Katarzyna Dembek

Works (13)

Updated: April 5th, 2024 13:16

2023 article

Assessment of the hypothalamic-pituitary-adrenocortical axis function using a vasopressin stimulation test in neonatal foals

Elder, E., Wong, D., Johnson, K., Robertson, H., Marner, M., & Dembek, K. (2023, July 11). JOURNAL OF VETERINARY INTERNAL MEDICINE.

By: E. Elder n, D. Wong *, K. Johnson *, H. Robertson n, M. Marner* & K. Dembek n

author keywords: adrenal insufficiency; equine; equine neonates; sepsis
TL;DR: A stimulation test with AVP (5 IU) can be considered for HPAA assessment in septic foals and results in a significant rise in ACTH and cortisol in neonatal foals. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: July 24, 2023

2023 journal article

General anesthesia does not induce ultrasonographic changes in the pleura of healthy adult horses anesthetized for elective magnetic resonance imaging

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 261(4), 500–504.

By: K. Hepworth-Warren, N. Nelson, K. Dembek & K. Young

UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: May 9, 2023

2023 journal article

Longitudinal assessment of adrenocortical steroid and steroid precursor response to illness in hospitalized foals

DOMESTIC ANIMAL ENDOCRINOLOGY, 82.

By: K. Dembek n, K. Timko *, C. Moore, L. Johnson*, M. Frazer*, B. Barr*, R. Toribio *

author keywords: Sepsis; Equine neonates; Neurosteroids; Hypothalamic -pituitary -adrenal axis; Relative adrenal insufficiency
MeSH headings : Horses; Animals; Hydrocortisone; Adrenocorticotropic Hormone; Critical Illness; Animals, Newborn; Horse Diseases; Progesterone; Aldosterone; Progestins; Steroids; Sepsis / veterinary; Hospitalization
TL;DR: Critically ill neonatal foals had an appropriate response to stress characterized by increased concentrations of cortisol and steroid precursors on admission, and persistently elevated progestogen and androgen concentrations were associated with a lack of improvement in the course of disease and poor outcome. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: October 17, 2022

2023 article

Longitudinal effects of oral administration of antimicrobial drugs on fecal microbiota of horses

Gomez, D., Toribio, R., Caddey, B., Costa, M., Vijan, S., & Dembek, K. (2023, September 8). JOURNAL OF VETERINARY INTERNAL MEDICINE.

By: D. Gomez *, R. Toribio *, B. Caddey*, M. Costa *, S. Vijan* & K. Dembek n

author keywords: antimicrobial-associated diarrhea; colitis; dysbiosis; gastrointestinal; macrolides
TL;DR: Oral administration of antimicrobials alters the intestinal microbiota of healthy horses resembling horses with dysbiosis, potentially resulting in intestinal inflammation and predisposition to diarrhea. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: October 2, 2023

2023 article

The hypothalamic-pituitary-adrenal axis response to ovine corticotropin-releasing-hormone stimulation tests in healthy and hospitalized foals

Johnson, K., Peterson, J., Kopper, J., & Dembek, K. (2023, January 18). JOURNAL OF VETERINARY INTERNAL MEDICINE.

By: K. Johnson *, J. Peterson*, J. Kopper * & K. Dembek n

author keywords: adrenocorticotropic hormone; arginine vasopressin; cortisol; endocrine; sepsis
MeSH headings : Animals; Sheep; Horses; Adrenocorticotropic Hormone; Corticotropin-Releasing Hormone / pharmacology; Hydrocortisone; Hypothalamo-Hypophyseal System; Prospective Studies; Pituitary-Adrenal System
TL;DR: One microgram per kilogram of oCRH appears to be optimal for the assessment of HPAA in healthy and hospitalized foals, and cortisol, ACTH, and eCRH concentrations increased in response to administration of all doses of o CRH. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: February 6, 2023

2022 journal article

Comparison of Fluid Analysis and Cytologic Findings of Cerebrospinal Fluid Between Three Collection Sites in Adult Equids With Neurological Disease

FRONTIERS IN VETERINARY SCIENCE, 9.

By: K. Young n, K. Hepworth-Warren  n & K. Dembek n

author keywords: equine protozoal myeloencephalitis (EPM); cytopathology; atlanto-occipital; atlantoaxial; lumbosacral
TL;DR: There were minimal differences in multiple other parameters between sites, which are likely clinically insignificant and have clinical implications due to the importance of comparative diagnostics and its potential impact on cytologic evaluation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: May 23, 2022

2022 journal article

Comparison of thoracic ultrasonography and thoracic radiography between healthy adult horses and horses with bacterial pneumonia using a novel, objective ultrasonographic scoring system

FRONTIERS IN VETERINARY SCIENCE, 9.

By: K. Hepworth-Warren  n, N. Nelson n, K. Dembek n & K. Young n

author keywords: equine pneumonia; thoracic radiography; imaging; equine pleuropneumonia; ultrasonography
TL;DR: TUS appears to be an acceptable stand-alone imaging modality for diagnosis of bacterial pneumonia in horses when radiography is not practical and to validate a novel, objective scoring system for TUS in adult horses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 7, 2022

2022 journal article

Comparison of two glucose-monitoring systems for use in horses

AMERICAN JOURNAL OF VETERINARY RESEARCH, 83(3), 222–228.

By: C. Malik*, D. Wong *, K. Dembek n & K. Wilson *

MeSH headings : Animals; Blood Glucose; Blood Glucose Self-Monitoring / veterinary; Electrocardiography; Horses; Monitoring, Physiologic / methods; Monitoring, Physiologic / veterinary; Point-of-Care Systems
TL;DR: Data from this study support the use of the Dexcom G6 and Freestyle Libre 14-day interstitial glucose-monitoring systems to estimate blood glucose concentrations in horses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: March 7, 2022

2022 article

The fecal bacterial microbiota of healthy and sick newborn foals

Gomez, D. E., Wong, D., MacNicol, J., & Dembek, K. (2022, December 14). JOURNAL OF VETERINARY INTERNAL MEDICINE.

By: D. Gomez *, D. Wong *, J. MacNicol * & K. Dembek n

author keywords: Aerococcus; Enterobacteriaceae; Enterococcus; equine neonates; sepsis; Streptococcus
MeSH headings : Pregnancy; Female; Animals; Horses; Animals, Newborn; Case-Control Studies; Feces / microbiology; Microbiota; Bacteria / genetics; Horse Diseases; Bacteremia / veterinary
TL;DR: Higher fecal microbiota diversity in sick than healthy foals might suggest a high exposure to environmental microorganisms or an unstable colonic microbiota, and the intestine might play an essential role in the causation of bacteremia in foals. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: January 9, 2023

2021 article

Blood thiamine (vitamin B-1), ascorbic acid (vitamin C), and cortisol concentrations in healthy and ill neonatal foals

Wong, D. M., Young, L., & Dembek, K. A. (2021, May 30). JOURNAL OF VETERINARY INTERNAL MEDICINE.

By: D. Wong *, L. Young* & K. Dembek n

author keywords: hydrocortisone; hypovitaminosis; sepsis; treatment
MeSH headings : Animals; Animals, Newborn; Ascorbic Acid; Horse Diseases / drug therapy; Horses; Hydrocortisone; Prospective Studies; Sepsis / drug therapy; Sepsis / veterinary; Thiamine; Vitamins
TL;DR: A potential association exists between illness in foals and lower blood concentrations of thiamine and ascorbic acid during hospitalization, and a larger population of foals is needed to examine the clinical impact of low vitamin concentrations, if any, on morbidity and mortality. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: June 10, 2021

2021 journal article

Development of a Colic Scoring System to Predict Outcome in Horses

FRONTIERS IN VETERINARY SCIENCE, 8.

By: A. Farrell*, K. Kersh*, R. Liepman & K. Dembek n

author keywords: horse; colic; survival; prognosis; retrospective
TL;DR: A retrospective, multi-institutional clinical study was performed to determine clinical parameters associated with survival of horses with colic, and to use them to develop a colic survival scoring system that was validated using clinical data in the prospective portion of the study. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: November 15, 2021

2021 journal article

Dynamics of androgens in healthy and hospitalized newborn foals

JOURNAL OF VETERINARY INTERNAL MEDICINE, 35(1), 538–549.

By: J. Swink *, L. Rings*, H. Snyder*, R. McAuley*, T. Burns *, K. Dembek n, W. Gilsenan*, N. Browne*, R. Toribio *

author keywords: androgens; equine neonate; foal; progestogens; sepsis; sex steroids; steroidogenesis
MeSH headings : Androgens; Animals; Animals, Newborn; Cross-Sectional Studies; Horse Diseases; Horses; Prospective Studies; Sepsis / veterinary
TL;DR: Increased serum concentrations of androgens are associated with disease severity and adverse outcome in hospitalized newborn foals, similar to glucocorticoids, mineralocortICoids, and progestagens. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: December 21, 2020

2021 article

Evaluation of a continuous glucose monitoring system in neonatal foals

Wong, D., Malik, C., Dembek, K., Estell, K., Marchitello, M., & Wilson, K. (2021, June 6). JOURNAL OF VETERINARY INTERNAL MEDICINE.

By: D. Wong *, C. Malik*, K. Dembek n, K. Estell *, M. Marchitello* & K. Wilson*

author keywords: critical care; nutrition; point-of-care; sepsis
MeSH headings : Animals; Blood Glucose; Blood Glucose Self-Monitoring / veterinary; Glucose; Horses; Monitoring, Physiologic / veterinary; Point-of-Care Systems
TL;DR: Within the blood glucose concentration ranges in this study, CGMS measurements were significantly correlated with CHEM, suggesting that it is an acceptable method to provide meaningful, immediate, and continuous glucose concentration measurements in neonatal foals while eliminating the need for repeated restraint and blood collection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: June 14, 2021

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