring*, K. Wieland*, P. Ellsworth *, J. Tessem *, M. Ferruzzi*, C. Kay* , A. Neilson n 

author keywords: Diabetes; Insulin; Beta cells; Sexual dimorphism; High-fat diet
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: October 28, 2024

2023 journal article

Mechanism of off-color formation in potato chips fried in oil systems containing ascorbic acid as a stabilizer

LWT, 179, 114682.

By: L. Iglesias-Carres  n, K. Racine n, S. Chadwick n, C. Nunn  n, S. Kalambur*, A. Neilson n , M. Ferruzzi*

author keywords: Amino acid; Maillard reaction; BHT; Rosemary; Carnosic acid; Tocopherol; Moisture; Solubility; Citric acid; Canola oil
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: June 12, 2023

2022 journal article

Cocoa extract exerts sex-specific anti-diabetic effects in an aggressive type-2 diabetes model: A pilot study

Biochemical and Biophysical Research Communications, 626, 205–210.

By: K. Racine n, L. Iglesias-Carres  n, J. Herring *, M. Ferruzzi n, C. Kay n , J. Tessem *, A. Neilson n 

author keywords: BTBR; Ob/ob; Type-2 diabetes; Flavanol; Insulin; Beta cell
MeSH headings : Animals; Cacao; Diabetes Mellitus, Type 2 / drug therapy; Female; Humans; Hyperglycemia; Hyperinsulinism; Male; Mice; Obesity; Pilot Projects; Plant Extracts / pharmacology; Plant Extracts / therapeutic use
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: October 17, 2022

2022 journal article

Effect of processing on the anti-inflammatory efficacy of cocoa in a high fat diet-induced mouse model of obesity

The Journal of Nutritional Biochemistry, 109, 109117.

By: D. Weikart *, V. Indukuri*, K. Racine n, K. Coleman*, J. Kovac *, D. Cockburn *, H. Hopfer *, A. Neilson n , J. Lambert*

author keywords: Cocoa; sex differences; roasting; fermentation; obesity; inflammation
MeSH headings : Animals; Anti-Inflammatory Agents / pharmacology; Anti-Inflammatory Agents / therapeutic use; Body Weight; Cacao; Chocolate; Diet, High-Fat / adverse effects; Disease Models, Animal; Food Ingredients; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Polyphenols / pharmacology
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, NC State University Libraries
Added: October 11, 2022

2022 article

Phenolic-rich beverages reduce bacterial TMA formation in an ex vivo-in vitro colonic fermentation model

Iglesias-Carres, L., Racine, K. C., & Neilson, A. P. (2022, July 11). FOOD & FUNCTION, Vol. 7.

By: L. Iglesias-Carres  n, K. Racine n & A. Neilson n 

MeSH headings : Atherosclerosis / metabolism; Bacteria / metabolism; Beverages; Chlorogenic Acid; Choline / metabolism; Coffee; Fermentation; Humans; Methylamines / metabolism
TL;DR: Regular cocoa and coffee consumption could be a nutritional strategy able to reduce TMAO levels, and fractionating digested bioactive beverages determined that those fractions rich in chlorogenic acid were the most bioactive. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: July 26, 2022

2020 journal article

Diet-induced obesity in genetically diverse collaborative cross mouse founder strains reveals diverse phenotype response and amelioration by quercetin treatment in 129S1/SvImJ, PWK/EiJ, CAST/PhJ, and WSB/EiJ mice

The Journal of Nutritional Biochemistry, 87, 108521.

By: L. Griffin n, L. Essenmacher *, K. Racine n, L. Iglesias-Carres  n, J. Tessem *, S. Smith *, A. Neilson n 

author keywords: Natural products; Genetic diversity; Diabetes; Flavonoids; Personalized nutrition; Interindividual variation
MeSH headings : Animals; Anti-Obesity Agents / therapeutic use; Collaborative Cross Mice / genetics; Collaborative Cross Mice / physiology; Diet, High-Fat / adverse effects; Disease Models, Animal; Female; Genetic Variation; Male; Obesity / drug therapy; Obesity / etiology; Obesity / genetics; Quercetin / therapeutic use; Sex Factors
TL;DR: How diverse mouse strains respond to diet-induced obesity when fed a representative flavonoid is explored to justify use of genetically diverse Collaborative Cross and Diversity Outbred models which are emerging as invaluable tools in the field of personalized nutrition. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: January 11, 2021

2019 journal article

Development of a rapid ultra performance hydrophilic interaction liquid chromatography tandem mass spectrometry method for procyanidins with enhanced ionization efficiency

JOURNAL OF CHROMATOGRAPHY A, 1594, 54–64.

By: K. Racine*, A. Lee *, A. Stewart *, K. Blakeslee* & A. Neilson n 

author keywords: Cocoa; Sensitivity; Electrospray ionization; Diol; Ammonium formate
MeSH headings : Biflavonoids / analysis; Biflavonoids / isolation & purification; Catechin / analysis; Catechin / isolation & purification; Chemistry Techniques, Analytical / methods; Chromatography, Liquid; Formates / chemistry; Hydrophobic and Hydrophilic Interactions; Limit of Detection; Proanthocyanidins / analysis; Proanthocyanidins / isolation & purification; Tandem Mass Spectrometry
TL;DR: This method builds upon the foundation set by existing analytical methods and employs new technologies to dramatically increase sample throughput and enhance detection limits and specificity, facilitating improved analysis for procyanidins. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: May 28, 2019

2019 journal article

Flavanol Polymerization Is a Superior Predictor of α-Glucosidase Inhibitory Activity Compared to Flavanol or Total Polyphenol Concentrations in Cocoas Prepared by Variations in Controlled Fermentation and Roasting of the Same Raw Cocoa Beans

Antioxidants, 8(12), 635.

By: K. Racine*, B. Wiersema *, L. Griffin n, L. Essenmacher *, A. Lee *, H. Hopfer *, J. Lambert *, A. Stewart *, A. Neilson n 

author keywords: flavan-3-ol; procyanidin; alpha-glucosidase; melanoidin; Maillard reaction
TL;DR: It is demonstrated that cocoa powders are potent inhibitors of α-glucosidase, and non-traditional compositional markers may be better predictors of enzyme inhibitory activity than cocoa native flavanols. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: January 27, 2020

2019 journal article

Flavanol supplementation protects against obesity-associated increases in systemic interleukin-6 levels without inhibiting body mass gain in mice fed a high-fat diet

Nutrition Research, 66, 32–47.

By: L. Griffin*, D. Fausnacht *, J. Tuzo*, A. Addington *, K. Racine*, H. Zhang*, M. Hughes *, K. England* ...

author keywords: Mean degree of polymerization (mDP); Flavanols; Procyanidins (PCs); Glucose intolerance; Cytokines
MeSH headings : Adipose Tissue / chemistry; Animals; Body Composition / drug effects; Diet, High-Fat / adverse effects; Dietary Supplements; Eating / drug effects; Flavonols / administration & dosage; Glucose Intolerance / prevention & control; Grape Seed Extract / chemistry; Inflammation / prevention & control; Insulin Resistance; Interleukin-6 / analysis; Male; Mice; Mice, Inbred C57BL; Obesity / physiopathology; Pinus / chemistry; Plant Bark / chemistry; Weight Gain / drug effects
TL;DR: Overall, low-dose flavanol extract supplementation, regardless of mean degrees of polymerization, blunted cytokine production despite increased weight gain, suggesting flavanols may be used as complementary interventions to ameliorate increased inflammatory tone in the contexts of obesity and diabetes. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: July 22, 2019

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2025) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.