KaLynn Harlow

Works (9)

Updated: July 12th, 2023 17:05

2022 article

The impact of undernutrition on KNDy (kisspeptin/neurokinin B/dynorphin) neurons in female lambs

Harlow, K. L., Griesgraber, M. J., Seman, A. D., Shuping, S. L., Sommer, J. R., Griffith, E. H., … Nestor, C. C. (2022, May 17). JOURNAL OF NEUROENDOCRINOLOGY, Vol. 5.

By: K. Harlow n , M. Griesgraber *, A. Seman*, S. Shuping n, J. Sommer n, E. Griffith n , S. Hileman *, C. Nestor n 

author keywords: dynorphin; kisspeptin; LH; neurokinin B; undernutrition; xxxx; fx1
MeSH headings : Animals; Arcuate Nucleus of Hypothalamus / metabolism; Body Weight; Dynorphins / metabolism; Female; Gonadotropin-Releasing Hormone / metabolism; Kisspeptins / metabolism; Malnutrition / metabolism; Neurokinin B / metabolism; Neurons / metabolism; RNA, Messenger / metabolism; Sheep
topics (OpenAlex): Hypothalamic control of reproductive hormones; Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities; Sperm and Testicular Function
TL;DR: The idea that KNDy neurons are important for regulating reproduction during undernutrition in female sheep is supported, as lower mRNA abundance for kisspeptin within K NDy neurons of FR lambs compared to controls with no significant change in mRNA for NKB or dynorphin is observed. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: April 14, 2022

2021 journal article

Evidence that pubertal status impacts kisspeptin/neurokinin B/dynorphin neurons in the gilt(dagger)

BIOLOGY OF REPRODUCTION, 105(6), 1533–1544.

By: K. Harlow n , A. Renwick  n, S. Shuping n, J. Sommer n, C. Lents *, M. Knauer n, C. Nestor n 

author keywords: kisspeptin; NKB; dynorphin; swine; puberty
MeSH headings : Animals; Arcuate Nucleus of Hypothalamus / metabolism; Dynorphins / metabolism; Female; Kisspeptins / metabolism; Neurokinin B / metabolism; Neurons / physiology; Sexual Maturation; Sus scrofa / physiology
topics (OpenAlex): Hypothalamic control of reproductive hormones; Plant Reproductive Biology; Reproductive Physiology in Livestock
TL;DR: The degree to which KNDy neurons exist in the gilt is characterized for the first time, and the impact of pubertal status on kisspeptin, neurokinin B, and dynorphin in the arcuate nucleus of gilts is examined. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: April 18, 2022

2021 journal article

Kisspeptin, Neurokinin B, and Dynorphin Expression during Pubertal Development in Female Sheep

BIOLOGY-BASEL, 10(10).

By: E. Aerts *, K. Harlow n , M. Griesgraber *, E. Bowdridge *, S. Hardy*, C. Nestor n , S. Hileman *

author keywords: kisspeptin; neurokinin B; dynorphin; puberty; sheep; LH
topics (OpenAlex): Hypothalamic control of reproductive hormones; Plant Reproductive Biology; Ovarian function and disorders
TL;DR: It is concluded that puberty-associated increases in GnRH and LH secretion occur without significant changes in KNDy peptide expression and suggest that, while critical, KNDY neurons await inputs from other neural systems to trigger puberty onset. (via Semantic Scholar)
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Sources: ORCID, Web Of Science, NC State University Libraries
Added: October 2, 2021

2020 article

Effects of genetic selection for early puberty on the hypothalamic-pituitary-ovarian axis in gilts

Harlow, K. L., Renwick, A., Shuping, S., Sommer, J., Knauer, M., & Nestor, C. (2020, November). JOURNAL OF ANIMAL SCIENCE, Vol. 98, pp. 212–212.

By: K. Harlow n , A. Renwick  n, S. Shuping n, J. Sommer n, M. Knauer n & C. Nestor n 

author keywords: puberty; gilt; neuroendocrine
topics (OpenAlex): Animal Nutrition and Physiology; Reproductive Physiology in Livestock
TL;DR: It is concluded that gilts genetically selected for early puberty do so via changes within the hypothalamus that increase gonadotropin secretion and, in turn, stimulate ovarian growth to ultimately advance the timing of puberty onset. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: February 8, 2021

2019 article

Lipidome profiles of postnatal day 2 vaginal swabs reflect fat composition of gilt’s postnatal diet

Harlow, K. L., Ferreira, C. R., Sobreira, T. J. P., Casey, T., & Stewart, K. (2019, March 29). (Vol. 3). Vol. 3.

By: K. Harlow* , C. Ferreira, T. Sobreira, T. Casey * & K. Stewart *

topics (OpenAlex): Reproductive Physiology in Livestock; Adipose Tissue and Metabolism; Fatty Acid Research and Health
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2. Zero Hunger (OpenAlex)
Source: ORCID
Added: November 19, 2019

2019 journal article

Lipidome profiles of postnatal day 2 vaginal swabs reflect fat composition of gilt’s postnatal diet

PLOS ONE.

By: K. Harlow* , C. Ferreira *, T. Sobreira *, T. Casey * & K. Stewart *

Ed(s): J. Loor

MeSH headings : Animal Nutritional Physiological Phenomena; Animals; Animals, Suckling / growth & development; Animals, Suckling / metabolism; Diet; Female; Lipid Metabolism; Lipids / chemistry; Swine / physiology; Vagina / growth & development; Vagina / metabolism
topics (OpenAlex): Reproductive Physiology in Livestock; Fatty Acid Research and Health; Adipose Tissue and Metabolism
TL;DR: Vaginal swab lipidome profiles at 48 h reflect the fat composition of neonatal diet during first two days postnatal, and findings support that vaginal swabs can be used to noninvasively study effects of perinatal nutrition on tissue composition. (via Semantic Scholar)
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2. Zero Hunger (OpenAlex)
Source: ORCID
Added: November 19, 2019

2019 journal article

Temporal analysis of vaginal proteome reveals developmental changes in lower reproductive tract of gilts across the first two weeks postnatal

Scientific Reports.

KaLynn Harlow

MeSH headings : Animals; Animals, Newborn; Female; Gene Expression Regulation, Developmental; Proteome / analysis; Reproduction; Spatio-Temporal Analysis; Swine; Vagina / metabolism
topics (OpenAlex): Reproductive Physiology in Livestock; Molecular Biology Techniques and Applications; Veterinary Medicine and Surgery
TL;DR: Changes in cytology and proteome over the first two weeks after birth support that the porcine vagina continues to develop postnatal. (via Semantic Scholar)
Source: ORCID
Added: January 13, 2020

2018 journal article

Diet Impacts Pre-implantation Histotroph Proteomes in Beef Cattle

Journal of Proteome Research.

KaLynn Harlow

author keywords: proteome; histotroph; cow; nutrition; liquid chromatograph-tandem mass spectrometry; LC-MS/MS
MeSH headings : Animals; Breeding; Cattle; Chromatography, Liquid; Diet; Embryo Implantation; Female; Proteome; Red Meat; Tandem Mass Spectrometry
topics (OpenAlex): Reproductive Physiology in Livestock; Sperm and Testicular Function; Reproductive System and Pregnancy
TL;DR: Differences in proteomes among treatments support the idea that pre-breeding diet affects histotroph proteins in beef cattle, and may help improve conception rates. (via Semantic Scholar)
Source: ORCID
Added: January 13, 2020

2018 journal article

The potential of identifying replacement gilts by screening for lipid biomarkers in reproductive tract swabs taken at weaning

Journal of Applied Animal Research.

KaLynn Harlow

author keywords: Colostrum; gilt; reproduction; metabolomics; biomarker
topics (OpenAlex): Reproductive Physiology in Livestock; Animal Behavior and Welfare Studies; Genetic and phenotypic traits in livestock
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UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: ORCID
Added: January 13, 2020

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