Works (14)

Updated: September 11th, 2023 08:10

2023 journal article

An inhaled bioadhesive hydrogel to shield non-human primates from SARS-CoV-2 infection

Nature Materials, 2.

By: X. Mei n, J. Li n, Z. Wang n, D. Zhu nโ€‰, K. Huang nโ€‰, S. Hu nโ€‰, K. Popowski nโ€‰, K. Cheng

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
Sources: Web Of Science, ORCID, Crossref
Added: March 6, 2023

2023 journal article

Tissue clearing and three-dimensional imaging of the whole cochlea and vestibular system from multiple large-animal models

STAR PROTOCOLS, 4(2).

By: A. Moatti nโ€‰, Y. Cai n, C. Li n, K. Popowski nโ€‰, K. Cheng n, F. Ligler*, A. Greenbaum n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: imaged cochleae using open -source software.; several mm; larger animal inner; open -source software
Source: Web Of Science
Added: September 5, 2023

2022 article

Decoy Exosomes Offer Protection Against Chemotherapy-Induced Toxicity

Fan, M., Li, H., Shen, D., Wang, Z., Liu, H., Zhu, D., โ€ฆ Li, Z. (2022, September 4). ADVANCED SCIENCE, Vol. 9.

By: M. Fan*, H. Liโ€‰*, D. Shenโ€‰*, Z. Wang*, H. Liuโ€‰*, D. Zhu nโ€‰, Z. Wang n, L. Li* ...

co-author countries: China ๐Ÿ‡จ๐Ÿ‡ณ United Kingdom of Great Britain and Northern Ireland ๐Ÿ‡ฌ๐Ÿ‡ง United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: cardio-oncology; cardiotoxicity; chemotherapy; exosome; tetrahedral DNA nanostructure
MeSH headings : Humans; Exosomes / genetics; Exosomes / metabolism; Cardiotoxicity / etiology; Cardiotoxicity / prevention & control; Cardiotoxicity / metabolism; Quality of Life; Neoplasms; Antineoplastic Agents / toxicity; Antineoplastic Agents / metabolism; Chemical and Drug Induced Liver Injury / metabolism
Sources: Web Of Science, ORCID
Added: September 12, 2022

2022 article

Exosomes decorated with a recombinant SARS-CoV-2 receptor-binding domain as an inhalable COVID-19 vaccine

Wang, Z., Popowski, K. D., Zhu, D., Abad, B. L. de J., Wang, X., Liu, M., โ€ฆ Cheng, K. (2022, July 4). NATURE BIOMEDICAL ENGINEERING, Vol. 7.

By: Z. Wang n, K. Popowski nโ€‰, D. Zhu nโ€‰, B. Abadโ€‰ n, X. Wang n, M. Liu n, H. Lutz n, N. De Naeyer* ...

co-author countries: China ๐Ÿ‡จ๐Ÿ‡ณ United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Antibodies, Neutralizing; CD8-Positive T-Lymphocytes; COVID-19 / prevention & control; COVID-19 Vaccines; Exosomes; Humans; Mice; Mice, Inbred BALB C; SARS-CoV-2; Viral Vaccines
Sources: Web Of Science, ORCID
Added: July 11, 2022

2022 journal article

Inhalable dry powder mRNA vaccines based on extracellular vesicles

Matter, 5(9), 2960โ€“2974.

By: K. Popowski nโ€‰, A. Moatti nโ€‰, G. Scull n, D. Silkstone n, H. Lutz n, B. Lรณpez de Juan Abadโ€‰ n, A. George nโ€‰, E. Belcherโ€‰ n ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
Sources: Web Of Science, ORCID, Crossref
Added: October 17, 2022

2022 journal article

Inhalable exosomes outperform liposomes as mRNA and protein drug carriers to the lung

Extracellular Vesicle.

By: K. Popowski nโ€‰, B. Juan Abadโ€‰ n, A. Georgeโ€‰ n, D. Silkstone n, E. Belcherโ€‰ n, J. Chungโ€‰ n, A. Ghodsi n, H. Lutzโ€‰ n ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
Source: ORCID
Added: June 16, 2022

2022 journal article

Intrapericardial hydrogel injection generates high cell retention and augments therapeutic effects of mesenchymal stem cells in myocardial infarction

CHEMICAL ENGINEERING JOURNAL, 427.

By: J. Li n, Y. Lvโ€‰*, D. Zhu nโ€‰, X. Mei n, K. Huang nโ€‰, X. Wang n, Z. Li n, S. Zhang n ...

co-author countries: China ๐Ÿ‡จ๐Ÿ‡ณ United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: J. Li n, Y. Lvโ€‰*, D. Zhu nโ€‰, X. Mei n, K. Huang nโ€‰, X. Wang n, Z. Li n, S. Zhang n ...

author keywords: Mesenchymal stem cells; Hydrogel; Myocardial infarction; Intrapericardial; Intramyocardial
Sources: Web Of Science, ORCID
Added: January 3, 2022

2021 journal article

Advanced Nanobiomedical Approaches to Combat Coronavirus Disease of 2019

Advanced NanoBiomed Research, 1(3), 2000063.

By: H. Lutzโ€‰ n, K. Popowski nโ€‰, P. Dinhโ€‰ n & K. Chengโ€‰ n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: coronavirus disease; exosomes; nanomedicine; severe acute respiratory syndrome coronavirus 2; therapeutics; vaccines
Source: ORCID
Added: June 8, 2022

2021 journal article

Cell-mimicking nanodecoys neutralize SARS-CoV-2 and mitigate lung injury in a non-human primate model of COVID-19

Nature Nanotechnology, 6(8), 942โ€“951.

By: Z. Liโ€‰ n, Z. Wangโ€‰ n, P. Dinhโ€‰ n, D. Zhu nโ€‰, K. Popowski nโ€‰, H. Lutzโ€‰ n, S. Huโ€‰ n, M. Lewisโ€‰* ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: Z. Liโ€‰ n, Z. Wangโ€‰ n, P. Dinhโ€‰ n, D. Zhu nโ€‰, K. Popowski nโ€‰, H. Lutzโ€‰ n, S. Huโ€‰ n, M. Lewisโ€‰* ...

MeSH headings : Administration, Inhalation; Angiotensin-Converting Enzyme 2 / metabolism; Animals; COVID-19 / virology; Cell-Derived Microparticles / metabolism; Cell-Derived Microparticles / transplantation; Disease Models, Animal; Humans; Lung Injury / prevention & control; Lung Injury / virology; Macaca fascicularis; Mice; Nanostructures / administration & dosage; Protein Binding; SARS-CoV-2 / drug effects; SARS-CoV-2 / metabolism; Spheroids, Cellular / metabolism; Spike Glycoprotein, Coronavirus / metabolism; Viral Load / drug effects; COVID-19 Drug Treatment
Source: ORCID
Added: June 18, 2021

2021 article

Enhancement of Bone Regeneration Through the Converse Piezoelectric Effect, A Novel Approach for Applying Mechanical Stimulation

Carter, A., Popowski, K., Cheng, K., Greenbaum, A., Ligler, F. S., & Moatti, A. (2021, September 24). BIOELECTRICITY, Vol. 9.

By: A. Carter n, K. Popowski nโ€‰, K. Cheng n, A. Greenbaum n, F. Ligler n & A. Moatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: converse piezoelectric effect; mechanical stimulation; bone regeneration
Sources: Web Of Science, ORCID
Added: September 25, 2021

2021 review

Exosome therapeutics for COVID-19 and respiratory viruses

[Review of ]. VIEW, 2(3).

By: K. Popowski nโ€‰, P. Dinh n, A. George nโ€‰, H. Lutz n & K. Cheng n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: COVID-19; exosomes; respiratory viruses; SARS-CoV-2
Sources: Web Of Science, ORCID
Added: July 19, 2021

2020 journal article

Exosome and Biomimetic Nanoparticle Therapies for Cardiac Regenerative Medicine

Current Stem Cell Research & Therapy, 15(8), 674โ€“684.

By: S. Stine n, K. Popowski nโ€‰, T. Su n & K. Chengโ€‰ n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Exosomes; regenerative medicine; biomimetic nanoparticles; drug delivery; extracellular vesicles; mesenchymal stem cells; secretome
MeSH headings : Biomimetics; Exosomes; Heart Diseases / therapy; Nanoparticles; Regenerative Medicine; Reproducibility of Results
Source: ORCID
Added: June 8, 2022

2020 review

Exosome therapeutics for lung regenerative medicine

[Review of ]. JOURNAL OF EXTRACELLULAR VESICLES, 9(1).

By: K. Popowski nโ€‰, H. Lutz n, S. Hu nโ€‰, A. George nโ€‰, P. Dinh n & K. Cheng*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Exosome; regenerative medicine; lung spheroid cell; stem cell
Sources: Web Of Science, ORCID
Added: July 20, 2020

2020 journal article

Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis

NATURE COMMUNICATIONS, 11(1).

By: P. Dinh n, D. Paudel n, H. Brochu n, K. Popowski nโ€‰, M. Gracieux n, J. Cores n, K. Huang nโ€‰, M. Hensley n ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Administration, Inhalation; Alveolar Epithelial Cells / drug effects; Alveolar Epithelial Cells / metabolism; Alveolar Epithelial Cells / pathology; Animals; Apoptosis / drug effects; Bleomycin / toxicity; Cell Proliferation; Disease Models, Animal; Exosomes / metabolism; Exosomes / transplantation; Humans; Idiopathic Pulmonary Fibrosis / chemically induced; Idiopathic Pulmonary Fibrosis / metabolism; Idiopathic Pulmonary Fibrosis / pathology; Idiopathic Pulmonary Fibrosis / therapy; Lung / cytology; Lung / metabolism; Lung Injury / chemically induced; Lung Injury / metabolism; Lung Injury / pathology; Lung Injury / therapy; Mesenchymal Stem Cells / metabolism; Mice; Myofibroblasts / cytology; Proteomics; Silicon Dioxide / toxicity; Spheroids, Cellular / metabolism
Sources: Web Of Science, ORCID
Added: March 23, 2020

Employment

Updated: May 16th, 2023 15:35

2023 - present

Immorna Biotherapeutics Raleigh, US
Scientist

Education

Updated: May 16th, 2023 15:36

2018 - 2023

North Carolina State University Raleigh, North Carolina, US
PhD Comparative Biomedical Sciences